Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein kinase activity	NRBP1 NEK6 GRK4 LRRK2 SRPK2 BCR MELK PIK3R4 CDKL5 STRADB COQ8A PIK3C3 IRAK4 ATM CDK11B TAF1L	4.55e-05	600	167	16	GO:0004672
GeneOntologyMolecularFunction	calcium ion binding	EFCAB5 SPARC REPS1 ACTN4 CUBN MELK RYR2 EYS FAT1 SLC25A12 CELSR2 HMCN1 TLL1 SLIT1 ITSN2 MACF1 PLSCR2 PLS1	5.82e-05	749	167	18	GO:0005509
GeneOntologyMolecularFunction	UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity	GXYLT1 GXYLT2	6.95e-05	2	167	2	GO:0140563
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	NRBP1 NEK6 GRK4 LRRK2 SRPK2 BCR MELK PIK3R4 CDKL5 IRAK4 ATM CDK11B TAF1L	1.00e-04	446	167	13	GO:0004674
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	NRBP1 NEK6 GRK4 LRRK2 SRPK2 BCR MELK PIK3R4 CDKL5 STRADB COQ8A PIK3C3 IRAK4 ATM CDK11B TAF1L	3.09e-04	709	167	16	GO:0016773
GeneOntologyMolecularFunction	5'-3' RNA exonuclease activity	DCP2 XRN1	4.13e-04	4	167	2	GO:0004534
Domain	Growth_fac_rcpt_	FRAS1 HTRA1 CUBN EYS FAT1 CELSR2 HMCN1 SLIT1 TNXB	1.14e-05	156	167	9	IPR009030
Domain	EGF	CUBN EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1 TNXB	1.77e-05	126	167	8	PF00008
Domain	LAM_G_DOMAIN	COL24A1 EYS FAT1 CELSR2 SLIT1	2.13e-05	38	167	5	PS50025
Domain	Laminin_G_2	COL24A1 EYS FAT1 CELSR2 SLIT1	2.75e-05	40	167	5	PF02210
Domain	EGF-type_Asp/Asn_hydroxyl_site	CUBN EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1	4.67e-05	106	167	7	IPR000152
Domain	EGF	FRAS1 CUBN ADAM28 EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1 TNXB	5.18e-05	235	167	10	SM00181
Domain	DVL-1	DVL1P1 DVL1	7.95e-05	2	167	2	IPR008340
Domain	Glyco_transf_8	GLT8D2 GXYLT1 GXYLT2	8.05e-05	10	167	3	PF01501
Domain	Glyco_trans_8	GLT8D2 GXYLT1 GXYLT2	8.05e-05	10	167	3	IPR002495
Domain	EGF-like_dom	FRAS1 CUBN ADAM28 EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1 TNXB	8.39e-05	249	167	10	IPR000742
Domain	EGF_1	CUBN ITGB4 ADAM28 EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1 TNXB	1.02e-04	255	167	10	PS00022
Domain	Kinase-like_dom	NRBP1 NEK6 GRK4 LRRK2 SRPK2 MELK PIK3R4 CDKL5 STRADB COQ8A PIK3C3 IRAK4 MACF1 ATM CDK11B	1.10e-04	542	167	15	IPR011009
Domain	EGF_CA	CUBN EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1	1.14e-04	122	167	7	SM00179
Domain	EGF-like_CS	CUBN ITGB4 ADAM28 EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1 TNXB	1.24e-04	261	167	10	IPR013032
Domain	EGF-like_Ca-bd_dom	CUBN EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1	1.26e-04	124	167	7	IPR001881
Domain	EGF_2	CUBN ITGB4 ADAM28 EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1 TNXB	1.40e-04	265	167	10	PS01186
Domain	ConA-like_dom	ITGB4 RYR2 LGALS4 SPRYD7 COL24A1 EYS FAT1 CELSR2 SLIT1	1.61e-04	219	167	9	IPR013320
Domain	Laminin_G	COL24A1 EYS FAT1 CELSR2 SLIT1	1.68e-04	58	167	5	IPR001791
Domain	EF_Hand_1_Ca_BS	EFCAB5 SPARC REPS1 ACTN4 SLC25A12 ITSN2 MACF1 PLS1	1.81e-04	175	167	8	IPR018247
Domain	-	LGALS4 COL24A1 EYS FAT1 CELSR2 SLIT1	2.10e-04	95	167	6	2.60.120.200
Domain	EGF_Ca-bd_CS	CUBN EYS FAT1 HMCN1 TLL1 SLIT1	2.36e-04	97	167	6	IPR018097
Domain	EF_HAND_2	EFCAB5 SPARC REPS1 ACTN4 RYR2 SLC25A12 ITSN2 MACF1 PLS1	2.39e-04	231	167	9	PS50222
Domain	EF_hand_dom	EFCAB5 SPARC REPS1 ACTN4 RYR2 SLC25A12 ITSN2 MACF1 PLS1	2.47e-04	232	167	9	IPR002048
Domain	EGF_CA	CUBN EYS FAT1 HMCN1 TLL1 SLIT1	2.63e-04	99	167	6	PS01187
Domain	EGF_3	CUBN ADAM28 EYS FAT1 CELSR2 HMCN1 TLL1 SLIT1 TNXB	2.71e-04	235	167	9	PS50026
Domain	EF-hand_1	REPS1 ACTN4 RYR2 SLC25A12 ITSN2 MACF1 PLS1	4.40e-04	152	167	7	PF00036
Domain	Dishevelled	DVL1P1 DVL1	4.71e-04	4	167	2	PF02377
Domain	Dishevelled_fam	DVL1P1 DVL1	4.71e-04	4	167	2	IPR008339
Domain	Dishevelled_protein_dom	DVL1P1 DVL1	4.71e-04	4	167	2	IPR003351
Domain	EF_HAND_1	EFCAB5 SPARC REPS1 ACTN4 SLC25A12 ITSN2 MACF1 PLS1	5.08e-04	204	167	8	PS00018
Domain	-	EFCAB5 SPARC REPS1 ACTN4 RYR2 SLC25A12 ITSN2 MACF1 PLS1	5.82e-04	261	167	9	1.10.238.10
Domain	PSI	PLXND1 ITGB4 SEMA3D SEMA6A	6.33e-04	44	167	4	IPR016201
Domain	LamG	EYS FAT1 CELSR2 SLIT1	6.33e-04	44	167	4	SM00282
Domain	Pkinase	NRBP1 NEK6 GRK4 LRRK2 SRPK2 MELK PIK3R4 CDKL5 STRADB IRAK4 CDK11B	6.51e-04	381	167	11	PF00069
Domain	PSI	PLXND1 ITGB4 SEMA3D SEMA6A	7.51e-04	46	167	4	SM00423
Domain	ACTININ_2	ACTN4 MACF1 PLS1	1.09e-03	23	167	3	PS00020
Domain	ACTININ_1	ACTN4 MACF1 PLS1	1.09e-03	23	167	3	PS00019
Domain	Actinin_actin-bd_CS	ACTN4 MACF1 PLS1	1.09e-03	23	167	3	IPR001589
Domain	EF-hand-dom_pair	EFCAB5 SPARC REPS1 ACTN4 RYR2 SLC25A12 ITSN2 MACF1 PLS1	1.14e-03	287	167	9	IPR011992
Domain	ADEAMc	ADAD1 ADAD2	1.16e-03	6	167	2	SM00552
Domain	A_deamin	ADAD1 ADAD2	1.16e-03	6	167	2	PF02137
Domain	A_DEAMIN_EDITASE	ADAD1 ADAD2	1.16e-03	6	167	2	PS50141
Domain	A_deamin	ADAD1 ADAD2	1.16e-03	6	167	2	IPR002466
Domain	PROTEIN_KINASE_ST	NEK6 GRK4 LRRK2 SRPK2 MELK PIK3R4 CDKL5 STRADB IRAK4 CDK11B	1.59e-03	362	167	10	PS00108
Domain	DIX	DVL1P1 DVL1	1.62e-03	7	167	2	PF00778
Domain	DIX	DVL1P1 DVL1	1.62e-03	7	167	2	IPR001158
Domain	DIX	DVL1P1 DVL1	1.62e-03	7	167	2	PS50841
Domain	DAX	DVL1P1 DVL1	1.62e-03	7	167	2	SM00021
Domain	PROTEIN_KINASE_DOM	NRBP1 NEK6 GRK4 LRRK2 SRPK2 MELK PIK3R4 CDKL5 STRADB COQ8A IRAK4 CDK11B	1.63e-03	493	167	12	PS50011
Domain	hEGF	EYS CELSR2 SLIT1	1.95e-03	28	167	3	PF12661
Domain	ASX_HYDROXYL	CUBN EYS FAT1 CELSR2 HMCN1	2.05e-03	100	167	5	PS00010
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	HTRA1 VWA8 SRPK2 BCR FOXP4 FAT1 ARID1B SLC25A12 PELO EIF4ENIF1 DNAJC10 BRCA1 COQ8A UBR5 ACTR6 NFRKB XRN1 EHMT1 ANKRD28 MACF1 PPIH SLC25A19 WDR62	6.49e-09	1116	170	23	31753913
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	BIRC6 UBR5 SLIT1 ZBTB40 WDR35 EHMT1 ANKRD28 MACF1 OGA ARAP1	1.81e-07	225	170	10	12168954
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	FRAS1 PLXND1 TLL1 SEMA6A ICA1L WDR62 DNAH11	6.43e-07	100	170	7	25807483
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	ACTN4 CLASP2 BCR PPP1CB EIF4ENIF1 UBR5 ANKRD28 MACF1 WDR62	9.83e-07	209	170	9	36779422
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	HTRA1 CYP2C18 NHLRC2 CUBN PPP1R3C FRA10AC1 PTPRE UPF2 SLIT1 DNAJC1 DNMBP ALOX5	1.07e-06	415	170	12	16385451
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	NRBP1 HYOU1 NEK6 PSMA3 SRPK2 CLASP2 COPS3 PRPF8 PPP1CB PIK3R4 SLC25A12 PELO UBR5 PIK3C3 CEP135 ADI1 CDK11B TAGLN RPA3 ATP2A3 UNC79	1.38e-06	1284	170	21	17353931
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	LRRK2 CLASP2 PLXND1 BIRC6 RYR2 MKS1 PCF11 CDKL5 FAT1 BRCA1 UBR5 XRN1 EHMT1 ANKRD28 COIL SLC25A19	1.53e-06	777	170	16	35844135
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	VWA8 PRPF8 THOC2 PPP1CB PCF11 NEFM ARID1B SLC25A12 DNAJC10 UPF2 IRAK4 EHMT1 MACF1 ATM CDK11B COIL PPIH SLC25A19 TNXB	1.64e-06	1082	170	19	38697112
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 REPS1 VWA8 DVL1 RAPGEF1 CLASP2 PLXND1 BCR BIRC6 ITGB4 FAT1 EIF4ENIF1 CELSR2 EHMT1 TAGLN DNMBP ATP2A3 ALOX5 ARAP1	2.22e-06	1105	170	19	35748872
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	EFCAB5 HYOU1 ANKS1B ACTN4 ZDHHC17 PRPF8 RYR2 PPP1CB PCF11 NEFM FRA10AC1 SLC25A12 CLCN3 DNAJC10 BRCA1 ITSN2 XRN1 PDIA2 MACF1 ATM ATP2A3 PLS1	2.36e-06	1442	170	22	35575683
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	HYOU1 CLASP2 NHLRC2 BCR BIRC6 MELK ARID1B EIF4ENIF1 CEP135 NFRKB XRN1 ANKRD28 DNAJC1 CDK11B WDR62	3.54e-06	733	170	15	34672954
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZNF449 BEST1 ABAT NEK6 PPFIBP2 SGTA SRPK2 CLASP2 CHD1L BCR PPP1CB FOXP4 PTPRE COQ8A PIK3C3 TLL1 EHMT1 MACF1 SEMA6A ADI1 ICA1L ARAP1	3.95e-06	1489	170	22	28611215
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	HYOU1 MAK16 ACTN4 PRPF8 THOC2 BIRC6 PPP1CB NEFM UBR5 XRN1 ANKRD28 MACF1 ATM COIL	4.47e-06	653	170	14	22586326
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	REPS1 SGCB ACTN4 CLASP2 BIRC6 PPP1CB STRADB ARID1B UPF2 ZBTB40 ANKRD28 MACF1	6.77e-06	497	170	12	23414517
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	EPS8 HTRA1 HYOU1 ANKS1B SRPK2 ACTN4 CLASP2 COPS3 BCR PPP1CB PIK3R4 NEFM CDKL5 SLC25A12 UPF2 NMT2 ITSN2 XRN1 SLC17A7 MACF1 DNAH11	7.40e-06	1431	170	21	37142655
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	GLT8D2 LRRK2 GXYLT1 ZNF510 ZNF229 ATXN1L ZIM3 ADAM28 SEMA3D SLC25A12 UBXN7 ANKRD28 SEMA6A ICA1L	7.82e-06	686	170	14	29987050
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	FRAS1 HTRA1 SLC25A12 HMCN1 MACF1 PLS1 DNAH11	1.05e-05	152	170	7	34299191
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NRBP1 FRAS1 HYOU1 VWA8 SGTA SRPK2 CLASP2 ZDHHC17 PRPF8 PCF11 DNAJC10 UBR5 EHMT1 ANKRD28 MACF1 SEMA6A DNAJC1 ATM ADI1 OGA WDR62	1.32e-05	1487	170	21	33957083
Pubmed	Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.	PLXND1 NEFM SEMA3D	1.34e-05	10	170	3	15550623
Pubmed	Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects.	PLXND1 NEFM FOXP4	1.34e-05	10	170	3	18992737
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	DDX19A MAK16 CLASP2 CHD1L FOXP4 NFATC2 ATM CDK11B COIL TAF1L	1.55e-05	370	170	10	22922362
Pubmed	A protein interaction landscape of breast cancer.	HYOU1 VWA8 MUC5B COPS3 PPP1CB STRADB ARID1B SLC25A12 BRCA1 UBR5 ANKRD28 MACF1 RPA3	1.59e-05	634	170	13	34591612
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FRAS1 HYOU1 SRPK2 ZDHHC17 BCR PIK3R4 CLCN3 DNAJC10 UPF2 COQ8A TLL1 XRN1 ANKRD28	2.06e-05	650	170	13	38777146
Pubmed	ADAD2 functions in spermiogenesis and piRNA biogenesis in mice.	ADAD1 ADAD2	2.38e-05	2	170	2	36698249
Pubmed	Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity.	BRCA1 ATM	2.38e-05	2	170	2	21849032
Pubmed	Concomitant loss of heterozygosity at the BRCA1 and FHIT genes as a prognostic factor in sporadic breast cancer.	BRCA1 FHIT	2.38e-05	2	170	2	20417865
Pubmed	Constitutive activation of the ATM/BRCA1 pathway prevents DNA damage-induced apoptosis in 5-azacytidine-resistant cell lines.	BRCA1 ATM	2.38e-05	2	170	2	24680865
Pubmed	Human intersectin 2 (ITSN2) binds to Eps8 protein and enhances its degradation.	EPS8 ITSN2	2.38e-05	2	170	2	22449706
Pubmed	Quantitative detection of methylation of FHIT and BRCA1 promoters in the serum of ductal breast cancer patients.	BRCA1 FHIT	2.38e-05	2	170	2	26406001
Pubmed	hVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cells.	PIK3R4 PIK3C3	2.38e-05	2	170	2	18957027
Pubmed	CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing.	TREX1 CDK11B	2.38e-05	2	170	2	26567509
Pubmed	Impaired skin and mammary gland development and increased gamma-irradiation-induced tumorigenesis in mice carrying a mutation of S1152-ATM phosphorylation site in Brca1.	BRCA1 ATM	2.38e-05	2	170	2	19996295
Pubmed	LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies.	LRRK2 NFATC2	2.38e-05	2	170	2	33055242
Pubmed	E3 ubiquitin ligase UBR5 promotes gemcitabine resistance in pancreatic cancer by inducing O-GlcNAcylation-mediated EMT via destabilization of OGA.	UBR5 OGA	2.38e-05	2	170	2	38755129
Pubmed	Comparison of collagen propeptides as growth markers in children with inflammatory bowel disease.	BRCA1 ATM	2.38e-05	2	170	2	2001833
Pubmed	Identification of EPS8 as a Dvl1-associated molecule.	EPS8 DVL1	2.38e-05	2	170	2	10581192
Pubmed	Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.	DVL1P1 DVL1	2.38e-05	2	170	2	8644734
Pubmed	A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.	ANKS1B COIL	2.38e-05	2	170	2	15862129
Pubmed	Integrin β4 regulates SPARC protein to promote invasion.	SPARC ITGB4	2.38e-05	2	170	2	22308039
Pubmed	Prostaglandin F2alpha promotes muscle cell survival and growth through upregulation of the inhibitor of apoptosis protein BRUCE.	BIRC6 NFATC2	2.38e-05	2	170	2	18566603
Pubmed	ANKS1B is a smoking-related molecular alteration in clear cell renal cell carcinoma.	ANKS1B EYS	2.38e-05	2	170	2	24479813
Pubmed	Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers.	BRCA1 ATM	2.38e-05	2	170	2	29665859
Pubmed	High expression of PI3K core complex genes is associated with poor prognosis in chronic lymphocytic leukemia.	PIK3R4 PIK3C3	2.38e-05	2	170	2	25840748
Pubmed	Role for ATM in DNA damage-induced phosphorylation of BRCA1.	BRCA1 ATM	2.38e-05	2	170	2	10866324
Pubmed	Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer.	BRCA1 ATM	2.38e-05	2	170	2	16533773
Pubmed	Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching.	BRCA1 ATM	2.38e-05	2	170	2	16204043
Pubmed	Loss of ABAT-Mediated GABAergic System Promotes Basal-Like Breast Cancer Progression by Activating Ca2+-NFAT1 Axis.	ABAT NFATC2	2.38e-05	2	170	2	30662552
Pubmed	BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function.	BRCA1 FHIT	2.38e-05	2	170	2	15254237
Pubmed	A chloride conductance in VGLUT1 underlies maximal glutamate loading into synaptic vesicles.	CLCN3 SLC17A7	2.38e-05	2	170	2	19169251
Pubmed	Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.	BRCA1 ATM	2.38e-05	2	170	2	10550055
Pubmed	Hemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis.	BRCA1 ATM	2.38e-05	2	170	2	20175908
Pubmed	Identification of glycosyltransferase 8 family members as xylosyltransferases acting on O-glucosylated notch epidermal growth factor repeats.	GXYLT1 GXYLT2	2.38e-05	2	170	2	19940119
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	TBPL2 PRPF8 BCR GTF2H3 UBR5 ACTR6 NFRKB CDK11B PPIH TAF1L	2.43e-05	390	170	10	17643375
Pubmed	Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities.	DCP2 UPF2 XRN1	2.44e-05	12	170	3	14527413
Pubmed	High-resolution mapping of mouse chromosome 8 identifies an evolutionary chromosomal breakpoint.	FAT1 CLCN3 TLL1	2.44e-05	12	170	3	9680377
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	NRBP1 DDX19A HYOU1 PSMA3 ACTN4 NHLRC2 PRPF8 BCR MTMR7 DNAJC10 UBR5 UBXN7 XRN1 PUS1 ANKRD28 PLS1	2.55e-05	974	170	16	28675297
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CYP2C18 SGTA PSMA3 THOC2 PPP1CB PCF11 NFRKB ZBTB40 ATM CDK11B COIL DNMBP OGA WDR62	2.97e-05	774	170	14	15302935
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	NRBP1 DDX19A HYOU1 SGTA PSMA3 ACTN4 COPS3 NHLRC2 PPAT BIRC6 PPP1CB UBXN7 NFRKB PUS1 ANKRD28 MACF1 DNMBP OGA RPA3 PLS1	3.15e-05	1455	170	20	22863883
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	HYOU1 NEK6 PSMA3 ACTN4 COPS3 PPAT THOC2 ATXN1L PPWD1 PCF11 ARID1B BRCA1 UBR5 NFRKB ZBTB40 EHMT1 PPIH	3.16e-05	1103	170	17	34189442
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	ABAT RAPGEF1 CSMD2 THOC2 CDKL5 BRCA1 CELSR2 PDIA2 ATP2A3	3.78e-05	329	170	9	17474147
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	DDX19A PDSS2 HYOU1 VWA8 PSMA3 FASTKD1 DVL1 SRPK2 ZDHHC17 PPAT BIRC6 SLC25A12 EIF4ENIF1 UPF2 ITSN2 PUS1 DNAJC1 COIL RPA3 WDR62	4.63e-05	1496	170	20	32877691
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DDX19A VWA8 PSMA3 CHD1L BCR PPP1CB SLC25A12 DNAJC10 COQ8A ANKRD28 SLC25A19 WDR62	4.74e-05	606	170	12	36538041
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	DDX19A SGTA PSMA3 CHD1L PPAT PRPF8 THOC2 BIRC6 PPP1CB PIK3R4 SLC25A12 PELO DNAJC10 COQ8A UBR5 PPIH SLC25A19 OGA	4.76e-05	1257	170	18	37317656
Pubmed	C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development.	RAPGEF1 NEFM TBR1	5.00e-05	15	170	3	27111087
Pubmed	Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology.	PELO UPF2 TBR1	5.00e-05	15	170	3	33899734
Pubmed	Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.	BRCA1 ATM TBR1	5.00e-05	15	170	3	27073218
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	HYOU1 SGTA PSMA3 SRPK2 ACTN4 CLASP2 COPS3 NHLRC2 PRPF8 PPP1CB NEFM PELO UBR5 MACF1 PPIH OGA RPA3	5.24e-05	1149	170	17	35446349
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	DCP2 CLASP2 COPS3 PRPF8 PPP1CB PCF11 ARID1B UBR5 ITSN2 CEP135 EHMT1 ATM COIL PPIH RPA3 WDR62 ARAP1	5.58e-05	1155	170	17	20360068
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	NEFM SEMA3D SEMA6A	6.13e-05	16	170	3	22632726
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXND1 NEFM SEMA3D	6.13e-05	16	170	3	18489001
Pubmed	Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size.	NEFM TBR1 WDR62	6.13e-05	16	170	3	24875059
Pubmed	Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb.	NEFM SLC17A7 TBR1	6.13e-05	16	170	3	22745484
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	HYOU1 DVL1 PRPF8 BCR GTF2H3 EIF4ENIF1 BRCA1 UPF2 XRN1 EHMT1 MACF1 TAGLN DNMBP	6.20e-05	724	170	13	36232890
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	VWA8 PLXND1 BCR MELK ARID1B COQ8A UBXN7 EHMT1 DNMBP OGA ARAP1	6.39e-05	529	170	11	14621295
Pubmed	Defining the membrane proteome of NK cells.	DDX19A HYOU1 CLASP2 PRPF8 BCR BIRC6 MELK PIK3R4 CLCN3 EIF4ENIF1 DNAJC10 UBR5 PIK3C3 XRN1 DNAJC1 COIL OGA	6.40e-05	1168	170	17	19946888
Pubmed	Vesicular glutamate transporters use flexible anion and cation binding sites for efficient accumulation of neurotransmitter.	CLCN3 SLC17A7	7.10e-05	3	170	2	25433636
Pubmed	Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study.	BRCA1 ATM	7.10e-05	3	170	2	15084244
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	NEFM MACF1	7.10e-05	3	170	2	12399109
Pubmed	Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9.	PIK3R4 PIK3C3	7.10e-05	3	170	2	14751759
Pubmed	A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.	BRCA1 ATM	7.10e-05	3	170	2	12773400
Pubmed	Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.	BRCA1 ATM	7.10e-05	3	170	2	11114888
Pubmed	CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.	CDKL5 SLC17A7	7.10e-05	3	170	2	22922712
Pubmed	Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response.	BRCA1 ATM	7.10e-05	3	170	2	10910365
Pubmed	Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy.	BRCA1 ATM	7.10e-05	3	170	2	25205036
Pubmed	Screening for ATM sequence alterations in African-American women diagnosed with breast cancer.	BRCA1 ATM	7.10e-05	3	170	2	17333338
Pubmed	EDD inhibits ATM-mediated phosphorylation of p53.	UBR5 ATM	7.10e-05	3	170	2	21383020
Pubmed	ATR/ATM-Mediated Phosphorylation of BRCA1 T1394 Promotes Homologous Recombinational Repair and G2-M Checkpoint Maintenance.	BRCA1 ATM	7.10e-05	3	170	2	34301763
Pubmed	Is olaparib cost effective in metastatic castration-resistant prostate cancer patients with at least one favorable gene mutation in BRCA1, BRCA2 or ATM?	BRCA1 ATM	7.10e-05	3	170	2	34517749
Pubmed	Effect of DNA damage on a BRCA1 complex.	BRCA1 ATM	7.10e-05	3	170	2	11689934
Pubmed	Presynaptic CLC-3 determines quantal size of inhibitory transmission in the hippocampus.	CLCN3 SLC17A7	7.10e-05	3	170	2	21378974
Pubmed	BRCA1 affects protein phosphatase 6 signalling through its interaction with ANKRD28.	BRCA1 ANKRD28	7.10e-05	3	170	2	27026398
Pubmed	Variants in the ATM-CHEK2-BRCA1 axis determine genetic predisposition and clinical presentation of papillary thyroid carcinoma.	BRCA1 ATM	7.10e-05	3	170	2	24599715
Pubmed	DNA Repair Deficiency Is Common in Advanced Prostate Cancer: New Therapeutic Opportunities.	BRCA1 ATM	7.10e-05	3	170	2	27317574
Pubmed	UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function.	UBR5 ATM	7.10e-05	3	170	2	25092319
Pubmed	Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase.	BRCA1 ATM	7.10e-05	3	170	2	23509290
Pubmed	Simultaneous ATM/BRCA1/RAD51 expression variations associated with prognostic factors in Iranian sporadic breast cancer patients.	BRCA1 ATM	7.10e-05	3	170	2	28058614
Pubmed	ATM-dependent activation of SIM2s regulates homologous recombination and epithelial-mesenchymal transition.	BRCA1 ATM	7.10e-05	3	170	2	30531838
Pubmed	ATM loss leads to synthetic lethality in BRCA1 BRCT mutant mice associated with exacerbated defects in homology-directed repair.	BRCA1 ATM	7.10e-05	3	170	2	28659469
Pubmed	Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in Apc(Min)/+ mice.	BRCA1 ATM	7.10e-05	3	170	2	11181458
Pubmed	Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies.	BRCA1 ATM	7.10e-05	3	170	2	11278964
Interaction	XAGE2 interactions	EPS8 GMCL2 FOXP4 EHMT1	5.65e-06	15	166	4	int:XAGE2
GeneFamily	Glycosyltransferase family 8	GLT8D2 GXYLT1 GXYLT2	2.05e-05	9	115	3	436
GeneFamily	EF-hand domain containing	EFCAB5 REPS1 RYR2 SLC25A12 ITSN2 MACF1 PLS1	5.04e-04	219	115	7	863
GeneFamily	Classical BAR domain containing	DNMBP ICA1L	1.10e-03	8	115	2	1292
GeneFamily	Adenosine deaminases acting on RNA	ADAD1 ADAD2	1.10e-03	8	115	2	1303
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	EPS8 SRPK2 CLASP2 ZDHHC17 THOC2 MELK PIK3R4 PCF11 FAT1 SLC25A12 BRCA1 UPF2 UBR5 PIK3C3 NMT2 ITSN2 UBXN7 CEP135 ANKRD28 MACF1 DNMBP	1.67e-07	856	169	21	M4500
Coexpression	GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP	GRK4 RYR2 CDKL5 DENND10 UBR5 CEP135 WDR35 ADI1 DNMBP	1.38e-06	166	169	9	M344
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	EPS8 SRPK2 CLASP2 ZDHHC17 MELK FAT1 BRCA1 UPF2 UBR5 PIK3C3 NMT2 ITSN2 CEP135 DNMBP	2.16e-06	466	169	14	M13522
Coexpression	GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN	UPB1 HYOU1 MAK16 BRCA1 ACTR6 ATM COIL EPHX4 ATP2A3	6.13e-06	199	169	9	M9170
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	GXYLT1 PRPF8 BIRC6 BRCA1 CELSR2 ZBTB40 MACF1 ATM	2.31e-05	180	169	8	M8239
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 MUC5B RYR2 COL24A1 HMCN1 TLL1 ABCC12 HEPHL1	1.84e-07	160	169	8	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 MUC5B RYR2 COL24A1 HMCN1 TLL1 ABCC12 HEPHL1	1.84e-07	160	169	8	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 CUBN ADAM28 RYR2 COL24A1 TMC5 UNC79 DNAH11	2.80e-07	169	169	8	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 MUC5B RYR2 COL24A1 FAT1 HMCN1 UNC79 DNAH11	5.35e-07	184	169	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 MUC5B RYR2 COL24A1 FAT1 HMCN1 UNC79 DNAH11	5.35e-07	184	169	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	CYP2C18 MUC5B ITGB4 ADAM28 LGALS4 TMC5 PLS1 FRMD5	5.35e-07	184	169	8	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 MUC5B RYR2 COL24A1 FAT1 HMCN1 UNC79 DNAH11	5.35e-07	184	169	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEK6 LRRK2 CUBN HHLA2 FAT1 SEMA6A PLS1 FRMD5	5.80e-07	186	169	8	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	GLT8D2 ABAT HTRA1 SPARC GXYLT2 HMCN1 PODN TMC5	6.04e-07	187	169	8	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HTRA1 SPARC PLXND1 SEMA3D PTPRE TLL1 SEMA6A TNXB	7.98e-07	194	169	8	fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCell	metastatic_Brain-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	SH3TC2 FRAS1 COL24A1 SEMA6A EPHX4 SLC14A2 UNC79	9.98e-07	138	169	7	b2ab273f3e62f169b3b9cb82342e6617af99f582
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 GSTA3 SEMA3D PODN PLSCR2 TNXB FRMD5	4.49e-06	173	169	7	ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 GSTA3 SEMA3D PODN PLSCR2 TNXB FRMD5	4.49e-06	173	169	7	3725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 HTRA1 SPARC PPFIBP2 GSTA3 SEMA3D PODN	6.04e-06	181	169	7	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF229 RYR2 COL24A1 HMCN1 PODN TAGLN TNXB	6.04e-06	181	169	7	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 HTRA1 SPARC PPFIBP2 GSTA3 SEMA3D PODN	6.04e-06	181	169	7	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	CYP2C18 MUC5B ITGB4 LGALS4 TMC5 PLS1 FRMD5	6.50e-06	183	169	7	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 RYR2 TLL1 NMT2 SLC17A7 RAB37 UNC79	6.97e-06	185	169	7	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	RNF144B NEK6 PPFIBP2 LRRK2 ADAM28 EHMT1 DNMBP	7.48e-06	187	169	7	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPFIBP2 LRRK2 PPWD1 RYR2 HMCN1 UBR5 XRN1	7.75e-06	188	169	7	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPFIBP2 LRRK2 PPWD1 RYR2 HMCN1 UBR5 XRN1	7.75e-06	188	169	7	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPFIBP2 LRRK2 PPWD1 RYR2 HMCN1 UBR5 XRN1	7.75e-06	188	169	7	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GLT8D2 HTRA1 GXYLT2 COL24A1 SEMA3D PODN TNXB	7.75e-06	188	169	7	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLT8D2 HTRA1 SPARC GXYLT2 SEMA3D PODN TNXB	8.02e-06	189	169	7	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLT8D2 HTRA1 SPARC GXYLT2 SEMA3D PODN TNXB	8.02e-06	189	169	7	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPFIBP2 LRRK2 RAPGEF1 ADAM28 UPF2 SEMA6A DNMBP	8.30e-06	190	169	7	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGB4 SEMA3D PTPRE HMCN1 TLL1 SEMA6A TNXB	8.30e-06	190	169	7	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	COPD-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	RNF144B NEK6 PPFIBP2 RAPGEF1 ADAM28 UPF2 DNMBP	8.30e-06	190	169	7	1e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell	COPD-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	RNF144B LRRK2 PPP1CB DENND10 RAB37 DNMBP ICA1L	8.30e-06	190	169	7	aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	CLASP2 PPP1R3C COL24A1 SEMA3D MACF1 OGA UTY	8.30e-06	190	169	7	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLT8D2 HTRA1 SPARC GXYLT2 PODN TAGLN TNXB	8.89e-06	192	169	7	c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell	-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	RYR2 SEMA3D NFATC2 SLIT1 PODN ATP2A3 TNXB	9.83e-06	195	169	7	e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLT8D2 HTRA1 SPARC GXYLT2 PODN TAGLN TNXB	9.83e-06	195	169	7	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	SPARC PLXND1 SEMA3D PTPRE TLL1 SEMA6A TNXB	1.02e-05	196	169	7	ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HTRA1 SPARC PLXND1 SEMA3D TLL1 SEMA6A TNXB	1.02e-05	196	169	7	95c5b8fd4ebfae1f42de9b1475c1161d4a80e515
ToppCell	AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	EPS8 HTRA1 MUC5B C1QL2 FAT1 HMCN1 TMC5	1.05e-05	197	169	7	5e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GLT8D2 GXYLT2 COL24A1 HMCN1 PODN ABCC12 TNXB	1.05e-05	197	169	7	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	VWA8 CLASP2 BIRC6 ARID1B UBR5 FHIT UTY	1.12e-05	199	169	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	EPS8 PPFIBP2 RYR2 PPP1R3C FAT1 PELO TAGLN	1.16e-05	200	169	7	4e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FRAS1 SPARC RYR2 PPP1R3C HMCN1 MACF1 TNXB	1.16e-05	200	169	7	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	4dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TNXB	1.16e-05	200	169	7	137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FRAS1 SPARC RYR2 PPP1R3C HMCN1 MACF1 TNXB	1.16e-05	200	169	7	a510deaada669e690329183e18df02870bd204b3
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	8256511b099c3eab8e33194f90c9ff354e7cfe8e
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	EPS8 PPFIBP2 RYR2 PPP1R3C FAT1 PELO TAGLN	1.16e-05	200	169	7	786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TREX1 SPARC NEK6 GXYLT1 CSMD2 ITSN2 MDH1B	1.16e-05	200	169	7	b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TNXB	1.16e-05	200	169	7	25d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	EFCAB5 EPS8 PPFIBP2 RYR2 FAT1 PELO TAGLN	1.16e-05	200	169	7	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	367C-Fibroblasts\|367C / Donor, Lineage, Cell class and subclass (all cells)	GLT8D2 HTRA1 SPARC SGCB HMCN1 PODN TAGLN	1.16e-05	200	169	7	c5aaa20c59b9f11b8abdf5de9e3fc54f4e6e39f7
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	e663995fc44c340d878d66b278b7b5c2ff784301
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TNXB	1.16e-05	200	169	7	c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-4\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	2cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCell	Lung_Parenchyma-Severe-Mesenchymal\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	6ce8e2cf689523993d909a27daec3d6a5824d13c
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	907427e85cebe5a18c8a310e2ffa0e180ea3cb77
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	8cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell	Parenchyma_COVID-19-Stromal-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	GLT8D2 HTRA1 SPARC GXYLT2 HMCN1 PODN TAGLN	1.16e-05	200	169	7	8472baa74c48b67c5f08223025885c833458290b
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FRAS1 SPARC RYR2 PPP1R3C HMCN1 MACF1 TNXB	1.16e-05	200	169	7	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	EFCAB5 CSMD2 EYS UBR5 NFRKB ZBTB40	1.29e-05	135	169	6	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175\|Adult / Lineage, Cell type, age group and donor	EPS8 PPAT FAT1 HMCN1 TMC5 SLC27A5	2.35e-05	150	169	6	b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABAT GSTA3 PPP1R3C COQ8A SLC25A19 SLC27A5	2.73e-05	154	169	6	a5289000597068ee8d559f89bce7bce31f35dd57
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	EFCAB5 NEFM SLIT1 TBR1 EPHX4 SLC27A5	3.75e-05	163	169	6	218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCell	facs-Skin-Anagen-24m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3TC2 STRADB CELSR2 SEMA6A FHIT	3.98e-05	100	169	5	97ca9cda55a05fbb4d1f5d61f847c965e014f05c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L5_RORB_SNHG7\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NEFM COL24A1 SEMA3D TLL1 ABCC12 TMC5	4.29e-05	167	169	6	5d89f5bcd0aaa772c1d09c2cc46fbfe0a90f9f12
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGB4 SEMA3D PTPRE TLL1 SEMA6A TNXB	4.74e-05	170	169	6	6035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGB4 SEMA3D PTPRE TLL1 SEMA6A TNXB	4.74e-05	170	169	6	c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGB4 SEMA3D PTPRE TLL1 SEMA6A TNXB	4.74e-05	170	169	6	dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GLT8D2 HTRA1 SGCB ANKS1B TAGLN WDR62	5.39e-05	174	169	6	7fb7bdf62563f2102fb38618b503eb2817b6594f
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 PPFIBP2 SEMA3D TLL1 PODN TNXB	5.39e-05	174	169	6	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	PDSS2 HYOU1 COL24A1 CLCN3 NFATC2 WDR35	5.39e-05	174	169	6	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL24A1 HMCN1 PODN MACF1 TAGLN TNXB	5.57e-05	175	169	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKS1B RYR2 LGALS4 ABCC12 UNC79 TNXB	5.57e-05	175	169	6	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 RYR2 HMCN1 XRN1 PODN MACF1	5.75e-05	176	169	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 LRRK2 ANKS1B SEMA3D MACF1 SEMA6A	6.51e-05	180	169	6	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTRA1 LRRK2 ANKS1B SEMA3D MACF1 SEMA6A	6.51e-05	180	169	6	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	ARID1B UBR5 MACF1 ATM OGA UTY	6.71e-05	181	169	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKS1B RYR2 COL24A1 PODN TNXB FRMD5	7.13e-05	183	169	6	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPS8 SPARC PPFIBP2 RYR2 PELO TAGLN	7.13e-05	183	169	6	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLT8D2 HTRA1 SPARC PODN TAGLN TNXB	7.13e-05	183	169	6	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BCR ITGB4 PTPRE TLL1 SEMA6A TNXB	7.13e-05	183	169	6	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	RNF144B LRRK2 PPP1CB DENND10 PTPRE DNMBP	7.35e-05	184	169	6	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	Posterior_cortex-Neuronal-Excitatory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GLT8D2 RYR2 NEFM SLC17A7 TBR1 EPHX4	7.35e-05	184	169	6	25ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPS8 SPARC PPFIBP2 RYR2 FAT1 TAGLN	7.35e-05	184	169	6	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLT8D2 SPARC PPP1R3C HMCN1 TAGLN TNXB	7.57e-05	185	169	6	7b1c5d99bd7a6e148524029758cee244a17f5d09
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 NEFM TLL1 NMT2 SLC17A7 RAB37	7.57e-05	185	169	6	70de48988c1f8e0809afc8092b663aa439d8e528
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLT8D2 SPARC PPP1R3C HMCN1 TAGLN TNXB	7.57e-05	185	169	6	e9033a03d574956cf3ae228740b3166e40a6397f
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLT8D2 SPARC PPP1R3C HMCN1 TAGLN TNXB	7.57e-05	185	169	6	578f12c6b2e33d09598dc8e022a20c8555d1325c
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL24A1 XRN1 EHMT1 ANKRD28 DNAJC1 ATM	7.57e-05	185	169	6	3b77bc49cd3740acc025e162a36282ac09e12198
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKS1B COL24A1 PODN TAGLN TNXB FRMD5	7.57e-05	185	169	6	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MUC5B MELK LGALS4 HHLA2 TMC5 WDR62	7.57e-05	185	169	6	4d0f3d86fab02c80093e62cb0c79c586c13c5412
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPFIBP2 CSMD2 RYR2 PPP1R3C FAT1 TAGLN	7.80e-05	186	169	6	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NEK6 ANKS1B CUBN HHLA2 FHIT PLS1	7.80e-05	186	169	6	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 LRRK2 ANKRD28 TMC5 PLS1 FRMD5	7.80e-05	186	169	6	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPFIBP2 CSMD2 RYR2 PPP1R3C FAT1 TAGLN	7.80e-05	186	169	6	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 NEFM TLL1 SLC17A7 RAB37 UNC79	8.03e-05	187	169	6	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 CUBN ADAM28 FAT1 TLL1 TMC5	8.03e-05	187	169	6	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HYOU1 NHLRC2 ZDHHC17 COL24A1 ZNF530 UTY	8.03e-05	187	169	6	d3563bb087e476baea5b59389e4d34d0ff98cac5
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	ANKS1B CLASP2 RYR2 SEMA3D MACF1 TAGLN	8.27e-05	188	169	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)\|390C / Donor, Lineage, Cell class and subclass (all cells)	GLT8D2 HTRA1 SEMA3D TLL1 SEMA6A TNXB	8.27e-05	188	169	6	aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	GLT8D2 HTRA1 SEMA3D TLL1 SEMA6A TNXB	8.27e-05	188	169	6	1f40b959777d18ad88d239df8cca304f062ba04c
Computational	B lymphoma expression clusters.	CSMD2 ADAM28 ANKRD28 ATP2A3 UTY ALOX5 SLC27A5 DNAH11	1.08e-04	149	106	8	MODULE_361
Computational	Genes in the cancer module 301.	CSMD2 ADAM28 ANKRD28 ATP2A3 UTY ALOX5 SLC27A5 DNAH11	1.63e-04	158	106	8	MODULE_301
Computational	Genes in the cancer module 238.	CSMD2 ADAM28 ANKRD28 ATP2A3 UTY ALOX5 SLC27A5 DNAH11	2.10e-04	164	106	8	MODULE_238
Disease	nephrotic syndrome (implicated_via_orthology)	FAT1 COQ8A ITSN2 ALOX5	9.18e-06	24	165	4	DOID:1184 (implicated_via_orthology)
Disease	invasive ductal carcinoma (is_implicated_in)	ADAM28 UBR5 FHIT	2.74e-05	11	165	3	DOID:3008 (is_implicated_in)
Disease	Prostatic Neoplasms	CYP2C18 PPFIBP2 ADAM28 FOXP4 DNAJC10 BRCA1 ITSN2 IRAK4 ATM ADI1 FHIT TAF1L ALOX5	4.64e-05	616	165	13	C0033578
Disease	Malignant neoplasm of prostate	CYP2C18 PPFIBP2 ADAM28 FOXP4 DNAJC10 BRCA1 ITSN2 IRAK4 ATM ADI1 FHIT TAF1L ALOX5	4.64e-05	616	165	13	C0376358
Disease	Intervertebral Disc Degeneration	HTRA1 SPARC	9.29e-05	3	165	2	C0158266
Disease	alcohol use disorder (implicated_via_orthology)	EPS8 GRK4 RYR2 PPP1R3C ARID1B UNC79 UTY	1.19e-04	195	165	7	DOID:1574 (implicated_via_orthology)
Disease	lung non-small cell carcinoma (is_implicated_in)	ADAM28 FAT1 ARID1B BRCA1 ATM FHIT	1.36e-04	139	165	6	DOID:3908 (is_implicated_in)
Disease	neurodegenerative disease (implicated_via_orthology)	TBPL2 DVL1P1 PSMA3 LRRK2 DVL1 SLC17A7	1.71e-04	145	165	6	DOID:1289 (implicated_via_orthology)
Disease	whole-brain volume	CUBN DNAH11	3.07e-04	5	165	2	EFO_0005089
Disease	response to platinum based chemotherapy, cytotoxicity measurement	FRAS1 EYS	3.07e-04	5	165	2	EFO_0004647, EFO_0006952
Disease	DiGeorge syndrome (is_implicated_in)	DVL1P1 DVL1	3.07e-04	5	165	2	DOID:11198 (is_implicated_in)
Disease	vitelliform macular dystrophy (is_implicated_in)	BEST1 HTRA1	3.07e-04	5	165	2	DOID:0050661 (is_implicated_in)
Disease	lung non-small cell carcinoma (is_marker_for)	HTRA1 ADAM28 BRCA1 UBR5 ATM FHIT	3.90e-04	169	165	6	DOID:3908 (is_marker_for)
Disease	retinitis pigmentosa	EYS DNAJC10	4.59e-04	6	165	2	MONDO_0019200
Disease	Benign Neoplasm	BIRC6 DNAJC10 BRCA1 ATM	5.81e-04	68	165	4	C0086692
Disease	Neoplasms	BIRC6 DNAJC10 BRCA1 ATM	5.81e-04	68	165	4	C0027651
Disease	intellectual disability (is_implicated_in)	CDKL5 ARID1B WDR62	6.24e-04	30	165	3	DOID:1059 (is_implicated_in)
Disease	coenzyme Q10 deficiency disease (implicated_via_orthology)	PDSS2 COQ8A	6.41e-04	7	165	2	DOID:0050730 (implicated_via_orthology)
Disease	atrioventricular septal defect (implicated_via_orthology)	MKS1 DNAH11	6.41e-04	7	165	2	DOID:0050651 (implicated_via_orthology)
Disease	Ovarian Mucinous Adenocarcinoma	NRBP1 LRRK2 MELK	6.88e-04	31	165	3	C1335167
Disease	Huntington's disease (implicated_via_orthology)	ABAT ZDHHC17 PLS1	7.56e-04	32	165	3	DOID:12858 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_marker_for)	HTRA1 FAT1 EHMT1 ATM	8.00e-04	74	165	4	DOID:3748 (is_marker_for)
Disease	response to serotonin-norephinephrine reuptake inhibitor	BIRC6 NFATC2 ARAP1	1.07e-03	36	165	3	EFO_0006325
Disease	esophagus squamous cell carcinoma (is_implicated_in)	HTRA1 FAT1 BRCA1	2.05e-03	45	165	3	DOID:3748 (is_implicated_in)
Disease	Adenoid Cystic Carcinoma	ITGB4 FAT1 BRCA1 ATM	2.44e-03	100	165	4	C0010606
Disease	lung adenocarcinoma (is_implicated_in)	HTRA1 ADAM28 UBR5	2.62e-03	49	165	3	DOID:3910 (is_implicated_in)
Disease	ocular hypertension, response to triamcinolone acetonide	VWA8 ITGB4 COL24A1	2.62e-03	49	165	3	EFO_0006954, EFO_1001069
Disease	level of Phosphatidylethanolamine (18:2_0:0) in blood serum	NRBP1 BEST1	2.71e-03	14	165	2	OBA_2045143
Disease	sitting height ratio	ARID1B NFATC2 ITSN2	2.94e-03	51	165	3	EFO_0007118
Disease	Autosomal recessive primary microcephaly	CEP135 WDR62	3.11e-03	15	165	2	cv:C3711387
Disease	cerebellum white matter volume change measurement	FHIT SLC27A5	3.54e-03	16	165	2	EFO_0021498
Disease	coffee consumption, cups of coffee per day measurement	EFCAB5 PDSS2	3.54e-03	16	165	2	EFO_0004330, EFO_0006782
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	UBR5 ATM	3.54e-03	16	165	2	C0334634
Disease	Autistic Disorder	ABAT UPB1 VWA8 SLC25A12 TPH2 TBR1	3.59e-03	261	165	6	C0004352
Disease	cortical surface area measurement	EFCAB5 REPS1 SRPK2 ACTN4 PLXND1 BCR COL24A1 SEMA3D ARID1B TLL1 XRN1 MACF1 SEMA6A TNXB PLS1 DNAH11	3.69e-03	1345	165	16	EFO_0010736
Disease	essential hypertension, age at diagnosis	GXYLT1 DNAJC1 UNC79	3.83e-03	56	165	3	EFO_0004918, MONDO_0001134
Disease	Beta blocking agent use measurement	NHLRC2 CELSR2 NFATC2 SLC14A2	3.90e-03	114	165	4	EFO_0009929
Disease	Benign neoplasm of stomach	UBR5 ATM	4.00e-03	17	165	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	UBR5 ATM	4.00e-03	17	165	2	C0496905
Disease	Carcinoma in situ of stomach	UBR5 ATM	4.00e-03	17	165	2	C0154060
Disease	caudal anterior cingulate cortex volume measurement	SPARC FHIT	4.00e-03	17	165	2	EFO_0010289
Disease	ischemia (implicated_via_orthology)	ABAT ARID1B	4.00e-03	17	165	2	DOID:326 (implicated_via_orthology)
Disease	urate measurement, spine bone mineral density	SH3TC2 FHIT SLC27A5	4.23e-03	58	165	3	EFO_0004531, EFO_0007701
Disease	information processing speed, response to cranial radiation therapy	PPFIBP2 NMT2 SLIT1	4.23e-03	58	165	3	EFO_0004363, EFO_0010950
Disease	Age-related macular degeneration	HTRA1 HMCN1	4.48e-03	18	165	2	cv:C0242383
Disease	Hallux valgus	COL24A1 EYS SLIT1	4.65e-03	60	165	3	HP_0001822
Disease	sleep duration, high density lipoprotein cholesterol measurement	CELSR2 MACF1 FHIT FRMD5	4.82e-03	121	165	4	EFO_0004612, EFO_0005271
Disease	Pancreatic carcinoma	BRCA1 ALOX5	4.99e-03	19	165	2	C0235974
Disease	anorectal malformation	MUC5B CSMD2	4.99e-03	19	165	2	MONDO_0019938
Disease	Adenocarcinoma of prostate	BRCA1 ATM	5.53e-03	20	165	2	C0007112
Disease	hip bone mineral density	TBPL2 NRBP1 NMT2 DNAH11	5.56e-03	126	165	4	EFO_0007702

Protein segments in the cluster

Peptide	Gene	Start	Entry
PGFHTNKNIYSRDIE	nan	601	A8MVM7
NAGALSAHRYFRDNP	ACTR6	126	Q9GZN1
DENKLLHPFVFGQYR	DENND10P1	51	Q6NSW5
AFHQAARAVGKPYLL	ADAD2	526	Q8NCV1
HSVRFNPNLYNDGKV	BIRC6	4651	Q9NR09
DHSQNRPGFKLEYQD	CSMD2	2061	Q7Z408
RFIKPLSNAYHELAQ	COPS3	251	Q9UNS2
IHRDGQEHALFKYNP	ADAM28	146	Q9UKQ2
IHKEFYDGLFPRVQQ	BCR	556	P11274
IDQLHLEYAKRAAPF	ACTN4	526	O43707
FQDNEKRTPLHAAAY	ANKRD28	36	O15084
DKNGNTPLHIAARYG	ANKRD28	336	O15084
NFASLRYLFLGNPDH	DNAH11	651	Q96DT5
NYSQDIKPDGRVLHD	ADAD1	256	Q96M93
DELPKFHQYAQGLFT	DNMBP	1166	Q6XZF7
QFLNPAKAYPGHELD	BEST1	256	O76090
YEVGDPSQKALDHNA	ARID1B	1771	Q8NFD5
FSEHPYNNLRKRFGA	CDK11B	676	P21127
DGLLLYNGRFNEKHD	CELSR2	1401	Q9HCU4
HPRKLQDNFETDAVY	DCP2	356	Q8IU60
RYHGNKALEALESFP	PDSS2	366	Q86YH6
KALPHLIQDAGQFYA	DNAJC1	236	Q96KC8
EGPHINFYQLRNFLK	ATP2A3	861	Q93084
EVVYEKANPNEHRFG	MKRN4P	321	Q13434
NGLPAFNEFYAHNAR	MUC5B	211	Q9HC84
YRGPFADENFKLRHS	PPIH	91	O43447
LKYRAGHQADEPSFQ	RAB37	191	Q96AX2
HDRQFDNLKPSGGYI	ITSN2	26	Q9NZM3
GLDRFKVYANGQHLF	LGALS4	281	P56470
QGYAHRDLKPENLLF	MELK	126	Q14680
LDNDIFLRHYDKGPC	RNF144B	226	Q7Z419
NVADNKGYFPIHLAA	ANKS1B	86	Q7Z6G8
DSHPFGYNLTLQAKD	FAT1	326	Q14517
GTADERILKPHAFYQ	NFATC2	461	Q13469
GLPEKAFEHLTNLNY	PODN	136	Q7Z5L7
VYLHNNKLADAGLPD	PODN	196	Q7Z5L7
RQKDYFIATQGPLAH	PTPRE	491	P23469
SHRAFVVKYAPGQDL	OGFOD2	216	Q6N063
LLDRNQPEVTDKYFH	FRAS1	3761	Q86XX4
GDIYNFPIHAFDKAL	MAK16	176	Q9BXY0
QPLAADGILFYAAQH	EYS	2746	Q5T1H1
FRDGHFNPEVVKYRQ	NFRKB	111	Q6P4R8
GPARNIDEAAKHRYQ	NMT2	106	O60551
FNHRYGNLDGDPKEI	MTMR7	381	Q9Y216
GETDAPIHRQNYKLD	EPHX4	131	Q8IUS5
LAEKSQARGFYPQSH	ATXN1L	386	P0C7T5
HKEEFRPNAPYRIFN	ABAT	366	P80404
RYFPAFEKVLQSHGQ	GSTA3	131	Q16772
VNFGYIEHGEKRNAL	FRA10AC1	191	Q70Z53
KDSRAYFHLLNQIAP	PLS1	296	Q14651
YFHLLNQIAPKGGED	PLS1	301	Q14651
KQADHLGSQAFYPGR	PLSCR2	31	Q9NRY7
NRSQGIPFLEYKHFV	PLXND1	1341	Q9Y4D7
LINSFADQRGHYPSK	GANC	841	Q8TET4
GNRGVYHDDKQPTFR	GXYLT2	361	A0PJZ3
NRGVYHDDKQPAFRA	GXYLT1	366	Q4G148
HDDKQPAFRAVYEAL	GXYLT1	371	Q4G148
KGSDHLESQDPRYAN	HHLA2	76	Q9UM44
LREPGKFDLVYHNEN	COIL	521	P38432
PERIHENGYNFKSDI	NEK6	216	Q9HC98
KFGLYHVDFNNTNRP	LCT	1331	P09848
KRGFPAIRDYHFVNA	LRRK2	1476	Q5S007
NPDARYSEHFLQEAK	GLT8D2	296	Q9H1C3
QNHEFYKNADVRPPF	FOXP4	456	Q8IVH2
KFFRNGNRTHPEEYT	PDIA2	121	Q13087
VEQRAFHDLKVAPGY	ITGB4	906	P16144
EENRNNAYPHKAGFA	NHLRC2	396	Q8NBF2
DIGLPQYKDQFHESR	PPFIBP2	641	Q8ND30
EFVAALHPNKDAYRP	MACF1	7101	Q9UPN3
AGRDDKNFHLNVYVP	HMCN1	3136	Q96RW7
EQKNLHFFAPEYGEV	NRBP1	236	Q9UHY1
PLNRASGHYFDEKNL	PCF11	1181	O94913
IKYPENFFLLRGNHE	PPP1CB	111	P62140
DNRNDTEGFKYPLGH	BRCA1	821	P38398
FRTPEKGDYNSEIHQ	CEP135	486	Q66GS9
NRDYHKAFGNLRSPG	CUBN	3396	O60494
DYFGIRFVDPDKQRH	FRMD5	56	Q7Z6J6
KHDYNGSFLALPLQD	EFCAB5	1096	A4FU69
VNNEDGAHKRYRPND	ATM	2781	Q13315
PRKAGDFHRNDSIYE	FHIT	101	P49789
KQADNPHVALYQARF	HYOU1	106	Q9Y4L1
DPNSLRHKYNFIADV	HTRA1	161	Q92743
KFDDVVTNLGNHYDP	C1QL2	176	Q7Z5L3
KNHIPRVGDFNESTY	UPB1	196	Q9UBR1
SQLRKCVDHPYLFDG	CHD1L	316	Q86WJ1
LKNAEYVRDHPQFLT	FASTKD1	86	Q53R41
YDPQQHKVALLDFGA	COQ8A	496	Q8NI60
VADYLQKNLPDFRIH	MDH1B	21	Q5I0G3
HGVIYDKASDAAPNL	HEPHL1	486	Q6MZM0
LPGSHNKIAENFAYI	CYP2C18	226	P33260
ADFKNVLSNRPVHAY	DVL1	31	O14640
KPSGDDRYNQFHIRR	IRAK4	41	Q9NWZ3
ADQGDFEKPRQYHEQ	EPS8	241	Q12929
PNAHGDFLKINRAYE	DNAJC10	71	Q8IXB1
VDKDGNPDNETYLHR	DDX19A	411	Q9NUU7
ADFKNVLSNRPVHAY	DVL1P1	31	P54792
DLKFHIYNLGNPGFD	GRK4	271	P32298
GFHPYDFVALKQLQD	ICA1L	251	Q8NDH6
SDDGTAPKENRHLYN	CDKL5	691	O76039
DENKLLHPFVFGQYR	DENND10	51	Q8TCE6
GYNLEAPDQDHAARA	RYR2	1061	Q92736
RFHPKQLYFSARQGE	EHMT1	736	Q9H9B1
RYQHPKGAPNADLIF	UPF2	1251	Q9HAU5
LNHNGYLDPKEDFKR	MROH5	616	Q6ZUA9
YLENKRDAFFPPLHQ	UTY	891	O14607
AFHLVVARKNGYDLP	REPS1	346	Q96D71
KIDHNPFAKGFRDNY	TBR1	381	Q16650
GPYDEFQRRHFVNKL	PPP1R3C	41	Q9UQK1
VHFYGKAIELNPANA	SGTA	111	O43765
KPRDLYSHAQFGDNN	TLL1	896	O43897
HLLDKPFYNDFERGA	ALOX5	36	P09917
IHANDYDQKRLFLGP	OGA	281	O60502
EKYNQRFGNDGLHEP	PUS1	341	Q9Y606
ALENNLFRAPVYLHK	TAF1L	761	Q8IZX4
FLYISPEKGIENNRH	GMCL2	506	Q8NEA9
YPVIFKHGDDLRQDQ	PIK3C3	631	Q8NEB9
YDGRGDNQPLHIFDK	PPWD1	206	Q96BP3
NFAPILAFLDHEGYA	SH3TC2	466	Q8TF17
QHEPDRAFYGLKQVE	PELO	286	Q9BRX2
GFNVNHLDIAPRYAS	SLC17A7	421	Q9P2U7
LAVTKNDGHYRGDPN	TAGLN	136	Q01995
HNSNFKAGYIPIDED	SGCB	36	Q16585
NLRGLQFKDPEHLYN	ABCC12	701	Q96J65
QFKEDSHPFDLGLYN	RPA3	86	P35244
GALYHNNEEKNRLPA	SPRYD7	106	Q5W111
RAVFNGPYAHKESAD	SEMA3D	366	O95025
NYFAPIPLEDHAENK	EIF4ENIF1	381	Q9NRA8
RYHPLFGNQEELDKA	ARAP1	651	Q96P48
DYFHIPLSEDKQGRR	ANKUB1	31	A6NFN9
GDPHELRNIFLQYAS	SLC25A12	11	O75746
LRNHFPGEAETLYNS	CLASP2	281	O75122
EAHIRLNGYPFLDAK	CLCN3	631	P51790
IRGKQPAVFNYSVHD	COL24A1	146	Q17RW2
AYRNGHFFPEQVLNK	PIK3R4	266	Q99570
AEQERQHNYLKDGPY	PRPF8	786	Q6P2Q9
HDDNGYRKLVGNNPS	ZIM3	146	Q96PE6
QDHVEPRKNSFELYG	TTLL8	511	A6PVC2
GGNKADQLDYENFRH	THOC2	1081	Q8NI27
SNFLHYQPAAELGKD	MKS1	36	Q9NXB0
HLGNPDYIDGKVNFS	RAPGEF1	996	Q13905
LAPGQTFDGEKLYQH	SLC27A5	601	Q9Y2P5
HPVELLARDFEKNYN	SPARC	211	P09486
PYDAKHANVALFADG	SEMA6A	166	Q9H2E6
YEQFNGELPNGRHKI	SRPK2	431	P78362
DHFLVQYRNGDGQPK	TNXB	2656	P22105
NKPEFDHLAEYLGAN	PPAT	441	Q06203
NESGHLNLPRFEKYL	XRN1	326	Q8IZH2
SNFGYNIPLKHLADR	PSMA3	101	P25788
DADHPGFKDNVYRQR	TPH2	176	Q8IWU9
HRINPGENGLKSNEY	ZNF229	256	Q9UJW7
AYHSRPLNDFEKILQ	ZNF862	566	O60290
HLQEARQAKGYDNPS	ZDHHC17	276	Q8IUH5
VADGLAFHAKRSYQP	WDR62	846	O43379
QRFRQYLASKHGPEA	TTLL9	276	Q3SXZ7
HVQSKGYPNERFELL	UBXN7	441	O94888
FSNQSHPKDYRGDDL	ZNF510	111	Q9Y2H8
KHGQRHRAVYDFPQF	STRADB	211	Q9C0K7
AEYNLEFLKTHSNPG	TMC5	641	Q6UXY8
FIQHQRADSGERPYK	ZNF530	226	Q6P9A1
DANLSRYGIHPAKFA	VWA8	1831	A3KMH1
EHPNKDYLINFEIRS	WDR35	656	Q9P2L0
DNFGKHYTLNSEAPL	SLIT1	1271	O75093
LVAHNGDRYDFPLLQ	TREX1	121	Q9NSU2
GEHQERQNKDPFPYR	SLC14A2	496	Q15849
FAAQGEPKVYNTLRH	SLC25A19	146	Q9HC21
KDVALRYDPISGHNA	TRBV7-1	36	A0A0A6YYK4
ASHIQESRFLYPGKN	GTF2H3	61	Q13889
FQYREAAGPHEAFNK	ZNF449	36	Q6P9G9
ALHAKNAEYNPKRFA	TBPL2	221	Q6SJ96
LRNNPLYHAGAVAFS	UBR5	536	O95071
EPGCERKHYQLNFLL	ZBTB40	231	Q9NUA8
IARKDHPQFLAYIQD	UNC79	991	Q9P2D8
HQQIYPHFADGSNRK	ZNF518B	741	Q9C0D4
PADHFEARGQYVKFL	ADI1	161	Q9BV57
QGLNDRFAGYIEKVH	NEFM	106	P07197