Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranslation activator activity

DAZ1 DAZ3 DAZ2 DAZ4

2.75e-0815444GO:0008494
GeneOntologyMolecularFunctiontranslation regulator activity, nucleic acid binding

DAZ1 DAZ3 DAZ2 DAZ4

1.07e-04112444GO:0090079
GeneOntologyMolecularFunctionmRNA 3'-UTR binding

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

3.40e-04276445GO:0003730
GeneOntologyBiologicalProcessfemale meiosis II

DAZ1 DAZ3 DAZ2 DAZ4

2.69e-106444GO:0007147
GeneOntologyBiologicalProcessmeiosis II

DAZ1 DAZ3 DAZ2 DAZ4

2.69e-106444GO:0007135
GeneOntologyBiologicalProcessmeiosis II cell cycle process

DAZ1 DAZ3 DAZ2 DAZ4

2.69e-106444GO:0061983
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA stabilization

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

5.70e-0931445GO:0070935
GeneOntologyBiologicalProcesspositive regulation of meiotic nuclear division

DAZ1 DAZ3 DAZ2 DAZ4

2.60e-0726444GO:0045836
GeneOntologyBiologicalProcesspositive regulation of translational initiation

DAZ1 DAZ3 DAZ2 DAZ4

4.11e-0729444GO:0045948
GeneOntologyBiologicalProcessmRNA stabilization

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

6.16e-0777445GO:0048255
GeneOntologyBiologicalProcessanatomical structure maturation

TGFB2 DAZ1 ACVRL1 DAZ3 DAZ2 DAZ4 RYR1 CSPG4

7.19e-07354448GO:0071695
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

DAZ1 DAZ3 DAZ2 DAZ4

1.13e-0637444GO:0051446
GeneOntologyBiologicalProcessnegative regulation of mRNA catabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

1.13e-0687445GO:1902373
GeneOntologyBiologicalProcessRNA stabilization

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

1.20e-0688445GO:0043489
GeneOntologyBiologicalProcessnegative regulation of RNA catabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

2.38e-06101445GO:1902369
GeneOntologyBiologicalProcessregulation of meiotic nuclear division

DAZ1 DAZ3 DAZ2 DAZ4

2.52e-0645444GO:0040020
GeneOntologyBiologicalProcessoocyte maturation

DAZ1 DAZ3 DAZ2 DAZ4

3.00e-0647444GO:0001556
GeneOntologyBiologicalProcessdevelopmental maturation

TGFB2 DAZ1 ACVRL1 DAZ3 DAZ2 DAZ4 RYR1 CSPG4

3.58e-06439448GO:0021700
GeneOntologyBiologicalProcessnegative regulation of mRNA metabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

4.51e-06115445GO:1903312
GeneOntologyBiologicalProcessfemale meiotic nuclear division

DAZ1 DAZ3 DAZ2 DAZ4

4.52e-0652444GO:0007143
GeneOntologyBiologicalProcesspositive regulation of translation

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

1.70e-05151445GO:0045727
GeneOntologyBiologicalProcesspositive regulation of nuclear division

DAZ1 DAZ3 DAZ2 DAZ4

1.96e-0575444GO:0051785
GeneOntologyBiologicalProcesspositive regulation of cardioblast differentiation

TGFB2 NKX2-5

2.66e-054442GO:0051891
GeneOntologyBiologicalProcessregulation of meiotic cell cycle

DAZ1 DAZ3 DAZ2 DAZ4

2.79e-0582444GO:0051445
GeneOntologyBiologicalProcessregulation of translational initiation

DAZ1 DAZ3 DAZ2 DAZ4

4.20e-0591444GO:0006446
GeneOntologyBiologicalProcessregulation of cardioblast differentiation

TGFB2 NKX2-5

4.43e-055442GO:0051890
GeneOntologyBiologicalProcessoocyte development

DAZ1 DAZ3 DAZ2 DAZ4

5.85e-0599444GO:0048599
GeneOntologyBiologicalProcessoocyte differentiation

DAZ1 DAZ3 DAZ2 DAZ4

6.83e-05103444GO:0009994
GeneOntologyBiologicalProcessapoptotic process involved in heart morphogenesis

TGFB2 NKX2-5

9.28e-057442GO:0003278
GeneOntologyBiologicalProcesspositive regulation of reproductive process

DAZ1 DAZ3 DAZ2 DAZ4

1.16e-04118444GO:2000243
GeneOntologyBiologicalProcessepiboly involved in wound healing

ARHGAP35 ACVRL1 CLASP1

1.29e-0446443GO:0090505
GeneOntologyBiologicalProcesswound healing, spreading of cells

ARHGAP35 ACVRL1 CLASP1

1.29e-0446443GO:0044319
GeneOntologyBiologicalProcessepiboly

ARHGAP35 ACVRL1 CLASP1

1.38e-0447443GO:0090504
GeneOntologyBiologicalProcesstranslational initiation

DAZ1 DAZ3 DAZ2 DAZ4

1.78e-04132444GO:0006413
GeneOntologyBiologicalProcesspositive regulation of extracellular matrix disassembly

TGFB2 CLASP1

1.98e-0410442GO:0090091
GeneOntologyBiologicalProcesscellular response to caffeine

SELENON RYR1

2.42e-0411442GO:0071313
GeneOntologyBiologicalProcesscell maturation

DAZ1 DAZ3 DAZ2 DAZ4 CSPG4

2.52e-04267445GO:0048469
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

TGFB2 ACVRL1 SELENON SAP130 RYR1

2.93e-04276445GO:0007179
GeneOntologyBiologicalProcessoogenesis

DAZ1 DAZ3 DAZ2 DAZ4

3.38e-04156444GO:0048477
GeneOntologyBiologicalProcessregulation of mRNA stability

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

3.80e-04292445GO:0043488
GeneOntologyBiologicalProcesscellular response to purine-containing compound

SELENON RYR1

3.98e-0414442GO:0071415
GeneOntologyBiologicalProcessregulation of RNA stability

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

4.84e-04308445GO:0043487
GeneOntologyBiologicalProcessregulation of nuclear division

DAZ1 DAZ3 DAZ2 DAZ4

4.89e-04172444GO:0051783
GeneOntologyBiologicalProcessregulation of mRNA catabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

4.92e-04309445GO:0061013
GeneOntologyBiologicalProcessmorphogenesis of an epithelial sheet

ARHGAP35 ACVRL1 CLASP1

5.28e-0474443GO:0002011
GeneOntologyBiologicalProcesscollagen fibril organization

TGFB2 SELENON LOXL1

5.71e-0476443GO:0030199
GeneOntologyBiologicalProcessventricular trabecula myocardium morphogenesis

TGFB2 NKX2-5

5.93e-0417442GO:0003222
GeneOntologyBiologicalProcessaorta development

TGFB2 ACVRL1 LOXL1

6.64e-0480443GO:0035904
GeneOntologyBiologicalProcesscardioblast differentiation

TGFB2 NKX2-5

6.66e-0418442GO:0010002
GeneOntologyBiologicalProcessatrial septum morphogenesis

TGFB2 NKX2-5

6.66e-0418442GO:0060413
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

TGFB2 ACVRL1 SELENON SAP130 RYR1

7.18e-04336445GO:0071560
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

TGFB2 ACVRL1 SELENON SAP130 RYR1

7.88e-04343445GO:0071559
GeneOntologyBiologicalProcessvenous blood vessel development

NKX2-5 ACVRL1

8.25e-0420442GO:0060841
GeneOntologyBiologicalProcessepithelial to mesenchymal transition

TGFB2 USF3 ACVRL1 CLASP1

9.09e-04203444GO:0001837
GeneOntologyBiologicalProcesspositive regulation of cardiocyte differentiation

TGFB2 NKX2-5

9.10e-0421442GO:1905209
GeneOntologyBiologicalProcesscardiac right ventricle morphogenesis

TGFB2 NKX2-5

9.10e-0421442GO:0003215
GeneOntologyBiologicalProcessresponse to caffeine

SELENON RYR1

9.10e-0421442GO:0031000
GeneOntologyBiologicalProcessspermatogenesis

DMXL2 DAZ1 DAZ3 DAZ2 RNF114 DAZ4 CCDC34

9.24e-04744447GO:0007283
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

TGFB2 ENAM NKX2-5 PHOX2A CDX2 TBX4 ARHGAP35 ACVRL1 CLASP1 CSPG4

9.29e-0414834410GO:0048646
GeneOntologyBiologicalProcessoutflow tract morphogenesis

TGFB2 NKX2-5 RYR1

1.06e-0394443GO:0003151
GeneOntologyBiologicalProcessmale gamete generation

DMXL2 DAZ1 DAZ3 DAZ2 RNF114 DAZ4 CCDC34

1.06e-03762447GO:0048232
GeneOntologyBiologicalProcessmesenchyme development

TGFB2 NKX2-5 USF3 ACVRL1 CLASP1

1.13e-03372445GO:0060485
GeneOntologyBiologicalProcessmRNA catabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

1.15e-03373445GO:0006402
GeneOntologyBiologicalProcessfemale gamete generation

DAZ1 DAZ3 DAZ2 DAZ4

1.29e-03223444GO:0007292
GeneOntologyBiologicalProcessregulation of extracellular matrix disassembly

TGFB2 CLASP1

1.29e-0325442GO:0010715
GeneOntologyBiologicalProcessatrial septum development

TGFB2 NKX2-5

1.29e-0325442GO:0003283
GeneOntologyBiologicalProcesspositive regulation of organelle organization

DAZ1 ARHGAP35 DAZ3 DAZ2 CLASP1 DAZ4

1.30e-03574446GO:0010638
GeneOntologyBiologicalProcesspositive regulation of stem cell differentiation

TGFB2 NKX2-5

1.51e-0327442GO:2000738
GeneOntologyBiologicalProcessoutflow tract septum morphogenesis

TGFB2 NKX2-5

1.62e-0328442GO:0003148
GeneOntologyBiologicalProcesswound healing, spreading of epidermal cells

ACVRL1 CLASP1

1.62e-0328442GO:0035313
GeneOntologyBiologicalProcessstriated muscle cell proliferation

TGFB2 NKX2-5 SELENON

1.67e-03110443GO:0014855
GeneOntologyBiologicalProcesspositive regulation of cell cycle

TGFB2 DAZ1 DAZ3 DAZ2 DAZ4

1.68e-03407445GO:0045787
GeneOntologyBiologicalProcessmeiotic nuclear division

DAZ1 DAZ3 DAZ2 DAZ4

1.68e-03240444GO:0140013
GeneOntologyBiologicalProcessnegative regulation of catabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

1.89e-03418445GO:0009895
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

TGFB2 NKX2-5 TBX4 ARHGAP35 ACVRL1 CLASP1

1.91e-03619446GO:0002009
GeneOntologyBiologicalProcessregulation of reproductive process

DAZ1 DAZ3 DAZ2 DAZ4

1.98e-03251444GO:2000241
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

TGFB2 DAZ1 KIDINS220 ARHGAP35 ACVRL1 DAZ3 DAZ2 CLASP1 DAZ4

2.05e-031366449GO:0051130
GeneOntologyBiologicalProcessapoptotic process involved in morphogenesis

TGFB2 NKX2-5

2.12e-0332442GO:0060561
GeneOntologyBiologicalProcessRNA catabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

2.18e-03432445GO:0006401
GeneOntologyBiologicalProcessmuscle organ development

TGFB2 NKX2-5 ZNF609 SELENON RYR1

2.27e-03436445GO:0007517
GeneOntologyBiologicalProcesspharyngeal system development

TGFB2 NKX2-5

2.39e-0334442GO:0060037
GeneOntologyBiologicalProcesspositive regulation of extracellular matrix organization

TGFB2 CLASP1

2.39e-0334442GO:1903055
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

2.44e-03443445GO:1903311
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

TGFB2 ACVRL1 SELENON SAP130 RYR1

2.48e-03445445GO:0141091
GeneOntologyBiologicalProcessmeiotic cell cycle process

DAZ1 DAZ3 DAZ2 DAZ4

2.52e-03268444GO:1903046
GeneOntologyBiologicalProcesscardiac atrium morphogenesis

TGFB2 NKX2-5

2.53e-0335442GO:0003209
GeneOntologyBiologicalProcessregulation of epithelial to mesenchymal transition

TGFB2 USF3 CLASP1

2.68e-03130443GO:0010717
GeneOntologyBiologicalProcessregulation of cardiocyte differentiation

TGFB2 NKX2-5

2.82e-0337442GO:1905207
GeneOntologyBiologicalProcesschordate embryonic development

TGFB2 NKX2-5 CDX2 KIDINS220 ARHGAP35 ACVRL1 BIRC6

2.85e-03906447GO:0043009
GeneOntologyBiologicalProcessartery development

TGFB2 ACVRL1 LOXL1

2.86e-03133443GO:0060840
GeneOntologyBiologicalProcessembryo development

TGFB2 NKX2-5 CDX2 TBX4 KIDINS220 ARHGAP35 ACVRL1 CLASP1 BIRC6

2.89e-031437449GO:0009790
GeneOntologyBiologicalProcessnucleic acid catabolic process

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

2.97e-03464445GO:0141188
GeneOntologyBiologicalProcessheart trabecula morphogenesis

TGFB2 NKX2-5

2.98e-0338442GO:0061384
GeneOntologyBiologicalProcessnegative regulation of cytokine production involved in immune response

TGFB2 TBX21

3.13e-0339442GO:0002719
HumanPhenoOligozoospermia

DAZ1 DAZ3 DAZ2 DAZ4 CCDC34

3.10e-0659215HP:0000798
HumanPhenoY-linked inheritance

DAZ1 DAZ3 DAZ2

4.74e-0518213HP:0001450
HumanPhenoType 1 and type 2 muscle fiber minicore regions

SELENON RYR1

4.84e-053212HP:0003787
HumanPhenoDecreased testicular size

DMXL2 DAZ1 DAZ3 DAZ2 DAZ4 CCDC34

1.12e-04200216HP:0008734
MousePhenoabsent ovarian follicles

DAZ1 DAZ3 DAZ2 DAZ4

9.50e-0651374MP:0002777
DomainRhoGAP-FF1

ARHGAP5 ARHGAP35

4.94e-062422PF16512
DomainRhoGAP-FF1

ARHGAP5 ARHGAP35

4.94e-062422IPR032835
DomainFF

ARHGAP5 ARHGAP35

7.36e-056422PF01846
DomainFF

ARHGAP5 ARHGAP35

7.36e-056422SM00441
DomainFF

ARHGAP5 ARHGAP35

7.36e-056422PS51676
DomainFF_domain

ARHGAP5 ARHGAP35

7.36e-056422IPR002713
DomainRRM

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

1.21e-04217425SM00360
DomainRRM_dom

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

1.50e-04227425IPR000504
DomainRRM

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

1.59e-04230425PS50102
Domain-

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

2.09e-042444253.30.70.330
DomainARM-rpt_dom

GPRASP1 GPRASP2

2.68e-0411422IPR006911
DomainArm_2

GPRASP1 GPRASP2

2.68e-0411422PF04826
DomainNucleotide-bd_a/b_plait

LARP4B DAZ1 DAZ3 DAZ2 DAZ4

2.71e-04258425IPR012677
DomainTF_T-box

TBX4 TBX21

6.57e-0417422IPR001699
DomainTBOX_3

TBX4 TBX21

6.57e-0417422PS50252
DomainTBOX

TBX4 TBX21

6.57e-0417422SM00425
DomainTF_T-box_CS

TBX4 TBX21

6.57e-0417422IPR018186
DomainT-box

TBX4 TBX21

6.57e-0417422PF00907
Domain-

TBX4 TBX21

6.57e-04174222.60.40.820
DomainTBOX_1

TBX4 TBX21

6.57e-0417422PS01283
DomainTBOX_2

TBX4 TBX21

6.57e-0417422PS01264
DomainRRM_1

DAZ1 DAZ3 DAZ2 DAZ4

1.20e-03208424PF00076
Domainp53-like_TF_DNA-bd

TBX4 TBX21

6.33e-0353422IPR008967
DomainQuinoprotein_ADH-like_supfam

DMXL2 AHCTF1

6.33e-0353422IPR011047
DomainHomeodomain-like

NKX2-5 PHOX2A CDX2 FMO1

6.45e-03332424IPR009057
DomainHomeobox_CS

NKX2-5 PHOX2A CDX2

8.39e-03186423IPR017970
DomainRhoGAP

ARHGAP5 ARHGAP35

8.57e-0362422SM00324
DomainRhoGAP

ARHGAP5 ARHGAP35

8.84e-0363422PF00620
DomainRHOGAP

ARHGAP5 ARHGAP35

9.11e-0364422PS50238
DomainRhoGAP_dom

ARHGAP5 ARHGAP35

9.11e-0364422IPR000198
Domain-

ARHGAP5 ARHGAP35

9.11e-03644221.10.555.10
DomainHTH_motif

PHOX2A CDX2

1.05e-0269422IPR000047
PathwayWP_OVARIAN_INFERTILITY

DAZ1 DAZ3 DAZ2 DAZ4

1.24e-0635334MM15948
PathwayREACTOME_RND1_GTPASE_CYCLE

ARHGAP5 KIDINS220 ARHGAP35

1.26e-0442333M41828
PathwayREACTOME_RND2_GTPASE_CYCLE

ARHGAP5 KIDINS220 ARHGAP35

1.35e-0443333M41827
PathwayREACTOME_RND1_GTPASE_CYCLE

ARHGAP5 KIDINS220 ARHGAP35

1.35e-0443333MM15679
PathwayREACTOME_RND2_GTPASE_CYCLE

ARHGAP5 KIDINS220 ARHGAP35

1.45e-0444333MM15678
PathwayWP_MALE_INFERTILITY

DAZ1 DAZ3 DAZ2 DAZ4

3.48e-04145334M39856
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

DAZ1 CDX2 DAZ3 DAZ2 DAZ4

6.24e-04301335MM15983
PathwayREACTOME_RHOJ_GTPASE_CYCLE

ARHGAP5 ARHGAP35

6.25e-0416332MM15605
Pubmed

Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444415066457
Pubmed

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-1244447670487
Pubmed

Male infertility, genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444411694340
Pubmed

The human DAZ genes, a putative male infertility factor on the Y chromosome, are highly polymorphic in the DAZ repeat regions.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-1244449321470
Pubmed

Polymorphic expression of DAZ proteins in the human testis.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444419223287
Pubmed

Male infertility caused by a de novo partial deletion of the DAZ cluster on the Y chromosome.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444411095434
Pubmed

Impact of partial DAZ1/2 deletion and partial DAZ3/4 deletion on male infertility.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444426232607
Pubmed

[Microdeletion of chromosome Y in male infertility: role of the DAZ gene].

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444411688365
Pubmed

Polymorphic DAZ gene family in polymorphic structure of AZFc locus: Artwork or functional for human spermatogenesis?

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444412752250
Pubmed

A novel approach for the analysis of DAZ gene copy number in severely idiopathic infertile men.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444411883873
Pubmed

Four DAZ genes in two clusters found in the AZFc region of the human Y chromosome.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444410936047
Pubmed

[Study on DAZ gene copy deletion in severe oligozoospermia sperm donor for ICSI].

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444416963411
Pubmed

Partial DAZ deletions in a family with five infertile brothers.

DAZ1 DAZ3 DAZ2 DAZ4

2.23e-12444412801575
Pubmed

PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos.

DAZ1 CDX2 DAZ3 DAZ2 DAZ4

5.09e-121444525457166
Pubmed

Connecting cis-elements and trans-factors with mechanisms of developmental regulation of mRNA translation in meiotic and haploid mammalian spermatogenic cells.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544423579190
Pubmed

Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544422021443
Pubmed

The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154449288969
Pubmed

The dazzle in germ cell differentiation.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544420008336
Pubmed

Co-culture of spermatogonial stem cells with sertoli cells in the presence of testosterone and FSH improved differentiation via up-regulation of post meiotic genes.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544423456578
Pubmed

Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154448679003
Pubmed

In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544410903443
Pubmed

Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154449143498
Pubmed

Bisphenol A exposure modifies DNA methylation of imprint genes in mouse fetal germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544422699882
Pubmed

A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154448845845
Pubmed

DAZ family proteins exist throughout male germ cell development and transit from nucleus to cytoplasm at meiosis in humans and mice.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544411058556
Pubmed

AZFc partial deletions in Chilean men with severe spermatogenic failure.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544417416365
Pubmed

Dazl promotes germ cell differentiation from embryonic stem cells.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544419783541
Pubmed

Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544422293198
Pubmed

DAZL protein expression in mouse preimplantation embryo.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544417761180
Pubmed

Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544419468308
Pubmed

Partial rescue of the Dazl knockout mouse by the human DAZL gene.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544412200456
Pubmed

Nature of the spermatogenic arrest in Dazl -/- mice.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544411514340
Pubmed

Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544411089564
Pubmed

Mouse Dazl and its novel splice variant functions in translational repression of target mRNAs in embryonic stem cells.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544423298641
Pubmed

DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544422223682
Pubmed

A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544410393944
Pubmed

The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154448968756
Pubmed

A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154448968755
Pubmed

DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544430380414
Pubmed

Regulated Formation of an Amyloid-like Translational Repressor Governs Gametogenesis.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544426411291
Pubmed

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544423223451
Pubmed

Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544434985827
Pubmed

Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544411804965
Pubmed

Expression profiling of the developing testis in wild-type and Dazl knockout mice.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544414648873
Pubmed

The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154448896558
Pubmed

Evolution of the DAZ gene family suggests that Y-linked DAZ plays little, or a limited, role in spermatogenesis but underlines a recent African origin for human populations.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154449700189
Pubmed

Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-11544421270429
Pubmed

Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.

DAZ1 DAZ3 DAZ2 DAZ4

1.11e-1154448661148
Pubmed

Expression profiles of the DAZ gene family in human testis with and without spermatogenic failure.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644415066460
Pubmed

DAZL binds to the transcripts of several Tssk genes in germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644418452650
Pubmed

A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644424086306
Pubmed

DAZL binds to 3'UTR of Tex19.1 mRNAs and regulates Tex19.1 expression.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644419247806
Pubmed

DAZL is a master translational regulator of murine spermatogenesis.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644431355046
Pubmed

The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644423417416
Pubmed

The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644432170089
Pubmed

Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644416278232
Pubmed

Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644420157580
Pubmed

A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644417219433
Pubmed

Mono-butyl phthalate-induced mouse testis injury is associated with oxidative stress and down-regulated expression of Sox9 and Dazl.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644428496037
Pubmed

DAZL regulates Tet1 translation in murine embryonic stem cells.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644426077710
Pubmed

The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644416001084
Pubmed

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644432962040
Pubmed

Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644417526644
Pubmed

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-1164441869307
Pubmed

A gene family required for human germ cell development evolved from an ancient meiotic gene conserved in metazoans.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644411390979
Pubmed

BOULE, a Deleted in Azoospermia Homolog, Is Recruited to Stress Granules in the Mouse Male Germ Cells.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644427632217
Pubmed

The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-1164441638086
Pubmed

Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

3.33e-11644414611632
Pubmed

The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice.

DAZ1 CDX2 DAZ3 DAZ2 DAZ4

6.64e-112244523364048
Pubmed

Identification of two novel proteins that interact with germ-cell-specific RNA-binding proteins DAZ and DAZL1.

DAZ1 DAZ3 DAZ2 DAZ4

7.77e-11744410857750
Pubmed

The RNA-binding specificity of the mouse Dazl protein.

DAZ1 DAZ3 DAZ2 DAZ4

7.77e-11744411410654
Pubmed

Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

7.77e-11744415081113
Pubmed

Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.

DAZ1 DAZ3 DAZ2 DAZ4

7.77e-11744422699423
Pubmed

Characterization of the mouse Dazap1 gene encoding an RNA-binding protein that interacts with infertility factors DAZ and DAZL.

DAZ1 DAZ3 DAZ2 DAZ4

7.77e-11744411604102
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

DAZ1 DAZ3 DAZ2 DAZ4

7.77e-1174449588208
Pubmed

DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.

DAZ1 DAZ3 DAZ2 DAZ4

7.77e-11744426826184
Pubmed

Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.

DAZ1 DAZ3 DAZ2 DAZ4

7.77e-11744416946704
Pubmed

Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844410951504
Pubmed

Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844432339196
Pubmed

Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844433749946
Pubmed

Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844423204224
Pubmed

Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844429883445
Pubmed

A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844410823932
Pubmed

Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844422621333
Pubmed

DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844432686646
Pubmed

A preliminary report on the implication of RT-PCR detection of DAZ, RBMY1, USP9Y and Protamine-2 mRNA in testicular biopsy samples from azoospermic men.

DAZ1 DAZ3 DAZ2 DAZ4

1.55e-10844411869379
Pubmed

Maternal DNA Methylation Regulates Early Trophoblast Development.

DAZ1 CDX2 DAZ3 DAZ2 DAZ4

2.46e-102844526812015
Pubmed

Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.

DAZ1 DAZ3 DAZ2 DAZ4

2.79e-10944416310179
Pubmed

Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

2.79e-10944420159962
Pubmed

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary.

DAZ1 DAZ3 DAZ2 DAZ4

2.79e-10944426378784
Pubmed

Embryoid bodies from mouse stem cells express oxytocin receptor, Oct-4 and DAZL.

DAZ1 DAZ3 DAZ2 DAZ4

2.79e-10944419695304
Pubmed

The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.

DAZ1 DAZ3 DAZ2 DAZ4

2.79e-10944428235998
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

DAZ1 DAZ3 DAZ2 DAZ4

4.65e-101044410601091
Pubmed

Analysis of Uncharacterized mKiaa1211 Expression during Mouse Development and Cardiovascular Morphogenesis.

DAZ1 DAZ3 DAZ2 DAZ4

4.65e-101044431234534
Pubmed

Tesmin transcription is regulated differently during male and female meiosis.

DAZ1 DAZ3 DAZ2 DAZ4

4.65e-101044414648882
Pubmed

MAX controls meiotic entry in sexually undifferentiated germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

4.65e-101044438433229
Pubmed

Knockout mouse model and gametogenic failure.

DAZ1 DAZ3 DAZ2 DAZ4

4.65e-10104449922113
Pubmed

SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60.

DAZ1 DAZ3 DAZ2 DAZ4

4.65e-101044423810942
Pubmed

The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence.

DAZ1 DAZ3 DAZ2 DAZ4

4.65e-101044412837688
Pubmed

NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells.

DAZ1 DAZ3 DAZ2 DAZ4

7.30e-101144434401671
CytobandYq11.223

DAZ1 DAZ3 DAZ2 DAZ4

2.01e-0693444Yq11.223
CytobandEnsembl 112 genes in cytogenetic band chrYq11

DAZ1 DAZ3 DAZ2 DAZ4

2.26e-04311444chrYq11
CytobandXq22.1

GPRASP1 GPRASP2

7.91e-0443442Xq22.1
Cytoband11q13.2

PHOX2A SYT12

9.44e-044744211q13.2
GeneFamilyT-boxes

TBX4 TBX21

4.56e-0418322766
GeneFamilyRNA binding motif containing

DAZ1 DAZ3 DAZ2 DAZ4

5.20e-04213324725
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

GPRASP1 GPRASP2

2.62e-0343322409
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP5 ARHGAP35

3.53e-0350322721
CoexpressionTESAR_JAK_TARGETS_MOUSE_ES_D3_DN

DAZ1 DAZ3 DAZ2 DAZ4

3.08e-0912434MM742
CoexpressionSASAI_TARGETS_OF_CXCR6_AND_PTCH1_DN

DAZ1 DAZ3 DAZ2 DAZ4

3.08e-0912434MM781
CoexpressionWAGSCHAL_EHMT2_TARGETS_UP

DAZ1 DAZ3 DAZ2 DAZ4

5.43e-0823434MM1293
CoexpressionMATZUK_SPERMATOGONIA

DAZ1 DAZ3 DAZ2 DAZ4

1.91e-0731434MM765
CoexpressionCHEN_ETV5_TARGETS_TESTIS

DAZ1 DAZ3 DAZ2 DAZ4

2.48e-0733434MM701
CoexpressionMADAN_DPPA4_TARGETS

DAZ1 DAZ3 DAZ2 DAZ4

1.21e-0586434MM1312
CoexpressionJACKSON_DNMT1_TARGETS_UP

DAZ1 DAZ3 DAZ2 DAZ4

1.65e-0593434MM1185
CoexpressionGSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN

PWWP2A ANKRD40 GPRASP2 CSPG4 TBX21

1.87e-05200435M7878
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

DAZ1 PHOX2A DAZ3 DAZ2 DAZ4 LOXL1 CSPG4

3.79e-05574437MM820
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

NKX2-5 PHOX2A CDX2 LOXL1 TBX21

8.09e-05272435M1938
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

NKX2-5 PHOX2A CDX2 LOXL1 TBX21

9.58e-05282435MM822
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DMXL2 KIDINS220 CLASP1 BIRC6 AHCTF1

1.09e-061864458571956890fc9894d766ba294a28e376b4aba428
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP35 ACVRL1 TSPOAP1 TBX21

1.57e-051534440727dc70e16345645063c586d744bc4ac1710526
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENAM CSN2 CCDC34 RYR1

1.61e-051544445ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 PHOX2A TBX4 CSPG4

2.66e-05175444a7310950e8d51b3004ea3aee8ce9948fe8655112
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 PHOX2A TBX4 CSPG4

2.66e-05175444d2ff8fedca9039cbd45cfd9dec88f4edbe7fe4fc
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFB2 CCDC34 LOXL1 CSPG4

2.72e-0517644475412d58438d71c49a6096bb2ef12b7f349653d8
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DMXL2 KIDINS220 BIRC6 AHCTF1

3.30e-05185444a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
Drugboron trichloride

DAZ1 DAZ3 DAZ2 DAZ4

1.65e-106434CID000025135
Drugdazmegrel

DAZ1 ACVRL1 DAZ3 DAZ2 DAZ4

2.15e-1019435CID000053555
Drugdesmethylazelastine

DAZ1 DAZ3 DAZ2 DAZ4

1.97e-0816434CID000162558
DrugYM 026

DAZ1 DAZ3 DAZ2 DAZ4

4.19e-0819434CID000004443
DrugAZFd

DAZ1 DAZ3 DAZ2 DAZ4

9.51e-0823434CID000196489
Drugdansylaziridine

DAZ1 DAZ3 DAZ2 DAZ4

9.51e-0823434CID000104008
Drugp11-13

DAZ1 DAZ3 DAZ2 DAZ4 RYR1

2.96e-0775435CID000015759
Drugd-gluconhydroximo-1,5-lactam

DAZ1 DAZ3 DAZ2 DAZ4

3.34e-0731434CID000003479
DrugVistar

DAZ1 DAZ3 DAZ2 DAZ4

6.22e-0736434CID000040896
Drug3-bromo-7-nitroindazole

DAZ1 DAZ3 DAZ2 DAZ4

6.22e-0736434CID000001649
DrugBW755C

DAZ1 ACVRL1 DAZ3 DAZ2 DAZ4

8.68e-0793435CID000047795
Drugmolybdenum disulfide

DAZ1 DAZ3 DAZ2 DAZ4

1.29e-0643434CID000014823
Drug2-chlorodideoxyadenosine

DAZ1 DAZ3 DAZ2 DAZ4

1.29e-0643434CID000072194
Drugpropham

DAZ1 DAZ3 DAZ2 DAZ4

1.42e-0644434CID000024685
DrugDesipramine hydrochloride [58-28-6]; Up 200; 13.2uM; PC3; HT_HG-U133A

TGFB2 ZNF609 ARHGAP35 TSPOAP1 RYR1 CSPG4

1.52e-061914366693_UP
Drugridogrel

DAZ1 DAZ3 DAZ2 DAZ4

2.79e-0652434CID005362391
DrugTXB2 (thromboxane B2

DAZ1 ACVRL1 DAZ3 DAZ2 DAZ4

2.82e-06118435CID000005461
Drugthromboxane

TGFB2 DAZ1 ACVRL1 DAZ3 DAZ2 DAZ4

3.72e-06223436CID000114873
Drugazafagomine

DAZ1 DAZ3 DAZ2 DAZ4

4.05e-0657434CID011957435
DrugNSC56408

DAZ1 DAZ3 DAZ2 DAZ4

5.68e-0662434CID000005604
Drugkt S

DAZ1 DAZ3 DAZ2 DAZ4

7.30e-0666434CID006399216
Drugazelastine

DAZ1 DAZ3 DAZ2 DAZ4

1.15e-0574434CID000002267
Drugbipy

DAZ1 DAZ3 DAZ2 DAZ4

3.36e-0597434CID000001474
DrugNabumetone [42924-53-8]; Up 200; 17.6uM; MCF7; HT_HG-U133A

ZNF609 KIDINS220 ACVRL1 RYR1 CSPG4

3.48e-051984356487_UP
Drugcarbonyl sulfide

DAZ1 DAZ3 DAZ2 DAZ4

6.77e-05116434CID000010039
DrugFLA 365

LOXL1 RYR1

1.24e-049432CID000072776
DiseaseMale sterility due to Y-chromosome deletions

DAZ1 DAZ3 DAZ2 DAZ4

2.72e-108434C2931163
DiseasePartial chromosome Y deletion

DAZ1 DAZ3 DAZ2 DAZ4

2.72e-108434C1507149
DiseaseSpermatogenic failure, Y-linked, 2

DAZ1 DAZ3 DAZ2

1.59e-0616433cv:C1839071
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

DAZ1 DAZ3 DAZ2

1.59e-0616433C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

DAZ1 DAZ3 DAZ2

1.59e-0616433415000
DiseaseMultiminicore myopathy

SELENON RYR1

2.07e-062432cv:C0270962
Diseaseosteochondrodysplasia (biomarker_via_orthology)

TGFB2 RYR1

2.07e-062432DOID:2256 (biomarker_via_orthology)
Diseasehypoplastic left heart syndrome (implicated_via_orthology)

NKX2-5 SAP130

2.07e-062432DOID:9955 (implicated_via_orthology)
DiseaseRare disease with malignant hyperthermia

SELENON RYR1

1.24e-054432cv:C5681128
DiseaseHypoplastic Left Heart Syndrome

NKX2-5 SAP130

2.07e-055432C0152101
DiseaseCongenital myopathy with fiber type disproportion

SELENON RYR1

3.10e-056432cv:C0546264
DiseaseFamilial pulmonary arterial hypertension

TBX4 ACVRL1

5.78e-058432C1701939
DiseasePulmonary arterial hypertension

TBX4 ACVRL1

9.27e-0510432C2973725
DiseaseCongenital myopathy (disorder)

SELENON RYR1

1.36e-0412432C0270960
DiseaseCongenital muscular dystrophy

SELENON RYR1

1.36e-0412432cv:C0699743
DiseaseAutosomal Dominant Myotubular Myopathy

SELENON RYR1

1.60e-0413432C3661489
DiseaseCentronuclear myopathy

SELENON RYR1

1.60e-0413432C0175709
DiseaseCongenital Structural Myopathy

SELENON RYR1

1.60e-0413432C0752282
DiseaseX-linked centronuclear myopathy

SELENON RYR1

1.60e-0413432C0410203
DiseaseMyopathy, Centronuclear, 1

SELENON RYR1

1.60e-0413432C4551952
DiseaseMyopathy, Centronuclear, Autosomal Dominant

SELENON RYR1

1.87e-0414432C1834558
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

TBX4 ACVRL1

1.87e-0414432C1150929
DiseaseTubular Aggregate Myopathy

SELENON RYR1

1.87e-0414432C0410207
DiseaseAutosomal Recessive Centronuclear Myopathy

SELENON RYR1

2.15e-0415432C3645536
DiseaseIdiopathic pulmonary arterial hypertension

TBX4 ACVRL1

2.46e-0416432C3203102
DiseaseFamilial primary pulmonary hypertension

TBX4 ACVRL1

2.78e-0417432C0340543
DiseaseCongenital Fiber Type Disproportion

SELENON RYR1

3.13e-0418432C0546264
Diseasesmoking behavior, BMI-adjusted waist circumference

TGFB2 TBX4 LOXL1

7.54e-04122433EFO_0004318, EFO_0007789
DiseaseBMI-adjusted waist circumference, physical activity measurement

TGFB2 TBX4 LOXL1

7.72e-04123433EFO_0007789, EFO_0008002

Protein segments in the cluster

PeptideGeneStartEntry
LAPQNFVSPPQYPDY

CDX2

26

Q99626
YFPQDYPSSPPLVNL

BIRC6

4631

Q9NR09
RVTAPPYFSPLYTFP

CSPG4

876

Q6UVK1
YRPPFYDVVPNDPSF

ACVRL1

421

P37023
PNYLANPAFPFIYTP

ANKRD40

121

Q6AI12
FFQPSQGYRPPPFSE

DMXL2

876

Q8TDJ6
SYIPFVQPNYPYPQR

C1orf94

531

Q6P1W5
YNYQPFPAYPRSPFQ

DAZ2

211

Q13117
YQPFPAYPSSPFQVT

DAZ2

261

Q13117
YNYQPFPAYPRSPFQ

DAZ3

211

Q9NR90
YQPFPAYPSSPFQVT

DAZ3

261

Q9NR90
RYSYNPFEGPNENPE

TSPOAP1

661

O95153
PQHPFYNRPFFAPYL

KIDINS220

1131

Q9ULH0
FYFPPMYSPQQQFPL

LARP4B

341

Q92615
PSYPQQFPYPQAPFV

LOXL1

171

Q08397
NVYPELYPSEPRPSF

GALNT15

491

Q8N3T1
FPAAPAFYPRAYSDP

NKX2-5

86

P52952
ESQSFYPEAYQGPPV

PASD1

636

Q8IV76
YNYQPFPAYPRSPFQ

DAZ1

541

Q9NQZ3
YQPFPAYPSSPFQVT

DAZ1

591

Q9NQZ3
SGNSYPEPAFYNPIP

CCDC34

306

Q96HJ3
DFPFPEDYPNYVPNS

FMO1

71

Q01740
YPSFQPQPLIYPFVE

CSN2

56

P05814
PEYNPYDPRENSPYL

ENAM

601

Q9NRM1
PSYPPPEQFFNPSTY

AHCTF1

461

Q8WYP5
YNYQPFPAYPRSPFQ

DAZ4

376

Q86SG3
YQPFPAYPSSPFQVT

DAZ4

426

Q86SG3
AQTYDPREGYNPQPP

RYR1

2846

P21817
PYYQLQPESPLPEAF

SLC7A3

311

Q8WY07
QPSPEFPFQYDPSYR

GPRASP1

1106

Q5JY77
GSFPSPSPFPNYDYR

SYT12

46

Q8IV01
PYPPPLFIRDTYNQS

PWWP2A

271

Q96N64
PDQPSPEFTFQYDPS

GPRASP2

546

Q96D09
QTPDPTAPVAYFPYF

SHPK

296

Q9UHJ6
LPSPRDCFPYNNYPD

ARHGAP5

966

Q13017
DTFMQYFYGQPPPPT

TEX45

326

Q8NA69
PTQTPEELAFYAPNY

PMIS2

56

A0A1W2PS18
QCPFFFYNRPITEPP

ARHGAP35

1431

Q9NRY4
PQDFPFYYLQQGSRP

EXTL1

401

Q92935
FPGPRARDYNPYPYS

CLASP1

1256

Q7Z460
FFPSENAIPPTFYRP

TGFB2

111

P61812
QPRNVPNRYTFPCPY

RNF114

131

Q9Y508
QPAPYSAVPYKFFPE

PHOX2A

66

O14813
FTGYLSNNRFYPPPP

SELENON

231

Q9NZV5
VPVQFQYFLPTYPPS

SAP130

481

Q9H0E3
PPQPQSKDSPYYQGF

ZNF609

881

O15014
VDPQNTLPSFYPPYS

USF3

2101

Q68DE3
YFRSPPPYDQQMLSP

TBX4

366

P57082
NQYPVPSRFYPDLPG

TBX21

361

Q9UL17