Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionheat shock protein binding

GBP3 UNC45A DNAJB9 METTL23 SLC12A2 PPP5C CLTC STIP1

1.05e-041631778GO:0031072
GeneOntologyMolecularFunctionHsp90 protein binding

GBP3 UNC45A SLC12A2 PPP5C STIP1

1.26e-04551775GO:0051879
GeneOntologyCellularComponentclathrin coat of trans-Golgi network vesicle

CLTCL1 AP2A1 AP1B1 CLTC

1.42e-05181784GO:0030130
GeneOntologyCellularComponenttrans-Golgi network transport vesicle membrane

CLTCL1 AP2A1 AP1B1 CLTC

3.30e-05221784GO:0012510
GeneOntologyCellularComponentGolgi-associated vesicle membrane

CLTCL1 AP2A1 AP1B1 CLTC CNGA4

1.71e-04611785GO:0030660
GeneOntologyCellularComponentclathrin vesicle coat

CLTCL1 AP2A1 AP1B1 CLTC

2.99e-04381784GO:0030125
GeneOntologyCellularComponenttrans-Golgi network transport vesicle

CLTCL1 AP2A1 AP1B1 CLTC

3.66e-04401784GO:0030140
DomainARM-type_fold

CLTCL1 IFT172 MROH2A UBR4 MROH5 ARFGEF2 APOB UNC45A MEI1 RALGAPA2 EFR3A AP2A1 AP1B1 PIK3C2A CLTC UTP20

9.49e-0833917116IPR016024
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

8.33e-0521712IPR022365
DomainClathrin-link

CLTCL1 CLTC

8.33e-0521712PF09268
Domain-

CLTCL1 CLTC

8.33e-05217122.130.10.110
DomainClathrin_heavy_chain

CLTCL1 CLTC

8.33e-0521712IPR016341
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

8.33e-0521712IPR001473
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

8.33e-0521712IPR016025
DomainClathrin_propel

CLTCL1 CLTC

8.33e-0521712PF01394
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

8.33e-0521712IPR015348
DomainClathrin_H-chain_linker

CLTCL1 CLTC

2.49e-0431712IPR012331
DomainOest-rel_rcp

ESRRB ESRRG

2.49e-0431712IPR027289
DomainCLH

CLTCL1 CLTC

2.49e-0431712SM00299
DomainTPR-like_helical_dom

CLTCL1 IFT172 UNC45A PPP5C CLTC PDCD11 STIP1 CDC27 SMG6

3.04e-042331719IPR011990
DomainNebulin

NEBL NEB

4.94e-0441712PF00880
DomainNEBULIN

NEBL NEB

4.94e-0441712PS51216
DomainNEBU

NEBL NEB

4.94e-0441712SM00227
DomainNebulin

NEBL NEB

4.94e-0441712IPR013998
DomainNebulin_repeat

NEBL NEB

4.94e-0441712IPR000900
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CERK SPAM1 EP400 MAP1A UACA VWA8 ABCA12 HMGXB4 RALGAPA2 SIRT1 NSD3 NCOR2 NAA35 GTF2H1 PBRM1 KMT5B CHD5 PIP4K2A USP7 FMN2 PIP4K2B ZFHX3 ADAM17 KDM1B CDC27 EP300 ARAP2

2.92e-1111161802731753913
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

NEBL EP400 UACA HMGXB4 UNC45A TTF1 ESF1 NSD3 EFR3A METAP1 GTF2H1 CEPT1 PBRM1 SHANK2 SLC12A2 PIK3C2A PHF3 UBP1 USP7 PDCD11 CRYBG1 UTP20 ZFHX3 STIP1 EIF3A EIF3F KDM1B CDC27 ZHX1 SF3A2 SMG6

4.28e-1114971803131527615
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

VAPB DMXL2 MAP1A SHANK3 PTK2B SHANK2 AP2A1 AP1B1 PHF3 GNA13 CLTC STIP1 RIMS2

3.06e-092811801328706196
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

HMGXB4 ARHGAP11A SGO1 ZEB2 SIRT1 NSD3 PBRM1 THYN1 FAM50A PHF3 UBTF GLYR1 CHD5 USP7 KDM1B CDC27 ZHX1

2.16e-086081801736089195
Pubmed

Human transcription factor protein interaction networks.

ERCC4 EP400 RBM10 UBR4 HMGXB4 LARP1 SPAG9 SPATA2 ZEB2 SIRT1 NCOR2 PBRM1 UBTF GLYR1 CHD5 SYNE2 USP7 PDCD11 ZFHX3 STIP1 EIF3A EIF3F KDM1B ZHX1 EP300 FILIP1L

2.66e-0814291802635140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

VAPB MYH6 CLTCL1 UBR4 LARP1 ATP10B APOB NEB SGO1 CXorf65 ZEB2 ESF1 LIG4 SHANK2 AP2A1 FAM50A GNA13 CHD5 SYNE2 PIP4K2A CLTC PIP4K2B EIF3A RIMS2 CDC27 SF3A2

3.18e-0814421802635575683
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

UACA EXPH5 LARP1 UNC45A ITGA4 ARHGAP11A IFI16 ESF1 NSD3 GTF2H1 AP2A1 PHF3 UBTF GLYR1 CHD5 CLTC USP7 CSTA PDCD11 CRYBG1 UTP20 EIF3A EIF3F SF3A2

3.95e-0812571802436526897
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

VAPB DMXL2 UACA VWA8 UBR4 MRPL45 UNC45A DNAJB9 SIRT1 ESF1 EFR3A NAA35 SLC12A2 PPP5C PIK3C2A UBTF GLYR1 ASNS SYNE2 CLTC PDCD11 TMEM131 STIP1 DNAJB5 GPAT4 GOLGA3

5.84e-0814871802633957083
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ANXA6 UBR4 LARP1 SPAG9 TTF1 ESF1 PBRM1 AP1B1 PHF3 UBTF GLYR1 ASNS SYNE2 CLTC USP7 PDCD11 UTP20

6.04e-086531801722586326
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CACNA1F EPB41L4B UBR4 LARP1 SPAG9 ARHGAP11A ZNF831 CHN1 FAM186B THYN1 ASNS CLTC FMN2 UTP20 STIP1 EIF3A CFAP44 ELP4

6.19e-087361801829676528
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

PDGFRA ESRRG UBR4 HMGCR DNAJB9 METTL23 SMC5 PAPSS2 FAM186B SIRT1 ESF1 NAA35 CEPT1 PBRM1 KMT5B FAM50A UBP1 UBTF GNA13 CLTC USP7 STIP1 CDC25A EP300

1.08e-0713271802432694731
Pubmed

The protein interaction landscape of the human CMGC kinase group.

CABLES2 EP400 PDGFRA ZRSR2 ESRRG LARP1 ZNF510 NEB SIRT1 GTF2H1 SHANK2 PPP5C PHF3 USP7 PDCD11 STIP1 EP300

1.46e-076951801723602568
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EP400 RASA2 UBR4 UNC45A PAPSS2 IFI16 ESF1 NCOR2 NAA35 GTF2H1 AP2A1 PIK3C2A UBTF GLYR1 ASNS PIP4K2A CLTC USP7 CSTA PDCD11 UTP20 EIF3A EIF3F CDC27

1.53e-0713531802429467282
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

ERCC4 EP400 ARHGAP11A ZEB2 NCOR2 USP7 HSF2 ZHX1

1.74e-07116180830804394
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

EP400 LARP1 MRPL45 IDE ZEB2 NCOR2 PBRM1 UBP1 SYNE2 PIP4K2A USP7 STIP1 EP300

1.82e-073981801335016035
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DMXL2 ZRSR2 FOLH1 IFT172 UBR4 ARFGEF2 ZNF227 DNAJB9 ZEB2 ITGB8 METAP1 PPP5C AP2A1 VPS35L USP32 CLTC USP7 FMN2 TMEM131 EIF3F SF3A2 EP300 GOLGA3

2.44e-0712851802335914814
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

VAPB VWA8 MRPL45 UNC45A SPATA2 SIRT1 PPP5C PIK3C2A GNA13 USP32 USP7 CSTA STIP1 EIF3A MPHOSPH9 EIF3F KDM1B CDC25A CDC27 SF3A2

3.06e-0710051802019615732
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

EP400 UBR4 UNC45A SMC5 IFI16 SIRT1 ESF1 NSD3 NCOR2 PBRM1 FAM50A PHF3 UBTF ASNS USP7 EIF3A EIF3F KDM1B SF3A2 EP300

3.52e-0710141802032416067
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

VAPB CLTCL1 UACA VWA8 ANXA6 UBR4 LARP1 HMGCR MRPL45 UNC45A ARHGAP11A IFI16 PIK3C2A UBTF ASNS SYNE2 VPS35L CLTC USP7 CSTA PDCD11 STIP1 EIF3A EIF3F

4.71e-0714401802430833792
Pubmed

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2.

CLTCL1 AP2A1 CLTC

5.43e-074180311517213
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

EP400 UBR4 HMGXB4 LARP1 SPAG9 MRPL45 TTF1 ZEB2 NCOR2 LIG4 UBP1 GLYR1 CSTA UTP20 KDM1B CDC25A CDC27 EP300

5.75e-078571801825609649
Pubmed

Defining the membrane proteome of NK cells.

PPP1R21 CLTCL1 PDGFRA ANXA6 UBR4 ARFGEF2 LARP1 ITGA4 IFI16 NCOR2 AP2A1 PIK3C2A GNA13 CHD5 CLTC ADAM17 EIF3A MPHOSPH9 EIF3F GPAT4 GOLGA3

7.89e-0711681802119946888
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ENOSF1 CABLES2 FUT10 RASA2 UACA EPB41L4B FOLH1 ANXA6 LARP1 IDE TTF1 GRHL2 NAALADL2 KRCC1 NCOR2 FAM111A SHANK2 GLYR1 VPS35L ZFHX3 ZNF839 CYP4F11 EP300 SMG6

8.52e-0714891802428611215
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

LARP1 ATP10B SPATA2 FCHSD2 RHOBTB2 RIMS2 SMG6

1.01e-0610118079872452
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

VAPB PPP1R21 DMXL2 ANXA6 UBR4 NEB GBA2 AP1B1 SYNE2 USP32 EIF3A

1.06e-063221801126514267
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

VAPB EP400 RBM10 HMGXB4 ARHGAP11A IFI16 TTF1 NSD3 NCOR2 PBRM1 AP2A1 PHF3 UBP1 UBTF GLYR1 USP7 PDCD11 UTP20 KDM1B CDC27 SF3A2 EP300

1.07e-0612941802230804502
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

EXOC6 RASA2 ANXA6 UBR4 IDE ZNF227 NEB ESF1 MEPE NCOR2 PBRM1 AP1B1 UBP1 SYNE2 EP300

1.33e-066381801531182584
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CABLES2 MYH6 TRAF1 UACA ESF1 PTK2B NCOR2 NEK3 GTF2H1 AP2A1 AP1B1 NRK PIP4K2A USP7 PIP4K2B EIF3F CDC27 EP300

1.35e-069101801836736316
Pubmed

Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.

CLTCL1 AP2A1 CLTC

1.35e-065180310436022
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

UACA LARP1 IFI16 ESF1 PBRM1 UBTF GLYR1 PIP4K2A USP7 PDCD11 UTP20

1.43e-063321801125693804
Pubmed

Tagging genes with cassette-exchange sites.

VAPB UBR4 ARFGEF2 LARP1 SIRT1 PHAF1 NCOR2 UBP1 PIP4K2B TMEM131 SMG6

1.56e-063351801115741177
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

KANSL1L DMXL2 MYOM1 UACA ESRRG NEB PPP5C PIK3C2A SYNE2 CLTC STIP1 EIF3A DNAJB5

2.18e-064971801323414517
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

RBM10 GRHL2 NCOR2 PBRM1 UBTF USP7 ZFHX3 STIP1 EP300

2.41e-06220180935785414
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

VAPB SPAG9 IDE SGO1 ESF1 NSD3 EFR3A NCOR2 SLC12A2 PPP5C UBTF GLYR1 SYNE2 CLTC USP7 FMN2 STIP1 MPHOSPH9 CDC25A

2.46e-0610491801927880917
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

ERCC4 EP400 ARHGAP11A SIRT1 ESF1 AP2A1 AP1B1 UBTF PDCD11

2.60e-06222180937071664
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

VAPB EP400 UACA VWA8 ANXA6 LARP1 APOB UNC45A DNAJB9 TTF1 PBRM1 FAM111A THYN1 AP2A1 AP1B1 PIK3C2A FAM50A PHF3 GLYR1 CLTC CSTA PDCD11

2.73e-0613711802236244648
Pubmed

Functional proteomics mapping of a human signaling pathway.

EXPH5 UBR4 ARFGEF2 ZNF510 UNC45A TTF1 ZEB2 METAP1 NCOR2 PBRM1 AP2A1 AP1B1 EIF3F SF3A2

2.79e-065911801415231748
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

EP400 ESRRB GRHL2 PHF3 UBP1 USP7 CDC27 SF3A2

4.26e-06177180826206133
Pubmed

Clathrin interacts specifically with amphiphysin and is displaced by dynamin.

AP2A1 AP1B1 CLTC

4.70e-06718039280305
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

VAPB ERCC4 EP400 RBM10 SMC5 IFI16 GTF2H1 FAM111A PHF3 KDM1B ZHX1 EP300

4.77e-064531801229656893
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

VAPB TRAF1 ANXA6 UBR4 LARP1 APOB IDE UNC45A ESF1 PBRM1 PPP5C AP2A1 UBTF GLYR1 ASNS CLTC USP7 CSTA PDCD11 UTP20 STIP1 EIF3A

5.05e-0614251802230948266
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RIN3 CLTCL1 EP400 VWA8 UBR4 ARFGEF2 RALGAPA2 GBA2 NSD3 NCOR2 SHANK2 AP2A1 CHD5 USP7 PDCD11 ZNF839 GPAT4 EP300 SMG6

5.19e-0611051801935748872
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

VAPB CLTCL1 UBR4 LARP1 GBP3 PAPSS2 NAA35 SLC12A2 AP2A1 AP1B1 CLTC USP7 ZFHX3 STIP1 EIF3A EIF3F

5.21e-068071801630575818
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

EP400 RBM10 LARP1 SPAG9 UNC45A ESF1 NSD3 PHF3 CLTC USP7 PDCD11 EP300 ELP4

6.41e-065491801338280479
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

EP400 SPAG9 ARHGAP11A SGO1 NSD3 PBRM1 AP2A1 FAM50A GLYR1 PIP4K2A PIP4K2B MPHOSPH9 KDM1B EP300

7.54e-066451801425281560
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

VAPB NEBL UACA EPB41L4B LARP1 UNC45A EFR3A SHANK2 SLC12A2 CRYBG1 ADAM17 ELP4 GOLGA3

8.70e-065651801325468996
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

UACA EPB41L4B EXPH5 ARFGEF2 APOB RALGAPA2 EFR3A FRMD4A SLC12A2 NRK USP32 FMN2 ARAP2

9.38e-065691801330639242
Pubmed

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.

CLTCL1 AP2A1 PIK3C2A CLTC

9.49e-0626180424067654
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RBM10 LARP1 UNC45A IFI16 NSD3 CEPT1 PBRM1 PHF3 UBP1 UBTF GLYR1 PDCD11 UTP20 EIF3A EIF3F SF3A2

9.51e-068471801635850772
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EP400 IFT172 RBM10 SMC5 SPATA2 ZEB2 FCHSD2 PHF3 RHOBTB2 CLTC ARAP2

9.94e-064071801112693553
Pubmed

Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.

AP2A1 AP1B1 CLTC

1.12e-059180312429846
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

VAPB IMPA1 UBR4 APOB DNAJB9 CEPT1 AP2A1 GLYR1 USP7 DNAJB5 GPAT4 EP300

1.26e-054991801222810586
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

EP400 UACA RBM10 ARFGEF2 LARP1 SPAG9 IFI16 SIRT1 ESF1 NCOR2 PHF3 CLTC USP7 UTP20 ZHX1

1.35e-057741801515302935
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

VAPB DMXL2 ARFGEF2 SLC12A2 SYNE2 VPS35L USP32 FMN2 TMEM131 ADAM17 GPAT4 GOLGA3

1.39e-055041801234432599
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

DMXL2 EP400 MAP1A VWA8 ZRSR2 RBM10 ANXA6 HMGXB4 MRPL45 NSD3 THYN1 AP2A1 GLYR1 CLTC USP7 EIF3F KDM1B SF3A2

1.45e-0510821801838697112
Pubmed

Characterization of gene expression in mouse blastocyst using single-pass sequencing of 3995 clones.

ESF1 CSTA PDCD11

1.59e-051018039598303
Pubmed

Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.

SIRT1 USP7 EP300

1.59e-0510180328196907
Pubmed

CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.

CLTCL1 AP2A1 CLTC

1.59e-0510180325898166
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

PDGFRA RBM10 ARHGAP11A ESF1 METAP1 NCOR2 GTF2H1 PHF3 UBTF GLYR1 CLTC USP7 PDCD11 UTP20 EIF3A EIF3F SF3A2

1.67e-059891801736424410
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

EP400 MAP1A LARP1 SPAG9 IFI16 NCOR2 FAM50A PHF3 USP7 CSTA EIF3F

2.22e-054441801134795231
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

PDGFRA ZEB2 NSD3 FRMD4A PBRM1 UBTF

2.30e-05109180633554859
Pubmed

Generation and analysis of 280,000 human expressed sequence tags.

CACNA1F ESRRG SPATA2 HELQ CXorf65 PHAF1 PBRM1 HP CCNB1IP1 EP300

2.42e-05368180108889549
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DMXL2 SPAG9 SMC5 PHF3 RHOBTB2 CHD5 SYNE2 SMG6

2.44e-05225180812168954
Pubmed

ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.

ZDHHC11B ZDHHC11

2.66e-052180228331227
Pubmed

Expression of estrogen-related receptors in ovarian cancer and impact on survival.

ESRRB ESRRG

2.66e-052180234089362
Pubmed

A meta-analysis of Italian and Estonian individuals shows an effect of common variants in HMGCR on blood apoB levels.

APOB HMGCR

2.66e-052180230191727
Pubmed

Expression of a novel TGIF subclass homeobox gene, Tex1, in the spermatids of mouse testis during spermatogenesis.

TGIF2LY TGIF2LX

2.66e-052180211960710
Pubmed

Differentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice.

SHANK3 SHANK2

2.66e-052180233126897
Pubmed

SIRT1 mediates breast cancer development and tumorigenesis controlled by estrogen-related receptor β.

ESRRB SIRT1

2.66e-052180238421553
Pubmed

The interferon-inducible nucleolar p204 protein binds the ribosomal RNA-specific UBF1 transcription factor and inhibits ribosomal RNA transcription.

IFI16 UBTF

2.66e-052180210329630
Pubmed

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.

SHANK3 SHANK2

2.66e-052180222699619
Pubmed

Activation and overexpression of Sirt1 attenuates lung fibrosis via P300.

SIRT1 EP300

2.66e-052180228365154
Pubmed

Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.

SHANK3 SHANK2

2.66e-052180231052177
Pubmed

Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.

PIP4K2A PIP4K2B

2.66e-052180229727621
Pubmed

Testis-specific hnRNP is expressed in colorectal cancer cells and accelerates cell growth mediating ZDHHC11 mRNA stabilization.

ZDHHC11B ZDHHC11

2.66e-052180235384384
Pubmed

Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.

SHANK3 SHANK2

2.66e-052180227199660
Pubmed

Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.

NEBL NEB

2.66e-052180219851499
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

2.66e-05218028733129
Pubmed

HAUSP stabilizes Cdc25A and protects cervical cancer cells from DNA damage response.

USP7 CDC25A

2.66e-052180232860838
Pubmed

Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development.

SHANK3 SHANK2

2.66e-052180210506216
Pubmed

Cigarette smoke extract mediates cell premature senescence in chronic obstructive pulmonary disease patients by up-regulating USP7 to activate p300-p53/p21 pathway.

USP7 EP300

2.66e-052180235114313
Pubmed

Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme.

CERK ADAM17

2.66e-052180222009748
Pubmed

A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.

GLYR1 KDM1B

2.66e-052180230970244
Pubmed

G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription.

PTK2B GNA13

2.66e-052180210821841
Pubmed

Association of TGIFLX/Y mRNA expression with prostate cancer.

TGIF2LY TGIF2LX

2.66e-052180218663611
Pubmed

The human-specific Yp11.2/Xq21.3 homology block encodes a potentially functional testis-specific TGIF-like retroposon.

TGIF2LY TGIF2LX

2.66e-052180212226713
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

2.66e-052180229097553
Pubmed

Association of TGIFLX/Y mRNA expression with azoospermia in infertile men.

TGIF2LY TGIF2LX

2.66e-052180218384077
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

2.66e-052180220065094
Pubmed

Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR.

ESRRB ESRRG

2.66e-052180210072763
Pubmed

Involvement of TACE in colon inflammation: a novel mechanism of regulation via SIRT-1 activation.

SIRT1 ADAM17

2.66e-052180224548422
Pubmed

Transcriptional Coactivator p300 and Silent Information Regulator 1 (SIRT1) Gene Polymorphism Associated with Diabetic Kidney Disease in a Chinese Cohort.

SIRT1 EP300

2.66e-052180228444663
Pubmed

An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells.

ESRRB ESRRG

2.66e-052180219631715
Pubmed

Expression profiles of the autism-related SHANK proteins in the human brain.

SHANK3 SHANK2

2.66e-052180237953224
Pubmed

Shank2/3 double knockout-based screening of cortical subregions links the retrosplenial area to the loss of social memory in autism spectrum disorders.

SHANK3 SHANK2

2.66e-052180236100669
Pubmed

Sirt1 Negatively Regulates Cellular Antiviral Responses by Preventing the Cytoplasmic Translocation of Interferon-Inducible Protein 16 in Human Cells.

IFI16 SIRT1

2.66e-052180236749073
Pubmed

Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system.

SHANK3 SHANK2

2.66e-052180220800661
Pubmed

LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation.

GLYR1 KDM1B

2.66e-052180223260659
Pubmed

SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis.

SHANK3 SHANK2

2.66e-052180236845137
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MAP1A UACA EPB41L4B ESRRB ESRRG LARP1 SMC5 PHAF1 PIK3C2A FAM50A PHF3 PIP4K2A TMEM131 CDC27

2.71e-057241801436232890
InteractionWNK3 interactions

CLTCL1 AP2A1 AP1B1 PIK3C2A CLTC USP7 EIF3A

6.00e-07561787int:WNK3
InteractionH3-3A interactions

PDGFRA HMGXB4 SPAG9 ITGA4 ARHGAP11A SMC5 SGO1 ZEB2 SIRT1 NSD3 PBRM1 THYN1 FAM50A PHF3 UBTF GLYR1 CHD5 USP7 KDM1B CDC27 ZHX1 EP300

8.09e-0774917822int:H3-3A
InteractionAGAP2 interactions

VAPB MAP1A SHANK3 PTK2B SHANK2 AP2A1 AP1B1 PHF3 GNA13 CLTC RIMS2

2.76e-0621017811int:AGAP2
InteractionSOX4 interactions

EP400 SPAG9 MINPP1 NSD3 PBRM1 EP300 FILIP1L

4.88e-06761787int:SOX4
InteractionSUMO2 interactions

TRAF1 ERCC4 EP400 UBR4 HMGXB4 SMC5 SIRT1 PBRM1 PHF3 ASNS CLTC USP7 STIP1 CCNB1IP1 HSF2 ZHX1 EP300

2.04e-0559117817int:SUMO2
InteractionAR interactions

EP400 FOLH1 EXPH5 RBM10 LARP1 IDE IFI16 GRHL2 SIRT1 NCOR2 GTF2H1 PBRM1 PPP5C PHF3 UBTF ASNS CLTC USP7 ZFHX3 STIP1 CDC25A CDC27 EP300

2.24e-0599217823int:AR
InteractionH3C3 interactions

HMGXB4 ITGA4 ARHGAP11A SGO1 ZEB2 NSD3 PBRM1 THYN1 FAM50A PHF3 UBTF GLYR1 CHD5 KDM1B CDC27

3.53e-0549517815int:H3C3
InteractionSNAP91 interactions

CLTCL1 SMC5 SHANK3 AP1B1 ASNS CLTC

3.58e-05701786int:SNAP91
InteractionNUP43 interactions

EP400 LARP1 SGO1 IFI16 TTF1 NSD3 NCOR2 PBRM1 UBTF GLYR1 SYNE2 PDCD11 UTP20 ZFHX3 HSF2 ZHX1 ELP4

4.11e-0562517817int:NUP43
InteractionFBXO38 interactions

ERCC4 EP400 ARHGAP11A ZEB2 NCOR2 USP7 HSF2 ZHX1

4.51e-051451788int:FBXO38
InteractionADAR interactions

RIN3 EP400 RBM10 SMC5 IFI16 GLYR1 CHD5 CLTC USP7 STIP1 EP300

4.97e-0528617811int:ADAR
InteractionBRD1 interactions

MYH6 MAP1A VWA8 IFI16 SIRT1 NCOR2 PBRM1 PPP5C KMT5B CHD5 CLTC CDC27

5.80e-0534417812int:BRD1
InteractionSGIP1 interactions

SHANK3 NCOR2 AP2A1 AP1B1 CRYBG1

7.80e-05501785int:SGIP1
InteractionPIP4K2C interactions

RASA2 LARP1 SHANK3 UBTF PIP4K2A CLTC USP7 PIP4K2B

8.63e-051591788int:PIP4K2C
InteractionPPP2R1A interactions

RIN3 CLTCL1 EP400 ESRRB LARP1 SPAG9 ITGA4 SGO1 IFI16 EFR3A PPP5C RHOBTB2 CLTC USP7 STIP1 HSF2 EP300

8.81e-0566517817int:PPP2R1A
InteractionDDX23 interactions

CERK RBM10 SPAG9 IFI16 ESF1 FAM50A PHF3 UBTF PIP4K2A PDCD11 PIP4K2B UTP20 SF3A2 EP300

9.70e-0548017814int:DDX23
InteractionARX interactions

APOB AP2A1 PIK3C2A CLTC

1.02e-04281784int:ARX
InteractionPAX6 interactions

EP400 ESRRG APOB GRHL2 SHANK3 ZEB2 NCOR2 PBRM1 GLYR1 ZFHX3 ZHX1 EP300

1.05e-0436617812int:PAX6
InteractionPENK interactions

USP7 CCNB1IP1 CDC27

1.06e-04111783int:PENK
InteractionSIRT7 interactions

ANXA6 UBR4 LARP1 SPAG9 TTF1 SIRT1 ESF1 PBRM1 AP1B1 PHF3 UBTF GLYR1 ASNS SYNE2 CLTC USP7 PDCD11 UTP20

1.09e-0474417818int:SIRT7
InteractionRPL7A interactions

RIN3 EPB41L4B RBM10 ANXA6 ITGA4 SGO1 IFI16 TTF1 SIRT1 METAP1 NAA35 FAM111A GLYR1 ASNS SYNE2 USP7 STIP1

1.13e-0467917817int:RPL7A
InteractionPOLR1G interactions

EP400 UBR4 TTF1 ZEB2 ESF1 NSD3 PBRM1 FAM50A PHF3 UBTF CLTC USP7 PDCD11 UTP20

1.18e-0448917814int:POLR1G
InteractionACSM5 interactions

VWA8 UBR4 SERPINA10 EP300 MMUT

1.24e-04551785int:ACSM5
InteractionLYAR interactions

ERCC4 ESRRB SMC5 IFI16 TTF1 FAM111A UBTF GLYR1 PIP4K2A EIF3A ZHX1 EP300

1.25e-0437317812int:LYAR
InteractionITGB3 interactions

PDGFRA UBR4 ITGA4 PTK2B AP1B1 CLTC USP7 EIF3A

1.37e-041701788int:ITGB3
InteractionCSNK2B interactions

RIN3 EP400 ARFGEF2 ITGA4 SMC5 IFI16 SHANK3 ZEB2 SIRT1 ESF1 PIP4K2A STIP1 EIF3F ZHX1 EP300 SMG6

1.41e-0462517816int:CSNK2B
InteractionH3C1 interactions

UBR4 HMGXB4 LARP1 SPAG9 ITGA4 NEB ARHGAP11A SMC5 SIRT1 NSD3 PBRM1 FAM50A PHF3 UBTF GLYR1 USP7 ZFHX3 KDM1B CDC27 EP300

1.44e-0490117820int:H3C1
InteractionH2BC21 interactions

RIN3 EP400 HMGXB4 NEB IFI16 TTF1 NSD3 ADHFE1 PBRM1 PHF3 GLYR1 USP7 CRYBG1 MICA KDM1B CDC27 EP300

1.52e-0469617817int:H2BC21
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZEB2 ZFHX3 ZHX1

1.05e-04151143529
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TPST1 DMXL2 HMGXB4 SPAG9 ARHGAP11A SMC5 ZEB2 EFR3A NCOR2 FCHSD2 PIK3C2A PHF3 SYNE2 PIP4K2A USP7 UTP20 ZFHX3 TMEM131 ADAM17 EIF3A MPHOSPH9 CDC27 ARAP2 FILIP1L

4.92e-0985617924M4500
CoexpressionRODWELL_AGING_KIDNEY_DN

ENOSF1 NEBL FOLH1 ESRRG NAA35 SHANK2 CCNB1IP1 MMUT

8.45e-061481798M5408
CoexpressionRODWELL_AGING_KIDNEY_NO_BLOOD_DN

ENOSF1 NEBL FOLH1 ESRRG NAA35 SHANK2 CCNB1IP1 MMUT

8.45e-061481798M11837
CoexpressionGSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_UP

PDGFRA EPB41L4B ZRSR2 ITGA4 SGO1 PAPSS2 OR13J1 SERPINA10 CCNB1IP1

1.02e-052001799M9624
CoexpressionBENPORATH_NANOG_TARGETS

VAPB NEBL EXPH5 APOB SPAG9 SNUPN ARHGAP11A PAPSS2 IFI16 TTF1 GRHL2 ZEB2 NSD3 CEPT1 AP2A1 UBP1 GNA13 USP7 MICA EIF3F

1.50e-0598817920M6616
CoexpressionGSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN

NEBL HMGCR PBRM1 CLTC MPHOSPH9 CDC25A CDC27 ARAP2

1.86e-051651798M8121
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN

ZEB2 PIK3C2A ZFHX3 EIF3A MPHOSPH9 ARAP2

2.44e-05841796M13008
CoexpressionKRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP

ZRSR2 GBP3 DNAJB9 ZEB2 KRCC1 ESF1 NSD3 PTK2B GTF2H1 ASNS VPS35L USP7 CSTA PDCD11 UTP20 CCNB1IP1 ARAP2 FILIP1L B4GALT4

2.60e-0594217919M8144
CoexpressionMURARO_PANCREAS_BETA_CELL

VAPB CERK DMXL2 NEBL MAP1A EXPH5 ARFGEF2 LARP1 DNAJB9 CHN1 PAPSS2 EFR3A NCOR2 PIK3C2A GNA13 SYNE2 CLTC FMN2 ELP4

2.76e-0594617919M39169
CoexpressionGSE6259_CD4_TCELL_VS_CD8_TCELL_DN

CERK IFI16 SIRT1 PTK2B FRMD4A CRYBG1 TMEM131 EP300

4.07e-051841798M6739
CoexpressionGSE43955_1H_VS_42H_ACT_CD4_TCELL_DN

PDGFRA EPB41L4B SGO1 OR13J1 PHAF1 FAM111A NRK CRYBG1

7.32e-052001798M9665
CoexpressionGSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN

EXOC6 ERCC4 RBM10 PTK2B CEPT1 AP1B1 SYNE2 KDM1B

7.32e-052001798M6372
CoexpressionLINDGREN_BLADDER_CANCER_CLUSTER_2B

TPST1 CERK TRAF1 MAP1A PDGFRA ANXA6 ITGA4 DNAJB9 LIG4 DNAJB5 FILIP1L

8.01e-0538917911M4995
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

CERK TRAF1 EP400 RASA2 ANXA6 UBR4 GBP3 ITGA4 METTL23 SMC5 ZNF831 IFI16 ZEB2 EFR3A PTK2B FAM111A PHF3 UBTF GNA13 PIP4K2A CRYBG1 EIF3F EP300 ARAP2

8.41e-05149217924M40023
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#1_top-relative-expression-ranked_1000

PDGFRA ANXA6 HMGXB4 ITGA4 ZEB2 ITGB8 ESF1 UBTF GNA13 EIF3A

1.94e-0713617510gudmap_developingGonad_P2_epididymis_1000_k1
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#3_top-relative-expression-ranked_1000

PDGFRA ANXA6 HMGXB4 ITGA4 ZEB2 ITGB8 UBTF GNA13 NRK

8.40e-071231759gudmap_developingGonad_e16.5_epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_500

ANXA6 HMGXB4 ITGA4 ZEB2 ITGB8 GNA13 NRK EIF3A

8.61e-07911758gudmap_developingGonad_e16.5_epididymis_500_k4
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#2_top-relative-expression-ranked_1000

PDGFRA ANXA6 HMGXB4 ITGA4 ZEB2 ITGB8 UBTF GNA13 NRK

2.34e-061391759gudmap_developingGonad_e18.5_epididymis_1000_k2
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_1000

ANXA6 HMGXB4 ITGA4 ZEB2 ITGB8 NAA35 UBTF GNA13 NRK EIF3A

3.11e-0618417510gudmap_developingGonad_e14.5_ epididymis_1000_k2
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_500

ANXA6 HMGXB4 ITGA4 ITGB8 UBTF EIF3A

4.79e-06531756gudmap_developingGonad_P2_epididymis_500_k4
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

VAPB MYH6 ANXA6 HMGXB4 ZEB2 ESF1 NSD3 PTK2B NAA35 ADHFE1 PBRM1 SLC12A2 UBTF GNA13 NRK SYNE2 USP7 EIF3A CCNB1IP1 CDC25A

1.16e-0580617520gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_500

ANXA6 HMGXB4 ITGA4 ITGB8 UBTF EIF3A

2.86e-05721756gudmap_developingGonad_e18.5_epididymis_500_k5
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

DMXL2 ANXA6 HMGXB4 DNAJB9 ZEB2 SIRT1 ESF1 NSD3 NAA35 PBRM1 SLC12A2 GNA13 NRK SYNE2 USP7 ZFHX3 EIF3A CCNB1IP1 CDC25A

3.78e-0580417519gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#1_top-relative-expression-ranked_1000

MYH6 HMGXB4 ZEB2 PTK2B NAA35 ADHFE1 UBTF GNA13 NRK EIF3A

6.41e-0526117510gudmap_developingGonad_e12.5_epididymis_k1_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CYP4F8 ARFGEF2 HMGCR SMC5 SGO1 CHN1 TTF1 SIRT1 ESF1 FRMD4A LIG4 NAA35 AUNIP SHANK2 PHF3 SYNE2 USP7 UTP20 ZFHX3 STIP1 EIF3A KDM1B HSF2 CDC27

1.06e-04125717524facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#5_top-relative-expression-ranked_500

ANXA6 HMGXB4 ITGA4 ZEB2 UBTF NRK

1.07e-04911756gudmap_developingGonad_e14.5_ epididymis_500_k5
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#5_top-relative-expression-ranked_1000

ERCC4 VWA8 HMGXB4 ZEB2 EFR3A SLC12A2 PIK3C2A USP7 TTLL10

1.12e-042261759gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k5
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000

VAPB ANXA6 HMGXB4 HMGCR ZEB2 ITGB8 ESF1 NSD3 NAA35 PBRM1 SLC12A2 GNA13 NRK SYNE2 USP7 ZFHX3 EIF3A CDC25A

1.43e-0481517518gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

TPST1 DMXL2 ZRSR2 ARFGEF2 IDE RALGAPA2 SIRT1 ESF1 NEK3 AUNIP PPP5C FAM50A ASNS USP32 KDM1B CCNB1IP1 HSF2 RIMS2

1.54e-0482017518gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ARFGEF2 SMC5 ESF1 SYNE2 FMN2 STIP1 EIF3A MPHOSPH9

1.98e-041921758Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100

PDGFRA ITGA4 ITGB8 NRK

2.38e-04371754gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

KANSL1L DMXL2 ZRSR2 ANXA6 HMGXB4 DNAJB9 NEB ITGB8 ESF1 NSD3 NAA35 SLC12A2 GNA13 SYNE2 EIF3A KDM1B CCNB1IP1

2.50e-0477817517gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000

ERCC4 PDGFRA ESRRG ARFGEF2 NSD3 EFR3A PIK3C2A PHF3 GNA13 NRK

2.75e-0431217510gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

VAPB ANXA6 HMGXB4 ITGA4 ZEB2 ITGB8 ESF1 NSD3 NAA35 SLC12A2 UBTF GNA13 NRK SYNE2 USP7 ZFHX3 EIF3A

3.49e-0480117517gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_500

HMGXB4 PTK2B NAA35 UBTF GNA13 EIF3A

3.68e-041141756gudmap_developingGonad_e12.5_epididymis_k3_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

ERCC4 PDGFRA VWA8 ESRRG ARFGEF2 ITGA4 IFI16 GRHL2 NSD3 EFR3A PIK3C2A PHF3 GNA13 NRK FMN2 PIP4K2B TTLL10

3.75e-0480617517gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASA2 APOB SMC5 KMT5B PHF3 UBTF SYNE2 FILIP1L

1.05e-06191178860c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASA2 APOB SMC5 KMT5B PHF3 UBTF SYNE2 FILIP1L

1.05e-061911788973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L NEBL ESRRB ESRRG GRHL2 NAALADL2 ITGB8 SHANK2

1.18e-06194178893c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L NEBL ESRRB ESRRG GRHL2 NAALADL2 ITGB8 SHANK2

1.23e-0619517886477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANXA6 ZNF227 NAA35 FAM111A PHF3 SYNE2 PIP4K2A STIP1

1.27e-061961788ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L NEBL ESRRG GRHL2 NAALADL2 SHANK2 SYNE2 RIMS2

1.32e-0619717887e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

UACA GBP3 RALGAPA2 IFI16 SLC12A2 PIK3C2A GNA13 SYNE2

1.48e-062001788edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SPAG9 ITGA4 IFI16 ZEB2 PHF3 SYNE2 EIF3A ARAP2

1.48e-06200178812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIN3 RASA2 ITGA4 PIP4K2A MPHOSPH9 ELP4 ARAP2

5.42e-0616917878caf7996796a2e2716e3855de855c903d6126bf2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ABCA12 FOLH1 MROH2A APOB NEB NRK

9.45e-0618417872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ABCA12 FOLH1 MROH2A APOB NEB NRK

9.45e-061841787ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ABCA12 FOLH1 MROH2A APOB NEB NRK

9.45e-0618417872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

RASA2 ITGA4 ZNF831 IFI16 SYNE2 PIP4K2A CRYBG1

1.05e-051871787f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RASA2 ZEB2 SYNE2 PIP4K2A CRYBG1 MPHOSPH9 ARAP2

1.12e-0518917872c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 NEBL ESRRG PAPSS2 GRHL2 NAALADL2 CRYBG1

1.20e-05191178796b78b4e819ea6052334bfcbc7abbf35897df885
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASA2 APOB KMT5B PHF3 UBTF SYNE2 FILIP1L

1.20e-05191178709db184cb90fe282a14474d7217068c58092c6f8
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LARP1 PKD1L3 PTK2B FRMD4A PIP4K2A USP7 EP300

1.29e-051931787be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RASA2 ITGA4 ZNF831 IFI16 SYNE2 PIP4K2A ARAP2

1.33e-0519417873d6f2d190dd50804afea299957cc44c2bb756134
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ENOSF1 KANSL1L NEBL ESRRG ITGB8 SHANK2 SYNE2

1.33e-0519417877002937e8903e037332a215d00fbc7c7843b33f2
ToppCellMacrophages-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ZRSR2 IFI16 ZEB2 ITGB8 CEPT1 CSTA FILIP1L

1.38e-051951787e48bf57e6da23fbb4637a02387155f825455c49f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL ESRRG GRHL2 NAALADL2 ITGB8 SHANK2 CRYBG1

1.42e-051961787c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 ZEB2 AP1B1 CLTC CSTA ZFHX3 EIF3A

1.42e-05196178728e9e191361966df3a9bd48450090577aa72a999
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L NEBL ESRRG GRHL2 NAALADL2 ITGB8 SHANK2

1.42e-0519617876ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L NEBL ESRRB ESRRG GRHL2 NAALADL2 SHANK2

1.42e-051961787eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

UACA ZRSR2 TTF1 ESF1 EIF3A RIMS2 SMG6

1.47e-0519717870fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

TRAF1 GBP3 HMGCR RALGAPA2 SYNE2 EIF3A FILIP1L

1.62e-052001787a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FOLH1 ESRRG RALGAPA2 GRHL2 NAALADL2 SHANK2 SLC12A2

1.62e-0520017870eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DMXL2 RIN3 UBR4 PAPSS2 PTK2B GNA13 GPAT4

1.62e-052001787851c57187db8bc91a393655bca5f13e787a723d4
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Papillary_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

SPAM1 TGIF2LY DNAJB9 GNA13 USP32 CLTC

1.89e-0513717862a5d2a99a2c532480d00b80a4885514a8a5c80fa
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 ZNF831 PTK2B GCNT7 HP USP32

4.67e-051611786e227f7b711475624cf80e77f235b1783d88d57b4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 ZNF831 PTK2B GCNT7 HP USP32

4.67e-0516117868280a029026c272cae9649b27575831b0dd4e242
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG PAPSS2 NAALADL2 NRK RIMS2

4.84e-051621786373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA4 PTK2B SLC12A2 PIP4K2A USP32 FILIP1L

5.92e-051681786d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGA4 PTK2B SLC12A2 PIP4K2A USP32 FILIP1L

5.92e-051681786f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

HMGCR ITGA4 ARHGAP11A NCOR2 PDCD11 ADAM17

7.66e-0517617863de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ASIC2 ESRRG PAPSS2 GRHL2 SHANK2 CRYBG1

8.93e-051811786aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellLV-17._Lymphocyte|LV / Chamber and Cluster_Paper

RASA2 ITGA4 ZNF831 IFI16 PIP4K2A ARAP2

8.93e-05181178681fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG PAPSS2 NAALADL2 NRK RIMS2

9.21e-051821786a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 ESRRB ESRRG NAALADL2 SLC12A2 NRK

9.21e-0518217865f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

NEBL EXPH5 GRHL2 SHANK2 RHOBTB2 ARAP2

9.49e-0518317867b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCelldroplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP3 PAPSS2 ZEB2 THYN1 PDCD11 B4GALT4

9.49e-05183178692ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCelldroplet-Marrow-nan-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBP3 PAPSS2 ZEB2 THYN1 PDCD11 B4GALT4

9.49e-05183178624db9cc717e651586317c6a8e03a3401651273c1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 ESRRB ESRRG GRHL2 SLC12A2 NRK

9.49e-0518317862e831a4d99c6f983793df71c0994124c943c6da9
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA4 ZEB2 PHF3 EIF3A EP300 FILIP1L

9.78e-0518417861154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA4 CHN1 FRMD4A SLC12A2 ZFHX3 FILIP1L

9.78e-051841786327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 NEBL ESRRG NRK SYNE2 RIMS2

1.04e-041861786f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 NEBL ESRRG NRK SYNE2 RIMS2

1.07e-041871786c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYH6 CLTCL1 MYOM1 NEBL ESRRG NEB

1.10e-0418817866d249fe92d51a19da19ec14bb2262d394255d577
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DMXL2 ZEB2 FRMD4A FCHSD2 AP1B1 GNA13

1.10e-0418817863be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

TRAF1 ZEB2 SYNE2 TMEM131 ARAP2 SMG6

1.10e-041881786ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellhuman_hepatoblastoma-NK.T_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ITGA4 ZNF831 IFI16 PIP4K2A CRYBG1 ARAP2

1.10e-04188178671b7599e7e1d63cc0c8518c0501533755951d58f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG PAPSS2 GRHL2 NAALADL2 NRK

1.10e-0418817862ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 NEBL ESRRG SHANK2 SYNE2 RIMS2

1.10e-041881786af740fa78542438fdff627ea1f74f4eee43316be
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TRAF1 RIN3 RASA2 ITGA4 ZNF831 PIP4K2A

1.10e-0418817866686dbba990066568aa7573e70a7db8b4758f457
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 NEBL ESRRG GRHL2 NAALADL2 CRYBG1

1.10e-0418817864154f4787483c7e076e87a187733a9f666742c3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 NEBL ESRRG GRHL2 NAALADL2 CRYBG1

1.13e-04189178690aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 ESRRB ESRRG GRHL2 NAALADL2 NRK

1.13e-041891786975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellASK440-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

TRAF1 ANXA6 ITGA4 MEI1 ZNF831 SYNE2

1.13e-041891786868a387d19eb02bf41933e786b7d23e920a5d433
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EXOC6 EPB41L4B ASIC2 CHN1 PTK2B ARAP2

1.13e-041891786a75226616340045b581d08429d2e123e041dee55
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EXPH5 ESRRB ESRRG GRHL2 NAALADL2 NRK

1.13e-0418917867eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L NEBL ESRRB ESRRG GRHL2 NAALADL2

1.13e-041891786830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

RASA2 ITGA4 ZNF831 SYNE2 PIP4K2A ARAP2

1.13e-041891786b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 ASIC2 ESRRB ESRRG GRHL2 NRK

1.17e-041901786bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RASA2 ANXA6 ITGA4 ZEB2 SYNE2 ARAP2

1.17e-041901786d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 ASIC2 ESRRB ESRRG GRHL2 NRK

1.17e-041901786b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell(2)_Fibroblasts-(21)_Fibro-2|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

TRAF1 EPB41L4B ZEB2 ITGB8 FAM111A FILIP1L

1.17e-041901786d2afa08ad868acc6fce308ec21b0bf93591d4010
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EXPH5 ATP10B ARHGAP11A SGO1 GRHL2 SHANK2

1.20e-04191178639220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 ASIC2 ESRRB ESRRG GRHL2 NRK

1.20e-0419117862fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 NEBL ASIC2 ESRRB ESRRG RIMS2

1.20e-0419117869032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TPST1 NEBL ASIC2 ESRRB ESRRG RIMS2

1.20e-0419117865717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellCOVID-19-T_cells|COVID-19 / group, cell type (main and fine annotations)

RASA2 ITGA4 ZNF831 SYNE2 PIP4K2A ARAP2

1.20e-0419117867f64add931b64b8d35836fa6bee9ebab593844d3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ANXA6 ITGA4 IFI16 ZEB2 SYNE2 ARAP2

1.23e-041921786fdc741e1846cfd8ed741b160e3c611c310c5d36d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL ESRRB ESRRG NEB NRK SYNE2

1.23e-041921786ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A UBR4 PIP4K2A ZFHX3 EIF3A ARAP2

1.23e-0419217861ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

EFR3A PBRM1 PIK3C2A USP32 CLTC KDM1B

1.27e-041931786abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L TPST1 ASIC2 ESRRG ITGB8 SYNE2

1.27e-041931786f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ENOSF1 KANSL1L NEBL ESRRG NAALADL2 SHANK2

1.27e-0419317863866667dd221612589ae50f5c52f73a183a49ce6
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANSL1L CERK NEBL LIG4 KMT5B PIP4K2A

1.27e-041931786a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L TPST1 ASIC2 ESRRG ITGB8 SYNE2

1.27e-04193178642df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERK ZEB2 LIG4 FMN2 KDM1B CCNB1IP1

1.31e-04194178611709704079f24a730476572dc2f01e9d2226e2c
ToppCellILEUM-non-inflamed-(6)_ILC1|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RIN3 RASA2 IFI16 ZEB2 PIP4K2A B4GALT4

1.31e-041941786396f9a6b370721d425cbe335dbeea5f9514c92dc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L TPST1 ASIC2 GRHL2 ITGB8 SYNE2

1.31e-041941786e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERK ZEB2 LIG4 FMN2 KDM1B CCNB1IP1

1.31e-0419417863a1f95639d5f239f001bd67d4213e8938e7f299d
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

DMXL2 RIN3 PAPSS2 ZEB2 PTK2B ARAP2

1.31e-041941786c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L NEBL ESRRG GRHL2 ITGB8 SHANK2

1.31e-0419417865eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANSL1L CERK LIG4 KMT5B PHF3 PIP4K2A

1.31e-04194178666c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellhuman_hepatoblastoma-NK.T_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ITGA4 ZNF831 IFI16 PIP4K2A CRYBG1 ARAP2

1.31e-041941786997b02a22d7c89a8fd5615bb79a2a8a34fc3fee6
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

DMXL2 RIN3 PAPSS2 ZEB2 PTK2B FRMD4A

1.31e-041941786ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

MAP1A EXPH5 ESRRG APOB GRHL2

1.31e-0412217852aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EXOC6 RIN3 UACA IFI16 SHANK3 FCHSD2

1.34e-0419517866bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellP07-Mesenchymal|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TPST1 PDGFRA ANXA6 CHN1 ZEB2 FILIP1L

1.34e-041951786859764b605866b6c3e6edd0698670ca9c0f20745
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RASA2 ITGA4 ZEB2 PIP4K2A CRYBG1 ARAP2

1.34e-0419517860a72b8446399807ace5b6c72f865bb40dbd9e92d
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

DMXL2 RIN3 PAPSS2 ZEB2 PTK2B ARAP2

1.34e-0419517865e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellILEUM-non-inflamed-(6)_ILC-(6)_ILC1|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ITGA4 IFI16 ZEB2 PIP4K2A CRYBG1 ARAP2

1.38e-0419617868a3a63129adfbe58558af91336f81d397c291ed0
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZRSR2 ZEB2 CEPT1 CSTA ADAM17 FILIP1L

1.38e-041961786a7291291931f9e5abd6a54349bc920a0ab68a4cb
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 SPAG9 ZEB2 SIRT1 GNA13 EP300

1.38e-041961786c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DMXL2 SPAG9 ZEB2 SIRT1 GNA13 EP300

1.38e-04196178664c2abc0087bf2ae547932377f3662e3be1cc63e
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

NEBL EPB41L4B ESRRG GRHL2 SHANK2 CFAP44

1.38e-04196178687d9881cfec461a5d89b688a83749b618c519485
ToppCellmLN-B_cell-B_cell_cycling|B_cell / Region, Cell class and subclass

NEB ARHGAP11A ZNF831 NAA35 AUNIP SHANK2

1.42e-0419717862071526fe46de8359ea118ff78581eb4454aa55a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIN3 ITGA4 ZNF831 ZEB2 FCHSD2 GNA13

1.42e-041971786c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
DrugAC1L22FJ

FOLH1 ESRRB ESRRG HMGCR IDE NCOR2 ADHFE1 PBRM1 PIP4K2B MPHOSPH9 EP300

1.04e-0621317911CID000013766
DrugAcetohexamide [968-81-0]; Down 200; 12.4uM; HL60; HT_HG-U133A

KANSL1L TRAF1 CLTCL1 PTK2B GLYR1 ADAM17 EIF3A CFAP44 EP300 MMUT

3.80e-06197179101870_DN
DrugCephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; HL60; HT_HG-U133A

CERK EP400 EXPH5 LARP1 HMGCR SMC5 USP7 PIP4K2B CDC25A

8.76e-0617117992429_DN
DrugAC1Q6PMK

IMPA1 HMGCR ADHFE1 NRK ASNS

1.69e-05411795CID000000775
DrugProchlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A

ERCC4 SPAG9 ZNF227 NEK3 PPP5C GNA13 STIP1 ADAM17 HSF2

1.72e-0518617995010_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HG-U133A

ENOSF1 LARP1 ITGA4 ZEB2 UBTF GLYR1 UTP20 MPHOSPH9 EP300

1.87e-0518817991421_DN
DrugBenzbromarone [3562-84-3]; Up 200; 9.4uM; HL60; HT_HG-U133A

KANSL1L ZNF510 ITGA4 NEK3 UBTF GNA13 STIP1 ADAM17 HSF2

1.95e-0518917991291_UP
DrugCarteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A

UNC45A NEK3 PPP5C GNA13 GLYR1 PIP4K2B STIP1 DNAJB5 RIMS2

2.40e-0519417994176_DN
DrugNa 7

CLTCL1 GLYR1 CLTC

2.60e-0581793CID000446006
DrugLiothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A

RIN3 ERCC4 NEBL ZNF510 LIG4 NEK3 ADAM17 DNAJB5 SMG6

2.60e-0519617996602_DN
Drugnocodazole

TPST1 MYH6 CLTCL1 MAP1A ARFGEF2 SGO1 PTK2B NEK3 PPP5C NRK CLTC EIF3A CDC25A CDC27

2.63e-0547717914CID000004122
DrugZalcitabine [7481-89-2]; Down 200; 19uM; MCF7; HT_HG-U133A

VAPB SPAM1 ZNF227 PHF3 USP7 CSTA PIP4K2B ZNF839 RIMS2

2.71e-0519717997352_DN
DrugDiphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; HL60; HG-U133A

ENOSF1 CLTCL1 ITGA4 SMC5 NAA35 PPP5C STIP1 EIF3A CDC27

2.93e-0519917991994_UP
DrugMethiothepin maleate [19728-88-2]; Down 200; 8.4uM; PC3; HT_HG-U133A

VAPB MAP1A RASA2 ARFGEF2 NEB PAPSS2 NSD3 USP7 PIP4K2B

2.93e-0519917996312_DN
Drugcelecoxib; Down 200; 10uM; MCF7; HG-U133A

TPST1 ERCC4 MINPP1 GRHL2 KRCC1 FCHSD2 PPP5C PIP4K2B RIMS2

3.05e-052001799377_DN
Diseasemelanoma

ERCC4 RASA2 PDGFRA UBR4 ZNF831 PTK2B PIP4K2A CRYBG1 STIP1 EP300

2.49e-0624817510C0025202
DiseaseParoxysmal atrial fibrillation

MYH6 NEBL SIRT1 SYNE2 ZFHX3 KDM1B HSF2

4.24e-051561757C0235480
Diseasefamilial atrial fibrillation

MYH6 NEBL SIRT1 SYNE2 ZFHX3 KDM1B HSF2

4.24e-051561757C3468561
DiseasePersistent atrial fibrillation

MYH6 NEBL SIRT1 SYNE2 ZFHX3 KDM1B HSF2

4.24e-051561757C2585653
DiseaseAtrial Fibrillation

MYH6 NEBL SIRT1 SYNE2 ZFHX3 KDM1B HSF2

4.98e-051601757C0004238
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

ANKRD31 ABCA12 APOB HMGCR ZFHX3

5.73e-05691755EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Diseasepulse pressure measurement

FUT10 MYH6 TRAF1 RIN3 NEBL PDGFRA FOLH1 LEKR1 MEI1 PKD1L3 ZNF831 FAM186B NSD3 PBRM1 SLC12A2 PIK3C2A PIP4K2A ZFHX3 CDC25A FILIP1L SMG6

8.36e-05139217521EFO_0005763
Diseasecalcium measurement

ANKRD31 MAP1A ASIC2 LEKR1 ESRRG HMGCR METAP1 SLC12A2 UBTF SYNE2 CSTA ZFHX3 TMEM131

1.03e-0462817513EFO_0004838
Diseasehaptoglobin measurement

PKD1L3 HP ZFHX3

2.52e-04211753EFO_0004640
Diseaseatrial fibrillation

MYH6 NEBL MEI1 SIRT1 NCOR2 SYNE2 ZFHX3 KDM1B CDC27

3.94e-043711759EFO_0000275
Diseasehypertension (biomarker_via_orthology)

CYP4F8 PDGFRA PTK2B SLC12A2 HP CYP4F11 EP300

4.31e-042271757DOID:10763 (biomarker_via_orthology)
Diseasefree cholesterol in very large VLDL measurement

ANKRD31 EXOC6 APOB HMGCR

4.79e-04611754EFO_0022274
Diseasereading and spelling ability

SPAM1 ARFGEF2 NEB NAALADL2 FRMD4A FMN2

4.84e-041661756EFO_0005301
Diseasecholesterol to total lipids in small LDL percentage

ANKRD31 APOB HMGCR

5.40e-04271753EFO_0022241
Diseasecholesterol to total lipids in medium LDL percentage

ANKRD31 APOB HMGCR

5.40e-04271753EFO_0022238
Diseasereticulocyte measurement

RASA2 C6orf89 VWA8 ARFGEF2 LARP1 ITGA4 SGO1 ZEB2 SLC12A2 AP1B1 GNA13 SYNE2 USP32 TMEM131 MICA SMG6

5.63e-04105317516EFO_0010700
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

HMGCR IDE SIRT1 HP

6.10e-04651754DOID:0080208 (biomarker_via_orthology)
Diseasebreast carcinoma (is_marker_for)

PDGFRA ZFHX3 CDC25A EP300

6.47e-04661754DOID:3459 (is_marker_for)
DiseaseLDL cholesterol change measurement

APOB PKD1L3

7.20e-0471752EFO_0007804
Diseaseglycosyl ceramide (d18:1/20:0, d16:1/22:0) measurement

GBA2 SYNE2

7.20e-0471752EFO_0800551
Diseaseatrioventricular septal defect (implicated_via_orthology)

IFT172 GLYR1

7.20e-0471752DOID:0050651 (implicated_via_orthology)
Diseasefree cholesterol in large VLDL measurement

ANKRD31 EXOC6 APOB HMGCR

7.24e-04681754EFO_0022265
Diseasememory impairment

FUT10 SHANK3

9.57e-0481752EFO_0001072
Diseasemyocardial infarction

ANKRD31 C6orf89 APOB HMGCR PKD1L3 ZNF831 ZEB2 SMG6

1.21e-033501758EFO_0000612
DiseaseBurkitt Lymphoma

PDGFRA GNA13 PIP4K2A

1.27e-03361753C0006413
DiseaseCardiovascular Diseases

APOB SLC12A2 HP

1.27e-03361753C0007222
Diseasecolorectal health

VWA8 EXPH5 ESRRG LIG4 GLYR1 ZFHX3

1.31e-032011756EFO_0008460
Diseasefish oil supplement exposure measurement, triglyceride measurement

MAP1A METAP1

1.53e-03101752EFO_0004530, EFO_0600007
Diseasecardiovascular system disease (is_marker_for)

APOB HP

1.53e-03101752DOID:1287 (is_marker_for)
Diseasenephritis (implicated_via_orthology)

ITGA4 PTK2B

1.53e-03101752DOID:10952 (implicated_via_orthology)
Diseasetriglycerides to total lipids in large VLDL percentage

ANKRD31 APOB HMGCR

1.60e-03391753EFO_0022332
Diseaseplatelet crit

ANKRD31 RIN3 MAP1A C6orf89 EXPH5 LEKR1 APOB HMGCR METAP1 USP7 FMN2 EIF3A MPHOSPH9 SMG6

1.69e-0395217514EFO_0007985
Diseasefree cholesterol in medium LDL measurement

ANKRD31 APOB HMGCR

1.72e-03401753EFO_0022268
Diseaseliver fibrosis measurement

ANKRD31 C6orf89 APOB HMGCR

1.74e-03861754EFO_0010576
Diseasebeta thalassemia (is_marker_for)

APOB HP

1.86e-03111752DOID:12241 (is_marker_for)
DiseaseAutoimmune Diseases

HMGCR SIRT1 HP

1.99e-03421753C0004364
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

ANKRD31 APOB HMGCR SYNE2 MICA

2.05e-031501755EFO_0004611, EFO_0020947
Diseasesleep duration, low density lipoprotein cholesterol measurement

ANKRD31 APOB HMGCR PKD1L3

2.14e-03911754EFO_0004611, EFO_0005271
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

ANKRD31 EXOC6 APOB HMGCR FCHSD2

2.24e-031531755EFO_0004611, EFO_0020944
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

EXOC6 MAP1A APOB HMGCR METAP1 NCOR2

2.26e-032241756EFO_0004574, EFO_0008317
Diseasecholesterol to total lipids in large VLDL percentage

ANKRD31 APOB HMGCR

2.42e-03451753EFO_0022236
Diseasemiddle cerebral artery infarction (implicated_via_orthology)

PDGFRA SIRT1 SLC12A2

2.42e-03451753DOID:3525 (implicated_via_orthology)
Diseaseosteoarthritis, knee

SNUPN FRMD4A MPHOSPH9 EP300 SMG6

2.57e-031581755EFO_0004616
Diseasemyeloid leukemia (is_implicated_in)

PDGFRA NSD3

2.61e-03131752DOID:8692 (is_implicated_in)
DiseaseHyperlipoproteinemia Type IIb

APOB HMGCR

2.61e-03131752C1704417
DiseaseGastrointestinal Stromal Sarcoma

PDGFRA IFT172 ELP4

2.75e-03471753C3179349
Diseasecholesteryl esters to total lipids in small VLDL percentage

ANKRD31 APOB HMGCR

3.09e-03491753EFO_0022256
Diseasebreast carcinoma

RIN3 NEBL RASA2 LEKR1 ESRRG SNUPN GRHL2 FRMD4A SLC12A2 KMT5B PIP4K2A HSF2 FILIP1L SMG6

3.13e-03101917514EFO_0000305
DiseaseGastrointestinal Stromal Tumors

PDGFRA IFT172 ELP4

3.28e-03501753C0238198
Diseasefree cholesterol in LDL measurement

ANKRD31 APOB HMGCR

3.28e-03501753EFO_0022266
Diseasefree cholesterol in large LDL measurement

ANKRD31 APOB HMGCR

3.47e-03511753EFO_0022176
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

ANKRD31 APOB HMGCR

3.47e-03511753EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Diseaseinfant head circumference

LEKR1 ARFGEF2

3.49e-03151752EFO_0004577
Diseaseupper aerodigestive tract neoplasm

C6orf89 SMC5 HELQ METAP1 GTF2H1 ZFHX3

3.59e-032461756EFO_0004284
Diseasephospholipids in IDL measurement

ANKRD31 APOB HMGCR

3.66e-03521753EFO_0022164
Diseasehair colour measurement

TRAF1 RIN3 RASA2 ASIC2 FOLH1 MROH2A PKD1L3 ZNF831 SYNE2 FMN2

3.83e-0361517510EFO_0007822
Diseasecongestive heart failure (biomarker_via_orthology)

MYH6 RBM10 HP ADAM17

3.84e-031071754DOID:6000 (biomarker_via_orthology)
Diseasephospholipids in large LDL measurement

ANKRD31 APOB HMGCR

3.86e-03531753EFO_0022174
Diseasetriglycerides to total lipids in very large VLDL percentage

ANKRD31 APOB HMGCR

3.86e-03531753EFO_0022340
DiseaseProstatic Neoplasms

TRAF1 FOLH1 SIRT1 SLC12A2 THYN1 USP7 ZFHX3 EIF3A CDC27 B4GALT4

3.88e-0361617510C0033578
DiseaseMalignant neoplasm of prostate

TRAF1 FOLH1 SIRT1 SLC12A2 THYN1 USP7 ZFHX3 EIF3A CDC27 B4GALT4

3.88e-0361617510C0376358
DiseaseHyperlipoproteinemia Type IIa

APOB HMGCR

3.97e-03161752C0745103
Diseasebehavioural inhibitory control measurement

MROH2A EFR3A

3.97e-03161752EFO_0008467
Diseasediabetic retinopathy (implicated_via_orthology)

ITGA4 EP300

3.97e-03161752DOID:8947 (implicated_via_orthology)
DiseaseDiffuse Large B-Cell Lymphoma

GNA13 CLTC EP300

4.29e-03551753C0079744
Diseasepathological myopia

ANXA6 ZEB2 AP1B1 ASNS

4.37e-031111754EFO_0004207
Diseaseschizophrenia, irritable bowel syndrome

MPHOSPH9 EP300

4.49e-03171752EFO_0000555, MONDO_0005090
Diseasesphingomyelin 14:0 measurement

SYNE2 ZFHX3

4.49e-03171752EFO_0010390
Diseasecholesteryl esters to total lipids in large VLDL percentage

ANKRD31 APOB HMGCR

4.51e-03561753EFO_0022250
Diseasepancreatic cancer (is_implicated_in)

ERCC4 PDGFRA ITGA4 LIG4

4.52e-031121754DOID:1793 (is_implicated_in)
Diseasetotal lipids in large LDL

ANKRD31 APOB HMGCR

4.74e-03571753EFO_0022163
Diseasecholesterol in large LDL measurement

ANKRD31 APOB HMGCR

4.74e-03571753EFO_0021901
DiseaseMalignant neoplasm of breast

UBR4 ARFGEF2 ARHGAP11A HELQ ZEB2 SIRT1 ADHFE1 PBRM1 HP CHD5 SYNE2 UTP20 CDC27 EP300

4.96e-03107417514C0006142
Diseasecholesterol in IDL measurement

ANKRD31 APOB HMGCR

4.98e-03581753EFO_0021899
Diseasesweet liking measurement

ATP10B PNLIPRP3

5.03e-03181752EFO_0010156
DiseaseTourette syndrome, schizophrenia

NSD3 PHF3

5.03e-03181752EFO_0004895, MONDO_0005090
DiseaseHypercholesterolemia, Familial

APOB HMGCR

5.03e-03181752C0020445
Diseasecoronary artery disease

ANKRD31 EXOC6 CLTCL1 ASIC2 ARFGEF2 APOB HMGCR PKD1L3 SPATA2 ZNF831 ZEB2 FMN2 PIP4K2B CDC25A SMG6

5.14e-03119417515EFO_0001645
Diseasephospholipids in VLDL measurement

EXOC6 APOB HMGCR

5.23e-03591753EFO_0022301
Diseasefree cholesterol to total lipids in very large VLDL percentage

ANKRD31 APOB HMGCR

5.23e-03591753EFO_0022289
Diseasetotal lipids in IDL

ANKRD31 APOB HMGCR

5.48e-03601753EFO_0022161
Diseasetotal lipids in VLDL measurement

EXOC6 APOB HMGCR

5.48e-03601753EFO_0022314
Diseaseglycoprotein measurement

EXOC6 APOB PKD1L3 ZFHX3

5.59e-031191754EFO_0004555
Diseaseemphysema pattern measurement

RIN3 VWA8

5.60e-03191752EFO_0005850
Diseaseglomerulonephritis (is_marker_for)

PTK2B EP300

5.60e-03191752DOID:2921 (is_marker_for)
Diseasecomplex trait

ANKRD31 DMXL2 RASA2 IFT172 APOB HMGCR

5.72e-032711756EFO_0010578
Diseasefree cholesterol in IDL measurement

ANKRD31 APOB HMGCR

5.74e-03611753EFO_0022181
Diseasefree cholesterol in VLDL measurement

EXOC6 APOB HMGCR

5.74e-03611753EFO_0022276

Protein segments in the cluster

PeptideGeneStartEntry
DLKANKTFAYHKDMP

TPST1

56

O60507
KKKSNHQEFEAVAMP

TTF1

336

Q15361
KPNGKVASVEMVKYH

ASNS

191

P08243
LHYCKDKAKDFMPAS

SMG6

1361

Q86US8
SQKLYATMEKHKEVF

EP300

1581

Q09472
MDFLAFKKKHYAPLQ

EP400

401

Q96L91
KMALKYHPDKNKEPN

DNAJB5

26

O75953
MLFLMKPNHAEYASK

CXorf65

51

A6NEN9
PFKSEVHKGNYLEMK

CHD5

1771

Q8TDI0
IPKAKEFMANFHKTL

B4GALT4

41

O60513
TKFMQLHFPKTYLKD

ABCA12

2501

Q86UK0
LKINDEKFKAHASMY

ARFGEF2

1721

Q9Y6D5
KIFKANHPMDAEVTK

AP2A1

891

O95782
MQDIPIYANVHKTKK

ARAP2

71

Q8WZ64
ILKHEMKVFFVKYND

AP1B1

316

Q10567
DFIIGYKPHKEDMEK

DMXL2

856

Q8TDJ6
QISPANIKKKVYHMD

FAM186B

651

Q8IYM0
FHKLAMKYHPDKNKS

DNAJB9

46

Q9UBS3
MKYHPDKNKSPDAEA

DNAJB9

51

Q9UBS3
NEKLPKHMQFKRTDF

CFAP44

966

Q96MT7
MLPKSLEKHEKDLYF

EFR3A

646

Q14156
EKPNNHLNKFKGYME

ATP10B

241

O94823
PAHYDAKQLKKAMEG

ANXA6

436

P08133
FIKMTNYDVEHTIKK

ANXA6

566

P08133
ANFKHYKPKQFSMLE

ASIC2

141

Q16515
KVSMHYSDPKPKINE

RBM10

201

P98175
KKNMFQVIHTEKPLY

RASA2

671

Q15283
VQPKAMKIEKSFDAH

SPAG9

1071

O60271
RNFLKEDAMKTKTHY

MICA

166

Q29983
DTVHQMKPYLKKSVS

ANKRD31

1646

Q8N7Z5
YNKIKSGYRMAKPDH

PDGFRA

906

P16234
EMVLKIIAFKPKHYF

CACNA1F

1236

O60840
EKETFREKFMQHPKN

NCOR2

436

Q9Y618
NKAKKAMDFYDPARH

PAPSS2

556

O95340
HFNKKMYEEFKQLAL

LARP1

926

Q6PKG0
ETEHEPTKMFYKKEV

PBRM1

1201

Q86U86
HHPKKQSDGMEEYKT

KANSL1L

961

A0AUZ9
MNRHFSKEDIYAAKK

nan

1076

O00370
LMKKFEYSPSKVHLI

PNLIPRP3

151

Q17RR3
VPHYAKNKAVGVMKS

METAP1

306

P53582
KAEGFYQKHMQEPLK

MAP1A

676

P78559
KFTDHLKYVMLPVAD

HP

291

P00738
YLILHEFKAMEEKVK

LEKR1

31

Q6ZMV7
PASMNYAKAHSKDKK

MEPE

181

Q9NQ76
KALSKLHEYFPEMQI

HMGCR

666

P04035
NKMQEKLFKEHVFIY

KMT5B

171

Q4FZB7
KYADKIYSISMKHPQ

FOLH1

606

Q04609
TEMKEESVKKHQYPD

ENOSF1

416

Q7L5Y1
MFHDKKFKLNYAVDK

ESF1

41

Q9H501
STAPKMIYDLFRKHK

OR4F6

76

Q8NGB9
NKHLYQIEKPCKEAM

PIK3C2A

531

O00443
KVEQLKPYHAHKEEM

GLYR1

56

Q49A26
NLYKSKDPKEFMEHI

MPHOSPH9

56

Q99550
KDTSKMYIPHTDKSN

EXPH5

776

Q8NEV8
DILATIYFLMHKNPK

METTL23

111

Q86XA0
YMKNSFKDVDHLFQK

GBP3

366

Q9H0R5
IHEYDFEIKNVPFKM

GNA13

206

Q14344
SHKSKKMKPLYVNTE

HMGXB4

166

Q9UGU5
IFMYLKPKSKEAHIS

OR13J1

256

Q8NGT2
DVMKDISKHYSQKAA

PPP1R21

436

Q6ZMI0
KNHMFFIAITKKPEV

RALGAPA2

1776

Q2PPJ7
EMKTKHKAYENAVGI

GOLGA3

991

Q08378
VYDDQPNAHKKFMEK

EXOC6

36

Q8TAG9
KMKHPNIVAFKESFE

NEK3

56

P51956
ALKHKTPEVHLKYAM

IFT172

1136

Q9UG01
NLFVIVPHMKEKFSK

MEI1

581

Q5TIA1
KEPQTKLHQQFEMYK

RIMS2

86

Q9UQ26
AEANFMLKVHPLKKY

ITGB8

131

P26012
YHRNDYDKSPIKPKM

FRMD4A

596

Q9P2Q2
DMLIKKLKSFDYHQF

APOB

2421

P04114
AMIYKKSAVQLFEKH

CEPT1

301

Q9Y6K0
KKSDITYFKTMPDLH

GRHL2

461

Q6ISB3
VFYDMDPQKKHSVLM

KDM1B

696

Q8NB78
KDMKHQSFYIETKLD

LIG4

261

P49917
HVDEKAPMKYKTAVQ

GCNT7

141

Q6ZNI0
YRKTHVEKKTPFIDM

GBA2

126

Q9HCG7
EFAKNMYELHKKVSP

EIF3F

151

O00303
PALDVLYDVMKSKKH

EIF3A

26

Q14152
MERGAKEKNHQLYKP

GPAT4

61

Q86UL3
YEKPMNELDKVVEKH

FILIP1L

136

Q4L180
QKMEKPYAFTVHCVK

CERK

76

Q8TCT0
KMEEAPTHLNSFLKK

FUT10

51

Q6P4F1
YNIKLEGKVPMHKLF

ESRRG

436

P62508
KCNMKIEHYFSPVSK

FAM111A

16

Q96PZ2
MKSNIDKKFSAHYDA

FAM50A

41

Q14320
HFNILKPYMKIFNKS

CYP4F11

156

Q9HBI6
KPYIKIFSKSANIMH

CYP4F8

161

P98187
DNKYMHLKVFKSLPG

CSTA

61

P01040
YEPKEQKKMFHATVA

IFI16

591

Q16666
KPHENKTYLAVGSMK

ITGA4

641

P13612
MKHSKKTYDSFQDEL

KRCC1

1

Q9NPI7
QDHLDKAKKDITFYM

SPAM1

121

P38567
EHMLFLGTKKYPKEN

IDE

111

P14735
LKSPSHMEKYPQKEK

CRYBG1

916

Q9Y4K1
HMEKYPQKEKTKEDL

CRYBG1

921

Q9Y4K1
VYNHKTPESNIKMKI

ELP4

146

Q96EB1
YSVKLQGKVPMHKLF

ESRRB

411

O95718
GKKKYFETEQMAHAV

FCHSD2

151

O94868
LEQKYMQLPEHKKHA

HELQ

126

Q8TDG4
FFKDMPHNALDKKSN

PTK2B

186

Q14289
AYKKHMPVLKETHDE

CHN1

156

P15882
IAKKYMSENKGVPLH

C6orf89

111

Q6UWU4
KVYQVSSKEHMQPFK

FMN2

1596

Q9NZ56
YKQEKFSLAEMHFQK

CDC27

646

P30260
IKKQMKIGPAYALHF

EPB41L4B

146

Q9H329
KQVEQYMSFHKLPAD

HCN2

481

Q9UL51
EFLKKYMHKVMNDLP

ISM1

306

B1AKI9
KKDMNETFREKFPHV

CABLES2

341

Q9BTV7
KNYQSMEKHTKLPGD

AUNIP

206

Q9H7T9
KENMPSHFKFKEYCP

PIP4K2A

81

P48426
YRPMHHEDFKEDLKK

CDC25A

486

P30304
KILQKFTSMHKAYSP

RIN3

741

Q8TB24
KEILPKYFKHNNMAS

HSF2

46

Q03933
KMYKAKDYNVDHPLV

ADHFE1

341

Q8IWW8
DMNSADPFHLKYIIK

MROH5

96

Q6ZUA9
MKQMSTHYLKKLDFP

MROH2A

1616

A6NES4
CKKPLIHMYEKEFTS

NRK

1196

Q7Z2Y5
YAMTPIFDEKMLKHE

UTP20

1616

O75691
KDIHSNMPKDYLSKQ

ARHGAP11A

701

Q6P4F7
KHRFKAYPSEEEKQM

TGIF2LX

71

Q8IUE1
KHRFKAYPSEEEKQM

TGIF2LY

71

Q8IUE0
KHYDKAKELDPTNMT

STIP1

246

P31948
PFDLHAMQNIILKYK

SYNE2

1291

Q8WXH0
YQPKFKTEKEFMQHA

MRPL45

46

Q9BRJ2
EKMLISSIKEKYPSH

IMPA1

51

P29218
KPHDKDAKMKYQECN

PPP5C

126

P53041
VDVYAMKSHESSPKK

PIP4K2B

346

P78356
KAMSPENQEYFEKHR

RHOBTB2

651

Q9BYZ6
VMPLKKHQDNKYPAD

PKD1L3

86

Q7Z443
PQKKMHKSVSSNDAY

SGO1

321

Q5FBB7
ENLPEQFHRAMKYDK

SIRT1

416

Q96EB6
MDIDTVKKLPKHYAN

SNUPN

86

O95149
DMTFKAKLYDNHLGK

MYH6

546

P13533
MLGSPHKVFYKSEDK

PHAF1

251

Q9BSU1
ETIDINKDPYFMKNH

SF3A2

36

Q15428
KMKPIIHKSNALYQD

SHANK2

1551

Q9UPX8
KHYNMAKSYPNEEKD

ADAM17

296

P78536
FSKAEGHLKQMEKIY

CCNB1IP1

111

Q9NPC3
AILYSKFKPQKMREH

CLTC

1321

Q00610
AILYSKFKPQKMLEH

CLTCL1

1321

P53675
PDHALVKKYMKLQHV

CNGA4

281

Q8IV77
ADILMKNPEKKYHIG

PDCD11

486

Q14690
KYAENVPHNMTEKEF

GTF2H1

206

P32780
PCYKKSELHKFMPNN

SPATA2

491

Q9UM82
EYIKKQSKQPDMTHL

VPS35L

936

Q7Z3J2
DKEPLTAYNYKKQMH

MINPP1

386

Q9UNW1
PVHYLQFKEMSDLNK

NAA35

631

Q5VZE5
LKKFMDYVQLHSTDK

SHANK3

116

Q9BYB0
LIKNKMKAFYAPVHA

SLC12A2

846

P55011
EAKTMFKVHNFSKPV

TMEM131

476

Q92545
YKAHVMSSLKQGKEP

ZNF840P

86

A6NDX5
NLKYHPGEENFKLTM

ZHX1

121

Q9UKY1
VKEEVCMSLKPEYHK

PHF3

181

Q92576
PKHAYVKDDTMFLKC

TRAF1

396

Q13077
KIKTEPKQMHEDYCF

NSD3

1311

Q9BZ95
FFPKFKLDQKYEMHE

SERPINA10

336

Q9UK55
IFHIYLKAKKMTTFE

ZDHHC11

256

Q9H8X9
YEFLLMKVEKDHLAK

ZNF839

381

A8K0R7
KNHYVPLKVSEDMKK

UACA

741

Q9BZF9
LMKIVKEAYPDHTQF

THYN1

126

Q9P016
MEKRTAHEKEKYQPS

UBP1

251

Q9NZI7
DFMKKSPFHEHIKTD

ZNF227

206

Q86WZ6
TGEKFYEHNKNMKAL

ZNF510

221

Q9Y2H8
FDYDPNEKSKHKFMV

VAPB

76

O95292
ARVYHLPDAKMSKKE

ERCC4

341

Q92889
RNNMEASVPKYKKHL

WHAMMP3

21

Q1A5X7
ETFKRIYQKMKASPH

ZNF831

626

Q5JPB2
IFHIYLKAKKMTTFE

ZDHHC11B

256

P0C7U3
EEISKLKGYHMKDPC

ZEB2

481

O60315
KRAKYAKLHPEMSNL

UBTF

126

P17480
KMKVPDVLFYDNIQH

VWA8

746

A3KMH1
MKDNKNAKYIENHIP

SMC5

491

Q8IY18
ALDYMKKHIPSAKNL

UBR4

4691

Q5T4S7
FMQKKSPLYMLLKEH

TTLL10

421

Q6ZVT0
KDHDVMLFLKMYDPK

USP7

681

Q93009
KMTFPEKPSHKKYRA

ZRSR2

6

Q15696
DPKMVELAKYAKQHV

UNC45A

606

Q9H3U1
YAQFLPKTDGKKMAD

USP32

1571

Q8NFA0
KYQQTLEAHMKEKHP

ZFHX3

681

Q15911
KKMAYQKVHADQRAP

NAALADL2

16

Q58DX5
IIADIFEYTAKHMPK

MMUT

241

P22033
EKEIFEGPKYKMHID

MYOM1

1281

P52179
DNEMKDKKHHYNPLE

NEBL

236

O76041
NVKYKKDIQNMHDPV

NEBL

266

O76041
EKTKSKYNTPHDMFN

NEB

1131

P20929
DYHKTKAKINIPADM

NEB

4291

P20929