Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsoluble NSF attachment protein activity

NAPA NAPB

1.00e-053372GO:0005483
GeneOntologyBiologicalProcessSNARE complex disassembly

NAPA NAPB

9.38e-063372GO:0035494
GeneOntologyBiologicalProcessestablishment of planar polarity

LRP6 FAT4 RPGRIP1L

6.69e-0544373GO:0001736
GeneOntologyBiologicalProcessestablishment of tissue polarity

LRP6 FAT4 RPGRIP1L

7.16e-0545373GO:0007164
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

NAPA TSHZ3 NAPB SHANK3

8.99e-05132374GO:0035249
GeneOntologyBiologicalProcessmetencephalon development

LRP6 AARS1 RPGRIP1L ATF2

1.59e-04153374GO:0022037
GeneOntologyBiologicalProcessregulation of synaptic vesicle priming

NAPA NAPB

2.81e-0414372GO:0010807
GeneOntologyBiologicalProcessmorphogenesis of a polarized epithelium

LRP6 FAT4 RPGRIP1L

3.03e-0473373GO:0001738
GeneOntologyBiologicalProcessanimal organ morphogenesis

LRP6 FAT4 TSHZ3 SDK2 RPGRIP1L ATF2 TNC SHANK3 TLE1

3.18e-041269379GO:0009887
GeneOntologyCellularComponentsynaptobrevin 2-SNAP-25-syntaxin-1a complex

NAPA NAPB

3.04e-055372GO:0070044
DomainNSF_attach

NAPA NAPB

1.14e-053372IPR000744
DomainEGF_3

LRP6 FAT4 TNC TMEFF2

1.16e-03235374PS50026
DomainEGF

LRP6 FAT4 TNC TMEFF2

1.16e-03235374SM00181
DomainEGF-like_dom

LRP6 FAT4 TNC TMEFF2

1.44e-03249374IPR000742
DomainEGF_1

LRP6 FAT4 TNC TMEFF2

1.57e-03255374PS00022
DomainEGF-like_CS

LRP6 FAT4 TNC TMEFF2

1.71e-03261374IPR013032
DomainEGF_2

LRP6 FAT4 TNC TMEFF2

1.81e-03265374PS01186
DomainEGF

LRP6 TNC TMEFF2

1.97e-03126373PF00008
DomainC2

RPGRIP1L SYT14 PLCE1

2.20e-03131373PF00168
DomainC2

RPGRIP1L SYT14 PLCE1

2.50e-03137373SM00239
DomainC2

RPGRIP1L SYT14 PLCE1

2.77e-03142373PS50004
Domain-

RPGRIP1L SYT14 PLCE1

3.11e-031483732.60.40.150
DomainZINC_FINGER_C2H2_2

ZNF462 ZNF250 TSHZ3 GPATCH8 ATF2 ZNF45

3.87e-03775376PS50157
DomainZINC_FINGER_C2H2_1

ZNF462 ZNF250 TSHZ3 GPATCH8 ATF2 ZNF45

3.92e-03777376PS00028
Domainfn3

RIMBP2 SDK2 TNC

4.01e-03162373PF00041
DomainC2_dom

RPGRIP1L SYT14 PLCE1

4.15e-03164373IPR000008
DomainZnf_C2H2-like

ZNF462 ZNF250 TSHZ3 GPATCH8 ATF2 ZNF45

4.41e-03796376IPR015880
DomainZnf_C2H2

ZNF462 ZNF250 TSHZ3 GPATCH8 ATF2 ZNF45

4.66e-03805376IPR007087
DomainZnF_C2H2

ZNF462 ZNF250 TSHZ3 GPATCH8 ATF2 ZNF45

4.75e-03808376SM00355
DomainFN3

RIMBP2 SDK2 TNC

5.80e-03185373SM00060
DomainFN3

RIMBP2 SDK2 TNC

7.09e-03199373PS50853
DomainFN3_dom

RIMBP2 SDK2 TNC

8.11e-03209373IPR003961
DomainSH3

MAPK8IP1 RIMBP2 SHANK3

8.87e-03216373PS50002
DomainSH3

MAPK8IP1 RIMBP2 SHANK3

8.87e-03216373SM00326
DomainSH3_domain

MAPK8IP1 RIMBP2 SHANK3

9.33e-03220373IPR001452
DomainSH3_9

MAPK8IP1 RIMBP2

1.04e-0278372PF14604
DomainTPR-like_helical_dom

NAPA EEF2K NAPB

1.09e-02233373IPR011990
Domainzf-C2H2

ZNF462 ZNF250 TSHZ3 ATF2 ZNF45

1.13e-02693375PF00096
DomainSH3_2

RIMBP2 SHANK3

1.26e-0286372IPR011511
DomainSH3_2

RIMBP2 SHANK3

1.26e-0286372PF07653
Pubmed

SNAP family of NSF attachment proteins includes a brain-specific isoform.

NAPA NAPB

3.48e-0633828455721
Pubmed

A new beat for the SNARE drum.

NAPA NAPB

3.48e-0633829695844
Pubmed

Different attentional dysfunctions in eEF2K-/- , IL1RAPL1-/- and SHANK3Δ11-/- mice.

EEF2K SHANK3

3.48e-06338230838762
Pubmed

The N-ethylmaleimide-sensitive fusion protein (NSF) is preferentially expressed in the nervous system.

NAPA NAPB

3.48e-0633828013662
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF462 PHF2 NOL4 TSHZ3 GPATCH8 CTDSPL2 BRD9

3.80e-0660838736089195
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

ZNF462 TSHZ3 CXCR3 GPATCH8

4.96e-0610338432744500
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZNF462 USP34 ANKRD28 NOL4 TSHZ3 TLE1

5.80e-0641838634709266
Pubmed

A mutually stimulating loop involving emx2 and canonical wnt signalling specifically promotes expansion of occipital cortex and hippocampus.

LRP6 TSHZ3 TLE1

8.38e-063638315800025
Pubmed

A multisubunit particle implicated in membrane fusion.

NAPA NAPB

1.16e-0553821315316
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

USP34 ANKRD28 AARS1 RPGRIP1L GPATCH8 TLE1 AFAP1L1

1.28e-0573338734672954
Pubmed

Syntaxin 13 mediates cycling of plasma membrane proteins via tubulovesicular recycling endosomes.

NAPA NAPB

1.74e-0563829817754
Pubmed

The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs.

NAPA NAPB

1.74e-0563829697855
Pubmed

Human transcription factor protein interaction networks.

ZNF462 PHF2 LRP6 ANKRD28 NOL4 TSHZ3 GPATCH8 TLE1 BRD9

1.80e-05142938935140242
Pubmed

The gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) mice.

NAPA NAPB

3.24e-05838214755058
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF462 NOL4 TSHZ3 TLE1 BRD9

3.89e-0535138538297188
Pubmed

Seven novel mammalian SNARE proteins localize to distinct membrane compartments.

NAPA NAPB

4.16e-0593829553086
Pubmed

SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming.

NAPA NAPB

5.20e-051038221040848
Pubmed

Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion.

NAPA NAPB

5.20e-05103829914469
Pubmed

Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases.

MAPK8IP1 ATF2

6.35e-051138216533805
Pubmed

Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics.

ATF2 TLE1

6.35e-051138222439931
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NOL4 AARS1 TSHZ3 TLE1 BRD9

7.04e-0539838535016035
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ZNF462 PHF2 USP34 ANKRD28

1.06e-0422538412168954
Pubmed

The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate.

NAPA NAPB

1.38e-041638214758363
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TSHZ3 SDK2 PLCE1

1.97e-0410338310819331
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

ZNF462 USP34 TSHZ3 INTS7

2.51e-0428238423667531
Pubmed

Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.

MAPK8IP1 ATF2

2.65e-042238215767678
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

TSHZ3 RPGRIP1L GPATCH8

2.80e-0411638330804394
Pubmed

Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.

FAT4 TNC

3.16e-042438226116661
Pubmed

Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease.

TNC PLCE1

3.43e-042538226100917
Pubmed

Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.

ZNF462 SHANK3

4.96e-043038220080650
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ZNF462 MAPK8IP1 ANKRD28 RIMBP2 FRY SHANK3

5.74e-0496338628671696
Pubmed

GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.

TMEFF2 PLCE1

6.01e-043338221658281
Pubmed

CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.

CXCR3 TLE1 ISM1

7.56e-0416338323333304
Pubmed

Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter.

TSHZ3 TNC

7.97e-043838222833126
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

ANKRD28 TLE1 TBC1D9

8.11e-0416738325659891
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

AARS1 CTDSPL2 SHANK3 AFAP1L1 BRD9

8.79e-0468938536543142
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PHF2 LRP6 ANKRD28 RPGRIP1L CTDSPL2 ZNF330

8.97e-04104938627880917
Cytoband4q31.21

ZNF330 TBC1D9

2.14e-04263824q31.21
ToppCellmLN-ILC|mLN / Region, Cell class and subclass

ZNF462 ANKRD28 FRY TLE1 AFAP1L1

7.18e-07199385d6c299312c747fb1b7c53644c53efc03a5fffe85
ToppCellmLN-(3)_ILC|mLN / shred on region, Cell_type, and subtype

ZNF462 ANKRD28 FRY TLE1 AFAP1L1

7.18e-0719938500e0e2a766dd9c4d0a65f53d88fa50df4b6a3d60
ToppCellmLN-(3)_ILC-(30)_ILC|mLN / shred on region, Cell_type, and subtype

ZNF462 ANKRD28 FRY TLE1 AFAP1L1

7.18e-0719938533ac6d77099076df01299be429f4ba96f2f34cc1
ToppCellmLN-ILC-ILC|mLN / Region, Cell class and subclass

ZNF462 ANKRD28 FRY TLE1 AFAP1L1

7.18e-07199385ab09a06cdea2597e9fe4b4b304655e9de4d433f6
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF462 CXCR3 CD6 ZNF45

1.09e-05162384768a566e76923323c1f197f60bab472a8784490b
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

FRY TNC TLE1 PLCE1

1.34e-05171384e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

FRY TNC PLCE1 ISM1

1.38e-0517238436a96714a0eb6ac438648135336c9791881ddadb
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD28 CXCR3 CD6 TNC

1.38e-05172384d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD28 CXCR3 CD6 TNC

1.38e-0517238410a1d1838492b8ce6dea08844353b51571432c56
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

FRY TNC PLCE1 ISM1

1.61e-05179384e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF462 MAPK8IP1 TNC ISM1

1.99e-05189384d00410010283dc6191ce9857d6c7952678fed588
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

ANKRD28 FRY TLE1 AFAP1L1

2.12e-05192384e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

FAT4 TSHZ3 SDK2 TNC

2.16e-05193384acad568621ed677031797b8c2e34dafea798d681
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 TSHZ3 SDK2 TNC

2.21e-05194384011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NOL4 FAT4 TNC ISM1

2.25e-05195384f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NOL4 RIMBP2 TMEFF2 SYT14

2.34e-051973843a0e97bfebe82f9687d518baaad7f20d0ffea8a1
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF250 ANKRD28 CXCR3 CD6

2.34e-051973844bc76958ca12af2dd490d4865de6a92554a14656
ToppCell11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

TNC TLE1 TMEFF2 ISM1

2.34e-051973849a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FRY SHANK3 AFAP1L1 ISM1

2.39e-05198384218f33e068eb126458ec33176de3cfa6fc06ddf0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FRY SHANK3 AFAP1L1 ISM1

2.39e-05198384e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCellSepsis-URO-Lymphocyte-T/NK-CD4+_Tem|URO / Disease, condition lineage and cell class

HHLA2 CXCR3 CD6 ISM1

2.48e-052003848b7bfe6411de9528603481f6e5612cbbb8471cf6
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MAPK8IP1 TSHZ3 SDK2 TMEFF2

2.48e-05200384c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 CXCR3 CD6

2.20e-04138383321070b6900887b27da0f2b25808a05a8ab89ee7
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSHZ3 CXCR3 CD6

2.20e-0413838319ffd66256fa94d728138d37d0a5a3bac7722dbb
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSHZ3 TNC TMEFF2

2.44e-0414338357ee1830d96d73d92b5f83b028592a5d952c6013
ToppCellP15-Hematopoietic|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CXCR3 CD6 SYT14

2.60e-041463832b3e6ff6069573ee213000aeab5de9a33afc1a99
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HHLA2 FAT4 SYT14

2.76e-04149383c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HHLA2 FAT4 SYT14

2.76e-04149383a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOL4 RIMBP2 TMEFF2

3.10e-04155383498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellBac-SEP-Lymphocyte-T_NK-NK_CD56bright|Bac-SEP / Disease, Lineage and Cell Type

MAPK8IP1 CXCR3 ZNF45

3.28e-0415838320411158d71699a80f6c1566791af89dea0e1875
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NOL4 RIMBP2 SYT14

3.34e-041593837747cef94c55144fddcd024a7495318357f1351b
ToppCellBL-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RIMBP2 RPGRIP1L PLCE1

3.40e-041603833f737451d5713deed20061aa72a9ef77a9a2bc06
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CXCR3 CD6 SYT14

3.40e-04160383ec81814f3a475ba9bc049cb793bf93bc0b650d37
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAT4 CXCR3 TLE1

3.52e-041623839b1c07f0af657095379380c39d763cab0ad73e74
ToppCellT_cells-Tph_and_Tfh|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CXCR3 CD6 SYT14

3.52e-04162383146058f2d60846376078916055d08f68562e3a7c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ3 CD6 ISM1

3.52e-04162383f0a92c92c3a6cf9fa11fb279a584e7f328cb7d43
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ZNF462 MAPK8IP1 LRP6

3.52e-041623832259e9536147e9cdee772e3a30ba7d104573262c
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF250 ATF2 TMEFF2

3.52e-0416238356f1789e69a6cb29956e46aba92b290847327c1f
ToppCellmild-Myeloid-Eosinophils|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

EEF2K FRY AFAP1L1

3.59e-041633837c57d541a88e9afa079e95b8a6ecdea60a0c6aaa
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOL4 RIMBP2 SYT14

3.65e-04164383be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FRY TNC TLE1

3.72e-04165383f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|368C / Donor, Lineage, Cell class and subclass (all cells)

FRY SHANK3 AFAP1L1

3.78e-0416638376b4cd32698900797ec009f17e50ea7ae36b85f4
ToppCellBAL-Severe-cDC_2|Severe / Compartment, Disease Groups and Clusters

CXCR3 CD6 ISM1

3.78e-04166383602a72a607534d5f21eddd2c7a52a57084f4920f
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|368C / Donor, Lineage, Cell class and subclass (all cells)

FRY SHANK3 AFAP1L1

3.78e-0416638330a991fc3275b571d53bd0976df4789e5d40b01d
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZNF462 MAPK8IP1 LRP6

3.78e-0416638389e2b8453180983533faccb4275867861876d7ee
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOL4 RIMBP2 SYT14

3.85e-04167383c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|356C / Donor, Lineage, Cell class and subclass (all cells)

ANKRD28 CXCR3 CD6

3.92e-041683839d6ca10c272aea28082c09d469940f7232f6461c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 CD6 PLCE1

3.92e-041683832ab11cb9e691ac363e81f985e0450cdd721f9d7a
ToppCellfacs-GAT-Fat-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 CD6 TNC

3.92e-0416838328248e97165b0f0a272aed62f7d3898472992e15
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

SDK2 TNC ISM1

3.92e-0416838348089fa2d4a0f31a72405717119b767a92571f01
ToppCellInt-URO-Lymphocyte-T_NK-CD4_TEM|Int-URO / Disease, Lineage and Cell Type

CXCR3 CD6 ISM1

3.99e-041693835b2fb89cbc9b92d609994d6e5aa35a67c3cc8f22
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOL4 RIMBP2 SYT14

3.99e-04169383b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOL4 RIMBP2 SYT14

3.99e-0416938396a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RPGRIP1L PLCE1 ISM1

4.06e-04170383f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellLymphoid-Lymphoid-T_cells_(Cd8+_T_cell)|Lymphoid / shred on cell class and cell subclass (v4)

CXCR3 TNC PLCE1

4.06e-0417038320fd1a312c81c1bf3c5d2d6caf9b578e6b7a4171
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RIMBP2 FAT4 SDK2

4.06e-04170383b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 SHANK3 AFAP1L1

4.06e-0417038350c6c571591aa4b218caefe5778c570c809f567e
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ANKRD28 TLE1 AFAP1L1

4.06e-041703836c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCellsevere-Myeloid-Eosinophils|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

EEF2K FRY TLE1

4.06e-04170383863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 SHANK3 AFAP1L1

4.06e-041703838fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 SHANK3 AFAP1L1

4.06e-041703833232db50b1a40f861e981a1b9c9073b81af9f832
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CXCR3 RPGRIP1L CD6

4.06e-04170383070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCellHealthy/Control-MAIT|World / Disease group and Cell class

HHLA2 CD6 TLE1

4.13e-0417138361515114b17816a8f9ef6a57262eb9e977b6ede4
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 CD6 TNC

4.20e-04172383b440184f2d98d2f2d59566795f44fb79c0647ca4
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

SHANK3 TLE1 AFAP1L1

4.27e-04173383dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellHealthy/Control-MAIT|Healthy/Control / Disease group and Cell class

HHLA2 CD6 TLE1

4.27e-0417338356247c1e07477a8922fe2e3950ae05e2217fd77c
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ANKRD28 CXCR3 CD6

4.34e-0417438399d7421ad5eafe7751ef90698a92f683aa33bca8
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHF2 RIMBP2 SDK2

4.34e-04174383f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 SDK2 TMEFF2

4.34e-041743837d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRY TLE1 PLCE1

4.41e-041753831125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOL4 RIMBP2 SDK2

4.41e-04175383182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NOL4 RIMBP2 SYT14

4.41e-041753839941c35601134d88d1b3249c81f8b43a8fc61610
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD28 CXCR3 CD6

4.41e-04175383a72c6ceca5ddbd34f652e7302defefa2d105e17e
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD28 CXCR3 CD6

4.41e-041753839a462e9e6f7bbb64abb09ad6c080df3576073540
ToppCellfacs-Heart-RV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 SDK2 CD6

4.49e-041763833e7647364c13beade9ca278c7ce8e89546e0b060
ToppCellCF-Lymphoid-pDC|CF / Disease state, Lineage and Cell class

EEF2K CXCR3 SDK2

4.49e-04176383dd1e529a9e413bcaab43584afbe059e1464ffb53
ToppCellfacs-Heart-RV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 SDK2 CD6

4.49e-04176383a55572470de6af6cbf29ed4f785fdca62d24cd23
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK-NK_T_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ZNF462 CXCR3 CD6

4.49e-04176383f0c01fc4f9c17c4d724642d9931731eef2b10258
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK3 AFAP1L1 ISM1

4.56e-04177383b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 SHANK3 AFAP1L1

4.56e-041773838ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CXCR3 CD6 PLCE1

4.56e-0417738344c38e572a9e9678c2dbb3e8b4748e7e28d404b7
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHF2 RIMBP2 SDK2

4.64e-04178383fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 CD6 TNC

4.64e-04178383888add8935ef3aef9b6693c5698e9d1842e66337
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 CD6 TNC

4.64e-0417838343eda32af2e5e28a92421612d0a4c21e5427a772
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

NOL4 SDK2 SYT14

4.72e-04179383988d0853c391da1e5004f73f3678047418d3f6d3
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRY TLE1 PLCE1

4.72e-04179383111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NOL4 RIMBP2 TMEFF2

4.72e-04179383e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FRY SDK2 TNC

4.72e-04179383a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSHZ3 FRY SHANK3

4.72e-04179383d2db9e70b780643f1e004c41a70464d0abe26088
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17|GI_large-bowel / Manually curated celltypes from each tissue

FRY CXCR3 CD6

4.72e-041793836359f30005b17dc5b5c4c8f3a6a38c87ccfe4ee9
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|367C / Donor, Lineage, Cell class and subclass (all cells)

FRY SHANK3 AFAP1L1

4.79e-04180383162cec1734e560c068cd61717e40e18dcf92308c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOL4 RPGRIP1L PLCE1

4.79e-041803830c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOL4 RPGRIP1L PLCE1

4.79e-04180383e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCelldroplet-Marrow-BM-1m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CXCR3 CD6 AFAP1L1

4.79e-04180383ff34195bb7325e61fbf823c103c5e6115d8f1248
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1L TNC PLCE1

4.79e-04180383da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOL4 RPGRIP1L PLCE1

4.79e-0418038311455ba704ac73f69b474845136cfecec6a88349
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FRY SHANK3 AFAP1L1

4.79e-0418038333c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1L TNC PLCE1

4.79e-041803835b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCellIIH-CD4-exh_CD4|IIH / Condition, Cell_class and T cell subcluster

ANKRD28 CXCR3 CD6

4.79e-0418038331f22960819bfad79cbbd3b10c5dc46d7a47e340
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1L TNC PLCE1

4.79e-0418038350758b1e7be2e43f83c10ab106900c067e61f5f7
ComputationalNeighborhood of FOSL1

LRP6 FRY CXCR3 GPATCH8 CD6 ATF2

1.25e-04406226MORF_FOSL1
ComputationalNeighborhood of MLLT10

NOL4 FRY GPATCH8 ATF2 TLE1

3.01e-04302225MORF_MLLT10
ComputationalNeighborhood of PTEN

FRY GPATCH8 ATF2

6.59e-0485223MORF_PTEN
ComputationalNeighborhood of TFDP2

FRY GPATCH8 CD6 ATF2

1.10e-03230224MORF_TFDP2
ComputationalNeighborhood of MAGEA9

LRP6 FRY GPATCH8 CD6 ATF2

1.39e-03423225MORF_MAGEA9
Diseasememory impairment

FAT4 SHANK3

4.03e-058362EFO_0001072
DiseasePleural Diseases

CXCR3 TNC

6.47e-0510362C0032226
Diseaseextrinsic allergic alveolitis (is_marker_for)

CXCR3 TNC

1.30e-0414362DOID:841 (is_marker_for)
DiseaseCleft palate, cleft lip

PHF2 TLE1 TMEFF2 SYT14

3.63e-04279364EFO_0003959, HP_0000175
Diseasepulmonary sarcoidosis (is_marker_for)

CXCR3 TNC

7.01e-0432362DOID:13406 (is_marker_for)
DiseaseAbnormality of refraction

ZNF462 RIMBP2 TSHZ3 FRY SYT14

1.28e-03673365HP_0000539
Diseasecoronary artery calcification

ZNF462 LRP6 FRY TLE1

2.14e-03450364EFO_0004723
Diseasediabetes mellitus

TLE1 TMEFF2

3.13e-0368362EFO_0000400
Diseaseretinal vasculature measurement

RIMBP2 FRY SYT14 PLCE1

3.52e-03517364EFO_0010554

Protein segments in the cluster

PeptideGeneStartEntry
ENFSSSYDYGENESD

CXCR3

21

P49682
DSGYSSAHAEATYEE

CTDSPL2

236

Q05D32
GDHVNDSDTMKYYSE

CXorf66

321

Q5JRM2
ELSGSGHDSSYYDDR

BRD9

41

Q9H8M2
DSDSGDNADLYYSIT

FAT4

1341

Q6V0I7
HYAATSDTDGKCLEY

ANKRD28

476

O15084
KSGYHTADKDDSSED

ATF2

426

P15336
EYGSTGTAHADSEYE

INTS7

731

Q9NVH2
EDSDSGSDSDYEHYD

CD6

476

P30203
NYDKLYDSAFSAAHE

RPGRIP1L

361

Q68CZ1
GDYSDESDSATVYDN

MAPK8IP1

401

Q9UQF2
HKYSSSDDDYSLSCS

GPATCH8

926

Q9UKJ3
VHSYYKGSDHLESQD

HHLA2

71

Q9UM44
ATAKGYTSDLNYDSE

LRP6

1551

O75581
HSYSNRKYESDEDSL

EEF2K

461

O00418
YSNSSGGSYDEDKND

FRY

1576

Q5TBA9
GSLHYSDEDVTKYND

SDK2

2021

Q58EX2
ANSGDQDYKYDSTSD

ISM1

171

B1AKI9
SSAGQYAASDEEDAY

RIMBP2

696

O15034
YNSYMDKDEHGSSSE

SYT14

76

Q8NB59
AAYKSDDSSDEGSLH

PHF2

726

O75151
KSEDGHYARTDYAEN

TMEFF2

236

Q9UIK5
FEQSKEYDSHGSEDS

PLCE1

821

Q9P212
EYDSHGSEDSQKAFD

PLCE1

826

Q9P212
EQSADYYKGEESNSS

NAPA

146

P54920
HSYSSYDSGKNESVD

NOL4

356

O94818
SHSIVDGYYEDADSS

AFAP1L1

151

Q8TED9
DKDSSHYDSDGDKSD

TLE1

231

Q04724
SDYSDNLKYDHTTAC

ZNF250

96

P15622
TDDSPKYNYHLDSSG

AARS1

481

P49588
YDSLTSHSDYVIDDK

SHANK3

556

Q9BYB0
IYSDKEFAGSYNSSD

TBC1D9

406

Q6ZT07
YHNGRSFSTFDKDTD

TNC

2116

P24821
EQSADYYKGEESNSS

NAPB

146

Q9H115
SSKYHYLTENDLEES

TSHZ3

501

Q63HK5
DEEDYYGSSTNLKDH

ZNF462

796

Q96JM2
NLSSDKYGDTSYHDE

ZNF330

256

Q9Y3S2
VSDHSKDSESYEYDL

USP34

2136

Q70CQ2
DDLHYKDEGFSNQSS

ZNF45

136

Q02386