Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of chromatin

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

6.64e-07100626GO:0030527
GeneOntologyBiologicalProcessnucleosome assembly

H3C1 TSPYL2 H3-3A H3-4 H3C15

3.04e-05122615GO:0006334
GeneOntologyBiologicalProcesschromatin organization

UBR2 SAFB H3C1 KMT5C MDC1 TSPYL2 DDX23 H3-3A CHD7 H3-4 H3C15

5.58e-058966111GO:0006325
GeneOntologyBiologicalProcessnucleosome organization

H3C1 TSPYL2 H3-3A H3-4 H3C15

6.29e-05142615GO:0034728
GeneOntologyCellularComponentnucleosome

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

3.37e-06138626GO:0000786
GeneOntologyCellularComponentchromatin

UBR2 SIN3B GRHL1 H3-5 H3C1 KMT5C POLR2A TSPYL2 DDX23 H3-3A ELF3 CHD7 H3-4 PIAS2 H3-7 H3C15

4.45e-0614806216GO:0000785
GeneOntologyCellularComponentX chromosome

SIN3B H3-3A

6.61e-0413622GO:0000805
MousePhenoabnormal periosteum morphology

CHD7 SMPD3

3.17e-053462MP:0010971
DomainHISTONE_H3_1

H3-5 H3C1 H3-3A H3-4

3.34e-097604PS00322
DomainH3

H3-5 H3C1 H3-3A H3-4

6.67e-098604SM00428
DomainHISTONE_H3_2

H3-5 H3C1 H3-3A H3-4

6.67e-098604PS00959
DomainHistone_H3/CENP-A

H3-5 H3C1 H3-3A H3-4

6.67e-098604IPR000164
DomainHistone

H3-5 H3C1 H3-3A H3-4

3.12e-0556604PF00125
DomainHistone_H2A/H2B/H3

H3-5 H3C1 H3-3A H3-4

3.12e-0556604IPR007125
Domain-

SAFB SAFB2 PIAS2

4.02e-05216031.10.720.30
DomainSAP

SAFB SAFB2 PIAS2

4.65e-0522603PF02037
DomainSAP

SAFB SAFB2 PIAS2

5.33e-0523603SM00513
DomainSAP

SAFB SAFB2 PIAS2

6.89e-0525603PS50800
DomainSAP_dom

SAFB SAFB2 PIAS2

6.89e-0525603IPR003034
Domain-

H3-5 H3C1 H3-3A H3-4

7.12e-05696041.10.20.10
DomainHistone-fold

H3-5 H3C1 H3-3A H3-4

1.46e-0483604IPR009072
DomainComplex1_LYR

SDHAF1 LYRM9

4.49e-0410602IPR008011
DomainComplex1_LYR

SDHAF1 LYRM9

4.49e-0410602PF05347
DomainCa/CaM-dep_Ca-dep_prot_Kinase

PHKG1 MARK3 AURKB

1.42e-0369603IPR020636
DomainFN3

MPL PAPPA2 SDK2 ROBO2

2.95e-03185604SM00060
DomainTPR_1

SH3TC2 PEX5 TTC1

3.04e-0390603PF00515
DomainTPR_1

SH3TC2 PEX5 TTC1

3.04e-0390603IPR001440
DomainFN3_dom

MPL PAPPA2 SDK2 ROBO2

4.56e-03209604IPR003961
DomainTPR

SH3TC2 PEX5 TTC1

8.27e-03129603SM00028
DomainTPR_repeat

SH3TC2 PEX5 TTC1

8.99e-03133603IPR019734
PathwayKEGG_MEDICUS_VARIANT_IGH_MMSET_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION

H3-5 H3C1 H3-3A H3-4 H3C15

4.14e-0919485M47442
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

H3C1 POLR2A H3-3A PIAS2 H3C15

5.69e-05122485M29689
PathwayWP_HISTONE_MODIFICATIONS

H3C1 KMT5C H3-3A H3C15

6.88e-0565484M39374
PathwayKEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS

H3-5 H3C1 H3-3A H3-4 H3C15

1.06e-04139485M4741
PathwayREACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

H3C1 H3-3A H3-4 H3C15

1.08e-0473484M27166
PathwayWP_FBXL10_ENHANCEMENT_OF_MAPERK_SIGNALING_IN_DIFFUSE_LARGE_BCELL_LYMPHOMA

H3C1 H3-3A H3C15

1.88e-0433483M39800
PathwayREACTOME_MEIOTIC_RECOMBINATION

H3C1 H3-3A H3-4 H3C15

2.24e-0488484M1011
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

H3C1 H3-3A H3-4 H3C15

2.54e-0491484M27101
PathwayWP_EFFECT_OF_PROGERIN_ON_GENES_INVOLVED_IN_PROGERIA

H3C1 H3-3A H3C15

2.65e-0437483M39756
PathwayREACTOME_RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DIFFERENTIATION_AND_PLATELET_FUNCTION

SIN3B H3C1 H3-3A H3C15

3.12e-0496484M27792
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

H3C1 POLR2A H3-3A H3C15

4.56e-04106484M27458
PathwayREACTOME_NEGATIVE_EPIGENETIC_REGULATION_OF_RRNA_EXPRESSION

SIN3B H3C1 H3-3A H3C15

4.89e-04108484M27426
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

H3C1 H3-3A ELF3 H3C15

7.05e-04119484M607
PathwayREACTOME_MEIOSIS

H3C1 H3-3A H3-4 H3C15

7.28e-04120484M529
PathwayKEGG_MEDICUS_REFERENCE_TRANSCRIPTIONAL_ACTIVATION_BY_ACETYLATION_OF_H3K27

H3C1 H3-3A

1.16e-0315482M47973
PathwayREACTOME_GENE_SILENCING_BY_RNA

H3C1 POLR2A H3-3A H3C15

1.26e-03139484M715
PathwayREACTOME_DNA_METHYLATION

H3C1 H3-3A H3C15

1.33e-0364483M27429
PathwayREACTOME_MITOTIC_PROPHASE

H3C1 H3-3A H3-4 H3C15

1.36e-03142484M27660
PathwayREACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3

H3C1 H3-3A H3C15

1.46e-0366483M27488
PathwayREACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

H3C1 H3-3A H3C15

1.52e-0367483M27342
PathwayREACTOME_INHIBITION_OF_DNA_RECOMBINATION_AT_TELOMERE

POLR2A H3-3A H3-4

1.52e-0367483M39003
PathwayREACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

H3C1 H3-3A H3C15

1.59e-0368483M27658
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

H3C1 POLR2A H3-3A H3C15

1.63e-03149484M27888
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_THE_HUMAN_SILENCING_HUB_HUSH_COMPLEX

H3C1 H3-3A H3C15

1.73e-0370483M48261
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

H3C1 KMT5C H3C15

1.73e-0370483M27231
PathwayREACTOME_CHROMATIN_MODIFICATIONS_DURING_THE_MATERNAL_TO_ZYGOTIC_TRANSITION_MZT

H3C1 H3-3A H3C15

1.73e-0370483M48028
PathwayREACTOME_PRC2_METHYLATES_HISTONES_AND_DNA

H3C1 H3-3A H3C15

1.87e-0372483M27132
PathwayREACTOME_REPRODUCTION

H3C1 H3-3A H3-4 H3C15

2.01e-03158484M26956
PathwayREACTOME_ERCC6_CSB_AND_EHMT2_G9A_POSITIVELY_REGULATE_RRNA_EXPRESSION

H3C1 H3-3A H3C15

2.11e-0375483M27343
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

POLR2A STEEP1 RBM5 DDX23 CLP1

2.43e-03277485MM15414
Pubmed

Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation.

H3-3A H3-7 H3C15 AURKB

3.19e-10762411856369
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

ADORA2A SAFB H3-5 H3C1 MARK3 MDC1 STEEP1 SAFB2 DDX23 H3-4 H3-7 H3C15 AURKB ATP5F1C

9.94e-10949621436574265
Pubmed

Crystal structure of DPF3b in complex with an acetylated histone peptide.

H3-5 H3C1 H3-3A H3-4

1.15e-09962427402533
Pubmed

Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1.

H3C1 H3-3A H3-7 H3C15

2.99e-091162415471871
Pubmed

Human PAD4 regulates histone arginine methylation levels via demethylimination.

H3-3A H3-4 H3-7 H3C15

2.99e-091162415345777
Pubmed

A standardized nomenclature for mammalian histone genes.

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

4.22e-097462636180920
Pubmed

Expression patterns and post-translational modifications associated with mammalian histone H3 variants.

H3C1 H3-3A H3-7 H3C15

9.04e-091462416267050
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SAFB H3-5 H3C1 POLR2A MDC1 STEEP1 SAFB2 H3-3A CHD7 H3-4 H3C15 PRRC2A ATP5F1C

1.10e-08954621336373674
Pubmed

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

H3C1 H3-3A H3-7 H3C15

5.35e-082162411242053
Pubmed

Modifications of human histone H3 variants during mitosis.

H3-3A H3-7 H3C15

5.38e-08562316185088
Pubmed

Human spleen histone H3. Isolation and amino acid sequence.

H3-3A H3-7 H3C15

5.38e-0856237309716
Pubmed

Large-scale cDNA transfection screening for genes related to cancer development and progression.

FBXO38 SH3TC2 NEU4 KMT5C H3-3A ABHD16A

5.75e-0811462615498874
Pubmed

Organismal differences in post-translational modifications in histones H3 and H4.

H3-3A H3-7 H3C15

1.07e-07662317194708
Pubmed

Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.

H3-3A H3-7 H3C15

1.07e-07662310464286
Pubmed

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks.

H3-3A H3-7 H3C15

1.07e-07662315525939
Pubmed

Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase.

H3-3A H3-7 H3C15

1.07e-07662312560483
Pubmed

Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification.

H3-3A H3-7 H3C15

1.07e-07662317189264
Pubmed

Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha.

H3-3A H3-7 H3C15

1.88e-07762315684425
Pubmed

PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity.

H3C1 H3-3A H3-4

1.88e-07762320448663
Pubmed

The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.

H3-3A H3-7 H3C15

1.88e-07762315681610
Pubmed

Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17.

H3-3A H3-7 H3C15

1.88e-07762316497732
Pubmed

Human tNASP promotes in vitro nucleosome assembly with histone H3.3.

H3C1 H3-3A H3-4 H3C15

2.78e-073162425615412
Pubmed

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.

SAFB H3C1 POLR2A SAFB2 H3-3A H3C15

1.10e-0618862629721183
Pubmed

Serine ADP-Ribosylation Depends on HPF1.

H3C1 H3-3A H3-4

2.42e-061562328190768
Pubmed

Human Asf1 regulates the flow of S phase histones during replicational stress.

H3C1 H3-3A H3-4

2.97e-061662315664198
Pubmed

Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis?

SAFB SAFB2

3.13e-06262214587024
Pubmed

SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.

SAFB SAFB2

3.13e-06262219901029
Pubmed

A unique H3K4me2 profile marks tissue-specific gene regulation.

H3-3A H3-4

3.13e-06262220841431
Pubmed

No germline mutations in supposed tumour suppressor genes SAFB1 and SAFB2 in familial breast cancer with linkage to 19p.

SAFB SAFB2

3.13e-06262219077293
Pubmed

Low SAFB levels are associated with worse outcome in breast cancer patients.

SAFB SAFB2

3.13e-06262219137425
Pubmed

An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation.

POLR2A H3-3A

3.13e-06262224430871
Pubmed

Aurora Kinase B Phosphorylates Histone H3.3 at Serine 31 during Mitosis in Mammalian Cells.

H3-3A AURKB

3.13e-06262228137420
Pubmed

Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells.

SAFB SAFB2

3.13e-06262226273616
Pubmed

Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1.

SAFB SAFB2

3.13e-06262226092125
Pubmed

Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα.

SAFB SAFB2

3.13e-06262222566185
Pubmed

Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7.

H3C1 H3-4 H3C15

4.32e-061862312489984
Pubmed

Np95 is a histone-binding protein endowed with ubiquitin ligase activity.

H3C1 H3-3A H3-4

6.02e-062062314993289
Pubmed

Characterization of single-nucleotide polymorphisms in coding regions of human genes.

MPL ADORA2A HTR1D F13A1

6.45e-066762410391209
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

SAFB POLR2A MDC1 SAFB2 RBM5 DDX23 H3-7 H3C15 AURKB ATP5F1C

9.30e-06989621036424410
Pubmed

CBX3 regulates efficient RNA processing genome-wide.

POLR2A H3-3A

9.37e-06362222684280
Pubmed

The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.

SAFB SAFB2

9.37e-06362219674106
Pubmed

H3.5 is a novel hominid-specific histone H3 variant that is specifically expressed in the seminiferous tubules of human testes.

H3-5 H3-3A

9.37e-06362221274551
Pubmed

Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase.

H3C1 POLR2A

9.37e-06362216118227
Pubmed

Human lymphocyte antigen B-associated transcript 2, 3, and 5 polymorphisms and haplotypes are associated with susceptibility of Kawasaki disease and coronary artery aneurysm.

PRRC2A ABHD16A

9.37e-06362220626023
Pubmed

Molecular recognition of histone H3 by the WD40 protein WDR5.

H3C1 H3C15

9.37e-06362216829960
Pubmed

Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.

H3C1 H3C15

9.37e-06362216829959
Pubmed

Methylation-mediated control of aurora kinase B and Haspin with epigenetically modified histone H3 N-terminal peptides.

H3C1 AURKB

9.37e-06362221397507
Pubmed

CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis.

H3C1 AURKB

9.37e-06362211756469
Pubmed

Cre/lox Studies Identify Resident Macrophages as the Major Source of Circulating Coagulation Factor XIII-A.

MPL F13A1

9.37e-06362228596376
Pubmed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

SAFB H3C1 MDC1 SAFB2 DDX23 H3-3A H3-4 H3C15 ATP5F1C

1.02e-0578662929128334
Pubmed

The human and mouse replication-dependent histone genes.

H3C1 H3-4 H3-7 H3C15

1.12e-057762412408966
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

FBXO38 SIN3B MDC1 STEEP1 H3-3A CHD7 PIAS2 AURKB

1.23e-0560862836089195
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SIN3B SAFB H3C1 POLR2A MDC1 STEEP1 SAFB2 RBM5 DDX23 CHD7 ATP5F1C

1.61e-051294621130804502
Pubmed

Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones.

H3C1 POLR2A H3-3A H3-4

1.74e-058662411080476
Pubmed

Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection.

H3C1 H3-3A

1.87e-05462225275136
Pubmed

Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage.

H3-3A AURKB

1.87e-05462216179389
Pubmed

SAFB1 interacts with and suppresses the transcriptional activity of p53.

SAFB SAFB2

1.87e-05462221130767
Pubmed

Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C.

H3C1 AURKB

1.87e-05462215316025
Pubmed

VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis.

H3-4 AURKB

1.87e-05462229340707
Pubmed

Identification and characterization of propionylation at histone H3 lysine 23 in mammalian cells.

H3C1 H3C15

1.87e-05462219801601
Pubmed

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.

H3C1 H3-4

1.87e-05462227595565
Pubmed

RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation.

POLR2A RPAP2

1.87e-05462224997600
Pubmed

Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation.

H3C1 H3-4

1.87e-05462216858404
Pubmed

Selective amplification and cloning of four new members of the G protein-coupled receptor family.

ADORA2A HTR1D

1.87e-0546222541503
Pubmed

Transcription Dynamics Prevent RNA-Mediated Genomic Instability through SRPK2-Dependent DDX23 Phosphorylation.

POLR2A DDX23

1.87e-05462228076779
Pubmed

Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor.

ADORA2A HTR1D

1.87e-0546221662665
Pubmed

Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3.

H3C1 H3-4

1.87e-05462217599839
Pubmed

SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor.

SAFB SAFB2

1.87e-05462212660241
Pubmed

JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin.

H3C1 H3-4

1.87e-05462219783980
Pubmed

Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3.

H3C1 H3-4

1.87e-05462210436156
Pubmed

SUMOylation modulates the function of Aurora-B kinase.

H3-4 AURKB

1.87e-05462220663916
Pubmed

Scaffold attachment factor SAFB1 suppresses estrogen receptor alpha-mediated transcription in part via interaction with nuclear receptor corepressor.

SAFB SAFB2

1.87e-05462216195251
Pubmed

Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.

H3C1 H3-4

1.87e-05462211779497
Pubmed

Structures of human nucleosomes containing major histone H3 variants.

H3C1 H3-3A H3C15

1.91e-052962321636898
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

SAFB POLR2A MDC1 SAFB2 DDX23 H3-3A H3-7 H3C15

2.03e-0565262831180492
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

SDK2 SAFB POLR2A MDC1 RBM5 DDX23 PIAS2 RPAP2

2.46e-0567062822990118
Pubmed

Transcription through the nucleosome.

H3C1 H3-4 H3C15

2.83e-053362331790919
Pubmed

DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network.

H3C1 H3-3A H3C15

2.83e-053362333857403
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

FBXO38 SAFB POLR2A MDC1 SAFB2 PIAS2

2.84e-0533262632786267
Pubmed

SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins.

H3-4 H3C15

3.12e-05562211959841
Pubmed

Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583.

H3C1 POLR2A

3.12e-05562217050672
Pubmed

TSPYL2 Regulates the Expression of EZH2 Target Genes in Neurons.

H3C1 TSPYL2

3.12e-05562230051352
Pubmed

Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion.

MPL F13A1

3.12e-05562220086247
Pubmed

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation.

H3C1 H3C15

3.12e-05562217967883
Pubmed

HIV-1 Tat interactions with p300 and PCAF transcriptional coactivators inhibit histone acetylation and neurotrophin signaling through CREB.

H3C1 H3-4

3.12e-05562215611041
Pubmed

Human histone acetyltransferase 1 protein preferentially acetylates H4 histone molecules in H3.1-H4 over H3.3-H4.

H3C1 H3-4

3.12e-05562222228774
Pubmed

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain.

H3C1 H3-3A

3.12e-05562219834512
Pubmed

Identification of a recombinational breakpoint at the BAT5 locus in three intra-H-2 recombinant inbred mouse strains.

PRRC2A ABHD16A

3.12e-0556228919359
Pubmed

PHF8 targets histone methylation and RNA polymerase II to activate transcription.

H3C1 POLR2A

3.12e-05562220421419
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

H3C1 H3-3A H3-4

3.39e-053562327142060
Pubmed

A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.

H3C1 H3-3A H3C15

3.69e-053662326167883
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SAFB H3-5 H3C1 SAFB2 RBM5 DDX23 H3-3A ITIH6 H3-4 H3C15 ATP5F1C

4.35e-051442621135575683
Pubmed

Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis.

H3C1 H3-3A H3-4

4.35e-053862314718166
Pubmed

Comprehensive proteomic analysis of the human spliceosome.

POLR2A RBM5 DDX23 CLP1

4.43e-0510962412226669
Pubmed

Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.

SAFB PIAS2 PRRC2A ABHD16A

4.59e-0511062414667819
Pubmed

Tumour suppressor CYLD is a negative regulator of the mitotic kinase Aurora-B.

H3-4 AURKB

4.67e-05662220593489
Pubmed

EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A.

H3C1 AURKB

4.67e-05662218477699
Pubmed

Crosstalk between CARM1 methylation and CBP acetylation on histone H3.

H3C1 H3-3A

4.67e-05662212498683
Pubmed

Histone deimination antagonizes arginine methylation.

H3-3A H3C15

4.67e-05662215339660
Pubmed

Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.

H3C1 H3-4

4.67e-05662224235145
InteractionH2BC9 interactions

ADAMTS19 H3-5 H3C1 POLR2A MDC1 SAFB2 RBM5 H3-3A H3-4 H3-7 H3C15 PRRC2A

5.20e-094465912int:H2BC9
InteractionHMGA1 interactions

FBXO38 H3-5 H3C1 POLR2A MDC1 SAFB2 H3-3A H3-4 H3-7 H3C15

3.43e-074195910int:HMGA1
InteractionMYLK2 interactions

SAFB H3-5 H3C1 POLR2A H3-3A H3-4

4.96e-07101596int:MYLK2
InteractionASF1A interactions

FBXO38 H3C1 POLR2A MDC1 STEEP1 H3-3A CHD7 H3-4

6.25e-07249598int:ASF1A
InteractionH2BC21 interactions

H3-5 H3C1 POLR2A MDC1 SAFB2 H3-3A CHD7 H3-4 H3-7 H3C15 PRRC2A AURKB

6.62e-076965912int:H2BC21
InteractionHMGXB4 interactions

SIN3B H3C1 TSPYL2 H3-3A H3-4 PIAS2

9.62e-07113596int:HMGXB4
InteractionRECQL5 interactions

H3C1 POLR2A MDC1 DDX23 H3-3A RPAP2

1.01e-06114596int:RECQL5
InteractionH3-5 interactions

H3-5 H3C1 H3-3A H3-4 H3C15 AURKB

1.01e-06114596int:H3-5
InteractionH2AC12 interactions

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

1.24e-06118596int:H2AC12
InteractionH3-3A interactions

FBXO38 H3-5 H3C1 MDC1 STEEP1 DDX23 H3-3A CHD7 H3-4 PIAS2 H3C15 AURKB

1.43e-067495912int:H3-3A
InteractionH2AJ interactions

H3-5 H3C1 H3-3A H3-4 H3C15 PRRC2A

1.91e-06127596int:H2AJ
InteractionTPX2 interactions

H3C1 MARK3 MDC1 SAFB2 H3-3A PRRC2A AURKB

2.15e-06204597int:TPX2
InteractionKDM5A interactions

SIN3B H3C1 H3-3A H3-4 H3C15

2.50e-0674595int:KDM5A
InteractionH2BC13 interactions

H3-5 H3C1 POLR2A H3-3A H3-4 H3-7 H3C15

2.60e-06210597int:H2BC13
InteractionLOC102724334 interactions

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

2.61e-06134596int:LOC102724334
InteractionH2AC13 interactions

H3-5 H3C1 H3-3A H3-4 H3C15

2.67e-0675595int:H2AC13
InteractionSETD2 interactions

H3C1 POLR2A MDC1 DDX23 H3-4 AURKB

2.72e-06135596int:SETD2
InteractionH2AC14 interactions

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

3.96e-06144596int:H2AC14
InteractionH2AC20 interactions

UBR2 H3-5 H3C1 H3-3A H3-4 H3-7 H3C15 AURKB

4.06e-06320598int:H2AC20
InteractionH2AC18 interactions

H3-5 H3C1 H3-3A H3-4 H3C15 AURKB

4.63e-06148596int:H2AC18
InteractionH2AC25 interactions

H3-5 H3C1 H3-3A H3-4 H3C15

4.68e-0684595int:H2AC25
InteractionSMC5 interactions

SAFB H3-5 H3C1 POLR2A MDC1 STEEP1 SAFB2 H3-3A CHD7 H3-4 H3C15 PRRC2A ATP5F1C

4.93e-0610005913int:SMC5
InteractionCDKN1C interactions

H3C1 POLR2A H3-3A PIAS2

6.19e-0641594int:CDKN1C
InteractionTNIP1 interactions

ADORA2A SAFB H3-5 H3C1 MARK3 MDC1 STEEP1 SAFB2 DDX23 H3-4 H3-7 H3C15 AURKB ATP5F1C

8.16e-0612175914int:TNIP1
InteractionCREBBP interactions

FBXO38 H3C1 POLR2A MDC1 TSPYL2 RBM5 H3-3A ELF3 H3-4 PIAS2

8.45e-065995910int:CREBBP
InteractionH3C1 interactions

H3-5 H3C1 POLR2A MDC1 STEEP1 TSPYL2 H3-3A CHD7 H3-4 H3-7 H3C15 AURKB

9.52e-069015912int:H3C1
InteractionCBX7 interactions

H3C1 H3-3A H3-4 AURKB

9.86e-0646594int:CBX7
InteractionH2AC6 interactions

H3-5 H3C1 H3-3A H3-4 H3C15

1.10e-05100595int:H2AC6
InteractionPHF8 interactions

H3-5 H3C1 POLR2A DDX23 H3-3A H3-4

1.17e-05174596int:PHF8
InteractionH2AC4 interactions

H3-5 H3C1 DDX23 H3-3A H3-4 H3-7 H3C15 PRRC2A AURKB

1.52e-05506599int:H2AC4
InteractionH2AC7 interactions

H3-5 H3C1 H3-3A H3-4 H3C15

1.53e-05107595int:H2AC7
InteractionHNRNPA1 interactions

UBR2 SAFB H3C1 TSPYL2 SAFB2 RBM5 DDX23 H3-3A H3-4 PRRC2A ABHD16A AURKB

1.54e-059455912int:HNRNPA1
InteractionCBX3 interactions

H3C1 KMT5C POLR2A MDC1 STEEP1 H3-3A CHD7 H3-4 H3C15 AURKB

1.63e-056465910int:CBX3
InteractionNSD2 interactions

SIN3B H3C1 POLR2A MDC1 STEEP1 H3-3A H3-4

1.63e-05278597int:NSD2
InteractionH2BC11 interactions

H3-5 H3C1 POLR2A H3-3A H3-4 H3C15

1.71e-05186596int:H2BC11
InteractionCAPN13 interactions

SAFB SAFB2 PRRC2A

2.23e-0519593int:CAPN13
InteractionPHF3 interactions

H3C1 MDC1 DDX23 H3-3A H3-4

2.46e-05118595int:PHF3
InteractionLRWD1 interactions

H3C1 KMT5C DDX23 H3-3A H3-4

2.46e-05118595int:LRWD1
InteractionKDM1B interactions

H3C1 MDC1 H3-3A H3-4

2.50e-0558594int:KDM1B
InteractionNSD1 interactions

H3C1 POLR2A MDC1 H3-3A H3-4

2.56e-05119595int:NSD1
InteractionPHRF1 interactions

POLR2A DDX23 H3-4 RPAP2

3.05e-0561594int:PHRF1
InteractionNASP interactions

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

3.13e-05207596int:NASP
InteractionH3C15 interactions

H3-5 H3C1 H3-3A H3-4 H3C15 AURKB

3.13e-05207596int:H3C15
InteractionCHD1 interactions

SAFB H3C1 DDX23 H3-3A H3-4

3.50e-05127595int:CHD1
InteractionH2BC12 interactions

H3-5 H3C1 POLR2A H3-3A H3-4 H3C15 PRRC2A

4.17e-05322597int:H2BC12
InteractionHMGN2 interactions

H3C1 MDC1 H3-4 H3-7 H3C15 PRRC2A

4.62e-05222596int:HMGN2
InteractionERCC6 interactions

MPL H3C1 POLR2A DDX23 H3-3A ATP5F1C

4.86e-05224596int:ERCC6
InteractionH2BC5 interactions

H3-5 H3C1 POLR2A H3-3A H3-4 H3-7 H3C15

4.96e-05331597int:H2BC5
InteractionZNF780A interactions

FBXO38 H3C1 H3-3A

5.24e-0525593int:ZNF780A
InteractionH2AX interactions

H3-5 H3C1 POLR2A MDC1 DDX23 H3-3A H3-4 H3-7 H3C15

5.26e-05593599int:H2AX
InteractionBRD1 interactions

H3C1 POLR2A TSPYL2 H3-3A H3-4 AURKB RPAP2

6.32e-05344597int:BRD1
InteractionGTF2E1 interactions

H3C1 POLR2A DDX23 H3-3A TTC1

6.38e-05144595int:GTF2E1
InteractionSUV39H1 interactions

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

6.80e-05238596int:SUV39H1
InteractionCPSF3 interactions

MARK3 POLR2A MDC1 DDX23 CLP1

6.81e-05146595int:CPSF3
InteractionRNF169 interactions

FBXO38 H3C1 MDC1 H3-3A

7.26e-0576594int:RNF169
InteractionPIAS1 interactions

SAFB H3C1 MDC1 H3-3A PIAS2 H3C15 ATP5F1C

7.44e-05353597int:PIAS1
InteractionCBX5 interactions

H3-5 H3C1 KMT5C H3-3A H3-4 H3C15 AURKB

7.84e-05356597int:CBX5
InteractionHMGN5 interactions

H3C1 POLR2A MDC1 H3-3A H3C15

8.76e-05154595int:HMGN5
InteractionMLYCD interactions

RBM5 PEX5 MLYCD

9.15e-0530593int:MLYCD
InteractionH3C3 interactions

FBXO38 SIN3B MDC1 STEEP1 CHD7 PIAS2 H3-7 AURKB

9.24e-05495598int:H3C3
InteractionTAF4 interactions

FBXO38 H3C1 POLR2A H3-3A H3-4

9.31e-05156595int:TAF4
InteractionSUZ12 interactions

H3C1 SAFB2 RBM5 DDX23 H3-3A CHD7 H3-4 AURKB ATP5F1C

9.90e-05644599int:SUZ12
InteractionH1-0 interactions

H3-5 H3C1 H3-3A ITIH6 H3-4 H3C15

1.02e-04256596int:H1-0
InteractionATAD5 interactions

H3C1 MDC1 H3-3A H3-7

1.07e-0484594int:ATAD5
InteractionH2BC4 interactions

H3C1 POLR2A H3-3A H3-4 H3C15 PRRC2A

1.08e-04259596int:H2BC4
InteractionRAG1 interactions

H3C1 MDC1 H3-4

1.22e-0433593int:RAG1
InteractionTAF3 interactions

H3C1 DDX23 H3-3A H3-4

1.29e-0488594int:TAF3
InteractionELK4 interactions

H3-5 H3C1 H3-3A H3-4

1.53e-0492594int:ELK4
InteractionSSRP1 interactions

SAFB H3C1 POLR2A SAFB2 DDX23 ROBO2 H3-3A H3C15 PRRC2A

1.58e-04685599int:SSRP1
InteractionMPHOSPH8 interactions

SAFB H3C1 SAFB2 H3-3A

1.59e-0493594int:MPHOSPH8
InteractionMEN1 interactions

SAFB H3C1 POLR2A MDC1 SAFB2 RBM5 DDX23 H3-3A H3-4 PRRC2A AURKB

1.71e-0410295911int:MEN1
InteractionDPF3 interactions

H3-5 H3C1 H3-3A H3-4

1.73e-0495594int:DPF3
InteractionH2BC1 interactions

H3C1 H3-7 H3C15 PRRC2A AURKB

1.73e-04178595int:H2BC1
InteractionZNHIT2 interactions

POLR2A CST4 DDX23 RPAP2

1.80e-0496594int:ZNHIT2
InteractionPABPN1L interactions

H3C1 H3-4 H3C15

1.87e-0438593int:PABPN1L
InteractionCENPC interactions

H3C1 MDC1 DDX23 H3-3A

1.95e-0498594int:CENPC
InteractionH1-3 interactions

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

2.04e-04291596int:H1-3
InteractionDNMT3A interactions

H3C1 POLR2A H3-3A PIAS2

2.45e-04104594int:DNMT3A
InteractionNAT10 interactions

H3C1 DDX23 H3-3A H3-4 H3C15 AURKB

2.49e-04302596int:NAT10
InteractionHPF1 interactions

H3C1 H3-3A H3-4

2.52e-0442593int:HPF1
InteractionH2BC8 interactions

UBR2 MDC1 STEEP1 CHD7 H3-4 PIAS2 H3C15 AURKB

2.61e-04576598int:H2BC8
InteractionZNF512B interactions

PAPPA2 SIN3B H3C1 DDX23 H3-3A

2.70e-04196595int:ZNF512B
InteractionPRDM2 interactions

H3C1 H3-3A H3-4

2.71e-0443593int:PRDM2
InteractionH4C9 interactions

H3C1 H3-3A H3-4 H3-7

2.83e-04108594int:H4C9
InteractionRALBP1 interactions

H3-5 H3C1 POLR2A H3-3A H3-4

2.83e-04198595int:RALBP1
InteractionSET interactions

H3C1 TSPYL2 DDX23 H3-3A H3-4 H3C15

2.92e-04311596int:SET
InteractionPOMZP3 interactions

ADORA2A PRRC2A

2.99e-049592int:POMZP3
InteractionUSP39 interactions

SAFB H3C1 DDX23 H3-3A AURKB

3.04e-04201595int:USP39
InteractionZSCAN18 interactions

SDK2 SAFB2 H3-3A

3.10e-0445593int:ZSCAN18
InteractionH3-4 interactions

SIN3B H3-5 H3C1 H3-3A H3-4 H3C15 AURKB

3.22e-04448597int:H3-4
InteractionCBX4 interactions

H3C1 KMT5C H3-3A TTC1 H3-4

3.32e-04205595int:CBX4
InteractionLIG3 interactions

H3C1 POLR2A MDC1 DDX23 H3-3A

3.48e-04207595int:LIG3
InteractionBIRC5 interactions

MDC1 H3-3A H3-4 AURKB

3.48e-04114594int:BIRC5
InteractionAPLF interactions

CST4 H3-4 H3-7

3.53e-0447593int:APLF
InteractionUHRF1 interactions

FBXO38 H3C1 H3-3A H3-4 H3C15

3.55e-04208595int:UHRF1
InteractionCHD4 interactions

SAFB H3-5 H3C1 MDC1 RBM5 DDX23 H3-3A H3-4 H3C15 ATP5F1C

3.58e-049385910int:CHD4
InteractionGPATCH8 interactions

FBXO38 DDX23 H3-3A H3C15

3.60e-04115594int:GPATCH8
InteractionRAD18 interactions

SAFB H3C1 SAFB2 RBM5 DDX23 H3-3A H3C15

3.63e-04457597int:RAD18
InteractionKDM1A interactions

SIN3B H3-5 H3C1 POLR2A H3-3A CHD7 TTC1 H3-4 CLP1 PIAS2

3.68e-049415910int:KDM1A
InteractionPPM1G interactions

FBXO38 H3C1 MARK3 H3-3A TTC1 H3-4

3.69e-04325596int:PPM1G
Cytoband5q32

FBXO38 SH3TC2 ABLIM3

5.54e-05546235q32
CytobandEnsembl 112 genes in cytogenetic band chr5q32

FBXO38 SH3TC2 ABLIM3

1.79e-0480623chr5q32
Cytoband20p11.21

CST4 SYNDIG1

9.22e-043362220p11.21
Cytoband1q21.2

H3-7 H3C15

4.20e-03716221q21.2
Cytoband6p21.3

MDC1 PRRC2A ABHD16A

4.76e-032506236p21.3
CytobandEnsembl 112 genes in cytogenetic band chr6p21

UBR2 MDC1 PRRC2A ABHD16A

4.81e-03503624chr6p21
GeneFamilyHistones

H3-5 H3C1 H3-3A H3-4 H3-7 H3C15

4.07e-07116456864
GeneFamilyLYR motif containing|NADH:ubiquinone oxidoreductase supernumerary subunits

SDHAF1 LYRM9

2.69e-0410452635
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

SH3TC2 PEX5 TTC1

2.93e-03115453769
ToppCellNS-critical-d_07-13-Epithelial-unknown_epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MPL SIN3B HTR1D H3C1 TSPYL2

1.58e-0614162533ad925ff7be3c682741a6328216a89f9d4033e9
ToppCellNS-critical-d_16-33-Epithelial-unknown_epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

H3C1 POLR2A TSPYL2 SAFB2 RPAP2

4.18e-06172625c0b5e4889aef2f168d9f6db19a63b24bfd249316
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1|Striatum / BrainAtlas - Mouse McCarroll V32

HTR1D SYNDIG1 SMPD3 KCNH3

5.13e-051466247b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SH3TC2 ABLIM3 H3C15 F13A1

7.50e-05161624bfb79277889142133ce86492a808f3083a7547e8
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SH3TC2 ABLIM3 H3C15 F13A1

7.50e-05161624d6f4b0e4e3b2a4e6232a6de3d67b210e24f8c89d
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

ENTPD7 CFAP251 SDK2 SMPD3

9.25e-0517062459cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PHKG1 MDC1 TSPYL2 CHD7

9.46e-05171624bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POLR2A ELF3 HSD11B2 H3C15

9.46e-0517162448125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCellCOPD-Myeloid-pDC|World / Disease state, Lineage and Cell class

ENTPD7 SDK2 TSPYL2 SMPD3

1.01e-04174624be8227398300711ccda5ecc41ad34064bb246b19
ToppCellIPF-Myeloid-pDC|World / Disease state, Lineage and Cell class

ENTPD7 SDK2 TSPYL2 SMPD3

1.03e-04175624a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCellCOPD-Myeloid-pDC|COPD / Disease state, Lineage and Cell class

ENTPD7 SDK2 TSPYL2 SMPD3

1.08e-04177624415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCellIPF-Myeloid-pDC|IPF / Disease state, Lineage and Cell class

ENTPD7 SDK2 TSPYL2 SMPD3

1.10e-041786248d9e28492e1f157bac3308aa947fd864ca16d277
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ENTPD7 SDK2 TSPYL2 SMPD3

1.13e-0417962429b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCellIPF-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ENTPD7 SDK2 TSPYL2 SMPD3

1.15e-041806240f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SDK2 ROBO2 SMPD3 HSD11B2

1.20e-04182624193cb2df3d7ea4cb9a11390b92955e7d9b0a053a
ToppCellremission-Platelet|remission / disease stage, cell group and cell class

SH3TC2 GRHL1 ABLIM3 F13A1

1.20e-0418262465e2798aacd670cbc3a8c8e9d1a2f7768513bb70
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Meis2-Meis2_Adamts19|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADORA2A ADAMTS19 H3-3A

1.22e-0469623130b1a56afe6aee01cde56cb983cbc2c41861bb4
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Meis2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADORA2A ADAMTS19 H3-3A

1.22e-04696236568fcefcc0dca211f2acf6e4066f795489e758d
ToppCellcontrol-Others-Megakaryocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SH3TC2 GRHL1 ABLIM3 F13A1

1.25e-04184624213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCellcontrol-Others|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SH3TC2 GRHL1 ABLIM3 F13A1

1.25e-04184624a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ROBO2 ELF3 KCNH3

1.28e-0418562474b787e225d83efcb84e79c23499febe1a106622
ToppCellmegakaryocytic-Platelet|megakaryocytic / Lineage and Cell class

GRHL1 H3-3A ABLIM3 F13A1

1.28e-04185624436f0ab9016c5b8b7315d5974de80af6b3a999d2
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1D ROBO2 SYNDIG1 SMPD3

1.39e-04189624851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCellHealthy-Platelet|Healthy / disease group, cell group and cell class

GRHL1 H3-3A ABLIM3 F13A1

1.39e-041896245863e132536594e49bffbb637454cc43dfdbaa20
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1D ROBO2 SYNDIG1 SMPD3

1.39e-041896243e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1D ROBO2 SYNDIG1 SMPD3

1.42e-041906241c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCellHealthy_donor-Platelet|World / disease group, cell group and cell class (v2)

GRHL1 H3-3A ABLIM3 F13A1

1.45e-04191624defae87313d6345e3f451250fd66fe8831bb441c
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SDK2 KMT5C PEX5 ABLIM3

1.57e-041956246a0460d949ccda7c9fe76870d3ee6c2f60677d61
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ENTPD7 SDK2 TSPYL2 SMPD3

1.63e-041976243a5908deb5c5a2bf06019a102fb1652233cf2a2a
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

POLR2A SAFB2 RBM5 PRRC2A

1.63e-041976240fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellSepsis-Int-URO-Others-RBC|Int-URO / Disease, condition lineage and cell class

PHKG1 GRHL1 SDK2 SMPD3

1.66e-0419862429203aaa5c1844f72289e03f585cd5e7fc498a9a
ToppCellSepsis-Int-URO-Others|Int-URO / Disease, condition lineage and cell class

PHKG1 GRHL1 SDK2 SMPD3

1.66e-0419862467f721ea8e60042317ba12efd584f56b07cfb29d
ToppCellTransverse-(1)_T_cell-(16)_Tfh|Transverse / shred on region, Cell_type, and subtype

FBXO38 H3C1 KMT5C TSPYL2

1.69e-04199624aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCelldistal-3-mesenchymal-Myofibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PAPPA2 ADAMTS19 ROBO2 SYNDIG1

1.69e-041996241f20addc0d138fec02ed6ca4c518169c568de263
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC12A9 PLA2G4B ELF3 CHD7

1.69e-04199624d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellTransverse-T_cell-Tfh|Transverse / Region, Cell class and subclass

FBXO38 H3C1 KMT5C TSPYL2

1.69e-04199624cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCelldistal-mesenchymal-Myofibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PAPPA2 ADAMTS19 ROBO2 SYNDIG1

1.73e-04200624069c8949b33ecfdb6da32992002d4060ff6082bc
ToppCellCOVID-19-COVID-19_Convalescent-Others-Platelet|COVID-19_Convalescent / Disease, condition lineage and cell class

SH3TC2 GRHL1 ABLIM3 F13A1

1.73e-042006245547e7173293fce403706f69331ce3976da73a32
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related|6m / Sample Type, Dataset, Time_group, and Cell type.

NEU4 H3-3A CHD7 HSD11B2

1.73e-04200624ea1e3eeddbc398ac97863120f7aa3f17569ca12a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related-Oligodendrocyte/OPC|6m / Sample Type, Dataset, Time_group, and Cell type.

NEU4 H3-3A CHD7 HSD11B2

1.73e-042006244a57f2f2dc6e2402ac4772b5cd38e033a6f1adee
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC12A9 PLA2G4B ELF3 CHD7

1.73e-042006248683445ad5b70748c4a1f12eb77d47623085147e
ToppCelldistal-mesenchymal-Myofibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PAPPA2 ADAMTS19 ROBO2 SYNDIG1

1.73e-0420062461854a459385cd9295be37157a8f81a2c227dff3
DiseaseGLIOMA SUSCEPTIBILITY 1

H3C1 H3-3A

6.07e-056602C2750850
Diseaseglucose-dependent insulinotropic peptide measurement, glucose tolerance test

PAPPA2 F13A1

3.64e-0414602EFO_0004307, EFO_0008464
Diseasebrain cancer (implicated_via_orthology)

INSM2 AURKB

1.28e-0326602DOID:1319 (implicated_via_orthology)
Disease17-hydroxyprogesterone measurement

MDC1 PRRC2A

1.59e-0329602EFO_0010220
Diseasecentral nervous system cancer

PAPPA2 POLR2A

1.82e-0331602EFO_0000326

Protein segments in the cluster

PeptideGeneStartEntry
YPYELLLVTTRGRNR

ABLIM3

621

O94929
DRYIAIRIPLRYNGL

ADORA2A

101

P29274
PRLYKIYRERDSERA

ABHD16A

11

O95870
YYKREILERVDGRRL

ELF3

336

P78545
TDALLAARPRRRYYP

HSD11B2

326

P80365
LIQRRYPYERIDGRV

CHD7

1326

Q9P2D1
YPYERIDGRVRGNLR

CHD7

1331

Q9P2D1
LPVYYIREERQRVLL

CFAP251

261

Q8TBY9
LYLLLRRDGRFLAPR

ADAMTS19

176

Q8TE59
RLLRLLPRLDRYSQY

KCNH3

341

Q9ULD8
ELARRLETPYYLVGR

KCNH3

401

Q9ULD8
RERRLLEGYEIYVTP

MDC1

1991

Q14676
LPRDRQYERYLARVG

ENTPD7

56

Q9NQZ7
YGLPYVVRVDLRRLA

KMT5C

396

Q86Y97
RYRPGTVALREIRRY

H3-3A

41

P84243
GRRYRVYPEGTLELR

LRRN2

471

O75325
EDRLRYALVPRYRGL

MLYCD

126

O95822
RYRPGTVALREIRRY

H3-7

41

Q5TEC6
YRPGTVALREIRRYQ

H3-5

41

Q6NXT2
RRALELQPGYIRSRY

PEX5

546

P50542
RPYDPRRDLFRVEYV

F13A1

91

P00488
RRDLFRVEYVIGRYP

F13A1

96

P00488
RYRPGTVALREIRRY

H3-4

41

Q16695
RYRQELAERARLGYP

PLA2G4B

381

P0C869
RYRPGTVALREIRRY

H3C1

41

P68431
LARSYLRRPAVVYIG

DDX23

616

Q9BUQ8
RLLVPAYTYRVDRRE

NEU4

171

Q8WWR8
ARRPYIYSRLEDKGL

SMPD3

91

Q9NY59
LYRVRLAERVFPLLG

INSM2

16

Q96T92
YRDRAAERREKYGIP

RBM5

701

P52756
QLYGLHPRYLERRRV

FBXO38

106

Q6PIJ6
PILYFSGRRERLLLR

PAPPA2

261

Q9BXP8
LGLLYDYYKVPRERR

GRHL1

61

Q9NZI5
VLLIILYGRIYRAAR

HTR1D

211

P28221
RGRQYLLRPGEYRRF

CRYGB

141

P07316
LRERVLRGKYRIPFY

MARK3

261

P27448
GAELVRRPLQLYRYL

LYRM9

6

A8MSI8
LGPYLEFLVLRHRYR

ITIH6

1201

Q6UXX5
YARAERELKPARIYG

ATP5F1C

56

P36542
DEYYRRPLQVLRARE

CST4

61

P01036
GFRIRYRELLYEGLR

SDK2

1536

Q58EX2
YRELLYEGLRGFTLR

SDK2

1541

Q58EX2
KIRELYRRRYPRTLE

PIAS2

56

O75928
YRRRYPRTLEGLSDL

PIAS2

61

O75928
RPLRRLIDAYAFRIY

PHKG1

341

Q16816
TMYLRRPEGIERQYR

STEEP1

76

Q9H5V9
RYRPNIILYSEGVLR

SYNDIG1

86

Q9H7V2
RYRPGTVALREIRRY

H3C15

41

Q71DI3
APRLRRDYSYERVGP

PRRC2A

1006

P48634
RRAIYRIYGDKAPEI

SIN3B

541

O75182
EYYRAGAVPLARRLK

SH3TC2

1106

Q8TF17
GLPRSDVLRIEYLYR

SDHAF1

41

A6NFY7
RYEQERRPAVRRPYD

SAFB

701

Q15424
NYAVRLGRRPTYVEL

CLP1

136

Q92989
DRRRIYLILEYAPRG

AURKB

146

Q96GD4
PLRYYLRERGSRIKR

TSPYL2

391

Q9H2G4
SVRFDRRRGLLYLRP

RNF225

146

M0QZC1
LRIREFYRGRYVLGE

RPAP2

461

Q8IXW5
LRDRIVLGRAYSYPL

TMEM39A

466

Q9NV64
RYQPRIRRSGLELYA

POLR2A

186

P24928
ARYPRYLALLETLTR

SLC12A9

881

Q9BXP2
YPKVFRRGYRRELLI

SLC6A11

426

P48066
PRGRYDIKDDYTLRI

ROBO2

266

Q9HCK4
YEQERRPGRRPYDLD

SAFB2

721

Q14151
RYRLQLRARLNGPTY

MPL

456

P40238
KRYLEGERDAIRYPR

UBR2

1581

Q8IWV8
PSYIRAILRRAELYE

TTC1

186

Q99614