Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	UDP-glucose:glycoprotein glucosyltransferase activity	UGGT1 UGGT2	9.80e-06	2	63	2	GO:0003980
GeneOntologyMolecularFunction	UDP-glucosyltransferase activity	UGGT1 UGGT2	7.47e-04	13	63	2	GO:0035251
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	GLT8D1 GALNT3 UGGT1 UGGT2	1.39e-03	153	63	4	GO:0008194
GeneOntologyMolecularFunction	glycosyltransferase activity	GLT8D1 GALNT3 UGGT1 UGGT2 ALG1	2.14e-03	288	63	5	GO:0016757
GeneOntologyMolecularFunction	glucosyltransferase activity	UGGT1 UGGT2	2.17e-03	22	63	2	GO:0046527
GeneOntologyMolecularFunction	semaphorin receptor binding	SEMA3D SEMA6A	2.37e-03	23	63	2	GO:0030215
GeneOntologyMolecularFunction	histone reader activity	YEATS2 BRD4	3.03e-03	26	63	2	GO:0140566
GeneOntologyBiologicalProcess	UDP-glucosylation	UGGT1 UGGT2	8.60e-06	2	61	2	GO:0097359
GeneOntologyBiologicalProcess	carbohydrate derivative biosynthetic process	ACSL4 EGF GALNT3 ACLY RRM2B UGGT1 MPDU1 HS3ST5 UGGT2 PXYLP1 ALG1	9.10e-06	736	61	11	GO:1901137
GeneOntologyBiologicalProcess	glycoprotein metabolic process	MANBA GALNT3 UGGT1 MPDU1 HS3ST5 UGGT2 PXYLP1 ALG1	3.74e-05	430	61	8	GO:0009100
GeneOntologyBiologicalProcess	carbohydrate derivative metabolic process	ACSL4 MANBA EGF GALNT3 NUDT1 ACLY RRM2B UGGT1 MPDU1 HS3ST5 UGGT2 PXYLP1 ALG1	4.91e-05	1226	61	13	GO:1901135
GeneOntologyBiologicalProcess	protein N-linked glycosylation	UGGT1 MPDU1 UGGT2 ALG1	7.57e-05	76	61	4	GO:0006487
GeneOntologyBiologicalProcess	glycoprotein biosynthetic process	GALNT3 UGGT1 MPDU1 HS3ST5 UGGT2 PXYLP1 ALG1	8.58e-05	357	61	7	GO:0009101
GeneOntologyBiologicalProcess	UDP-alpha-D-glucose metabolic process	UGGT1 UGGT2	1.28e-04	6	61	2	GO:0006011
GeneOntologyBiologicalProcess	sulfur compound biosynthetic process	ACSL4 FMO3 ACLY HS3ST5 PXYLP1	1.82e-04	178	61	5	GO:0044272
GeneOntologyBiologicalProcess	SRP-dependent cotranslational protein targeting to membrane, translocation	TRAM1L1 TRAM1	2.38e-04	8	61	2	GO:0006616
GeneOntologyBiologicalProcess	positive regulation of T-helper 17 cell lineage commitment	BRD2 BRD4	2.38e-04	8	61	2	GO:2000330
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ACSL4 ATP8B3 CLPTM1L FMO3 TRAM1L1 MOGAT1 TRAM1 DHCR24 MPDU1 TRPM8 LRRC8B LRBA ALG1	1.05e-04	1293	63	13	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ACSL4 ATP8B3 CLPTM1L FMO3 TRAM1L1 MOGAT1 TRAM1 DHCR24 MPDU1 TRPM8 LRRC8B LRBA ALG1	1.10e-04	1299	63	13	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	ACSL4 ATP8B3 CLPTM1L FMO3 TRAM1L1 MOGAT1 TRAM1 DHCR24 MPDU1 TRPM8 LRRC8B LRBA ALG1	1.36e-04	1327	63	13	GO:0042175
MousePheno	abnormal kidney morphology	IFIH1 FMO3 MANBA BRD2 GALNT3 NEDD4L RRM2B BRD4 UGGT1 PPIL1 AGXT LGR4 HS3ST5 CXCL14 TNS2 EPB41L4A	6.71e-06	1363	48	16	MP:0002135
MousePheno	abnormal epididymis epithelium morphology	MANBA BRD4 LGR4	3.54e-05	19	48	3	MP:0004933
MousePheno	nephrocalcinosis	GALNT3 BRD4 AGXT	4.16e-05	20	48	3	MP:0003197
MousePheno	small kidney	BRD2 RRM2B UGGT1 PPIL1 LGR4 HS3ST5 CXCL14 TNS2	8.87e-05	425	48	8	MP:0002989
Domain	UDP-g_GGtrans	UGGT1 UGGT2	1.16e-05	2	64	2	IPR009448
Domain	UDP-g_GGTase	UGGT1 UGGT2	1.16e-05	2	64	2	PF06427
Domain	TRAM1	TRAM1L1 TRAM1	3.46e-05	3	64	2	PF08390
Domain	Translocation_assoc_membrane	TRAM1L1 TRAM1	3.46e-05	3	64	2	IPR016447
Domain	TRAM1	TRAM1L1 TRAM1	3.46e-05	3	64	2	IPR013599
Domain	BET	BRD2 BRD4	6.90e-05	4	64	2	PF17035
Domain	NET_dom	BRD2 BRD4	6.90e-05	4	64	2	IPR027353
Domain	NET	BRD2 BRD4	6.90e-05	4	64	2	PS51525
Domain	-	GLT8D1 GALNT3 UGGT1 UGGT2	1.71e-04	81	64	4	3.90.550.10
Domain	Nucleotide-diphossugar_trans	GLT8D1 GALNT3 UGGT1 UGGT2	2.36e-04	88	64	4	IPR029044
Domain	Glyco_transf_8	GLT8D1 UGGT2	5.11e-04	10	64	2	PF01501
Domain	Glyco_trans_8	GLT8D1 UGGT2	5.11e-04	10	64	2	IPR002495
Domain	CRAL_TRIO_N	SEC14L3 SEC14L4	6.23e-04	11	64	2	PF03765
Domain	CRAL-bd_toc_tran	SEC14L3 SEC14L4	7.46e-04	12	64	2	IPR001071
Domain	CRAL_TRIO_N	SEC14L3 SEC14L4	7.46e-04	12	64	2	SM01100
Domain	EMP24_GP25L	SEC14L3 SEC14L4	1.18e-03	15	64	2	PF01105
Domain	CRAL/TRIO_N_dom	SEC14L3 SEC14L4	1.18e-03	15	64	2	IPR011074
Domain	TLC	TRAM1L1 TRAM1	1.34e-03	16	64	2	PS50922
Domain	TLC	TRAM1L1 TRAM1	1.34e-03	16	64	2	SM00724
Domain	TRAM_LAG1_CLN8	TRAM1L1 TRAM1	1.34e-03	16	64	2	PF03798
Domain	TLC-dom	TRAM1L1 TRAM1	1.34e-03	16	64	2	IPR006634
Domain	GOLD_dom	SEC14L3 SEC14L4	1.90e-03	19	64	2	IPR009038
Domain	GOLD	SEC14L3 SEC14L4	1.90e-03	19	64	2	PS50866
Domain	Semaphorin	SEMA3D SEMA6A	2.11e-03	20	64	2	IPR027231
Domain	CRAL_TRIO	SEC14L3 SEC14L4	2.33e-03	21	64	2	PF00650
Domain	-	SEC14L3 SEC14L4	2.79e-03	23	64	2	3.40.525.10
Domain	SEC14	SEC14L3 SEC14L4	3.30e-03	25	64	2	SM00516
Domain	Bromodomain_CS	BRD2 BRD4	3.56e-03	26	64	2	IPR018359
Domain	HECT	NEDD4L HERC6	3.84e-03	27	64	2	PF00632
Domain	HECTc	NEDD4L HERC6	3.84e-03	27	64	2	SM00119
Domain	HECT_dom	NEDD4L HERC6	3.84e-03	27	64	2	IPR000569
Domain	CRAL_TRIO	SEC14L3 SEC14L4	3.84e-03	27	64	2	PS50191
Domain	HECT	NEDD4L HERC6	3.84e-03	27	64	2	PS50237
Domain	CRAL-TRIO_dom	SEC14L3 SEC14L4	4.13e-03	28	64	2	IPR001251
Domain	Sema	SEMA3D SEMA6A	5.04e-03	31	64	2	SM00630
Domain	Semap_dom	SEMA3D SEMA6A	5.04e-03	31	64	2	IPR001627
Domain	Sema	SEMA3D SEMA6A	5.04e-03	31	64	2	PF01403
Domain	SEMA	SEMA3D SEMA6A	5.04e-03	31	64	2	PS51004
Domain	PSI	SEMA3D SEMA6A	5.37e-03	32	64	2	PF01437
Domain	Plexin_repeat	SEMA3D SEMA6A	5.37e-03	32	64	2	IPR002165
Domain	Serpin_dom	SERPINA11 SERPINA9	6.76e-03	36	64	2	IPR023796
Domain	BROMODOMAIN_1	BRD2 BRD4	7.13e-03	37	64	2	PS00633
Domain	SERPIN	SERPINA11 SERPINA9	7.13e-03	37	64	2	SM00093
Domain	SERPIN	SERPINA11 SERPINA9	7.13e-03	37	64	2	PS00284
Domain	Bromodomain	BRD2 BRD4	7.51e-03	38	64	2	PF00439
Domain	Serpin	SERPINA11 SERPINA9	7.51e-03	38	64	2	PF00079
Domain	Serpin_fam	SERPINA11 SERPINA9	7.89e-03	39	64	2	IPR000215
Domain	BROMODOMAIN_2	BRD2 BRD4	8.70e-03	41	64	2	PS50014
Domain	BROMO	BRD2 BRD4	9.11e-03	42	64	2	SM00297
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	ACSL4 CLPTM1L NEDD4L ACLY TRAM1 DHCR24 UGGT1 MPDU1	6.19e-07	392	64	8	33144569
Pubmed	Two homologues encoding human UDP-glucose:glycoprotein glucosyltransferase differ in mRNA expression and enzymatic activity.	UGGT1 UGGT2	3.33e-06	2	64	2	10694380
Pubmed	Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation.	BRD2 BRD4	3.33e-06	2	64	2	32151278
Pubmed	BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.	BRD2 BRD4	3.33e-06	2	64	2	23255218
Pubmed	A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.	BRD2 BRD4	3.33e-06	2	64	2	24146614
Pubmed	Ankyrins, multifunctional proteins involved in many cellular pathways.	ANKRD61 SOWAHB	3.33e-06	2	64	2	12219834
Pubmed	BET bromodomain proteins mediate downstream signaling events following growth factor stimulation in human lung fibroblasts and are involved in bleomycin-induced pulmonary fibrosis.	BRD2 BRD4	3.33e-06	2	64	2	23115324
Pubmed	Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IκB kinase-dependent NF-κB activation in rheumatoid fibroblast-like synoviocytes.	BRD2 BRD4	3.33e-06	2	64	2	26324948
Pubmed	Progesterone regulates the expression and activity of two mouse isoforms of the glycoprotein folding sensor UDP-Glc: glycoprotein glucosyltransferase (UGGT).	UGGT1 UGGT2	3.33e-06	2	64	2	24140206
Pubmed	Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2.	BRD2 BRD4	3.33e-06	2	64	2	35839775
Pubmed	Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2.	UGGT1 UGGT2	3.33e-06	2	64	2	33320095
Pubmed	Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specification.	BRD2 BRD4	3.33e-06	2	64	2	28588073
Pubmed	Effects of domain composition on catalytic activity of human UDP-glucose:glycoprotein glucosyltransferases.	UGGT1 UGGT2	3.33e-06	2	64	2	27496766
Pubmed	Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes.	BRD2 BRD4	3.33e-06	2	64	2	16940503
Pubmed	WHAT do viruses BET on?	BRD2 BRD4	3.33e-06	2	64	2	20036832
Pubmed	The noncatalytic portion of human UDP-glucose: glycoprotein glucosyltransferase I confers UDP-glucose binding and transferase function to the catalytic domain.	UGGT1 UGGT2	3.33e-06	2	64	2	12913004
Pubmed	Both isoforms of human UDP-glucose:glycoprotein glucosyltransferase are enzymatically active.	UGGT1 UGGT2	3.33e-06	2	64	2	24415556
Pubmed	SARS-CoV-2 E protein interacts with BRD2 and BRD4 SEED domains and alters transcription in a different way than BET inhibition.	BRD2 BRD4	3.33e-06	2	64	2	39066826
Pubmed	Interplay between Porphyromonas gingivalis and EGF signalling in the regulation of CXCL14.	EGF CXCL14	9.99e-06	3	64	2	29504253
Pubmed	Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system.	BRD2 BRD4	9.99e-06	3	64	2	31792058
Pubmed	NF-κB signaling activation via increases in BRD2 and BRD4 confers resistance to the bromodomain inhibitor I-BET151 in U937 cells.	BRD2 BRD4	9.99e-06	3	64	2	30300821
Pubmed	Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.	BRD2 BRD4	9.99e-06	3	64	2	28262505
Pubmed	Rat supernatant protein factor-like protein stimulates squalene monooxygenase and is activated by protein kinase A.	SEC14L3 SEC14L4	9.99e-06	3	64	2	15033454
Pubmed	Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.	BRD2 BRD4	9.99e-06	3	64	2	25049379
Pubmed	Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration.	BRD2 BRD4	9.99e-06	3	64	2	24049186
Pubmed	Association between the 15-kDa selenoprotein and UDP-glucose:glycoprotein glucosyltransferase in the endoplasmic reticulum of mammalian cells.	UGGT1 UGGT2	9.99e-06	3	64	2	11278576
Pubmed	BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-Mesenchymal Transition.	BRD2 BRD4	9.99e-06	3	64	2	29437854
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CLPTM1L GLT8D1 MANBA GALNT3 NEDD4L ACLY TRAM1 UGGT1 LGR4 UGGT2 ALG1	1.10e-05	1201	64	11	35696571
Pubmed	LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.	BRD2 BRD4	2.00e-05	4	64	2	31504794
Pubmed	Expression of BET genes in testis of men with different spermatogenic impairments.	BRD2 BRD4	2.00e-05	4	64	2	22035730
Pubmed	Cloning of novel human SEC14p-like proteins: ligand binding and functional properties.	SEC14L3 SEC14L4	2.00e-05	4	64	2	12757856
Pubmed	The ankyrin repeat: a diversity of interactions on a common structural framework.	ANKRD61 SOWAHB	2.00e-05	4	64	2	10431175
Pubmed	Ankyrin repeat: a unique motif mediating protein-protein interactions.	ANKRD61 SOWAHB	2.00e-05	4	64	2	17176038
Pubmed	The ankyrin repeat as molecular architecture for protein recognition.	ANKRD61 SOWAHB	2.00e-05	4	64	2	15152081
Pubmed	Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.	BRD2 BRD4	2.00e-05	4	64	2	24248598
Pubmed	Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors.	BRD2 BRD4	2.00e-05	4	64	2	22912406
Pubmed	Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.	BRD2 BRD4	3.32e-05	5	64	2	24733848
Pubmed	NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor.	NEDD4L LGR4	3.32e-05	5	64	2	31867777
Pubmed	Intron 1-Mediated Regulation of EGFR Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins.	BRD2 BRD4	4.98e-05	6	64	2	31444232
Pubmed	Defining the membrane proteome of NK cells.	ACSL4 CLPTM1L GLT8D1 ACLY DHCR24 MPDU1 LRBA CTSW ALG1 STEAP1	5.12e-05	1168	64	10	19946888
Pubmed	Multiomics analysis reveals that hepatocyte nuclear factor 1β regulates axon guidance genes in the developing mouse kidney.	SEMA3D SEMA6A	6.96e-05	7	64	2	36266461
Pubmed	Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.	ACSL4 CLPTM1L NEDD4L DHCR24 UGGT1	7.44e-05	235	64	5	32614325
Pubmed	BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail.	BRD2 BRD4	9.27e-05	8	64	2	31311807
Pubmed	The SARS-CoV-2 spike protein binds and modulates estrogen receptors.	PPIL1 EPB41L4A	1.19e-04	9	64	2	36449624
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	IFIH1 CLPTM1L NEDD4L CDKN2AIP UGGT1	1.77e-04	283	64	5	21903422
Pubmed	Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.	BRD2 BRD4	1.81e-04	11	64	2	28805820
Pubmed	Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabine-treated non-small-cell lung cancer patients.	EGF RRM2B	2.17e-04	12	64	2	16407418
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	CLPTM1L NEDD4L TRAM1 UGGT1 MPDU1 UGGT2	2.23e-04	468	64	6	31056421
Pubmed	A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.	TRAM1L1 MANBA EGF	2.29e-04	64	64	3	20332099
Pubmed	BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos.	BRD2 BRD4	2.57e-04	13	64	2	35264162
Pubmed	Getting in and out from calnexin/calreticulin cycles.	UGGT1 UGGT2	2.57e-04	13	64	2	18303019
Pubmed	TRF2-mediated telomere protection is dispensable in pluripotent stem cells.	BRD2 PPIL1	2.99e-04	14	64	2	33239785
Pubmed	Defining brain wiring patterns and mechanisms through gene trapping in mice.	LGR4 SEMA6A	2.99e-04	14	64	2	11242070
Pubmed	Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.	GLT8D1 NUDT1 ACLY TRAM1 DHCR24 UGGT1 TNS2 ALG1	3.01e-04	931	64	8	27432908
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	SEMA3D SEMA6A	3.93e-04	16	64	2	22632726
Pubmed	Balance between BDNF and Semaphorins gates the innervation of the mammary gland.	SEMA3D SEMA6A	3.93e-04	16	64	2	30628891
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	SEMA3D GLT8D1 PPIL1 CXCL14 PXYLP1 LRRC8B SERPINA9 ALG1	4.38e-04	985	64	8	12975309
Pubmed	Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers.	UGGT1 ALG1	4.45e-04	17	64	2	32938586
Pubmed	Histone crosstalk between H3S10ph and H4K16ac generates a histone code that mediates transcription elongation.	BRD2 BRD4	5.59e-04	19	64	2	19766566
Pubmed	A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.	NEDD4L ACLY UBE2C	5.83e-04	88	64	3	27182664
Pubmed	Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1.	SERPINA11 SERPINA9	6.84e-04	21	64	2	15014966
Pubmed	Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.	NUDT1 ACLY DHCR24	6.85e-04	93	64	3	27689697
Pubmed	IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.	MPDU1 UBE2C PPIL1 LRBA	7.48e-04	221	64	4	31950832
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	YEATS2 CRNKL1 BRD2 BRD4	7.61e-04	222	64	4	37071664
Pubmed	Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.	GALNT3 LGR4	8.23e-04	23	64	2	24945404
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	SEMA3D SEMA6A	8.96e-04	24	64	2	15869472
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	CRNKL1 BRD2 BRD4	9.22e-04	103	64	3	32744500
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	YEATS2 BRD2 CDKN2AIP BRD4 PPIL1	9.68e-04	411	64	5	35182466
Pubmed	Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.	GLT8D1 MANBA	9.73e-04	25	64	2	2283726
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	NEDD4L HERC6	1.05e-03	26	64	2	26949039
Pubmed	Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.	GLT8D1 MANBA	1.05e-03	26	64	2	8218172
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ACSL4 YEATS2 CLPTM1L GALNT3 MPDU1 HERC6	1.13e-03	638	64	6	31182584
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	SEMA3D SEMA6A	1.22e-03	28	64	2	18617019
Pubmed	Biosynthesis of triacylglycerols.	ACSL4 ACLY	1.22e-03	28	64	2	8944226
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	ACSL4 CRNKL1 ACLY TRAM1 BRD4 UGGT1 UGGT2 EPB41L4A ALG1	1.30e-03	1451	64	9	30550785
Pubmed	Identification of cathepsin K as a novel marker of adiposity in white adipose tissue.	ATP8B3 CLPTM1L	1.31e-03	29	64	2	12652657
Pubmed	The DNA sequence of human chromosome 7.	DOCK4 SEMA3D SAMD9 ANKRD61 STEAP1	1.32e-03	441	64	5	12853948
Pubmed	Cryo-EM structure of a human spliceosome activated for step 2 of splicing.	CRNKL1 PPIL1	1.40e-03	30	64	2	28076346
Pubmed	Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP.	CDKN2AIP PPIL1	1.40e-03	30	64	2	37019383
Pubmed	The mutational constraint spectrum quantified from variation in 141,456 humans.	COL6A5 SEC14L4	1.60e-03	32	64	2	32461654
Pubmed	Common homozygosity for predicted loss-of-function variants reveals both redundant and advantageous effects of dispensable human genes.	COL6A5 SEC14L4	1.60e-03	32	64	2	32487729
Pubmed	Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.	DOCK4 EGF	1.70e-03	33	64	2	18271526
Pubmed	TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.	NEDD4L BRD4	1.70e-03	33	64	2	33567268
Cytoband	14q32.13	SERPINA11 SERPINA9	2.57e-04	17	64	2	14q32.13
Cytoband	7p22	NUDT1 ANKRD61	3.58e-04	20	64	2	7p22
Cytoband	Ensembl 112 genes in cytogenetic band chr7q21	SEMA3D SAMD9 STEAP1	2.01e-03	178	64	3	chr7q21
GeneFamily	UDP-glucose glycoprotein glucosyltransferases	UGGT1 UGGT2	6.33e-06	2	46	2	440
GeneFamily	SEC14 family\|PRELI domain containing	SEC14L3 SEC14L4	9.44e-05	6	46	2	1063
GeneFamily	TLC domain containing	TRAM1L1 TRAM1	2.81e-04	10	46	2	1374
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA3D SEMA6A	1.17e-03	20	46	2	736
GeneFamily	Serpin peptidase inhibitors	SERPINA11 SERPINA9	3.99e-03	37	46	2	739
Coexpression	GSE30083_SP1_VS_SP4_THYMOCYTE_DN	IFIH1 MANBA RRM2B PXYLP1 HERC6 CTSW	9.50e-06	200	64	6	M5030
Coexpression	DESCARTES_FETAL_LIVER_ERYTHROBLASTS	SEC14L3 ANKRD61 SEC14L4 RHCE	4.03e-05	78	64	4	M40235
Coexpression	GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_UP	IFIH1 NEDD4L WDR97 TNS2 HERC6	1.08e-04	192	64	5	M9509
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL	SEC14L3 IFIH1 SEMA3D AGXT CXCL14	1.10e-04	193	64	5	M6813
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL	SEC14L3 IFIH1 SEMA3D AGXT CXCL14	1.18e-04	196	64	5	MM667
Coexpression	GSE3982_MAST_CELL_VS_NEUTROPHIL_DN	IFIH1 SAMD9 CXCL14 SEMA6A BTN3A1	1.21e-04	197	64	5	M5433
Coexpression	GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN	IFIH1 YEATS2 SAMD9 HERC6 BTN3A1	1.24e-04	198	64	5	M8969
Coexpression	GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN	IFIH1 SAMD9 GALNT3 SEMA6A HERC6	1.24e-04	198	64	5	M4272
Coexpression	GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP	IFIH1 YEATS2 SAMD9 SEMA6A HERC6	1.30e-04	200	64	5	M8972
Coexpression	GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN	IFIH1 YEATS2 SAMD9 HERC6 BTN3A1	1.30e-04	200	64	5	M8967
Coexpression	GSE30083_SP1_VS_SP3_THYMOCYTE_DN	IFIH1 RRM2B PXYLP1 HERC6 CTSW	1.30e-04	200	64	5	M5026
Coexpression	BLANCO_MELO_HUMAN_PARAINFLUENZA_VIRUS_3_INFECTION_A594_CELLS_UP	IFIH1 SEMA3D SAMD9 HERC6 BTN3A1	1.43e-04	204	64	5	M34006
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	ACSL4 EGF NEDD4L LGR4 LRBA	1.56e-04	208	64	5	M39233
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUDT1 UBE2C PPIL1 PXYLP1 CTSW	4.89e-06	172	64	5	dd9ba79e1542fe9fa2c319077d83dd3fc0158f46
ToppCell	Mild_COVID-19\|World / Disease group,lineage and cell class （2021.01.30）	IFIH1 SAMD9 HERC6 BTN3A1 CTSW	8.56e-06	193	64	5	325b0768827bf8701bfb7f686bb11fd8b1a41a5c
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast\|World / Lineage, cell class and subclass	UBE2C PPIL1 SEC14L4 RHCE CA3	8.78e-06	194	64	5	008bb0072f414a48d052429101bdc990ee4f80c2
ToppCell	Mild\|World / Disease group and Cell class	IFIH1 SAMD9 HERC6 BTN3A1 CTSW	9.23e-06	196	64	5	5e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	IFIH1 SAMD9 HERC6 BTN3A1 CTSW	9.23e-06	196	64	5	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	saliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FMO3 GALNT3 DHCR24 LGR4 STEAP1	9.46e-06	197	64	5	d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCell	saliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FMO3 GALNT3 DHCR24 LGR4 STEAP1	9.46e-06	197	64	5	80b05c8ad9c1edc5dea3236079372475431343fe
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ATP8B3 CXCL14 EPB41L4A STEAP1	1.37e-05	101	64	4	6523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ATP8B3 CXCL14 EPB41L4A STEAP1	1.48e-05	103	64	4	d8965b338b90ddc0686ea0d94e9a330128566c39
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Slc17a8\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ATP8B3 CXCL14 EPB41L4A CA3	2.61e-05	119	64	4	6435891e6e33e7ae07e0c3a64a66edfbeedb54be
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ATP8B3 CXCL14 EPB41L4A CA3	5.22e-05	142	64	4	ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCell	IIH-CD4-antiviral_CD4\|IIH / Condition, Cell_class and T cell subcluster	IFIH1 SEMA3D HERC6 SEC14L4	6.13e-05	148	64	4	ec626a44cea83f2a0e5c27fc8182f96446d297ac
ToppCell	droplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	6.62e-05	151	64	4	cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell	droplet-Liver-nan-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	6.62e-05	151	64	4	7758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCell	droplet-Liver-nan-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	6.62e-05	151	64	4	b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCell	droplet-Liver-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	6.80e-05	152	64	4	1febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCell	droplet-Liver-nan-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	6.80e-05	152	64	4	faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	8.29e-05	160	64	4	8de1fc75241d9bf2b355afa0e9ef39fea1977177
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	8.49e-05	161	64	4	274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	8.91e-05	163	64	4	03d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	8.91e-05	163	64	4	1c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCell	droplet-Liver-Hepatocytes-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 DHCR24 AGXT CA3	8.91e-05	163	64	4	7e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO3 AGXT SEC14L4 CA3	9.12e-05	164	64	4	90afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCell	COVID-19_Severe-CD4+_T_activated\|COVID-19_Severe / Disease condition and Cell class	IFIH1 SAMD9 ANKRD61 HERC6	9.56e-05	166	64	4	0f138dbafad6f83975944e8f6398411127b150cc
ToppCell	facs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINA11 CXCL14 SEC14L4 CA3	9.78e-05	167	64	4	3e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCell	facs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINA11 CXCL14 SEC14L4 CA3	9.78e-05	167	64	4	3ad9f3122dbe96580f640388ef920ea209fc2349
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	YEATS2 PRTG UBE2C CXCL14	1.00e-04	168	64	4	53a982869dbf14f6a948589be9f2f3df3b9a7e97
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SEC14L3 SEC14L4 RHCE CA3	1.00e-04	168	64	4	360cd756067c8cfb6a78301674758eb5fac52c23
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SEC14L3 SEC14L4 RHCE CA3	1.00e-04	168	64	4	d791116040a9d3ea0485d68c974340116073986b
ToppCell	TCGA-Colorectal-Recurrent_Tumor\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SERPINA11 FMO3 AGXT TRPM8	1.17e-04	175	64	4	7f74961436f88c0e380819095e6104489914d765
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IFIH1 SAMD9 HERC6 BTN3A1	1.17e-04	175	64	4	97616bb5c127284aa9e67bc336dfcf29e137164b
ToppCell	TCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SERPINA11 FMO3 AGXT TRPM8	1.17e-04	175	64	4	bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	IFIH1 YEATS2 SAMD9 HERC6	1.28e-04	179	64	4	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CXCL14 SEC14L4 RHCE CA3	1.28e-04	179	64	4	dfefa4b7ae0ee50cf67e0f1938c682f08a03ec53
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CXCL14 SEC14L4 RHCE CA3	1.28e-04	179	64	4	64672528f73ac0921f9c7df72e14ecbfac4d5270
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEDD4L DHCR24 LRBA EPB41L4A	1.28e-04	179	64	4	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CXCL14 SEC14L4 RHCE CA3	1.28e-04	179	64	4	fa0dd87111d399649cdea55f2e610ebc169e8a56
ToppCell	facs-SCAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFIH1 CXCL14 STEAP1 CA3	1.31e-04	180	64	4	6c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PRTG HS3ST5 PXYLP1 LRBA	1.31e-04	180	64	4	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	YEATS2 SEMA3D DHCR24 PPIL1	1.39e-04	183	64	4	fef51dcf180e6d4e136362c7e140ec5ef372e6d0
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 ACSL4 SEMA6A EPB41L4A	1.42e-04	184	64	4	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	PRTG EGF NEDD4L DHCR24	1.42e-04	184	64	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	PND01-03-samps-Epithelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SEC14L3 ACSL4 NEDD4L SEC14L4	1.45e-04	185	64	4	2b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	BRD2 NEDD4L CDKN2AIP CXCL14	1.48e-04	186	64	4	35f32fc2761435356c8f54b5bb2f026b8c070efe
ToppCell	droplet-Tongue-nan-24m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHCR24 LGR4 SEMA6A SOWAHB	1.48e-04	186	64	4	18c06041c6c8a0ebac17b3c8aaebd67e652d315a
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SERPINA11 AGXT RHCE CA3	1.51e-04	187	64	4	edb0ab0154542b1c0b3a2c216c4a60f0f06290b3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRTG NEDD4L CXCL14 CTSW	1.51e-04	187	64	4	b426a67b5669019115b58295ce7d304beeb75825
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SEC14L3 ACSL4 NEDD4L SEC14L4	1.51e-04	187	64	4	23fe3cdd6cc9b067086a8392d104186d300298ea
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	NEDD4L DHCR24 LGR4 EPB41L4A	1.51e-04	187	64	4	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	IFIH1 YEATS2 SAMD9 HERC6	1.54e-04	188	64	4	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.54e-04	188	64	4	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.54e-04	188	64	4	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK4 SEMA3D SEMA6A EPB41L4A	1.57e-04	189	64	4	c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.57e-04	189	64	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.57e-04	189	64	4	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.57e-04	189	64	4	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.57e-04	189	64	4	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SERPINA11 AGXT RHCE CA3	1.57e-04	189	64	4	7899af78b273d9c7f029d52f7e0cf6df4da41f5e
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SERPINA11 AGXT RHCE CA3	1.61e-04	190	64	4	a34293601aefe5fb5c400c14091294b9ddaa195b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.61e-04	190	64	4	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 EGF LGR4 LRBA	1.61e-04	190	64	4	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK4 SEMA3D SEMA6A EPB41L4A	1.61e-04	190	64	4	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.61e-04	190	64	4	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	Calu_3-infected-SARSCoV2\|infected / Cell line, Condition and Strain	IFIH1 SAMD9 HERC6 BTN3A1	1.64e-04	191	64	4	2da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NEDD4L HS3ST5 EPB41L4A CA3	1.64e-04	191	64	4	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	COVID-19_Severe-CD8+_T_activated\|World / disease group, cell group and cell class	SAMD9 HERC6 EPB41L4A CTSW	1.71e-04	193	64	4	ddc1db516568e03be8e82b2ca770c67756418185
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	NEDD4L HS3ST5 EPB41L4A CA3	1.71e-04	193	64	4	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 NEDD4L SEMA6A EPB41L4A	1.71e-04	193	64	4	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHCR24 LGR4 SEMA6A SOWAHB	1.71e-04	193	64	4	55eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	DOCK4 FMO3 COL6A5 CA3	1.71e-04	193	64	4	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	moderate-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	IFIH1 SEMA3D SAMD9 HERC6	1.71e-04	193	64	4	22455801194bd8c73c5c397f5eac4f723429c383
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EGF NEDD4L LGR4 LRBA	1.74e-04	194	64	4	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	PBMC-Mild\|PBMC / Compartment, Disease Groups and Clusters	IFIH1 SAMD9 BRD2 HERC6	1.74e-04	194	64	4	d1366b169d14011194e61d16b6b0953349febc78
ToppCell	368C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 FMO3 COL6A5 CA3	1.74e-04	194	64	4	d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell	control-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IFIH1 SAMD9 HERC6 BTN3A1	1.74e-04	194	64	4	267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCell	368C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 FMO3 COL6A5 CA3	1.74e-04	194	64	4	e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DHCR24 UBE2C PPIL1 CTSW	1.77e-04	195	64	4	be8db0a22ef8ce24819f790b0bd93670e73af76f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EGF NEDD4L LGR4 LRBA	1.77e-04	195	64	4	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSL4 EGF LGR4 LRBA	1.77e-04	195	64	4	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	BAL-Mild\|BAL / Location, Disease Group, Cell group, Cell class (2021.03.09)	SAMD9 HERC6 BTN3A1 CTSW	1.81e-04	196	64	4	6566e6671257f7df4d3f375e84f0b292ab4bcde1
ToppCell	BAL-Mild\|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SAMD9 HERC6 BTN3A1 CTSW	1.81e-04	196	64	4	3408d561d29802fca9eff5c54ccf70818d240cea
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACSL4 PRTG NEDD4L DHCR24	1.81e-04	196	64	4	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	CV-Moderate-1\|Moderate / Virus stimulation, Condition and Cluster	IFIH1 SAMD9 HERC6 CTSW	1.81e-04	196	64	4	b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CRNKL1 GALNT3 BTN3A1 CTSW	1.81e-04	196	64	4	c57a95f8b4d8d6334f269d3c16246684f4222a3e
ToppCell	Enterocyte-C_05\|Enterocyte / shred on cell type and cluster	IFIH1 SAMD9 NXPE1 HERC6	1.81e-04	196	64	4	c307e5a70186567c62da938caa21749dc0e929d0
ToppCell	severe-T/NK_proliferative\|severe / disease stage, cell group and cell class	NUDT1 DHCR24 UBE2C PPIL1	1.81e-04	196	64	4	89f005216770dbb84378f5d1f20ca11b0ce40faa
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EGF NEDD4L LGR4 LRBA	1.81e-04	196	64	4	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	CV-Moderate-1\|CV / Virus stimulation, Condition and Cluster	IFIH1 SAMD9 HERC6 CTSW	1.84e-04	197	64	4	e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ToppCell	severe-T/NK_proliferative\|World / disease stage, cell group and cell class	NUDT1 DHCR24 UBE2C PPIL1	1.84e-04	197	64	4	6b7b068b103fd4f6ceda8e01f4dd39eefc3b3633
ToppCell	COVID-19_Moderate-CD8+_T_activated\|COVID-19_Moderate / disease group, cell group and cell class	SAMD9 HERC6 EPB41L4A CTSW	1.84e-04	197	64	4	4711ecb157e907758a5021248ae8b043d17672c6
ToppCell	CD8+_Memory_T_cell-CV-1\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	IFIH1 SAMD9 HERC6 CTSW	1.84e-04	197	64	4	e59b47bccc781b2117196fe322efa87559c237c6
ToppCell	erythropoietic-Polychromatic_Erythroblast\|World / Lineage and Cell class	PPIL1 SEC14L4 RHCE CA3	1.84e-04	197	64	4	604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	DOCK4 FMO3 COL6A5 CA3	1.84e-04	197	64	4	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	CV-Severe-1\|Severe / Virus stimulation, Condition and Cluster	IFIH1 SAMD9 HERC6 CTSW	1.88e-04	198	64	4	9b9ee0b0f6cc92e7be94869604c98f43d57ff8ff
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L HS3ST5 EPB41L4A CA3	1.88e-04	198	64	4	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	CV-Severe-1\|CV / Virus stimulation, Condition and Cluster	IFIH1 SAMD9 HERC6 CTSW	1.88e-04	198	64	4	fc0e885e370ffb780eada62bb2b52065c2f8b26b
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEDD4L DHCR24 HS3ST5 EPB41L4A	1.88e-04	198	64	4	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEDD4L HS3ST5 EPB41L4A CA3	1.88e-04	198	64	4	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	CV-Mild-1\|CV / Virus stimulation, Condition and Cluster	IFIH1 SAMD9 HERC6 CTSW	1.88e-04	198	64	4	4b078714c49e7befb7b113d72485e712236d35fa
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IFIH1 SAMD9 BRD2 HERC6	1.92e-04	199	64	4	d3f36ede2fade550ec8f21a0448e71e1ff579ee2
Disease	serpin A9 measurement	SERPINA11 SERPINA9	2.43e-05	4	60	2	EFO_0802062
Disease	kallistatin measurement	SERPINA11 SERPINA9	1.13e-04	8	60	2	EFO_0008196
Disease	Influenza	IFIH1 SAMD9 HERC6	1.65e-04	52	60	3	C0021400
Disease	papillary thyroid carcinoma	PCNX2 SOWAHB	2.65e-04	12	60	2	EFO_0000641
Disease	Glioblastoma	BRD2 EGF BRD4	5.66e-04	79	60	3	C0017636
Disease	ulcerative colitis	SEC14L3 IFIH1 TRAM1L1 BRD2 NXPE1	6.00e-04	335	60	5	EFO_0000729
Disease	Giant Cell Glioblastoma	BRD2 EGF BRD4	6.77e-04	84	60	3	C0334588
Disease	gamma-glutamylglutamine measurement	MANBA EPB41L4A	9.15e-04	22	60	2	EFO_0021138
Disease	alpha fetoprotein measurement	SERPINA11 MANBA SERPINA9	1.12e-03	100	60	3	EFO_0010583
Disease	preterm premature rupture of the membranes, spontaneous preterm birth	GALNT3 LGR4	1.49e-03	28	60	2	EFO_0006917, MONDO_0012511
Disease	Glioblastoma Multiforme	BRD2 EGF BRD4	1.52e-03	111	60	3	C1621958
Disease	Prostatic Neoplasms	ACSL4 CLPTM1L SAMD9 EGF GALNT3 BRD4	1.56e-03	616	60	6	C0033578
Disease	Malignant neoplasm of prostate	ACSL4 CLPTM1L SAMD9 EGF GALNT3 BRD4	1.56e-03	616	60	6	C0376358

Protein segments in the cluster

Peptide	Gene	Start	Entry
IFIPWYFLTNAKKKN	ACSL4	26	O60488
VHWNPKYNTFKEALK	CA3	121	P07451
SYWFPLLLQKKKFHG	NUDT1	121	P36639
NHPLVLLAKWYEKFF	ALG1	171	Q9BT22
HSAYNEWKKALFKPA	BTN3A1	326	O00481
AKKHAAYAWPFYKPV	BRD4	366	O60885
KYKQHLKQFLPVTIW	ANKRD61	391	A6NGH8
PYLWNKFADGKLLFH	ATP8B3	531	O60423
KNWTLWKHFKDYFPI	MOGAT1	76	Q96PD6
WKHFKDYFPIHLIKT	MOGAT1	81	Q96PD6
QKPCFFFHWLKLFAI	FMO3	506	P31513
KQPFFNRLYKTVAWK	CDKN2AIP	436	Q9NXV6
KHLERWLKYFPIEQF	HS3ST5	236	Q8IZT8
LLKSLQPFAKWHYIE	PCNX2	1556	A6NKB5
YQKSHPTIQLFWKAF	HERC6	921	Q8IVU3
FQHCVKFDFKPQKWY	LRBA	286	P50851
YVFFNPKFKEDWKLL	LGR4	801	Q9BXB1
YSPQFVKAAKLLHWN	GLT8D1	316	Q68CQ7
HPKLQSTKRFIKWYN	CXCL14	86	O95715
EKQLHWFAKFFPYLV	LRRC8B	111	Q6P9F7
YGPIIKNNSKKKWFF	PRTG	1041	Q2VWP7
PHKKFTFAKMWILYA	CRNKL1	566	Q9BZJ0
PDNIKSFYKVNHIWK	DOCK4	1401	Q8N1I0
PVENKIYFAHTALKW	EGF	521	P01133
YHKKFWKLGAVIFFF	GALNT3	16	Q14435
KPWFFKHVENYLKTN	DHCR24	301	Q15392
DWNYIIKFVKPFVHL	COL6A5	2476	A8TX70
QLFRKEFQPFLKKWY	IFIH1	371	Q9BYX4
CHPKKYQKVAWIQDF	CTSW	226	P56202
KWKMLHYFAQNFFAP	MANBA	676	O00462
KYFWPRITKVHFKET	EPB41L4A	241	Q9HCS5
KHFWKPLVEVYQEFF	SEC14L3	161	Q9UDX4
KHLWKPAVEVYQQFF	SEC14L4	161	Q9UDX3
PWNVFDGKLFHQKYL	FAM120B	801	Q96EK7
IQWKKHSYPFVTFQL	NXPE1	396	Q8N323
KPFSFYLDIKWLANF	AGXT	236	P21549
HFYIKKKDFGNALNW	SAMD9	1091	Q5K651
FLPDFDWKKIYFRHQ	PXYLP1	221	Q8TE99
DWKKIYFRHQPSALF	PXYLP1	226	Q8TE99
NKWKLANQYEKFHSP	SOWAHB	771	A6NEL2
LLFYWNAKPPHKQKK	MPDU1	231	O75352
IFFKAKWEKPFHPEY	SERPINA9	206	Q86WD7
VDLNKNFKKIYWPAA	SEMA3D	96	O95025
LHNGTKYKKFPHWLD	STEAP1	141	Q9UHE8
FYWGHKEILIPVFKN	ACLY	541	P53396
NPFALYWLSKSFQKH	BRS3	326	P32247
LSKKHAAYAWPFYKP	BRD2	361	P25440
YKLKSVAHLPWKAFT	CLPTM1L	456	Q96KA5
PHWNKLKADEKYFIS	RRM2B	76	Q7LG56
WFHAFPELYFQKTKK	TRAM1L1	176	Q8N609
KIWKAPHVAKYFDDQ	RHCE	391	P18577
ELYWKHAPKTCKNFA	PPIL1	26	Q9Y3C6
VLANYIFFKAKWKHP	SERPINA11	206	Q86U17
IFFKAKWKHPFSRYQ	SERPINA11	211	Q86U17
HPFFFWLKLKINKVM	TAS2R9	116	Q9NYW1
PKFLHFFIYQTWFKK	WDR97	1176	A6NE52
KHDSKWLKEPYFVQA	SEMA6A	211	Q9H2E6
KAFKWYGSFVQHQKL	ZNF621	326	Q6ZSS3
WLHAFPELYFQKTKK	TRAM1	176	Q15629
HDVKQKFHKACPKWY	TECRL	86	Q5HYJ1
PVDKHKKLLWYYVAF	TRPM8	716	Q7Z2W7
VKFWLLKNYLSPTFK	UGGT2	1261	Q9NYU1
KFVQDTSKFWYKPHL	TNS2	1131	Q63HR2
NTKTPVKFWFLKNYL	UGGT1	1281	Q9NYU2
VKFWFLKNYLSPTFK	UGGT1	1286	Q9NYU2
VKKVWFFLHPSYKPN	YEATS2	251	Q9ULM3
HAAELWKNPTAFKKY	UBE2C	151	O00762
IKKTLNPKWNEEFYF	NEDD4L	66	Q96PU5