Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetallopeptidase activity

BMP1 MMP24 TLL1 XPNPEP2 PRPF8 MMP16

1.99e-04200846GO:0008237
GeneOntologyMolecularFunctionpeptidase activity

MST1 BMP1 MMP24 SENP1 OTULIN TLL1 MST1L XPNPEP2 PRPF8 MMP16

4.13e-046548410GO:0008233
GeneOntologyMolecularFunctionU1 snRNA binding

GEMIN5 PRPF8

4.82e-048842GO:0030619
GeneOntologyMolecularFunctionarmadillo repeat domain binding

LEF1 AXIN1

6.18e-049842GO:0070016
DomainZnMc

BMP1 MMP24 TLL1 MMP16

8.70e-0629854SM00235
DomainPeptidase_Metallo

BMP1 MMP24 TLL1 MMP16

8.70e-0629854IPR006026
DomainFN3

MYOM3 ROBO2 IGSF9B FLRT3 USH2A HCFC1 IGDCC4

2.15e-05185857SM00060
DomainFN3

MYOM3 ROBO2 IGSF9B FLRT3 USH2A HCFC1 IGDCC4

3.43e-05199857PS50853
DomainFN3_dom

MYOM3 ROBO2 IGSF9B FLRT3 USH2A HCFC1 IGDCC4

4.69e-05209857IPR003961
Domain-

CLGN CANX

6.12e-0538522.10.250.10
DomainCALRETICULIN_REPEAT

CLGN CANX

6.12e-053852PS00805
DomainBMP_1/tolloid-like

BMP1 TLL1

6.12e-053852IPR015446
DomainIg-like_fold

LILRB3 LILRA3 HMCN2 RBPJL MYOM3 LILRA6 ROBO2 IGSF9B FLRT3 USH2A HCFC1 IGDCC4

8.13e-057068512IPR013783
Domainfn3

MYOM3 ROBO2 IGSF9B FLRT3 USH2A IGDCC4

9.64e-05162856PF00041
DomainCalret/calnex

CLGN CANX

1.22e-044852IPR001580
DomainDUF3377

MMP24 MMP16

1.22e-044852PF11857
DomainCALRETICULIN_1

CLGN CANX

1.22e-044852PS00803
DomainCALRETICULIN_2

CLGN CANX

1.22e-044852PS00804
DomainCalret/calnex_CS

CLGN CANX

1.22e-044852IPR018124
DomainPept_M10A_metallopeptidase_C

MMP24 MMP16

1.22e-044852IPR021805
DomainCalreticulin

CLGN CANX

1.22e-044852PF00262
Domain-

RGS6 RGS11 AXIN1

1.32e-04228531.10.196.10
DomainRGS_subdom1

RGS6 RGS11 AXIN1

1.32e-0422853IPR024066
DomainPAN_AP

MST1 MST1L

2.03e-045852SM00473
DomainCalreticulin/calnexin_P_dom

CLGN CANX

2.03e-045852IPR009033
DomainPeptidase_M12A

BMP1 TLL1

3.03e-046852IPR001506
DomainAstacin

BMP1 TLL1

3.03e-046852PF01400
DomainA1B_glyco/leuk_Ig-like_rcpt

LILRA3 LILRA6

3.03e-046852IPR016332
DomainPAN

MST1 MST1L

4.24e-047852PS50948
DomainPan_app

MST1 MST1L

4.24e-047852IPR003609
DomainPAN_1

MST1 MST1L

4.24e-047852PF00024
DomainMetalloPept_cat_dom

BMP1 MMP24 TLL1 MMP16

5.09e-0481854IPR024079
Domain-

BMP1 MMP24 TLL1 MMP16

5.09e-04818543.40.390.10
DomainRGS

RGS6 RGS11 AXIN1

5.36e-0435853PF00615
DomainRGS

RGS6 RGS11 AXIN1

5.36e-0435853SM00315
DomainFHA_dom

FHAD1 PNKP AFDN

5.83e-0436853IPR000253
DomainRGS

RGS6 RGS11 AXIN1

5.83e-0436853PS50132
Domain-

FHAD1 PNKP AFDN

5.83e-04368532.60.200.20
DomainIG

LILRB3 LILRA3 HMCN2 MYOM3 LILRA6 ROBO2 IGSF9B IGDCC4

6.60e-04421858SM00409
DomainIg_sub

LILRB3 LILRA3 HMCN2 MYOM3 LILRA6 ROBO2 IGSF9B IGDCC4

6.60e-04421858IPR003599
DomainIGc2

LILRA3 HMCN2 MYOM3 ROBO2 IGSF9B IGDCC4

7.11e-04235856SM00408
DomainIg_sub2

LILRA3 HMCN2 MYOM3 ROBO2 IGSF9B IGDCC4

7.11e-04235856IPR003598
DomainPI3Ka

PIK3CB PI4KA

7.22e-049852PF00613
Domain-

PIK3CB PI4KA

7.22e-0498521.25.40.70
DomainPI3Ka

PIK3CB PI4KA

7.22e-049852SM00145
DomainRGS

RGS6 RGS11 AXIN1

7.39e-0439853IPR016137
DomainPIK_HELICAL

PIK3CB PI4KA

9.00e-0410852PS51545
DomainPI_Kinase

PIK3CB PI4KA

9.00e-0410852IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3CB PI4KA

9.00e-0410852IPR001263
Domain-

FAT2 CLGN CANX USH2A

9.28e-04958542.60.120.200
DomainZINC_PROTEASE

BMP1 MMP24 TLL1 MMP16

1.04e-0398854PS00142
DomainSMAD_FHA_domain

FHAD1 PNKP AFDN

1.71e-0352853IPR008984
DomainIg_I-set

HMCN2 MYOM3 ROBO2 IGSF9B IGDCC4

1.76e-03190855IPR013098
DomainI-set

HMCN2 MYOM3 ROBO2 IGSF9B IGDCC4

1.76e-03190855PF07679
DomainIG_LIKE

LILRB3 LILRA3 HMCN2 MYOM3 LILRA6 ROBO2 IGSF9B IGDCC4

1.76e-03491858PS50835
DomainIg-like_dom

LILRB3 LILRA3 HMCN2 MYOM3 LILRA6 ROBO2 IGSF9B IGDCC4

2.05e-03503858IPR007110
DomainPI3/4_kinase_CS

PIK3CB PI4KA

2.07e-0315852IPR018936
DomainEGF_CA

BMP1 FAT2 HMCN2 TLL1

2.33e-03122854SM00179
DomainGGL

RGS6 RGS11

2.36e-0316852SM00224
DomainG-gamma

RGS6 RGS11

2.36e-0316852PF00631
Domain-

RGS6 RGS11

2.36e-03168524.10.260.10
DomainGprotein-gamma

RGS6 RGS11

2.36e-0316852IPR001770
Domain-

PIK3CB PI4KA

2.36e-03168521.10.1070.11
DomainG_PROTEIN_GAMMA

RGS6 RGS11

2.36e-0316852PS50058
DomainPI3Kc

PIK3CB PI4KA

2.36e-0316852SM00146
DomainG-protein_gamma-like_dom

RGS6 RGS11

2.36e-0316852IPR015898
DomainEGF-like_Ca-bd_dom

BMP1 FAT2 HMCN2 TLL1

2.48e-03124854IPR001881
DomainKringle

MST1 MST1L

2.66e-0317852IPR000001
DomainKringle_CS

MST1 MST1L

2.66e-0317852IPR018056
DomainHemopexin_CS

MMP24 MMP16

2.66e-0317852IPR018486
DomainKRINGLE_2

MST1 MST1L

2.66e-0317852PS50070
DomainKringle

MST1 MST1L

2.66e-0317852PF00051
DomainKRINGLE_1

MST1 MST1L

2.66e-0317852PS00021
DomainKR

MST1 MST1L

2.66e-0317852SM00130
DomainPI3/4_kinase_cat_dom

PIK3CB PI4KA

2.99e-0318852IPR000403
DomainPI3_PI4_kinase

PIK3CB PI4KA

2.99e-0318852PF00454
DomainPI3_4_KINASE_3

PIK3CB PI4KA

2.99e-0318852PS50290
DomainPept_M10A_stromelysin-type

MMP24 MMP16

2.99e-0318852IPR016293
DomainPI3_4_KINASE_1

PIK3CB PI4KA

2.99e-0318852PS00915
DomainPI3_4_KINASE_2

PIK3CB PI4KA

2.99e-0318852PS00916
Domain-

LILRA3 RBPJL MYOM3 ROBO2 IGSF9B FLRT3 USH2A HCFC1 IGDCC4

3.16e-036638592.60.40.10
DomainPG_binding_1

MMP24 MMP16

3.69e-0320852PF01471
DomainPeptidoglycan-bd-like

MMP24 MMP16

3.69e-0320852IPR002477
DomainDEP

RGS6 RGS11

4.46e-0322852PF00610
DomainDEP

RGS6 RGS11

4.46e-0322852PS50186
DomainDEP

RGS6 RGS11

4.46e-0322852SM00049
Pubmed

GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes.

RGS6 GPR158 RGS11

1.51e-07587322689652
Pubmed

Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans.

LILRB3 LILRA6

6.19e-06287236449053
Pubmed

Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1.

BMP1 TLL1

6.19e-0628728661043
Pubmed

Platelet activating factor-acetylhydrolase (PAF-AH) activity and HDL levels, but not PAF-AH gene polymorphisms, are associated with successful aging in Sicilian octogenarians.

PLA2G7 PAFAH1B1

6.19e-06287218431085
Pubmed

Deletion of Axin1 in condylar chondrocytes leads to osteoarthritis-like phenotype in temporomandibular joint via activation of β-catenin and FGF signaling.

ACAN AXIN1

6.19e-06287230070692
Pubmed

Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway.

MST1 MST1L

6.19e-06287229760744
Pubmed

Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice.

BMP1 TLL1

6.19e-06287228000152
Pubmed

Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.

MST1 MST1L

6.19e-0628728393443
Pubmed

Molecular cloning and sequencing of calnexin-t. An abundant male germ cell-specific calcium-binding protein of the endoplasmic reticulum.

CLGN CANX

6.19e-0628728188695
Pubmed

MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis.

MST1 MST1L

6.19e-06287227609031
Pubmed

Dual roles of endogenous platelet-activating factor acetylhydrolase in a murine model of necrotizing enterocolitis.

PLA2G7 PAFAH1B1

6.19e-06287220531249
Pubmed

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model.

MST1 MST1L

6.19e-06287224980820
Pubmed

[Analysis of 994(G--> T) mutation in the plasma platelet-activating factor acetylhydrolase gene in the patients with cerebral infarction].

PLA2G7 PAFAH1B1

6.19e-06287216086290
Pubmed

Mst1 deletion reduces hyperglycemia-mediated vascular dysfunction via attenuating mitochondrial fission and modulating the JNK signaling pathway.

MST1 MST1L

6.19e-06287231206688
Pubmed

Skeletal muscle expression of bone morphogenetic protein-1 and tolloid-like-1 extracellular proteases in different fiber types and in response to unloading, food deprivation and differentiation.

BMP1 TLL1

6.19e-06287220658214
Pubmed

Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis.

BMP1 TLL1

6.19e-06287233169406
Pubmed

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients.

LILRB3 LILRA6

6.19e-06287219617579
Pubmed

Platelet-activating factor acetylhydrolase gene polymorphism and its activity in Japanese patients with multiple sclerosis.

PLA2G7 PAFAH1B1

6.19e-06287215081260
Pubmed

Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein.

MST1 MST1L

6.19e-06287210728827
Pubmed

Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism.

MST1 MST1L

6.19e-06287216961763
Pubmed

Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population.

LILRB3 LILRA6

6.19e-06287233526815
Pubmed

Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice.

MST1 MST1L

6.19e-06287239253972
Pubmed

Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues.

BMP1 TLL1

6.19e-0628727798260
Pubmed

Cerebral ischemia-reperfusion is modulated by macrophage-stimulating 1 through the MAPK-ERK signaling pathway.

MST1 MST1L

6.19e-06287232017081
Pubmed

H-2f, a tenth allele at the histocompatibility-2 locus in the mouse as determined by tumor transplantation.

PIK3CB AXIN1

6.19e-06287214379171
Pubmed

Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy.

MST1 MST1L

6.19e-06287230708325
Pubmed

Functional consequences of the macrophage stimulating protein 689C inflammatory bowel disease risk allele.

MST1 MST1L

6.19e-06287224409221
Pubmed

Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1.

MST1 MST1L

6.19e-06287227696525
Pubmed

Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification.

PLA2G7 PAFAH1B1

6.19e-06287217903175
Pubmed

SENP1 deficiency promotes ER stress-induced apoptosis by increasing XBP1 SUMOylation.

SENP1 XBP1

6.19e-06287222370484
Pubmed

Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein.

MST1 MST1L

6.19e-0628728340069
Pubmed

Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice.

MST1 MST1L

6.19e-0628729486989
Pubmed

Immunoglobulin-like receptors and the generation of innate immune memory.

LILRA3 LILRA6

6.19e-06287235034136
Pubmed

Treatment with XMU-MP-1 erases hyperglycaemic memory in hearts of diabetic mice.

MST1 MST1L

6.19e-06287233887258
Pubmed

HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.

MST1 MST1L

6.19e-06287225938541
Pubmed

Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair.

LILRB3 LILRA6

6.19e-06287224096970
Pubmed

Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.

ASXL1 CANX PRPF8 HCFC1 HSPB1

9.07e-0611187532683582
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

GCLC PI4KA CANX PAFAH1B1 AFDN CTH PLS1

1.17e-0530487732235678
Pubmed

Development of a deer mouse whole-genome radiation hybrid panel and comparative mapping of Mus chromosome 11 loci.

IGFBP1 CANX XBP1

1.20e-051887316416089
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MST1 URB1 PI4KA CANX MYOM3 DNAH2 LARP1 IGSF9B PRPF8 PLS1

1.56e-05736871029676528
Pubmed

Essential Roles of Bone Morphogenetic Protein-1 and Mammalian Tolloid-like 1 in Postnatal Root Dentin Formation.

BMP1 TLL1

1.85e-05387227847137
Pubmed

The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.

MST1 MST1L

1.85e-05387210225971
Pubmed

Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.

MST1 MST1L

1.85e-05387238430683
Pubmed

Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons.

MST1 MST1L

1.85e-05387212538524
Pubmed

Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes.

MST1 MST1L

1.85e-05387219339990
Pubmed

TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1.

MST1 MST1L

1.85e-05387226698664
Pubmed

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.

ASXL1 HCFC1

1.85e-05387221642991
Pubmed

Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction.

BMP1 TLL1

1.85e-05387219079247
Pubmed

Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition.

MST1 MST1L

1.85e-05387230063115
Pubmed

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.

BMP1 TLL1

1.85e-05387218824173
Pubmed

Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injury.

MST1 MST1L

1.85e-05387227218122
Pubmed

Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction.

MST1 MST1L

1.85e-05387217395874
Pubmed

Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases.

BMP1 TLL1

1.85e-05387212808086
Pubmed

BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis.

BMP1 TLL1

1.85e-05387228068493
Pubmed

Genetic deletion of Mst1 alters T cell function and protects against autoimmunity.

MST1 MST1L

1.85e-05387224852423
Pubmed

Next-generation sequencing to solve complex inherited retinal dystrophy: A case series of multiple genes contributing to disease in extended families.

PRPF8 USH2A

1.85e-05387228761320
Pubmed

Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme.

PLA2G7 PAFAH1B1

1.85e-05387211294621
Pubmed

Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases.

BMP1 TLL1

1.85e-05387232209430
Pubmed

Mst1 participates in the atherosclerosis progression through macrophage autophagy inhibition and macrophage apoptosis enhancement.

MST1 MST1L

1.85e-05387227496379
Pubmed

Macrophage-stimulating protein cooperates with erythropoietin to induce colony formation and MAP kinase activation in primary erythroid progenitor cells.

MST1 MST1L

1.85e-05387212804176
Pubmed

Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function.

MST1 MST1L

1.85e-05387212606483
Pubmed

Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice.

MST1 MST1L

1.85e-05387236623453
Pubmed

Bone morphogenetic protein-1 processes probiglycan.

BMP1 TLL1

1.85e-05387210896944
Pubmed

Hippo Kinase MST1-Mediated Cell Metabolism Reprograms the Homeostasis and Differentiation of Granulocyte Progenitor Cells.

MST1 MST1L

1.85e-05387237184367
Pubmed

CircRbms1 fosters MST1 mRNA and protein levels to motivate myocardial ischaemia-reperfusion injury via autophagic status.

MST1 MST1L

1.85e-05387238288506
Pubmed

The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues.

MST1 MST1L

1.85e-0538728545120
Pubmed

Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase.

BMP1 TLL1

1.85e-05387220043912
Pubmed

Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis.

MST1 MST1L

1.85e-05387225049204
Pubmed

Characterization of the mouse cDNA and gene coding for a hepatocyte growth factor-like protein: expression during development.

MST1 MST1L

1.85e-0538721832957
Pubmed

Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains.

BMP1 TLL1

1.85e-05387216507574
Pubmed

Activation of pro-survival CaMK4β/CREB and pro-death MST1 signaling at early and late times during a mouse model of prion disease.

MST1 MST1L

1.85e-05387225183307
Pubmed

MST1 mediates neuronal loss and cognitive deficits: A novel therapeutic target for Alzheimer's disease.

MST1 MST1L

1.85e-05387235525373
Pubmed

MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice.

MST1 MST1L

1.85e-05387227510910
Pubmed

Combination of melatonin and irisin ameliorates lipopolysaccharide-induced cardiac dysfunction through suppressing the Mst1-JNK pathways.

MST1 MST1L

1.85e-05387231976559
Pubmed

Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.

BMP1 TLL1

1.85e-05387224419319
Pubmed

Over-expressed MST1 impaired spatial memory via disturbing neural oscillation patterns in mice.

MST1 MST1L

1.85e-05387232468668
Pubmed

Nicorandil alleviates myocardial injury and post-infarction cardiac remodeling by inhibiting Mst1.

MST1 MST1L

1.85e-05387229127009
Pubmed

Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.

MST1 MST1L

1.85e-05387227465533
Pubmed

Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor.

LILRB3 LILRA3

1.85e-0538729278324
Pubmed

Suramin protects hepatocytes from LPS-induced apoptosis by regulating mitochondrial stress and inactivating the JNK-Mst1 signaling pathway.

MST1 MST1L

1.85e-05387230771091
Pubmed

Endoplasmic reticulum stress in the absence of calnexin.

CANX XBP1

1.85e-05387218528784
Pubmed

Hydrogen sulfide improves ox‑LDL‑induced expression levels of Lp‑PLA2 in THP‑1 monocytes via the p38MAPK pathway.

PLA2G7 CTH

1.85e-05387233760156
Pubmed

MST1 mediates the N-methyl-D-aspartate-induced excitotoxicity in mouse cortical neurons.

MST1 MST1L

1.85e-05387234967918
Pubmed

Hippo kinases Mst1 and Mst2 maintain NK cell homeostasis by orchestrating metabolic state and transcriptional activity.

MST1 MST1L

1.85e-05387238898027
Pubmed

WASP and Mst1 coregulate B-cell development and B-cell receptor signaling.

MST1 MST1L

1.85e-05387232045478
Pubmed

Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2.

MST1 MST1L

1.85e-05387227940445
Pubmed

Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis.

ACAN CANX XBP1

2.25e-052287325147951
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

PNKP TSR1 CANX GEMIN5 PRPF8 HCFC1 HSPB1

2.40e-0534087724332808
Pubmed

Inhibition of TLR4-induced IκB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein.

MST1 MST1L

3.70e-05487221078906
Pubmed

MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis.

MST1 MST1L

3.70e-05487236618429
Pubmed

Hyperglycemia-Induced Overexpression of PH Domain Leucine-Rich Repeat Protein Phosphatase 1 (PHLPP1) Compromises the Cardioprotective Effect of Ischemic Postconditioning Via Modulation of the Akt/Mst1 Pathway Signaling.

MST1 MST1L

3.70e-05487235715527
Pubmed

Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice.

RGS6 RGS11

3.70e-05487222371490
Pubmed

Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.

MST1 MST1L

3.70e-05487225074980
Pubmed

OSM mitigates post-infarction cardiac remodeling and dysfunction by up-regulating autophagy through Mst1 suppression.

MST1 MST1L

3.70e-05487227825852
Pubmed

MST1 deficiency promotes B cell responses by CD4+ T cell-derived IL-4, resulting in hypergammaglobulinemia.

MST1 MST1L

3.70e-05487228527887
Pubmed

Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration.

MST1 MST1L

3.70e-05487225133611
Pubmed

LncRNA SNHG17 knockdown promotes Parkin-dependent mitophagy and reduces apoptosis of podocytes through Mst1.

MST1 MST1L

3.70e-05487232627655
Pubmed

Macrophage MST1/2 Disruption Impairs Post-Infarction Cardiac Repair via LTB4.

MST1 MST1L

3.70e-05487234515499
Pubmed

Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein.

PLA2G7 PAFAH1B1

3.70e-05487218434304
Pubmed

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes.

MST1 MST1L

3.70e-05487222412158
InteractionLILRA6 interactions

LILRB3 LILRA3 LILRA6

2.99e-074863int:LILRA6
InteractionMMP20 interactions

MMP24 ACAN MMP16

8.81e-0610863int:MMP20
Cytoband5q33.2

LARP1 GEMIN5

4.19e-04168725q33.2
Cytoband19q13.4

LILRB3 LILRA3 LILRA6

4.68e-047987319q13.4
Cytoband17p13.3

TSR1 PAFAH1B1 PRPF8

6.42e-048887317p13.3
CytobandEnsembl 112 genes in cytogenetic band chr5q33

FAT2 LARP1 GEMIN5

1.50e-03118873chr5q33
CytobandEnsembl 112 genes in cytogenetic band chr4q31

CLGN TMEM131L SETD7

3.81e-03164873chr4q31
GeneFamilyFibronectin type III domain containing

MYOM3 ROBO2 IGSF9B FLRT3 USH2A IGDCC4

9.85e-06160566555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HMCN2 MYOM3 ROBO2 IGSF9B IGDCC4

1.39e-04161565593
GeneFamilyBone morphogenetic proteins|Astacins

BMP1 TLL1

1.40e-046562894
GeneFamilyCD molecules|Activating leukocyte immunoglobulin like receptors

LILRA3 LILRA6

1.40e-0465621181
GeneFamilyRegulators of G-protein signaling

RGS6 RGS11

1.91e-0321562720
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

RPGRIP1L SACS HCFC1 AXIN1

2.38e-03181564694
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP24 MMP16

2.49e-0324562891
GeneFamilyImmunoglobulin like domain containing

HMCN2 MYOM3 IGSF9B IGDCC4

3.00e-03193564594
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

RGS6 SELENOM TMEM131L IGSF9B HSPB1 CAP2

1.87e-061888769ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 RGS6 SPEF2 ROBO2 CTH MMP16

1.99e-06190876106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 RGS6 SPEF2 ROBO2 AFDN MMP16

2.25e-061948760b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 RPGRIP1L PLIN5 SPEF2 DNAH2 CES4A

2.25e-061948764a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BMP1 ACAN SELENOM ROBO2 MMP16 IGDCC4

2.60e-06199876d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BMP1 ACAN SELENOM ROBO2 MMP16 IGDCC4

2.60e-06199876bf138cc692df727e087d140c014149ee5da00d9d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WDR93 FHAD1 SPEF2 DNAH2 CES4A

2.03e-0516987514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellMonocytes-IFN-activated_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PLA2G7 FHAD1 LILRB3 LILRA3 LILRA6

2.15e-05171875df1b631618839bee4a18a2ba9c730321e5015f36
ToppCellfacs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A4GALT SELENOM XBP1 CCDC120 PLS1

2.21e-05172875a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A4GALT SELENOM XBP1 CCDC120 PLS1

2.21e-0517287565b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCellfacs-Marrow-T_cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLGN A4GALT SELENOM XBP1 PLS1

2.27e-05173875e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCellfacs-Marrow-T_cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLGN A4GALT SELENOM XBP1 PLS1

2.34e-051748753b1ee39e85e5f0d6b17fb3051dbfae66cb2be6ee
ToppCellfacs-Marrow-T_cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLGN A4GALT SELENOM XBP1 PLS1

2.40e-051758754be01bf30331162f1998216fb2871a4e626dc440
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RGS6 ACAN TMEM131L IGSF9B CAP2

2.40e-05175875d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RGS6 ACAN TMEM131L IGSF9B CAP2

2.40e-05175875454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIK3CB APBA1 GATAD1 TMEM131L PLS1

2.60e-0517887563f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIK3CB APBA1 GATAD1 TMEM131L PLS1

2.60e-0517887582c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIK3CB APBA1 GATAD1 TMEM131L PLS1

2.60e-05178875cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BMP1 SELENOM ROBO2 MMP16 IGDCC4

2.90e-05182875ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

WDR93 FHAD1 RPGRIP1L SPEF2 CHST9

2.90e-05182875e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

WDR93 FHAD1 SPEF2 DNAH2 CHST9

3.47e-05189875a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGS6 ACAN TMEM131L ROBO2 IGSF9B

3.47e-05189875127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGS6 ACAN TMEM131L ROBO2 IGSF9B

3.47e-051898752cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RGS6 A4GALT GATAD1 XPNPEP2 HSPB1

3.65e-0519187540e617d3c93f03ae87baf6c0b2304b617f5fe782
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 RGS6 AFDN CTH MMP16

3.74e-0519287504f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 RGS6 AFDN CTH MMP16

3.74e-05192875c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellIPF-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

RGS6 ACAN SELENOM TMEM131L CAP2

3.74e-051928759b06c7336624ef21f8e5393725b56038a8028e57
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 TLL1 SPEF2 FAM181B MMP16

3.74e-0519287581baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 RGS6 AFDN CTH MMP16

3.83e-0519387502f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 RGS6 SPEF2 AFDN MMP16

3.83e-051938756e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FHAD1 SPEF2 DNAH2 CES4A CHST9

3.83e-05193875ea345d34440b25f65358a53dc72831998d1c3620
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 RGS6 AFDN CTH MMP16

3.83e-051938755122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellBronchial-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MST1 RGS6 TLL1 A4GALT IGSF9B

4.12e-0519687596e5c6d155273e82ebafa180df8bb589c3e3e54e
ToppCellBronchial-NucSeq-Stromal-Mesofibroblastic-Mesothelia|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MST1 RGS6 TLL1 A4GALT IGSF9B

4.12e-05196875ce13af36fc2932e8125013041742593ff3d07e86
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BMP1 SELENOM ROBO2 MMP16 IGDCC4

4.12e-05196875d5ed41fa111750e6b363c04cccc40a47dd774852
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WDR93 FHAD1 RPGRIP1L SPEF2 DNAH2

4.22e-0519787574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BMP1 ACAN SELENOM ROBO2 MMP16

4.33e-051988751f956e369e00d37835095a001db4b62a79014532
ToppCellcellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT2 GCLC A4GALT CHST9 HSPB1

4.33e-051988756e047de63ef59dcb47e4fc06b173b2a02fdcf4c9
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BMP1 ACAN SELENOM ROBO2 MMP16

4.33e-05198875dc6fbad0ecdd057189f71afcdb6aca25207314a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT2 GCLC A4GALT CHST9 HSPB1

4.33e-0519887589ec1e760a193441092571475cc66a3b425f232e
ToppCellcellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT2 GCLC A4GALT CHST9 HSPB1

4.43e-05199875974f71b56f66243c78f2f297a1540e0e186df530
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WDR93 FHAD1 SPEF2 DNAH2 CHST9

4.54e-05200875926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BMP1 SELENOM ROBO2 MMP16 IGDCC4

4.54e-052008753c898e81444b001835c3f1bbc68183078701b135
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

WDR93 FHAD1 SPEF2 DNAH2 CHST9

4.54e-05200875ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WDR93 FHAD1 SPEF2 DNAH2 CHST9

4.54e-0520087506ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BMP1 SELENOM ROBO2 MMP16 IGDCC4

4.54e-052008753eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

WDR93 FHAD1 SPEF2 DNAH2 CHST9

4.54e-05200875a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WDR93 FHAD1 SPEF2 DNAH2 CHST9

4.54e-05200875918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2G7 KIAA1210 MYOM3 CTH

8.74e-0511987479342c491a214c870ff6215da613db4a28c9d587
ToppCellHippocampus-Macroglia-ASTROCYTE|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2G7 KIAA1210 MYOM3 CTH

8.74e-0511987436857095d4e4cc6428d13bf7de04daec1f4cde1e
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2G7 KIAA1210 MYOM3 CTH

9.32e-051218748334a6b2ced1d6a4808458d6d4232d1b688ba28a
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2G7 KIAA1210 MYOM3 CTH

9.32e-051218744b33eeed7b70da120133b14d42c104d2461d52dc
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2G7 KIAA1210 MYOM3 CTH

9.32e-05121874a33e4ae0b0efb702db1b646ac0486e3b6ce48457
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

KIAA1210 RPGRIP1L MMP16 CAP2

1.16e-041288743ca9ae69fb8cb7f8acb7540aa71778bc917da4df
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH2 ROBO2 MMP16 USH2A

1.92e-04146874c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellLPS-antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WDR93 SETD7 PLS1 CAP2

2.13e-041508749cb3332924bd67c966873343c14445e30d3f384f
ToppCellIIH-Treg-CD4_Treg|IIH / Condition, Cell_class and T cell subcluster

ASXL1 IGSF9B LEF1 IGDCC4

2.36e-04154874d2211a892654b92decb208969040920f7ae8ba1e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 PLA2G7 LILRB3 LILRA6

2.86e-04162874db1e09324e9fdd5e571600cff4f2b1c0cb3c179d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 PLA2G7 LILRB3 LILRA6

2.86e-041628749734943c8b7c04e568792253b7352672a3a5cc58
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 PLA2G7 LILRB3 LILRA6

2.86e-0416287448d7bee271f74b5d06c03c6ae06a662d765a6de3
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 PLA2G7 LILRB3 LILRA6

3.06e-041658744fe7c3c9370a556cf4e308a2e723b4b907a6cc25
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 MYOM3 LILRA6 USH2A

3.06e-04165874ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 PLA2G7 LILRB3 LILRA6

3.06e-041658747f293f64e7df7710b13016937cdd4f1af326f8c3
ToppCelldroplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLGN A4GALT SELENOM XBP1

3.06e-0416587421a82a975f550080b6674750b06212205cd16742
ToppCelldroplet-Thymus-nan-3m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLGN GCM2 LILRA6 RGS11

3.13e-04166874c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BMP1 FHAD1 EGR4 IGSF9B

3.21e-04167874f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

TLL1 XBP1 CHST9 VGLL1

3.21e-041678746efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BMP1 FHAD1 SENP1 PLS1

3.28e-0416887494cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 LILRB3 BPIFB4 LILRA6

3.28e-041688745946204d42307391bc2160abe12850815f350aea
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 LILRB3 PNKP LILRA6

3.35e-041698742341eddfedaad8cee779c37bb87f7def058588ca
ToppCellfacs-Marrow-Granulocytes-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 LILRB3 PNKP LILRA6

3.35e-0416987494871936ccfc73b56d425373b989b87c059d4493
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GCLC GATAD1 ROBO2 LEF1

3.43e-04170874fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CASS4 FAM171A1 GCM2 TLL1

3.43e-041708747fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellfacs-BAT-Fat-24m-Myeloid-granulocyte|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASS4 PLA2G7 LILRB3 LILRA6

3.43e-0417087453916d85f0d6c7e5ef3d900d6ead946f75e32567
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

PLA2G7 FHAD1 LILRB3 LILRA6

3.43e-041708743a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|367C / Donor, Lineage, Cell class and subclass (all cells)

GPR158 BPIFB4 CHST9 FLRT3

3.66e-04173874c2d973356c40e0284fd3bd7733a164b141c66008
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|367C / Donor, Lineage, Cell class and subclass (all cells)

GPR158 BPIFB4 CHST9 FLRT3

3.66e-04173874d8e965ff7e9b758876ec1521c1ccedd739e8d673
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TLL1 A4GALT BPIFB4 CHST9

3.66e-04173874464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PLA2G7 ZMAT5 GEMIN5 PLS1

3.83e-041758742812ac2ef41d245db544697fb6da1883361c96e8
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT2 PLIN5 CCDC120 FAM181B

3.83e-04175874c1a8a55af825d5913095f919fa860828df9c273e
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GCM2 EGR4 ACAN MYOM3

3.83e-04175874f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GCM2 EGR4 ACAN MYOM3

3.83e-041758747bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT2 PLIN5 CCDC120 FAM181B

3.83e-0417587478b453e220218c84557f244ef7a760e4a1952761
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDR93 MST1 FHAD1 SPEF2

4.00e-041778743cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

BMP1 URB1 CANX IGSF9B

4.00e-0417787482fdd6185b368f54f03de389427cbe3071d21a99
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDR93 MST1 FHAD1 SPEF2

4.00e-0417787412a52a12a87a31e501ced611f46a90d172ca7e35
ToppCellfacs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLGN SELENOM MYOM3 XBP1

4.00e-0417787435d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

URB1 TLL1 XBP1 CHST9

4.00e-04177874779ba86f53650772755b52460be03f18bb204e55
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

URB1 TLL1 XBP1 CHST9

4.00e-041778740f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

FHAD1 SPEF2 DNAH2 CHST9

4.00e-04177874c38138fb5ad9766c2d240811210c854338cd612e
ToppCellPCW_13-14-Neuronal-Neuronal_SCP|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CHST9 IGSF9B FLRT3 FAM181B

4.00e-04177874621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A4GALT SELENOM HSPB1 CAP2

4.17e-04179874e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 SPEF2 DNAH2 CES4A

4.17e-041798745e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

PLA2G7 A4GALT ROBO2 IGDCC4

4.17e-041798741526a130565a97c291a25a7a988089bffc1515c1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP24 FAT2 RGS6 GPR158

4.26e-04180874d76349ecef7c5878bf215e946f032264161eb61b
ToppCellfacs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR93 MST1 FHAD1 SPEF2

4.26e-04180874cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

A4GALT MYOM3 CHST9 VGLL1

4.26e-04180874255097d8eb244a32eb2ecd0e7e48e1a20bafb5cd
ToppCellPCW_10-12-Neuronal-Neuronal_postreplicative|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHST9 IGSF9B FLRT3 FAM181B

4.35e-041818741aebb62ed4439db444ee9d30688212b86ee3d9ef
ToppCellPCW_10-12-Neuronal-Neuronal_postreplicative-neuro_NA|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHST9 IGSF9B FLRT3 FAM181B

4.35e-041818746aee2ddee4790250ef3b2ef0038bd9839925c995
ToppCellPCW_10-12-Neuronal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHST9 IGSF9B FLRT3 FAM181B

4.35e-04181874381b553e2cae65ce6be100662a5f9f963353840c
Diseaseinflammatory bowel disease (implicated_via_orthology)

MST1 XBP1 MST1L

4.89e-0525843DOID:0050589 (implicated_via_orthology)
Diseaseleukocyte immunoglobulin-like receptor subfamily A member 6 measurement

LILRB3 LILRA6

1.19e-046842EFO_0801767
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 3 measurement

LILRB3 LILRA6

1.19e-046842EFO_0802705
Diseaseisovalerate measurement

FAM171A1 USH2A

2.85e-049842EFO_0021051
Diseasemyelodysplastic syndrome (implicated_via_orthology)

ASXL1 PRPF8

8.21e-0415842DOID:0050908 (implicated_via_orthology)
Diseaserheumatoid arthritis (is_marker_for)

PLA2G7 ACAN HSPB1

1.02e-0369843DOID:7148 (is_marker_for)
Diseasesmoking cessation

ASXL1 RPGRIP1L RGS6 TNRC6A ROBO2

2.39e-03325845EFO_0004319
Diseaseretinitis pigmentosa (implicated_via_orthology)

PRPF8 USH2A

2.68e-0327842DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PESPQLPWAEYSEPK

AFDN

1141

P55196
PPTPGPVYEQMRSWA

CASS4

106

Q9NQ75
VTTLPPEAFYPIPWQ

A4GALT

276

Q9NPC4
LIDYPLGWPAVSPKP

BPIFB4

391

P59827
PNTVYPAQGQWPAPV

FLRT3

371

Q9NZU0
ESNPWVEKVIYPGLP

CTH

281

P32929
PQGLPWTIPPEEFSK

DIS3L2

356

Q8IYB7
SITSPGWPKEYPPNK

BMP1

601

P13497
PSWNPKIIYEPHPQL

ATG2B

256

Q96BY7
PPWVVKGQPTYQICP

ASXL1

581

Q8IXJ9
PPPHPTQISGYKLYW

IGDCC4

651

Q8TDY8
PPCVYLSGPGWRVKP

RBPJL

91

Q9UBG7
LTPEPVVAPNSPIWY

QRICH1

726

Q2TAL8
EQTYWLVNRPPPGAP

RGS11

186

O94810
YDPLITPAEPSNPWI

RGS6

296

P49758
PKEWIPRPPEKYALS

PAFAH1B1

91

P43034
QITPPLGWQGQPVYP

LEF1

206

Q9UJU2
AWDIPITYGVLPPPR

HCFC1

186

P51610
LWYLETEKPPPPARV

HCFC1

356

P51610
TDPGYPKPITVWKGI

MMP24

506

Q9Y5R2
YVPVAPPTPAWQPEI

LARP1

296

Q6PKG0
PQLGYWVAAMSPPIP

FAM171A1

276

Q5VUB5
TPVSLPKPKSGQWVY

RPGRIP1L

1186

Q68CZ1
ICLPPEWYVVPPGTK

MST1L

591

Q2TV78
AGVWEYPPNPKSRAP

GPBP1

156

Q86WP2
VCPWEVYDLTPGPVP

GPR158

1006

Q5T848
PPTIRWYKDGQPVTP

HMCN2

2676

Q8NDA2
LSTWGPVPYLPPKTM

KIAA1109

4591

Q2LD37
TPWKPPPSDLYGDLK

CCDC120

261

Q96HB5
PALGWIAVSPKPGPY

CAP2

141

P40123
VPVNWSHVNKPPYPA

PLS1

436

Q14651
WEYPHSEVTQGPLPP

FAT2

4191

Q9NYQ8
VYPWNGKRIPGSPEI

IGFBP1

231

P08833
PTGPTIPQPLYLWVK

OR52A4P

286

A6NMU1
VELPKRGYPPDPWIE

PCED1A

271

Q9H1Q7
PPEPWKGIRDATTYP

CES4A

71

Q5XG92
FKPPPPNSDIGWRVE

GCLC

411

P48506
KPCPPEVTPHYIWID

PI4KA

1286

P42356
WPGYVRPLPPAAIES

HSPB1

51

P04792
VQAGPFPKPTLWAEP

LILRA6

21

Q6PI73
VQAGPFPKPTLWAEP

LILRB3

21

O75022
GVGSPEPAPPQLYKW

EGR4

6

Q05215
PPAVVGNLLYPEPWS

FAM181B

311

A6NEQ2
PANWNSPLRPGEKYP

PLA2G7

131

Q13093
EWEPAYTPVGTSPLP

ACAN

741

P16112
ITVYPTDPPKDWPVV

OTULIN

316

Q96BN8
YELVIENPPPVSFPW

FHAD1

91

B1AJZ9
PFPTVPTRPEKGYIW

GATAD1

236

Q8WUU5
PSKGPIPPWLLDIKY

CEP89

351

Q96ST8
TPDAPWCPYKVLPEG

FNDC10

31

F2Z333
EPEGSASPTPPYLKW

AXIN1

71

O15169
PSYQGIWKPRKIPNP

CANX

391

P27824
RSPYTPDEPKEPIWV

APBA1

366

Q02410
PSKYTSPPWVTPKFE

KIAA1210

1081

Q9ULL0
LICLPPEWYVVPPGT

MST1

586

P26927
VPPLWGKAYPSQKPL

DNAH2

4236

Q9P225
WVPACKERPPNYPGS

SACS

1156

Q9NZJ4
VQAGPLPKPTLWAEP

LILRA3

21

Q8N6C8
YVVISWQPPSKPNGP

USH2A

2836

O75445
VPQPPKPGSEEWVYV

SPEF2

1001

Q9C093
DAQVPPEYVWAPAKP

SELENOM

121

Q8WWX9
PEYVWAPAKPPEETS

SELENOM

126

Q8WWX9
NGTITTPGWPKEYPP

TLL1

626

O43897
PSGLITSPNWPDKYP

TLL1

781

O43897
KGLYSPGDLWPTPPV

TMEM131L

1401

A2VDJ0
YPEPWGPPVTVTRAA

GCM2

426

O75603
YEKSFPIKPVPSPSW

SENP1

146

Q9P0U3
PPGKSGPEAPEWYQV

SETD7

341

Q8WTS6
KDPVPYQPPFLCQWG

XBP1

236

P17861
PTGPSDWRILYPEIP

PNKP

186

Q96T60
TPIIGEVWPGLTVYP

SI

461

P14410
WLKQTYPPEHEPSIP

PIK3CB

171

P42338
SILTYWRPVIPGPDP

URB1

2061

O60287
TPWVKGSVPPPLDQY

CLPTM1

251

O96005
PKYKGVWRPPLVDNP

CLGN

366

O14967
VTSGWGPVKYLRPVP

CHST9

51

Q7L1S5
KPADTEPPPLLVYKW

PRPF8

941

Q6P2Q9
FIPWLTLSKPPVPGE

RNF212

201

Q495C1
PYVPEPVPWLKSEIS

TSR1

781

Q2NL82
PGYPKPITVWKGIPE

MMP16

471

P51512
PPYVVEWFKFGVPIP

IGSF9B

56

Q9UPX0
MGQEPRTLPPSPNWY

GEMIN5

1

Q8TEQ6
TPIDSPPVWSPEGYM

PRRC2B

736

Q5JSZ5
PPRGHPEPTIYWKKD

ROBO2

156

Q9HCK4
FPLEVPWKPVFAVSP

WDR93

566

Q6P2C0
PIRTTVFQYPVGWPP

ZMAT5

131

Q9UDW3
VFQYPVGWPPVQELP

ZMAT5

136

Q9UDW3
VQAVPLPWLVGPFAP

PLIN5

366

Q00G26
VWGSERPPVPNQPIY

XPNPEP2

191

O43895
RYSSPWTKPQPEVPV

VGLL1

81

Q99990
EPWKGYPNIDPETDP

TNRC6A

1616

Q8NDV7
EWTMPQPGPPYDVRA

MYOM3

796

Q5VTT5