Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

EGFR ROS1 FGFR2 EPHA4 EPHB1

8.68e-05651385GO:0004714
DomainPROTEIN_KINASE_TYR

LMTK2 EGFR ROS1 FGFR2 EPHA4 EPHB1

8.31e-05971386PS00109
DomainTyr_kinase_AS

LMTK2 EGFR ROS1 FGFR2 EPHA4 EPHB1

8.31e-05971386IPR008266
DomainAT_hook

PRR12 BAZ2A KMT2A

2.06e-04161383PF02178
DomainAldolase_II

ADD1 ADD3

3.22e-0441382SM01007
DomainAldolase_II/adducin_N

ADD1 ADD3

3.22e-0441382IPR001303
DomainAldolase_II

ADD1 ADD3

3.22e-0441382PF00596
Domain-

ADD1 ADD3

3.22e-04413823.40.225.10
DomainPkinase_Tyr

LMTK2 EGFR ROS1 FGFR2 EPHA4 EPHB1

3.94e-041291386PF07714
DomainTyr_kinase_cat_dom

EGFR ROS1 FGFR2 EPHA4 EPHB1

4.91e-04881385IPR020635
DomainTyrKc

EGFR ROS1 FGFR2 EPHA4 EPHB1

4.91e-04881385SM00219
PathwayWP_ENDOMETRIAL_CANCER

FOS CASP9 EGFR FGFR2 POLK SOS2

2.38e-0663876M39623
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ARHGAP32 DNAJC13 IRS4 SIPA1L3 ZNF280C ZDHHC5 LMTK2 TRIOBP KIAA1549 RNF213 AP3B1 CEP350 TTC7B NUP155 SMG7 EGFR FMN2 MPHOSPH9 HADHB HERC1 NEURL4 PRRC2B ILKAP

3.87e-1110491402327880917
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SH3TC2 ARHGAP32 ARHGEF28 SIPA1L3 ZDHHC5 RNF213 ZNF407 ATP10A CEP350 PRR12 VPS13D TNRC18 NEURL4 TRAPPC9

1.41e-084931401415368895
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SAMD9 ARHGEF28 AP3B1 MAST2 ANKZF1 SBNO2 PRR12 EIF2D MAP7D1 NUP155 GORASP1 KMT2A CMTR2 PLXNB1 PRRC2B

6.42e-086501401538777146
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SYNRG ARHGAP32 IRS4 ARHGEF28 SIPA1L3 AAK1 LMTK2 MAST2 CEP350 VPS13D MAP7D1 FMN2 KMT2A MPHOSPH9 TRAPPC9 BICC1

4.25e-078611401636931259
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SYNRG PCNX3 PPRC1 SIPA1L3 ZDHHC5 AKNA LMTK2 MAST2 SBNO2 PKMYT1 PRR12 TNRC18 ZNF592 KCNH2 FGFR2 HERC1 TRAPPC9 PRRC2B

5.25e-0711051401835748872
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

VPS37A NBEAL1 TUT1 MAST2 CEP350 RIOX2 TNRC18 SMG7 EGFR SKOR2 PDE4DIP HADHB TARBP2 PRRC2B

8.26e-076891401436543142
Pubmed

Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively.

FOS LAMA1 SOS2

2.21e-06714038276400
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KLF8 DNAJC13 VPS37A DYM SIPA1L3 TOM1L1 FRMPD1 AAK1 TRIOBP RNF213 ATP8B1 ATP10A SBNO2 TNRC18 SMG7 EGFR RERE POLK TRAPPC9 SOS2

2.32e-0614891402028611215
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

RBBP6 KIAA1549 RNF213 MAST2 SLC40A1 TTC7A ZNF469 MAP7D1 SMG7 ZNF592 BAZ2A FMN2 BICRAL RERE LONRF3 TARBP2 PRRC2B

2.75e-0611161401731753913
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ARHGAP32 DNAJC13 OXR1 SIPA1L3 AAK1 KIAA1549 AP3B1 JMY ADD1 ADD3 DZANK1 MAP7D1 TTC7B VCAN PDE4DIP KMT2A HADHB TRAPPC9 PRRC2B

5.03e-0614311401937142655
Pubmed

Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis.

FOS EGFR EPHA4

5.27e-069140332601248
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

DNAJC13 LMTK2 MUC16 AASDH MAST2 EGFR FGFR2 HERC1 EPHA4 ILKAP

8.43e-064201401028065597
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ARHGAP32 DNAJC13 SIPA1L3 TRPC4 AAK1 TRIOBP ADD1 DZANK1 MAP7D1 KCNJ10 PDE4DIP UNC79 NEURL4 PRRC2B EPHA4

8.48e-069631401528671696
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ARHGAP32 IRS4 ZDHHC5 TRIOBP ADD1 ADD3 TTC7B NUP155 EGFR EPHA4

8.61e-064211401036976175
Pubmed

Ephrin/ephrin receptor expression during early stages of mouse inner ear development.

NEUROG1 EPHA4 EPHB1

1.37e-0512140321465626
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TTF2 SYNRG IRS4 RBBP6 AP3B1 ADD1 ADD3 SMG7 BAZ2A KMT2A PRRC2B

1.49e-055491401138280479
Pubmed

Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4.

TRPC4 EGFR

1.61e-052140216144838
Pubmed

Identification of New Genetic Clusters in Glioblastoma Multiforme: EGFR Status and ADD3 Losses Influence Prognosis.

ADD3 EGFR

1.61e-052140233172155
Pubmed

Effects of genetic variation in adducin on left ventricular diastolic function as assessed by tissue Doppler imaging in a Flemish population.

ADD1 ADD3

1.61e-052140218475162
Pubmed

Regulation of anoikis resistance by NADPH oxidase 4 and epidermal growth factor receptor.

NOX4 EGFR

1.61e-052140228081539
Pubmed

Versican G3 domain regulates neurite growth and synaptic transmission of hippocampal neurons by activation of epidermal growth factor receptor.

EGFR VCAN

1.61e-052140216648628
Pubmed

Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling.

EGFR VCAN

1.61e-052140221079779
Pubmed

RME-8 regulates trafficking of the epidermal growth factor receptor.

DNAJC13 EGFR

1.61e-052140218307993
Pubmed

Promoter region of the murine fibroblast growth factor receptor 2 (bek/KGFR) gene.

EGFR FGFR2

1.61e-05214021408137
Pubmed

The Impact of Human Mammary Tumor Virus (HMTV) on the Expression of Epidermal Growth Factor Receptor (EGFR) and Death-Domain Associated Protein (DAXX) in Breast Carcinoma Tissues.

DAXX EGFR

1.61e-052140237396746
Pubmed

Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer.

EGFR ROS1

1.61e-052140224349229
Pubmed

Increased expression of phosphorylated adducin in tumor cells.

ADD1 ADD3

1.61e-052140232237935
Pubmed

Adducins regulate remodeling of apical junctions in human epithelial cells.

ADD1 ADD3

1.61e-052140220810786
Pubmed

Trans-activation response (TAR) RNA-binding protein 2 is a novel modulator of transient receptor potential canonical 4 (TRPC4) protein.

TRPC4 TARBP2

1.61e-052140224563462
Pubmed

Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.

EGFR FGFR2

1.61e-052140224550739
Pubmed

Decreased HCRP1 promotes breast cancer metastasis by enhancing EGFR phosphorylation.

VPS37A EGFR

1.61e-052140227311861
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

DNAJC13 RBBP6 SIPA1L3 ZDHHC5 MAST2 ATP10A MAP7D1 ZNF592 PRRC2B

1.68e-05361140926167880
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

EGFR FGFR2 EPHA4 EPHB1

2.05e-0540140430898150
Pubmed

The protein tyrosine kinase family of the human genome.

EGFR ROS1 FGFR2 EPHA4 EPHB1

2.22e-0583140511114734
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

SYNRG SIPA1L3 ZDBF2 ADD1 ADD3 CEP350 VPS13D

2.34e-05209140736779422
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

ZDHHC5 RBM28 AP3B1 CEP350 MAP7D1 GORASP1 PDE4DIP PRRC2B

2.97e-05298140832353859
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SYNRG DNAJC13 AAK1 TRIOBP DAXX AP3B1 ADD1 CEP350 RIOX2 MAP7D1 SMG7 PRRC2B

3.90e-057241401236232890
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TTF2 SYNRG ARHGAP32 SIPA1L3 AAK1 CASP9 MAST2 CEP350 EIF2D SMG7 MPHOSPH9 NEURL4 PRRC2B

4.36e-058531401328718761
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

AKNA SYBU ANKZF1 MAP7D1 TTC7B PDE4DIP NEURL4

4.67e-05233140737704626
Pubmed

Both EGFR kinase and Src-related tyrosine kinases regulate human ether-à-go-go-related gene potassium channels.

EGFR KCNH2

4.81e-053140218617000
Pubmed

Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer.

KLF8 EGFR

4.81e-053140226025929
Pubmed

Immunohistochemical studies on the expression and estrogen dependency of EGF and its receptor and C-fos proto-oncogene in the uterus and vagina of normal and neonatally estrogen-treated mice.

FOS EGFR

4.81e-05314028800404
Pubmed

Beyond EGFR, ALK and ROS1: Current evidence and future perspectives on newly targetable oncogenic drivers in lung adenocarcinoma.

EGFR ROS1

4.81e-053140233053439
Pubmed

A yeast three-hybrid method to clone ternary protein complex components.

EGFR SOS2

4.81e-05314028923966
Pubmed

Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination.

LIFR EGFR

4.81e-053140215385618
Pubmed

V3 versican isoform alters the behavior of human melanoma cells by interfering with CD44/ErbB-dependent signaling.

EGFR VCAN

4.81e-053140221078678
Pubmed

Differential expressions of the eph family of receptor tyrosine kinase genes (sek, elk, eck) in the developing nervous system of the mouse.

EPHA4 EPHB1

4.81e-05314027609620
Pubmed

Analysis of the status of EGFR, ROS1 and MET genes in non-small cell lung adenocarcinoma.

EGFR ROS1

4.81e-053140228952227
Pubmed

Comparable clinical outcomes in patients with HER2-mutant and EGFR-mutant lung adenocarcinomas.

EGFR ROS1

4.81e-053140228063177
Pubmed

Clinical characteristics of non-small cell lung cancer patients with EGFR mutations and ALK&ROS1 fusions.

EGFR ROS1

4.81e-053140235081265
Pubmed

PD-L1 expression in ROS1-rearranged non-small cell lung cancer: A study using simultaneous genotypic screening of EGFR, ALK, and ROS1.

EGFR ROS1

4.81e-053140230475455
Pubmed

Immunofluorescence localization of an adducin-like protein in the chromosomes of mouse oocytes.

ADD1 ADD3

4.81e-05314021864459
Pubmed

Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG proteins in the heart.

TRIOBP KCNH2

4.81e-053140229507111
Pubmed

Genome-wide association study of major recurrent depression in the U.K. population.

VCAN BICC1

4.81e-053140220516156
Pubmed

High prevalence of ROS1 gene rearrangement detected by FISH in EGFR and ALK negative lung adenocarcinoma.

EGFR ROS1

4.81e-053140232979347
Pubmed

Epistatic interaction between alpha- and gamma-adducin influences peripheral and central pulse pressures in white Europeans.

ADD1 ADD3

4.81e-053140215834281
Pubmed

Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy.

EGFR FGFR2

4.81e-053140221173787
Pubmed

Cost-effectiveness analysis comparing companion diagnostic tests for EGFR, ALK, and ROS1 versus next-generation sequencing (NGS) in advanced adenocarcinoma lung cancer patients.

EGFR ROS1

4.81e-053140232928143
Pubmed

Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice.

ADD1 ADD3

4.81e-053140210485892
Pubmed

Autosomal recessive polycystic kidney disease epithelial cell model reveals multiple basolateral epidermal growth factor receptor sorting pathways.

EGFR BICC1

4.81e-053140220519437
Pubmed

Role of the adducin family genes in human essential hypertension.

ADD1 ADD3

4.81e-053140215716695
Pubmed

EGFR mutations and ROS1 and ALK rearrangements in a large series of non-small cell lung cancer in South India.

EGFR ROS1

4.81e-053140232881404
Pubmed

Hepatoprotective effects of Methyl ferulic acid on alcohol-induced liver oxidative injury in mice by inhibiting the NOX4/ROS-MAPK pathway.

NOX4 ROS1

4.81e-053140228890346
Pubmed

[Clinicopathological significance in non-small cell lung cancer with mutations and co-mutations of EGFR, ALK and ROS1].

EGFR ROS1

4.81e-053140233677892
Pubmed

ALK and ROS1 testing on lung cancer cytologic samples: Perspectives.

EGFR ROS1

4.81e-053140228743163
Pubmed

EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling.

FOS EGFR

4.81e-053140230361264
Pubmed

EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer.

LIFR EGFR

4.81e-053140232963351
Pubmed

Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome.

ADD1 ADD3

4.81e-053140218667944
Pubmed

Functional coding/non-coding variants in EGFR, ROS1 and ALK genes and their role in liquid biopsy as a personalized therapy.

EGFR ROS1

4.81e-053140233038629
Pubmed

Detecting EGFR mutations and ALK/ROS1 rearrangements in non-small cell lung cancer using malignant pleural effusion samples.

EGFR ROS1

4.81e-053140230565433
Pubmed

It's not just baby's babble/Babel: recent progress in understanding the language of early mammalian development: a minireview.

EGFR FGFR2

4.81e-05314029890755
Pubmed

Arterial properties in relation to genetic variations in the adducin subunits in a white population.

ADD1 ADD3

4.81e-053140218787518
Pubmed

Epidermal Growth Factor Receptor (EGFR) Mutations and Anaplastic Lymphoma Kinase/Oncogene or C-Ros Oncogene 1 (ALK/ROS1) Fusions Inflict Non-Small Cell Lung Cancer (NSCLC) Female Patients Older Than 60 Years of Age.

EGFR ROS1

4.81e-053140230580372
Pubmed

The clinical value of the combined detection of sEGFR, CA125 and HE4 for epithelial ovarian cancer diagnosis.

MUC16 EGFR

4.81e-053140232016961
Pubmed

The oncogenic ADAMTS1-VCAN-EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma.

EGFR VCAN

4.81e-053140239333870
Pubmed

Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation.

FOS LIFR EGFR FGFR2

5.43e-0551140426764350
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF280C AAK1 AKNA LMTK2 TRIOBP KIAA1549 NUP155 SMG7 ZNF592 PLXNB1

5.98e-055291401014621295
Pubmed

Human transcription factor protein interaction networks.

ARHGAP32 KLF8 IRS4 RBBP6 FOS RBM28 ZFPM2 PRR12 MAP7D1 SMG7 ZNF592 KMT2A HADHB RERE HERC1 TRAPPC9 PRRC2B

6.50e-0514291401735140242
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ARHGAP32 IRS4 RBBP6 ZNF469 TNRC18 NUP155 NFE2L1 NEURL4 SOS2

6.53e-05430140935044719
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SYNRG DNAJC13 RBBP6 AAK1 DAXX ADD1 EIF2D EGFR ZNF592 BAZ2A KMT2A RERE

7.37e-057741401215302935
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

DNAJC13 ZDHHC5 MUC16 RNF213 AP3B1 ADD1 ADD3 CEP350 NUP155 EGFR MPHOSPH9 PRRC2B

7.64e-057771401235844135
Pubmed

Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

CEP350 VPS13D PDE4DIP RERE

7.85e-055614049455484
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TTF2 SYNRG VPS37A AAK1 DAXX AP3B1 ANKZF1 ADD1 ADD3 CEP350 SMG7 GORASP1 LSM11 MPHOSPH9

8.14e-0510381401426673895
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

ARHGAP32 ZDHHC5 ADD3 PRR12 NUP155 EGFR

9.35e-05180140635198878
Pubmed

Ten-m2 is required for the generation of binocular visual circuits.

FOS EPHB1

9.60e-054140223884953
Pubmed

Comparison of PD-L1, EGFR, ALK, and ROS1 Status Between Surgical Samples and Cytological Samples in Non-Small Cell Lung Carcinoma.

EGFR ROS1

9.60e-054140234558414
Pubmed

S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development.

UNCX NEUROG1

9.60e-054140224449764
Pubmed

Signaling by ephrinB1 and Eph kinases in platelets promotes Rap1 activation, platelet adhesion, and aggregation via effector pathways that do not require phosphorylation of ephrinB1.

EPHA4 EPHB1

9.60e-054140214576067
Pubmed

Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17.

FOS EGFR

9.60e-054140222772468
Pubmed

Nuclear FGFR2 Interacts with the MLL-AF4 Oncogenic Chimera and Positively Regulates HOXA9 Gene Expression in t(4;11) Leukemia Cells.

KMT2A FGFR2

9.60e-054140233924850
Pubmed

Quetiapine and aripiprazole signal differently to ERK, p90RSK and c-Fos in mouse frontal cortex and striatum: role of the EGF receptor.

FOS EGFR

9.60e-054140224552586
Pubmed

Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta.

FOS SOS2

9.60e-05414029058381
Pubmed

Glycosylation Changes in Serum Proteins Identify Patients with Pancreatic Cancer.

CEP350 LIFR

9.60e-054140228244758
Pubmed

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.

EGFR TARBP2

9.60e-054140223636329
Pubmed

beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits.

ADD1 ADD3

9.60e-054140219900187
Pubmed

EGF-responsive neural stem cells are a transient population in the developing mouse spinal cord.

EGFR FGFR2

9.60e-054140211553295
Pubmed

The role of Dicer protein partners in the processing of microRNA precursors.

RBBP6 TARBP2

9.60e-054140222163034
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ARHGAP32 IRS4 ZDHHC5 KIAA1549 NUP155 SMG7 PRRC2B

9.97e-05263140734702444
Pubmed

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.

SYNRG ARHGAP32 VPS37A EGFR

1.03e-0460140434761192
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

RBBP6 SIPA1L3 CEP350 PRR12 SMG7 ZNF592

1.05e-04184140632908313
GeneFamilySterile alpha motif domain containing

SAMD9 BICC1 EPHA4 EPHB1

8.57e-0488874760
GeneFamilyReceptor Tyrosine Kinases|CD molecules

LMTK2 ROS1 FGFR2

9.35e-0440873321
GeneFamilyFibronectin type III domain containing

MYBPH LIFR ROS1 EPHA4 EPHB1

1.05e-03160875555
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA4 EPHB1

2.01e-03148721095
GeneFamilyATPase phospholipid transporting

ATP8B1 ATP10A

2.31e-03158721210
GeneFamilySulfatases

ARSK ARSF

3.33e-0318872410
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 ARHGAP32 DYM ARHGEF28 SIPA1L3 ZNF407 RERE HERC1 TRAPPC9

1.35e-08199139994b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

STARD13 FOS AAK1 SYBU LIFR PDE4DIP RERE TRAPPC9

1.53e-071901398f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 OXR1 SIPA1L3 TOM1L1 LAMA1 FGFR2 RERE BICC1

1.94e-071961398eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SIPA1L3 VCAN PIP5K1B FGFR2 RERE STRA6 UNC79

2.13e-061881397b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

OXR1 ATP8B1 ATP10A ADD1 LIFR ART4 EPHA4

2.54e-0619313972531266bc57339d4e2b22a88817008e32b8c1598
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 OXR1 TOM1L1 LAMA1 FGFR2 SPAG17 BICC1

2.62e-06194139793c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 OXR1 SIPA1L3 TOM1L1 FGFR2 RERE BICC1

2.72e-0619513976477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 OXR1 SIPA1L3 TOM1L1 LAMA1 FGFR2 BICC1

2.81e-0619613976ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellControl-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

SH3TC2 FOS NOX4 ZFPM2 ADD3 VCAN BICC1

2.90e-06197139764cc5f61c88e9560b0f8f6f3151255dffb5c3d66
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 ARHGAP32 SIPA1L3 ZNF407 EGFR RERE TRAPPC9

3.00e-0619813971996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

AAK1 AKNA RNF213 ZNF407 JMY HERC1

1.63e-0517113962e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NBEAL1 TRPC4 ITGA8 ATP8B1 ATP10A PIP5K1B

2.11e-051791396111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

OXR1 LAMA1 CCNP PIP5K1B BICC1 EPHA4

2.25e-0518113969d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UNCX LAMA1 CCNP PIP5K1B BICC1 EPHA4

2.32e-051821396eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

ARHGEF28 NBEAL1 TRPC4 ITGA8 ATP10A PIP5K1B

2.39e-051831396818fd886e0188091310825f9145fa53328f2c979
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UNCX OXR1 CCNP FGFR2 BICC1 EPHA4

2.39e-051831396cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

SIPA1L3 TNRC18 PIP5K1B MPHOSPH9 RERE TRAPPC9

2.62e-051861396de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SIPA1L3 TNRC18 PIP5K1B MPHOSPH9 RERE TRAPPC9

2.62e-0518613960b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

OXR1 NBEAL1 RBBP6 ADD3 CEP350 VPS13D

2.62e-05186139603db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 KIAA1549 ATP10A SSC5D PIP5K1B

2.70e-05187139615d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 KIAA1549 ATP10A SSC5D PIP5K1B

2.70e-051871396f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

NOX4 SLC40A1 ZFPM2 SSC5D VCAN BICC1

2.70e-051871396a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 KIAA1549 ATP10A SSC5D PIP5K1B

2.78e-05188139632f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ARHGEF28 NBEAL1 TRPC4 ITGA8 ATP8B1 ATP10A

2.87e-0518913966b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

OXR1 FOS ITGA8 ATP8B1 ART4 VCAN

2.87e-05189139675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

SH3TC2 AAK1 ADD1 LIFR EGFR EPHA4

3.04e-051911396ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA8 SLC40A1 ZFPM2 LIFR BICC1 EPHB1

3.04e-051911396fa380a8752de158974b2ae5e741573439719cc0d
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADD3 EGFR VCAN FGFR2 BICC1 PLXNB1

3.13e-0519213960dc1f46e40346ed0b286e53b106a812441575100
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 OXR1 TOM1L1 FGFR2 BICC1 PLXNB1

3.32e-0519413965eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA8 SLC40A1 ZFPM2 LIFR VCAN BICC1

3.32e-0519413968c37bedb23285735ff3828db3889897fada8c95d
ToppCellIPF-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

SH3TC2 MASP1 FOS ATP8B1 LIFR NFE2L1

3.32e-051941396e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

NOX4 ZFPM2 ADD3 EGFR VCAN BICC1

3.32e-051941396234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 ATP10A ZFPM2 ART4 VCAN

3.42e-05195139649c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 ATP10A ZFPM2 ART4 VCAN

3.42e-051951396dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 SIPA1L3 ZNF407 PIP5K1B RERE TRAPPC9

3.52e-051961396ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MAGEA4 DIPK1C SAMD9 AAK1 AKNA RNF213

3.62e-0519713962e9677b4b9a7c88db16416e5f114a2031ec3bc24
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

DIPK1C FOS ADD3 EGFR KCNJ10 HADHB

3.62e-05197139658b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ITGA8 SLC40A1 ADD3 LIFR VCAN BICC1

3.62e-05197139611a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ITGA8 SLC40A1 ZFPM2 LIFR VCAN BICC1

3.72e-05198139617dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LAMA1 ITGA8 SLC40A1 LIFR VCAN BICC1

3.83e-051991396a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

OXR1 VPS13D VCAN KMT2A FGFR2 PLXNB1

3.83e-051991396174f6013af6eafa577f84205a62927f2b367fda3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

DIPK1C MASP1 FOS LIFR KCNJ10 HADHB

3.93e-052001396ed4a41cb6782541d8fc928aaa12cf03bc1c630a2
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ARHGEF28 TOM1L1 MUC16 ATP8B1 PIP5K1B

3.93e-0520013960eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

DIPK1C MASP1 FOS LIFR KCNJ10 HADHB

3.93e-052001396792fef1f3e47ce5c131fedfad55075fc254aeead
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD13 ARHGEF28 SLC22A15 CASP9 SLC40A1

6.13e-051331395f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD13 ARHGEF28 SLC22A15 CASP9 SLC40A1

6.13e-051331395292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte|GW09 / Sample Type, Dataset, Time_group, and Cell type.

LAMA1 CASP9 ZDBF2 BICC1 RABGGTA

8.36e-05142139585e573616e54d41391b4ad8c3d38e4ca92112673
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ITGA8 TTC7A RP1L1 LSM11 EPHB1

1.22e-041541395d22902d2922784583f7016453768ed05b14b965e
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TRIOBP KIAA1549 TTC7A ART4 KCNH2

1.51e-0416113958ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

KLF8 NBEAL1 ITGA8 ATP10A PIP5K1B

1.69e-041651395f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 ATP10A ART4 PIP5K1B

1.79e-041671395b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 ATP10A ART4 PIP5K1B

1.79e-04167139594fc7df7ca55cd722a8dbd153201a29891217473
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 ATP10A ART4 PIP5K1B

1.79e-041671395eff3723fe60755272eca237459165e436e919ece
ToppCellControl|World / group, cell type (main and fine annotations)

ARHGEF28 FOS EGFR PIP5K1B ROS1

1.84e-041681395a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KLF8 ARHGEF28 ITGA8 PKMYT1 TNRC18

1.84e-0416813958c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPC4 ZDBF2 KCNH2 PIP5K1B UNC79

1.94e-041701395941d637cf76918ee4b0a1833abd1a42593cb8b1a
ToppCellsevere_COVID-19-Neutrophil|severe_COVID-19 / disease group, cell group and cell class (v2)

SAMD9 FOS IER3 UNC79 EPHB1

2.05e-0417213958f4bcb9b2bbf8b4333f673d8ad6bb88dfda4792a
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

SAMD9 RNF213 ATP8B1 ATP10A PLXNB1

2.22e-041751395ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

SAMD9 RNF213 ATP8B1 ATP10A PLXNB1

2.22e-041751395ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EEF1AKMT4-ECE2 ITGA8 ATP10A ZFPM2 PIP5K1B

2.22e-041751395d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

FRMPD1 KCNH2 FMN2 UNC79 EPHB1

2.22e-0417513954db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EEF1AKMT4-ECE2 ITGA8 ATP10A ZFPM2 PIP5K1B

2.22e-041751395454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

FRMPD1 KCNH2 FMN2 UNC79 EPHB1

2.22e-0417513958d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MASP1 CCNP EGFR SPAG17 BICC1

2.28e-04176139533323c97afe509147956b8df9f92ca6b0537e604
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTC7A SSC5D TTC7B RP1L1 SOS2

2.28e-04176139576fdf211bce101e83a27d822cb399487bd107027
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA8 NOX4 ARSF EGFR VCAN

2.34e-04177139585e270b4a0b0da77ffe5987a099e827c02a4adf3
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JMY PKMYT1 IER3 KCNJ10 MPHOSPH9

2.34e-041771395f28243b51be104cb3adcde63f03fc2206ed3121e
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA8 LMTK2 ZDBF2 AASDH SH2D7

2.34e-0417713958abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

JMY VPS13D KCNJ10 KMT2A HERC1

2.34e-041771395e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DYM COG7 EIF2D ARSF

2.42e-04971394332b4daf5106872dd891d9f9b5a891192d5d9aa8
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA8 KIAA1549 ZFPM2 LONRF3 UNC79

2.46e-041791395b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 TOM1L1 SYBU GORASP1 GPAT2

2.46e-04179139588dbec952507d84b85b08165eec80df99ed1e736
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 TOM1L1 SYBU GORASP1 GPAT2

2.46e-041791395daf8189a22786171e2b629261cf720736aa4ebdb
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

ARHGEF28 MUC16 SYBU FGFR2 STRA6

2.46e-0417913951fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGEF28 ITGA8 NOX4 EGFR VCAN

2.46e-04179139501302505816f272243659e20d751b61a198a2fc0
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

MASP1 TRPC4 ITGA8 SLC40A1 VCAN

2.53e-041801395137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

MASP1 TRPC4 ITGA8 SLC40A1 VCAN

2.53e-041801395cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 OXR1 ATP10A EGFR BICC1

2.66e-0418213955e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGEF28 TRPC4 ARSF EGFR VCAN

2.66e-041821395724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LIFR EGFR PIP5K1B ROS1 FGFR2

2.73e-0418313956847c1252d6bb105524f812658112517fd351eab
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

SAMD9 RBBP6 RNF213 CEP350 IER3

2.73e-0418313958f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

ARHGEF28 MUC16 ATP8B1 SYBU FGFR2

2.73e-041831395940cbe298e9c53b5622af09264586ed823d3141f
ToppCellIPF-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

SH3TC2 MUC16 ZFPM2 EGFR BICC1

2.73e-0418313957df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ARHGEF28 NBEAL1 TRPC4 ITGA8 ATP10A

2.73e-041831395cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

DIPK1C ITGA8 SSC5D ZNF469 STRA6

2.80e-0418413950b336489c10e8c3c957795dd845454f03404382b
ToppCelldroplet-Heart-HEART-1m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIPA1L3 ZNF280C VPS13D EPHB1

2.82e-0410113946c4524be89cf3eb06769c2963dcded3da1e71ca0
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

MASP1 NOX4 ZFPM2 SSC5D BICC1

2.87e-041851395fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SH3TC2 OXR1 LIFR EGFR BICC1

2.94e-0418613955c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellDendritic_Cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

DIPK1C FOS PKMYT1 IER3 VCAN

2.94e-0418613951d52912bd17e232cf39b2423a4d93585c164ba34
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

OXR1 SIPA1L3 NOX4 FGFR2 BICC1

2.94e-041861395b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP32 ARHGEF28 EGFR ROS1 FGFR2

2.94e-041861395e83718fabb057100835d3357df407f283d23fe16
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRPC4 ZDBF2 MTRNR2L6 ART4 BICC1

3.01e-04187139576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SH3TC2 VCAN KCNJ10 FGFR2 PLXNB1

3.01e-04187139597e520705491c8f52a32025311a9fa7b9176979a
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

STARD13 PIP5K1B ROS1 LONRF3 EPHA4

3.01e-041871395030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNCX CCNP EGFR VCAN BICC1

3.01e-0418713959225caf66e06ebe57e90d677122acb6498607f36
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SH3TC2 VCAN KCNJ10 FGFR2 PLXNB1

3.09e-04188139560242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC4 ITGA8 ATP10A ZFPM2 PIP5K1B

3.09e-041881395b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZDBF2 ZFPM2 EIF2D KMT2A BICC1

3.09e-0418813956468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZDBF2 ZFPM2 EIF2D KMT2A BICC1

3.09e-0418813957a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

ARHGEF28 NBEAL1 TRPC4 ITGA8 ATP10A

3.09e-04188139534e1b074a3995aa46ab194eb45115d76d1a5514d
Drugimatinib

TOM1L1 LAMA1 CASP9 ADD3 PKMYT1 LIFR EGFR PDE4DIP ROS1 FGFR2 RERE EPHA4 EPHB1

2.08e-0643013713CID000005291
Drugmethyl ethyl ketone

MASP1 FOS TOM1L1 LAMA1 CASP9 ART4 EGFR IER3 GORASP1 FGFR2 HADHB SPAG17 EPHA4 EPHB1 SOS2

2.65e-0658713715CID000006569
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; HL60; HG-U133A

AAK1 MAST2 ADD1 VPS13D SMG7 BAZ2A MPHOSPH9 TRAPPC9 SOS2

3.00e-0619613792005_DN
Drug2-propylpentanoic acid; Down 200; 50uM; HL60; HT_HG-U133A

ARHGAP32 FRMPD1 AP3B1 SBNO2 DZANK1 FGFR2 RERE LONRF3 SOS2

3.39e-0619913792682_DN
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; HL60; HT_HG-U133A

ARHGAP32 SIPA1L3 TUT1 MAST2 SBNO2 VPS13D SMG7 JHY SOS2

3.39e-0619913796148_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

RBBP6 PPRC1 SIPA1L3 TRIOBP ANKZF1 SMG7 ZNF592 BAZ2A

2.18e-0519213786986_DN
DrugAmprolium hydrochloride [137-88-2]; Down 200; 12.6uM; PC3; HT_HG-U133A

FRMPD1 AAK1 TUT1 SBNO2 OSBP2 FGFR2 TRAPPC9 PLXNB1

2.27e-0519313784241_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A

SH3TC2 DNAJC13 PPRC1 MAST2 BAZ2A KMT2A BICRAL EPHA4

2.35e-0519413784524_DN
DrugPergolide mesylate [66104-23-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A

AAK1 ZNF407 ANKZF1 CEP350 KMT2A BICRAL FGFR2 RERE

2.44e-0519513787434_UP
DrugIsoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A

STARD13 TRIOBP ANKZF1 SMG7 KMT2A MPHOSPH9 HERC1 LONRF3

2.53e-0519613782056_DN
DrugSuxibuzone [27470-51-5]; Down 200; 9.2uM; PC3; HT_HG-U133A

SAMD9 MAST2 VPS13D SMG7 BAZ2A KMT2A LONRF3 PRRC2B

2.53e-0519613785806_DN
DrugMeptazinol hydrochloride [59263-76-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A

ARHGAP32 SAMD9 CASP9 MAST2 ANKZF1 VPS13D SMG7 BAZ2A

2.63e-0519713784774_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

STARD13 AAK1 TRIOBP CASP9 ANKZF1 VPS13D EGFR BAZ2A

2.63e-0519713786222_DN
Drugfluphenazine dihydrochloride; Up 200; 10uM; PC3; HT_HG-U133A

FOS TUT1 MAST2 ANKZF1 OSBP2 BICC1 EPHA4 EPHB1

2.63e-0519713781237_UP
DrugAcenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A

SIPA1L3 SYBU DZANK1 SMG7 KMT2A FGFR2 JHY SOS2

2.72e-0519813787232_UP
DrugGlycopyrrolate [596-51-0]; Down 200; 10uM; MCF7; HT_HG-U133A

MAST2 SBNO2 SMG7 BAZ2A KCNH2 PDE4DIP RERE TRAPPC9

2.72e-0519813783427_DN
DrugSulfisoxazole [127-69-5]; Down 200; 15uM; PC3; HT_HG-U133A

ARHGAP32 FRMPD1 VPS13D SMG7 VCAN RERE JHY SOS2

2.72e-0519813784661_DN
DrugVinpocetine [42971-09-5]; Down 200; 11.4uM; PC3; HT_HG-U133A

SIPA1L3 TUT1 VPS13D ZNF592 BAZ2A MPHOSPH9 RABGGTA PRRC2B

2.82e-0519913785859_DN
DrugMeropenem [96036-03-2]; Down 200; 10.4uM; PC3; HT_HG-U133A

SAMD9 ATP8B1 AP3B1 MAST2 ANKZF1 ADD1 CEP350 SMG7

2.82e-0519913785824_DN
Drugsodium 4-phenylbutyrate; Down 200; 1000uM; MCF7; HG-U133A

ARHGAP32 CCNP TUT1 SBNO2 VPS13D RERE PRRC2B EPHA4

2.82e-051991378408_DN
DrugAcyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HG-U133A

RBBP6 SIPA1L3 CCNP AAK1 ADD1 KMT2A MPHOSPH9 HERC1

2.82e-0519913781960_DN
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A

IRS4 CCNP ZNF407 RNF17 PDE4DIP VRTN TRAPPC9 EPHB1

2.93e-0520013783714_UP
Drugtrioctyltrimellitate

ART4 POLK

3.59e-0521372CID000006960
DrugAC1NST48

SYNRG DNAJC13 DYM COG7 CASP9 SYBU AP3B1 ART4 EGFR KCNH2 GORASP1 VCAN HERC1

6.34e-0559413713CID005315496
Drugsilicon;titanium

ARHGAP32 DYM

1.07e-0431372CID006336553
DrugFD137 nitrosourea

FOS EGFR

1.07e-0431372ctd:C471268
DrugDETA/NO

FOS CASP9 NOX4 NEUROG1 GORASP1

1.23e-04801375CID000004518
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

ZNF407 RNF17 ATP10A KCNH2 PDE4DIP FGFR2 PLXNB1

1.51e-0418913775586_UP
DrugKetanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; PC3; HT_HG-U133A

CEP350 SMG7 EGFR BAZ2A VCAN PDE4DIP KMT2A

1.51e-0418913776649_DN
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

STARD13 SIPA1L3 LMTK2 ADD3 EGFR PDE4DIP FGFR2

1.56e-0419013772375_UP
DrugButamben [94-25-7]; Down 200; 20.6uM; PC3; HT_HG-U133A

SH3TC2 ARHGEF28 EGFR PDE4DIP BICC1 PRRC2B SOS2

1.61e-0419113775792_DN
Drugnaphtho(1,2-b)furan-4,5-dione

FOS CASP9 EGFR

1.63e-04181373ctd:C073873
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; PC3; HT_HG-U133A

SAMD9 FRMPD1 TUT1 MAST2 VCAN FGFR2 PLXNB1

1.71e-0419313774226_DN
DrugMetanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; PC3; HT_HG-U133A

SIPA1L3 SBNO2 SMG7 EGFR PDE4DIP PLXNB1 SOS2

1.71e-0419313776734_DN
DrugDiphenidol hydrochloride [3254-89-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A

SYNRG TRIOBP ANKZF1 VPS13D BAZ2A FGFR2 SOS2

1.71e-0419313777447_DN
DrugDipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A

SIPA1L3 MAST2 CEP350 PDE4DIP FGFR2 PLXNB1 SOS2

1.83e-0419513773835_DN
DrugPerphenazine [58-39-9]; Down 200; 10uM; PC3; HG-U133A

RBBP6 PPRC1 SIPA1L3 CCNP ATP8B1 ZNF592 BAZ2A

1.83e-0419513771956_DN
DrugCalycanthine [595-05-1]; Down 200; 11.6uM; PC3; HT_HG-U133A

SIPA1L3 TRIOBP VPS13D BAZ2A KCNH2 VCAN EPHA4

1.83e-0419513775744_DN
DrugEthopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; HL60; HT_HG-U133A

ZNF407 ART4 BAZ2A PDE4DIP STRA6 PLXNB1 EPHB1

1.83e-0419513773038_UP
DrugPyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A

SIPA1L3 ITGA8 KMT2A OSBP2 FGFR2 RERE SOS2

1.83e-0419513772260_UP
DrugTrimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A

ZNF407 VPS13D SMG7 BAZ2A FGFR2 BICC1 PLXNB1

1.89e-0419613774100_DN
DrugProstaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A

SH3TC2 SAMD9 TRIOBP AP3B1 PKMYT1 CEP350 BAZ2A

1.89e-0419613776571_DN
DrugSulfadoxine [2447-57-6]; Up 200; 12.8uM; PC3; HT_HG-U133A

SAMD9 ATP10A LIFR VCAN PDE4DIP EPHB1 SOS2

1.89e-0419613775852_UP
DrugMifepristone [84371-65-3]; Down 200; 9.4uM; PC3; HT_HG-U133A

STARD13 ARHGAP32 ARHGEF28 VPS13D VCAN PRRC2B JHY

1.89e-0419613775827_DN
DrugSeneciphylline [480-81-9]; Down 200; 12uM; PC3; HT_HG-U133A

FRMPD1 SBNO2 SMG7 OSBP2 FGFR2 RERE PLXNB1

1.89e-0419613774238_DN
DrugCorynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; PC3; HT_HG-U133A

TUT1 SBNO2 VCAN FGFR2 RERE PLXNB1 JHY

1.89e-0419613774227_DN
DrugMebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; HL60; HT_HG-U133A

MAST2 ADD1 VPS13D SMG7 VCAN BICRAL SOS2

1.89e-0419613771333_UP
DrugHydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A

SYNRG TRIOBP VPS13D KCNH2 PDE4DIP TRAPPC9 SOS2

1.95e-0419713772765_DN
Drugarachidonic acid sodium salt; Down 200; 10uM; MCF7; HG-U133A

SYNRG MASP1 IRS4 AP3B1 VPS13D BAZ2A KMT2A

1.95e-041971377441_DN
DrugChloroquine diphosphate [50-63-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

SYBU ANKZF1 ADD1 SMG7 FGFR2 TRAPPC9 SOS2

1.95e-0419713777012_DN
DrugEsculin Hydrate [531-75-9]; Up 200; 11.8uM; PC3; HT_HG-U133A

SBNO2 VPS13D EGFR BAZ2A PDE4DIP RABGGTA SOS2

1.95e-0419713776310_UP
DrugCGX 0596987; Down 200; 20uM; PC3; HT_HG-U133A

SIPA1L3 ATP10A SMG7 EGFR PDE4DIP PIP5K1B SOS2

1.95e-0419713776369_DN
Drug3-nitropropionic acid; Down 200; 10uM; PC3; HT_HG-U133A

ATP10A SMG7 EGFR PDE4DIP KMT2A PIP5K1B SOS2

1.95e-0419713776372_DN
DrugNimesulide [51803-78-2]; Down 200; 13uM; HL60; HG-U133A

ATP8B1 MAST2 VPS13D SMG7 NFE2L1 MPHOSPH9 PRRC2B

2.01e-0419813771428_DN
Drugrofecoxib; Down 200; 10uM; MCF7; HG-U133A

CASP9 ATP8B1 MAST2 EGFR BAZ2A FGFR2 EPHB1

2.01e-041981377251_DN
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A_EA

AAK1 TRIOBP ATP8B1 ADD3 SMG7 BAZ2A TRAPPC9

2.01e-0419813771082_DN
DrugTheobromine [83-67-0]; Down 200; 22.2uM; HL60; HT_HG-U133A

SIPA1L3 TRPC4 ZNF407 SBNO2 PDE4DIP OSBP2 FGFR2

2.01e-0419813772995_DN
DrugMeclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; HL60; HT_HG-U133A

SIPA1L3 ZFPM2 VPS13D SMG7 PDE4DIP FGFR2 EPHB1

2.01e-0419813772424_UP
DrugNafcillin sodium salt monohydrate [7177-50-6]; Up 200; 8.8uM; MCF7; HT_HG-U133A

FRMPD1 VPS13D VCAN MPHOSPH9 RERE EPHB1 SOS2

2.01e-0419813774103_UP
DrugReserpine [50-55-5]; Down 200; 6.6uM; PC3; HT_HG-U133A

FRMPD1 TUT1 EGFR VCAN FGFR2 RERE SOS2

2.01e-0419813774203_DN
DrugSertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A

SAMD9 CCNP MAST2 ANKZF1 PDE4DIP OSBP2 SOS2

2.01e-0419813773550_UP
DrugFuraltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A

TRIOBP MAST2 BAZ2A PDE4DIP RERE PRRC2B JHY

2.01e-0419813773756_DN
DrugHeptaminol hydrochloride [543-15-7]; Up 200; 22uM; PC3; HT_HG-U133A

SIPA1L3 FRMPD1 SBNO2 OSBP2 RERE LONRF3 SOS2

2.01e-0419813777313_UP
DrugIoversol [87771-40-2]; Up 200; 5uM; MCF7; HT_HG-U133A

SYNRG SAMD9 CASP9 SYBU SMG7 PDE4DIP FGFR2

2.01e-0419813775326_UP
DrugIopamidol [60166-93-0]; Down 200; 5.2uM; PC3; HT_HG-U133A

SH3TC2 AP3B1 CEP350 VPS13D FGFR2 TRAPPC9 PRRC2B

2.07e-0419913775832_DN
DrugTriamcinolone [124-94-7]; Down 200; 10.2uM; MCF7; HT_HG-U133A

ARHGAP32 SIPA1L3 ANKZF1 SBNO2 KMT2A PLXNB1 PRRC2B

2.07e-0419913777192_DN
DrugGlimepiride [93479-97-1]; Up 200; 8.2uM; MCF7; HT_HG-U133A

ARHGEF28 ITGA8 BAZ2A KCNH2 VCAN KMT2A PLXNB1

2.07e-0419913774973_UP
DrugNisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A

ITGA8 CASP9 BAZ2A LONRF3 PLXNB1 JHY SOS2

2.07e-0419913775516_UP
DrugNalidixic acid sodium salt hydrate; Down 200; 14.6uM; MCF7; HT_HG-U133A

SIPA1L3 TRIOBP ANKZF1 SBNO2 SMG7 BAZ2A SOS2

2.07e-0419913774691_DN
DrugMethoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; PC3; HT_HG-U133A

AAK1 ATP8B1 ANKZF1 ADD1 MAP7D1 PRRC2B JHY

2.07e-0419913776355_DN
DrugUrapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; MCF7; HT_HG-U133A

SYNRG ARHGAP32 SIPA1L3 AP3B1 SBNO2 DZANK1 KMT2A

2.07e-0419913775295_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A

AAK1 SBNO2 BAZ2A RERE STRA6 LONRF3 PLXNB1

2.07e-0419913774346_DN
Drughaloperidol; Down 200; 10uM; MCF7; HT_HG-U133A

DNAJC13 AAK1 AP3B1 VPS13D ZNF592 MPHOSPH9 RERE

2.07e-0419913776923_DN
Drugprednisolone; Up 200; 1uM; MCF7; HG-U133A

ARHGEF28 ANKZF1 SBNO2 PDE4DIP BICRAL MPHOSPH9 FGFR2

2.07e-041991377265_UP
DrugDimaprit dihydrochloride [23256-33-9]; Down 200; 17uM; MCF7; HT_HG-U133A

CASP9 AP3B1 DZANK1 KCNH2 TRAPPC9 PLXNB1 SOS2

2.13e-0420013776520_DN
DrugDiflorasone Diacetate [33564-31-7]; Down 200; 8uM; PC3; HT_HG-U133A

ZNF407 AP3B1 PDE4DIP OSBP2 FGFR2 PLXNB1 SOS2

2.13e-0420013774077_DN
DrugSulfathiazole [72-14-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A

IRS4 SIPA1L3 ZNF592 KCNH2 VCAN FGFR2 SOS2

2.13e-0420013774769_UP
DrugCefotetan [69712-56-7]; Down 200; 7uM; PC3; HT_HG-U133A

FRMPD1 SBNO2 DZANK1 BAZ2A OSBP2 TRAPPC9 SOS2

2.13e-0420013773997_DN
DrugEpiandrosterone [481-29-8]; Down 200; 13.8uM; MCF7; HT_HG-U133A

CASP9 ANKZF1 PDE4DIP BICRAL FGFR2 LONRF3 SOS2

2.13e-0420013775687_DN
Diseasecortical surface area measurement

DNAJC13 SAMD9 PCNX3 NBEAL1 TRIOBP SYBU MAST2 PKMYT1 ZNF469 EGFR VCAN RP1L1 MPHOSPH9 FGFR2 RERE SPAG17 EPHA4 EPHB1 SOS2

1.11e-05134513419EFO_0010736
Diseasespastic quadriplegic cerebral palsy 3 (implicated_via_orthology)

ADD1 ADD3

6.12e-0531342DOID:0081361 (implicated_via_orthology)
Diseaseuric acid measurement

DNAJC13 UNCX PCNX3 SIPA1L3 AAK1 ZDHHC5 LMTK2 PIP5K1B BICC1 PRRC2B SOS2

1.12e-0461013411EFO_0004761
DiseaseEndometrial adenocarcinoma

EGFR FGFR2

1.22e-0441342C1153706
Diseasecortical thickness

NBEAL1 LAMA1 TRIOBP SYBU MAST2 ZNF469 VPS13D SMG7 EGFR VCAN FMN2 KMT2A RERE EPHA4 SOS2

1.68e-04111313415EFO_0004840
Diseaseurate measurement

DNAJC13 UNCX PCNX3 AAK1 LMTK2 CASP9 TTC7A FMN2 PIP5K1B BICC1 PRRC2B EPHA4 SOS2

2.28e-0489513413EFO_0004531
Diseasehearing loss

ARHGEF28 TRIOBP NOX4 MAST2

2.50e-04671344EFO_0004238
Diseaseneuroticism measurement

KLF8 OXR1 NBEAL1 ZDHHC5 LMTK2 DCAF8L1 RP1L1 KMT2A RERE HERC1 CMTR2 EPHA4 EPHB1

2.64e-0490913413EFO_0007660
Diseaseheparan sulfate glucosamine 3-O-sulfotransferase 3A1 measurement

ZFPM2 ADD3

3.03e-0461342EFO_0801671
Diseasehematocrit

STARD13 DNAJC13 UNCX NBEAL1 AAK1 ATP8B1 MAST2 SLC40A1 ZFPM2 PRR12 DZANK1 NFE2L1 BICC1

7.19e-04101113413EFO_0004348
DiseaseQT interval

ARHGEF28 MAST2 ZFPM2 TTC7B ZNF592 KCNH2 ROS1 NEURL4 PRRC2B

7.70e-045341349EFO_0004682
Diseasecerebral palsy (implicated_via_orthology)

ADD1 ADD3

8.99e-04101342DOID:1969 (implicated_via_orthology)
Disease4-vinylphenol sulfate measurement

EPHB1 SOS2

8.99e-04101342EFO_0021149
DiseaseHead and Neck Carcinoma

EGFR FGFR2

8.99e-04101342C3887461
Diseasecomplement factor H-related protein 3 measurement

VPS37A AAK1 LIFR SSC5D EPHA4

1.07e-031691345EFO_0600056
Diseaseschizophrenia, anorexia nervosa

ZNF592 MPHOSPH9 RERE

1.36e-03481343MONDO_0005090, MONDO_0005351
Diseaserestless legs syndrome

UNCX SLC40A1 PKMYT1

1.45e-03491343EFO_0004270
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

CASP9 KCNJ10

1.55e-03131342DOID:332 (biomarker_via_orthology)
DiseaseSkin Abnormalities

ZNF469 FGFR2

1.55e-03131342C0037268
Diseaseresponse to simvastatin, total cholesterol change measurement, response to fenofibrate

COG7 TRIOBP BICC1

1.63e-03511343EFO_0007806, GO_1901557, GO_1903491
Diseaseautosomal dominant polycystic kidney disease (is_marker_for)

FOS ITGA8

1.80e-03141342DOID:898 (is_marker_for)
Diseaseopen-angle glaucoma

TRIOBP ZFPM2 KMT2A RERE BICC1

1.84e-031911345EFO_0004190
DiseaseSmall cell carcinoma of lung

ZDBF2 EGFR KMT2A

1.92e-03541343C0149925
Diseasecreatinine measurement

KLF8 DNAJC13 UNCX SIPA1L3 CCNP CASP9 MAST2 SBNO2 ZNF592 NFE2L1 PIP5K1B SOS2

1.97e-0399513412EFO_0004518
Diseasecreatinine measurement, glomerular filtration rate

UNCX SIPA1L3 CASP9 PIP5K1B

2.03e-031171344EFO_0004518, EFO_0005208
DiseaseProstatic Neoplasms

SAMD9 TOM1L1 LMTK2 CASP9 LIFR EGFR BAZ2A KMT2A POLK

2.06e-036161349C0033578
DiseaseMalignant neoplasm of prostate

SAMD9 TOM1L1 LMTK2 CASP9 LIFR EGFR BAZ2A KMT2A POLK

2.06e-036161349C0376358
Diseasecochlin measurement

ZFPM2 NFE2L1

2.36e-03161342EFO_0801481
Diseasep-cresol sulfate measurement

STARD13 EPHA4

2.36e-03161342EFO_0010998
Diseasesmoking status measurement

SAMD9 TRPC4 LMTK2 ZNF407 MAST2 ADD1 ADD3 BICRAL RERE HERC1 UNC79 PRRC2B EPHB1

2.45e-03116013413EFO_0006527
Diseasebody surface area

EEF1AKMT4-ECE2 DYM UNCX AAK1 AP3B1 MAP7D1 KCNH2 UNC79 EPHA4

2.74e-036431349EFO_0022196
Diseasehypertension (implicated_via_orthology)

MYBPH NOX4 ADD1 ADD3

2.81e-031281344DOID:10763 (implicated_via_orthology)
Diseasecentral corneal thickness

MASP1 SAMD9 ZNF407 ZNF469 KMT2A BICC1

2.94e-033091346EFO_0005213
Diseasetransitional cell carcinoma (is_marker_for)

DAXX EGFR FGFR2

2.98e-03631343DOID:2671 (is_marker_for)
DiseaseAdrenocortical carcinoma

DAXX EGFR

2.99e-03181342C0206686
DiseaseMalignant neoplasm of endometrium

EGFR FGFR2

2.99e-03181342C0007103
DiseaseCarcinoma in situ of endometrium

EGFR FGFR2

2.99e-03181342C0346191
Diseaseosteochondrodysplasia (is_implicated_in)

DYM LIFR

3.33e-03191342DOID:2256 (is_implicated_in)
Diseaseresponse to COVID-19 vaccine, SARS-CoV-2 neutralizing antibody measurement

LMTK2 EGFR

3.69e-03201342EFO_0803359, EFO_0803362
Diseasejuvenile dermatomyositis

SYBU GPAT2

3.69e-03201342EFO_0000557
Diseasestomach cancer (is_marker_for)

CASP9 DAXX FGFR2 EPHB1

4.07e-031421344DOID:10534 (is_marker_for)
DiseaseIntellectual Disability

KLF8 OXR1 LAMA1 RBM28 PRR12 FGFR2 STRA6

4.42e-034471347C3714756
Diseaseceramide measurement

STARD13 OXR1 ATP8B1 EIF2D OSBP2

4.46e-032351345EFO_0010222

Protein segments in the cluster

PeptideGeneStartEntry
LFDLSRDPSESTPLT

ARSF

506

P54793
LPQLFDLSSDPDELT

ARSK

436

Q6UWY0
PSIAPLALDSADLSE

EIF2D

186

P41214
TLTDELPAFSLTPLE

COG7

611

P83436
ILPFELESPNVATSS

VCAN

1751

P13611
ATPPFSLLETSNETD

VCAN

3056

P13611
LSNPTTDLLEEFAPT

AAK1

871

Q2M2I8
TDLLEEFAPTAISAP

AAK1

876

Q2M2I8
TAFSFEDDTVPLSPL

ADD3

411

Q9UEY8
TPILSEDSLEPFNSL

BAZ2A

291

Q9UIF9
QLASPASFSPDILAD

CMTR2

11

Q8IYT2
EDVLFLASPLTFDPS

AASDH

231

Q4L235
SPLQSLAASLDAEPS

CCNP

26

Q9H8S5
LESFPPSEARSALEN

PDSS2

376

Q86YH6
RLLSDPELSATESPL

BICC1

676

Q9H694
ELSPAVLDSLESPLF

CDAN1

346

Q8IWY9
SLLSEEPLAPSSIDA

DAXX

531

Q9UER7
FLAPELPAVSEFSTS

HADHB

206

P55084
DFVPADILLLSSSEP

ATP8B1

206

O43520
IFPADILLLSSSDPD

ATP10A

176

O60312
VSLLDLDDFNPVSTP

AP3B1

816

O00203
LLFSPEVESLPVASS

NFE2L1

376

Q14494
SLDSNTPLFPEDSSV

NBEAL1

1336

Q6ZS30
LPPSARSEQLEELFS

RBM28

11

Q9NW13
ESSLFSTLTPPDDQI

KIAA1549

801

Q9HCM3
PDFNISRAESLPLSS

ARHGEF28

526

Q8N1W1
FPETLPESSLFSVEA

C8orf76

216

Q96K31
PLLDRSIPDFTAFTT

EPHB1

901

P54762
ARPSFSLVEDTTLEP

FGFR2

21

P21802
VSSTLVEDFPSASLP

MUC16

8281

Q8WXI7
VEDFPSASLPVTSLL

MUC16

8286

Q8WXI7
FSCLLLPTSETDLPV

MTRNR2L6

6

P0CJ73
SAVLEPFNLTSEPSD

IER3

126

P46695
SPRLDVSSDSFDPLL

LSM11

21

P83369
PSTSPDAESLFREAL

MAGEA4

96

P43358
DTASDSPFLILPLTF

KCNJ10

241

P78508
ALPESTDSSLENLPL

JHY

146

Q6NUN7
DVLRESFTLLPDTDP

JMY

941

Q8N9B5
SFTLLPDTDPLTRSI

JMY

946

Q8N9B5
ALDALRSVLPSFPDD

NEUROG1

111

Q92886
ATPESEEAFTLPLLN

FOS

231

P01100
PSATEDSLQPATDLL

ZFPM2

401

Q8WW38
NEIASFSLDPTLPSV

HERC1

2461

Q15751
DPFLASPTSDREIIA

KCNH2

346

Q12809
ALLDPSSPEFSAVVS

EPHA4

901

P54764
PLDLSLSLSLSLSPD

PCNX3

1966

Q9H6A9
TDFRPSATPEDLLAS

PLXNB1

776

O43157
DLVPSTPSLFEAASL

PIP5K1B

461

O14986
LDDRISFSPDSVLEP

MPHOSPH9

316

Q99550
ASDFSLPQVEPVDLS

KLF8

76

O95600
DSLLEDSLSAPFPAS

LMTK2

976

Q8IWU2
SSNRLTTLPPDFLES

LRIT3

161

Q3SXY7
KLSPFFTLDLSPTED

ARHGAP32

861

A7KAX9
TTSSAPLALLPLDSF

OSBP2

171

Q969R2
LTLPDSLTSAASPED

GORASP1

386

Q9BQQ3
AASPEDTPELSAFLR

ITGA8

881

P53708
PSLLQFTFSEDDPIL

NUP155

266

O75694
FRDLLLPPSSQDSEI

NOX4

381

Q9NPH5
TDSLFVLPSRDDATP

RBBP6

971

Q7Z6E9
SESFRPNLSDPSELL

OXR1

701

Q8N573
SFLLSPLELSDSEPV

EEF1AKMT4-ECE2

466

P0DPD8
ALTEDSIDDTFLPVP

EGFR

1076

P00533
SLQFLEDELESSPLP

BICRAL

81

Q6AI39
FPAPTSSSELKLLEE

DYM

41

Q7RTS9
DAAPAPASISLFDLS

ANKZF1

6

Q9H8Y5
PASISLFDLSADAPV

ANKZF1

11

Q9H8Y5
SFPLVPSASLESVDD

FRMPD1

851

Q5SYB0
FDQLDAISSLPTPSD

CASP9

326

P55211
PLLFDDLPPASSTDS

ILKAP

26

Q9H0C8
LPPEASLSLDSSEGL

GPAT2

251

Q6NUI2
TLALLAFDSPEESPF

GID8

146

Q9NWU2
ESPSLASVPTADELF

CEP350

2481

Q5VT06
LSSESELPSLPLFSE

AKNA

1171

Q7Z591
TSDDLLFSKESPLLP

DNAJC13

1406

O75165
SRTPETLLPFAEAEA

MAP7D1

811

Q3KQU3
PTLRDSDLLSPSDFK

MASP1

501

P48740
AEFISSNTPDSVLPL

MAST2

336

Q6P0Q8
FELPLELPSDLSVLT

KMT2A

2921

Q03164
LPDLVTESLFSSPEE

DCAF8L1

11

A6NGE4
SLALAAEEPRPFSES

DZANK1

401

Q9NVP4
SPDTEQALSALSDLP

FMN2

266

Q9NZ56
LPETLNSPLLETFSD

SLC22A15

481

Q8IZD6
ENLSPFDSIPDSELL

PPRC1

141

Q5VV67
FDSIPDSELLVSPRE

PPRC1

146

Q5VV67
VTALDPSVLDFPSSA

NEURL4

106

Q96JN8
AFSSFPPLSLLEEEA

DIPK1C

121

Q0P6D2
PDTPEILNLSADFST

LIFR

136

P42702
SAFPTDSLERDLSPS

IRS4

1101

O14654
DSLERDLSPSSAPAV

IRS4

1106

O14654
LCDPAESELSPFLIT

TAS2R39

21

P59534
FPKALSIESLSPTDS

STARD13

406

Q9Y3M8
TTSEPSAPSQDLLDL

TOM1L1

306

O75674
TPPVSASSDLSVFLD

SOS2

1091

Q07890
VSEDALPETTFPALA

SYNRG

951

Q9UMZ2
LSSVDDPRDPLIETF

SAMD9

546

Q5K651
AAVPPAEELAFTDSL

RABGGTA

156

Q92696
PSADDLSPKLLEFTS

LAMA1

206

P25391
DLSSISATPLPEEFE

SMG7

406

Q92540
VSLFSLNDPALSPDI

SIPA1L3

1666

O60292
VDSLSDIVDTPDFLP

SBNO2

111

Q9Y2G9
LLSATSDSYRLPEPD

SH3TC2

431

Q8TF17
SPLDLSVSPFEDIRS

SLC40A1

396

Q9NP59
PSAPLLLTLDDVSSS

MYBPH

71

Q13203
RPPSSEFLDLSSASE

RERE

476

Q9P2R6
ESISSAISALDDPPL

PRR12

1396

Q9ULL5
DLILTSPDFALSTPD

SSC5D

1061

A1L4H1
FPLPSSDLDDSLTEE

MSANTD4

96

Q8NCY6
EPSLLFQDLPRASTE

TRIOBP

1131

Q9H2D6
EDALPFLTLASAPSQ

STRA6

121

Q9BX79
IADLTPLLSFQATDP

SPAG17

1411

Q6Q759
DSDAATFKPTLPDLS

ADD1

631

P35611
FEELLSAETDTPLLP

RNF17

1386

Q9BXT8
LTALPDEFSPAVSQA

RNF213

4036

Q63HN8
ASSDQFLPSLEDPLA

TNRC18

1326

O15417
SRTTELPAADPFALA

nan

331

Q6ZSR9
LGPLSFTLEDEPALS

RP1L1

1626

Q8IWN7
PSFEPRNLLSLFEDT

PKMYT1

481

Q99640
SFPESLSALVVDLTP

SYBU

531

Q9NX95
TEPLLSFVASVSPAD

TUT1

826

Q9H6E5
SPDLITTLADLFSPS

SPATA31D1

201

Q6ZQQ2
DLLAAFDIPDPTSLD

ZNF592

11

Q92610
RSISPLLFEESPSDV

POLK

246

Q9UBT6
SSSELTFDSDPPLLS

ZDBF2

746

Q9HCK1
TFDSDPPLLSVTEQS

ZDBF2

751

Q9HCK1
RFSLEDPTPDIILSS

MYCBPAP

881

Q8TBZ2
SSRLLSFSPEEFPTL

PRRC2B

161

Q5JSZ5
SPLPEKSSSLLEESF

SH2D7

221

A6NKC9
LENADLPTAPFASSI

ROS1

96

P08922
DSPSSLFESLISPIK

RIOX2

36

Q8IUF8
DILLASPSSAFQPDT

SKOR2

11

Q2VWA4
TLESSSLFPDLPVDR

ZNF469

1421

Q96JG9
DSLLTPSDSPDFESV

ZDHHC5

471

Q9C0B5
FLTALELEASSPAVP

TTC7B

821

Q86TV6
FLTALELEASSPVLP

TTC7A

836

Q9ULT0
EFESLPAALSLPAES

TRAPPC9

626

Q96Q05
SILLFDSTQESLPPS

ZNF280C

141

Q8ND82
LEPALEDSSSFSPLD

TARBP2

101

Q15633
DSPFTAAALAEEPLV

ZNF407

1831

Q9C0G0
TSLPPATLEAIFDAD

VRTN

146

Q9H8Y1
EDFPLRLESAAPSQT

TRBV6-9

91

A0A0J9YX75
PSLIALSSEDPFLTA

TRPC4

206

Q9UBN4
DVPDAFPELSELSVS

VPS37A

226

Q8NEZ2
PGSPLLFDSTLDLET

TTF2

366

Q9UNY4
LPKASPFSVESLLSD

UNCX

326

A6NJT0
TSDSDSLVFEPLPPL

UNC79

1626

Q9P2D8
PIERESELTFSLSPD

VPS13D

1501

Q5THJ4
PALSLPLASFDASDL

LONRF3

451

Q496Y0
IPDPIAIASLSFLTS

ART4

291

Q93070
PPASTATLLSNDLEA

PDE4DIP

1761

Q5VU43