Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	fn3	EPHB4 BOC TSPOAP1 COL20A1 LRFN3 OBSL1 IGDCC3 IGSF9 FLRT2 EPHA10 EPHA1	1.51e-08	162	128	11	PF00041
Domain	FN3	EPHB4 BOC TSPOAP1 COL20A1 LRFN3 OBSL1 IGDCC3 IGSF9 FLRT2 EPHA10 EPHA1	5.95e-08	185	128	11	SM00060
Domain	FN3	EPHB4 BOC TSPOAP1 COL20A1 LRFN3 OBSL1 IGDCC3 IGSF9 FLRT2 EPHA10 EPHA1	1.25e-07	199	128	11	PS50853
Domain	FN3_dom	EPHB4 BOC TSPOAP1 COL20A1 LRFN3 OBSL1 IGDCC3 IGSF9 FLRT2 EPHA10 EPHA1	2.05e-07	209	128	11	IPR003961
Domain	EGF-like_CS	EPHB4 ADAM19 CELSR1 HMCN2 MEGF8 TENM3 TLL1 LTBP2 EPHA10 CRB2 EPHA1	1.85e-06	261	128	11	IPR013032
Domain	EGF_2	EPHB4 ADAM19 CELSR1 HMCN2 MEGF8 TENM3 TLL1 LTBP2 EPHA10 CRB2 EPHA1	2.14e-06	265	128	11	PS01186
Domain	EGF-type_Asp/Asn_hydroxyl_site	CELSR1 HMCN2 MEGF8 TLL1 LTBP2 CRB2	8.98e-05	106	128	6	IPR000152
Domain	Growth_fac_rcpt_	EPHB4 CELSR1 HMCN2 MEGF8 LTBP2 PCSK4 EPHA1	1.01e-04	156	128	7	IPR009030
Domain	RECEPTOR_TYR_KIN_V_2	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	PS00790
Domain	Tyr_kinase_rcpt_V_CS	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	IPR001426
Domain	EphA2_TM	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	IPR001090
Domain	Eph_TM	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	IPR027936
Domain	EPH_lbd	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	SM00615
Domain	Ephrin_lbd	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	IPR016257
Domain	EPH_LBD	EPHB4 EPHA10 EPHA1	1.08e-04	14	128	3	PS51550
Domain	EGF_CA	CELSR1 HMCN2 MEGF8 TLL1 LTBP2 CRB2	1.95e-04	122	128	6	SM00179
Domain	EGF-like_Ca-bd_dom	CELSR1 HMCN2 MEGF8 TLL1 LTBP2 CRB2	2.13e-04	124	128	6	IPR001881
Domain	EGF_3	ADAM19 CELSR1 HMCN2 MEGF8 TENM3 TLL1 LTBP2 CRB2	2.18e-04	235	128	8	PS50026
Domain	EGF-like_dom	ADAM19 CELSR1 HMCN2 MEGF8 TENM3 TLL1 LTBP2 CRB2	3.22e-04	249	128	8	IPR000742
Domain	Ig-like_fold	EPHB4 BOC EPM2A TSPOAP1 COL20A1 LRFN3 MMP23B OBSL1 IGDCC3 HMCN2 IGSF9 FLRT2 EPHA10 EPHA1	3.48e-04	706	128	14	IPR013783
Domain	EGF_1	ADAM19 CELSR1 HMCN2 MEGF8 TENM3 TLL1 LTBP2 CRB2	3.78e-04	255	128	8	PS00022
Domain	EGF_Ca-bd_CS	HMCN2 MEGF8 TLL1 LTBP2 CRB2	5.44e-04	97	128	5	IPR018097
Domain	EGF_CA	HMCN2 MEGF8 TLL1 LTBP2 CRB2	5.98e-04	99	128	5	PS01187
Domain	ASX_HYDROXYL	CELSR1 HMCN2 MEGF8 LTBP2 CRB2	6.26e-04	100	128	5	PS00010
Domain	-	EPHB4 BOC EPM2A TSPOAP1 COL20A1 LRFN3 MMP23B OBSL1 IGDCC3 IGSF9 FLRT2 EPHA10 EPHA1	6.33e-04	663	128	13	2.60.40.10
Domain	Ephrin_rec_like	EPHB4 EPHA10 EPHA1	6.48e-04	25	128	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB4 EPHA10 EPHA1	6.48e-04	25	128	3	IPR011641
Domain	K_chnl_volt-dep_Kv9	KCNG3 KCNS1	9.57e-04	7	128	2	IPR003971
Domain	Peptidase_Metallo	MMP23B TLL1 MMP11	1.01e-03	29	128	3	IPR006026
Domain	ZnMc	MMP23B TLL1 MMP11	1.01e-03	29	128	3	SM00235
Domain	-	MBD3 BAZ2A	1.27e-03	8	128	2	3.30.890.10
Domain	-	EPHB4 PCSK4 EPHA10 EPHA1	1.59e-03	73	128	4	2.60.120.260
Domain	Pkinase_Tyr	EPHB4 NPR1 TGFBR2 EPHA10 EPHA1	1.95e-03	129	128	5	PF07714
Domain	Ig_I-set	BOC LRFN3 OBSL1 IGDCC3 HMCN2 IGSF9	1.99e-03	190	128	6	IPR013098
Domain	I-set	BOC LRFN3 OBSL1 IGDCC3 HMCN2 IGSF9	1.99e-03	190	128	6	PF07679
Domain	-	ADAM19 MMP23B TLL1 MMP11	2.33e-03	81	128	4	3.40.390.10
Domain	MetalloPept_cat_dom	ADAM19 MMP23B TLL1 MMP11	2.33e-03	81	128	4	IPR024079
Domain	-	TPP1 PCSK4	2.46e-03	11	128	2	3.40.50.200
Domain	MBD	MBD3 BAZ2A	2.46e-03	11	128	2	SM00391
Domain	MBD	MBD3 BAZ2A	2.46e-03	11	128	2	PS50982
Domain	Peptidase_S8/S53_dom	TPP1 PCSK4	2.46e-03	11	128	2	IPR000209
Domain	Methyl_CpG_DNA-bd	MBD3 BAZ2A	2.46e-03	11	128	2	IPR001739
Domain	MBD	MBD3 BAZ2A	2.46e-03	11	128	2	PF01429
Domain	DNA-bd_dom	MBD3 BAZ2A	2.46e-03	11	128	2	IPR016177
Domain	Peptidase_S8	TPP1 PCSK4	2.46e-03	11	128	2	PF00082
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPHB4 SHROOM3 MYO9B RHOT2 LRRK1 KDM6B ABCA7 MBD3 RYR1 TAOK2 CELSR1 WIZ MROH6 MEGF8 IFRD2 TMEM132A KBTBD11 KIFC3 MAPKBP1 CHPF ESPL1	1.46e-09	1105	133	21	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZHX3 TSPOAP1 TRO OBSL1 ARHGEF17 USP19 MEGF8 TENM3 BAZ2A MAST1 MAPKBP1	5.19e-07	407	133	11	12693553
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DENND2A SHROOM3 TRIOBP LRRK1 KDM6B ZFYVE1 TAOK2 KBTBD11 IGSF9 PLAGL2 ESPL1	6.46e-06	529	133	11	14621295
Pubmed	ABCA7 and EphA1 Genes Polymorphisms in Late-Onset Alzheimer's Disease.	ABCA7 EPHA1	1.45e-05	2	133	2	31659653
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EPRS1 ZSWIM8 EGLN2 DCAF6 ADAM19 APC2 OBSL1 TRIOBP WHAMM KDM6B WIZ TPP1 MAST1 KIFC3 CHPF PBXIP1	3.40e-05	1285	133	16	35914814
Pubmed	EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells.	ARHGEF15 EPHA1	4.34e-05	3	133	2	12775584
Pubmed	Susceptible gene single nucleotide polymorphism and hemorrhage risk in patients with brain arteriovenous malformation.	TGFBR2 LTBP2	4.34e-05	3	133	2	21737283
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB4 NPR1 ABCA7 USP19 PDIA6 CELSR1 MEGF8 TENM3 TLL1 TMEM132A LTBP2 EIF3A CHPF PBXIP1 MAN1B1	5.86e-05	1201	133	15	35696571
Pubmed	Use of denaturing HPLC to map human and murine genes and to validate single-nucleotide polymorphisms.	ABCA7 CFD	8.67e-05	4	133	2	10769753
Pubmed	Restoring Endothelial Function by Targeting Desert Hedgehog Downstream of Klf2 Improves Critical Limb Ischemia in Adults.	KLF2 SMO	8.67e-05	4	133	2	30355159
Pubmed	A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development.	MEGF8 SMO	1.44e-04	5	133	2	32966817
Pubmed	Transcriptional regulation of mouse L-selectin.	KLF2 MZF1	2.16e-04	6	133	2	19041738
Pubmed	Gene expression in the developing mouse retina by EST sequencing and microarray analysis.	XYLT1 WIZ TENM3 KBTBD11 FLRT2	2.23e-04	142	133	5	11812828
Pubmed	Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.	TGFBR2 LTBP2 MMP11	3.56e-04	36	133	3	20587546
Pubmed	Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.	CFD PCSK4	4.00e-04	8	133	2	7782070
Pubmed	Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.	ABCA7 EPHA1	4.00e-04	8	133	2	21460840
Pubmed	Pervasive translational regulation of the cell signalling circuitry underlies mammalian development.	SAV1 SMO	4.00e-04	8	133	2	28195124
Pubmed	Neuropeptide Y receptor genes on human chromosome 4q31-q32 map to conserved linkage groups on mouse chromosomes 3 and 8.	MYO9B TLL1	4.00e-04	8	133	2	9169155
Pubmed	Importance of Endogenous Atrial and Brain Natriuretic Peptides in Murine Embryonic Vascular and Organ Development.	NPR1 KLF2	4.00e-04	8	133	2	26517044
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	BOC LRFN3 OBSL1 IGDCC3 IGSF9	4.10e-04	162	133	5	25826454
Pubmed	Mutation of ARHGAP9 in patients with coronary spastic angina.	MYO9B ARHGEF17 ARHGEF15	4.18e-04	38	133	3	19911011
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	TENM3 IGSF9 EPHA10 EPHA1	4.22e-04	91	133	4	28558017
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	GALNTL6 EPRS1 IGDCC3 EVPL ARHGEF17 RYR1 CHRNB4 WIZ EIF3A TMEM200C	5.54e-04	736	133	10	29676528
Pubmed	DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.	DCAF6 PHF1 GTF2I EIF3A	5.81e-04	99	133	4	34161765
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZSWIM8 ARHGEF15 USP19 TAOK2	6.03e-04	100	133	4	10048485
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SHROOM3 TRIOBP WHAMM MBD3 TAOK2 PDIA6 CELSR1 WIZ BAZ2A TPP1 CRACDL IFRD2 EIF3A PBXIP1 MAN1B1	6.25e-04	1497	133	15	31527615
Pubmed	Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate.	EPHA10 EPHA1	6.40e-04	10	133	2	25073978
Pubmed	Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice.	EPHB4 SMO	6.40e-04	10	133	2	18568073
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM3 FLRT2	6.40e-04	10	133	2	38713721
Pubmed	EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes.	EPHA10 EPHA1	6.40e-04	10	133	2	16547242
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	MBD3 WIZ BAZ2A DDX24	6.74e-04	103	133	4	32744500
Pubmed	Mapping of transcription start sites of human retina expressed genes.	FSCN2 KIFC3 CRB2	6.90e-04	45	133	3	17286855
Pubmed	Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.	ABCA7 EPHA1	7.80e-04	11	133	2	21460841
Pubmed	Gas1 is a receptor for sonic hedgehog to repel enteric axons.	BOC SMO	7.80e-04	11	133	2	25535338
Pubmed	Sonic hedgehog signaling regulates actin cytoskeleton via Tiam1-Rac1 cascade during spine formation.	MAST1 SMO	7.80e-04	11	133	2	20654717
Pubmed	Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.	EPHB4 EPHA10 EPHA1	9.96e-04	51	133	3	19769959
Pubmed	The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2.	MBD3 EIF3A	1.10e-03	13	133	2	12124384
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZSWIM8 DCAF6 PLCXD1 OBSL1 RHOT2 ABCA7 MBD3 FCSK HMCN2 WIZ BAZ2A DDX24	1.23e-03	1116	133	12	31753913
Pubmed	Spatiotemporal regulation of GLI target genes in the mammalian limb bud.	SHROOM3 IGDCC3 IER5 EDNRB SMO	1.23e-03	207	133	5	26238476
Pubmed	Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.	XYLT1 SMO	1.28e-03	14	133	2	19666503
Pubmed	Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue.	EPHB4 EPHA1	1.28e-03	14	133	2	26941654
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	ZSWIM8 APC2 TRIOBP MEGF8 IGSF9 EIF3A GRIP2 MAPKBP1	1.45e-03	560	133	8	21653829
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	BOC LRFN3 TAOK2 FCSK TPP1 PRRT3 IGSF9 FLRT2 CHPF PCSK4 MAN1B1	1.46e-03	985	133	11	12975309
Pubmed	Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength.	MEGF8 SMO	1.48e-03	15	133	2	34486668
Pubmed	A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.	BOC SMO	1.48e-03	15	133	2	25458012
Pubmed	Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.	MBD3 EIF3A	1.48e-03	15	133	2	9804427
Pubmed	Defects in pulmonary vasculature and perinatal lung hemorrhage in mice heterozygous null for the Forkhead Box f1 transcription factor.	EDNRB KLF2	1.68e-03	16	133	2	11437453
Pubmed	Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1.	MBD3 EIF3A	1.68e-03	16	133	2	11102443
Pubmed	Matrix metalloproteinases in tumor invasion.	MMP23B MMP11	1.68e-03	16	133	2	10949577
Pubmed	Genomic analysis of mouse retinal development.	ZSWIM8 BTBD17 FJX1 RHOT2 TAOK2 BAZ2A KCNJ14 KBTBD11 MAST1 IGSF9 PCSK4	1.72e-03	1006	133	11	15226823
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ZHX3 OBSL1 TRIOBP ARHGEF15 GRIP2	1.78e-03	225	133	5	12168954
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	EVPL DNPH1 F11 RYR1 CFD WIZ MEGF8 TPP1 SMO KIFC3 CRB2	1.86e-03	1016	133	11	19056867
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHB4 EPHA1	1.90e-03	17	133	2	12217323
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	ZHX3 WDR33 MBD3 TAOK2 WIZ BAZ2A	2.06e-03	341	133	6	32971831
Pubmed	The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.	MBD3 EIF3A	2.13e-03	18	133	2	9790534
Pubmed	TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.	PHF1 GTF2I	2.13e-03	18	133	2	28068325
Pubmed	A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.	PHF1 WIZ	2.13e-03	18	133	2	29628311
Pubmed	Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.	MBD3 EIF3A	2.13e-03	18	133	2	10444591
Pubmed	Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.	KLF2 SMO	2.13e-03	18	133	2	30352852
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	EPRS1 PDIA6 GTF2I EIF3A	2.21e-03	142	133	4	30809309
Pubmed	ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas.	TGFBR2 HSF4 ESPL1 TMEM200C	2.21e-03	142	133	4	30232004
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	MLNR RYR1 KCNJ14 LTBP2	2.27e-03	143	133	4	20424473
Pubmed	Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.	SMO FLRT2	2.38e-03	19	133	2	34433966
Pubmed	Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02).	RNF39 GPANK1	2.38e-03	19	133	2	19115949
Pubmed	Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development.	EPHB4 SMO	2.38e-03	19	133	2	18725519
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	EPRS1 RHOT2 PDIA6 GTF2I MEGF8 TPP1 EIF3A CHPF	2.55e-03	613	133	8	22268729
Pubmed	Multiple roles of EPH receptors and ephrins in neural development.	EPHB4 EPHA1	2.64e-03	20	133	2	11256076
Pubmed	The ephrins and Eph receptors in neural development.	EPHB4 EPHA1	2.64e-03	20	133	2	9530499
Pubmed	Eph receptors and ephrins: effectors of morphogenesis.	EPHB4 EPHA1	2.64e-03	20	133	2	10207129
Pubmed	SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects.	SHROOM3 CELSR1	2.64e-03	20	133	2	32511952
Pubmed	The Eph family receptors and ligands.	EPHB4 EPHA1	2.64e-03	20	133	2	9576626
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	LRRK1 CELSR1 TPP1	2.69e-03	72	133	3	25917818
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	MBD3 GTF2I WIZ BAZ2A	2.69e-03	150	133	4	28242625
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	EPHB4 DNPH1 B3GNT8 CFD MEGF8 TPP1 TMEM132A SMO LTBP2 FLRT2 CRB2	2.77e-03	1070	133	11	23533145
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	DENND2A NUDT22 KCNG3 JSRP1 RYR1 KLF2 ZNF16 TLL1 DACT3 ZNF654	2.79e-03	915	133	10	32393512
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	ZHX3 EDNRB TGFBR2 SMO FLRT2	2.86e-03	251	133	5	29031500
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHB4 EPHA1	2.91e-03	21	133	2	9267020
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHB4 EPHA1	2.91e-03	21	133	2	10495276
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHB4 EPHA1	2.91e-03	21	133	2	20112066
Pubmed	Nephronophthisis-Related Ciliopathies	XPNPEP3 MAPKBP1	2.91e-03	21	133	2	27336129
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHB4 EPHA1	2.91e-03	21	133	2	11128993
Pubmed	Hedgehog-GLI signaling in Foxd1-positive stromal cells promotes murine nephrogenesis via TGFβ signaling.	TGFBR2 SMO	2.91e-03	21	133	2	29945868
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHB4 EPHA1	2.91e-03	21	133	2	10730216
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KDM6B MBD3 PHF1 BAZ2A	3.17e-03	157	133	4	30186101
Pubmed	Functional interactions between matrix metalloproteinases and glycosaminoglycans.	MMP23B MMP11	3.19e-03	22	133	2	23421805
Pubmed	Matrix metalloproteinases.	MMP23B MMP11	3.19e-03	22	133	2	10419448
Pubmed	Klf2 is an essential regulator of vascular hemodynamic forces in vivo.	EPHB4 KLF2	3.19e-03	22	133	2	17141159
Pubmed	Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.	ZHX3 GTF2I WIZ	3.25e-03	77	133	3	19505873
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	EPRS1 ZHX3 RNF113A MBD3 PDIA6 GTF2I WIZ	3.42e-03	506	133	7	30890647
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	EPHB4 EPRS1 OBSL1 RHOT2 USP19 TAOK2 PDIA6 CHPF ESPL1 MAN1B1	3.43e-03	942	133	10	31073040
Pubmed	Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.	EPHB4 EPHA1	3.48e-03	23	133	2	19542359
Pubmed	Genome-wide identification of endothelial cell-enriched genes in the mouse embryo.	ARHGEF15 EXOC3L1	3.48e-03	23	133	2	22535667
Pubmed	Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung.	EPHB4 KLF2	3.48e-03	23	133	2	33830085
Pubmed	Primary cilia in murine palatal rugae development.	CELSR1 SMO	3.48e-03	23	133	2	31226309
Pubmed	Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.	MMP23B MMP11	3.79e-03	24	133	2	15734845
Pubmed	Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium.	EPHB4 TGFBR2	3.79e-03	24	133	2	25497097
Pubmed	Genomic screen for genes involved in mammalian craniofacial development.	TRO IGDCC3	3.79e-03	24	133	2	12533789
Pubmed	Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping.	GNB1L TRIOBP	3.79e-03	24	133	2	11258795
Pubmed	Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses.	XYLT1 HSF4	3.79e-03	24	133	2	18755693
Pubmed	Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis.	EPHB4 TGFBR2	3.79e-03	24	133	2	25382630
Interaction	FIBIN interactions	ADAM19 CFD CELSR1 MEGF8 TMEM132A PBXIP1	5.44e-06	71	126	6	int:FIBIN
Interaction	SDF2L1 interactions	EPHB4 ADAM19 LRFN3 RIOX1 CFD PDIA6 CELSR1 MEGF8 TMEM132A PBXIP1 EPHA10	5.80e-06	322	126	11	int:SDF2L1
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	MYO9B APC2 MISP3 JSRP1 ABCA7 MBD3 KLF2 CFD WIZ MAST1 PCSK4	2.23e-05	797	133	11	chr19p13
Cytoband	19p13.3	APC2 JSRP1 ABCA7 MBD3 CFD PCSK4	7.05e-05	237	133	6	19p13.3
Cytoband	17p13.1	SPEM2 KDM6B KCTD11 ARHGEF15	4.00e-04	118	133	4	17p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	EGLN2 LRFN3 RYR1 B3GNT8 ZSWIM9 MEGF8 MZF1 KCNJ14 PNMA8A DACT3 SBK2	7.31e-04	1192	133	11	chr19q13
GeneFamily	Fibronectin type III domain containing	EPHB4 BOC TSPOAP1 COL20A1 LRFN3 IGDCC3 IGSF9 FLRT2 EPHA10 EPHA1	9.55e-09	160	93	10	555
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB4 EPHA10 EPHA1	4.60e-05	14	93	3	1095
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	BOC LRFN3 OBSL1 IGDCC3 HMCN2 IGSF9	1.83e-04	161	93	6	593
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	MBD3 BAZ2A	1.40e-03	11	93	2	1025
Coexpression	GARCIA_PINERES_PBMC_HPV_16_L1_VLP_AGE_18_25YO_2MO_DN	MYO9B GNB1L F11 KLF2 CFD CELSR1 MZF1 KCNJ14 FLRT2 KIFC3	2.04e-06	287	132	10	M40958
Coexpression	DESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS	BOC EVPL CSDC2 TENM3 CRACDL TLL1 PNMA8A TMEM132A IGSF9 CRB2	4.41e-06	313	132	10	M40228
Coexpression	MARTENS_TRETINOIN_RESPONSE_UP	SPEM2 CCDC185 COL20A1 MLNR LRFN3 OR8S1 KCTD11 ARHGEF15 CHRNB4 B3GNT8 NLRP6 HMCN2 IGSF9 MMP11 PCSK4 SBK2	6.60e-06	855	132	16	M2098
Coexpression	IBRAHIM_NRF2_DOWN	EPRS1 PLCXD1 OBSL1 FJX1 RHOT2 ABCA7 PBXIP1	2.36e-05	168	132	7	M42513
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL3	BOC SHROOM3 TSPOAP1 OBSL1 FJX1 EDNRB SORCS1 CELSR1 TPP1 CHPF PBXIP1 CRB2	3.49e-05	574	132	12	M39056
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	BOC DENND2A SHROOM3 TSPOAP1 IGDCC3 FJX1 KDM6B KCTD11 ARHGEF17 ABCA7 PHF1 ZSWIM9 MZF1 PNMA8A TMEM132A IGSF9 PLAGL2 SMO LTBP2 LOXL3 PBXIP1 CRB2	5.91e-07	1075	130	22	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)\|390C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 DENND2A NPR1 EDNRB TLL1 KBTBD11 EXOC3L1 FLRT2	1.00e-07	188	133	8	aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 DENND2A NPR1 EDNRB TLL1 KBTBD11 EXOC3L1 FLRT2	1.00e-07	188	133	8	1f40b959777d18ad88d239df8cca304f062ba04c
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	MMP23B DNM1P46 ARHGEF15 CSDC2 KLF2 HMCN2 DACT3 LTBP2	1.00e-07	188	133	8	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CSDC2 ZNF16 KCNJ14 TMEM132A EXOC3L1 MMP11 TMEM200C	7.48e-07	168	133	7	53a982869dbf14f6a948589be9f2f3df3b9a7e97
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EPHB4 NPR1 TRIOBP IGDCC3 EDNRB KLF2 TLL1	1.10e-06	178	133	7	0139b42494c1186390b12106dea7957e2b6717c2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTBD17 FJX1 CSDC2 EDNRB CELSR1 TENM3 PBXIP1	1.83e-06	192	133	7	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	facs-Mammary_Gland\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHROOM3 IER5 KDM6B KCTD11 CSDC2 TMEM132A LTBP2	2.02e-06	195	133	7	21cfcb751e548591fc8724a8329c294da6012e0f
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 DENND2A ADAM19 EDNRB TLL1 KBTBD11 FLRT2	2.32e-06	199	133	7	1587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 DENND2A ADAM19 EDNRB TLL1 KBTBD11 FLRT2	2.32e-06	199	133	7	a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte\|10w / Sample Type, Dataset, Time_group, and Cell type.	BOC BTBD17 DNPH1 EDNRB PDIA6 PBXIP1 CRB2	2.39e-06	200	133	7	75f5ea38fbd341b80a8058077a04447f0e0eea28
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 DENND2A ADAM19 EDNRB TLL1 KBTBD11 FLRT2	2.39e-06	200	133	7	c59f262b2b0a7e7dcb2940d1e466f98db6c56625
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 DENND2A ADAM19 EDNRB TLL1 KBTBD11 FLRT2	2.39e-06	200	133	7	e50ef394e3284a8323bfd60575b262b2be422aea
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BOC MMP23B CSDC2 TENM3 DACT3 SMO LTBP2	2.39e-06	200	133	7	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_D\|E18.5-samps / Age Group, Lineage, Cell class and subclass	MMP23B IER5 KCTD11 TENM3 LTBP2 FLRT2	5.78e-06	149	133	6	dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	DENND2A LRFN3 C20orf144 CSDC2 CFD LTBP2	1.00e-05	164	133	6	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TSPOAP1 TRIOBP CELSR1 MEGF8 LTBP2 MAPKBP1	1.15e-05	168	133	6	2fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL20A1 IGDCC3 CHRNB4 SORCS1 GRIP2 TMEM200C	1.27e-05	171	133	6	b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2A TRO MMP23B JSRP1 ARHGEF15 CRB2	1.31e-05	172	133	6	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	EVPL RYR1 CRACDL TLL1 IGSF9 CRB2	1.36e-05	173	133	6	3d7c281a1a9f183a5a861d1a9c7b50d216535893
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	EVPL RYR1 CRACDL TLL1 IGSF9 CRB2	1.36e-05	173	133	6	3aa90578371039f81b7c6fa873ec70f8f2bc7dfa
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNTL6 NPR1 ARHGEF15 KLF2 TGFBR2 EXOC3L1	1.50e-05	176	133	6	dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DENND2A SHROOM3 ARHGEF17 FSCN2 LTBP2 LOXL3	1.65e-05	179	133	6	f5bb4d3a27d56698473219970e764084096cc582
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DENND2A SHROOM3 ARHGEF17 FSCN2 LTBP2 LOXL3	1.65e-05	179	133	6	fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2A SHROOM3 ARHGEF17 FSCN2 LTBP2 LOXL3	1.70e-05	180	133	6	f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCell	droplet-Lung-nan-18m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2A SHROOM3 ARHGEF17 FSCN2 LTBP2 LOXL3	1.70e-05	180	133	6	dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAM19 ARHGEF15 KLF2 TLL1 KBTBD11 FLRT2	1.86e-05	183	133	6	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2A TRO MMP23B LOXL3 FLRT2 CRB2	1.92e-05	184	133	6	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TSPOAP1 PLCXD1 EVPL XYLT1 CELSR1 EPHA1	1.98e-05	185	133	6	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM19 EDNRB TGFBR2 TENM3 KBTBD11 FLRT2	2.04e-05	186	133	6	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DCAF6 LRRK1 SORCS1 CRACDL KCNS1 FLRT2	2.04e-05	186	133	6	bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP23B EVPL ARHGEF17 MMP11 CHPF NKAPL	2.11e-05	187	133	6	b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP23B EVPL ARHGEF17 MMP11 CHPF NKAPL	2.11e-05	187	133	6	9fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCell	tumor_Lung-Endothelial_cells-Lymphatic_ECs\|tumor_Lung / Location, Cell class and cell subclass	TRIOBP EDNRB TENM3 KBTBD11 EXOC3L1 FLRT2	2.11e-05	187	133	6	87ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NPR1 ARHGEF15 EDNRB KLF2 TLL1	2.11e-05	187	133	6	f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP23B EVPL ARHGEF17 MMP11 CHPF NKAPL	2.11e-05	187	133	6	e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 NPR1 ARHGEF15 EDNRB KLF2 TLL1	2.11e-05	187	133	6	fa71f9220b288ed6a1d06f347fec42649aac1f13
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 TGFBR2 CELSR1 TLL1 KBTBD11 TMEM200C	2.30e-05	190	133	6	a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 TGFBR2 CELSR1 TLL1 KBTBD11 TMEM200C	2.30e-05	190	133	6	0bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHB4 TGFBR2 CELSR1 TLL1 KBTBD11 TMEM200C	2.30e-05	190	133	6	26e2237f65cb43723c5da853831b40df2982d6e4
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBR2 CELSR1 TLL1 KBTBD11 RNF39 TMEM200C	2.37e-05	191	133	6	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BOC KLF2 TENM3 KCNS1 FLRT2 CHPF	2.37e-05	191	133	6	273c4a757292a9301de0eaeacdec91c9866be229
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTBD17 FJX1 CSDC2 EDNRB CELSR1 PBXIP1	2.37e-05	191	133	6	fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EPHB4 NPR1 LRFN3 ARHGEF15 EXOC3L1 FLRT2	2.37e-05	191	133	6	dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBR2 CELSR1 TLL1 KBTBD11 RNF39 TMEM200C	2.37e-05	191	133	6	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC ARHGEF15 KLF2 TGFBR2 TLL1 FLRT2	2.44e-05	192	133	6	1ee4783051ec94ea94600f040edcb385fc4289f1
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ARHGEF15 EDNRB KLF2 EXOC3L1 MMP11	2.44e-05	192	133	6	1a2dd398141069ef6ad2f6bb4bae0bac1c6b98e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB4 ARHGEF15 KLF2 TGFBR2 TLL1 FLRT2	2.44e-05	192	133	6	25cb6cc6cbf8dc20139d938adfc02ed7a8c3dfb6
ToppCell	droplet-Kidney-KIDNEY-1m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPR1 ARHGEF15 EDNRB KLF2 EXOC3L1 MMP11	2.44e-05	192	133	6	5dd206adb8b84c374ee931f7df2a8b8cf040efab
ToppCell	droplet-Kidney-nan-3m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 BOC NPR1 ARHGEF15 EDNRB EXOC3L1	2.44e-05	192	133	6	85be54c2cba8eab4c6ef2a85a526f7a9db4cfe73
ToppCell	droplet-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB4 BOC NPR1 ARHGEF15 EDNRB EXOC3L1	2.44e-05	192	133	6	31a9142d97b690992aabee1a181650deb1a44253
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP23B SMO LOXL3 FLRT2 CHPF PBXIP1	2.44e-05	192	133	6	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPRS1 ADAM19 DNPH1 JSRP1 PDIA6 CHPF	2.52e-05	193	133	6	43ffa8ecc72bebcd204279db2bde98ae48d97f90
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR1 LRFN3 ARHGEF15 EDNRB EXOC3L1 RNF39	2.59e-05	194	133	6	8a4be91414a2e69dd410aa75791f16008204c9a1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-Plasma_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPRS1 ADAM19 DNPH1 JSRP1 PDIA6 CHPF	2.59e-05	194	133	6	297286c57d7ee6338d9cf77b27eb2809378ce15d
ToppCell	TCGA-Blood_and_Bone_Marrow-Primary_Tumor-Diffuse_large_B-cell_lymphoma-DLBCL-1\|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9	BOC ADAM19 ARHGEF15 TENM3 TLL1 LTBP2	2.59e-05	194	133	6	eaeeb84576270cc3fc59002ba33bff9639bb0b02
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	BOC ARHGEF15 KLF2 TGFBR2 TLL1 FLRT2	2.74e-05	196	133	6	ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A ADAM19 EDNRB TLL1 KBTBD11 FLRT2	2.74e-05	196	133	6	09a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A ADAM19 EDNRB TLL1 KBTBD11 FLRT2	2.74e-05	196	133	6	e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB4 ARHGEF15 KLF2 TGFBR2 TLL1 FLRT2	2.74e-05	196	133	6	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB4 BOC ARHGEF15 KLF2 TGFBR2 FLRT2	2.82e-05	197	133	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC ARHGEF15 KLF2 TGFBR2 TLL1 FLRT2	2.82e-05	197	133	6	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	(4)_Endothelial_cells\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	NPR1 ARHGEF15 EDNRB KLF2 TGFBR2 TLL1	2.82e-05	197	133	6	dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell	Parenchymal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TRO LRFN3 MMP23B TENM3 LTBP2 CRB2	2.90e-05	198	133	6	0cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB4 BOC ARHGEF15 TGFBR2 TLL1 FLRT2	2.90e-05	198	133	6	259fbcc0f2ac281a3e4d693de45b986fe5e24841
ToppCell	Parenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TRO LRFN3 MMP23B TENM3 LTBP2 CRB2	2.90e-05	198	133	6	e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	BOC OBSL1 DNPH1 EDNRB PDIA6 CRB2	2.99e-05	199	133	6	75ff9a5df156c6632883eab79573f1c02c985803
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BOC MMP23B DACT3 LTBP2 GRIP2 FLRT2	2.99e-05	199	133	6	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	BOC SAV1 XYLT1 CELSR1 WIZ TPP1	2.99e-05	199	133	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Kidney-Endothelial\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	EPHB4 NPR1 ARHGEF15 KLF2 TGFBR2 EXOC3L1	2.99e-05	199	133	6	b543f0686522df43737e9ffa5c9733e42b8a9f4d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Glia_progenitor_cell\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	EGLN2 BTBD17 DNPH1 C20orf144 B3GNT8 PBXIP1	3.07e-05	200	133	6	859f98f63797087e7df18be632de153009b6cab1
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EPHB4 NPR1 ARHGEF15 EDNRB EXOC3L1 FLRT2	3.07e-05	200	133	6	77ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte\|3m / Sample Type, Dataset, Time_group, and Cell type.	BOC OBSL1 BTBD17 EDNRB PBXIP1 CRB2	3.07e-05	200	133	6	98d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Macroglial-Astrocyte\|2m / Sample Type, Dataset, Time_group, and Cell type.	OBSL1 BTBD17 EDNRB PDIA6 CHPF CRB2	3.07e-05	200	133	6	4cf46f1e362da4ef7399b01b28c011f0b3bd2815
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 DENND2A EDNRB TGFBR2 KBTBD11 EXOC3L1	3.07e-05	200	133	6	b515b2ab0c3f5928dd67f2f227fc932451c272bb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-BMP_responsible_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	PIK3AP1 LRRK1 RYR1 KLF2 TGFBR2 TPP1	3.07e-05	200	133	6	26251ed8c7fa7e87973d6f59bd398c88ad025395
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial\|10w / Sample Type, Dataset, Time_group, and Cell type.	BOC OBSL1 DNPH1 EDNRB PDIA6 CRB2	3.07e-05	200	133	6	bda719369aa199902789061e223b129f70a1317a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	OBSL1 BTBD17 DNPH1 EDNRB PBXIP1 CRB2	3.07e-05	200	133	6	ed4a41cb6782541d8fc928aaa12cf03bc1c630a2
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB4 DENND2A EDNRB TGFBR2 KBTBD11 EXOC3L1	3.07e-05	200	133	6	35f6c7f2469d12748c27f2a5d4a161ef839b4a07
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C15orf62 RYR1 CSDC2 KCNS1 RNF39	4.97e-05	133	133	5	f7d0763b5eec2db33044d6850fd57462494038c1
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CCDC185 COL20A1 MISP3 FSCN2	5.44e-05	69	133	4	3da27f504e82277fa4a8fb67d60fc26dee0a414f
ToppCell	droplet-Liver-Npc-21m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F11 MEGF8 NKAPL ZNF654	6.08e-05	71	133	4	cf4c8715c2bd77fc86e45cc01bcc7aa6044e091d
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DNPH1 TPP1 IGSF9 PLAGL2 PBXIP1	9.35e-05	152	133	5	6d02b50e9e9ecf820f84a79e46d153a4840a1cfe
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	MMP23B KLF2 PHF1 MZF1 PCSK4	1.03e-04	155	133	5	a4f2fffa8d0de760c556c3f8f1c91804eedbfa68
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BOC KLF2 IGSF9 RNF39 TMEM200C	1.12e-04	158	133	5	c8af8964a140acb2987e3b4906d72c546108d229
ToppCell	IIF-Lymphocyte-T_NK-ILC\|IIF / Disease, Lineage and Cell Type	EPHB4 ZFYVE1 LINC02902 HSF4 CHPF	1.16e-04	159	133	5	55e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAM19 ARHGEF17 MEGF8 GRIP2 MMP11	1.30e-04	163	133	5	8f24cef152f5965727bbeee116bd26c75cbba82a
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	ADAM19 COL20A1 SORCS1 CRACDL IGSF9	1.30e-04	163	133	5	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK1 CRACDL KBTBD11 KIFC3 CHPF	1.34e-04	164	133	5	9fed5df40f50bde35db8bf89c291cbdc0e104112
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNTL6 JSRP1 RYR1 CRACDL MAST1	1.37e-04	165	133	5	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNTL6 JSRP1 RYR1 CRACDL MAST1	1.37e-04	165	133	5	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GALNTL6 RYR1 KCNS1 IGSF9	1.40e-04	88	133	4	b4620e79ea80681305434707e87cb02a7c6a5e4f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GALNTL6 RYR1 KCNS1 IGSF9	1.40e-04	88	133	4	7992f8e621edf464bffcb70a6cc5f3b60c1d96f8
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Rln3_(parabrachial_pigmented_nucleus_(PBP))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GALNTL6 RYR1 KCNS1 IGSF9	1.40e-04	88	133	4	b7b55f51af8ffa82813a4747580985a430da9ed1
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNTL6 C15orf62 TRO ZFP92 HSF4	1.41e-04	166	133	5	548d0d6c0ffd564036ddba78620734220ebb73d7
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNTL6 C15orf62 TRO ZFP92 HSF4	1.41e-04	166	133	5	80e164a89d22098cabe4a99a78283ba69ea0561e
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|368C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 DENND2A EDNRB TLL1 KBTBD11	1.49e-04	168	133	5	a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 DENND2A EDNRB TLL1 KBTBD11	1.49e-04	168	133	5	dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC SMO LTBP2 FLRT2 TMEM200C	1.58e-04	170	133	5	7653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB4 NPR1 ARHGEF15 TGFBR2 EXOC3L1	1.62e-04	171	133	5	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NPR1 TRIOBP IGDCC3 KLF2 EXOC3L1	1.62e-04	171	133	5	3112d15f2a28cf4a71992db4971d960716dc1264
Drug	Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A	ZSWIM8 MYO9B GNB1L OBSL1 EVPL KDM6B ZNF783 CFD WIZ MAPKBP1	2.28e-07	195	133	10	1700_DN
Drug	Pempidine tartrate [546-48-5]; Up 200; 13uM; PC3; HT_HG-U133A	ZSWIM8 EVPL ARHGEF17 BAZ2A KCNS1 SMO FLRT2 MMP11 PBXIP1	2.34e-06	196	133	9	4307_UP
Drug	Sulfameter [651-06-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A	ZHX3 EVPL ABCA7 MBD3 ZNF783 TAOK2 BAZ2A KBTBD11 KCNS1	2.66e-06	199	133	9	6212_UP
Drug	Pyrilamine maleate [59-33-6]; Down 200; 10uM; MCF7; HT_HG-U133A	MYO9B KLF2 TAOK2 MZF1 KBTBD11 KCNS1 CHPF PBXIP1	1.90e-05	194	133	8	3184_DN
Drug	Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; HL60; HG-U133A	ABCA7 WIZ BAZ2A FLRT2 MAPKBP1 MMP11 MAN1B1 EPHA1	1.97e-05	195	133	8	1410_UP
Drug	rapamycin; Down 200; 0.1uM; HL60; HG-U133A	EPRS1 DENND2A MYO9B APC2 ZNF783 WIZ MZF1 MAN1B1	2.12e-05	197	133	8	362_DN
Drug	Etodolac [41340-25-4]; Up 200; 14uM; HL60; HG-U133A	ZSWIM8 GNB1L FJX1 RHOT2 ZNF783 BAZ2A MZF1 XPNPEP3	2.20e-05	198	133	8	1407_UP
Drug	rapamycin, Streptomyces hygroscepicus; Up 200; 0.1uM; PC3; HT_HG-U133A	RHOT2 KLF2 TGFBR2 MEGF8 KCNS1 MMP11 PBXIP1	1.21e-04	188	133	7	5980_UP
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A	EPHB4 ZHX3 ZSWIM8 MYO9B EVPL MBD3 CFD	1.25e-04	189	133	7	5208_DN
Drug	Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; PC3; HT_HG-U133A	DENND2A EPM2A USP19 ZNF16 GTF2I TENM3 XPNPEP3	1.38e-04	192	133	7	6659_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	LRRK1 KDM6B MBD3 ZNF783 WIZ IFRD2 MAN1B1	1.43e-04	193	133	7	2904_DN
Drug	Fluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; MCF7; HT_HG-U133A	MLNR KLF2 TAOK2 BAZ2A LTBP2 FLRT2 PBXIP1	1.43e-04	193	133	7	3370_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	GNB1L MBD3 TAOK2 TGFBR2 GTF2I BAZ2A IFRD2	1.47e-04	194	133	7	2474_DN
Drug	Imidurea [39236-46-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A	EPHB4 ZHX3 MYO9B LRFN3 GNB1L MZF1 KBTBD11	1.47e-04	194	133	7	3522_DN
Drug	triphenyl phosphite	TSPOAP1 CFD TPP1	1.49e-04	18	133	3	CID000007540
Drug	Pipenzolate bromide [125-51-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A	ZHX3 MYO9B KLF2 TAOK2 ZNF16 WIZ PLAGL2	1.52e-04	195	133	7	6821_DN
Drug	Isradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A	MYO9B KLF2 CFD WIZ MZF1 TPP1 PBXIP1	1.52e-04	195	133	7	5447_DN
Drug	troglitazone; Down 200; 10uM; HL60; HT_HG-U133A	MYO9B ABCA7 TAOK2 TGFBR2 MEGF8 KCNS1 MAPKBP1	1.52e-04	195	133	7	6191_DN
Drug	Nabumetone [42924-53-8]; Down 200; 17.6uM; HL60; HT_HG-U133A	TSPOAP1 WDR33 GNB1L LRRK1 ABCA7 MBD3 KCNS1	1.52e-04	195	133	7	3108_DN
Drug	Melatonin [73-31-4]; Up 200; 17.2uM; PC3; HT_HG-U133A	RHOT2 USP19 TAOK2 PHF1 GTF2I WIZ KIFC3	1.52e-04	195	133	7	6293_UP
Drug	Quinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	EPHB4 ZHX3 TAOK2 WIZ MZF1 KBTBD11 EPHA1	1.52e-04	195	133	7	3191_DN
Drug	Spaglumic acid [4910-46-7]; Down 200; 13.2uM; HL60; HT_HG-U133A	EPHB4 TRIOBP KDM6B KLF2 TPP1 MAPKBP1 PBXIP1	1.52e-04	195	133	7	2962_DN
Drug	Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; MCF7; HT_HG-U133A	MYO9B EVPL TAOK2 TGFBR2 CFD LTBP2 MAPKBP1	1.57e-04	196	133	7	6846_DN
Drug	Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; HL60; HG-U133A	ZHX3 ZNF783 BAZ2A MZF1 XPNPEP3 CHPF EPHA1	1.57e-04	196	133	7	1440_UP
Drug	Clebopride maleate [84370-95-6]; Up 200; 8.2uM; PC3; HT_HG-U133A	LRRK1 KDM6B ABCA7 CELSR1 GTF2I KIFC3 PBXIP1	1.62e-04	197	133	7	6311_UP
Drug	Glycopyrrolate [596-51-0]; Down 200; 10uM; PC3; HT_HG-U133A	DENND2A WDR33 KDM6B WIZ XPNPEP3 TMEM132A PBXIP1	1.62e-04	197	133	7	7386_DN
Drug	Naringin hydrate [11032-30-7]; Down 200; 6.6uM; MCF7; HT_HG-U133A	ZHX3 ADAM19 WDR33 GNB1L CFD MZF1 PBXIP1	1.62e-04	197	133	7	5666_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A	DENND2A ZNF16 WIZ XPNPEP3 KBTBD11 CHPF ESPL1	1.62e-04	197	133	7	1224_DN
Drug	Methiazole; Down 200; 15uM; MCF7; HT_HG-U133A	ZSWIM8 LRFN3 EVPL RHOT2 DNPH1 TAOK2 MZF1	1.62e-04	197	133	7	4354_DN
Drug	Tenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A	MYO9B RYR1 TAOK2 WIZ BAZ2A KCNS1 LTBP2	1.62e-04	197	133	7	2860_UP
Drug	Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A	SAV1 ABCA7 ZNF16 TENM3 BAZ2A KBTBD11 LTBP2	1.62e-04	197	133	7	2657_UP
Drug	Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; HL60; HT_HG-U133A	ABCA7 EDNRB TAOK2 PHF1 BAZ2A KIFC3 MMP11	1.62e-04	197	133	7	2934_UP
Drug	Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A	ZSWIM8 OBSL1 EVPL ARHGEF17 ZNF783 WIZ LTBP2	1.62e-04	197	133	7	3209_UP
Drug	Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; HL60; HG-U133A	ZSWIM8 FJX1 ZNF783 BAZ2A XPNPEP3 MAPKBP1 PBXIP1	1.67e-04	198	133	7	1431_UP
Drug	nocodazole; Down 200; 1uM; MCF7; HG-U133A	OBSL1 KDM6B ARHGEF17 TAOK2 BAZ2A KCNS1 EIF3A	1.67e-04	198	133	7	621_DN
Drug	Novobiocin sodium salt [1476-53-5]; Down 200; 6.4uM; PC3; HT_HG-U133A	TGFBR2 GTF2I MEGF8 BAZ2A MZF1 TPP1 PBXIP1	1.67e-04	198	133	7	4569_DN
Drug	Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	ZHX3 EPM2A LRFN3 TAOK2 BAZ2A KBTBD11 KCNS1	1.67e-04	198	133	7	3175_DN
Drug	Isometheptene mucate; Down 200; 8.2uM; MCF7; HT_HG-U133A	SAV1 ABCA7 GTF2I WIZ KCNS1 LTBP2 PBXIP1	1.67e-04	198	133	7	6524_DN
Drug	Ethamivan [304-84-7]; Down 200; 18uM; MCF7; HT_HG-U133A	EPM2A ABCA7 RYR1 TAOK2 CFD TENM3 KBTBD11	1.67e-04	198	133	7	2879_DN
Drug	Milrinone [78415-72-2]; Down 200; 19uM; MCF7; HT_HG-U133A	EPM2A MYO9B LRFN3 TRIOBP WIZ MZF1 MAPKBP1	1.67e-04	198	133	7	7210_DN
Drug	Zoxazolamine [61-80-3]; Up 200; 23.8uM; MCF7; HT_HG-U133A	TSPOAP1 APC2 ABCA7 MBD3 WIZ BAZ2A KCNS1	1.67e-04	198	133	7	5390_UP
Drug	Dicumarol [66-76-2]; Up 200; 11.8uM; PC3; HT_HG-U133A	ZSWIM8 NPR1 RYR1 WIZ MEGF8 PNMA8A MMP11	1.67e-04	198	133	7	3766_UP
Drug	Amiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; PC3; HG-U133A	ZHX3 MYO9B LRRK1 MBD3 WIZ MZF1 KCNJ14	1.67e-04	198	133	7	1890_UP
Drug	Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; HL60; HG-U133A	EPHB4 ZHX3 MYO9B OBSL1 BAZ2A MZF1 KCNS1	1.67e-04	198	133	7	1985_UP
Drug	Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A	ZHX3 APC2 ABCA7 ZNF783 WIZ LTBP2 EPHA1	1.72e-04	199	133	7	4962_UP
Drug	Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A	ADAM19 GNB1L KDM6B ARHGEF17 TAOK2 CFD ZNF16	1.72e-04	199	133	7	3574_DN
Drug	Bupivacaine hydrochloride [18010-40-7]; Down 200; 12.4uM; HL60; HT_HG-U133A	EPM2A TAOK2 PHF1 MEGF8 LTBP2 FLRT2 MAN1B1	1.72e-04	199	133	7	2404_DN
Drug	Ciprofibrate [52214-84-3]; Down 200; 13.8uM; PC3; HT_HG-U133A	EPHB4 LRRK1 ZNF783 PHF1 GTF2I BAZ2A MZF1	1.72e-04	199	133	7	5740_DN
Drug	Dioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A	DENND2A EPM2A TRO ARHGEF17 ABCA7 KCNS1 MMP11	1.72e-04	199	133	7	6478_UP
Drug	Avermectin B1 [71751-41-2]; Up 200; 4.8uM; PC3; HT_HG-U133A	RHOT2 MBD3 RYR1 TPP1 TMEM132A KCNS1 MAN1B1	1.72e-04	199	133	7	5864_UP
Drug	Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	EPHB4 APC2 ZNF783 WIZ BAZ2A KCNS1 PBXIP1	1.72e-04	199	133	7	3220_UP
Drug	5-aza-2′-deoxycytidine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ZHX3 MYO9B TAOK2 WIZ XPNPEP3 PLAGL2 EPHA1	1.72e-04	199	133	7	920_DN
Drug	0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A	DENND2A TRO APC2 TGFBR2 FLRT2 KIFC3 PBXIP1	1.72e-04	199	133	7	3633_UP
Drug	Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	ZHX3 ZSWIM8 ADAM19 SAV1 USP19 KLF2 EPHA1	1.72e-04	199	133	7	3203_DN
Drug	Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A	KDM6B ARHGEF17 ZNF783 USP19 EDNRB BAZ2A EPHA1	1.78e-04	200	133	7	4975_UP
Drug	Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; PC3; HT_HG-U133A	NPR1 OBSL1 EDNRB TAOK2 TPP1 PNMA8A PBXIP1	1.78e-04	200	133	7	4091_UP
Drug	Saquinavir mesylate [149845-06-7]; Up 200; 5.2uM; MCF7; HT_HG-U133A	TSPOAP1 WDR33 MLNR OBSL1 LRRK1 BAZ2A PNMA8A	1.78e-04	200	133	7	3549_UP
Drug	Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A	EPHB4 ZHX3 GNB1L USP19 CFD WIZ PBXIP1	1.78e-04	200	133	7	5012_DN
Disease	Brain Tumor, Primary	FJX1 TGFBR2 SMO	3.69e-04	33	125	3	C0750974
Disease	Primary malignant neoplasm of brain	FJX1 TGFBR2 SMO	3.69e-04	33	125	3	C0750979
Disease	Recurrent Brain Neoplasm	FJX1 TGFBR2 SMO	3.69e-04	33	125	3	C0750977
Disease	Neoplasms, Intracranial	FJX1 TGFBR2 SMO	3.69e-04	33	125	3	C1527390
Disease	Benign neoplasm of brain, unspecified	FJX1 TGFBR2 SMO	3.69e-04	33	125	3	C0496899
Disease	tumor necrosis factor receptor superfamily member 19L measurement	ARHGEF17 CFD	4.90e-04	8	125	2	EFO_0008309
Disease	Malignant neoplasm of brain	FJX1 TGFBR2 SMO	5.62e-04	38	125	3	C0153633
Disease	Brain Neoplasms	FJX1 TGFBR2 SMO	6.07e-04	39	125	3	C0006118
Disease	Gastric Adenocarcinoma	EPHB4 TGFBR2 EPHA10	9.25e-04	45	125	3	C0278701
Disease	Marfan Syndrome	TGFBR2 LTBP2	9.55e-04	11	125	2	C0024796
Disease	Gastrointestinal Stromal Sarcoma	BOC TGFBR2 SMO	1.05e-03	47	125	3	C3179349
Disease	Gastrointestinal Stromal Tumors	BOC TGFBR2 SMO	1.26e-03	50	125	3	C0238198
Disease	kidney disease (biomarker_via_orthology)	XYLT1 TGFBR2	3.55e-03	21	125	2	DOID:557 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TPSGEWDIVALPGRR	CHRNB4	196	P30926
WEPPRPGGERESTQR	CCDC185	16	Q8N715
TGRTTPLGQVPRDWR	EXOC3L1	231	Q86VI1
RWEPPADTGGRQDVR	EPHA1	351	P21709
GIRVPGIFRWPSVLE	ARSH	356	Q5FYA8
VLWGREGRPGTPVDD	CXorf49;	76	A8MYA2
VPGRSESWERGEPGR	DNPH1	6	O43598
RPRAAREPGWTRGSE	ADAM19	21	Q9H013
RLAWEEIDTPGGVGR	DNM1P46	166	Q6ZS02
EDITWRGRGREGLAP	BAZ2A	1561	Q9UIF9
AWLGRARPPPAVAER	BTBD17	236	A6NE02
LSRIWGEERGFPPDR	EDNRB	21	P24530
TTRPGLELRWVPVGG	ARHGEF15	216	O94989
LRAAAWEPRVPGGTR	CELSR1	26	Q9NYQ6
WEPRVPGGTRAFALR	CELSR1	31	Q9NYQ6
RLRGDWSDTGPRARP	DCAF6	311	Q58WW2
PAPRRPWERGDGQDV	NPR1	286	P16066
ETRPVLGWIPRAGVT	C7orf31	521	Q8N865
SVIPPRTELRRGDWK	PIK3AP1	701	Q6ZUJ8
WDGRERVTPPISERI	FLRT2	411	O43155
PTAGVDPASRRGIWE	ABCA7	966	Q8IZY2
RLPAWEKGEPERRGR	TSPOAP1	1551	O95153
RPGGAEAAPSRRWLE	KCNG3	141	Q8TAE7
TSPRAPREEGLREWG	ARHGEF17	331	Q96PE2
LGPAVRPLPWQRVDR	CFD	126	P00746
RPLPWQRVDRDVAPG	CFD	131	P00746
VRWVRGGQPLPHDSR	OBSL1	1481	O75147
ETTGRWELGGRPLRP	OBSL1	1746	O75147
TIPREFPGRGGVWRV	PNMA8A	81	Q86V59
LVVGSRPELGRWEPR	EPM2A	21	O95278
RWEPRGAVRLRPAGT	EPM2A	31	O95278
VEEVRIRPAVGWGRR	LOXL3	166	P58215
GWGRRPLPVTEGLVE	LOXL3	176	P58215
PRWTLAVPGRGSDEV	GNB1L	126	Q9BYB4
RPIVSWSRLDGRPIG	IGDCC3	266	Q8IVU1
ALPQRWESREGGHRP	JSRP1	276	Q96MG2
PGPRDLVEPWVVVRG	EPHB4	381	P54760
AWDTRAVAGRERPPR	GPANK1	311	O95872
LPQGWEREEVPRRSG	MBD3	11	O95983
RRPLPGGDEAITAIW	NUDT22	31	Q9BRQ3
RDLIWVPRRGGDVIV	LRRK1	1916	Q38SD2
IPGPRVADGAWHRVR	CRB2	946	Q5IJ48
AIRWFRGEEPVSPGE	HMCN2	2391	Q8NDA2
GPWARERRAGEEPVP	KDM6B	876	O15054
LALVRPRAVGWAPVR	PCSK4	16	Q6UW60
VLPPDVGPRVDWARV	EVPL	141	Q92817
PAEPRVREVWPRGLI	MEGF8	2561	Q7Z7M0
PRLGASEAGDWLRRP	POU5F2	81	Q8N7G0
FPGPDTGIRWRRSDE	KCNS1	36	Q96KK3
GDPEPRVRWVSPQGR	LRFN3	321	Q9BTN0
VPSLAEGRPWRAALR	MROH6	161	A6NGR9
SRRWRPERIPGGTDS	TEPSIN	441	Q96N21
RLRWLPPADSGGRSD	EPHA10	356	Q5JZY3
RVVSEGWRRPALPGE	POM121L12	91	Q8N7R1
GPIRAPEHLRATVRW	RNF113A	181	O15541
PRGEVPTLRQLWSRG	PLCXD1	181	Q9NUJ7
GRLPLARSGPVWRSE	CRACDL	596	Q6NV74
LAPSVPEAPRGRERW	MAST1	1466	Q9Y2H9
PEAPRGRERWVLEVV	MAST1	1471	Q9Y2H9
RPEGDPQRTVISWRG	MAN1B1	196	Q9UKM7
WAPAPVQSPVGRRRG	KCNJ14	36	Q9UNX9
APWRSEDGRLRPLRD	FJX1	256	Q86VR8
QVPRSLWGRPGRESL	FAM189B	611	P81408
RARRIPEPELWLAVG	FCSK	751	Q8N0W3
APGTTWRRIRDEDVP	APC2	2141	O95996
SEAGWRGVVGEVPRP	ESPL1	1971	Q14674
LVWRPRHEGSGRAPI	BOC	491	Q9BWV1
SFPVSPERGRLRGWL	DACT3	6	Q96B18
PEREVDPSWGRGREP	DENND2A	131	Q9ULE3
DRIPRRGAEDDRGPW	EIF3A	1126	Q14152
WRASRGGTPREVVVE	COL20A1	411	Q9P218
DAARVFWEGAPRPVR	COL20A1	571	Q9P218
FWEGAPRPVRLVRVT	COL20A1	576	Q9P218
TESTEGRRLWPGPRE	LINC02902	6	Q6ZTY9
PRIVGGTASVRGEWP	F11	386	P03951
RPEEGGARAALSWPR	C20orf144	106	Q9BQM9
ERAQPGWGSPRRPTE	LTBP2	86	Q14767
GWGSPRRPTEAEARR	LTBP2	91	Q14767
VPALRGDDGRWRPED	HSF4	121	Q9ULV5
PSRRPVWQGGAPRED	IFRD2	6	Q12894
PRRRGRWVQPGVELS	MAPKBP1	851	O60336
RRPEIVVATPGRLWE	DDX24	436	Q9GZR7
PPRSIRGDQIAWVEG	EGLN2	231	Q96KS0
GSRVWERGGVPPRDL	CSDC2	31	Q9Y534
AAARGTTPQERRPGW	GRIP2	806	Q9C0E4
VQRVALEGRPGHRPW	GRIP2	901	Q9C0E4
PTWFGIPRLERIVRG	GTF2I	621	P78347
AVRETWGSPAPGIRL	B3GNT8	166	Q7Z7M8
GRPWRQREGEAEAVG	SBK2	326	P0C263
VGWARPELRPDVELG	RYR1	1101	P21817
RRRLLDGPRGWDASP	PRRT3	621	Q5FWE3
LRDVGPDGRSIPWGR	NLRP6	41	P59044
PDGRSIPWGRLERAD	NLRP6	46	P59044
GRELWSSRRPLRGPA	MLNR	271	O43193
GAFPTIVEREPWDGR	PDIA6	401	Q15084
IVEREPWDGRDGELP	PDIA6	406	Q15084
GPRPRLWEGQDVLAR	PHF1	26	O43189
PDGRWVLRSEPHGRF	FSCN2	96	O14926
LQPLWTGGPGERREV	KCTD11	176	Q693B1
PVPRRATDWRGVPSE	MMP11	421	P24347
GWREDIRPGEPLHTR	GALNTL6	501	Q49A17
GWGVFPEVSRAARRP	IER5	161	Q5VY09
LVDGWDDPRFPTVRG	EPRS1	446	P07814
AVWPVLRERAGAPGA	SPATA5L1	111	Q9BVQ7
PRAATSRTERIWPGG	TLL1	146	O43897
LEQVRGWRVPGPAEG	TMEM132A	506	Q24JP5
WQRPPGERGSQEIPR	TMEM200C	401	A6NKL6
WGPELPRTVRTEAGR	RHOT2	341	Q8IXI1
RVPSEAPGAGVERRW	MMP23B	6	O75900
LRGLWRVGRAPEPEP	KIFC3	16	Q9BVG8
LELGAPVASRSWRPR	SHROOM3	946	Q8TF72
RGDETPREPSSWGAR	SHROOM3	1201	Q8TF72
VLRDRGRPEIPSFWL	TGFBR2	491	P37173
ASWGLLRGERPTRIP	TAOK2	1181	Q9UL54
GWVPVREGLFAEPER	WHAMM	11	Q8TF30
STVHPQGLGERRRPW	WIZ	551	O95785
RWKRPAFTEGRREPG	OR8S1	316	Q8NH09
RADRWAPVAPLPRGA	KBTBD11	431	O94819
LRAPGEGVWARVPSL	TRIOBP	1566	Q9H2D6
VGWKLVPRPRGREAE	PLAGL2	21	Q9UPG8
GGEPAWDSPLRRVLA	RIOX1	176	Q9H6W3
AELERRFPGARVPWL	CHPF	571	Q8IZ52
GRRLPLWGDEQPRAT	C15orf62	61	A8K5M9
RGREGLRPPWSELDV	NKAPL	46	Q5M9Q1
LEREGLPPGWERVES	SAV1	231	Q9H4B6
LERGEGPWVADIPRT	ZFP92	66	A6NM28
EGDTGLPRVWAAPDR	USP19	921	O94966
WRLGDRRIPEGIAVD	XYLT1	476	Q86Y38
LRGPEIRDWRGPQLE	ZSWIM9	551	Q86XI8
SRGDGKLVVIWPPRR	MISP3	191	Q96FF7
REPAGRWKEGRPRVE	PBXIP1	511	Q96AQ6
WDQRRRGTEGFERPP	SPEM2	311	Q0P670
WGRRPAPPRDVAILQ	TRO	431	Q12816
LPEWEPRIREAFRTG	SOGA1	541	O94964
TRIIRDGGPWEDPVL	ZNF654	156	Q8IZM8
GRRAIQEIPPGIFWR	TENM3	391	Q9P273
GPERWPRREHVVTVS	IGSF9	1061	Q9P2J2
RGPCAIVERERGWPD	SMO	151	Q99835
DRRAVPSRGWDHPVR	ZFYVE1	751	Q9HBF4
LRPLRGREPEGVWNL	ZSWIM8	336	A7E2V4
RDPSRELWDGPRSGT	XPNPEP3	156	Q9NQH7
RDWGVPEGRRLPQSL	ZNF16	116	P17020
AWEGRRPGDERFPRD	WDR33	1076	Q9C0J8
GEAGDPRRLLERPWR	nan	61	Q8N1Y9
NPDIPEWRRDIGRVI	SORCS1	991	Q8WY21
TGLPRPEVVRWFGDS	ZHX3	801	Q9H4I2
PPRRIRVDLDWERGR	RNF39	361	Q9H2S5
IRWLPEEPEGRRSVA	ZNF783	406	Q6ZMS7
DQRRTLPPGWVSLGR	TPP1	26	O14773
RGLQERWPRAEPESG	KLF2	21	Q9Y5W3
PRWAPGAREAAAPVR	MYO9B	2081	Q13459
VGPALITTRWRSPRG	MZF1	326	P28698