Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calmodulin binding	MYH11 ARPP21 MYLK MYO1A IQGAP2 MYO5A MYO7A SPTBN1 MYO5C IQGAP1 EEF2K TRPV1 MKNK1 EPB41	5.55e-08	230	193	14	GO:0005516
GeneOntologyMolecularFunction	actin binding	KIF18A MYH11 MYLK MYO1A IQGAP2 MYO5A MYO7A SPTBN1 MYO5C IQGAP1 MYO3B SYNE2 CGN PPP1R9A MYO18A WHAMM GSN STK38L EPB41	2.18e-07	479	193	19	GO:0003779
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF18A MYH11 MYLK MYO1A IQGAP2 MYO5A MYO7A DISC1 SPTBN1 APC2 PACSIN3 CCDC88B MAPK8IP3 MYO5C IQGAP1 FARP2 NDC80 MYO3B SYNE2 CGN MTCL1 JAKMIP1 PPP1R9A MYO18A WHAMM GSN STK38L EPB41 NIN	8.19e-07	1099	193	29	GO:0008092
GeneOntologyMolecularFunction	microfilament motor activity	MYH11 MYO1A MYO5A MYO7A MYO5C MYO3B	1.61e-06	38	193	6	GO:0000146
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF18A MYH11 MYO1A MYO5A MYO7A MYO5C MYO3B DNAH9 MYO18A	2.21e-06	118	193	9	GO:0003774
GeneOntologyMolecularFunction	actin filament binding	MYH11 MYO1A IQGAP2 MYO5A MYO7A SPTBN1 MYO5C IQGAP1 PPP1R9A MYO18A GSN	1.36e-05	227	193	11	GO:0051015
GeneOntologyMolecularFunction	MHC class II protein complex binding	HLA-DQB2 HLA-DRB3 HLA-DRB5 ANXA11	1.25e-04	27	193	4	GO:0023026
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	IQGAP2 RGPD1 PGAM5 IQGAP1 FARP2 HERC2 MCF2L DNMBP PREX1 RGPD5 RGPD8 ARHGEF18 OCRL RABEP1 GPSM3	1.28e-04	507	193	15	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	IQGAP2 RGPD1 PGAM5 IQGAP1 FARP2 HERC2 MCF2L DNMBP PREX1 RGPD5 RGPD8 ARHGEF18 OCRL RABEP1 GPSM3	1.28e-04	507	193	15	GO:0030695
GeneOntologyMolecularFunction	MHC class II receptor activity	HLA-DQB2 HLA-DRB3 HLA-DRB5	1.39e-04	11	193	3	GO:0032395
GeneOntologyMolecularFunction	kinase activity	HK2 MYLK PDK1 CLK4 BMPR1A MYO3B PKLR EEF2K DGKZ LCK MKNK1 MST1R FRK PALS1 PRKG2 PALS2 STK38L HCK	4.59e-04	764	193	18	GO:0016301
GeneOntologyMolecularFunction	MHC protein complex binding	HLA-DQB2 HLA-DRB3 HLA-DRB5 ANXA11	6.48e-04	41	193	4	GO:0023023
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	HK2 MYLK PDK1 CLK4 BMPR1A MYO3B PKLR EEF2K POLG DGKZ LCK MKNK1 MST1R FRK PALS1 NANS PRKG2 PALS2 STK38L HCK	7.83e-04	938	193	20	GO:0016772
GeneOntologyMolecularFunction	GTPase binding	IQGAP2 MYO5A SPTBN1 RGPD1 IQGAP1 RGPD8 PPP1R9A DVL3 WHAMM OCRL STRIP1	7.88e-04	360	193	11	GO:0051020
GeneOntologyMolecularFunction	ATP-dependent activity	KIF18A MYH11 ABCF3 MYO1A MYO5A MYO7A DHX38 MCM7 MYO5C MYO3B ABCD2 DNAH9 ABCC1 MYO18A TP53	9.57e-04	614	193	15	GO:0140657
GeneOntologyMolecularFunction	histone H2A ubiquitin ligase activity	UBR2 RNF2	1.36e-03	6	193	2	GO:0141053
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	HECW1 RGPD1 FBXW8 KLHL21 FBXO7 HERC2 UBE2E3 UBR2 RC3H2 RGPD8 WWP1 RNF2 PDZRN3	1.48e-03	512	193	13	GO:0019787
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	HK2 MYLK PDK1 CLK4 BMPR1A MYO3B PKLR EEF2K DGKZ LCK MKNK1 MST1R FRK PRKG2 STK38L HCK	1.49e-03	709	193	16	GO:0016773
GeneOntologyMolecularFunction	GTPase activator activity	IQGAP2 RGPD1 PGAM5 IQGAP1 PREX1 RGPD5 RGPD8 OCRL RABEP1	1.62e-03	279	193	9	GO:0005096
GeneOntologyBiologicalProcess	supramolecular fiber organization	KIF18A MYH11 MYO1A IQGAP2 MYO5A MYO7A USP9X SPTBN1 APC2 CCDC88B GFAP MYO5C IQGAP1 RHPN1 EEF2K PREX1 ADAMTS3 ADAMTS2 PPP1R9A WHAMM ARHGEF18 GSN CST2 HCK NIN	1.94e-06	957	187	25	GO:0097435
GeneOntologyBiologicalProcess	actin filament-based process	MYH11 MYO1A IQGAP2 MYO5A MYO7A SPTBN1 MYO5C IQGAP1 FARP2 RHPN1 MYO3B SYNE2 EEF2K PREX1 PPP1R9A MYO18A DVL3 WHAMM ARHGEF18 GSN STRIP1 PARD3 HCK EPB41	2.80e-06	912	187	24	GO:0030029
GeneOntologyBiologicalProcess	actin cytoskeleton organization	MYH11 MYO1A IQGAP2 MYO5A MYO7A SPTBN1 MYO5C IQGAP1 FARP2 RHPN1 MYO3B EEF2K PREX1 PPP1R9A MYO18A DVL3 WHAMM ARHGEF18 GSN STRIP1 HCK EPB41	3.97e-06	803	187	22	GO:0030036
GeneOntologyCellularComponent	myosin complex	MYH11 MYO1A MYO5A MYO7A MYO5C MYO3B CGN MYO18A	6.24e-08	59	191	8	GO:0016459
GeneOntologyCellularComponent	actin cytoskeleton	MYH11 MYLK ACACA MYO1A IQGAP2 MYO5A MYO7A SPTBN1 APC2 TMEM63B MYO5C IQGAP1 MYO3B CGN PPP1R9A MYO18A GSN MST1R STK38L HCK EPB41	7.79e-08	576	191	21	GO:0015629
GeneOntologyCellularComponent	cell leading edge	KIF18A MYLK MYO1A IQGAP2 MYO5A SPTBN1 APC2 MAPK8IP3 IQGAP1 SYNE2 MCF2L TRPV1 ATN1 PPP1R9A DGKZ GSN CSPG4	3.68e-06	500	191	17	GO:0031252
GeneOntologyCellularComponent	site of polarized growth	MYO1A MYO5A USP9X DISC1 MAPK8IP3 IQGAP1 PREX1 PPP1R9A FRY PARD3 NIN	2.23e-05	253	191	11	GO:0030427
GeneOntologyCellularComponent	growth cone	MYO1A MYO5A USP9X DISC1 MAPK8IP3 IQGAP1 PREX1 PPP1R9A PARD3 NIN	8.95e-05	245	191	10	GO:0030426
GeneOntologyCellularComponent	supramolecular fiber	KIF18A MYH11 MYO1A IQGAP2 MYO5A DISC1 SPTBN1 APC2 GFAP IQGAP1 KLHL21 SYNE2 MTCL1 JAKMIP1 DNAH9 MYO18A WHAMM HID1 GSN NARF CST2 TEKT4 HCK NIN	1.98e-04	1179	191	24	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KIF18A MYH11 MYO1A IQGAP2 MYO5A DISC1 SPTBN1 APC2 GFAP IQGAP1 KLHL21 SYNE2 MTCL1 JAKMIP1 DNAH9 MYO18A WHAMM HID1 GSN NARF CST2 TEKT4 HCK NIN	2.19e-04	1187	191	24	GO:0099081
GeneOntologyCellularComponent	vacuole	MANBA MYO5A MYO7A HLA-DQB2 ACP2 HLA-DRB3 HLA-DRB5 WDR81 GFAP TINAG RAB24 PTGES2 TPCN2 ANXA11 OCRL ENTPD4 MST1R FRK CSPG4 HCK	2.74e-04	913	191	20	GO:0005773
GeneOntologyCellularComponent	lamellipodium	MYLK IQGAP2 APC2 SYNE2 MCF2L PPP1R9A DGKZ GSN CSPG4	2.76e-04	230	191	9	GO:0030027
GeneOntologyCellularComponent	endoplasmic reticulum-Golgi intermediate compartment	INPP5B DCSTAMP GOLGB1 MYO18A WHAMM TMED3 PALS1	3.21e-04	141	191	7	GO:0005793
GeneOntologyCellularComponent	MHC class II protein complex	HLA-DQB2 HLA-DRB3 HLA-DRB5	4.65e-04	17	191	3	GO:0042613
GeneOntologyCellularComponent	lysosome	MANBA MYO5A MYO7A HLA-DQB2 ACP2 HLA-DRB3 HLA-DRB5 WDR81 GFAP TINAG PTGES2 TPCN2 ANXA11 OCRL ENTPD4 FRK CSPG4 HCK	4.79e-04	811	191	18	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	MANBA MYO5A MYO7A HLA-DQB2 ACP2 HLA-DRB3 HLA-DRB5 WDR81 GFAP TINAG PTGES2 TPCN2 ANXA11 OCRL ENTPD4 FRK CSPG4 HCK	4.79e-04	811	191	18	GO:0000323
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	KIF18A MYO1A IQGAP2 MYO5A DISC1 APC2 GFAP IQGAP1 KLHL21 MTCL1 JAKMIP1 DNAH9 WHAMM HID1 GSN NARF TEKT4 HCK NIN	6.05e-04	899	191	19	GO:0099513
GeneOntologyCellularComponent	cell cortex	MYO1A IQGAP2 MYO7A SPTBN1 IQGAP1 EXOC3L4 PPP1R9A GSN FRY PARD3 EPB41	6.38e-04	371	191	11	GO:0005938
GeneOntologyCellularComponent	lamellipodium membrane	APC2 SYNE2 CSPG4	1.02e-03	22	191	3	GO:0031258
GeneOntologyCellularComponent	cortical cytoskeleton	MYO1A SPTBN1 IQGAP1 PPP1R9A GSN EPB41	1.21e-03	129	191	6	GO:0030863
GeneOntologyCellularComponent	microtubule	KIF18A IQGAP2 DISC1 APC2 IQGAP1 KLHL21 MTCL1 JAKMIP1 DNAH9 WHAMM HID1 TEKT4 NIN	1.28e-03	533	191	13	GO:0005874
GeneOntologyCellularComponent	inclusion body	RGPD1 URB2 FBXO7 CARD14 RGPD8	1.42e-03	90	191	5	GO:0016234
GeneOntologyCellularComponent	cortical actin cytoskeleton	MYO1A SPTBN1 IQGAP1 PPP1R9A GSN	1.64e-03	93	191	5	GO:0030864
GeneOntologyCellularComponent	MHC protein complex	HLA-DQB2 HLA-DRB3 HLA-DRB5	1.67e-03	26	191	3	GO:0042611
GeneOntologyCellularComponent	lateral loop	PALS1 PARD3	1.69e-03	7	191	2	GO:0043219
GeneOntologyCellularComponent	microtubule organizing center	KIF18A HK2 USP9X DISC1 KIZ CCDC88B FBXW8 NDC80 HERC2 TSGA10IP EEF1AKMT3 MYO18A LCK FRY CEP131 CCDC65 TP53 NIN	1.97e-03	919	191	18	GO:0005815
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD1 RGPD8	2.24e-03	8	191	2	GO:1990723
GeneOntologyCellularComponent	distal axon	MYO1A MYO5A USP9X DISC1 MAPK8IP3 IQGAP1 PREX1 POLG PPP1R9A PARD3 NIN	2.27e-03	435	191	11	GO:0150034
GeneOntologyCellularComponent	RNA N6-methyladenosine methyltransferase complex	RBM15B RBM15	2.87e-03	9	191	2	GO:0036396
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	SPTBN1 EPB41	2.87e-03	9	191	2	GO:0014731
GeneOntologyCellularComponent	endocytic vesicle	HLA-DQB2 INPP5B HLA-DRB3 HLA-DRB5 ANXA11 MYO18A OCRL LCK GSN RABEP1	2.89e-03	384	191	10	GO:0030139
MousePheno	increased hepatocellular carcinoma incidence	EAF2 IQGAP2 ACOX1 SPTBN1 RGPD1 RGPD8 UACA TP53	9.11e-07	70	153	8	MP:0003331
MousePheno	increased hepatobiliary system tumor incidence	EAF2 IQGAP2 ACOX1 SPTBN1 RGPD1 RGPD8 UACA TP53	2.92e-05	111	153	8	MP:0010297
MousePheno	increased liver tumor incidence	EAF2 IQGAP2 ACOX1 SPTBN1 RGPD1 RGPD8 UACA TP53	2.92e-05	111	153	8	MP:0008019
MousePheno	abnormal Purkinje cell dendrite morphology	MYO5A ACP2 WDR81 MTCL1 HERC2 STK38L	3.94e-05	58	153	6	MP:0008572
Domain	IQ	MYH11 MYO1A IQGAP2 MYO5A MYO7A MYO5C IQGAP1 MYO3B MYO18A CEP131	2.52e-09	71	190	10	PF00612
Domain	IQ	MYH11 MYO1A IQGAP2 MYO5A MYO7A MYO5C IQGAP1 MYO3B MYO18A CEP131	9.41e-09	81	190	10	SM00015
Domain	IQ_motif_EF-hand-BS	MYH11 MYO1A IQGAP2 MYO5A MYO7A MYO5C IQGAP1 MYO3B MYO18A CEP131	2.65e-08	90	190	10	IPR000048
Domain	IQ	MYH11 MYO1A IQGAP2 MYO5A MYO7A MYO5C IQGAP1 MYO3B MYO18A CEP131	3.64e-08	93	190	10	PS50096
Domain	Myosin_head_motor_dom	MYH11 MYO1A MYO5A MYO7A MYO5C MYO3B MYO18A	9.76e-08	38	190	7	IPR001609
Domain	MYOSIN_MOTOR	MYH11 MYO1A MYO5A MYO7A MYO5C MYO3B MYO18A	9.76e-08	38	190	7	PS51456
Domain	Myosin_head	MYH11 MYO1A MYO5A MYO7A MYO5C MYO3B MYO18A	9.76e-08	38	190	7	PF00063
Domain	MYSc	MYH11 MYO1A MYO5A MYO7A MYO5C MYO3B MYO18A	9.76e-08	38	190	7	SM00242
Domain	PDZ	RHPN1 PREX1 CARD14 PPP1R9A MYO18A DVL3 PALS1 PALS2 PARD3 PDZRN3	2.83e-06	148	190	10	SM00228
Domain	-	RHPN1 PREX1 CARD14 PPP1R9A MYO18A DVL3 PALS1 PALS2 PARD3 PDZRN3	3.20e-06	150	190	10	2.30.42.10
Domain	PDZ	RHPN1 PREX1 CARD14 PPP1R9A MYO18A DVL3 PALS1 PALS2 PARD3 PDZRN3	3.39e-06	151	190	10	PS50106
Domain	PDZ	RHPN1 PREX1 CARD14 PPP1R9A MYO18A DVL3 PALS1 PALS2 PARD3 PDZRN3	3.60e-06	152	190	10	IPR001478
Domain	Myosin_S1_N	MYH11 MYO5A MYO5C	1.02e-05	5	190	3	IPR008989
Domain	SPOC_C	RBM15B RBM15 DIDO1	2.03e-05	6	190	3	IPR012921
Domain	SPOC	RBM15B RBM15 DIDO1	2.03e-05	6	190	3	PF07744
Domain	Myosin-like_IQ_dom	MYH11 MYO5C IQGAP1 MYO18A	3.57e-05	19	190	4	IPR027401
Domain	-	MYH11 MYO5C IQGAP1 MYO18A	3.57e-05	19	190	4	4.10.270.10
Domain	P-loop_NTPase	GIMAP4 KIF18A TRIT1 MYH11 ABCF3 MYO1A MYO5A MYO7A DHX38 MCM7 MYO5C IQGAP1 TRANK1 RAB24 MYO3B ABCD2 DNAH9 CARD14 ABCC1 MYO18A PALS1 PALS2	5.39e-05	848	190	22	IPR027417
Domain	MHC_II_b_N	HLA-DQB2 HLA-DRB3 HLA-DRB5	5.59e-05	8	190	3	PD000328
Domain	MHC_II_b_N	HLA-DQB2 HLA-DRB3 HLA-DRB5	8.32e-05	9	190	3	IPR000353
Domain	MHC_II_beta	HLA-DQB2 HLA-DRB3 HLA-DRB5	8.32e-05	9	190	3	SM00921
Domain	MHC_II_beta	HLA-DQB2 HLA-DRB3 HLA-DRB5	8.32e-05	9	190	3	PF00969
Domain	PDZ	RHPN1 PPP1R9A MYO18A DVL3 PALS1 PALS2 PARD3 PDZRN3	9.89e-05	141	190	8	PF00595
Domain	Grip	RGPD1 RGPD5 RGPD8	1.61e-04	11	190	3	SM00755
Domain	GRIP	RGPD1 RGPD5 RGPD8	1.61e-04	11	190	3	PF01465
Domain	Ran_BP1	RGPD1 RGPD5 RGPD8	2.13e-04	12	190	3	PF00638
Domain	RANBD1	RGPD1 RGPD5 RGPD8	2.13e-04	12	190	3	PS50196
Domain	GRIP_dom	RGPD1 RGPD5 RGPD8	2.13e-04	12	190	3	IPR000237
Domain	GRIP	RGPD1 RGPD5 RGPD8	2.13e-04	12	190	3	PS50913
Domain	RanBD	RGPD1 RGPD5 RGPD8	2.75e-04	13	190	3	SM00160
Domain	Ran_bind_dom	RGPD1 RGPD5 RGPD8	2.75e-04	13	190	3	IPR000156
Domain	RasGAP_C	IQGAP2 IQGAP1	3.07e-04	3	190	2	IPR000593
Domain	RasGAP_C	IQGAP2 IQGAP1	3.07e-04	3	190	2	PF03836
Domain	SUZ	ARPP21 R3HDM1	3.07e-04	3	190	2	PF12752
Domain	SPOC_met	RBM15B RBM15	3.07e-04	3	190	2	IPR010912
Domain	MHC_II_a/b_N	HLA-DQB2 HLA-DRB3 HLA-DRB5	3.47e-04	14	190	3	IPR014745
Domain	-	HLA-DQB2 HLA-DRB3 HLA-DRB5	3.47e-04	14	190	3	3.10.320.10
Domain	SH3	MYO7A PACSIN3 MCF2L DNMBP LCK FRK PALS1 PALS2 HCK	3.78e-04	216	190	9	SM00326
Domain	SH3	MYO7A PACSIN3 MCF2L DNMBP LCK FRK PALS1 PALS2 HCK	3.78e-04	216	190	9	PS50002
Domain	SH3_domain	MYO7A PACSIN3 MCF2L DNMBP LCK FRK PALS1 PALS2 HCK	4.32e-04	220	190	9	IPR001452
Domain	PH_dom-like	MYO7A NBEAL1 SPTBN1 RGPD1 PLEKHS1 FARP2 MCF2L PREX1 RGPD5 IRS4 RGPD8 ARHGEF18 EPB41	4.36e-04	426	190	13	IPR011993
Domain	DH_1	FARP2 MCF2L DNMBP PREX1 ARHGEF18	4.50e-04	63	190	5	PS00741
Domain	SUZ	ARPP21 R3HDM1	6.09e-04	4	190	2	IPR024771
Domain	SUZ	ARPP21 R3HDM1	6.09e-04	4	190	2	PS51673
Domain	SPOC	RBM15B RBM15	6.09e-04	4	190	2	PS50917
Domain	RhoGEF	FARP2 MCF2L DNMBP PREX1 ARHGEF18	6.41e-04	68	190	5	SM00325
Domain	GDS_CDC24_CS	FARP2 MCF2L DNMBP PREX1	6.46e-04	39	190	4	IPR001331
Domain	RhoGEF	FARP2 MCF2L DNMBP PREX1 ARHGEF18	7.32e-04	70	190	5	PF00621
Domain	DH_2	FARP2 MCF2L DNMBP PREX1 ARHGEF18	7.32e-04	70	190	5	PS50010
Domain	Myosin_tail_1	MYH11 CGN MYO18A	7.56e-04	18	190	3	PF01576
Domain	Myosin_tail	MYH11 CGN MYO18A	7.56e-04	18	190	3	IPR002928
Domain	-	FARP2 MCF2L DNMBP PREX1 ARHGEF18	7.82e-04	71	190	5	1.20.900.10
Domain	DH-domain	FARP2 MCF2L DNMBP PREX1 ARHGEF18	7.82e-04	71	190	5	IPR000219
Domain	-	RBM15B RBM15	1.01e-03	5	190	2	2.40.290.10
Domain	SPOC-like_C_dom	RBM15B RBM15	1.01e-03	5	190	2	IPR016194
Domain	Dilute_dom	MYO5A MYO5C	1.50e-03	6	190	2	IPR002710
Domain	DIL	MYO5A MYO5C	1.50e-03	6	190	2	PF01843
Domain	DILUTE	MYO5A MYO5C	1.50e-03	6	190	2	PS51126
Domain	DIL	MYO5A MYO5C	1.50e-03	6	190	2	SM01132
Domain	Spectrin	SPTBN1 SYNE2 MCF2L	1.58e-03	23	190	3	PF00435
Domain	GUANYLATE_KINASE_2	CARD14 PALS1 PALS2	1.58e-03	23	190	3	PS50052
Domain	GUANYLATE_KINASE_1	CARD14 PALS1 PALS2	1.58e-03	23	190	3	PS00856
Domain	Protein_kinase_ATP_BS	MYLK CLK4 BMPR1A MYO3B LCK MKNK1 MST1R FRK PRKG2 STK38L HCK	1.78e-03	379	190	11	IPR017441
Domain	WW_DOMAIN_1	HECW1 IQGAP2 IQGAP1 WWP1	1.79e-03	51	190	4	PS01159
Domain	WW_DOMAIN_2	HECW1 IQGAP2 IQGAP1 WWP1	1.79e-03	51	190	4	PS50020
Domain	WW_dom	HECW1 IQGAP2 IQGAP1 WWP1	1.92e-03	52	190	4	IPR001202
Domain	Rab_bind	RGPD1 RGPD8	2.09e-03	7	190	2	PF16704
Domain	GCC2_Rab_bind	RGPD1 RGPD8	2.09e-03	7	190	2	IPR032023
Domain	Guanylate_kin	CARD14 PALS1 PALS2	2.27e-03	26	190	3	PF00625
Domain	GK/Ca_channel_bsu	CARD14 PALS1 PALS2	2.27e-03	26	190	3	IPR008145
Domain	Guanylate_kin-like_dom	CARD14 PALS1 PALS2	2.27e-03	26	190	3	IPR008144
Domain	GuKc	CARD14 PALS1 PALS2	2.27e-03	26	190	3	SM00072
Domain	-	MYO7A SPTBN1 RGPD1 PLEKHS1 FARP2 MCF2L PREX1 IRS4 RGPD8 ARHGEF18 EPB41	2.27e-03	391	190	11	2.30.29.30
Domain	HECT	HECW1 HERC2 WWP1	2.53e-03	27	190	3	PF00632
Domain	HECTc	HECW1 HERC2 WWP1	2.53e-03	27	190	3	SM00119
Domain	HECT_dom	HECW1 HERC2 WWP1	2.53e-03	27	190	3	IPR000569
Domain	HECT	HECW1 HERC2 WWP1	2.53e-03	27	190	3	PS50237
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	KIF18A MYH11 MYLK EPSTI1 IQGAP2 USP9X SPTBN1 RGPD1 IQGAP1 FARP2 RHPN1 NDC80 MCF2L DNMBP PREX1 RGPD8 DVL3 WHAMM ARHGEF18 OCRL LCK CPSF7	6.85e-07	649	144	22	MM15690
Pathway	REACTOME_RHO_GTPASE_CYCLE	EPSTI1 IQGAP2 USP9X SPTBN1 WDR81 IQGAP1 FARP2 RHPN1 MCF2L DNMBP PREX1 UACA WHAMM ARHGEF18 OCRL LCK CPSF7	3.42e-06	450	144	17	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	KIF18A MYH11 MYLK EPSTI1 IQGAP2 USP9X SPTBN1 WDR81 IQGAP1 FARP2 RHPN1 NDC80 MCF2L DNMBP PREX1 UACA DVL3 WHAMM ARHGEF18 OCRL LCK CPSF7	3.79e-06	720	144	22	M41838
Pathway	REACTOME_RHO_GTPASE_CYCLE	EPSTI1 IQGAP2 USP9X SPTBN1 IQGAP1 FARP2 RHPN1 MCF2L DNMBP PREX1 WHAMM ARHGEF18 OCRL LCK CPSF7	4.29e-05	439	144	15	MM15595
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	HECW1 IQGAP2 MYO5A USP9X SPTBN1 APC2 RGPD1 WDR81 PGAM5 MAPK8IP3 IQGAP1 ZNF394 SYNE2 MTCL1 JAKMIP1 HERC2 GOLGB1 RGPD8 UACA PPP1R9A ARHGEF18 DIDO1 DGKZ WDR26 GSN STRIP1 PALS1 FRY RABEP1 SAFB2 CEP131 PARD3	5.78e-16	963	195	32	28671696
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	IQGAP2 MYO5A USP9X LAMA1 MCM7 FARP2 BMPR1A PELO RBM15B HERC2 RBM15 ZCCHC8 WWP1 PARD3 TP53	3.39e-10	313	195	15	38270169
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	KIF18A USP9X MCM7 PGAM5 PPP1R9A DVL3 WDR26 GSN STRIP1 PALS1 RABEP1 PALS2 PARD3 STK38L	4.83e-10	270	195	14	24366813
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	USP9X PGAM5 CRLF3 CGN MTCL1 RBM15 IRS4 ZCCHC8 PPP1R9A STRIP1 PALS1 RABEP1 CEP131 R3HDM1 PARD3 STK38L NIN	7.35e-10	446	195	17	24255178
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ACACA SPTBN1 MAPK8IP3 IQGAP1 SAFB RBM15B ZBTB40 DNMBP UBE2E3 HOMEZ RBM15 ATN1 UACA ZCCHC8 MYO18A DIDO1 STRIP1 ZNF106 SAFB2 PARD3 PHF10	3.17e-09	774	195	21	15302935
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	HECW1 HLA-DRB5 APC2 CCDC88B GFAP MAPK8IP3 JAG2 FBXO7 KAZN JAKMIP1 ATN1 RGPD8 PUF60 WWP1 DVL3 SAFB2 R3HDM1 TP53	3.36e-09	560	195	18	21653829
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	MYO5A USP9X PACSIN3 MCM7 URB2 PGAM5 MYO5C IQGAP1 FBXW8 SAFB SYNE2 CGN HERC2 GOLGB1 RBM15 IRS4 PUF60 PPP1R9A ANXA11 GSN SAFB2 CEP131 TP53 CPSF7	3.91e-09	1024	195	24	24711643
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	HECW1 TRANK1 HERC2 MCF2L DNAH9 UBR2 ADAMTS3 DIDO1 ENTPD4	7.90e-09	104	195	9	9205841
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ACACA PDK1 PACSIN3 ITGA7 CEMIP2 FARP2 GOLGB1 ABCC1 IRS4 UACA PPP1R9A OCRL PALS1 PALS2 PARD3	1.87e-08	421	195	15	36976175
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ACACA MYO5A USP9X SPTBN1 DHX38 URB2 PGAM5 IQGAP1 SYNE2 CGN HERC2 RBM15 IRS4 PUF60 ZCCHC8 ANXA11 DIDO1 TP53	3.53e-08	653	195	18	22586326
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CWF19L2 USP9X DHX38 MCM7 PGAM5 PELO NDC80 DNMBP GOLGB1 RBM15 RGPD8 ZCCHC8 RABEP1 CEP131 TP53 CPSF7 NIN	4.36e-08	588	195	17	38580884
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MYO5A PDK1 EXOSC5 URB2 JAKMIP1 HERC2 GOLGB1 ABCC1 PTGES2 UACA PEX3 MYO18A WDR26 GSN SNIP1 CEP131 R3HDM1 TP53 NIN	5.93e-08	754	195	19	33060197
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ACACA SPTBN1 HJURP SYNE2 CGN MTCL1 DNMBP GOLGB1 RBM15 IRS4 ZCCHC8 LCK WDR26 ZNF106 RABEP1 CEP131 R3HDM1 PARD3 EPB41 TP53	9.76e-08	861	195	20	36931259
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ACACA USP9X MCM7 PGAM5 CGN RGPD5 IRS4 PUF60 DIDO1 PALS1 MTRF1 RNF2 RABEP1 PARD3 EPB41 TP53	9.91e-08	549	195	16	38280479
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH11 MYLK MYO1A IQGAP2 MYO5A SPTBN1 RGPD1 PGAM5 IQGAP1 BMPR1A SAFB SYNE2 JAKMIP1 MCF2L PREX1 GOLGB1 RGPD5 IRS4 RGPD8 PCDHGC5 PPP1R9A MYO18A RNF2 CSPG4 SAFB2 PCDHGC3	1.64e-07	1442	195	26	35575683
Pubmed	p53 Promotes chemoresponsiveness by regulating hexokinase II gene transcription and metabolic reprogramming in epithelial ovarian cancer.	HK2 PDK1 TP53	1.74e-07	3	195	3	31486135
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	SPTBN1 PGAM5 FARP2 CGN JAKMIP1 IRS4 PUF60 RABEP1 PARD3 STK38L TP53	2.36e-07	255	195	11	15324660
Pubmed	Identification of FBXO25-interacting proteins using an integrated proteomics approach.	MYH11 MYO1A MYO5A MCM7 GFAP IQGAP1 UACA GSN	2.44e-07	112	195	8	20473970
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ACACA MYO5A KIZ TSPYL2 TMEM63B NSRP1 MAPK8IP3 FARP2 JAG2 TMX3 MCF2L UBE2E3 GOLGB1 UBR2 TPCN2 UACA WWP1 POLG PPP1R9A ARHGEF18 NACC2 RABEP1 PALS2 PARD3 STK38L EPB41	3.03e-07	1489	195	26	28611215
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ABCF3 ACACA MATN2 SPTBN1 MCM7 PGAM5 IQGAP1 BMPR1A PELO CGN OXSM UBR2 RBM15 ATN1 UACA PUF60 WWP1 DVL3 PALS1 RNF2 WDR87 PARD3 CPSF7	6.11e-07	1247	195	23	27684187
Pubmed	SAFB1 interacts with and suppresses the transcriptional activity of p53.	SAFB SAFB2 TP53	6.91e-07	4	195	3	21130767
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ACACA RGPD1 MCM7 GOLGB1 HOMEZ IRS4 RGPD8 LCORL ZCCHC8 DVL3 WDR26 RABEP1 CEP131	7.92e-07	418	195	13	34709266
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO1A MYO5A MYO7A MYO5C	9.18e-07	14	195	4	8022818
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYO5A USP9X SPTBN1 APC2 TSPYL2 ZNF202 GFAP MAPK8IP3 IQGAP1 FBXO7 JAKMIP1 HERC2 PREX1 PTGES2 ZCCHC8 POLG DVL3 WHAMM WDR26 FRY RABEP1 PALS2 R3HDM1	1.02e-06	1285	195	23	35914814
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SPTBN1 NSRP1 IQGAP1 SAFB CGN GOLGB1 RBM15 PPP1R9A DIDO1 GSN RABEP1 CPSF7	1.03e-06	360	195	12	33111431
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MYO5A CLK4 DHX38 PACSIN3 EXOSC5 URB2 IQGAP1 FARP2 RBM15B HERC2 DNMBP PREX1 GOLGB1 UACA ZCCHC8 PPP1R9A WHAMM DIDO1 DGKZ STRIP1 SNIP1 RNF2 CEP131 PARD3 EPB41	1.17e-06	1497	195	25	31527615
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	USP9X MCM7 SYNE2 RBM15B IRS4 ATN1 ARHGEF18 RNF2 CEP131	1.88e-06	197	195	9	20811636
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	MYH11 MYO5A MATN2 SPTBN1 MCM7 PGAM5 NSRP1 MYO5C IQGAP1 SAFB RBM15 UACA PUF60 PPP1R9A MYO18A GSN SNIP1 SAFB2 EPB41	1.90e-06	949	195	19	36574265
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	HK2 ACACA HECW1 MATN2 TSPYL2 JAG2 KAZN UBE2E3 ATN1 PUF60 WWP1 MYO18A R3HDM1 TP53 CPSF7	2.01e-06	608	195	15	16713569
Pubmed	The protein interaction landscape of the human CMGC kinase group.	USP9X CLK4 LAMA1 WDR81 MCM7 EXOSC5 NSRP1 IQGAP1 HERC2 RBM15 ZCCHC8 DIDO1 MKNK1 FRY PRKG2 TP53	2.22e-06	695	195	16	23602568
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH11 ACACA MYO5A MYO5C IQGAP1 HERC2 UACA MYO18A TP53	2.31e-06	202	195	9	33005030
Pubmed	Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.	FARP2 MCF2L DNMBP ARHGEF18	2.76e-06	18	195	4	12799088
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	HK2 ABCF3 ACACA USP9X DHX38 MCM7 PGAM5 SAFB PELO RBM15 PUF60 LCK SAFB2 PALS2 CPSF7	4.77e-06	653	195	15	33742100
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	HJURP MCM7 PGAM5 FBXW8 NDC80 KLHL21 FBXO7 RC3H2 ATN1 DIDO1 RNF2 CST2 TP53	5.05e-06	495	195	13	27705803
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD1 RGPD5 RGPD8	5.98e-06	7	195	3	15710750
Pubmed	Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.	MYO5A MYO7A FARP2 PEX3 SNIP1	9.09e-06	50	195	5	24721909
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	NSRP1 SAFB PUF60 ZCCHC8 DIDO1 SAFB2 CPSF7	9.23e-06	130	195	7	35545047
Pubmed	Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF.	CGN ARHGEF18 PARD3	9.52e-06	8	195	3	22006950
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MYH11 IQGAP2 SPTBN1 PACSIN3 PGAM5 IQGAP1 CGN RBM15B HERC2 RC3H2 RBM15 UACA PUF60 DIDO1 C2orf68 SNIP1 RNF2 CEP131 PARD3 PHF10 TP53 CPSF7	1.01e-05	1371	195	22	36244648
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	ARPP21 EEF2K LCK R3HDM1 PARD3 HCK CPSF7	1.07e-05	133	195	7	15144186
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ABCF3 IQGAP2 INPP5B SPTBN1 DHX38 HJURP BMPR1A EXOC3L4 FBXO7 ZBTB40 TMX3 GOLGB1 WWP1 POLG ARHGEF18 DIDO1 DGKZ SAFB2 PARD3	1.26e-05	1084	195	19	11544199
Pubmed	Report and abstracts of the third international workshop on human chromosome 16 mapping 1994. Pittsburgh, Pennsylvania, May 7-9, 1994.	MYH11 ABCC1 PRM2	1.42e-05	9	195	3	7842732
Pubmed	Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.	MYO7A DNMBP FRK PALS2 HCK	1.59e-05	56	195	5	22745667
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MYO1A DHX38 PGAM5 IQGAP1 SAFB FBXO7 PKLR MTCL1 HERC2 TMX3 RGPD5 RBM15 PPP1R9A WDR26 STRIP1 PALS1 TP53 NIN	1.62e-05	1005	195	18	19615732
Pubmed	Diminished Ventral Oligodendrocyte Precursor Generation Results in the Subsequent Over-production of Dorsal Oligodendrocyte Precursors of Aberrant Morphology and Function.	GFAP NKX2-2 CSPG4	2.02e-05	10	195	3	32450295
Pubmed	HIV/SIV escape from immune surveillance: focus on Nef.	HLA-DQB2 LCK HCK TP53	2.04e-05	29	195	4	15078178
Pubmed	Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.	RGPD1 IQGAP1 RGPD8 UACA PARD3 CPSF7	2.09e-05	99	195	6	27746211
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	MYO5A MYO7A SPTBN1 HLA-DRB5 PACSIN3 FARP2 ZNF394 KLHL21 CRLF3 FBXO7 KAZN MCF2L HOMEZ PTGES2 ADAMTS3 PEX3 ARHGEF18 SNIP1 ZNF106 NACC2	2.49e-05	1242	195	20	30973865
Pubmed	Functional genomics identifies therapeutic targets for MYC-driven cancer.	KIF18A MYLK PDK1 BMPR1A MYO3B HCK	2.62e-05	103	195	6	22623531
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	SPTBN1 SAFB IRS4 UACA ZCCHC8 PPP1R9A MYO18A PALS1 R3HDM1	2.67e-05	274	195	9	34244482
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	IQGAP2 MCM7 MYO5C FBXW8 PELO UBR2 PTGES2 IRS4	2.73e-05	211	195	8	17314511
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	KIF18A MYO5A USP9X SPTBN1 DHX38 CEMIP2 CRLF3 SYNE2 CGN HERC2 UBR2 ABCC1 RBM15 IRS4 PPP1R9A HID1 CEP131 NIN	2.84e-05	1049	195	18	27880917
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	KIZ DHX38 HJURP RGPD1 TMEM63B PACSIN3 IQGAP1 BMPR1A NDC80 MTCL1 HERC2 RGPD5 RGPD8 UACA LCK STRIP1 ZNF106 CEP131 PHF10	3.00e-05	1155	195	19	20360068
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	ABCF3 ACACA USP9X SPTBN1 PACSIN3 MCM7 IQGAP1 SAFB PELO SYNE2 UBE2E3 GOLGB1 PUF60 ANXA11 MYO18A DVL3 MUC5B GSN CST2 EPB41 CPSF7	3.07e-05	1367	195	21	32687490
Pubmed	Overexpression of myosin is associated with the development of uterine myoma.	MYH11 MYLK	3.13e-05	2	195	2	25181625
Pubmed	DGKζ ablation engenders upregulation of p53 level in the spleen upon whole-body ionizing radiation.	DGKZ TP53	3.13e-05	2	195	2	29079355
Pubmed	Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1.	WWP1 TP53	3.13e-05	2	195	2	16924229
Pubmed	The expression of p53-induced protein with death domain (Pidd) and apoptosis in oral squamous cell carcinoma.	PIDD1 TP53	3.13e-05	2	195	2	17437012
Pubmed	Cytoplasmic localization of DGKζ exerts a protective effect against p53-mediated cytotoxicity.	DGKZ TP53	3.13e-05	2	195	2	23606744
Pubmed	The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.	LCK HCK	3.13e-05	2	195	2	9705913
Pubmed	X-inactivation analysis of embryonic lethality in Ocrl wt/-; Inpp5b-/- mice.	INPP5B OCRL	3.13e-05	2	195	2	20195868
Pubmed	Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.	LCK HCK	3.13e-05	2	195	2	10364375
Pubmed	Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.	FBXO7 TP53	3.13e-05	2	195	2	21695055
Pubmed	Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice.	INPP5B OCRL	3.13e-05	2	195	2	9593760
Pubmed	Targeting mPGES-2 to protect against acute kidney injury via inhibition of ferroptosis dependent on p53.	PTGES2 TP53	3.13e-05	2	195	2	37907523
Pubmed	Phosphorylation of mammalian myosin light chain kinases by the catalytic subunit of cyclic AMP-dependent protein kinase and by cyclic GMP-dependent protein kinase.	MYLK PRKG2	3.13e-05	2	195	2	6547441
Pubmed	Identification of IQGAP1 as a SLC26A4 (Pendrin)-Binding Protein in the Kidney.	SLC26A4 IQGAP1	3.13e-05	2	195	2	35601831
Pubmed	IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.	IQGAP2 IQGAP1	3.13e-05	2	195	2	20977743
Pubmed	SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.	SAFB SAFB2	3.13e-05	2	195	2	19901029
Pubmed	Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis.	BMPR1A TP53	3.13e-05	2	195	2	25742798
Pubmed	Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.	IQGAP2 IQGAP1	3.13e-05	2	195	2	18180285
Pubmed	Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy.	INPP5B OCRL	3.13e-05	2	195	2	21183592
Pubmed	Low SAFB levels are associated with worse outcome in breast cancer patients.	SAFB SAFB2	3.13e-05	2	195	2	19137425
Pubmed	Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase.	INPP5B OCRL	3.13e-05	2	195	2	19700499
Pubmed	Identification of the Isoform-specific Interactions between the Tail and the Head of Class V Myosin.	MYO5A MYO5C	3.13e-05	2	195	2	26912658
Pubmed	Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells.	SAFB SAFB2	3.13e-05	2	195	2	26273616
Pubmed	Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1.	SAFB SAFB2	3.13e-05	2	195	2	26092125
Pubmed	Combined Loss of EAF2 and p53 Induces Prostate Carcinogenesis in Male Mice.	EAF2 TP53	3.13e-05	2	195	2	29029019
Pubmed	Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis?	SAFB SAFB2	3.13e-05	2	195	2	14587024
Pubmed	Regulation of p53 and NF-κB transactivation activities by DGKζ in catalytic activity-dependent and -independent manners.	DGKZ TP53	3.13e-05	2	195	2	33450306
Pubmed	HJURP regulates cellular senescence in human fibroblasts and endothelial cells via a p53-dependent pathway.	HJURP TP53	3.13e-05	2	195	2	23292286
Pubmed	Pendred Syndrome, or Not Pendred Syndrome? That Is the Question.	SLC26A4 MYO5C	3.13e-05	2	195	2	34680964
Pubmed	Genomic and proteomic profiles reveal the association of gelsolin to TP53 status and bladder cancer progression.	GSN TP53	3.13e-05	2	195	2	17982131
Pubmed	HIV-1 Nef disrupts membrane-microdomain-associated anterograde transport for plasma membrane delivery of selected Src family kinases.	LCK HCK	3.13e-05	2	195	2	23601552
Pubmed	LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients.	LCK PAX5	3.13e-05	2	195	2	25595912
Pubmed	Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.	HLA-DQB2 LCK	3.13e-05	2	195	2	22529380
Pubmed	Inhibiting mitochondrial respiration prevents cancer in a mouse model of Li-Fraumeni syndrome.	POLG TP53	3.13e-05	2	195	2	27869650
Pubmed	Kaposi's sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofactors RBM15 and OTT3 to promote expression of viral ORF59.	RBM15B RBM15	3.13e-05	2	195	2	21106733
Pubmed	Disrupted sperm function and fertilin beta processing in mice deficient in the inositol polyphosphate 5-phosphatase Inpp5b.	INPP5B OCRL	3.13e-05	2	195	2	11784089
Pubmed	Human myosin-Vc is a novel class V myosin expressed in epithelial cells.	MYO5A MYO5C	3.13e-05	2	195	2	11870218
Pubmed	Loss of GFAP expression in high-grade astrocytomas does not contribute to tumor development or progression.	GFAP TP53	3.13e-05	2	195	2	12776191
Pubmed	Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα.	SAFB SAFB2	3.13e-05	2	195	2	22566185
Pubmed	Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB x NZW)F1 mice.	LCK EPB41	3.13e-05	2	195	2	8171035
Pubmed	The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization.	HERC2 TP53	3.13e-05	2	195	2	24722987
Pubmed	Differential expression of IQGAP1/2 in Hepatocellular carcinoma and its relationship with clinical outcomes.	IQGAP2 IQGAP1	3.13e-05	2	195	2	24998570
Pubmed	Myosin Va is required for normal photoreceptor synaptic activity.	MYO5A MYO7A	3.13e-05	2	195	2	15316067
Pubmed	Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients.	PAX5 TP53	3.13e-05	2	195	2	22105368
Pubmed	OCRL-mutated fibroblasts from patients with Dent-2 disease exhibit INPP5B-independent phenotypic variability relatively to Lowe syndrome cells.	INPP5B OCRL	3.13e-05	2	195	2	25305077
Pubmed	Fv-2: identification and location of a second gene governing the spleen focus response to Friend leukemia virus in mice.	MYO5A MST1R	3.13e-05	2	195	2	5449211
Pubmed	Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy.	INPP5B OCRL	3.13e-05	2	195	2	27895154
Interaction	TJP2 interactions	ACACA DISC1 MCM7 EXOSC5 PGAM5 ZUP1 IQGAP1 SAFB CGN DNMBP WWP1 MYO18A DVL3 PARD3 EPB41	1.36e-07	288	194	15	int:TJP2
Interaction	DVL2 interactions	CWF19L2 ACACA EAF2 USP9X MCM7 PGAM5 IQGAP1 PKLR ATN1 EEF1AKMT3 WWP1 DVL3 WDR26 MST1R SNIP1 PARD3 HCK TP53 CPSF7	1.98e-06	557	194	19	int:DVL2
Interaction	AMOT interactions	USP9X DISC1 NDC80 CGN FBXO7 MTCL1 DNMBP WWP1 LCK PALS1 CEP131 PALS2 PARD3 NIN	2.12e-06	312	194	14	int:AMOT
Interaction	CHMP4B interactions	KIF18A MYH11 ACACA NBEAL1 USP9X SPTBN1 TMEM63B PACSIN3 PGAM5 GFAP IQGAP1 HERC2 GOLGB1 TRPV1 PUF60 PPP1R9A LCK GSN SAFB2 PALS2 TP53 CPSF7	2.13e-06	727	194	22	int:CHMP4B
Interaction	YAP1 interactions	MYH11 ACACA MYO1A HECW1 USP9X SPTBN1 APC2 TSPYL2 MCM7 PGAM5 GFAP IQGAP1 MYO3B PKLR IRS4 ATN1 UACA WWP1 DIDO1 GSN FRK PALS1 RNF2 RABEP1 PARD3 EPB41 TP53 CPSF7	2.22e-06	1095	194	28	int:YAP1
Interaction	FBXO25 interactions	MYH11 MYO1A MYO5A MCM7 GFAP NSRP1 IQGAP1 UBE2E3 UACA GSN PRKG2	3.59e-06	198	194	11	int:FBXO25
Interaction	CDC42 interactions	MYLK ACACA IQGAP2 USP9X SPTBN1 PACSIN3 WDR81 MCM7 URB2 CEMIP2 IQGAP1 BMPR1A SYNE2 CGN HERC2 MCF2L DNMBP PREX1 GOLGB1 ABCC1 FAM89A IRS4 PPP1R9A ANXA11 MYO18A MUC12 OCRL LCK CSPG4 PARD3 TP53	3.66e-06	1323	194	31	int:CDC42
Interaction	DHX40 interactions	CWF19L2 DHX38 NSRP1 SAFB FBXO7 RBM15 ZCCHC8 ZNF106 GPSM3 TP53 CPSF7 NIN	5.60e-06	249	194	12	int:DHX40
Interaction	IGFL3 interactions	MANBA LAMA1 ITGA7 JAG2 ADAMTS2 SNIP1 CEP131	7.85e-06	75	194	7	int:IGFL3
Interaction	CTTN interactions	MYLK MYO5A SPTBN1 NSRP1 MYO5C IQGAP1 NDC80 RBM15B RBM15 PPP1R9A MYO18A GSN STRIP1 SNIP1 CPSF7 NIN	7.88e-06	450	194	16	int:CTTN
Interaction	YWHAG interactions	DISC1 ACP2 SPTBN1 HJURP PGAM5 IQGAP1 FARP2 SYNE2 CGN RBM15B MTCL1 JAKMIP1 DNMBP HOMEZ RC3H2 RBM15 IRS4 UACA PUF60 MST1R SNIP1 ZNF106 RABEP1 GPSM3 CEP131 R3HDM1 PARD3 EPB41 TP53	9.21e-06	1248	194	29	int:YWHAG
Interaction	GAGE5 interactions	MYO5A NSRP1 MYO5C UACA DIDO1 SNIP1	1.04e-05	52	194	6	int:GAGE5
Interaction	UQCR11 interactions	NSRP1 RBM15B PTGES2 DIDO1 SNIP1 SAFB2	1.16e-05	53	194	6	int:UQCR11
Interaction	ARRDC3 interactions	IQGAP2 USP9X MCM7 FARP2 BMPR1A RBM15B UBE2E3 RBM15 ZCCHC8 WWP1 PARD3	1.16e-05	224	194	11	int:ARRDC3
Interaction	PECR interactions	ACOX1 ZUP1 UBE2E3 CPE TP53	1.28e-05	32	194	5	int:PECR
Interaction	SAA1 interactions	LAMA1 SAFB PPP1R9A DIDO1 SNIP1 SAFB2	1.30e-05	54	194	6	int:SAA1
Interaction	PSENEN interactions	DHX38 NSRP1 RBM15B DIDO1 SNIP1 SAFB2 PARD3	1.31e-05	81	194	7	int:PSENEN
Interaction	LIMA1 interactions	MYO5A DISC1 SPTBN1 PACSIN3 PGAM5 MYO5C IQGAP1 CGN TRPV1 ZCCHC8 PPP1R9A MYO18A GSN RNF2 TP53	1.86e-05	429	194	15	int:LIMA1
Interaction	YWHAH interactions	MYH11 SPTBN1 DHX38 HJURP IQGAP1 SYNE2 CGN RBM15B MTCL1 JAKMIP1 DNMBP HOMEZ RBM15 IRS4 UACA ZCCHC8 WDR26 MST1R ZNF106 RABEP1 GPSM3 CEP131 R3HDM1 PARD3 EPB41 NIN	2.17e-05	1102	194	26	int:YWHAH
Interaction	YWHAZ interactions	MYH11 MYO5A DISC1 SPTBN1 HJURP GFAP SYNE2 CGN JAKMIP1 HERC2 DNMBP HOMEZ RBM15 IRS4 UACA PUF60 MYO18A ARHGEF18 LCK GSN MST1R RABEP1 GPSM3 CEP131 R3HDM1 PARD3 EPB41 TP53 NIN	2.59e-05	1319	194	29	int:YWHAZ
Interaction	MAD2L1BP interactions	SLC26A4 ZNF202 ZSCAN29 DNMBP HOMEZ TP53	2.63e-05	61	194	6	int:MAD2L1BP
Interaction	EXOSC9 interactions	EXOSC5 FBXW8 PELO ZCCHC8 MST1R ZNF106 PALS2 PHF10 TP53	2.81e-05	162	194	9	int:EXOSC9
Interaction	NEXN interactions	DISC1 MYO5C IQGAP1 TRPV1 PPP1R9A MYO18A GSN	2.81e-05	91	194	7	int:NEXN
Interaction	KIF20A interactions	MYH11 MYO1A INPP5B SPTBN1 APC2 PACSIN3 PGAM5 GFAP SAFB MYO3B SYNE2 CGN HERC2 RGPD8 UACA PUF60 PPP1R9A MYO18A DIDO1 ZNF106 RNF2 RABEP1 SAFB2 PARD3 TP53	2.82e-05	1052	194	25	int:KIF20A
Interaction	MYO5A interactions	MYH11 MYLK MYO5A SPTBN1 GFAP MYO5C IQGAP1 PEX3 MYO18A LCK	2.96e-05	204	194	10	int:MYO5A
Interaction	FXR1 interactions	CWF19L2 USP9X HLA-DRB5 APC2 GFAP MAPK8IP3 KAZN JAKMIP1 HERC2 GOLGB1 RC3H2 ATN1 DIDO1 OCRL SAFB2 GPSM3 R3HDM1 HCK TP53	3.24e-05	679	194	19	int:FXR1
Interaction	ANAPC15 interactions	DHX38 NSRP1 SAFB RBM15B PPP1R9A DIDO1 SNIP1 SAFB2	3.41e-05	128	194	8	int:ANAPC15
Interaction	NXF1 interactions	ABCF3 EFCAB11 ACACA DISC1 SPTBN1 DHX38 HJURP RGPD1 WDR81 MCM7 GFAP IQGAP1 ZSCAN29 NDC80 RBM15B MTCL1 HOMEZ RGPD5 RBM15 PEX3 MYO18A DVL3 OCRL STRIP1 TMED3 ZNF106 NANS TP53 CPSF7	3.69e-05	1345	194	29	int:NXF1
Interaction	IFI27L1 interactions	NSRP1 SAFB RBM15B DIDO1 SNIP1 SAFB2	3.79e-05	65	194	6	int:IFI27L1
Interaction	RAB35 interactions	IQGAP2 MYO5A SPTBN1 CEMIP2 IQGAP1 JAG2 SYNE2 GOLGB1 ABCC1 TRPV1 IRS4 UACA PPP1R9A OCRL PALS1 PARD3 EPB41	4.17e-05	573	194	17	int:RAB35
Interaction	CASQ2 interactions	MYO5A FBXW8 FBXO7 OXSM PPP1R9A NIN	4.51e-05	67	194	6	int:CASQ2
Interaction	C11orf52 interactions	IQGAP2 SPTBN1 CEMIP2 IQGAP1 FARP2 JAG2 ABCC1 IRS4 UACA PALS2 PARD3 EPB41	5.08e-05	311	194	12	int:C11orf52
Interaction	NDC80 interactions	KIZ PGAM5 NSRP1 MYO5C NDC80 SYNE2 MTCL1 HERC2 UACA CEP131 CPSF7 NIN	5.24e-05	312	194	12	int:NDC80
Interaction	UACA interactions	MYLK ZUP1 NDC80 TRPV1 UACA RNF2 RABEP1 PARD3	5.25e-05	136	194	8	int:UACA
Interaction	PTPN14 interactions	USP9X RHPN1 CRLF3 CGN RC3H2 WWP1 LCK WDR26 PARD3	5.61e-05	177	194	9	int:PTPN14
Interaction	WWTR1 interactions	MCM7 PGAM5 CGN RGPD5 IRS4 PUF60 DVL3 DIDO1 PALS1 MTRF1 RABEP1 PARD3 EPB41 TP53	6.25e-05	422	194	14	int:WWTR1
Interaction	UBE2D2 interactions	HECW1 USP9X ACOX1 FBXO7 HERC2 UBR2 RC3H2 WWP1 DVL3 RNF2 PDZRN3 TP53	6.29e-05	318	194	12	int:UBE2D2
Interaction	MATR3 interactions	ACACA USP9X DISC1 ZUP1 IQGAP1 SAFB FBXO7 RBM15B HERC2 RC3H2 PUF60 ZCCHC8 WWP1 SNIP1 ZNF106 RNF2 SAFB2 TP53	6.63e-05	655	194	18	int:MATR3
Interaction	EPHA2 interactions	ACACA PDK1 PACSIN3 ITGA7 CEMIP2 FARP2 PKLR GOLGB1 ABCC1 IRS4 UACA PPP1R9A OCRL LCK PALS1 PALS2 PARD3 HCK TP53	6.96e-05	719	194	19	int:EPHA2
Interaction	KHDRBS1 interactions	MYO7A DISC1 MATN2 DHX38 PACSIN3 DNMBP RC3H2 RBM15 LCK FRK RNF2 PALS2 HCK	7.00e-05	373	194	13	int:KHDRBS1
Interaction	CCDC88B interactions	CWF19L2 EXOSC5 CCDC88B TSGA10IP HCK	7.02e-05	45	194	5	int:CCDC88B
Interaction	CAPZA2 interactions	MYO5A SPTBN1 PACSIN3 MYO5C IQGAP1 CGN MTCL1 RC3H2 PPP1R9A MYO18A GSN MST1R FRK ZNF106	7.64e-05	430	194	14	int:CAPZA2
Interaction	PEX14 interactions	IQGAP2 ACOX1 MYO5C IQGAP1 SYNE2 PEX3 OCRL RABEP1 CEP131 STK38L	1.04e-04	237	194	10	int:PEX14
Interaction	SYNPO interactions	MYO5A SPTBN1 PACSIN3 MYO5C IQGAP1 CGN PPP1R9A MYO18A GSN	1.05e-04	192	194	9	int:SYNPO
Interaction	SIRT7 interactions	ACACA MYO5A USP9X SPTBN1 DHX38 MCM7 URB2 PGAM5 IQGAP1 SYNE2 CGN HERC2 RBM15 IRS4 PUF60 ZCCHC8 ANXA11 DIDO1 TP53	1.09e-04	744	194	19	int:SIRT7
Interaction	AMOTL2 interactions	USP9X NDC80 FBXO7 TSGA10IP WWP1 MKNK1 PALS1 PARD3	1.10e-04	151	194	8	int:AMOTL2
Interaction	SSX2IP interactions	EAF2 ZNF202 MCM7 NDC80 HERC2 TSGA10IP DVL3 OCRL CEP131 TP53 NIN	1.15e-04	288	194	11	int:SSX2IP
Interaction	SKAP2 interactions	FBXO7 IRS4 LCK FRK HCK	1.29e-04	51	194	5	int:SKAP2
Interaction	ECT2 interactions	CWF19L2 MYH11 MYO1A USP9X SPTBN1 PACSIN3 PGAM5 GFAP NSRP1 MYO5C IQGAP1 PELO EXOC3L4 DNAH9 PUF60 PPP1R9A MYO18A GSN PARD3 TP53 CPSF7	1.35e-04	887	194	21	int:ECT2
Interaction	RHOD interactions	MYO5A USP9X SPTBN1 PACSIN3 CEMIP2 IQGAP1 JAG2 SYNE2 GOLGB1 ABCC1 IRS4 PPP1R9A MYO18A OCRL PARD3 EPB41	1.39e-04	572	194	16	int:RHOD
Interaction	RICTOR interactions	HK2 MYO5A USP9X SPTBN1 RGPD1 NSRP1 ZUP1 IQGAP1 PELO PREX1 RGPD5 RGPD8 EEF1AKMT3 MYO18A LCK GSN RNF2 NANS EPB41	1.41e-04	759	194	19	int:RICTOR
Interaction	MIB1 interactions	USP9X MCM7 PGAM5 JAG2 NDC80 IRS4 RGPD8 ZCCHC8 CEP131 TP53 NIN	1.41e-04	295	194	11	int:MIB1
Interaction	TRIM27 interactions	CWF19L2 ABCF3 DISC1 RGPD1 MCM7 GFAP ZSCAN29 RHPN1 TSGA10IP UBE2E3 GOLGB1 RNF2 STK38L HCK TP53	1.43e-04	514	194	15	int:TRIM27
Interaction	WDR3 interactions	MYH11 EXOSC5 IQGAP1 RC3H2 SNIP1 EPB41 TP53 NIN	1.64e-04	160	194	8	int:WDR3
Interaction	TMOD1 interactions	MYO5C IQGAP1 GOLGB1 MYO18A GSN CEP131 EPB41 NIN	1.71e-04	161	194	8	int:TMOD1
Interaction	LRRC31 interactions	MYH11 ACACA MYO5A MYO5C IQGAP1 HERC2 UACA MYO18A TP53	1.72e-04	205	194	9	int:LRRC31
Interaction	YWHAQ interactions	MYH11 ACACA PDK1 DISC1 HJURP IQGAP1 BMPR1A FBXW8 CGN DNMBP GOLGB1 HOMEZ IRS4 UACA WWP1 LCK MST1R ZNF106 RABEP1 GPSM3 CEP131 R3HDM1 PARD3 EPB41	1.96e-04	1118	194	24	int:YWHAQ
Interaction	TTC3 interactions	KIF18A SPTBN1 FBXO7 HERC2 UBE2E3 POLG WHAMM	2.00e-04	124	194	7	int:TTC3
Interaction	DBN1 interactions	MYO5A DISC1 SPTBN1 PACSIN3 MYO5C IQGAP1 CGN HERC2 DNMBP PPP1R9A MYO18A GSN TP53	2.11e-04	417	194	13	int:DBN1
Interaction	CCDC8 interactions	MYO5A USP9X PACSIN3 MCM7 PGAM5 MYO5C IQGAP1 FBXW8 CGN HERC2 GOLGB1 IRS4 PPP1R9A ANXA11 LCK CEP131 TP53	2.13e-04	656	194	17	int:CCDC8
Interaction	MYO5C interactions	MYO5A SPTBN1 MYO5C IQGAP1 NDC80 CGN MYO18A TP53	2.28e-04	168	194	8	int:MYO5C
Interaction	INTS4P2 interactions	MYO5A GFAP MYO18A	2.34e-04	13	194	3	int:INTS4P2
Interaction	LRRCC1 interactions	NDC80 STRIP1 CEP131 NIN	2.42e-04	32	194	4	int:LRRCC1
Interaction	PDLIM7 interactions	MYO5A SPTBN1 RGPD1 GFAP MYO5C IQGAP1 TSGA10IP WWP1 PARD3 TP53	2.50e-04	264	194	10	int:PDLIM7
Interaction	CALD1 interactions	DISC1 SPTBN1 MYO5C CGN PPP1R9A ANXA11 MYO18A MST1R PALS1 TP53	2.58e-04	265	194	10	int:CALD1
Interaction	EZH1 interactions	DHX38 NSRP1 RBM15B DIDO1 SNIP1 SAFB2	2.64e-04	92	194	6	int:EZH1
Interaction	ACTA1 interactions	MYLK MYO7A APC2 IQGAP1 CRLF3 DNMBP RC3H2 MYO18A GSN MTRF1 EPB41 TP53	2.65e-04	371	194	12	int:ACTA1
Interaction	TFIP11 interactions	CWF19L2 EAF2 DISC1 KIZ MCM7 EXOSC5 GFAP IQGAP1 NDC80 HERC2 TSGA10IP TP53 CPSF7	2.66e-04	427	194	13	int:TFIP11
Interaction	SHMT2 interactions	MYLK ACACA PDK1 DHX38 HJURP WDR81 ZUP1 BMPR1A DNAJC28 NDC80 FBXO7 PREX1 MYO18A STRIP1 MTRF1 NANS CPSF7	2.78e-04	671	194	17	int:SHMT2
Interaction	BIVM interactions	SAFB HOMEZ SAFB2	2.96e-04	14	194	3	int:BIVM
Interaction	WWC1 interactions	MYO5A USP9X FARP2 RHPN1 PALS1 EPB41	2.97e-04	94	194	6	int:WWC1
Interaction	LINC02910 interactions	NSRP1 SAFB RBM15B DIDO1 SNIP1 SAFB2	3.15e-04	95	194	6	int:LINC02910
Interaction	YWHAB interactions	SPTBN1 HJURP IQGAP1 CGN MTCL1 JAKMIP1 DNMBP HOMEZ RC3H2 IRS4 UACA ZCCHC8 MST1R ZNF106 RABEP1 GPSM3 CEP131 R3HDM1 PARD3 STK38L EPB41 TP53	3.18e-04	1014	194	22	int:YWHAB
Interaction	MARK2 interactions	FBXO7 MTCL1 JAKMIP1 HERC2 RC3H2 TRPV1 DVL3 LCK GPSM3 PARD3	3.36e-04	274	194	10	int:MARK2
Interaction	CEP63 interactions	CWF19L2 DISC1 SPTBN1 RGPD1 NDC80 TSGA10IP CEP131 NIN	3.51e-04	179	194	8	int:CEP63
Interaction	CDK9 interactions	ACACA MYO5A SPTBN1 EXOSC5 NSRP1 IQGAP1 BMPR1A SAFB PELO NDC80 RBM15B MYO18A OCRL GSN HCK TP53 CPSF7	3.52e-04	685	194	17	int:CDK9
Interaction	OCLN interactions	IQGAP2 SPTBN1 CEMIP2 JAG2 CGN GOLGB1 ABCC1 IRS4 UACA PPP1R9A OCRL LCK PARD3 EPB41	3.62e-04	500	194	14	int:OCLN
Interaction	CPAP interactions	NDC80 FBXO7 ATN1 DVL3 CEP131 EPB41 TP53 NIN	3.92e-04	182	194	8	int:CPAP
Interaction	DVL3 interactions	MATN2 RBM15B KAZN HOMEZ WWP1 DVL3 DIDO1 MST1R SNIP1 PDZRN3	3.99e-04	280	194	10	int:DVL3
Interaction	TPCN2 interactions	ACP2 BMPR1A TPCN2 OCRL TP53	4.06e-04	65	194	5	int:TPCN2
Interaction	NXF2 interactions	RGPD5 RGPD8 DVL3 ZNF106 CEP131	4.06e-04	65	194	5	int:NXF2
Interaction	PXN interactions	PGAM5 IQGAP1 PKLR DNMBP GOLGB1 LCK GSN CEP131 HCK TP53 NIN	4.10e-04	334	194	11	int:PXN
Interaction	CLTB interactions	SPTBN1 MYO5C IQGAP1 DNMBP TRPV1 MYO18A OCRL TP53	4.37e-04	185	194	8	int:CLTB
Interaction	LNX1 interactions	USP9X CLK4 TSPYL2 CCDC88B IQGAP1 NDC80 CGN KAZN HOMEZ WWP1 DVL3 LRRC3B TEKT4 PDZRN3 TP53 CPSF7	4.39e-04	634	194	16	int:LNX1
Interaction	RUNDC1 interactions	ACACA EEF1AKMT3 TP53	4.48e-04	16	194	3	int:RUNDC1
Interaction	YWHAE interactions	MYH11 DISC1 HLA-DRB3 HLA-DRB5 HJURP PGAM5 IQGAP1 CGN JAKMIP1 DNMBP UBR2 RC3H2 RBM15 IRS4 MST1R ZNF106 RABEP1 GPSM3 CEP131 R3HDM1 PARD3 STK38L EPB41 TP53 NIN	4.49e-04	1256	194	25	int:YWHAE
Interaction	MAPK9 interactions	LAMA1 GFAP MAPK8IP3 RHPN1 FBXO7 EEF2K PAX5 TP53	4.53e-04	186	194	8	int:MAPK9
Interaction	RHOH interactions	MYO5A USP9X SPTBN1 PACSIN3 CEMIP2 PREX1 GOLGB1 ABCC1 IRS4 UACA MYO18A OCRL LCK PARD3	4.58e-04	512	194	14	int:RHOH
Interaction	LZTS2 interactions	CWF19L2 EXOSC5 GFAP IQGAP1 RHPN1 CGN KAZN DNMBP RBM15 MYO18A LCK CEP131 PARD3 TP53	4.58e-04	512	194	14	int:LZTS2
Interaction	CDH1 interactions	ABCF3 MYO7A USP9X SPTBN1 CEMIP2 IQGAP1 FARP2 CGN GOLGB1 UACA PUF60 DVL3 RNF2 NANS PARD3 CCDC65 PCDHGC3 EPB41	4.67e-04	768	194	18	int:CDH1
Interaction	HSP90AA1 interactions	HK2 ACP2 HLA-DRB3 SPTBN1 HLA-DRB5 BMPR1A FBXW8 MYO3B FBXO7 RC3H2 TRPV1 IRS4 EEF1AKMT3 WWP1 DIDO1 LCK GSN MST1R FRK NANS WDR87 PRKG2 STK38L HCK TP53	4.87e-04	1263	194	25	int:HSP90AA1
Interaction	SEPTIN10 interactions	HK2 MYO5C DNMBP GOLGB1 DVL3 CEP131 NIN	4.98e-04	144	194	7	int:SEPTIN10
Interaction	RHOB interactions	IQGAP2 USP9X SPTBN1 PACSIN3 CEMIP2 IQGAP1 JAG2 BMPR1A UBR2 ABCC1 IRS4 UACA PPP1R9A MYO18A ARHGEF18 OCRL PALS1 MTRF1 PARD3	5.01e-04	840	194	19	int:RHOB
Interaction	LATS2 interactions	IQGAP2 USP9X CGN RBM15 FRK PALS1 CEP131 PARD3 TP53 NIN	5.11e-04	289	194	10	int:LATS2
Interaction	CALM3 interactions	ARPP21 SPTBN1 MYO5C IQGAP1 RC3H2 PPP1R9A MYO18A DIDO1 MST1R PALS1 CEP131	5.12e-04	343	194	11	int:CALM3
GeneFamily	PDZ domain containing	RHPN1 PREX1 CARD14 PPP1R9A MYO18A DVL3 PALS1 PALS2 PARD3 PDZRN3	1.70e-07	152	132	10	1220
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	FARP2 MCF2L DNMBP PREX1 ARHGEF18	1.20e-04	66	132	5	722
GeneFamily	Myosins, class V	MYO5A MYO5C	1.58e-04	3	132	2	1100
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	CARD14 PALS1 PALS2	8.75e-04	26	132	3	904
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 WDR81	1.84e-03	9	132	2	1230
Coexpression	GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP	ZNF394 SYNE2 ZBTB40 GOLGB1 TRPV1 WHAMM ARHGEF18 ENTPD4 GSN	1.58e-05	195	194	9	M7397
Coexpression	GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN	EAF2 IQGAP2 DCSTAMP KLHL21 KAZN CARD14 FAM89A TMED3 NANS	1.71e-05	197	194	9	M9700
Coexpression	GSE3982_DC_VS_NKCELL_DN	HECW1 SPTBN1 TSPYL2 MYO5C ZNF394 SYNE2 DVL3 ARHGEF18 DIDO1	1.71e-05	197	194	9	M5480
Coexpression	GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN	SAFB KLHL21 CRLF3 ANXA11 HID1 PCED1B NARF EPB41 TP53	1.93e-05	200	194	9	M7436
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL1 SPTBN1 IQGAP1 SYNE2 GOLGB1 LCORL WWP1 PPP1R9A FRK ZNF106 R3HDM1	8.46e-10	191	194	11	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL1 SPTBN1 IQGAP1 SYNE2 GOLGB1 LCORL WWP1 PPP1R9A FRK ZNF106 R3HDM1	8.46e-10	191	194	11	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL1 SPTBN1 IQGAP1 SYNE2 LCORL WWP1 PPP1R9A FRK ZNF106 R3HDM1	1.26e-08	191	194	10	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IQGAP2 TSPYL2 CEMIP2 SYNE2 ABCD2 WWP1 DGKZ GPSM3 EPB41	1.40e-07	187	194	9	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GIMAP4 MYH11 MYLK SLC26A4 SPTBN1 GOLGB1 ADAMTS2 WDR26 NIN	1.60e-07	190	194	9	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GIMAP4 SPTBN1 SYNE2 MCF2L UACA PPP1R9A DGKZ HID1 NIN	2.48e-07	200	194	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EAF2 IQGAP2 MYO5A MYO7A DISC1 HLA-DRB5 MKNK1 HCK	1.71e-06	187	194	8	39b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IQGAP2 SPTBN1 CEMIP2 SYNE2 PREX1 GOLGB1 LCK NIN	1.92e-06	190	194	8	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDK1 TSPYL2 SYNE2 RGPD5 WWP1 WHAMM LCK PCED1B	2.00e-06	191	194	8	696921a4f160b6b55698652488ed781e855e5e51
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK ITGA7 IRS4 CPE CSPG4 PRKG2 STK38L	2.00e-06	191	194	8	8e8beb8e8a3b33cac83d3f7ce915a71e3654fdab
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 MYLK ITGA7 BMPR1A ADAMTS2 CPE GSN CSPG4	2.08e-06	192	194	8	26d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCell	368C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MYH11 MYLK ITGA7 SYNE2 MCF2L FRY CSPG4 STK38L	2.16e-06	193	194	8	5260ac95a15cc43a19909badad0c7e3854da920d
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 MYLK ITGA7 BMPR1A ADAMTS2 CPE GSN CSPG4	2.16e-06	193	194	8	7fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCell	Immune-interstitial_macrophage_(C1Q_positive)\|World / Lineage, Cell type, age group and donor	IQGAP2 MYO5A MYO7A DISC1 PREX1 WWP1 MKNK1 HCK	2.16e-06	193	194	8	64d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCell	368C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	MYH11 MYLK ITGA7 SYNE2 MCF2L FRY CSPG4 STK38L	2.16e-06	193	194	8	5ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MYH11 ITGA7 CPE FRK FRY CSPG4 CST2 PRKG2	2.16e-06	193	194	8	360079cbaa18b74e4a48c5de40844faca076e1a6
ToppCell	Leuk-UTI\|World / Disease, Lineage and Cell Type	GIMAP4 EPSTI1 NBEAL1 HLA-DQB2 ACP2 HLA-DRB5 RAB24 HCK	2.16e-06	193	194	8	26119a0b5d7684022fd16b8b73a0ef5a7d70f3d1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CWF19L2 TSPYL2 CEMIP2 SYNE2 RGPD5 LCK PCED1B PAX5	2.61e-06	198	194	8	a3bd099ef0e606c2da690a6fcf6f79e9360c9c9f
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SPTBN1 CEMIP2 IQGAP1 SYNE2 UACA FRY PARD3 PDZRN3	2.81e-06	200	194	8	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SPTBN1 CEMIP2 IQGAP1 SYNE2 UACA FRY PARD3 PDZRN3	2.81e-06	200	194	8	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Severe / Disease, condition lineage and cell class	GIMAP4 EPSTI1 TRANK1 SYNE2 ABCD2 LCK PCED1B EPB41	2.81e-06	200	194	8	deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SPTBN1 CEMIP2 IQGAP1 SYNE2 UACA FRY PARD3 PDZRN3	2.81e-06	200	194	8	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	NBEAL1 MATN2 ITGA7 GFAP IQGAP1 UACA GSN ZNF106	2.81e-06	200	194	8	5ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	LAMA1 ITGA7 ABCD2 CPE LRRC3B PARD3 GRAMD1C PDZRN3	2.81e-06	200	194	8	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SPTBN1 CEMIP2 IQGAP1 SYNE2 UACA FRY PARD3 PDZRN3	2.81e-06	200	194	8	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SPTBN1 CEMIP2 IQGAP1 SYNE2 UACA FRY PARD3 PDZRN3	2.81e-06	200	194	8	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	SPTBN1 CEMIP2 IQGAP1 SYNE2 UACA FRY PARD3 PDZRN3	2.81e-06	200	194	8	7136936d05ab344a560cf159684c881063b5430d
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIZ HJURP TSPYL2 URB2 JAKMIP1 LCK PCED1B	6.38e-06	159	194	7	03d77e7fee40262bf0942aab96b273f1c4f5d8e3
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D122\|Adult / Lineage, Cell type, age group and donor	IQGAP2 MYO5A MYO7A DISC1 PREX1 ADAMTS2 MKNK1	8.46e-06	166	194	7	be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell	Immune_cells\|World / Lineage and Cell class	GIMAP4 EPSTI1 JAKMIP1 LCK GPSM3 PAX5 HCK	8.46e-06	166	194	7	f20b58528749ee88fba3ccdaf3f3fa0d06cb9a91
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPTBN1 CEMIP2 EXOC3L4 SYNE2 WHAMM FRK EPB41	8.80e-06	167	194	7	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARPP21 JAG2 MYO3B RBM15B TPCN2 ADAMTS3 ENTPD4	9.88e-06	170	194	7	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPSTI1 PDK1 HJURP MCM7 NDC80 JAKMIP1 LCK	1.03e-05	171	194	7	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK ITGA7 PELO CARD14 FRK CSPG4	1.11e-05	173	194	7	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	EAF2 HLA-DQB2 HLA-DRB5 CEMIP2 MYO5C PAX5 PALS2	1.11e-05	173	194	7	f135cc9dcf34f33ced3210171ab40ae6d77cfae0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK ITGA7 PELO CARD14 FRK CSPG4	1.11e-05	173	194	7	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	EAF2 HLA-DQB2 HLA-DRB5 CEMIP2 MYO5C PAX5 PALS2	1.11e-05	173	194	7	23248019c819f6e38337dcc4edb763ef1992e89e
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH11 MYLK PACSIN3 ITGA7 CPE FRY CSPG4	1.24e-05	176	194	7	90f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARPP21 IQGAP2 HLA-DQB2 HLA-DRB5 CCDC88B HCK NIN	1.28e-05	177	194	7	c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 EPSTI1 PDK1 NDC80 CRLF3 ARHGEF18 LCK	1.33e-05	178	194	7	a9a8567d8fdc0fffd612fee16b5b29ef7b1c9307
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 EPSTI1 PDK1 NDC80 CRLF3 ARHGEF18 LCK	1.33e-05	178	194	7	5ecbea15efd304057aef826ec2f385997bfaf0c9
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK INPP5B ITGA7 FRY CSPG4 PRKG2	1.38e-05	179	194	7	8da6863edc756540bb097cc7221c1408640d9bb4
ToppCell	ASK452-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	KIF18A INPP5B MATN2 SLC26A4 FARP2 DNAH9 OCRL	1.38e-05	179	194	7	c3cf49c069e66db16d2fce1de4c52a4c4fe7e832
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK INPP5B ITGA7 FRY CSPG4 PRKG2	1.38e-05	179	194	7	f39c13c99a07d009cc677e363ffe089089c64916
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MYH11 KIZ CEMIP2 KAZN ABCD2 ABCC1 FRY	1.38e-05	179	194	7	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CEMIP2 NDC80 SYNE2 JAKMIP1 CPE LCK EPB41	1.43e-05	180	194	7	6bb9f41c3a99d1bbe697f589fb2bcea9b7bfbeee
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK HECW1 ITGA7 ABCD2 CSPG4 PRKG2	1.43e-05	180	194	7	0059e5acade6c895fd629767bea1c15f40b0d1b0
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	HLA-DQB2 ACOX1 HLA-DRB5 CDH20 GSN MKNK1 HCK	1.43e-05	180	194	7	289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK HECW1 ITGA7 ABCD2 CSPG4 PRKG2	1.43e-05	180	194	7	dfb8412e1e06fa7349e66eea2ef27d9ea98b7893
ToppCell	facs-Heart-LV-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A EAF2 CRLF3 MYO18A ARHGEF18 SAFB2 PAX5	1.54e-05	182	194	7	6dff753d65ba45db81f3cc0c9f59e1779d490955
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIMAP4 EPSTI1 PDK1 NDC80 CRLF3 LCK PCED1B	1.59e-05	183	194	7	c9cb69377883d4579c608ec8b265153fe5290e67
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	MYH11 MYLK NBEAL1 CPE PCED1B FRY STK38L	1.59e-05	183	194	7	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	nucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EPSTI1 RGPD1 CEMIP2 NDC80 JAKMIP1 ABCC1 LCK	1.71e-05	185	194	7	a86a3a1a187a4d8d7762bc6d3dcb22c982178d22
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP4 SPTBN1 MYO5C JAG2 RHPN1 PREX1 UACA	1.83e-05	187	194	7	25efb82afe863a853ecdd781ad89026c993aaa67
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	MYH11 MYLK NBEAL1 PCED1B FRY STK38L PDZRN3	1.89e-05	188	194	7	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MYO5C MYO3B CGN PPP1R9A FRY LRRC3B PRKG2	1.89e-05	188	194	7	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IQGAP2 DISC1 SYNE2 JAKMIP1 ABCC1 LCK EPB41	1.96e-05	189	194	7	df30478b288084a1bd48f660409dcc784040897c
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK PACSIN3 ITGA7 MTCL1 CSPG4 PRKG2	1.96e-05	189	194	7	de51fbd6fdb24fc4549393cf41a020005444b2aa
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HJURP MYO5C MYO3B CGN PPP1R9A HID1 TEKT4	1.96e-05	189	194	7	c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|368C / Donor, Lineage, Cell class and subclass (all cells)	IQGAP2 MYO5A MYO7A HLA-DQB2 HLA-DRB5 GSN HCK	2.03e-05	190	194	7	cbba3d94a4c3e0b0d14f3b7c60dba5d6e097c5e3
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK PACSIN3 ITGA7 MTCL1 CSPG4 PRKG2	2.03e-05	190	194	7	1d8e169d2448a34180c415843bb49aa45ed540c5
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IQGAP2 MYO5A MYO7A DISC1 HLA-DRB5 DNMBP ADAMTS2	2.03e-05	190	194	7	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	IPF-Lymphoid-T\|IPF / Disease state, Lineage and Cell class	IQGAP2 TSPYL2 CEMIP2 SYNE2 JAKMIP1 ABCC1 LCK	2.03e-05	190	194	7	d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK ITGA7 IRS4 CPE CSPG4 PRKG2	2.10e-05	191	194	7	60bc1f3efa7bbad5cb7944fe5e049ea79cd1745a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDK1 TSPYL2 SYNE2 RGPD5 WHAMM LCK PCED1B	2.10e-05	191	194	7	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MYH11 ITGA7 CPE FRK CSPG4 CST2 PRKG2	2.17e-05	192	194	7	a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 MANBA USP9X CEMIP2 HERC2 UBR2 MYO18A	2.17e-05	192	194	7	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	Control-Lymphoid-T\|Control / Disease state, Lineage and Cell class	IQGAP2 TSPYL2 CEMIP2 SYNE2 JAKMIP1 ABCC1 LCK	2.24e-05	193	194	7	af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 MYLK ITGA7 BMPR1A CPE GSN CSPG4	2.24e-05	193	194	7	88916d9a7d831eb52848599917c04238f8f9812b
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Severe / Disease group, lineage and cell class	GIMAP4 EPSTI1 SYNE2 ABCD2 LCK PCED1B EPB41	2.24e-05	193	194	7	beb862d38b88572836b0a797c8efef7a2492e0b9
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GIMAP4 EPSTI1 SYNE2 ABCD2 LCK PCED1B EPB41	2.24e-05	193	194	7	f4310faa13fc8ce99a217e2d1c9cc733683797a1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GIMAP4 EPSTI1 SYNE2 ABCD2 LCK PCED1B EPB41	2.24e-05	193	194	7	089aece40130034a89a5213be778f10b0787eeba
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GIMAP4 EPSTI1 SYNE2 ABCD2 LCK PCED1B EPB41	2.24e-05	193	194	7	2901d7a9672a8cf70c9f1c752685b45e4d79ac70
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GIMAP4 EPSTI1 SYNE2 ABCD2 LCK PCED1B EPB41	2.24e-05	193	194	7	f8af695457d2a0a911a5ac491742465864ebda37
ToppCell	nucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IQGAP2 TSPYL2 CEMIP2 SYNE2 JAKMIP1 ABCC1 LCK	2.24e-05	193	194	7	9c9434a3297b85774b4f0ecab6294f44d738e29f
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK PACSIN3 ITGA7 CPE CSPG4 STK38L	2.32e-05	194	194	7	b8a130ffae68ffe550bf335460a1ec1035cf8d8d
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH11 MYLK PACSIN3 ITGA7 CPE FRY CSPG4	2.40e-05	195	194	7	b21bf50d689fc3b933182f4bfdde82f375257b72
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH11 MYLK PACSIN3 ITGA7 CPE FRY CSPG4	2.40e-05	195	194	7	b5db3c0e3a41f68fca18e0a74e1b7e81df4f94c5
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	GIMAP4 SPTBN1 TRANK1 SYNE2 WWP1 LCK EPB41	2.40e-05	195	194	7	22191d361af136942508f1553ff41a626ed982ad
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH11 MYLK PACSIN3 ITGA7 CPE CSPG4 STK38L	2.40e-05	195	194	7	0bdf845939bc4b8cc94f2808aea60f818425b076
ToppCell	Epithelial-A_(AT1)\|World / shred on cell class and cell subclass (v4)	NBEAL1 SPTBN1 TMEM63B TINAG CGN WWP1 PALS1	2.48e-05	196	194	7	484bbc6b1f58bc260964babb949d14f5df101393
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 MYLK MATN2 ITGA7 UACA ADAMTS2 PDZRN3	2.48e-05	196	194	7	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH11 MYLK MATN2 ITGA7 UACA ADAMTS2 PDZRN3	2.48e-05	196	194	7	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	mild-Treg\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EPSTI1 SYNE2 JAKMIP1 WWP1 LCK PCED1B EPB41	2.56e-05	197	194	7	39800e6e83f2d333b753d121c7aeb2912b91faa2
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYLK ITGA7 PELO UACA ADAMTS2 CPE CSPG4	2.56e-05	197	194	7	452be45f4aac8459dd860493171f5f715368d663
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYH11 MYLK MATN2 LAMA1 JAG2 MTCL1 PCED1B	2.56e-05	197	194	7	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	mild-dn_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HECW1 EPSTI1 SPTBN1 TRANK1 SYNE2 ZBTB40 LCK	2.56e-05	197	194	7	07a1f59c83b748825e0708cd1cc7b63a2cb856cc
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH11 MYLK ADAMTS2 CPE GSN CSPG4 PDZRN3	2.56e-05	197	194	7	8c728cd3c0382c4f3e4b78647b6e1447bb40ace1
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CWF19L2 TSPYL2 SYNE2 GOLGB1 RGPD5 UBR2 EPB41	2.73e-05	199	194	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Sepsis-Leuk-UTI-Myeloid-tDC\|Leuk-UTI / Disease, condition lineage and cell class	EFCAB11 SLC26A4 MYO5C FARP2 GSN RNF2 TEKT4	2.73e-05	199	194	7	a2f154b15087803958a656d2a41b6d83fd37b32f
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-MAIT\|Int-URO / Disease, condition lineage and cell class	PACSIN3 MYO5C SYNE2 JAKMIP1 RGPD5 LCK CCDC65	2.82e-05	200	194	7	043c18e79a969e37bbff86443e553ac09fe33f84
ToppCell	MS-IIF\|MS / Disease, condition lineage and cell class	CWF19L2 TSPYL2 IQGAP1 ZNF394 FBXO7 RGPD5 TEKT4	2.82e-05	200	194	7	221f59edcfc18baece13184c2552d26022228146
ToppCell	severe_influenza-Treg\|World / disease group, cell group and cell class (v2)	HECW1 APC2 NDC80 JAKMIP1 CPE LCK	4.90e-05	149	194	6	2a3a00cdf604c8f3f3863df0ddb06938549bf86d
ToppCell	facs-Lung-3m-Hematologic-Lymphocytic_NK_ILC\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIMAP4 EPSTI1 JAKMIP1 PREX1 ARHGEF18 LCK	5.08e-05	150	194	6	1f83e3be3f94aefe991a3ccd292c2d11ddef858e
ToppCell	facs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIMAP4 EPSTI1 JAKMIP1 PREX1 ARHGEF18 LCK	5.08e-05	150	194	6	cd666db614bc1b43d71e8eb7bf38cae4d580be80
ToppCell	facs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIMAP4 EPSTI1 JAKMIP1 PREX1 ARHGEF18 LCK	5.08e-05	150	194	6	f6ed3e7b36014d1e429b255b0027d89865e1ac07
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPSTI1 RHPN1 JAKMIP1 PREX1 LCK PCED1B	5.67e-05	153	194	6	ad33c81fe6ac10e7c263d42541aae0d796923bad
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPSTI1 RHPN1 JAKMIP1 PREX1 LCK PCED1B	5.67e-05	153	194	6	2a94092937267cd2282452dfde3d328d763d4294
ToppCell	IIH-CD8-exh_CD4\|IIH / Condition, Cell_class and T cell subcluster	KIF18A HECW1 IQGAP2 ZNF549 SPTBN1 ZBTB40	5.88e-05	154	194	6	a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GIMAP4 EPSTI1 IQGAP2 MCM7 DNMBP LCK	6.32e-05	156	194	6	33deda19f06172079ef1dd49fd54d66da1e7fb14
Drug	purealin	MYH11 MYLK MYO1A MYO5A MYO5C MYO3B DNAH9 MYO18A	3.33e-08	58	195	8	CID006419303
Drug	blebbistatin	MYH11 MYLK MYO1A MYO5A MYO7A MYO5C MYO3B MYO18A LCK	7.14e-07	116	195	9	CID003476986
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	PDK1 DISC1 NKX3-2 MAPK8IP3 DNAJC28 ZBTB40 ATN1 MUC5B RABEP1 R3HDM1 GRAMD1C	1.07e-06	196	195	11	990_UP
Drug	S-(-)-Etomoxir	MYH11 ACACA MYO1A MYO5A ACOX1 MYO5C MYO3B MYO18A	2.38e-06	100	195	8	CID000060765
Drug	MgCl2	MYH11 HK2 MYLK MYO1A MYO5A SPTBN1 MYO5C CDH20 MYO3B DNAH9 POLG MYO18A GSN PRM2	2.42e-06	354	195	14	CID000024584
Drug	formycin triphosphate	MYH11 MYO1A MYO5A MYO5C MYO3B MYO18A	4.78e-06	51	195	6	CID000122274
Drug	Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A	PDK1 IQGAP1 DNAJC28 ATN1 PPP1R9A PEX3 DVL3 GSN PAX5 PCDHGC3	6.18e-06	191	195	10	3926_DN
Drug	B0683	MYH11 MYLK MYO1A MYO5A MYO5C MYO3B OXSM MYO18A	7.71e-06	117	195	8	CID006398969
Drug	Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A	DISC1 SPTBN1 NKX3-2 MAPK8IP3 CARD14 ATN1 MUC5B CPE R3HDM1 GRAMD1C	7.76e-06	196	195	10	4423_DN
Drug	phosphotyrosine (pY	TRIT1 ACACA HECW1 ACP2 UBE2E3 IRS4 WWP1 LCK CEP131 TP53	1.06e-05	203	195	10	CID000030819
Drug	mantATP	MYO5A MYO5C PKLR OXSM DNAH9	1.15e-05	35	195	5	CID000123756
Drug	Zinc Sulfate	MYH11 HK2 IQGAP2 SPTBN1 APC2 HJURP NKX3-2 CRLF3 EEF2K NKX2-2 KAZN MTCL1 CNTF PTGES2 TRPV1 ARHGEF18 LCK TP53 NIN	2.12e-05	739	195	19	ctd:D019287
Drug	AC1NPJ0T	MYO5A MYO5C PKLR OXSM	2.27e-05	20	195	4	CID005159168
Drug	trifluoperazine	MYH11 MYLK ACACA MYO1A MYO5A SPTBN1 MYO5C MYO3B EEF2K ANXA11 MYO18A PRKG2	2.47e-05	324	195	12	CID000005566
Drug	clenbuterol	MYH11 MYO1A MYO5A MYO5C SAFB MYO3B MYO18A SAFB2	3.16e-05	142	195	8	CID000002783
Drug	K-Cl	MYH11 MYLK MYO1A MYO5A MYO5C SAFB MYO3B CGN EEF2K OXSM CARD14 POLG MYO18A CPE GSN SAFB2	3.24e-05	567	195	16	CID000004873
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A	PDK1 INPP5B MAPK8IP3 JAG2 NDC80 CPE C2orf68 ENTPD4 PDZRN3	4.33e-05	192	195	9	2865_DN
Drug	troglitazone; Down 200; 10uM; PC3; HG-U133A	KIF18A DHX38 PACSIN3 FARP2 SAFB MUC5B ENTPD4 R3HDM1 PARD3	4.51e-05	193	195	9	462_DN
Drug	Bepridil hydrochloride [74764-40-2]; Down 200; 10uM; HL60; HT_HG-U133A	PIDD1 JAG2 ZBTB40 ABCC1 PTGES2 POLG GSN SNIP1 PARD3	4.88e-05	195	195	9	1274_DN
Drug	aminocarb	FARP2 DNMBP CPE	5.00e-05	9	195	3	CID000016247
Disease	retinal vasculature measurement	MYO5A NBEAL1 SPTBN1 HLA-DRB5 MCM7 FARP2 MYO3B HERC2 DNAH9 TPCN2 MUC12 STRIP1 ZNF106 FRY R3HDM1 TINCR	2.21e-07	517	187	16	EFO_0010554
Disease	sarcoidosis	MANBA HLA-DQB2 HLA-DRB5 CCDC88B ANXA11 GPSM3	3.30e-06	64	187	6	MONDO_0019338
Disease	mean platelet volume	MYH11 RNLS IQGAP2 MYO5A ACOX1 SPTBN1 TRANK1 CRLF3 EXOC3L4 SYNE2 HTR3D MCF2L HOMEZ PCDHGC5 NARF FRY RABEP1 STK38L PCDHGC3 NIN	8.29e-06	1020	187	20	EFO_0004584
Disease	colorectal cancer (implicated_via_orthology)	APC2 LCK FRK HCK	3.76e-05	30	187	4	DOID:9256 (implicated_via_orthology)
Disease	cutaneous melanoma	HLA-DQB2 SYNE2 HERC2 TPCN2 PARD3 TP53	1.26e-04	121	187	6	EFO_0000389
Disease	visual masking mesurement	SAFB2 PAX5	2.38e-04	4	187	2	EFO_0803378
Disease	Megacystis microcolon intestinal hypoperistalsis syndrome	MYH11 MYLK	2.38e-04	4	187	2	C1608393
Disease	hepatocellular carcinoma (implicated_via_orthology)	IQGAP2 MCM7 UACA POLG	2.65e-04	49	187	4	DOID:684 (implicated_via_orthology)
Disease	alkaline phosphatase measurement	MANBA SLC26A4 SPTBN1 DHX38 WDR81 FARP2 TRANK1 EXOC3L4 ZBTB40 UBE2E3 GOLGB1 HOMEZ ADAMTS2 GSN FRK RNF2 STK38L	2.69e-04	1015	187	17	EFO_0004533
Disease	non-melanoma skin carcinoma	HLA-DQB2 CCDC88B HERC2 TSGA10IP DGKZ PARD3 EPB41 TP53	3.05e-04	265	187	8	EFO_0009260
Disease	megacystis-microcolon-intestinal hypoperistalsis syndrome (is_implicated_in)	MYH11 MYLK	3.95e-04	5	187	2	DOID:0060610 (is_implicated_in)
Disease	remission, hepatitis C virus infection	HLA-DQB2 HLA-DRB5 PARD3	4.04e-04	23	187	3	EFO_0003047, EFO_0009785
Disease	Liver carcinoma	KIF18A ACACA EAF2 IQGAP2 ACOX1 HJURP IQGAP1 NDC80 CSPG4 CEP131 TP53	4.17e-04	507	187	11	C2239176
Disease	Congenital muscular dystrophy (disorder)	ITGA7 SYNE2	5.89e-04	6	187	2	C0699743
Disease	Intellectual Disability	DISC1 APC2 LAMA1 MAPK8IP3 ZBTB40 ATN1 PUF60 ZCCHC8 WDR26 FRY	6.02e-04	447	187	10	C3714756
Disease	lean body mass	KIZ APC2 ZBTB40 KAZN LCORL DIDO1 MST1R PRKG2 TP53	7.40e-04	379	187	9	EFO_0004995
Disease	lymphocyte count	GIMAP4 MANBA ACACA IQGAP2 HLA-DQB2 SLC26A4 HLA-DRB5 IQGAP1 CRLF3 PREX1 ABCC1 GLT6D1 PTGES2 TPCN2 PCDHGC5 LCORL ARHGEF18 MST1R RABEP1 PCDHGC3	1.05e-03	1464	187	20	EFO_0004587
Disease	intestinal cancer (implicated_via_orthology)	LCK FRK HCK	1.09e-03	32	187	3	DOID:10155 (implicated_via_orthology)
Disease	hepatitis B virus infection, Susceptibility to viral and mycobacterial infections	HLA-DQB2 HLA-DRB3	1.09e-03	8	187	2	EFO_0004197, Orphanet_391311
Disease	lupus nephritis	HLA-DQB2 KIZ NIN	1.19e-03	33	187	3	EFO_0005761
Disease	serum alanine aminotransferase measurement	EFCAB11 MANBA HLA-DQB2 DISC1 HLA-DRB3 TRANK1 CDH20 DNMBP PTGES2 TPCN2 LCORL ZCCHC8 FRK NIN	1.36e-03	869	187	14	EFO_0004735
Disease	Epstein Barr virus nuclear antigen 1 IgG measurement	HLA-DQB2 HLA-DRB5	1.40e-03	9	187	2	EFO_0007790
Disease	HLA class II histocompatibility antigen, DQ alpha 2 chain measurement	HLA-DQB2 HLA-DRB5	1.40e-03	9	187	2	EFO_0801686
Disease	primary biliary cirrhosis	MANBA HLA-DQB2 HLA-DRB3 CCDC88B EXOC3L4	1.62e-03	133	187	5	EFO_1001486
Disease	cancer (implicated_via_orthology)	ITGA7 NDC80 NKX2-2 LCK RNF2 HCK TP53	1.67e-03	268	187	7	DOID:162 (implicated_via_orthology)
Disease	CCL19 measurement	HLA-DQB2 HLA-DRB5	1.74e-03	10	187	2	EFO_0009415
Disease	Abnormality of nervous system morphology	APC2 MAPK8IP3	1.74e-03	10	187	2	C4022810
Disease	Familial thoracic aortic aneurysm and aortic dissection	MYH11 MYLK	1.74e-03	10	187	2	cv:C4707243
Disease	body fat distribution	PKLR TSGA10IP ADAMTS3 ADAMTS2 LCORL PRKG2	1.88e-03	202	187	6	EFO_0004341
Disease	Brain Neoplasms	IQGAP2 IQGAP1 TP53	1.94e-03	39	187	3	C0006118
Disease	Profound Mental Retardation	DISC1 LAMA1 ZBTB40 ZCCHC8 FRY	1.96e-03	139	187	5	C0020796
Disease	Mental Retardation, Psychosocial	DISC1 LAMA1 ZBTB40 ZCCHC8 FRY	1.96e-03	139	187	5	C0025363
Disease	Mental deficiency	DISC1 LAMA1 ZBTB40 ZCCHC8 FRY	1.96e-03	139	187	5	C0917816
Disease	pigmentation disease (is_implicated_in)	HERC2 TPCN2	2.12e-03	11	187	2	DOID:10123 (is_implicated_in)
Disease	lignoceroylcarnitine (C24) measurement	TPCN2 WWP1	2.12e-03	11	187	2	EFO_0800541
Disease	thoracic aortic aneurysm (is_implicated_in)	MYH11 MYLK	2.12e-03	11	187	2	DOID:14004 (is_implicated_in)
Disease	kidney disease (implicated_via_orthology)	LCK PALS1 HCK	2.24e-03	41	187	3	DOID:557 (implicated_via_orthology)
Disease	response to antihypertensive drug	EPSTI1 HLA-DQB2 MYO3B	2.24e-03	41	187	3	EFO_0005405
Disease	erectile dysfunction	ACACA PDK1 MATN2	2.40e-03	42	187	3	EFO_0004234
Disease	rac GTPase-activating protein 1 measurement	HLA-DQB2 HLA-DRB5	2.53e-03	12	187	2	EFO_0801985
Disease	B-Cell Lymphomas	EAF2 TP53	2.53e-03	12	187	2	C0079731
Disease	von Willebrand factor measurement, coagulation factor measurement	SAFB2 TINCR	2.53e-03	12	187	2	EFO_0004629, EFO_0004634
Disease	biliary liver cirrhosis	MANBA HLA-DQB2 EXOC3L4	2.74e-03	44	187	3	EFO_0004267
Disease	carbohydrate measurement	TINAG MYO18A GSN	3.11e-03	46	187	3	EFO_0004998
Disease	C-C motif chemokine 19 measurement	HLA-DQB2 HLA-DRB5	3.46e-03	14	187	2	EFO_0008047
Disease	X-21470 measurement	ZNF394 DNMBP	3.46e-03	14	187	2	EFO_0800817
Disease	L2 Acute Lymphoblastic Leukemia	PAX5 HCK TP53	3.94e-03	50	187	3	C0023453
Disease	liver neoplasm	HLA-DQB2 HLA-DRB3	3.97e-03	15	187	2	EFO_1001513
Disease	severe aplastic anemia	EPSTI1 HLA-DRB3	3.97e-03	15	187	2	EFO_0006927
Disease	nasopharynx carcinoma (is_implicated_in)	MST1R TP53	3.97e-03	15	187	2	DOID:9261 (is_implicated_in)
Disease	C-reactive protein measurement	GIMAP4 CWF19L2 ARPP21 HLA-DQB2 MAPK8IP3 FARP2 TRANK1 PELO ZBTB40 UBR2 LCORL DGKZ HID1 MST1R FRK ZNF106	4.41e-03	1206	187	16	EFO_0004458
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	HLA-DQB2 FRY PARD3	4.41e-03	52	187	3	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	Childhood Acute Lymphoblastic Leukemia	PAX5 HCK TP53	4.41e-03	52	187	3	C0023452
Disease	Cardiovascular Abnormalities	APC2 ATN1	4.52e-03	16	187	2	C0243050
Disease	gastroparesis	HLA-DQB2 HLA-DRB3	4.52e-03	16	187	2	EFO_1000948
Disease	Peripheral Nervous System Diseases	MYO5A GFAP ABCC1	4.90e-03	54	187	3	C4721453
Disease	response to interferon-beta, anti-drug antibody measurement	HLA-DQB2 HLA-DRB5	5.10e-03	17	187	2	EFO_0010559, GO_0035456
Disease	level of Sphingomyelin (d32:1) in blood serum	SYNE2 RABEP1	5.10e-03	17	187	2	OBA_2045173
Disease	Colorectal Carcinoma	ACACA APC2 LAMA1 BMPR1A JAKMIP1 ABCD2 ABCC1 IRS4 CPE LRRC3B TP53	5.36e-03	702	187	11	C0009402
Disease	Amyotrophic Lateral Sclerosis	GFAP ANXA11 TP53	5.98e-03	58	187	3	C0002736
Disease	fibrinogen measurement, factor VII measurement	GIMAP4 MCF2L PARD3	5.98e-03	58	187	3	EFO_0004619, EFO_0004623
Disease	skin aging measurement	MYH11 RNLS SYNE2 LCORL PEX3	6.05e-03	181	187	5	EFO_0008006

Protein segments in the cluster

Peptide	Gene	Start	Entry
NIYNIAADRIRHEEA	URB2	371	Q14146
QEVHRFVVREYLARA	EXOC3L4	571	Q17RC7
RERLDGENIYIRHSN	EPB41	651	P11171
RAELERQRQAYQHDL	ARHGEF18	1106	Q6ZSZ5
RQRQAYQHDLERLRE	ARHGEF18	1111	Q6ZSZ5
YQHDLERLREAQRAV	ARHGEF18	1116	Q6ZSZ5
DRNEEYRRQFTHLPD	GRAMD1C	66	Q8IYS0
RSRAHLVAVFNEYQR	ANXA11	386	P50995
SRDHLHREQREYLDQ	CCDC88B	1266	A6NC98
FHQRDVEQGRVRYLS	CSPG4	731	Q6UVK1
HSRIIANVEEIAFYR	ABCD2	296	Q9UBJ2
IHSRESEDENRYIRN	CCDC65	281	Q8IXS2
SYAERLAAERQHAER	ATN1	1016	P54259
QQYRQHIQVFIDRFR	ABCF3	431	Q9NUQ8
HIQVFIDRFRYNANR	ABCF3	436	Q9NUQ8
FRKQVNYEVDRRFHR	ACACA	1336	Q13085
DLEQFERVHRYISDQ	DNMBP	1076	Q6XZF7
QRDEDENVNIYRARH	EEF1AKMT3	206	Q96AZ1
LYHNVEGFTDRREAR	DVL3	451	Q92997
VHHIRRNQIARDDYD	C2orf68	26	Q2NKX9
YNRLRREVEHQETAY	DISC1	646	Q9NRI5
EEYQRVRERIFAHDS	ARPP21	286	Q9UBL0
RARRHAADDDYNIEV	ADAMTS2	256	O95450
QREIEIRFDQLHREY	HJURP	431	Q8NCD3
RDRLQYFRDHINDII	IQGAP1	826	P46940
HCRAAYEDFNVQLRR	MUC5B	106	Q9HC84
YNLRRSALEIFHVDQ	NBEAL1	1946	Q6ZS30
REEEYQRARDRIFSQ	R3HDM1	286	Q15032
RSYEALRREHDAQIV	RC3H2	271	Q9HBD1
RRRVDFHDVQDYADN	RAB24	131	Q969Q5
RVAYVNFRHPQDARE	RBM15B	181	Q8NDT2
RLRVDFADTEHRYQQ	RBM15	521	Q96T37
FRNYNTSIDVRRHEL	PDZRN3	726	Q9UPQ7
RDQENHYTDRDYRKE	NSRP1	326	Q9H0G5
RDYEHQFHLRLEQER	RABEP1	126	Q15276
ENEQVVFSHRAEIYR	RGPD5	1351	Q99666
ENEQVVFSHRAEIYR	RGPD8	1351	O14715
YFQERNREHERHRDR	CPSF7	451	Q8N684
DERARLRLQQQYASD	MTCL1	1156	Q9Y4B5
VLDRVFERQHYSDIF	PAX5	236	Q02548
YDFTDTVIRIRNRHN	PDK1	136	Q15118
EEYEHAVQRRARIYA	OXSM	286	Q9NWU1
LRDFHRRYNQKNVSE	TRIT1	256	Q9H3H1
DQSIRESRHFQIDYD	MYLK	1846	Q15746
EAQSRRLEEQRATFY	GPSM3	71	Q9Y4H4
YQVNFSREALQERRA	KAZN	586	Q674X7
QHRYLFEEDNLLRST	MATN2	881	O00339
ERVRFLHRDIYNQEE	HLA-DRB5	51	Q30154
QYRQVREHVRNDDGR	MAPK8IP3	646	Q9UPT6
ANVAYQSLRDRDRDQ	MYO1A	81	Q9UBC5
VRLAINYRLHEFDEQ	HERC2	4631	O95714
NYRLHEFDEQVAAVR	HERC2	4636	O95714
RRDARNFERYQHNRD	HECW1	991	Q76N89
VDNRAVRSINEARYA	JAG2	1221	Q9Y219
SRSHAVFQIYLRQQD	KIF18A	226	Q8NI77
LHRNREDYVERSAEF	LCORL	261	Q8N3X6
NLRREAFREHQQYKT	EPSTI1	176	Q96J88
VTAVAYRLADQHRAR	HK2	456	P52789
RHNYEAELRTTLQRQ	HLA-DQB2	111	P05538
RHRGLIRAYEFAVDQ	FBXW8	551	Q8N3Y1
EESRFYEIHARARDQ	PCDHGC5	311	Q9Y5F6
RLFHERTFVQELERY	MYO18A	821	Q92614
AAFRNYIHRADARQE	PGAM5	206	Q96HS1
QEREAAEYIAQARRQ	PEX3	41	P56589
HNGLNYREVREFRSD	PCED1B	71	Q96HM7
ERVRYFHDDDNLSLN	CWF19L2	586	Q2TBE0
ARENVEAAQSYRREL	CRLF3	16	Q8IUI8
YITRQFVQFDERERH	DCSTAMP	246	Q9H295
EKHYRQFRADRAAEQ	DNAJC28	151	Q9NX36
VSFDRAHIREQYLIQ	POLG	271	P54098
REAEAAVYHRQLFEE	PKLR	426	P30613
AVYHRQLFEELRRAA	PKLR	431	P30613
EERNYIHRDLRAANI	LCK	356	P06239
LEREQEQRRHTAYIS	JAKMIP1	56	Q96N16
VVYYVRQNQEDARRH	LRRC3B	221	Q96PB8
ASQHVFRFYRESLQR	EXOSC5	216	Q9NQT4
LRVEYLDDRNTFRHS	TP53	201	P04637
REQEERHVREAASYQ	GFAP	311	P14136
RHVREAASYQEALAR	GFAP	316	P14136
RNEYFALRVQTREDS	PCDHGC3	176	Q9UN70
RNQEYLKRFERVQAH	KIZ	76	Q2M2Z5
QARDEQYRNFLRSVS	PRKG2	271	Q13237
DRDNDLRLAQHITYV	MCM7	526	P33993
RSRRDQEVAGRDYHF	PALS1	516	Q8N3R9
HRQEVYVRSTDFDRT	ACP2	96	P11117
ERRAYFDLQTHVIQV	PHF10	221	Q8WUB8
AQVFELERRFNHQRY	NKX3-2	216	P78367
YLTTRNAEFDRHEIQ	PALS2	311	Q9NZW5
ESRNYIHRDLAARNV	FRK	346	P42685
ERVRYLDRYFHNQEE	HLA-DRB3	51	P79483
FQHEDLNFLTRSQRY	ACOX1	46	Q15067
VATREDYRQVLRDHN	APC2	611	O95996
RRRRHAGENDYNIEV	ADAMTS3	246	O15072
FIEQRNYIHRDLRAA	HCK	371	P08631
EARDFQAARYDRHDR	KLHL21	256	Q9UJP4
RDQAYSARDSAQREI	CARD14	361	Q9BXL6
QYRIPDIDASHNRFR	EAF2	221	Q96CJ1
RYFRNHQVEELRLSD	GLT6D1	21	Q7Z4J2
YLRDFRDNTVRVQDT	FBXO7	376	Q9Y3I1
IHAIQRLDREERAQY	CDH20	116	Q9HBT6
ERLQENLQAYRTFHV	CNTF	71	P26441
ERRNVKRHQAYEFQF	TMEM63B	606	Q5T3F8
RRRYNRDLEQDEAFI	BMPR1A	186	P36894
RRLQQEDGISFEYHR	CPE	41	P16870
HEYRNQTFEGRQRER	DIDO1	2076	Q9BTC0
DTHEYRNESRRLQEF	CEMIP2	286	Q9UHN6
FYRRSRSEIVDQQGH	MANBA	636	O00462
FHNRIFLRELENYTD	MCF2L	691	O15068
LAAHIEEYERRNQDY	INPP5B	481	P32019
DDYLNGRAVQHREVQ	GSN	136	P06396
AHRYEARQRVDQILE	ITGA7	141	Q13683
DIATERATRHRYNAV	EEF2K	106	O00418
QEFQDRRENLHTYFK	DNAH9	406	Q9NYC9
LDRYSDRNHQITRYQ	FRY	1141	Q5TBA9
ETRARVVYRRDQLHF	HOMEZ	121	Q8IX15
RYREAARSEIQVLEH	CLK4	196	Q9HAZ1
DERVQRALHFVISEY	CST2	41	P09228
TTASRFYRIDRAQEH	DGKZ	721	Q13574
IYEFHRGFLREVEQR	FARP2	586	O94887
RYRNEVRHIFTAFDT	EFCAB11	91	Q9BUY7
ALSRQLQRQREHYEA	CEP131	611	Q9UPN4
SRDEYEAHQERVLAR	RNF2	116	Q99496
ALEHFDRYFLRQSQE	FTH1P19	11	P0C7X4
DRYFLRQSQEKREHA	FTH1P19	16	P0C7X4
GVSYREVQRIRHEFR	PIDD1	811	Q9HB75
NYRRTVQRVEDGHRL	PACSIN3	21	Q9UKS6
RERDYAEIQDFHRTF	PARD3	1076	Q8TEW0
ENEQVVFSHRAELYR	RGPD1	1336	P0DJD0
IYRAELRVRDINDHS	PCDHB9	116	Q9Y5E1
DARYRHLIALFTQDE	IRS4	161	O14654
HSRSRVFREVETLYQ	MKNK1	86	Q9BUB5
RYREDLDFVLRHINV	ABCC1	1301	P33527
RRQERQRFAEYQAEL	TSGA10IP	441	Q3SY00
SRYSHVQEVQERLNF	USP9X	646	Q93008
FYNARRREHRQRNDV	SNIP1	181	Q8TAD8
FYSNLILQHEERETR	STK38L	31	Q9Y2H1
EARAFNRIYVASVHQ	PUF60	221	Q9UHX1
RHFTNQREEFEGTRE	SYNE2	6241	Q8WXH0
QEAHYAVRQQRARTE	GIMAP4	286	Q9NUV9
DHHAAIERRNEYNLR	NIN	406	Q8N4C6
EEYFQEQNSLHDRRD	FAM89A	146	Q96GI7
LSRLQYFRDHNNEIV	IQGAP2	741	Q13576
QRNAVDLVYRAEDHA	LAMA1	1861	P25391
NAARQRYEDRIFANT	ENTPD4	331	Q9Y227
VNYLSRIHREEDFQF	HID1	326	Q8IV36
EVLEHFQAFRSRREE	PREX1	766	Q8TCU6
ERFNARRYDRAHSNP	STRIP1	776	Q5VSL9
RHLEFSHDQYRELQR	NANS	86	Q9NR45
RYHQAFADRDQSERQ	TEKT4	51	Q8WW24
RFRQQRYLSAPEREH	NKX2-2	146	O95096
SQHDRALERFYEQVV	PELO	176	Q9BRX2
ELFRHQDVATRSRYV	PELO	316	Q9BRX2
RHRLQDNVREDLYEA	PTGES2	296	Q9H7Z7
RLQQAEESIRYSRQH	WHAMM	496	Q8TF30
RTYNFTQDRVSDHRI	MTRF1	386	O75570
TQDRVSDHRIAYEVR	MTRF1	391	O75570
QEAAQVAAEYRLVHR	RHPN1	311	Q8TCX5
LAAHVEDFERRNQDY	OCRL	376	Q01968
ALDERYHSDFNRQDR	SAFB	731	Q15424
RRLEEAHRAQQYYFD	SPTBN1	1586	Q01082
TNQYEQAIFHVAIRR	HTR3D	211	Q70Z44
EHVRQQYQRDTEQLR	CGN	516	Q9P2M7
HSRTLAEYIRNNYRE	C12orf56	571	Q8IXR9
AIRQARDERTFHIFY	MYH11	271	P35749
QEVARDYRDLFHRDF	TMX3	271	Q96JJ7
RTTNREYFLIGHDRE	PLEKHS1	101	Q5SXH7
VRSLSERSHEVYRQQ	PRM2	6	P04554
QQRYHAEEVEERFGR	ZCCHC8	271	Q6NZY4
LLQETFTADRRHQRY	nan	466	Q6ZTK2
FTADRRHQRYSLETR	nan	471	Q6ZTK2
ETSRLHFRQLRYQEV	ZNF394	61	Q53GI3
HRSRETFQQRRYKCE	ZNF549	211	Q6P9A3
NRRDEDIFRYLTNLQ	TSPYL2	281	Q9H2G4
VYSELAFQQQHERRL	SLC26A4	26	O43511
RLYDRRSIFEAVAQN	TRPV1	111	Q8NER1
VYFRHRVTQINLRDD	RNLS	126	Q5VYX0
QYLTNRAEHDRIARQ	UBE2E3	186	Q969T4
DSQTHYRLREAQDRA	TMED3	156	Q9Y3Q3
AYSSEDYVRRREQHL	DHX38	341	Q92620
RDRGQYQDHAIDRRE	SAFB2	771	Q14151
FYYNARRLDDHQTVR	TINCR	56	A0A2R8Y7D0
ADADRQHQEVIAIYR	UACA	1371	Q9BZF9
LHRYYQNAATDVRRV	ZUP1	326	Q96AP4
HQRIRGYNFEDLTDR	WDR26	506	Q9H7D7
TFRQRFRRFHYQEVA	ZSCAN29	16	Q8IWY8
QREVDLEAYFTRNHT	TINAG	26	Q9UJW2
VDDRRRVYYVDHNTR	WWP1	391	Q9H0M0
YIHFLFENESARNRR	TRANK1	2266	O15050
RQQRLRLHTSYDVEN	UBR2	1191	Q8IWV8
EAIVYRHRQALESQD	WDR87	2571	Q6ZQQ6
VLETSHQNFRRFRYQ	ZNF202	41	O95125
RDILDREYYSVQQHR	MST1R	1231	Q04912
FVRVYELQSHDRLQV	ZNF106	1761	Q9H2Y7
HRFILLYQARRVEDE	WDR81	881	Q562E7
VFIEDAIQYRSINHR	TPCN2	51	Q8NHX9
LRRYHENLSEIFTDN	ZBTB40	466	Q9NUA8
AERQRRLDYESQTAH	GOLGB1	776	Q14789
FSLSQRKRHREQYDV	MUC12	5401	Q9UKN1
ESQKEFVRRYRQHSE	NARF	146	Q9UHQ1
FVRRYRQHSEEERTL	NARF	151	Q9UHQ1
ESYRRQFEAIQHCFR	MYO3B	576	Q8WXR4
KSRVVFQAEEERNYH	MYO5A	246	Q9Y4I1
RVVFQSENERNYHIF	MYO5C	246	Q9NQX4
AAAQVFEQRIYAERR	NACC2	486	Q96BF6
RVCRQALDERNYHVF	MYO7A	241	Q13402
YSVADIERINHERNE	NDC80	361	O14777
RRQRELLEQHYAQYD	PPP1R9A	611	Q9ULJ8