Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of skin epidermis	KRT6A KRT6B KRT6C	1.24e-04	43	45	3	GO:0030280
GeneOntologyMolecularFunction	1-phosphatidylinositol-4-phosphate 5-kinase activity	PIP5K1A PIP5K1C	1.77e-04	9	45	2	GO:0016308
GeneOntologyMolecularFunction	oxidized purine DNA binding	BLM MSH3	2.21e-04	10	45	2	GO:0032357
GeneOntologyMolecularFunction	oxidized DNA binding	BLM MSH3	2.70e-04	11	45	2	GO:0032356
GeneOntologyBiologicalProcess	epidermal cell differentiation	TGFB2 PIP5K1A KRT6A KRT6B KRT6C PLS1	3.35e-05	284	45	6	GO:0009913
GeneOntologyBiologicalProcess	keratinocyte differentiation	TGFB2 PIP5K1A KRT6A KRT6B KRT6C	5.56e-05	189	45	5	GO:0030216
HumanPheno	Paronychia	BLM KRT6A KRT6B	2.39e-05	16	19	3	HP:0001818
HumanPheno	Regional abnormality of skin	BLM JARID2 KRT6A KRT6B ARID1B KAT6B KRT6C WDR37 ADGRG6	5.59e-05	541	19	9	HP:0011356
HumanPheno	Abnormality of the periungual region	BLM KRT6A KRT6B	6.48e-05	22	19	3	HP:0100803
HumanPheno	Eruptive vellus hair cyst	KRT6A KRT6B	7.87e-05	4	19	2	HP:0025248
HumanPheno	Steatocystoma multiplex	KRT6A KRT6B	7.87e-05	4	19	2	HP:0012035
HumanPheno	Linear arrays of macular hyperkeratoses in flexural areas	KRT6A KRT6B	1.31e-04	5	19	2	HP:0007490
HumanPheno	Hyperplastic callus formation	KRT6A KRT6B	1.31e-04	5	19	2	HP:0030268
HumanPheno	White lesion of the oral mucosa	KRT6A KRT6B KRT6C	1.36e-04	28	19	3	HP:0025125
HumanPheno	Oral leukoplakia	KRT6A KRT6B KRT6C	1.36e-04	28	19	3	HP:0002745
HumanPheno	Onychogryposis of toenails	KRT6A KRT6B	2.74e-04	7	19	2	HP:0008401
HumanPheno	Onychogryposis	KRT6A KRT6B	2.74e-04	7	19	2	HP:0001819
HumanPheno	Gray matter heterotopias	PLCH1 KAT6B CPLANE1	4.61e-04	42	19	3	HP:0002281
HumanPheno	Periventricular heterotopia	PLCH1 KAT6B CPLANE1	4.61e-04	42	19	3	HP:0007165
HumanPheno	Abnormal skin morphology of the palm	JARID2 KRT6A KRT6B ARID1B KAT6B KRT6C WDR37	4.67e-04	413	19	7	HP:0040211
HumanPheno	Onychogryposis of fingernail	KRT6A KRT6B	4.67e-04	9	19	2	HP:0040036
MousePheno	abnormal mismatch repair	EXO1 MSH3	5.06e-05	5	32	2	MP:0009797
MousePheno	lethality during fetal growth through weaning, complete penetrance	BLM TGFB2 JARID2 KRT6A KRT6B RICTOR ARID1B STXBP3 PIP5K1C NFAT5 VCAN	7.09e-05	1269	32	11	MP:0011111
MousePheno	abnormal filiform papillae morphology	KRT6A KRT6B	1.06e-04	7	32	2	MP:0000763
MousePheno	abnormal interventricular septum morphology	TGFB2 JARID2 CPLANE1 PIP5K1C VCAN ADGRG6	1.09e-04	342	32	6	MP:0000281
MousePheno	abnormal renal tubule epithelium morphology	TGFB2 CPLANE1 NFAT5	1.76e-04	48	32	3	MP:0009640
MousePheno	abnormal heart septum morphology	TGFB2 JARID2 CPLANE1 PIP5K1C VCAN ADGRG6	2.16e-04	388	32	6	MP:0006113
MousePheno	pulmonary artery hypoplasia	TGFB2 CPLANE1	2.76e-04	11	32	2	MP:0010460
MousePheno	edema	JARID2 RICTOR ARID1B CPLANE1 PIP5K1C NFAT5 ADGRG6	2.81e-04	581	32	7	MP:0001785
MousePheno	myocardial trabeculae hypoplasia	TGFB2 JARID2 ADGRG6	3.09e-04	58	32	3	MP:0010503
MousePheno	abnormal myocardial trabeculae morphology	TGFB2 JARID2 NFAT5 ADGRG6	3.10e-04	144	32	4	MP:0002189
MousePheno	abnormal kidney epithelium morphology	TGFB2 CPLANE1 NFAT5	3.58e-04	61	32	3	MP:0004967
MousePheno	abnormal heart right ventricle morphology	TGFB2 CPLANE1 PIP5K1C VCAN	4.21e-04	156	32	4	MP:0003920
MousePheno	abnormal myocardium compact layer morphology	JARID2 NFAT5 ADGRG6	4.73e-04	67	32	3	MP:0004056
MousePheno	abnormal hard palate morphology	TGFB2 KRT6A KRT6B	4.73e-04	67	32	3	MP:0003756
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	2.39e-05	24	44	3	IPR032444
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	2.39e-05	24	44	3	PF16208
Domain	Keratin_II	KRT6A KRT6B KRT6C	3.05e-05	26	44	3	IPR003054
Domain	PInositol-4-P-5-kinase	PIP5K1A PIP5K1C	1.13e-04	7	44	2	IPR023610
Domain	PIPKc	PIP5K1A PIP5K1C	1.51e-04	8	44	2	SM00330
Domain	-	PIP5K1A PIP5K1C	1.51e-04	8	44	2	3.30.800.10
Domain	PIP5K	PIP5K1A PIP5K1C	1.51e-04	8	44	2	PF01504
Domain	PIPK	PIP5K1A PIP5K1C	1.51e-04	8	44	2	PS51455
Domain	PInositol-4-P-5-kinase_N	PIP5K1A PIP5K1C	1.51e-04	8	44	2	IPR027484
Domain	PInositol-4-P-5-kinase_C	PIP5K1A PIP5K1C	1.51e-04	8	44	2	IPR027483
Domain	-	PIP5K1A PIP5K1C	1.51e-04	8	44	2	3.30.810.10
Domain	PInositol-4-P-5-kinase_core	PIP5K1A PIP5K1C	1.51e-04	8	44	2	IPR002498
Domain	Intermediate_filament_CS	KRT6A KRT6B KRT6C	4.39e-04	63	44	3	IPR018039
Domain	-	JARID2 ARID1B	5.59e-04	15	44	2	1.10.150.60
Domain	BRIGHT	JARID2 ARID1B	5.59e-04	15	44	2	SM00501
Domain	ARID_dom	JARID2 ARID1B	5.59e-04	15	44	2	IPR001606
Domain	ARID	JARID2 ARID1B	5.59e-04	15	44	2	PS51011
Domain	ARID	JARID2 ARID1B	5.59e-04	15	44	2	PF01388
Domain	Filament	KRT6A KRT6B KRT6C	6.23e-04	71	44	3	SM01391
Domain	IF	KRT6A KRT6B KRT6C	6.50e-04	72	44	3	PS00226
Domain	Filament	KRT6A KRT6B KRT6C	6.76e-04	73	44	3	PF00038
Domain	IF	KRT6A KRT6B KRT6C	7.61e-04	76	44	3	IPR001664
Domain	p53-like_TF_DNA-bd	MGA NFAT5	6.93e-03	53	44	2	IPR008967
Pathway	WP_PHOSPHOINOSITIDES_METABOLISM	PIP5K1A PLCH1 PIP5K1C	1.50e-04	49	30	3	M40046
Pathway	REACTOME_DISEASES_OF_DNA_REPAIR	BLM EXO1 MSH3	1.69e-04	51	30	3	M29854
Pathway	REACTOME_MISMATCH_REPAIR	EXO1 MSH3	4.52e-04	15	30	2	M27442
Pathway	REACTOME_MISMATCH_REPAIR	EXO1 MSH3	4.52e-04	15	30	2	MM15184
Pubmed	Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.	KRT6A KRT6B KRT6C	2.02e-09	3	45	3	29357356
Pubmed	Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.	KRT6A KRT6B KRT6C	2.02e-09	3	45	3	7543104
Pubmed	Pachyonychia Congenita	KRT6A KRT6B KRT6C	2.02e-08	5	45	3	20301457
Pubmed	Postnatal gene expression in the normal mouse cornea by SAGE.	KRT6A KRT6B F2RL1	7.29e-07	14	45	3	14744882
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AKAP6 SLTM PHTF2 RICTOR ARID1B ABCB7 CPLANE1 MGA NFAT5 VCAN	9.82e-07	1084	45	10	11544199
Pubmed	A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.	KRT6A KRT6B	1.64e-06	2	45	2	11118885
Pubmed	Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.	KRT6A KRT6B	1.64e-06	2	45	2	11489919
Pubmed	Delayed wound healing in keratin 6a knockout mice.	KRT6A KRT6B	1.64e-06	2	45	2	10866680
Pubmed	Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa.	KRT6A KRT6B	1.64e-06	2	45	2	10953016
Pubmed	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.	KRT6A KRT6B	1.64e-06	2	45	2	6207530
Pubmed	PI5KI-dependent signals are critical regulators of the cytolytic secretory pathway.	PIP5K1A PIP5K1C	1.64e-06	2	45	2	18073347
Pubmed	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.	KRT6A KRT6B	1.64e-06	2	45	2	10550543
Pubmed	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.	KRT6A KRT6B	1.64e-06	2	45	2	10550545
Pubmed	Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling.	PIP5K1A PIP5K1C	1.64e-06	2	45	2	12682053
Pubmed	Type I phosphotidylinosotol 4-phosphate 5-kinase γ regulates osteoclasts in a bifunctional manner.	PIP5K1A PIP5K1C	1.64e-06	2	45	2	23300084
Pubmed	The role of versican isoforms V0/V1 in glioma migration mediated by transforming growth factor-beta2.	TGFB2 VCAN	1.64e-06	2	45	2	17453002
Pubmed	Cytokeratins mediate epithelial innate defense through their antimicrobial properties.	KRT6A KRT6B	1.64e-06	2	45	2	23006328
Pubmed	Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair.	BLM EXO1	1.64e-06	2	45	2	18971343
Pubmed	PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions.	PIP5K1A PIP5K1C	1.64e-06	2	45	2	19889969
Pubmed	The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.	KRT6A KRT6B	1.64e-06	2	45	2	9790766
Pubmed	Type I Phosphatidylinositol-4-Phosphate 5-Kinases α and γ Play a Key Role in Targeting HIV-1 Pr55Gag to the Plasma Membrane.	PIP5K1A PIP5K1C	1.64e-06	2	45	2	32376619
Pubmed	Endothelial cell barrier impairment induced by glioblastomas and transforming growth factor beta2 involves matrix metalloproteinases and tight junction proteins.	TGFB2 VCAN	1.64e-06	2	45	2	18431253
Pubmed	Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.	PIP5K1A PIP5K1C	1.64e-06	2	45	2	19153220
Pubmed	Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma.	KRT6A KRT6C	1.64e-06	2	45	2	23662636
Pubmed	Delineation of WRN helicase function with EXO1 in the replicational stress response.	BLM EXO1	4.91e-06	3	45	2	20447876
Pubmed	Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles.	KRT6A KRT6B	4.91e-06	3	45	2	17170733
Pubmed	DNA repair and cell cycle checkpoint defects in a mouse model of 'BRCAness' are partially rescued by 53BP1 deletion.	BLM EXO1	4.91e-06	3	45	2	29620483
Pubmed	Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice.	KRT6A KRT6B	4.91e-06	3	45	2	15601842
Pubmed	Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.	KRT6A KRT6B	4.91e-06	3	45	2	17851587
Pubmed	Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.	KRT6A KRT6B	4.91e-06	3	45	2	29587848
Pubmed	A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.	KRT6A KRT6B	4.91e-06	3	45	2	14573483
Pubmed	A role for keratins in supporting mitochondrial organization and function in skin keratinocytes.	KRT6A KRT6B	4.91e-06	3	45	2	32213122
Pubmed	Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair.	KRT6A KRT6B	4.91e-06	3	45	2	14568992
Pubmed	Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42.	PIP5K1A PIP5K1C	4.91e-06	3	45	2	14681219
Pubmed	Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.	KRT6A KRT6B	4.91e-06	3	45	2	1713533
Pubmed	PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells.	PIP5K1A PIP5K1C	4.91e-06	3	45	2	23342003
Pubmed	CLIC1 recruits PIP5K1A/C to induce cell-matrix adhesions for tumor metastasis.	PIP5K1A PIP5K1C	4.91e-06	3	45	2	33079727
Pubmed	Phosphatidylinositol-4-phosphate 5-kinase isoforms exhibit acyl chain selectivity for both substrate and lipid activator.	PIP5K1A PIP5K1C	4.91e-06	3	45	2	22942276
Pubmed	RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.	KRT6A KRT6B ARID1B	7.22e-06	29	45	3	36800290
Pubmed	Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.	PIP5K1A PIP5K1C	9.81e-06	4	45	2	18188447
Pubmed	Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family.	PIP5K1A PIP5K1C	9.81e-06	4	45	2	9535851
Pubmed	Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431.	KRT6A KRT6C	9.81e-06	4	45	2	9054461
Pubmed	Association between genetic polymorphisms in DNA mismatch repair-related genes with risk and prognosis of head and neck squamous cell carcinoma.	EXO1 MSH3	9.81e-06	4	45	2	25598504
Pubmed	Keratin 6 regulates collective keratinocyte migration by altering cell-cell and cell-matrix adhesion.	KRT6A KRT6B	9.81e-06	4	45	2	30389720
Pubmed	A review of the clinical phenotype of 254 patients with genetically confirmed pachyonychia congenita.	KRT6A KRT6B	9.81e-06	4	45	2	22264670
Pubmed	RPA Phosphorylation Inhibits DNA Resection.	BLM EXO1	9.81e-06	4	45	2	31153714
Pubmed	Mouse models in preclinical studies for pachyonychia congenita.	KRT6A KRT6B	9.81e-06	4	45	2	16250208
Pubmed	Identification and characterization of a phosphoinositide phosphate kinase homolog.	PIP5K1A PIP5K1C	9.81e-06	4	45	2	14701839
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	EXO1 FSIP2 RICTOR STOX2 USP54 CRYBG3 PLCH1 FGD6	1.31e-05	861	45	8	36931259
Pubmed	The interaction of DNA mismatch repair proteins with human exonuclease I.	EXO1 MSH3	1.63e-05	5	45	2	11427529
Pubmed	Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12.	KRT6A KRT6B	1.63e-05	5	45	2	1713141
Pubmed	Airway hillocks are injury-resistant reservoirs of unique plastic stem cells.	KRT6A KRT6B	1.63e-05	5	45	2	38693267
Pubmed	The diagnostic utility of D2-40, calretinin, CK5/6, desmin and MOC-31 in the differentiation of mesothelioma from adenocarcinoma in pleural effusion cytology.	KRT6A KRT6B	1.63e-05	5	45	2	23075894
Pubmed	Hair follicle stem cells regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem cells.	KRT6A KRT6B	1.63e-05	5	45	2	31898934
Pubmed	Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair.	BLM EXO1	1.63e-05	5	45	2	19015241
Pubmed	Role for keratins 6 and 17 during wound closure in embryonic mouse skin.	KRT6A KRT6B	1.63e-05	5	45	2	12557214
Pubmed	The lipid kinase PIP5K1C regulates pain signaling and sensitization.	PIP5K1A PIP5K1C	1.63e-05	5	45	2	24853942
Pubmed	MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1.	EXO1 MSH3	1.63e-05	5	45	2	37140056
Pubmed	BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair.	BLM EXO1	2.45e-05	6	45	2	21325134
Pubmed	p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.	KRT6A KRT6B	2.45e-05	6	45	2	25383540
Pubmed	Phospholipase Cε hydrolyzes perinuclear phosphatidylinositol 4-phosphate to regulate cardiac hypertrophy.	AKAP6 PLCH1	2.45e-05	6	45	2	23540699
Pubmed	Keratin 6 is not essential for mammary gland development.	KRT6A KRT6B	2.45e-05	6	45	2	16790075
Pubmed	Rac controls PIP5K localisation and PtdIns(4,5)P₂ synthesis, which modulates vinculin localisation and neurite dynamics.	PIP5K1A PIP5K1C	2.45e-05	6	45	2	20841379
Pubmed	Phosphatidylinositol 4,5-bisphosphate regulates adipocyte actin dynamics and GLUT4 vesicle recycling.	PIP5K1A PIP5K1C	2.45e-05	6	45	2	15123724
Pubmed	Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse.	KRT6A KRT6B	2.45e-05	6	45	2	16239341
Pubmed	Long noncoding RNA FTX promotes epithelial-mesenchymal transition of epithelial ovarian cancer through modulating miR-7515/TPD52 and activating Met/Akt/mTOR.	SLTM TPD52	2.45e-05	6	45	2	37140169
Pubmed	Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1.	PIP5K1A PIP5K1C	2.45e-05	6	45	2	14614850
Pubmed	Smurf1 regulates lung cancer cell growth and migration through interaction with and ubiquitination of PIPKIγ.	PIP5K1A PIP5K1C	2.45e-05	6	45	2	28581524
Pubmed	Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci.	KRT6A KRT6B	2.45e-05	6	45	2	25704602
Pubmed	Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development.	PIP5K1A PIP5K1C	3.42e-05	7	45	2	15018809
Pubmed	Deciphering TGF-β3 function in medial edge epithelium specification and fusion during mouse secondary palate development.	KRT6A KRT6B	3.42e-05	7	45	2	25104574
Pubmed	Frizzled6 deficiency disrupts the differentiation process of nail development.	KRT6A KRT6B	3.42e-05	7	45	2	23439395
Pubmed	Prediction of local recurrence, distant metastases, and death after breast-conserving therapy in early-stage invasive breast cancer using a five-biomarker panel.	KRT6A KRT6B	3.42e-05	7	45	2	19720911
Pubmed	Remodeling of the myocardium in early trabeculation and cardiac valve formation; a role for TGFβ2.	TGFB2 VCAN	3.42e-05	7	45	2	24623077
Pubmed	Genetic variation in the DNA repair genes is predictive of outcome in lung cancer.	BLM EXO1	3.42e-05	7	45	2	17855454
Pubmed	Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.	BLM EXO1	4.56e-05	8	45	2	23254285
Pubmed	Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.	PIP5K1A PIP5K1C	4.56e-05	8	45	2	20622009
Pubmed	Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure.	KRT6A KRT6B	4.56e-05	8	45	2	18485343
Pubmed	An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis.	KRT6A KRT6B	4.56e-05	8	45	2	15371305
Pubmed	Btk-dependent regulation of phosphoinositide synthesis.	PIP5K1A PIP5K1C	4.56e-05	8	45	2	15046600
Pubmed	Topical Aminosalicylic Acid Improves Keratinocyte Differentiation in an Inducible Mouse Model of Harlequin Ichthyosis.	KRT6A KRT6B	4.56e-05	8	45	2	33294854
Pubmed	RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.	KRT6A KRT6B KRT6C	5.64e-05	57	45	3	31862882
Pubmed	Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Iγ in vivo.	PIP5K1A PIP5K1C	5.86e-05	9	45	2	22976293
Pubmed	A mutant mouse with severe anemia and skin abnormalities controlled by a new allele of the flaky skin (fsn) locus.	KRT6A KRT6B	5.86e-05	9	45	2	16093647
Pubmed	Type II keratins precede type I keratins during early embryonic development.	KRT6A KRT6B	5.86e-05	9	45	2	16180309
Pubmed	Loss of the cytoskeletal protein Pdlim7 predisposes mice to heart defects and hemostatic dysfunction.	TGFB2 VCAN	5.86e-05	9	45	2	24278323
Pubmed	Periderm Fate during Palatogenesis: TGF-β and Periderm Dedifferentiation.	KRT6A KRT6B	5.86e-05	9	45	2	36751050
Pubmed	RIP4 regulates epidermal differentiation and cutaneous inflammation.	KRT6A KRT6B	5.86e-05	9	45	2	19626033
Pubmed	Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice.	BLM EXO1	5.86e-05	9	45	2	24705021
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FNBP4 AKAP6 STOX2 ARID1B KAT6B WDR37	5.93e-05	529	45	6	14621295
Pubmed	Expression of TGF-betas in the embryonic nervous system: analysis of interbalance between isoforms.	TGFB2 VCAN	7.32e-05	10	45	2	18498095
Pubmed	A balance between elongation and trimming regulates telomere stability in stem cells.	BLM EXO1	7.32e-05	10	45	2	27918544
Pubmed	New consensus nomenclature for mammalian keratins.	KRT6A KRT6B KRT6C	7.61e-05	63	45	3	16831889
Pubmed	Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor.	KRT6A KRT6B KRT6C CCDC136	8.03e-05	176	45	4	27229929
Pubmed	A unique form of collective epithelial migration is crucial for tissue fusion in the secondary palate and can overcome loss of epithelial apoptosis.	KRT6A KRT6B	8.94e-05	11	45	2	35593401
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FNBP4 BLM PIP5K1A RICTOR ABCB7 CRYBG3 STXBP3 PLCH1 TPD52	1.03e-04	1487	45	9	33957083
Pubmed	Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA.	KRT6A KRT6B	1.07e-04	12	45	2	14610062
Pubmed	Transforming growth factor Beta2 is required for valve remodeling during heart development.	TGFB2 VCAN	1.07e-04	12	45	2	21780244
Pubmed	An approach based on a genome-wide association study reveals candidate loci for narcolepsy.	AKAP6 WDR37 NFAT5 ADGRG6	1.15e-04	193	45	4	20677014
Pubmed	Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F.	KRT6A KRT6B KRT6C	1.28e-04	75	45	3	31527668
Interaction	PHTF1 interactions	PHTF2 KRT6A KRT6B KRT6C	1.02e-07	20	45	4	int:PHTF1
Interaction	RNF208 interactions	KRT6A KRT6B USP54 KRT6C	2.35e-05	75	45	4	int:RNF208
Interaction	CFAP184 interactions	RICTOR USP54 PLCH1 WDR37 CCDC136	2.97e-05	162	45	5	int:CFAP184
Interaction	KRT28 interactions	KRT6A KRT6B KRT6C	4.05e-05	30	45	3	int:KRT28
Interaction	KRT26 interactions	KRT6A KRT6B KRT6C	6.48e-05	35	45	3	int:KRT26
Interaction	KRT25 interactions	KRT6A KRT6B KRT6C	6.48e-05	35	45	3	int:KRT25
Interaction	PGBD5 interactions	PIP5K1A PIP5K1C	1.02e-04	7	45	2	int:PGBD5
Interaction	PIP5KL1 interactions	PIP5K1A PIP5K1C	1.02e-04	7	45	2	int:PIP5KL1
Cytoband	12q13.13	KRT6A KRT6B KRT6C	4.03e-05	67	45	3	12q13.13
Cytoband	10q22.2	USP54 KAT6B	7.52e-04	41	45	2	10q22.2
Cytoband	Ensembl 112 genes in cytogenetic band chr6q24	GRM1 ADGRG6	2.69e-03	78	45	2	chr6q24
Cytoband	Ensembl 112 genes in cytogenetic band chr5q14	MSH3 VCAN	7.93e-03	136	45	2	chr5q14
Cytoband	Ensembl 112 genes in cytogenetic band chr5p13	RICTOR CPLANE1	8.27e-03	139	45	2	chr5p13
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	KRT6A KRT6B KRT6C	8.28e-03	423	45	3	chr12q13
GeneFamily	Keratins, type II	KRT6A KRT6B KRT6C	1.17e-05	27	30	3	609
GeneFamily	AT-rich interaction domain containing	JARID2 ARID1B	2.76e-04	15	30	2	418
Coexpression	GU_PDEF_TARGETS_DN	TGFB2 KRT6A KRT6B KRT6C	6.62e-07	40	45	4	M10480
Coexpression	GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_UP	BLM EXO1 ABCB7 PLCH1 PIP5K1C ADGRG6	1.07e-06	197	45	6	M5150
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	BLM TGFB2 JARID2 PIP5K1A MSH3 CRYBG3 STXBP3 KAT6B WDR37 ADGRG6	1.48e-06	856	45	10	M4500
Coexpression	WHITFIELD_CELL_CYCLE_S	BLM EXO1 PHTF2 CPLANE1 ADGRG6	5.83e-06	150	45	5	M2075
Coexpression	ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	PHTF2 JARID2 KAT6B WDR37 F2RL1	2.29e-05	199	45	5	M1746
Coexpression	ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	PHTF2 JARID2 KAT6B WDR37 F2RL1	2.35e-05	200	45	5	MM1033
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder urothelium (LCM)_emap-30380_k-means-cluster#5_top-relative-expression-ranked_1000	PHTF2 F2RL1 PLS1 TPD52 ADGRG6	2.68e-05	167	45	5	gudmap_developingLowerUrinaryTract_P2_bladder urothelium (LCM)_1000_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#5_top-relative-expression-ranked_500	FNBP4 TGFB2 WDR37 MGA	4.11e-05	91	45	4	gudmap_developingGonad_e14.5_ epididymis_500_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000	TGFB2 KIAA1958 MSH3 CPLANE1 NFAT5 VCAN	4.82e-05	312	45	6	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	TGFB2 MSH3 ABCB7 CPLANE1 NFAT5 VCAN	6.58e-05	330	45	6	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#1_top-relative-expression-ranked_1000	FNBP4 TGFB2 WDR37 MGA	7.20e-05	105	45	4	gudmap_developingGonad_e18.5_epididymis_1000_k1
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_200	CPLANE1 NFAT5 VCAN	8.32e-05	40	45	3	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k4
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_1000	FNBP4 WDR37 MGA NFAT5	1.37e-04	124	45	4	gudmap_developingGonad_e16.5_epididymis_1000_k1
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500	BLM EXO1 PHTF2 FGD6 PLS1 ADGRG6	2.04e-04	406	45	6	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000	EXO1 PHTF2 KIAA1958 RICTOR MSH3 PLCH1 NFAT5 VCAN	2.05e-04	779	45	8	gudmap_developingKidney_e15.5_Cap mesenchyme_1000
CoexpressionAtlas	kidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_500	PLCH1 F2RL1 PLS1 VCAN TPD52 ADGRG6	2.21e-04	412	45	6	gudmap_kidney_e15.5_Podocyte_MafB_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	TGFB2 KIAA1958 KRT6A STOX2 MSH3 CPLANE1 NFAT5 VCAN	2.58e-04	806	45	8	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500_k-means-cluster#4	KRT6A KRT6B KRT6C	2.66e-04	59	45	3	Arv_EB-LF_500_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500	KIAA1958 CPLANE1 NFAT5 VCAN	2.77e-04	149	45	4	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	BLM EXO1 PHTF2 ABCB7 CPLANE1 MGA FGD6 PLS1	2.90e-04	820	45	8	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	BLM EXO1 PHTF2 JARID2 CPLANE1 FGD6 PLS1 ADGRG6	2.95e-04	822	45	8	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_1000	BLM MSH3 PLCH1 FGD6 VCAN	3.76e-04	293	45	5	gudmap_developingKidney_e15.5_Podocyte cells_1000_k4
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_500	EXO1 PLS1 ADGRG6	4.05e-04	68	45	3	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k1_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_500	TGFB2 MSH3 CPLANE1 VCAN	4.09e-04	165	45	4	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_500
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_500	EXO1 PLS1 ADGRG6	4.79e-04	72	45	3	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k3_500
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	SLTM EXO1 PHTF2 KIAA1958 JARID2 STOX2 ABCB7 PLCH1 CPLANE1 WDR37	4.82e-04	1370	45	10	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	facebase_RNAseq_e8.5_FloorPlate_2500_K3	SLTM EXO1 PHTF2 KIAA1958 JARID2 STOX2 MSH3 ABCB7 PLCH1 MGA	4.85e-04	1371	45	10	facebase_RNAseq_e8.5_FloorPlate_2500_K3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#1_top-relative-expression-ranked_1000	PLCH1 F2RL1 PLS1 ADGRG6	6.68e-04	188	45	4	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k1
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#1_top-relative-expression-ranked_1000	TGFB2 PIP5K1A KAT6B MGA	7.65e-04	195	45	4	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_500	TGFB2 NFAT5 VCAN	8.89e-04	89	45	3	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k2
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_500	FNBP4 WDR37 MGA	9.48e-04	91	45	3	gudmap_developingGonad_e16.5_epididymis_500_k4
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	BLM PHTF2 ABCB7 CPLANE1 PLS1	9.66e-04	361	45	5	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500	TGFB2 STOX2 CPLANE1 VCAN	9.91e-04	209	45	4	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000	TGFB2 MSH3 CPLANE1 VCAN	9.91e-04	209	45	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	TGFB2 KRT6A MSH3 KAT6B CPLANE1 NFAT5 VCAN	1.09e-03	769	45	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	EXO1 PHTF2 PIP5K1A RICTOR CPLANE1 MGA NFAT5	1.15e-03	776	45	7	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_SmallAirwayEpithel_top-relative-expression-ranked_100	KRT6A KRT6B KRT6C	1.18e-03	98	45	3	PCBC_ctl_SmallAirwayEpithel_100
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_BronchioEpithel_top-relative-expression-ranked_100	KRT6A KRT6B KRT6C	1.18e-03	98	45	3	PCBC_ctl_BronchioEpithel_100
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_100	STOX2 VCAN	1.18e-03	24	45	2	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_100
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000	BLM EXO1 PHTF2 JARID2 PLS1 TPD52 ADGRG6	1.19e-03	781	45	7	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	FNBP4 KIAA1958 MSH3 MGA NFAT5	1.20e-03	379	45	5	gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000	BLM CRYBG3 PLCH1 F2RL1 PLS1 VCAN TPD52	1.21e-03	783	45	7	gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	FNBP4 TGFB2 PIP5K1A CPLANE1 WDR37 MGA NFAT5	1.27e-03	790	45	7	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_100	PLCH1 VCAN	1.28e-03	25	45	2	gudmap_kidney_P4_CapMesRenVes_Crym_k3_100
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_1000	BLM EXO1 PHTF2 JARID2 PLS1 TPD52 ADGRG6	1.36e-03	799	45	7	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_1000
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500	MSH3 CPLANE1 NFAT5 F2RL1 ADGRG6	1.36e-03	390	45	5	gudmap_developingKidney_e15.5_cortic collect duct_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500	TGFB2 KRT6A KAT6B NFAT5 VCAN	1.36e-03	390	45	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000	PHTF2 KIAA1958 KRT6A PLCH1 F2RL1 PLS1 ADGRG6	1.37e-03	800	45	7	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	FNBP4 TGFB2 PIP5K1A CPLANE1 WDR37 MGA NFAT5	1.38e-03	801	45	7	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	EXO1 PIP5K1A RICTOR CPLANE1 WDR37 MGA NFAT5	1.41e-03	804	45	7	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	FNBP4 EXO1 PIP5K1A STOX2 CPLANE1 WDR37 MGA	1.43e-03	806	45	7	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#1_top-relative-expression-ranked_500	BLM EXO1 PLS1	1.43e-03	105	45	3	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k1_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	TGFB2 STOX2 MSH3 CPLANE1 VCAN	1.47e-03	397	45	5	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_100	NFAT5 ADGRG6	1.49e-03	27	45	2	gudmap_developingKidney_e15.5_cortic collect duct_100_k3
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_500	EXO1 KIAA1958 MSH3 PLCH1 VCAN	1.54e-03	401	45	5	gudmap_developingKidney_e15.5_Cap mesenchyme_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000	AKAP6 TGFB2 MSH3 ABCB7 CPLANE1 NFAT5 VCAN	1.55e-03	818	45	7	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	FNBP4 TGFB2 CPLANE1 WDR37 MGA	1.62e-03	406	45	5	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_500	MSH3 PLCH1 CPLANE1 F2RL1 ADGRG6	1.62e-03	406	45	5	gudmap_developingKidney_e15.5_ureter tip_500_flank cortic collct
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500	KIAA1958 KRT6A CPLANE1 NFAT5 VCAN	1.64e-03	407	45	5	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#1_top-relative-expression-ranked_1000	PHTF2 MSH3 PLCH1 VCAN	1.67e-03	241	45	4	gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k1
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	FNBP4 TGFB2 CPLANE1 WDR37 MGA	1.75e-03	413	45	5	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_1000	BLM MSH3 PLCH1 NFAT5 FGD6 VCAN TPD52	1.76e-03	836	45	7	gudmap_developingKidney_e15.5_Podocyte cells_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	TGFB2 PHTF2 KRT6A STXBP3 KAT6B WDR37 VCAN	1.76e-03	836	45	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	AKAP6 RICTOR USP54 KAT6B WDR37	9.58e-07	177	45	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	JARID2 RICTOR ARID1B NFAT5 VCAN	1.43e-06	192	45	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	JARID2 RICTOR ARID1B NFAT5 VCAN	1.47e-06	193	45	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FNBP4 FAM133B MGA NFAT5	1.72e-05	153	45	4	88ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FNBP4 FAM133B MGA NFAT5	1.72e-05	153	45	4	553dff9688a1996d8f4ba16e60c683593d781389
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG3 PLCH1 CPLANE1 VCAN	2.48e-05	168	45	4	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_TH\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 F2RL1 VCAN	2.91e-05	175	45	4	02c67a10cbe849fbf38f082f42517e42483e8cb7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TGFB2 STOX2 USP54 PLS1	3.18e-05	179	45	4	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 GRM1 ADGRG6	3.54e-05	184	45	4	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR1F PLCH1 FGD6 CCDC136	3.61e-05	185	45	4	5a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STOX2 PLCH1 PLS1 ADGRG6	3.69e-05	186	45	4	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	JARID2 PLCH1 FGD6 VCAN	3.77e-05	187	45	4	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KIAA1958 ABCB7 PIP5K1C VCAN	3.77e-05	187	45	4	1eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AKAP6 STOX2 CRYBG3 KAT6B	3.85e-05	188	45	4	e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	STOX2 PLCH1 PLS1 TPD52	3.93e-05	189	45	4	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 CCDC136 ADGRG6	4.26e-05	193	45	4	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 GRM1 ADGRG6	4.26e-05	193	45	4	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 CCDC136 ADGRG6	4.26e-05	193	45	4	3ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	MSH3 CRYBG3 CPLANE1 MGA	4.26e-05	193	45	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 CCDC136 ADGRG6	4.26e-05	193	45	4	2189da4b727e25e62669d7b9257f06493be21a27
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 GRM1 ADGRG6	4.26e-05	193	45	4	e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 CCDC136 ADGRG6	4.35e-05	194	45	4	83863da11dfbe59b2d0a2c08db40b537c150588c
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1958 STOX2 USP54 PLCH1	4.80e-05	199	45	4	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1958 STOX2 USP54 PLCH1	4.80e-05	199	45	4	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	(02)_MMP9/10+-(1)_GFP\|(02)_MMP9/10+ / shred by cell type by condition	JARID2 KRT6A KRT6B VCAN	4.80e-05	199	45	4	448ba982be804007f991d469eca9d885b21ae499
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1958 STOX2 USP54 PLCH1	4.80e-05	199	45	4	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	JARID2 STOX2 PLCH1 VCAN	4.80e-05	199	45	4	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	BLM PLCH1 CCDC136 ADGRG6	4.89e-05	200	45	4	347a510755374c6a66acee326565dfc447993f18
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	FNBP4 FAM133B RICTOR ARID1B	4.89e-05	200	45	4	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	droplet-Lung-1m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MSH3 VCAN TPD52	2.92e-04	128	45	3	376102331d79010c1b2ce26e6ab0134c7b8a4ec3
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_-_proliferative\|E16.5-samps / Age Group, Lineage, Cell class and subclass	KRT6A KRT6B USP54	3.49e-04	136	45	3	96370f0e3abf1c9ec7a91595b5d0f97ac2ab4b78
ToppCell	10x5'-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	AKAP6 TGFB2 ADGRG6	3.88e-04	141	45	3	7671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCell	Fetal_29-31_weeks-Immune-mast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EXO1 JARID2 HTR1F	4.21e-04	145	45	3	dc89d817a9bef24a07e992efdab4136f12ceb399
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EXO1 CRYBG3 ZNF77	4.38e-04	147	45	3	2d9044ddf01b6838a44a4518b442d7e7cb0bf910
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	JARID2 RICTOR VCAN	4.56e-04	149	45	3	768877bade04ca0321593b8470b5011ad8270431
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TGFB2 STYXL2 F2RL1	4.74e-04	151	45	3	8ffd71d847fe1aeebe7f43c4b6ca73efb19d6041
ToppCell	facs-Marrow-T-cells-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B VCAN	4.83e-04	152	45	3	d279592c501fca9cb474ad916fea32282e6969cb
ToppCell	facs-Marrow-T-cells-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B VCAN	4.83e-04	152	45	3	3b59143b2b4ee24eb6378f87ff568124193256e9
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	STYXL2 KRT6B PIP5K1C	4.93e-04	153	45	3	e0fbbfd4d13031412e0b985322c8b99c56eb7af5
ToppCell	18-Airway-Epithelial-Goblet-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	FSIP2 KIAA1958 F2RL1	4.93e-04	153	45	3	14a60220e169ce642771636de982a7b02e5b2608
ToppCell	facs-Trachea-24m-Hematologic-myeloid-granulocyte-granulocyte_l26\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BLM MSH3 ADGRG6	5.21e-04	156	45	3	da5cfa8fa9595613f04ce9511f8b42bad34d995a
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	KRT6A KRT6B FGD6	5.61e-04	160	45	3	830f17bad94de05612fe6d53d39e42a4b3f3e2f3
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	KRT6A KRT6B FGD6	5.61e-04	160	45	3	18ae6822915d16699beb9047baeef9b006901a35
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM133B RICTOR WDR37	5.61e-04	160	45	3	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C	6.03e-04	164	45	3	de1646dbcf2a10b48e021acf7dc63e803e6a47ce
ToppCell	droplet-Fat-Scat-18m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JARID2 VCAN TPD52	6.14e-04	165	45	3	015f8f408d7fd17292defe63fa02b16eed642dfb
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	ARID1B CPLANE1 MGA	6.25e-04	166	45	3	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AKAP6 F2RL1 PLS1	6.36e-04	167	45	3	8ec7a98b542b134f48df8fbec351693cc5cfe55c
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AKAP6 F2RL1 PLS1	6.36e-04	167	45	3	a9f28c4649ce344ae3ba3a3acb58da9c7efad901
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGFB2 PLCH1 ADGRG6	6.36e-04	167	45	3	17c653b46507c8bb85da95836ae72a6015336142
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT6A KRT6B F2RL1	6.47e-04	168	45	3	f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCell	Control\|World / group, cell type (main and fine annotations)	STOX2 USP54 PLCH1	6.47e-04	168	45	3	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BLM F2RL1 PLS1	6.47e-04	168	45	3	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 F2RL1 PLS1	6.58e-04	169	45	3	e348d9877a1bcad4f33dd7b2ce6cb0049583c4d2
ToppCell	3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	AKAP6 PLCH1 ADGRG6	6.58e-04	169	45	3	241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 F2RL1 PLS1	6.58e-04	169	45	3	3167ca0c826244280e0e07d1e02656cf5e4e75a5
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BLM EXO1 VCAN	6.58e-04	169	45	3	335619507857383c3b0b507cdf05d786ed59e585
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A KRT6B VCAN	6.69e-04	170	45	3	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6\|TCGA-Bladder / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C	6.81e-04	171	45	3	0e78389f8f3d54570a6deb3dd307b865b46307e9
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 RICTOR F2RL1	6.81e-04	171	45	3	6f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 RICTOR F2RL1	6.81e-04	171	45	3	ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	TGFB2 VCAN ADGRG6	6.92e-04	172	45	3	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 GRM1	6.92e-04	172	45	3	4f2303dee1f816093e580ea8a4a8d7e3e4f36368
ToppCell	droplet-Fat-Scat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JARID2 VCAN TPD52	6.92e-04	172	45	3	8a4a5ad65eec92ce4fa45c5aa01c28666307455b
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	TGFB2 FSIP2 ADGRG6	6.92e-04	172	45	3	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	TCGA-Head_and_Esophagus\|World / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C	6.92e-04	172	45	3	eb18aa179db1818f408c38e442ecfed8582d7dbc
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ANKRD34C GRM1 CCDC136	7.04e-04	173	45	3	7e3897868dd3f6e4974f593c60649a543ffc8693
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HTR1F PLCH1 F2RL1	7.04e-04	173	45	3	34357f0e22c4b6d84582492c82c1ea733ca8477d
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AKAP6 TGFB2 GRM1	7.04e-04	173	45	3	5c55e1e27e9e3e77600d378cc87b51cc73907527
ToppCell	severe_COVID-19-HSPC\|severe_COVID-19 / disease group, cell group and cell class (v2)	STOX2 HTR1F ADGRG6	7.16e-04	174	45	3	6d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KRT6A KRT6B KRT6C	7.16e-04	174	45	3	aceca0a22bb1e380835e792681cfc9b752fb5496
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KRT6A KRT6B USP54	7.40e-04	176	45	3	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	KRT6A F2RL1 MUCL3	7.52e-04	177	45	3	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	severe_COVID-19-HSPC\|World / disease group, cell group and cell class (v2)	STOX2 HTR1F ADGRG6	7.52e-04	177	45	3	289f6aed6f054b04b01659434d8c8b467d1bf5dd
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5\|TCGA-Lung / Sample_Type by Project: Shred V9	KRT6A KRT6B KRT6C	7.52e-04	177	45	3	a0c7d08469c513cecf87777c19876884f1511570
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIP5K1A HTR1F FGD6	7.52e-04	177	45	3	75cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	KRT6A F2RL1 MUCL3	7.52e-04	177	45	3	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFB2 F2RL1 ADGRG6	7.65e-04	178	45	3	445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCell	21-Trachea-Epithelial-Submucosal_gland\|Trachea / Age, Tissue, Lineage and Cell class	TGFB2 KRT6B TPD52	7.65e-04	178	45	3	3e406e38eea0d38dc25edecf703c4c89ec6a28e0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_TH\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLM PLCH1 VCAN	7.77e-04	179	45	3	797d165718dd1d819e65add3a7859f87b32238a5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	STOX2 USP54 TPD52	7.77e-04	179	45	3	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR1F PLCH1 CCDC136	7.90e-04	180	45	3	a407376209d80177bf7fc4200219030c83cb5f14
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TGFB2 F2RL1 TPD52	8.15e-04	182	45	3	204530444e35d4977a7239ac176f477e9e5c29ab
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGFB2 F2RL1 VCAN	8.15e-04	182	45	3	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ANKRD34C GRM1 CCDC136	8.15e-04	182	45	3	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B KRT6C	8.15e-04	182	45	3	007fa56ed8b91f9af0df2114c00410b2f6cec8b6
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	KIAA1958 ABCB7 PIP5K1C	8.28e-04	183	45	3	228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	KRT6A STOX2 ANKRD34C	8.28e-04	183	45	3	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM133B KRT6A F2RL1	8.28e-04	183	45	3	6e5b39c0170d62eb7fdd411dcfff51ed176573d0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLCH1 GRM1 CCDC136	8.28e-04	183	45	3	7961e05c6e9964da159059c6bfb4f7e7e14308c2
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epi_progenitor\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLCH1 F2RL1 TPD52	8.28e-04	183	45	3	031b4ffd95114dc10d2932c67d2cfef139b3fd2e
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TGFB2 VCAN ADGRG6	8.28e-04	183	45	3	f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCell	E12.5-Epithelial-airway_epithelial_cell-club_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLS1 TPD52 ADGRG6	8.42e-04	184	45	3	a69c3c57cd939b2888f548a0fbca3392ad310445
ToppCell	COVID-19-lung-Plasma_cells_PRDM1/BLIMP_int\|lung / Disease (COVID-19 only), tissue and cell type	BLM EXO1 TPD52	8.42e-04	184	45	3	480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLCH1 PLS1 TPD52	8.42e-04	184	45	3	886d2d9bf2fe31207f17e3edc309ef44029924e1
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	STOX2 PLCH1 MUCL3	8.42e-04	184	45	3	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	E12.5-Epithelial-airway_epithelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLS1 TPD52 ADGRG6	8.42e-04	184	45	3	3df78b17098b50e1a7f2c8791bf2d0806328330a
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLCH1 PLS1 TPD52	8.42e-04	184	45	3	936b39377eebea3961d702532779f6cd27953be7
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PLCH1 PLS1 TPD52	8.42e-04	184	45	3	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP54 PLCH1 TPD52	8.55e-04	185	45	3	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT6A KRT6B KRT6C	3.88e-04	50	31	3	GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPI3
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT6A KRT6B KRT6C	3.88e-04	50	31	3	GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPISEN
Drug	SC-791	KRT6A KRT6B KRT6C	1.44e-07	6	45	3	CID010291510
Drug	clobestasol propionate	KRT6A KRT6B KRT6C	4.81e-06	17	45	3	CID000002791
Drug	dithranol	KRT6A KRT6B KRT6C	5.77e-06	18	45	3	CID000002202
Drug	Olux	KRT6A KRT6B KRT6C	8.03e-06	20	45	3	CID000032797
Drug	N1-acetylspermidine	KRT6A KRT6B KRT6C	8.03e-06	20	45	3	CID000000496
Drug	MK-6	KRT6A KRT6B KRT6C	1.42e-05	24	45	3	CID005283547
Drug	Bhg-(2-1)fuc	KRT6A KRT6B KRT6C	1.61e-05	25	45	3	CID005287784
Drug	betamethasone valerate	KRT6A KRT6B KRT6C	2.28e-05	28	45	3	CID000016533
Drug	2-Formyl-Protoporphryn Ix	KRT6A KRT6B KRT6C	3.12e-05	31	45	3	CID011963946
Drug	AGN 193109	KRT6A KRT6B KRT6C	3.12e-05	31	45	3	CID000177238
Drug	4,4'-thiodiphenol	KRT6A KRT6B KRT6C	3.44e-05	32	45	3	CID000017570
Drug	Omeprazole [73590-58-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A	TGFB2 PHTF2 PLCH1 NFAT5 TPD52	3.86e-05	193	45	5	2828_DN
Drug	chrysarobin	KRT6A KRT6B KRT6C	5.35e-05	37	45	3	CID000068111
Drug	tsuwabukinonol	KRT6A KRT6B KRT6C	5.35e-05	37	45	3	CID006440419
Drug	CaLam	KRT6A KRT6B KRT6C	6.27e-05	39	45	3	CID004126474
Disease	Pachyonychia congenita syndrome	KRT6A KRT6B	1.24e-05	4	43	2	cv:C0265334
Disease	Pachyonychia Congenita, Type 2 (disorder)	KRT6A KRT6B	1.24e-05	4	43	2	C1721007
Disease	Pachyonychia Congenita, Jadassohn Lewandowsky Type	KRT6A KRT6B	1.24e-05	4	43	2	C1706595
Disease	pachyonychia congenita (is_implicated_in)	KRT6A KRT6B	1.24e-05	4	43	2	DOID:0050449 (is_implicated_in)
Disease	Pachyonychia Congenita	KRT6A KRT6B	2.07e-05	5	43	2	C0265334
Disease	Urogenital Abnormalities	TGFB2 WDR37	4.34e-05	7	43	2	C0042063
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	EXO1 MSH3	3.49e-04	19	43	2	C2936783
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	EXO1 MSH3	3.49e-04	19	43	2	C1333991
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	EXO1 MSH3	6.59e-04	26	43	2	C0009405
Disease	Hereditary non-polyposis colorectal cancer syndrome	EXO1 MSH3	7.11e-04	27	43	2	C1112155
Disease	Hereditary Nonpolyposis Colorectal Cancer	EXO1 MSH3	8.21e-04	29	43	2	C1333990
Disease	differentiated thyroid carcinoma	STOX2 ADGRG6	1.20e-03	35	43	2	EFO_1002017
Disease	body weight	AKAP6 TGFB2 HTR1F ITIH6 KAT6B MGA ADGRG6	2.14e-03	1261	43	7	EFO_0004338

Protein segments in the cluster

Peptide	Gene	Start	Entry
TTSFKGTSPSSKYVK	KCTD10	21	Q9H3F6
IITTDKSSSGTKTTK	ANKRD34C	151	P0C6C1
KSSSGTKTTKQYLNV	ANKRD34C	156	P0C6C1
KTTDYSVLTTKKTYS	VCAN	2151	P13611
KKAYDLSSSTSDTKI	CRYBG3	96	Q68DQ2
LESGEKSTKSVSTSY	HTR1F	231	P30939
KSTKSVSTSYVLEKS	HTR1F	236	P30939
IGSNSTYLTSKSKSS	ADGRG6	1166	Q86SQ4
ESKSKKSSSSTTTGE	ARID1B	1111	Q8NFD5
KSSSSTTTGEKITKV	ARID1B	1116	Q8NFD5
TSTYISASTLKVNKK	KAT6B	416	Q8WYB5
TASKSANKRSKSIYT	MSH3	216	P20585
SSTIKYTTTSSSSRK	KRT6C	546	P48668
SFASKTGSETKITYS	MGA	1911	Q8IWI9
SSTIKYTTTSSSSRK	KRT6A	546	P02538
FSKIFSTISSTKTKE	FSIP2	6021	Q5CZC0
KTSISSFKDKSISTS	PLS1	536	Q14651
SSTIKYTTTSSSSRK	KRT6B	546	P04259
KRSSTIFKTTKSVGS	NFAT5	616	O94916
STVVSTKTIKTSHYL	RICTOR	1256	Q6R327
SSGETTYKKTTSSAL	PIP5K1A	71	Q99755
RKSSSYSSSSTTVKT	F2RL1	381	P55085
KISSKTKSSSIIGSS	BLM	1366	P54132
KEKKKSGRYSSSSSS	FAM133B	96	Q5BKY9
ISSAQISTYKEKSSS	CPLANE1	1991	Q9H799
PKFYLSSTTTASTKK	ITIH6	666	Q6UXX5
GKSLTFSDTSTKTLY	GRM1	941	Q13255
STTGKSTVTRKSDKT	MUCL3	171	Q3MIW9
SPSKTVKYTATVTKG	JARID2	331	Q92833
TLGSETSKKYSNTSI	PHTF2	686	Q8N3S3
DIYSKEKTISVSSSK	FNBP4	276	Q8N3X1
SGETTYKKTTSSTLK	PIP5K1C	66	O60331
SKTSSKDDKGSTSST	SLTM	361	Q9NWH9
ISSTKKATEGKTSLS	STXBP3	311	O00186
LYKSSSADSLSTTKI	EXO1	741	Q9UQ84
KTYETASLKSTSTLA	ABCB7	361	O75027
TKSLSKDSSFSSTKS	AKAP6	1321	Q13023
TTSNSSITYKKSYGS	CCDC136	806	Q96JN2
SITYKKSYGSTSSSD	CCDC136	811	Q96JN2
TSTYTSGDQKTIKST	TGFB2	256	P61812
RTASVTYVKSLSSKK	ZNF77	196	Q15935
KSTVNFSYKTETLSK	STOX2	241	Q9P2F5
TESKSSSYKFSKSQS	STYXL2	971	Q5VZP5
KSSYPSSEEKSSEKS	FGD6	521	Q6ZV73
KKTTKSRSKSYSTDD	PLCH1	556	Q4KWH8
YKASTSKIVSSFKTT	WDR37	126	Q9Y2I8
TATSAYKKTSETLSQ	TPD52	131	P55327
SSESKSSSSSKYRPT	USP54	561	Q70EL1
FSITSSTFSSSTKKL	KIAA1958	496	Q8N8K9