Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

NCOR1 RELN MTOR NTRK3 ROR2 HLA-G OBSCN RAPGEF1 DLG1 IRS1

5.80e-073347910GO:0051896
GeneOntologyBiologicalProcessphosphatidylinositol 3-kinase/protein kinase B signal transduction

NCOR1 RELN MTOR NTRK3 ROR2 HLA-G OBSCN RAPGEF1 DLG1 IRS1

1.95e-063827910GO:0043491
GeneOntologyBiologicalProcessnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

NCOR1 HLA-G OBSCN RAPGEF1 DLG1

1.98e-0586795GO:0051898
GeneOntologyBiologicalProcessregulatory T cell differentiation

NCOR1 CARMIL2 DROSHA HLA-G

5.45e-0554794GO:0045066
GeneOntologyBiologicalProcesscell junction organization

RELN CCM2 HMCN2 ABCC8 NTRK3 NCAN UBE3B ROR2 RAPGEF1 DLG1 DIXDC1 CLSTN1 UNC13A

7.81e-059747913GO:0034330
GeneOntologyBiologicalProcessregulation of relaxation of smooth muscle

GRK2 ABCC8

8.65e-054792GO:1901080
DomainPP2A_PR55

PPP2R2B PPP2R2C

1.11e-044812IPR000009
DomainPP2A_PR55_CS

PPP2R2B PPP2R2C

1.11e-044812IPR018067
DomainDUF4195

ZNF280D ZNF280C

1.11e-044812PF13836
DomainDUF4195

ZNF280D ZNF280C

1.11e-044812IPR025243
DomainPR55_2

PPP2R2B PPP2R2C

1.11e-044812PS01025
DomainPR55_1

PPP2R2B PPP2R2C

1.11e-044812PS01024
DomainIg_I-set

UNC5A HMCN2 NTRK3 ROR2 OBSCN CDON

1.77e-04190816IPR013098
DomainI-set

UNC5A HMCN2 NTRK3 ROR2 OBSCN CDON

1.77e-04190816PF07679
DomainFATC

ATR MTOR

1.84e-045812PF02260
DomainFAT

ATR MTOR

2.76e-046812PS51189
DomainFATC

ATR MTOR

2.76e-046812PS51190
DomainFAT

ATR MTOR

2.76e-046812PF02259
DomainPIK-rel_kinase_FAT

ATR MTOR

2.76e-046812IPR003151
DomainFATC_dom

ATR MTOR

2.76e-046812IPR003152
DomainPIK_FAT

ATR MTOR

2.76e-046812IPR014009
DomainFATC

ATR MTOR

2.76e-046812SM01343
DomainWD40_repeat_dom

PPP2R2B PPP2R2C BCAS3 WDR81 NOL11 BBS2 RIC1

3.05e-04297817IPR017986
DomainKinase-like_dom

PLK2 GRK2 ATR MTOR NTRK3 ROR2 OBSCN WDR81 MAP3K15

5.57e-04542819IPR011009
Domain-

PPP2R2B PPP2R2C BCAS3 WDR81 NOL11 BBS2 RIC1

6.04e-043338172.130.10.10
DomainWD40/YVTN_repeat-like_dom

PPP2R2B PPP2R2C BCAS3 WDR81 NOL11 BBS2 RIC1

6.26e-04335817IPR015943
DomainIG_LIKE

UNC5A HMCN2 NTRK3 NCAN ROR2 HLA-G OBSCN CDON

1.29e-03491818PS50835
DomainIg-like_dom

UNC5A HMCN2 NTRK3 NCAN ROR2 HLA-G OBSCN CDON

1.50e-03503818IPR007110
DomainPI3/4_kinase_CS

ATR MTOR

1.88e-0315812IPR018936
Domain-

ATR MTOR

2.14e-03168121.10.1070.11
DomainPI3Kc

ATR MTOR

2.14e-0316812SM00146
DomainIG

UNC5A HMCN2 NTRK3 NCAN ROR2 OBSCN CDON

2.33e-03421817SM00409
DomainIg_sub

UNC5A HMCN2 NTRK3 NCAN ROR2 OBSCN CDON

2.33e-03421817IPR003599
Domain-

PLPP3 PLPPR3

2.72e-03188121.20.144.10
DomainPI3/4_kinase_cat_dom

ATR MTOR

2.72e-0318812IPR000403
DomainPI3_PI4_kinase

ATR MTOR

2.72e-0318812PF00454
DomainPI3_4_KINASE_3

ATR MTOR

2.72e-0318812PS50290
DomainPI3_4_KINASE_1

ATR MTOR

2.72e-0318812PS00915
DomainPI3_4_KINASE_2

ATR MTOR

2.72e-0318812PS00916
DomainacidPPc

PLPP3 PLPPR3

2.72e-0318812SM00014
DomainP_Acid_Pase_2/haloperoxidase

PLPP3 PLPPR3

3.36e-0320812IPR000326
DomainPAP2

PLPP3 PLPPR3

3.36e-0320812PF01569
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NCOR1 FAM193B FAT1 HIVEP2 MTOR BCAS3 UBE3B OBSCN RAPGEF1 PCNX1 IRS1 KDM6B RIC1 RYR1 BAHCC1

4.21e-081105821535748872
Pubmed

UBE3B promotes breast cancer progression by antagonizing HIF-2α degradation.

UBE3B EPAS1

5.49e-06282237783786
Pubmed

mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK.

MTOR IRS1

5.49e-06282223607966
Pubmed

PI3K-mTORC2 but not PI3K-mTORC1 regulates transcription of HIF2A/EPAS1 and vascularization in neuroblastoma.

MTOR EPAS1

5.49e-06282226432405
Pubmed

Insulin signaling in type 2 diabetes: experimental and modeling analyses reveal mechanisms of insulin resistance in human adipocytes.

MTOR IRS1

5.49e-06282223400783
Pubmed

Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling.

PLK2 MTOR

5.49e-06282229448085
Pubmed

Regulation of histone demethylase KDM6B by hypoxia-inducible factor-2α.

KDM6B EPAS1

5.49e-06282225520177
Pubmed

Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.

MTOR IRS1

5.49e-06282215604215
Pubmed

Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2).

MTOR IRS1

5.49e-06282223863152
Pubmed

Lethal multiple pterygium syndrome, large cystic hygroma, and cleft palate: Rare and severe fetal presentations of RYR1- and NEB-related congenital myopathies.

NEB RYR1

5.49e-06282238520674
Pubmed

Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.

PPP2R2B ATR MTOR UBE3B

1.11e-055882431067491
Pubmed

Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.

MTOR EPAS1

1.64e-05382218945681
Pubmed

Overexpression of Akt1 upregulates glycogen synthase activity and phosphorylation of mTOR in IRS-1 knockdown HepG2 cells.

MTOR IRS1

1.64e-05382217721885
Pubmed

A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.

NTRK3 IRS1

1.64e-05382214668342
Pubmed

A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.

MTOR IRS1

1.64e-05382211287630
Pubmed

Roles of mTOR and JNK in serine phosphorylation, translocation, and degradation of IRS-1.

MTOR IRS1

1.64e-05382216099428
Pubmed

Hepatitis C virus activates the mTOR/S6K1 signaling pathway in inhibiting IRS-1 function for insulin resistance.

MTOR IRS1

1.64e-05382222457523
Pubmed

IRS1Ser³⁰⁷ phosphorylation does not mediate mTORC1-induced insulin resistance.

MTOR IRS1

1.64e-05382224333417
Pubmed

Reelin signaling pathway genotypes and Alzheimer disease in a Spanish population.

PLK2 RELN

1.64e-05382224384746
Pubmed

Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.

MTOR IRS1

1.64e-05382215001544
Pubmed

Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.

PPP2R2B PPP2R2C

1.64e-0538229514514
Pubmed

Hypoxia-inducible factor-1α protein negatively regulates load-induced bone formation.

MTOR EPAS1

1.64e-05382222081627
Pubmed

Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response.

ATR MTOR

3.28e-05482219955088
Pubmed

Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.

MTOR IRS1

3.28e-05482220203102
Pubmed

A tripartite complex composed of ETV6-NTRK3, IRS1 and IGF1R is required for ETV6-NTRK3-mediated membrane localization and transformation.

NTRK3 IRS1

3.28e-05482221804605
Pubmed

Over-expression of DNA-PKcs in renal cell carcinoma regulates mTORC2 activation, HIF-2α expression and cell proliferation.

MTOR EPAS1

3.28e-05482227412013
Pubmed

Autophagy plays beneficial effect on diabetic encephalopathy in type 2 diabetes: studies in vivo and in vitro.

MTOR IRS1

3.28e-05482228456145
Pubmed

MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632.

MTOR IRS1

3.28e-05482214579029
Pubmed

Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice.

RELN NCAN

3.28e-05482216324103
Pubmed

Docking motif-guided mapping of the interactome of protein phosphatase-1.

DDX31 WDR81 DNAI7 SPOCD1

3.96e-058082419389623
Pubmed

WFS1 Spectrum Disorder

PPP1R3A ABCC8 IRS1

3.97e-052882320301750
Pubmed

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.

GSE1 ROR2 PCNX1

5.41e-053182327321927
Pubmed

Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis.

MTOR IRS1

5.47e-05582216914728
Pubmed

Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain.

RELN NCAN

5.47e-0558229716537
Pubmed

Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro.

PPP2R2B PPP2R2C

5.47e-05582215578586
Pubmed

Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR.

MTOR IRS1

5.47e-05582219561084
Pubmed

Gene expression profiling of preplate neurons destined for the subplate: genes involved in transcription, axon extension, neurotransmitter regulation, steroid hormone signaling, and neuronal survival.

RELN RYR1

5.47e-05582219398467
Pubmed

C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment.

RELN RAPGEF1

5.47e-05582218506028
Pubmed

Migration of sympathetic preganglionic neurons in the spinal cord of a C3G-deficient mouse suggests that C3G acts in the reelin signaling pathway.

RELN RAPGEF1

8.19e-05682222351125
Pubmed

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene.

PCNX1 CDON

8.19e-05682222881374
Pubmed

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation.

MTOR IRS1

8.19e-05682216354680
Pubmed

mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells.

PPP2R2B MTOR

8.19e-05682216109716
Pubmed

Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth.

RELN MTOR

1.14e-04782217698586
Pubmed

HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.

PPP2R2B PPP2R2C

1.14e-04782225816751
Pubmed

Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A.

PPP2R2B MTOR

1.14e-04782222337773
Pubmed

HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.

MTOR EPAS1

1.14e-04782223103253
Pubmed

Reelin regulates the migration of late-born hippocampal CA1 neurons via cofilin phosphorylation.

RELN RAPGEF1

1.14e-04782236435394
Pubmed

Receptor-like protein tyrosine phosphatase zeta/RPTP beta is expressed on tangentially aligned neurons in early mouse neocortex.

RELN NCAN

1.14e-04782214757526
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

GSE1 ATR DROSHA UBE3B TONSL DLG1 CLSTN1 RIC1

1.51e-0465082838777146
Pubmed

The role of Vpr in HIV-1 pathogenesis.

PPP2R2B PPP2R2C

1.52e-04882215638722
Pubmed

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.

PPP2R2C IRS1

1.52e-04882219734900
Pubmed

Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A.

PPP2R2B PPP2R2C

1.52e-04882212912990
Pubmed

Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt.

MTOR IRS1

1.52e-04882225273559
Pubmed

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

ATR MTOR

1.52e-04882220810650
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

BCAS3 CD109 OBSCN NEB RYR1

1.56e-0421482522199357
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PLK2 HIVEP2 CARMIL2 MTOR BCAS3 NTRK3 ROR2 IRS1 CAMSAP2

1.95e-0486182936931259
Pubmed

Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy.

FAT1 RYR1

1.96e-04982223785297
Pubmed

Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.

PPP2R2B PPP2R2C

1.96e-04982219762425
Pubmed

Spatial and temporal regulation of GLUT4 translocation by flotillin-1 and caveolin-3 in skeletal muscle cells.

RAPGEF1 IRS1

2.44e-041082216455755
Pubmed

ACKR3 Regulation of Neuronal Migration Requires ACKR3 Phosphorylation, but Not β-Arrestin.

RELN GRK2

2.44e-041082230726732
Pubmed

Tel2 regulates the stability of PI3K-related protein kinases.

ATR MTOR

2.44e-041082218160036
Pubmed

Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons.

RELN RAPGEF1

2.44e-041082215062102
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

ATR MTOR

2.98e-041182220427287
Pubmed

Dlec1 is required for spermatogenesis and male fertility in mice.

BBS2 DLEC1

2.98e-041182233144677
Pubmed

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

NCOR1 MBTPS2 MTOR RAPGEF1 IRS1

3.21e-0425082518660489
Pubmed

Rheb binds and regulates the mTOR kinase.

ATR MTOR

3.57e-041282215854902
Pubmed

Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.

OR52B4 GTF2A1L

3.57e-041282223227193
Pubmed

Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.

PPP2R2B PPP2R2C

4.21e-041382218971272
Pubmed

Analysis of BCL6-interacting proteins by tandem mass spectrometry.

NCOR1 PLPP3 DROSHA

4.32e-046282316147992
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOR1 PLPP3 MTOR NCAN WDR81 DLG1 DIXDC1 CAMSAP2 UNC13A

4.43e-0496382928671696
Pubmed

A Method to Identify p62's UBA Domain Interacting Proteins.

NCOR1 RELN

4.91e-041482214702098
Pubmed

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling.

PLPP3 PLPPR3

4.91e-041482227641493
Pubmed

Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.

PPP2R2B PPP2R2C

4.91e-04148229400615
Pubmed

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.

PPP2R2B PPP2R2C

4.91e-041482216048649
Pubmed

Dorsally derived netrin 1 provides an inhibitory cue and elaborates the 'waiting period' for primary sensory axons in the developing spinal cord.

UNC5A NTRK3

4.91e-041482216510500
Pubmed

Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.

PPP2R2B PPP2R2C

4.91e-04148229013886
Pubmed

Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice.

RELN MTOR

5.65e-041582234639052
Pubmed

CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability.

ATR MTOR

5.65e-041582220864032
Pubmed

GABRA1 and STXBP1: novel genetic causes of Dravet syndrome.

NOL11 CLSTN1

5.65e-041582224623842
Pubmed

ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.

NCAN ADAMTS14

5.65e-041582238871984
Pubmed

Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.

PPP2R2B PPP2R2C

5.65e-041582216041367
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

FAM193B FAT1 NCAN PKD1L1 TONSL OBSCN RAPGEF1 MAP3K15 MSS51 ADAMTS14

5.71e-041215821015146197
Pubmed

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.

HIVEP2 KDM6B CAMSAP2

5.92e-046982332238831
Pubmed

Regulation of HIV-1 transcription by protein phosphatase 1.

PPP2R2B PPP2R2C

7.30e-041782217266553
Pubmed

[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].

PPP2R2B PPP2R2C

7.30e-041782221351466
Pubmed

Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.

GSE1 NTRK3 KDM6B

8.15e-047782329445148
Pubmed

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway.

GRK2 RAPGEF1

8.20e-041882214712229
Pubmed

A genome-wide association study of sleep habits and insomnia.

ADAMTS14 NAALADL2

8.20e-041882223728906
Pubmed

Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFβ-TRCP E3 Ubiquitin Ligase.

MTOR IRS1

8.20e-041882230240640
Pubmed

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.

CD109 WDR81

8.20e-041882224068962
Pubmed

Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.

PPP2R2B PPP2R2C

8.20e-041882223287597
Pubmed

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development.

PPP2R2B PPP2R2C

9.15e-041982232582689
Pubmed

Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia.

RELN NTRK3

9.15e-041982233723434
Pubmed

Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins.

OBSCN NEB

9.15e-041982227171814
Pubmed

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.

ATR MTOR

9.15e-041982220801936
Pubmed

Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.

NCOR1 KDM6B

1.12e-032182230254164
Pubmed

Novel interaction partners of Bardet-Biedl syndrome proteins.

BBS2 EPAS1

1.12e-032182218000879
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

NCOR1 GSE1 DROSHA OBSCN NEB RYR1

1.16e-0349782623414517
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NCOR1 TTLL5 MTUS2

1.16e-038782312465718
Pubmed

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

UNC5A RELN

1.23e-032282222726835
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R3A NCOR1 DDX31 WDR81 DNAI7 SPOCD1 RYR1

4.02e-07181477694
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

UNC5A HMCN2 NTRK3 ROR2 OBSCN CDON

3.61e-06161476593
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2B PPP2R2C

6.80e-0415472696
GeneFamilyCadherin related

FAT1 CLSTN1

8.77e-041747224
GeneFamilyWD repeat domain containing

PPP2R2B PPP2R2C BCAS3 WDR81

4.71e-03262474362
GeneFamilyReceptor Tyrosine Kinases|CD molecules

NTRK3 ROR2

4.84e-0340472321
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|COVID-19_Mild / Disease condition and Cell class

CERKL GRK2 HLA-G PCNX1 RIC1

1.36e-05165825ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|Classical_Monocyte / Disease condition and Cell class

CERKL GRK2 HLA-G PCNX1 RIC1

1.48e-05168825d50078614f7af74dc2aa4081c1708a5156ac51cf
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBLAC2 OBSCN MAP3K15 DNAI7 MTUS2

1.57e-05170825d99f61aa85ea3f775165cb433421e6f1cda4f96b
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBLAC2 OBSCN MAP3K15 DNAI7 MTUS2

1.57e-05170825615cf9639c66b3fbd984ebe3f345280005d3c38a
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP2R2B RELN NEB UNC13A RYR1

1.61e-05171825b2e753e811a7639956994609f73efcdb62d04f82
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN NEB MTUS2

1.66e-05172825ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN NEB MTUS2

1.66e-05172825bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R3A UNC5A ABCC8 MAP3K15 VWA5B1

1.80e-051758258362a46f5804333baa84cd56d450bc147f372a7e
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R3A UNC5A ABCC8 MAP3K15 VWA5B1

1.80e-051758258b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5A HMCN2 PLPP3 CD109 EPAS1

1.85e-0517682564e426f5e84884ce2c29acf6f4b958962a63927f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GMNC RELN FAT1 OBSCN NEB

2.29e-051848252cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GMNC RELN FAT1 OBSCN NEB

2.29e-05184825ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GMNC RELN FAT1 OBSCN NEB

2.29e-051848252b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GMNC PPP2R2B PLPP3 ABCC8 DIXDC1

2.54e-05188825a6cbe58c5029acefbfbb64c3bff570de4e5e2449
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

FAT1 HIVEP2 PLPP3 NABP1 KDM6B

2.60e-0518982546e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

FAT1 HIVEP2 PLPP3 NABP1 KDM6B

2.60e-05189825b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

FAT1 ABCC8 CD109 RAPGEF1 EPAS1

2.67e-051908257f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT1 NTRK3 ROR2 IRS1 ADAMTS14

2.88e-051938255de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT1 NTRK3 OBSCN IRS1 ADAMTS14

2.95e-051948252d66091097e106c7bee22e5281f50724700bdf8d
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMCN2 ABCC8 FLG2 NAALADL2 CDON

3.02e-05195825d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMCN2 ABCC8 FLG2 NAALADL2 CDON

3.02e-0519582519853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPP2R2C HIVEP2 DLG1 MTUS2 UNC13A

3.02e-051958252e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

PLPP3 MTOR HLA-G WDR81 FLG2

3.33e-05199825fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Aldh1a1_(SNc/VTA)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GMNC GTF2A1L SPOCD1

1.51e-0456823fedec1be5368a82a75f640e84809e4270dd57c85
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Aldh1a1_(SNc/VTA)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GMNC GTF2A1L SPOCD1

1.51e-04568231c101711d20817f65314fcf45a4f99d0934206a8
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERKL IRS1 ADAMTS14 UNC13A

2.33e-041638241eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX31 DROSHA ZNF280C VWA5B1

2.33e-04163824953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 HMCN2 ROR2

2.33e-04163824551b3788bcf494c6121e64ce5af72266de12a06b
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROR2 HSPBP1 HAL MTUS2

2.56e-04167824f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLK2 CD109 DNAI7 EPAS1

2.61e-0416882455c9de7b3a1d6cf7b02b020ff92ab4ede8d195cc
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PPP2R2B PPP2R2C ABCC8 UNC13A

2.67e-0416982496a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLG2 CLSTN1 EPAS1 RYR1

2.74e-041708240cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM193B CARMIL2 TONSL NEB

2.74e-041708242b5b1f8d13b9806b76b44a53f47a23dd9ff09808
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM193B CARMIL2 TONSL NEB

2.74e-0417082443c48267d8291c88263148a36fbb63c27f0e4f1c
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLG2 CLSTN1 EPAS1 RYR1

2.74e-041708242d880223d01bde4bf777bd6f50b7d2768489075f
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLK2 PLPP3 OBSCN PCNX1

2.74e-04170824af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

GMNC CD109 DLEC1 DNAI7

2.80e-0417182474be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R3A HMCN2 ROR2 CDON

2.80e-0417182482de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CERKL GRK2 CARMIL2 PCNX1

2.80e-04171824d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R3A HMCN2 ROR2 CDON

2.80e-0417182409e653973962fb884878089d281f0947f7a285f6
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CERKL ABCC8 NEB UNC13A

2.80e-04171824fa5cc720bd0045d0307439be547b41d56def5b43
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

CD109 PLPPR3 TDRD6 BAHCC1

2.86e-04172824a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MBLAC2 MCM9 ADAMTS14 RYR1

2.92e-04173824b6bb2a136a40f0946bbcde8d5972d3f059d080c7
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|Classical_Monocyte / Disease condition and Cell class

CERKL GRK2 HLA-G PCNX1

3.05e-0417582435ea2ed93538e6bf803029fcf7d9243f93e7733d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GSE1 PLPP3 CD109 EPAS1

3.12e-04176824dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

3.19e-04177824692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

3.19e-04177824c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCell390C-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HIVEP2 CARMIL2 DROSHA TONSL

3.33e-041798243edcd1356e49b1f5514c585861999e079ca5e579
ToppCell390C-Lymphocytic-ILC-ILC-1|390C / Donor, Lineage, Cell class and subclass (all cells)

HIVEP2 CARMIL2 DROSHA TONSL

3.33e-04179824e7045e27f0eb88f552b31c04b56d78e5ccd7a36c
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5A PLK2 PLPP3 EPAS1

3.33e-04179824ba38177ffcf3a20f02afeeaaa91bc8eab8d1ac05
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC5A PLK2 PLPP3 EPAS1

3.33e-04179824d121351b4c3b91108e6c5753d18a44d676f38d4c
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HMCN2 PLPP3 NAALADL2 CDON

3.40e-041808249adebde5f4ca6dcb90e9113622862e14298465ac
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC8 OBSCN DNAI7 MTUS2

3.47e-0418182409a574a3257e25c8b05a2ab20623a6b07331411a
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|COVID-19_Severe / Disease condition and Cell class

CERKL GRK2 HLA-G PCNX1

3.47e-041818240d07a67e8ee3bca687b378afbc4044434e63556d
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC8 OBSCN DNAI7 MTUS2

3.47e-04181824ac4142aa93706b7067f63d2d38e2456859e60768
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERKL UNC5A ABCC8 UNC13A

3.54e-04182824398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

HIVEP2 GRK2 CARMIL2 PCNX1

3.54e-04182824877b6e611626628e709568747512f2827ebb2795
ToppCell(00)_Basal-(0)_uninjured|(00)_Basal / shred by cell type and Timepoint

PPP2R2B FAT1 PLPP3 EPAS1

3.54e-04182824c02c9cab4389d80f318f4bb8d703c1e719672624
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

CERKL GRK2 HLA-G PCNX1

3.62e-0418382422bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

GRK2 GSE1 RAPGEF1 PCNX1

3.69e-04184824791f1bcb954aadc63d4117c400537d036f68734d
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 NTRK3 DIXDC1 IRS1

3.77e-04185824e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell18-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

PPP2R2B RELN PPP2R2C UNC13A

3.77e-04185824d2a266724f3f70f746a78034f308d98f8b7a66e3
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CERKL PLPPR3 DLEC1 DNAI7

3.77e-041858243e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NTRK3 ROR2 DIXDC1 IRS1

3.85e-041868246add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellsaliva-Severe-critical_progression_d28-40|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIVEP2 DLG1 NABP1 KDM6B

3.85e-041868240095560ca776b01aa473ad4d6015ed78fc93ff51
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 RAPGEF1 KDM6B EPAS1

3.85e-04186824f8ed078684ce6d914fd9cb1f0ef4aba36db39b3f
ToppCellfacs-Heart-LA-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 RAPGEF1 KDM6B EPAS1

3.85e-041868241d08e60d239153c9e5ea42135d702d494d8b42b1
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PPP2R2B RELN PPP2R2C CDON

3.85e-041868248915436d09775f2828a7678af203b1082b36e21c
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-osteoclast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ROR2 CD109 DIXDC1 ADAMTS14

3.85e-04186824c9dfcf7bba7e5ef97ad5d9b7084fba932c91ab68
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

FAT1 ABCC8 CD109 EPAS1

3.92e-04187824f3548817f2fded5978137bb252cb628ac199e4f6
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CERKL PLPPR3 DLEC1 DNAI7

3.92e-041878249e10ed56090d82589bc457788282f664b70ace4b
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CERKL PPP2R2B ABCC8 UNC13A

3.92e-0418782498477ba04a42a8da80a72f41a182429f46283595
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLK2 PLPP3 NTRK3 ADAMTS14

3.92e-0418782439756ab418267151d86f9c2553db859f71900bb1
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GMNC PPP2R2B PLPP3 ABCC8

4.00e-04188824176a207dde6dd122a11e6c67c6299bc5179ff049
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.00e-0418882490dc0e15798d0b984518ad58c7e416e30aff687a
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A FAT1 NTRK3 CD109

4.00e-0418882461f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCelldroplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A FAT1 NTRK3 CD109

4.00e-041888247553ef7de3575af4cf34704b405b551c1af8eb83
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ROR2 CD109 DIXDC1 ADAMTS14

4.00e-04188824762b52f21d2bc5409f86746a904c4358490be9c0
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.00e-04188824f63dfd076ced81013918363282ae25cbbd8948ae
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GMNC PPP2R2B PLPP3 ABCC8

4.00e-041888246fb37e3b139955e6ee6be26ab6cd3ce85d765ca6
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.00e-041888240554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCellfacs-Heart-LA/RA-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.09e-04189824a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 PPP2R2C HIVEP2 KDM6B

4.09e-041898241cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCellfacs-Heart-LA/RA|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.09e-04189824efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 ROR2 OBSCN

4.17e-041908243b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CERKL PPP2R2B ABCC8 UNC13A

4.17e-041908242375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 NTRK3 ROR2 CDON

4.17e-04190824efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellControl-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

GSE1 PLPP3 ABCC8 EPAS1

4.17e-041908244e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 ROR2 OBSCN

4.17e-04190824be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FAT1 ROR2 OBSCN

4.17e-04190824dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CERKL PPP2R2B ABCC8 UNC13A

4.17e-04190824b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.25e-04191824c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RELN NTRK3 PLPPR3 CDON

4.25e-04191824156b467187331ac6ca390d6ca861d9670bb7b956
ToppCelldroplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.25e-0419182497fb4232417a39801e87725755fd16a57c250209
ToppCelldroplet-Heart-nan-3m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.25e-0419182464070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.25e-04191824715f5b449b8e075959c05a5b38389df319663164
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLPP3 CD109 RAPGEF1 EPAS1

4.34e-0419282427ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT1 ROR2 IRS1 ADAMTS14

4.34e-0419282467e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R3A ABCC8 OBSCN MTUS2

4.34e-041928240bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PLK2 RELN PLPPR3 CDON

4.34e-04192824d88753b200d9c8da6716222d697ddf0a1548d6c8
Diseasebody weight

PPP1R3A NCOR1 RELN HIVEP2 GTF2A1L GSE1 MTOR ABCC8 ROR2 ZNF280C BBS2 IRS1 ADAMTS14 EPAS1

5.83e-0612617914EFO_0004338
Diseasereticulocyte count

PLK2 FAT1 CCM2 ATR PLPP3 BCAS3 ZNF280C HLA-G PLPPR3 IRS1 NABP1 SPOCD1

2.10e-0510457912EFO_0007986
Diseasemuscle measurement

PLK2 NEB

4.23e-054792EFO_0004515
DiseaseTYPE 2 DIABETES MELLITUS

PPP1R3A ABCC8 IRS1

5.77e-0528793125853
DiseaseType 2 diabetes mellitus

PPP1R3A ABCC8 IRS1

5.77e-0528793cv:C0011860
Diseaseadenoid cystic carcinoma (is_implicated_in)

ATR NTRK3

7.04e-055792DOID:0080202 (is_implicated_in)
DiseaseLarge cell carcinoma of lung

ATR MTOR NTRK3

8.66e-0532793C0345958
DiseaseMULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE

NEB RYR1

1.05e-046792C1854678
Diseaselower face morphology measurement

BCAS3 ROR2 CD109 EPAS1

2.14e-04109794EFO_0010948
Diseaseasparaginase-induced acute pancreatitis

ZNF701 NEB

2.52e-049792EFO_1001507
Diseaseresponse to corticosteroid, age at assessment

PLK2 HIVEP2

3.14e-0410792EFO_0008007, GO_0031960
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2B PPP2R2C

4.59e-0412792DOID:1441 (implicated_via_orthology)
DiseaseCongenital myopathy (disorder)

NEB RYR1

4.59e-0412792C0270960
Diseaseeosinophil count

PPP1R3A CCM2 HIVEP2 CARMIL2 GSE1 ATR HLA-G PLPPR3 PCNX1 KDM6B CLSTN1 BAHCC1

5.77e-0414887912EFO_0004842
Diseaseschizophrenia (implicated_via_orthology)

RELN HIVEP2 MTOR

8.17e-0468793DOID:5419 (implicated_via_orthology)
DiseaseManic Disorder

RELN NCAN DIXDC1

9.26e-0471793C0024713
Diseasekidney volume

BCAS3 RAPGEF1

1.05e-0318792EFO_0600044
Diseaseintellectual disability (implicated_via_orthology)

HIVEP2 ZNF280D IRS1

1.09e-0375793DOID:1059 (implicated_via_orthology)
Diseasetype 2 diabetes mellitus (is_implicated_in)

PPP1R3A MTOR ABCC8 IRS1

1.17e-03171794DOID:9352 (is_implicated_in)
Diseasepolycystic kidney disease (biomarker_via_orthology)

MTOR EPAS1

1.18e-0319792DOID:0080322 (biomarker_via_orthology)
DiseaseManic

RELN NCAN DIXDC1

1.22e-0378793C0338831
DiseaseDepression, Bipolar

RELN NCAN DIXDC1

1.26e-0379793C0005587
DiseaseGlioblastoma

NCOR1 FAT1 MTOR

1.26e-0379793C0017636
Diseaseend stage renal disease (implicated_via_orthology)

MTOR IRS1

1.30e-0320792DOID:783 (implicated_via_orthology)
DiseaseGiant Cell Glioblastoma

NCOR1 FAT1 MTOR

1.51e-0384793C0334588
Diseasewaist-hip ratio

PPP1R3A CCM2 GSE1 ZNF280D ABCC8 DLG1 PCNX1 DIXDC1 DLEC1 CDON

1.58e-0312267910EFO_0004343
Diseasephosphatidylcholine 34:3 measurement

PPP2R2C NABP1

1.58e-0322792EFO_0010377
Diseasereticulocyte measurement

FAT1 CCM2 ATR PLPP3 PLPPR3 IRS1 NABP1 KDM6B SPOCD1

1.99e-031053799EFO_0010700
DiseasePR interval

FAT1 UBE3B OBSCN DLG1 DLEC1 EPAS1

2.14e-03495796EFO_0004462
Diseasepsychosis predisposition measurement

CERKL VWA5B1

2.21e-0326792EFO_0008337
DiseaseAdenocarcinoma of large intestine

GRK2 ROR2 MAP3K15

2.21e-0396793C1319315
Diseaseoptic disc size measurement

BCAS3 RAPGEF1 DLEC1 ADAMTS14

2.26e-03205794EFO_0004832
DiseaseAdenocarcinoma of lung (disorder)

PLK2 ATR NTRK3 MAP3K15

2.30e-03206794C0152013
Diseasecorpus callosum mid-anterior volume measurement

GMNC CCM2

2.38e-0327792EFO_0010297
Diseaseblood strontium measurement

PLK2 PPP2R2C

2.38e-0327792EFO_0021531
Diseaseacute kidney failure (implicated_via_orthology)

MTOR EPAS1

2.38e-0327792DOID:3021 (implicated_via_orthology)
DiseaseHodgkins lymphoma, multiple myeloma, non-Hodgkins lymphoma

ZNF280D HLA-G

2.56e-0328792EFO_0000183, EFO_0001378, EFO_0005952
Diseaselung small cell carcinoma (is_implicated_in)

FAT1 MTOR

2.56e-0328792DOID:5409 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
SVHVELFTHPGTGEH

UNC13A

1531

Q9UPW8
HIESTHTPHEFSTIC

ZNF280D

376

Q6N043
LTGHSIFDFTHPCDH

EPAS1

126

Q99814
LTEVITAAEFHPHHC

PPP2R2B

221

Q00005
LTEVITASEFHPHHC

PPP2R2C

221

Q9Y2T4
ASTFLPVSHLDHHGN

BAHCC1

131

Q9P281
SHGLHLVPFIHSAAE

CARMIL2

951

Q6F5E8
SFSGHDPQHHTIDSL

DIXDC1

526

Q155Q3
ENVHGFVSHSHISPI

DLG1

146

Q12959
ESHSLHSHPAAFEPS

GSE1

601

Q14687
SHVHLHVISQDFDSP

APTX

271

Q7Z2E3
GASTPTHHLSLHSDD

CCM2

236

Q9BSQ5
FVHPEHRSFVDLSGH

CLSTN1

831

O94985
HVSSDHLHFDQGPLV

CCDC87

501

Q9NVE4
TLGHDFHVFQILTHP

BCAS3

371

Q9H6U6
DPSHAEHHDHVVFLT

ADAMTS14

346

Q8WXS8
SHPFSKSATEHVQGH

GRK2

121

P25098
SEHTSHSAHPEPALN

MTUS2

271

Q5JR59
NIGPTHHEIDTASSH

RIC1

1176

Q4ADV7
KHSQDPGTHVVSHFV

NOL11

346

Q9H8H0
THVTHHPVFDYEATL

HLA-G

211

P17693
EARISEHAPHGHFVT

FAT1

2396

Q14517
HPEFSTFNPESVHGH

FAT1

4281

Q14517
TDSEVHSGVSHRPHS

FLG2

1351

Q5D862
HEEPEFTVHERHGTT

FLG2

1606

Q5D862
SEVHSEASPTHSGHT

FLG2

2186

Q5D862
DSASPLHHINHGITT

NTRK3

476

Q16288
LHHINHGITTPSSLD

NTRK3

481

Q16288
ETGQTHHPDLVAAFH

MSS51

341

Q4VC12
GTTLHIDHVELDHSG

HMCN2

1771

Q8NDA2
EVSHHGRLGPSAHSS

KDM6B

431

O15054
SEHTHKAHLVPEGTS

PCNX1

656

Q96RV3
HSGTSHTVFHLLGIP

OR52B4

6

Q8NGK2
VFTSAAFHELGLHPH

DDX31

226

Q9H8H2
GGHHRPDSSTLHTDD

IRS1

596

P35568
PESHSLHRSSVSLDH

MEIOSIN

426

C9JSJ3
VTVHPHLAEIHSDSI

RELN

186

P78509
LTPEHHHLTSEGSAL

PPP1R3A

596

Q16821
ASGTHLAPGHSHSLE

OBSCN

6951

Q5VST9
SSLTEPFSEHGHVDL

ATR

726

Q13535
HIVDIHDFSLGSSPH

CD109

671

Q6YHK3
LLDSDHHPSEIAESH

HAL

371

P42357
GIFTGESHVVHPSIH

BBS2

421

Q9BXC9
EAFPVSEHHQHSDLT

FAM193B

231

Q96PV7
SLTRTHVDFEHPHHL

CDON

1076

Q4KMG0
HYDHVSALHPVSTPS

DNAI7

256

Q6TDU7
AHSLHGVPHVITATL

CERKL

306

Q49MI3
PLLAVATHVHFDHSG

MBLAC2

76

Q68D91
VGHPLHLHYTVSITS

MBTPS2

411

O43462
LPAESDAVTVHSTHG

CRIPAK

411

Q8N1N5
HTDHEFILSFSPHEL

DLEC1

691

Q9Y238
TTPHGFETHTLEEHN

RYR1

4971

P21817
QPHHGLEAHTVFSVF

PKD1L1

1201

Q8TDX9
SGEGATFTQSHHHLP

CAMSAP2

381

Q08AD1
ALSSAPTHIIGHVFH

OR11H7

186

Q8NGC8
PTHIIGHVFHSVSSL

OR11H7

191

Q8NGC8
TPSIHLISGHAHVVS

MTOR

631

P42345
HHLGHLLSVPDESSA

MAP3K15

971

Q6ZN16
LIHSFEDHSHVSPGA

MCM9

931

Q9NXL9
VRTEHSPFHEHVLGA

HSPBP1

281

Q9NZL4
FPDHHEGHLTLLRSS

DROSHA

1166

Q9NRR4
GVHTGPESREHQFSH

NABP1

151

Q96AH0
AHSPGHVSNHFTTES

TDRD6

681

O60522
TPLHSTATHGEDFHI

GMNC

251

A6NCL1
VSDHKHHPSDVLAGF

PLPP3

246

O14495
VVSHSPFDPHHRGST

NCOR1

1541

O75376
FRAHHPTSQHGDLET

NCAN

356

O14594
GHLTSVHSPEEHSFI

NCAN

1121

O14594
VHSPEEHSFINSFGH

NCAN

1126

O14594
HSHHLSSTDFPELGG

ROR2

346

Q01974
EGILSDGVTESHHLH

ABCC8

91

Q09428
QLGSSFHSHLPELHI

ZNF321P

86

Q8N8H1
ARPGTLHDFHSHEIA

RAPGEF1

831

Q13905
DSASIVTIDAHAPHH

PLPPR3

576

Q6T4P5
DESLSTSPHGALHQH

GTF2A1L

276

Q9UNN4
DHLFLIPVPHSSDTH

TONSL

941

Q96HA7
PIASEDTTGQHDHHF

SPOCD1

771

Q6ZMY3
GRHTLHHSSPTSEAE

UNC5A

406

Q6ZN44
GHHHSVFYSSVDELP

UBE3B

806

Q7Z3V4
HEDLPTLSHHPSFTL

ZNF566

146

Q969W8
HASPSVNRHHSAGEI

ZBTB49

176

Q6ZSB9
HIESTHTPHEFSTIC

ZNF280C

371

Q8ND82
HHSHSGPEISRIIVD

PLK2

61

Q9NYY3
LGSSFHSHLPEVHIF

ZNF701

206

Q9NV72
IHSSYPLEHVAEHTG

HIVEP2

1251

P31629
HVPHHISDVLSDITY

WDR81

436

Q562E7
LTAHGFHEVHPSSTD

TTLL5

81

Q6EMB2
LESGHFDASHVRSPT

VWA5B1

81

Q5TIE3
SPDRYIIVGSHHHTA

NAALADL2

441

Q58DX5
EKSEHSEAPDHHLST

NEB

6551

P20929