Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP2 VLDLR LRP1B

4.07e-0916264GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP2 VLDLR LRP1B

1.33e-0821264GO:0030228
GeneOntologyMolecularFunctioncalcium ion binding

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 COMP LRP1B

1.60e-087492610GO:0005509
GeneOntologyMolecularFunctionapolipoprotein binding

LRP1 LRP4 VLDLR

2.20e-0620263GO:0034185
GeneOntologyMolecularFunctionsulfur compound binding

LRP1 THBS1 THBS2 THBS3 THBS4 COMP

3.00e-06323266GO:1901681
GeneOntologyMolecularFunctionextracellular matrix structural constituent

THBS1 THBS2 THBS3 THBS4 COMP

3.93e-06188265GO:0005201
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 LRP2 VLDLR LRP1B

4.26e-0685264GO:0038024
GeneOntologyMolecularFunctionheparin binding

THBS1 THBS2 THBS3 THBS4 COMP

4.36e-06192265GO:0008201
GeneOntologyMolecularFunctionfibronectin binding

THBS1 THBS4 COMP

1.60e-0538263GO:0001968
GeneOntologyMolecularFunctionglycosaminoglycan binding

THBS1 THBS2 THBS3 THBS4 COMP

2.19e-05268265GO:0005539
GeneOntologyMolecularFunctionproteoglycan binding

LRP1 THBS1 COMP

3.92e-0551263GO:0043394
GeneOntologyMolecularFunctioncollagen binding

THBS1 THBS4 COMP

1.56e-0481263GO:0005518
GeneOntologyMolecularFunctionhormone binding

LRP2 RXFP1 RXFP2

3.18e-04103263GO:0042562
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

LRP1 COMP

6.48e-0429262GO:0043395
GeneOntologyMolecularFunctionstructural molecule activity

TPR THBS1 THBS2 THBS3 THBS4 COMP

8.29e-04891266GO:0005198
GeneOntologyMolecularFunctionlaminin binding

THBS1 THBS4

8.91e-0434262GO:0043236
GeneOntologyMolecularFunctionlipoprotein particle binding

VLDLR THBS1

9.45e-0435262GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

VLDLR THBS1

9.45e-0435262GO:0071814
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP1 LRP2

1.17e-0339262GO:0070325
GeneOntologyMolecularFunctionintegrin binding

THBS1 THBS4 COMP

1.48e-03175263GO:0005178
GeneOntologyMolecularFunctionprotease binding

LRP1 THBS1 COMP

1.63e-03181263GO:0002020
GeneOntologyMolecularFunctionribonucleoprotein complex binding

PES1 HNRNPCL3 DHX9

2.36e-03206263GO:0043021
GeneOntologyMolecularFunctioncoreceptor activity

LRP1 LRP4

3.94e-0372262GO:0015026
GeneOntologyMolecularFunctionextracellular matrix binding

THBS1 THBS4

4.05e-0373262GO:0050840
GeneOntologyMolecularFunctionsingle-stranded RNA binding

HNRNPCL3 DHX9

9.12e-03111262GO:0003727
GeneOntologyBiologicalProcessgrowth plate cartilage development

THBS1 THBS3 COMP

5.63e-0629253GO:0003417
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

LRP1 LRP4 TPR PIP4K2B VLDLR THBS1 THBS2 CAND1 PPM1E

6.01e-061189259GO:0044087
GeneOntologyBiologicalProcessendochondral bone growth

THBS1 THBS3 COMP

1.40e-0539253GO:0003416
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

1.41e-055252GO:0061642
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

1.41e-055252GO:1905167
GeneOntologyBiologicalProcessamyloid-beta clearance

LRP1 LRP2 LRP4

1.51e-0540253GO:0097242
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

LRP1 LRP2 LRP4 TPR PIP4K2B VLDLR THBS2 CAND1 PPM1E

1.85e-051366259GO:0051130
GeneOntologyBiologicalProcessbone growth

THBS1 THBS3 COMP

2.16e-0545253GO:0098868
GeneOntologyBiologicalProcesscartilage development involved in endochondral bone morphogenesis

THBS1 THBS3 COMP

2.46e-0547253GO:0060351
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LRP2

2.95e-057252GO:1904352
GeneOntologyBiologicalProcessregulation of cell junction assembly

LRP1 LRP4 VLDLR THBS1 THBS2

3.03e-05309255GO:1901888
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

LRP1 LRP4

3.93e-058252GO:0150094
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LRP2

9.24e-0512252GO:1905165
GeneOntologyBiologicalProcessendochondral bone morphogenesis

THBS1 THBS3 COMP

1.17e-0479253GO:0060350
GeneOntologyBiologicalProcesscellular response to heat

TPR THBS1 DHX9

1.26e-0481253GO:0034605
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP1 LRP2

1.27e-0414252GO:1904350
GeneOntologyBiologicalProcessartery morphogenesis

LRP1 LRP2 COMP

1.84e-0492253GO:0048844
GeneOntologyBiologicalProcessnegative regulation of focal adhesion assembly

LRP1 THBS1

1.90e-0417252GO:0051895
GeneOntologyBiologicalProcessregulation of RNA export from nucleus

TPR DHX9

1.90e-0417252GO:0046831
GeneOntologyBiologicalProcessnegative regulation of cell-substrate junction organization

LRP1 THBS1

1.90e-0417252GO:0150118
GeneOntologyBiologicalProcessregulation of nucleobase-containing compound transport

TPR DHX9

2.64e-0420252GO:0032239
GeneOntologyBiologicalProcessendocytosis

LRP1 LRP2 LRP4 VLDLR THBS1 LRP1B

3.75e-04827256GO:0006897
GeneOntologyBiologicalProcesslysosomal protein catabolic process

LRP1 LRP2

3.83e-0424252GO:1905146
GeneOntologyBiologicalProcesstranscytosis

LRP1 LRP2

3.83e-0424252GO:0045056
GeneOntologyBiologicalProcessresponse to heat

TPR THBS1 DHX9

4.12e-04121253GO:0009408
GeneOntologyBiologicalProcessbone morphogenesis

THBS1 THBS3 COMP

4.43e-04124253GO:0060349
GeneOntologyBiologicalProcessossification

LRP4 THBS3 COMP DHX9 CD276

4.99e-04562255GO:0001503
GeneOntologyBiologicalProcessgrowth

LRP1 LRP4 THBS1 THBS3 SAFB COMP TSPYL2

5.02e-041235257GO:0040007
GeneOntologyBiologicalProcesslipoprotein transport

LRP1 LRP2

5.23e-0428252GO:0042953
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

LRP1 LRP2

5.23e-0428252GO:0007039
GeneOntologyBiologicalProcesscell junction assembly

LRP1 LRP4 VLDLR THBS1 THBS2

5.28e-04569255GO:0034329
GeneOntologyBiologicalProcessartery development

LRP1 LRP2 COMP

5.43e-04133253GO:0060840
GeneOntologyBiologicalProcesslipoprotein localization

LRP1 LRP2

5.61e-0429252GO:0044872
GeneOntologyBiologicalProcesspositive regulation of cellular component biogenesis

TPR PIP4K2B THBS2 CAND1 PPM1E

5.85e-04582255GO:0044089
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

LRP1 LRP2 VLDLR LRP1B

6.75e-04337254GO:0006898
GeneOntologyBiologicalProcessbehavioral response to pain

THBS1 THBS4

6.84e-0432252GO:0048266
GeneOntologyBiologicalProcessconnective tissue development

THBS1 THBS3 RXFP1 COMP

7.21e-04343254GO:0061448
GeneOntologyBiologicalProcessregulation of ossification

LRP4 COMP CD276

7.27e-04147253GO:0030278
GeneOntologyBiologicalProcessresponse to unfolded protein

THBS1 THBS4 COMP

7.42e-04148253GO:0006986
GeneOntologyBiologicalProcessactivation of adenylate cyclase activity

RXFP1 RXFP2

7.73e-0434252GO:0007190
GeneOntologyBiologicalProcessresponse to topologically incorrect protein

THBS1 THBS4 COMP

1.03e-03166253GO:0035966
GeneOntologyBiologicalProcesspositive regulation of adenylate cyclase activity

RXFP1 RXFP2

1.07e-0340252GO:0045762
GeneOntologyBiologicalProcessnegative regulation of cell junction assembly

LRP1 THBS1

1.12e-0341252GO:1901889
GeneOntologyBiologicalProcessnegative regulation of cell-matrix adhesion

LRP1 THBS1

1.24e-0343252GO:0001953
GeneOntologyBiologicalProcessresponse to hormone

LRP2 PIP4K2B THBS1 SAFB RXFP1 RXFP2

1.27e-031042256GO:0009725
GeneOntologyBiologicalProcesspositive regulation of protein metabolic process

LRP1 LRP2 LRP4 VLDLR THBS1 THBS4 DHX9

1.35e-031458257GO:0051247
GeneOntologyBiologicalProcessimport into cell

LRP1 LRP2 LRP4 VLDLR THBS1 LRP1B

1.48e-031074256GO:0098657
GeneOntologyBiologicalProcesspositive regulation of cyclase activity

RXFP1 RXFP2

1.54e-0348252GO:0031281
GeneOntologyBiologicalProcessapoptotic cell clearance

LRP1 THBS1

1.54e-0348252GO:0043277
GeneOntologyBiologicalProcesspositive regulation of lyase activity

RXFP1 RXFP2

1.60e-0349252GO:0051349
GeneOntologyBiologicalProcessresponse to pain

THBS1 THBS4

1.73e-0351252GO:0048265
GeneOntologyBiologicalProcessregulation of synapse assembly

LRP4 VLDLR THBS2

1.82e-03202253GO:0051963
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

LRP1 LRP2 THBS1 COMP

1.89e-03445254GO:0141091
GeneOntologyBiologicalProcessregulation of protein phosphorylation

LRP4 VLDLR THBS1 THBS4 PPM1E TSPYL2

1.95e-031133256GO:0001932
GeneOntologyBiologicalProcessresponse to temperature stimulus

TPR THBS1 DHX9

1.97e-03208253GO:0009266
GeneOntologyCellularComponentclathrin-coated pit

LRP1 LRP2 VLDLR

1.32e-0480263GO:0005905
GeneOntologyCellularComponentcell surface

LRP1 LRP2 LRP4 CORIN VLDLR THBS1 CD276

3.17e-041111267GO:0009986
GeneOntologyCellularComponentcollagen-containing extracellular matrix

THBS1 THBS2 THBS3 THBS4 COMP

4.35e-04530265GO:0062023
GeneOntologyCellularComponentextracellular matrix

THBS1 THBS2 THBS3 THBS4 COMP

1.14e-03656265GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

THBS1 THBS2 THBS3 THBS4 COMP

1.16e-03658265GO:0030312
GeneOntologyCellularComponentaxonal growth cone

LRP1 LRP2

1.43e-0345262GO:0044295
DomainLDLR_class-A_CS

LRP1 LRP2 LRP4 CORIN VLDLR RXFP1 C8A LRP1B RXFP2

7.17e-1940259IPR023415
DomainLdl_recept_a

LRP1 LRP2 LRP4 CORIN VLDLR RXFP1 C8A LRP1B RXFP2

2.31e-1845259PF00057
Domain-

LRP1 LRP2 LRP4 CORIN VLDLR RXFP1 C8A LRP1B RXFP2

2.88e-18462594.10.400.10
DomainLDLRA_1

LRP1 LRP2 LRP4 CORIN VLDLR RXFP1 C8A LRP1B RXFP2

4.37e-1848259PS01209
DomainLDrepeatLR_classA_rpt

LRP1 LRP2 LRP4 CORIN VLDLR RXFP1 C8A LRP1B RXFP2

5.35e-1849259IPR002172
DomainLDLa

LRP1 LRP2 LRP4 CORIN VLDLR RXFP1 C8A LRP1B RXFP2

5.35e-1849259SM00192
DomainLDLRA_2

LRP1 LRP2 LRP4 CORIN VLDLR RXFP1 C8A LRP1B RXFP2

5.35e-1849259PS50068
DomainEGF_CA

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 COMP LRP1B

7.71e-18862510PF07645
DomainEGF_CA

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 COMP LRP1B

2.92e-161222510SM00179
DomainEGF-like_Ca-bd_dom

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 COMP LRP1B

3.46e-161242510IPR001881
DomainTSP3

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-155255PS51234
DomainTSP_CTER

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-155255PS51236
Domain-

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-1552554.10.1080.10
DomainThrombospondin_C

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-155255IPR008859
DomainTSP_C

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-155255PF05735
DomainThrombospondin_3_rpt

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-155255IPR017897
DomainTSP_3

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-155255PF02412
DomainThrombospondin_3-like_rpt

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-155255IPR003367
DomainTSP_type-3_rpt

THBS1 THBS2 THBS3 THBS4 COMP

2.81e-155255IPR028974
DomainEGF_3

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 C8A COMP LRP1B

3.78e-152352511PS50026
DomainEGF-like_dom

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 C8A COMP LRP1B

7.17e-152492511IPR000742
DomainEGF_1

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 C8A COMP LRP1B

9.33e-152552511PS00022
DomainEGF-like_CS

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 C8A COMP LRP1B

1.21e-142612511IPR013032
DomainEGF_2

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 C8A COMP LRP1B

1.43e-142652511PS01186
DomainEGF

LRP1 LRP2 LRP4 VLDLR THBS1 THBS2 THBS3 THBS4 COMP LRP1B

2.27e-132352510SM00181
DomainGrowth_fac_rcpt_

LRP1 LRP2 LRP4 VLDLR THBS3 THBS4 C8A COMP LRP1B

2.86e-13156259IPR009030
DomainEGF_Ca-bd_CS

LRP1 LRP2 LRP4 VLDLR THBS3 THBS4 COMP LRP1B

3.97e-1397258IPR018097
DomainEGF_CA

LRP1 LRP2 LRP4 VLDLR THBS3 THBS4 COMP LRP1B

4.69e-1399258PS01187
DomainLdl_recept_b

LRP1 LRP2 LRP4 VLDLR LRP1B

5.57e-1214255PF00058
DomainLDLRB

LRP1 LRP2 LRP4 VLDLR LRP1B

5.57e-1214255PS51120
DomainLY

LRP1 LRP2 LRP4 VLDLR LRP1B

8.35e-1215255SM00135
DomainLDLR_classB_rpt

LRP1 LRP2 LRP4 VLDLR LRP1B

8.35e-1215255IPR000033
DomainEGF

LRP1 LRP2 LRP4 VLDLR THBS2 THBS4 LRP1B

2.34e-10126257PF00008
Domain-

LRP1 LRP2 LRP4 VLDLR LRP1B

1.57e-09392552.120.10.30
DomainThbs/COMP_coiled-coil

THBS3 THBS4 COMP

2.12e-093253IPR024665
DomainCOMP

THBS3 THBS4 COMP

2.12e-093253PF11598
Domain6-blade_b-propeller_TolB-like

LRP1 LRP2 LRP4 VLDLR LRP1B

3.71e-0946255IPR011042
DomainTSPN

THBS1 THBS2 THBS3 THBS4

2.17e-0823254SM00210
DomaincEGF

LRP1 LRP2 LRP4 LRP1B

3.66e-0826254IPR026823
DomaincEGF

LRP1 LRP2 LRP4 LRP1B

3.66e-0826254PF12662
Domain-

THBS1 THBS2 THBS3 THBS4 COMP

1.50e-07952552.60.120.200
DomainASX_HYDROXYL

LRP1 LRP2 LRP4 VLDLR LRP1B

1.94e-07100255PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 LRP2 LRP4 VLDLR LRP1B

2.60e-07106255IPR000152
DomainLaminin_G

THBS1 THBS2 THBS3 THBS4

1.01e-0658254IPR001791
DomainDUF5050

LRP1 LRP1B

1.72e-062252IPR032485
DomainDUF5050

LRP1 LRP1B

1.72e-062252PF16472
DomainRelaxin_rcpt

RXFP1 RXFP2

1.72e-062252IPR008112
DomainConA-like_dom

THBS1 THBS2 THBS3 THBS4 COMP

9.29e-06219255IPR013320
DomainTSP_1

THBS1 THBS2 C8A

7.98e-0563253PF00090
DomainTSP1

THBS1 THBS2 C8A

8.76e-0565253SM00209
DomainTSP1_rpt

THBS1 THBS2 C8A

8.76e-0565253IPR000884
DomainTSP1

THBS1 THBS2 C8A

8.76e-0565253PS50092
DomainVWC

THBS1 THBS2

6.36e-0428252PF00093
DomainVWFC_1

THBS1 THBS2

1.05e-0336252PS01208
DomainVWC

THBS1 THBS2

1.17e-0338252SM00214
DomainVWFC_2

THBS1 THBS2

1.17e-0338252PS50184
DomainVWF_dom

THBS1 THBS2

1.43e-0342252IPR001007
DomainEGF_extracell

LRP2 LRP1B

2.90e-0360252IPR013111
DomainEGF_2

LRP2 LRP1B

2.90e-0360252PF07974
DomainLRRNT

RXFP1 RXFP2

7.56e-0398252IPR000372
DomainLRRNT

RXFP1 RXFP2

7.56e-0398252SM00013
PathwayKEGG_ECM_RECEPTOR_INTERACTION

THBS1 THBS2 THBS3 THBS4 COMP

3.22e-0784255M7098
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

THBS1 THBS2 THBS3 THBS4 COMP

3.63e-0786255M2642
PathwayREACTOME_SIGNALING_BY_PDGF

THBS1 THBS2 THBS3 THBS4

2.85e-0657254MM14713
PathwayREACTOME_SIGNALING_BY_PDGF

THBS1 THBS2 THBS3 THBS4

3.06e-0658254M2049
PathwayKEGG_FOCAL_ADHESION

THBS1 THBS2 THBS3 THBS4 COMP

2.25e-05199255M7253
PathwayWP_FOCAL_ADHESION

THBS1 THBS2 THBS3 THBS4 COMP

2.25e-05199255M39402
PathwayREACTOME_RELAXIN_RECEPTORS

RXFP1 RXFP2

8.40e-058252M27371
PathwayREACTOME_RELAXIN_RECEPTORS

RXFP1 RXFP2

1.35e-0410252MM15111
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

THBS1 THBS2 THBS3 THBS4 COMP

1.63e-04302255M39719
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_3

LRP1 VLDLR

2.33e-0413252M42551
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

THBS1 THBS2 THBS3 THBS4 COMP

2.33e-04326255MM15917
PathwayWP_PI3KAKT_SIGNALING

THBS1 THBS2 THBS3 THBS4 COMP

2.79e-04339255M39736
PathwayWP_FOCAL_ADHESION

THBS1 THBS2 THBS3 THBS4

3.05e-04187254MM15913
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

LRP1 LRP2 LRP4 VLDLR LRP1B

4.78e-04381255M48063
PathwayWP_COMPLEMENT_SYSTEM

LRP2 THBS1 C8A

6.31e-0496253M39581
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

THBS1 THBS3

1.27e-0330252MM15812
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

THBS1 THBS3

1.27e-0330252M39641
PathwayPID_INTEGRIN_A4B1_PATHWAY

THBS1 THBS2

1.54e-0333252M277
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THBS1 THBS2

2.15e-0339252M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

THBS1 THBS2

2.15e-0339252MM15165
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

CORIN RXFP1 RXFP2

2.46e-03154253MM15974
PathwayPID_UPA_UPAR_PATHWAY

LRP1 VLDLR

2.49e-0342252M174
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

CORIN RXFP1 RXFP2

2.56e-03156253M39475
PathwayWP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS

THBS1 THBS2

2.61e-0343252M39565
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2

2.85e-0345252MM15344
PathwayREACTOME_SUMOYLATION

TPR SAFB HNRNPCL3

3.21e-03169253MM14919
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2

3.24e-0348252M27642
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS1 THBS2 THBS3 THBS4 COMP

1.55e-16526530622267
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

THBS1 THBS2 THBS3 THBS4 COMP

8.68e-15826524460873
Pubmed

Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.

THBS1 THBS2 THBS3 THBS4

2.45e-1342646338048
Pubmed

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.

THBS1 THBS3 THBS4 COMP

1.23e-12526418467703
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP2 LRP4 VLDLR LRP1B

3.13e-122126521337463
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP2 LRP4 LRP1B

8.07e-111126424639464
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP2 VLDLR LRP1B

2.44e-101426415082773
Pubmed

Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.

THBS1 THBS2 THBS3

3.71e-1032639373030
Pubmed

Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.

VLDLR THBS1 THBS2

3.71e-10326318032585
Pubmed

Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.

THBS1 THBS2 THBS4

3.71e-10326325976449
Pubmed

mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.

THBS1 THBS2 THBS3

3.71e-10326334669362
Pubmed

Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

THBS1 THBS2 THBS3

3.71e-1032631459996
Pubmed

Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.

THBS3 THBS4 COMP

3.71e-10326333910854
Pubmed

Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.

THBS1 THBS2 THBS4

3.71e-10326318178577
Pubmed

Differential expression of thrombospondin 1, 2, and 3 during murine development.

THBS1 THBS2 THBS3

3.71e-1032638400410
Pubmed

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

THBS1 THBS2 THBS4

3.71e-10326312482844
Pubmed

Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.

THBS1 THBS2 COMP

3.71e-10326326168731
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2 THBS1

1.48e-0942637775583
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2 LRP4

3.70e-09526319047013
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

LRP1 LRP2 VLDLR

3.70e-09526318685438
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP1 LRP2 VLDLR

1.30e-08726312169628
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 LRP2 VLDLR

1.34e-071426317389516
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

LRP1 LRP2 VLDLR

3.00e-071826310827173
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

THBS1 THBS2 THBS3 THBS4 COMP

4.54e-0721026516537572
Pubmed

Induced thrombospondin expression in the mouse pancreas during pancreatic injury.

THBS1 THBS2

5.37e-07226216181801
Pubmed

Expression of thrombospondin-1 in ischemia-induced retinal neovascularization.

THBS1 THBS2

5.37e-07226210027393
Pubmed

Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations.

THBS1 THBS2

5.37e-07226217620335
Pubmed

Identification of a homozygous missense mutation in LRP2 and a hemizygous missense mutation in TSPYL2 in a family with mild intellectual disability.

LRP2 TSPYL2

5.37e-07226226529358
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

5.37e-07226215963947
Pubmed

Corneal stromal cells (keratocytes) express thrombospondins 2 and 3 in wound repair phenotype.

THBS2 THBS3

5.37e-07226211943589
Pubmed

The different ligand-binding modes of relaxin family peptide receptors RXFP1 and RXFP2.

RXFP1 RXFP2

5.37e-07226222973049
Pubmed

Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes.

THBS1 THBS2

5.37e-07226223660684
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

5.37e-07226234445520
Pubmed

Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population.

THBS2 THBS4

5.37e-07226227160021
Pubmed

Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.

LRP1 VLDLR

5.37e-07226215327526
Pubmed

Thrombospondin 3 is a developmentally regulated heparin binding protein.

THBS1 THBS3

5.37e-0722628288588
Pubmed

Expression and initial characterization of recombinant mouse thrombospondin 1 and thrombospondin 3.

THBS1 THBS3

5.37e-0722628654563
Pubmed

Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma.

THBS1 THBS2

5.37e-07226239122122
Pubmed

Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.

THBS1 THBS2

5.37e-07226234425286
Pubmed

Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.

THBS1 THBS2

5.37e-07226222930728
Pubmed

Cultured human retinal pigment epithelial cells differentially express thrombospondin-1, -2, -3, and -4.

THBS3 THBS4

5.37e-07226211137453
Pubmed

Thrombospondin 4 deficiency in mouse impairs neuronal migration in the early postnatal and adult brain.

THBS1 THBS4

5.37e-07226224983516
Pubmed

Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells.

THBS1 THBS2

5.37e-0722628126073
Pubmed

Relative abundance of thrombospondin 2 and thrombospondin 3 mRNAs in human tissues.

THBS2 THBS3

5.37e-07226210329465
Pubmed

Polymorphisms A387P in thrombospondin-4 and N700S in thrombospondin-1 perturb calcium binding sites.

THBS1 THBS4

5.37e-07226216148025
Pubmed

Contribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.

THBS1 THBS2

5.37e-07226233981184
Pubmed

Variants within the COMP and THBS2 genes are not associated with Achilles tendinopathy in a case-control study of South African and Australian populations.

THBS2 COMP

5.37e-07226223875975
Pubmed

Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.

THBS1 THBS2

5.37e-07226218594557
Pubmed

Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis.

THBS1 THBS2

5.37e-07226215037577
Pubmed

THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.

THBS1 THBS2

5.37e-07226238339060
Pubmed

The evolution of the thrombospondin gene family.

THBS1 THBS4

5.37e-0722628350346
Pubmed

COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.

THBS4 COMP

5.37e-07226230464261
Pubmed

Intermolecular interactions of thrombospondins drive their accumulation in extracellular matrix.

THBS1 COMP

5.37e-07226225995382
Pubmed

Cellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related protein.

LRP1 THBS1

5.37e-0722629045712
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Temporal Lobe Epilepsy Before and After Surgery.

THBS1 THBS2

5.37e-07226233372257
Pubmed

An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.

THBS1 THBS2

5.37e-07226221762961
Pubmed

TSP1 and TSP2 Have Unique and Overlapping Roles in Protecting against Noise-Induced Auditory Synaptopathy.

THBS1 THBS2

5.37e-07226230928339
Pubmed

Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice.

RXFP1 RXFP2

5.37e-07226222028476
Pubmed

Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).

LRP1 THBS1

5.37e-07226217154366
Pubmed

Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.

THBS1 THBS2

5.37e-0722629694593
Pubmed

Resolving the unconventional mechanisms underlying RXFP1 and RXFP2 receptor function.

RXFP1 RXFP2

5.37e-07226219416161
Pubmed

Modeling the primary hormone-binding site of RXFP1 and RXFP2.

RXFP1 RXFP2

5.37e-07226219416162
Pubmed

Splice variants of the relaxin and INSL3 receptors reveal unanticipated molecular complexity.

RXFP1 RXFP2

5.37e-07226216051677
Pubmed

Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.

THBS1 THBS4

5.37e-07226222745497
Pubmed

Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans.

LRP1 THBS1

5.37e-07226214991768
Pubmed

The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.

THBS1 THBS2

5.37e-07226212213711
Pubmed

Increased cortical expression of two synaptogenic thrombospondins in human brain evolution.

THBS2 THBS4

5.37e-07226217182969
Pubmed

Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

THBS1 THBS2

5.37e-07226217143334
Pubmed

Association of Thrombospondin-1 (N700S) and Thrombospondin-4 (A387P) Gene Polymorphisms with the Incidence of Acute Myocardial Infarction in Egyptians.

THBS1 THBS4

5.37e-07226229336258
Pubmed

Biophysical characterization of the signature domains of thrombospondin-4 and thrombospondin-2.

THBS2 THBS4

5.37e-07226216246837
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Common Brain Tumors.

THBS1 THBS2

5.37e-07226233759165
Pubmed

Thrombospondin expression in aldosterone-producing adenomas.

THBS1 THBS2

5.37e-07226212358136
Pubmed

Regulation of T-lymphocyte motility, adhesion and de-adhesion by a cell surface mechanism directed by low density lipoprotein receptor-related protein 1 and endogenous thrombospondin-1.

LRP1 THBS1

5.37e-07226224877199
Pubmed

Antigen-induced regulation of T-cell motility, interaction with antigen-presenting cells and activation through endogenous thrombospondin-1 and its receptors.

LRP1 THBS1

5.37e-07226225393517
Pubmed

A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome.

THBS1 THBS2

5.37e-0722621712771
Pubmed

Conjunctival inflammation in thrombospondin-1 deficient mouse model of Sjögren's syndrome.

THBS1 THBS4

5.37e-07226224086667
Pubmed

Characterization of novel splice variants of LGR7 and LGR8 reveals that receptor signaling is mediated by their unique low density lipoprotein class A modules.

RXFP1 RXFP2

5.37e-07226216963451
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP1 LRP2 VLDLR LRP1B

9.53e-0710126423382219
Pubmed

A novel role for relaxin-2 in the pathogenesis of primary varicosis.

RXFP1 RXFP2

1.61e-06326222737225
Pubmed

Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.

THBS1 THBS2

1.61e-06326216598380
Pubmed

Increased sensitivity to kindling in mice lacking TSP1.

THBS1 THBS2

1.61e-06326226241338
Pubmed

Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.

THBS1 THBS2

1.61e-06326227513329
Pubmed

Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.

THBS1 THBS2

1.61e-06326218787106
Pubmed

Regulation of VEGF-A, VEGFR-I, thrombospondin-1, -2, and -3 expression in a human pituitary cell line (HP75) by TGFbeta1, bFGF, and EGF.

THBS1 THBS2

1.61e-06326215347840
Pubmed

Extracellular matrix retention of thrombospondin 1 is controlled by its conserved C-terminal region.

THBS1 COMP

1.61e-06326218285447
Pubmed

The relationship among apolipoprotein(a) polymorphisms, the low-density lipoprotein receptor-related protein, and the very low density lipoprotein receptor genes, and plasma lipoprotein(A) concentration in the Czech population.

LRP1 VLDLR

1.61e-06326211931574
Pubmed

The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.

LRP1 VLDLR

1.61e-06326218277139
Pubmed

Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes.

THBS2 THBS4

1.61e-06326215121769
Pubmed

Identification of key residues essential for the structural fold and receptor selectivity within the A-chain of human gene-2 (H2) relaxin.

RXFP1 RXFP2

1.61e-06326223024363
Pubmed

Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling.

LRP1 THBS2

1.61e-06326220472562
Pubmed

The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer.

THBS1 THBS2

1.61e-06326231092423
Pubmed

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.

THBS1 THBS2

1.61e-06326219818485
Pubmed

EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.

THBS1 THBS2

1.61e-06326217638877
Pubmed

TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro.

THBS1 THBS2

1.61e-06326230939949
Pubmed

Activation of orphan receptors by the hormone relaxin.

RXFP1 RXFP2

1.61e-06326211809971
Pubmed

Thrombospondin 1 and Reelin act through Vldlr to regulate cardiac growth and repair.

VLDLR THBS1

1.61e-06326238147128
Pubmed

Structural Insights into the Unique Modes of Relaxin-Binding and Tethered-Agonist Mediated Activation of RXFP1 and RXFP2.

RXFP1 RXFP2

1.61e-06326234454945
Pubmed

Interactions between CD47 and thrombospondin reduce inflammation.

THBS1 THBS2

1.61e-06326217442977
Pubmed

Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.

RXFP1 RXFP2

1.61e-06326216411781
Pubmed

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

THBS1 THBS2

1.61e-06326219004835
InteractionZFP41 interactions

LRP1 LRP2 LRP4 SAFB LRP1B

9.51e-0957265int:ZFP41
InteractionANKRD36B interactions

LRP1 LRP2 LRP4 VLDLR LRP1B

1.24e-0860265int:ANKRD36B
InteractionTHBS1 interactions

LRP1 LRP2 THBS1 THBS2 THBS3

5.43e-07127265int:THBS1
InteractionTHBS2 interactions

THBS1 THBS2 THBS3

1.82e-0619263int:THBS2
InteractionZNF224 interactions

LRP2 LRP4 LRP1B

2.14e-0620263int:ZNF224
InteractionTHBS3 interactions

THBS1 THBS2 THBS3 THBS4

2.35e-0674264int:THBS3
InteractionIGFL3 interactions

LRP2 LRP4 VLDLR LRP1B

2.49e-0675264int:IGFL3
InteractionLRPAP1 interactions

LRP1 LRP2 LRP4 VLDLR LRP1B

3.04e-06180265int:LRPAP1
InteractionNTN5 interactions

LRP2 LRP4 LRP1B

3.79e-0624263int:NTN5
InteractionDYRK1A interactions

LRP2 LRP4 TPR VLDLR THBS1 LRP1B TSPYL2

4.66e-06552267int:DYRK1A
InteractionFEZF1 interactions

LRP2 LRP4 LRP1B

6.11e-0628263int:FEZF1
InteractionLPL interactions

LRP1 LRP2 VLDLR

1.21e-0535263int:LPL
InteractionCD36 interactions

VLDLR THBS1 CAND1

1.69e-0539263int:CD36
InteractionZNF408 interactions

LRP2 LRP4 VLDLR LRP1B

3.40e-05145264int:ZNF408
InteractionTHBS4 interactions

THBS3 THBS4

4.46e-058262int:THBS4
InteractionSERPINE1 interactions

LRP1 LRP2 LRP1B

4.53e-0554263int:SERPINE1
InteractionTRO interactions

LRP1 THBS3 PPM1E

9.44e-0569263int:TRO
InteractionZNF563 interactions

LRP4 LRP1B

1.05e-0412262int:ZNF563
InteractionAPBB1 interactions

LRP1 LRP2 THBS3 DHX9

1.08e-04195264int:APBB1
InteractionCALCR interactions

LRP1 THBS1

1.24e-0413262int:CALCR
InteractionRLN2 interactions

RXFP1 RXFP2

1.44e-0414262int:RLN2
InteractionSNX17 interactions

LRP1 LRP2 VLDLR

1.52e-0481263int:SNX17
InteractionCUBN interactions

LRP1 LRP2

1.66e-0415262int:CUBN
InteractionLRP1B interactions

LRP1 LRP2 LRP1B

1.76e-0485263int:LRP1B
InteractionMMP2 interactions

THBS1 THBS2 CAND1

1.88e-0487263int:MMP2
InteractionDEFB123 interactions

LRP4 LRP1B

1.90e-0416262int:DEFB123
InteractionSCN3A interactions

LRP1 LRP2

1.90e-0416262int:SCN3A
InteractionCLU interactions

LRP1 LRP2 VLDLR LRP1B

2.58e-04245264int:CLU
InteractionSYT1 interactions

LRP2 VLDLR LRP1B

3.27e-04105263int:SYT1
InteractionEGFL6 interactions

LRP2 LRP1B

3.31e-0421262int:EGFL6
InteractionDAB1 interactions

LRP1 LRP2 VLDLR

3.46e-04107263int:DAB1
InteractionMATN2 interactions

THBS4 COMP DHX9

4.06e-04113263int:MATN2
InteractionCNPY4 interactions

RXFP1 RXFP2

4.34e-0424262int:CNPY4
InteractionSULF2 interactions

LRP2 LRP4 LRP1B

4.73e-04119263int:SULF2
InteractionZDHHC15 interactions

LRP1 LRP2 THBS1

5.46e-04125263int:ZDHHC15
InteractionGLI4 interactions

LRP2 LRP1B TSPYL2

5.46e-04125263int:GLI4
InteractionTNFAIP6 interactions

LRP2 THBS1

5.51e-0427262int:TNFAIP6
InteractionPID1 interactions

LRP1 LRP4

5.51e-0427262int:PID1
InteractionZNF517 interactions

LRP2 LRP1B

6.36e-0429262int:ZNF517
InteractionMAP10 interactions

LRP4 TSPYL2

6.36e-0429262int:MAP10
InteractionLGALS1 interactions

LRP2 THBS1 DHX9 CD276

8.12e-04332264int:LGALS1
InteractionITGB1BP1 interactions

LRP1 LRP2

8.25e-0433262int:ITGB1BP1
InteractionANKS1B interactions

LRP1 LRP2

8.75e-0434262int:ANKS1B
InteractionBRD1 interactions

LRP1 LRP2 LRP4 TSPYL2

9.27e-04344264int:BRD1
InteractionSOST interactions

LRP2 LRP4

9.28e-0435262int:SOST
Cytoband1q25

TPR DHX9

9.94e-05262621q25
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2 LRP4 VLDLR LRP1B

1.60e-1313145634
GeneFamilyRelaxin family peptide receptors

RXFP1 RXFP2

3.34e-064142217
GeneFamilyADAM metallopeptidase domain containing|CD molecules

LRP1 CD276

3.63e-02394142471
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS1 THBS2 THBS3 THBS4 COMP

9.20e-07191255MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS1 THBS2 THBS3 THBS4 COMP

1.05e-06196255M3008
CoexpressionNABA_CORE_MATRISOME

THBS1 THBS2 THBS3 THBS4 COMP

5.02e-06270255MM17057
CoexpressionNABA_CORE_MATRISOME

THBS1 THBS2 THBS3 THBS4 COMP

5.48e-06275255M5884
CoexpressionHALLMARK_COAGULATION

LRP1 THBS1 C8A COMP

8.54e-06138254M5946
CoexpressionNABA_MATRISOME_HGSOC_OMENTAL_METASTASIS

THBS1 THBS2 COMP

2.41e-0559253M47993
CoexpressionGSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_UP

LRP1 TPR THBS3 NELFCD

3.60e-05199254M6638
CoexpressionGSE15767_MED_VS_SCS_MAC_LN_UP

LRP1 LRP4 THBS1 CD276

3.67e-05200254M3584
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

LRP1 THBS1 THBS2 COMP

3.67e-05200254M5930
CoexpressionTURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN

THBS2 THBS4 COMP

4.75e-0574253M13547
CoexpressionVERRECCHIA_RESPONSE_TO_TGFB1_C4

THBS1 THBS2

4.78e-0511252M566
CoexpressionLY_AGING_MIDDLE_UP

THBS2 COMP

7.89e-0514252M19146
CoexpressionOSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN

TPR VLDLR THBS1 SAFB

1.37e-04281254M7089
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

LRP1 LRP2 CORIN LRP1B HNRNPCL3

1.83e-04574255M39056
CoexpressionAZARE_STAT3_TARGETS

THBS1 DHX9

2.38e-0424252M2312
CoexpressionWILLIAMS_ESR1_TARGETS_UP

THBS1 PPM1E

2.80e-0426252M2970
CoexpressionNABA_MATRISOME_METASTATIC_COLORECTAL_LIVER_METASTASIS

THBS2 COMP

3.74e-0430252M47990
CoexpressionDESCARTES_FETAL_ADRENAL_STROMAL_CELLS

THBS2 RXFP1 RXFP2

4.32e-04156253M40151
CoexpressionLIEN_BREAST_CARCINOMA_METAPLASTIC

THBS1 THBS2

4.53e-0433252M11654
CoexpressionSIMBULAN_UV_RESPONSE_NORMAL_DN

PIP4K2B THBS1

4.53e-0433252M16114
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

LRP1 LRP2 VLDLR THBS1 THBS4

1.20e-04408265gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_100

CORIN THBS1 THBS2

1.56e-0486263gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

LRP1 THBS1 THBS2

1.61e-0487263GSM777050_100
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

LRP1 THBS1 THBS2 THBS3 THBS4

1.66e-04437265GSM777046_500
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

LRP1 LRP4 THBS1 PPM1E CD276

4.89e-08173265c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4 COMP

8.00e-081912651b26056df078674f37a6c06f6256b30cfcec21a7
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4 COMP

8.22e-08192265b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCellMesenchymal_cells-Arteriolar_fibro.|World / Lineage and Cell class

LRP1 THBS2 THBS3 THBS4 COMP

8.65e-08194265c1e8923a50b4138a1e4c054c0c17b7f7122aa8a9
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4 COMP

8.87e-08195265d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4 COMP

9.10e-0819626561bee32ca299219f31a30b57124e44e85b798e9f
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4 COMP

9.10e-08196265fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 THBS2 THBS4 COMP RXFP2

9.34e-0819726571786e9432e2d649f5d86f639abb25e7102deb67
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4 COMP

9.34e-08197265cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCellMesenchymal_cells-Arteriolar_fibro.|Mesenchymal_cells / Lineage and Cell class

LRP1 THBS2 THBS3 THBS4 COMP

9.34e-08197265cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS2 THBS3 THBS4 COMP

9.58e-08198265524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4 COMP

9.82e-08199265edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

LRP4 THBS1 PPM1E CD276

1.55e-0614726487c24843cb0e87ad42e725d08423131a5d2d25a3
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

LRP4 VLDLR COMP PPM1E

3.02e-06174264430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

LRP4 VLDLR THBS1 CD276

3.53e-0618126456ae86072858c156681507aecd1bc6cb0a3372d2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 COMP

3.77e-06184264c9d7ec17cc5b7ba1b1e721ca392746e8f4a3d41f
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

LRP1 LRP4 THBS1 CD276

3.77e-06184264684d05340a3dfb8aa08b881516a37f9627a10448
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

CORIN THBS1 THBS3 COMP

3.77e-061842641e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS3 THBS4

3.94e-06186264a66da8453bb78f7e9f5f59452b3c50ae679d83c3
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 THBS1 THBS2 LRP1B

3.94e-061862647582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS3

4.28e-06190264ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 VLDLR THBS2 THBS3

4.37e-061912649214655dca96d766737c9f30b624d7fe7050342e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4

4.46e-0619226411088878043a6ff95ba1970361256a82e434b80a
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4

4.56e-0619326449600db68ed65cafc67bd45a285b364e4f5f88af
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS2 THBS4

4.56e-0619326445b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellP15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CORIN THBS1 THBS2 THBS3

4.65e-061942645f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCellTracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CORIN COMP LRP1B

5.04e-0619826455f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 CORIN COMP LRP1B

5.04e-06198264c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

THBS2 THBS3 THBS4 COMP

5.04e-061982649f9dcf23ffb333105263132d87b90095642294cf
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 THBS2 THBS4 COMP

5.14e-061992641fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCellFibroblasts-CD34+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

LRP1 THBS2 THBS4 COMP

5.14e-0619926413ff7409e200a0b46cdb7924d15ef33639693622
ToppCell(2)_Fibroblasts|World / Cell class and subclass of bone marrow stroma cells in homeostatis

LRP1 THBS2 THBS4 COMP

5.14e-06199264777423b413376b0d3fbd92ff51dd0133fb54d293
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 LRP4 THBS4 LRP1B

5.14e-0619926419a97e27a4758e794ce7246d295e112b47931a48
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 THBS2 THBS4 COMP

5.14e-061992649672230aa0bc6a7289050c955f5154ca183a5159
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 THBS2 THBS4 COMP

5.14e-06199264e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 CORIN THBS2 COMP

5.14e-06199264fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 THBS2 THBS3 THBS4

5.25e-06200264747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CORIN COMP LRP1B TSPYL2

5.25e-06200264b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CORIN COMP LRP1B TSPYL2

5.25e-06200264f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 THBS2 THBS3 THBS4

5.25e-06200264de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 VLDLR THBS1

7.59e-05142263a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 VLDLR THBS1

7.59e-05142263d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellIonocyte|World / shred by cell class for nasal brushing

CORIN THBS1 THBS4

9.65e-051542636b78fb0c96fc7b5e901c39b3424f4aa8d0a6b9cf
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LRP1B RXFP2

1.08e-04160263c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

LRP4 THBS1 CD276

1.08e-04160263ab769516f9f7798d1390ef215caf22a2d3d53e63
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LRP1B RXFP2

1.08e-0416026325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CORIN THBS2 COMP

1.20e-0416626337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CORIN THBS2 COMP

1.20e-0416626381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 THBS2 COMP

1.25e-041682634b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS2 THBS3

1.27e-041692638bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS2 THBS3

1.27e-04169263bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS2 THBS3

1.27e-041692635f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 THBS2 COMP

1.32e-041712635d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCelldroplet-Kidney-nan-21m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 C8A COMP

1.32e-04171263007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 C8A COMP

1.32e-041712638e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LRP1 VLDLR THBS2

1.36e-04173263b23b408acc29a667cce104429afef1a6cf2720a5
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 THBS4 COMP

1.41e-041752639d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS2 THBS4 COMP

1.41e-04175263f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCellfacs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 THBS1 THBS2

1.41e-0417526321542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LRP4 THBS2

1.43e-04176263c0a084f7a8645262d61971f094689e02bf15b113
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LRP4 THBS2

1.43e-04176263cccf9201f6e2da7524b911a5961d3b227edab222
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CORIN COMP

1.43e-041762639bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

LRP1 THBS2 LRP1B

1.43e-041762632e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CORIN COMP

1.43e-041762633f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR VLDLR DHX9

1.43e-04176263749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

LRP1 THBS2 LRP1B

1.43e-04176263f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(1)_Control_(PBS) / Stress and Cell class

LRP1 LRP4 VLDLR

1.46e-04177263d9e5ac5b8949a77e88e8094079167e4cf2c1bbd1
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

LRP1 THBS1 THBS2

1.48e-04178263142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

CORIN THBS2 COMP

1.48e-04178263edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

LRP1 LRP1B CD276

1.51e-04179263b4430f633711cecf793e8e76e766a66ff1eff473
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 COMP LRP1B

1.53e-0418026372310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCelldroplet-Limb_Muscle-nan-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS1 THBS4

1.53e-04180263d3d0be136fff5d3e39ecf5a5dbefc1d0d0a6c814
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP4 THBS2 COMP

1.56e-04181263b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VLDLR THBS2 THBS4

1.56e-04181263e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

CORIN THBS2 COMP

1.56e-04181263bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 VLDLR THBS1

1.58e-04182263ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 RXFP1 RXFP2

1.58e-0418226344764676ed3f51ba171ce63f669390392fa50a43
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRP4 THBS1 THBS2

1.58e-04182263ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR THBS1 DHX9

1.58e-04182263f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 RXFP1 RXFP2

1.58e-04182263d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

CORIN THBS1 THBS2

1.61e-0418326306e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COMP LRP1B PPM1E

1.63e-041842638fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 THBS2 RXFP1

1.63e-04184263e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR THBS1 DHX9

1.63e-041842631154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR THBS1 DHX9

1.66e-041852637adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

LRP4 VLDLR COMP

1.66e-0418526316f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORIN THBS2 THBS3

1.69e-04186263cd6502bbf9dce318fdbb4965d49df8951e5f795c
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORIN THBS2 THBS3

1.69e-04186263b58db5abdd3e9f0214b198c3cbd09b0b3c321eab
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 VLDLR THBS1

1.69e-04186263f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LRP1 THBS1 LRP1B

1.69e-0418626323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS2 THBS3 CD276

1.71e-04187263fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCellMesenchymal_cells-Ng2+_MSCs|Mesenchymal_cells / Lineage and Cell class

LRP4 VLDLR CD276

1.71e-04187263e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS1 THBS2 RXFP1

1.71e-0418726376bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS2 THBS3 THBS4

1.74e-04188263bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 LRP4 VLDLR

1.74e-041882633f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 THBS1 THBS2

1.74e-041882638cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS2 THBS3

1.77e-0418926356f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 THBS2 THBS3

1.77e-04189263544d95df910f1b276995624509a7e41b219baca0
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

THBS1 THBS2 TSPYL2

1.77e-041892633922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LRP4 VLDLR

1.77e-0418926340cbd679dc0548bf5207e1b033c0597886ad6fe1
ComputationalMetal / Ca ion binding.

LRP1 THBS2 THBS4 COMP

1.38e-04133224MODULE_324
Drugmonatepil

LRP1 LRP2 LRP4 LRP1B

2.64e-0829254CID000060810
DrugChr 5

LRP2 VLDLR THBS1 THBS4 COMP

2.24e-07125255CID006448119
Drugezetimibe

LRP1 LRP2 LRP4 LRP1B DHX9

5.02e-07147255CID000150311
Drugprobucol

LRP1 LRP2 LRP4 VLDLR LRP1B

8.12e-07162255CID000004912
DrugEpi Lovastatin

LRP1 LRP2 LRP4 VLDLR THBS1 LRP1B

1.50e-06341256CID000003962
DrugAC1OAGKW

LRP2 PIP4K2B THBS1 RXFP1 RXFP2

1.92e-06193255CID006857413
Drugsodium cholate

LRP1 LRP2 LRP4 THBS1 SAFB LRP1B

4.24e-06408256CID000000303
DrugLMWH

LRP1 LRP2 THBS1 THBS2 THBS3 THBS4 PES1

5.23e-06663257CID000000772
Drugvitamin E

LRP1 LRP2 LRP4 TPR VLDLR LRP1B

6.61e-06441256CID000002116
Drugpitavastatin

LRP1 LRP2 LRP4 LRP1B

6.95e-06114254CID005282451
DrugHepII

THBS1 COMP DHX9

1.40e-0543253CID003036269
Drugpristane

COMP NELFCD DHX9 CD276

2.17e-05152254CID000015979
DrugNor 3

THBS1 THBS2 THBS3

2.22e-0550253CID009578441
Drug25-hydroxycholesterol

LRP1 LRP2 LRP4 LRP1B

2.65e-05160254CID000065094
DrugFurosemide

THBS1 THBS2 THBS3 THBS4

2.92e-05164254ctd:D005665
Drug5224221; Up 200; 12uM; MCF7; HT_HG-U133A_EA

VLDLR THBS1 THBS3 PPM1E

4.11e-05179254839_UP
Drugcoprogen

LRP1 LRP2

4.15e-059252CID006323272
DrugAmoxicillin [26787-78-0]; Down 200; 11uM; MCF7; HT_HG-U133A

PIP4K2B THBS1 SAFB DHX9

4.67e-051852542620_DN
Drug17alpha-estradiol

LRP1 LRP2 LRP4 VLDLR THBS1 SAFB LRP1B DHX9

5.07e-051303258CID000000450
Drug25-azacoprostane

LRP1 LRP2

5.18e-0510252CID000162243
DrugPronethalol hydrochloride [51-02-5]; Down 200; 15uM; MCF7; HT_HG-U133A

LRP2 TPR THBS1 DHX9

5.40e-051922544104_DN
Drugsimvastatin

LRP1 LRP2 LRP4 THBS1 LRP1B

5.76e-05390255CID000054454
DrugAminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A

LRP2 TPR VLDLR THBS3

5.85e-051962545394_DN
DrugFlurandrenolide [1524-88-5]; Up 200; 9.2uM; PC3; HT_HG-U133A

LRP1 PIP4K2B THBS1 THBS3

5.85e-051962547378_UP
DrugEtofenamate [30544-47-9]; Down 200; 10.8uM; MCF7; HT_HG-U133A

TPR THBS1 THBS3 DHX9

5.85e-051962544108_DN
DrugPropidium iodide [25535-16-4]; Up 200; 6uM; MCF7; HT_HG-U133A

LRP2 PIP4K2B THBS1 SAFB

5.96e-051972546277_UP
DrugProchlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; PC3; HT_HG-U133A

LRP1 LRP4 THBS2 C8A

5.96e-051972546664_UP
DrugFlunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A

PIP4K2B VLDLR C8A PPM1E

6.08e-051982547013_UP
DrugHydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A

LRP2 THBS1 THBS3 TSPYL2

6.20e-051992545494_DN
Drugchondroitin sulfate

THBS1 THBS2 THBS3 THBS4 COMP

7.55e-05413255CID000024766
Drugdiethyl malate

THBS1 THBS2 COMP

1.13e-0486253ctd:C058705
DrugAC1L1J6H

LRP1 LRP2 LRP4 LRP1B

1.20e-04236254CID000004889
DrugRgd Peptide

THBS1 THBS2 THBS3 THBS4

1.26e-04239254CID000104802
Drugimidazoquinoline

THBS1 NELFCD CD276

1.82e-04101253CID005351568
DrugHepI

THBS1 DHX9

2.17e-0420252CID003036968
DrugCalpain inhibitor I

LRP1 LRP2 LRP4 LRP1B

2.31e-04280254CID000004332
Drugtroglitazone

LRP1 LRP2 LRP4 VLDLR LRP1B

2.34e-04526255CID000005591
Drugtetraphenylporphyrin

TPR THBS1

2.40e-0421252CID000070186
Drugdihydroacarbose

THBS3 THBS4 COMP

2.53e-04113253CID000174450
Drugfs x

THBS3 THBS4

2.89e-0423252CID000444420
Drugarginine butyrate

THBS1 TSPYL2

3.42e-0425252CID000054566
Drugdansylamide

TPR THBS4 C8A

3.56e-04127253CID000065077
Drugisocycloheximide

LRP1 LRP2 LRP4 THBS1 SAFB LRP1B

3.59e-04905256CID000002900
Drugtetrahydroaldosterone-3-glucuronide

LRP1 LRP2

4.61e-0429252CID000167918
Drug5br20686

SAFB PES1

4.61e-0429252CID000447088
Drugtrypanothione disulfide

THBS1 THBS2 NELFCD

4.74e-04140253CID000115098
Drugsodium linoleate

LRP1 LRP2 LRP4 LRP1B

4.93e-04342254CID000003931
DrugNe 2

SAFB COMP

4.94e-0430252CID000119346
Drug2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide

THBS1 THBS2

5.28e-0431252ctd:C577942
Drugraloxifene

THBS1 SAFB DHX9 CD276

5.44e-04351254CID000005035
Drugemtricitabine

RXFP1 RXFP2 DHX9

5.46e-04147253CID000060877
Drugepicholesterol

LRP1 LRP2 LRP4 VLDLR LRP1B

5.59e-04636255CID000000304
DrugAC1NX069

THBS1 THBS4

5.63e-0432252CID005716906
Drugbutyl benzyl phthalate

SAFB PES1

5.63e-0432252CID000002347
DrugABT510

THBS1 THBS4

5.63e-0432252CID006918562
DruguPA inhibitor

LRP1 LRP2

5.63e-0432252CID000001746
Drugbiphenylene

THBS1 THBS2

6.36e-0434252CID000009214
Druggeldanamycin

TPR VLDLR THBS1 DHX9

6.69e-04371254ctd:C001277
Drug15d-PGJ2; Up 200; 10uM; MCF7; HT_HG-U133A_EA

VLDLR PPM1E TSPYL2

6.87e-041592531011_UP
Drugthioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

PIP4K2B VLDLR THBS1

7.25e-041622531655_UP
Drugo-Phthalaldehyde

THBS1 THBS4

7.94e-0438252ctd:D009764
Drugthapsigargin; Up 200; 0.1uM; MCF7; HT_HG-U133A

TPR PPM1E TSPYL2

8.05e-041682537100_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

VLDLR PPM1E TSPYL2

8.34e-041702531631_UP
Drugthapsigargin; Up 200; 0.1uM; MCF7; HT_HG-U133A

VLDLR PPM1E TSPYL2

8.34e-041702537053_UP
DrugVal-Val

THBS1 THBS2

8.37e-0439252CID000107475
DrugAl per

C8A NELFCD

8.37e-0439252CID009576740
Druggeldanamycin; Up 200; 1uM; MCF7; HT_HG-U133A_EA

VLDLR PPM1E TSPYL2

8.92e-04174253972_UP
Drug2,6-dihydroxybenzoic acid

THBS1 RXFP1 RXFP2

9.06e-04175253CID000009338
Druggeldanamycin; Up 200; 1uM; MCF7; HT_HG-U133A

VLDLR PPM1E TSPYL2

9.06e-041752531653_UP
DrugAC1NAL8H

LRP1 SAFB

9.25e-0441252CID004478772
Drugpararosaniline base; Up 200; 10uM; MCF7; HT_HG-U133A_EA

VLDLR THBS3 PPM1E

9.37e-04177253893_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA

VLDLR PPM1E TSPYL2

9.52e-04178253916_UP
DrugDisulfiram [97-77-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A

VLDLR PPM1E TSPYL2

9.68e-041792536210_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA

VLDLR PPM1E TSPYL2

9.68e-041792531005_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA

VLDLR PPM1E TSPYL2

9.83e-04180253947_UP
Drug17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A

VLDLR THBS1 PPM1E

9.99e-041812535573_UP
DrugFenoterol hydrobromide [1944-12-3]; Up 200; 10.4uM; PC3; HT_HG-U133A

LRP2 PIP4K2B THBS1

1.02e-031822536331_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA

VLDLR PPM1E TSPYL2

1.02e-03182253998_UP
DrugMurabutida

NELFCD CD276

1.02e-0343252CID005362018
Drugdarifenicin

SAFB DHX9

1.02e-0343252CID000072054
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

VLDLR THBS1 TSPYL2

1.03e-031832536944_UP
DrugLY 294002; Down 200; 10uM; HL60; HT_HG-U133A

THBS4 PES1 TSPYL2

1.03e-031832532696_DN
Drugvalinomycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

TPR VLDLR PPM1E

1.05e-031842535957_UP
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA

VLDLR PPM1E TSPYL2

1.06e-03185253831_UP
DrugNaftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A

VLDLR THBS3 PPM1E

1.06e-031852533536_UP
DrugAlclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; HL60; HT_HG-U133A

THBS1 C8A PPM1E

1.06e-031852532532_UP
DrugNC-4

THBS1 COMP

1.06e-0344252CID006420119
Druglasofoxifene

SAFB DHX9

1.06e-0344252CID000216416
Drugmethoxyl

PES1 DHX9

1.06e-0344252CID000123146
DrugDicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A

TPR THBS1 DHX9

1.10e-031872534323_DN
DrugMometasone furoate [83919-23-7]; Up 200; 7.6uM; PC3; HT_HG-U133A

THBS1 C8A DHX9

1.10e-031872535116_UP
DiseaseMicroangiopathy, Diabetic

THBS1 THBS2

7.56e-0516242C0025945
DiseaseDiabetic Angiopathies

THBS1 THBS2

7.56e-0516242C0011875
Diseaseepilepsy (implicated_via_orthology)

LRP1 LRP1B DHX9

3.08e-04163243DOID:1826 (implicated_via_orthology)
Diseasepack-years measurement, systolic blood pressure

LRP2 LRP1B

3.50e-0434242EFO_0006335, EFO_0006526
Diseaseurate measurement

LRP1 LRP2 LRP4 THBS1 THBS3

6.68e-04895245EFO_0004531

Protein segments in the cluster

PeptideGeneStartEntry
NGDQDCLDGSDEDDC

C8A

116

P07357
VGDACDSDQDQDGDG

COMP

426

P49747
CEEENAGAEDQDGEG

CD276

496

Q5ZPR3
DGDNDCGDFSDEAQI

LRP1B

1026

Q9NZR2
CDGENDCGDNSDELD

LRP1B

2571

Q9NZR2
CDGENDCGDNSDELN

LRP1B

3376

Q9NZR2
WGDEADGGQQEDDSG

NELFCD

21

Q8IXH7
DGGQQEDDSGEGEDD

NELFCD

26

Q8IXH7
GDLLCDDDNEDQGDN

HNRNPCL3

251

B7ZW38
CDNDNDCGDNSDEAG

LRP1

996

Q07954
CDGNDDCGDGSDEGE

LRP1

1166

Q07954
NAMDADGGDDDDQGS

CAND1

321

Q86VP6
GDLLCDDDNEDQGDN

HNRNPCL4

251

P0DMR1
CDGEDDCKDNGDEDG

LRP2

241

P98164
LCDGDNDCGDNSDEN

LRP2

2841

P98164
GQEDGGDDKENHGEC

PPM1E

511

Q8WY54
GQADCDDDSDEENCG

CORIN

601

Q9Y5Q5
KDDDGGEDDDANCNL

DHX9

596

Q08211
RAEDEECENDGVGGN

PIP4K2B

301

P78356
DGKDDCGNGADEENC

RXFP2

66

Q8WXD0
EDNGLEENSGDGQED

SAFB

101

Q15424
ACDEDADGDGILNEQ

THBS4

506

P35443
KDGIGDACDDDDDND

THBS1

731

P07996
ADTDNNGEGDACAAD

THBS1

786

P07996
NGEGDACAADIDGDG

THBS1

791

P07996
DEDNDGNEGDNEGSD

TSPYL2

571

Q9H2G4
GNEGDNEGSDDDGNE

TSPYL2

576

Q9H2G4
NEGSDDDGNEGDNEG

TSPYL2

581

Q9H2G4
DDGNEGDNEGSDDDD

TSPYL2

586

Q9H2G4
NNEGDGDEEGENEEE

PES1

466

O00541
DGNDGYEADDAEGGD

TPR

1996

P12270
DDCGNQADEDNCGDN

RXFP1

51

Q9HBX9
QEDADNDGVGDQCDD

THBS3

491

P49746
NDGVGDQCDDDADGD

THBS3

496

P49746
KDTDGNGEGDACDND

THBS3

551

P49746
NGEGDACDNDVDGDG

THBS3

556

P49746
DNDGLGDECDGDDDN

THBS3

651

P49746
GDECDGDDDNDGIPD

THBS3

656

P49746
DGNGVGDVCEDDFDN

THBS3

691

P49746
GQGDACDPDDDNDGV

THBS2

891

P35442
GENDCDSGEDEENCG

VLDLR

136

P98155
GDNDCGDNSDEQCDM

LRP4

131

O75096