Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.56e-0852074GO:0052871
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.83e-0772074GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.83e-0772074GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.24e-06102074GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.24e-06102074GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.24e-06102074GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.45e-06132074GO:0016713
GeneOntologyMolecularFunctionheme binding

PXDN NOS1 MPO NOX4 CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

3.36e-051542079GO:0020037
GeneOntologyMolecularFunctiontetrapyrrole binding

PXDN NOS1 MPO NOX4 CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

5.50e-051642079GO:0046906
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

NOS1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.59e-05402075GO:0016709
GeneOntologyMolecularFunctionC-acyltransferase activity

ACAA2 HADHA ACSM2A ACSM2B

5.85e-05212074GO:0016408
GeneOntologyMolecularFunctionligase activity

ATP6V1A TTLL9 MCCC2 SLC27A5 TTLL8 PC ACSM2A ATP5F1A ACSM2B

8.69e-051742079GO:0016874
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.01e-04242074GO:0008392
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

1.07e-0422072GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

1.07e-0422072GO:0097259
GeneOntologyMolecularFunctionP-type manganese transporter activity

ATP2C2 ATP2C1

1.07e-0422072GO:0140613
GeneOntologyMolecularFunctionkynurenine-glyoxylate transaminase activity

KYAT3 AADAT

1.07e-0422072GO:0047315
GeneOntologyMolecularFunctionoxidoreductase activity

GPHN ACOX1 DBT HEPH PXDN NOS1 SLC27A5 MPO NOX4 CP CYP4F2 LBR RSBN1 P4HTM PAM CYP4F22 CYP4F3 CYP4F12 HADHA CYP4F11

1.46e-0476620720GO:0016491
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.63e-04272074GO:0008391
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2C2 ATP2C1 ATP2B2

1.70e-04112073GO:0005388
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

DBT GTF3C4 BRCA2 ACAA2 ALAS2 ZDHHC14 ZDHHC23 HADHA ACSM2A ACSM2B

1.98e-0423820710GO:0016747
GeneOntologyMolecularFunctionmonooxygenase activity

NOS1 CYP4F2 PAM CYP4F22 CYP4F3 CYP4F12 CYP4F11

1.98e-041152077GO:0004497
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

NOS1 CYP4F2 RSBN1 P4HTM PAM CYP4F22 CYP4F3 CYP4F12 CYP4F11

1.98e-041942079GO:0016705
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

3.19e-0432072GO:0018858
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4F12 CYP4F11

4.56e-04152073GO:0050544
GeneOntologyMolecularFunctionaromatase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.57e-04352074GO:0070330
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4F12 CYP4F11

5.57e-04162073GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4F12 CYP4F11

5.57e-04162073GO:0050543
GeneOntologyMolecularFunctionkynurenine-oxoglutarate transaminase activity

KYAT3 AADAT

6.33e-0442072GO:0016212
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

6.33e-0442072GO:0102391
GeneOntologyMolecularFunctionfatty acid binding

ACOX1 DBT CYP4F2 CYP4F12 CYP4F11

7.48e-04692075GO:0005504
GeneOntologyMolecularFunctionmonocarboxylic acid binding

ACOX1 DBT CYP4F2 CYP4F12 PC CYP4F11

8.75e-041072076GO:0033293
GeneOntologyMolecularFunctioncarboxylic acid binding

ACOX1 DBT NOS1 CYP4F2 P4HTM PAM CYP4F12 PC CYP4F11

9.01e-042392079GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

ACOX1 DBT NOS1 CYP4F2 P4HTM PAM CYP4F12 PC CYP4F11

1.38e-032542079GO:0043177
GeneOntologyMolecularFunctionmicrofibril binding

POLR2A VWA1

1.56e-0362072GO:0050436
GeneOntologyMolecularFunctionferroxidase activity

HEPH CP

1.56e-0362072GO:0004322
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, oxygen as acceptor

HEPH CP

1.56e-0362072GO:0016724
GeneOntologyMolecularFunctionacetyl-CoA C-acetyltransferase activity

ACAA2 HADHA

1.56e-0362072GO:0003985
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.65e-03492074GO:0016712
GeneOntologyMolecularFunctioniron ion binding

HEPH CYP4F2 P4HTM CYP4F22 CYP4F3 CYP4F12 CYP4F11

1.76e-031662077GO:0005506
GeneOntologyMolecularFunctionligase activity, forming carbon-carbon bonds

MCCC2 PC

2.17e-0372072GO:0016885
GeneOntologyMolecularFunctionC-acetyltransferase activity

ACAA2 HADHA

2.17e-0372072GO:0016453
GeneOntologyMolecularFunctionclathrin light chain binding

CLTCL1 CLTC

2.17e-0372072GO:0032051
GeneOntologyMolecularFunctionacetyl-CoA C-acyltransferase activity

ACAA2 HADHA

2.17e-0372072GO:0003988
GeneOntologyMolecularFunctionfatty acid ligase activity

SLC27A5 ACSM2A ACSM2B

2.39e-03262073GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

SLC27A5 ACSM2A ACSM2B

2.67e-03272073GO:0016405
GeneOntologyMolecularFunctionfatty-acyl-CoA synthase activity

ACSM2A ACSM2B

2.87e-0382072GO:0004321
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F2 CYP4F12 CYP4F11

2.97e-03282073GO:0036041
GeneOntologyMolecularFunctionacyltransferase activity

TRIM75 CUL9 DBT GTF3C4 BRCA2 ACAA2 ALAS2 RNF19A ZDHHC14 ZDHHC23 HECTD2 HADHA LONRF3 ACSM2A RNF133 EPB42 ACSM2B

3.02e-0377520717GO:0016746
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PCDHA9 HMCN2 PTPRR PCDH19 IGSF9 PLXNB3 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.57e-0818720713GO:0007156
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.46e-0762074GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.37e-0772074GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.68e-0782074GO:0036100
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PCDHA9 HMCN2 PTPRR PCDH19 IGSF9 PLXNB3 PCDHGC5 PCDHGA11 ICAM1 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1 ATP2C1

6.79e-0731320715GO:0098742
GeneOntologyBiologicalProcessorganic acid catabolic process

ACOX1 MCCC2 NUDT8 DBT ACAA2 ECI2 NOS1 CYP4F2 KYAT3 CYP4F3 CYP4F12 HADHA AADAT CYP4F11

6.93e-0727220714GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

ACOX1 MCCC2 NUDT8 DBT ACAA2 ECI2 NOS1 CYP4F2 KYAT3 CYP4F3 CYP4F12 HADHA AADAT CYP4F11

6.93e-0727220714GO:0046395
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

9.96e-0732073GO:0042361
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

NUDT8 SLC27A5 CYP4F2 PAM CYP4F3 CYP4F12 ACSM2A CYP4F11

1.70e-06822078GO:1901568
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

NUDT8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.22e-06222075GO:1901569
GeneOntologyBiologicalProcessfatty acid catabolic process

ACOX1 NUDT8 ACAA2 ECI2 CYP4F2 CYP4F3 CYP4F12 HADHA CYP4F11

2.62e-061162079GO:0009062
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.08e-06112074GO:1901523
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

3.96e-0642073GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

3.96e-0642073GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12 CYP4F11

3.96e-0642073GO:0042377
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

3.96e-0642073GO:0009233
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.58e-06122074GO:0042758
GeneOntologyBiologicalProcessmonocarboxylic acid catabolic process

ACOX1 NUDT8 ACAA2 ECI2 CYP4F2 CYP4F3 CYP4F12 HADHA CYP4F11

1.62e-051452079GO:0072329
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F12 CYP4F11

1.95e-0562073GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F12 CYP4F11

1.95e-0562073GO:0062232
GeneOntologyBiologicalProcesssmall molecule catabolic process

ACOX1 MCCC2 NUDT8 DBT ACAA2 ECI2 NOS1 CYP4F2 KYAT3 CYP4F3 CYP4F12 HADHA AADAT FUT4 CYP4F11

2.45e-0542120715GO:0044282
GeneOntologyBiologicalProcessketone catabolic process

CYP4F2 KYAT3 CYP4F12 CYP4F11

5.16e-05212074GO:0042182
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase III promoter

BDP1 GTF3C4 BRF1

5.38e-0582073GO:0006384
GeneOntologyBiologicalProcessoxoacid metabolic process

ACOX1 MCCC2 NUDT8 DBT ACAA2 ECI2 NOS1 SLC27A5 MPO NOX4 CYP4F2 SEPHS1 P4HTM PAM CYP4F22 KYAT3 CYP4F3 CYP4F12 HADHA AADAT PC ACSM2A CYP4F11 ADPGK ACSM2B

6.29e-05105820725GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

ACOX1 MCCC2 NUDT8 DBT ACAA2 ECI2 NOS1 SLC27A5 MPO NOX4 CYP4F2 SEPHS1 P4HTM PAM CYP4F22 KYAT3 CYP4F3 CYP4F12 HADHA AADAT PC ACSM2A CYP4F11 ADPGK ACSM2B

6.89e-05106420725GO:0006082
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

ACOX1 MCCC2 NUDT8 DBT ACAA2 ECI2 NOS1 SLC27A5 NOX4 CYP4F2 SEPHS1 P4HTM PAM CYP4F22 KYAT3 CYP4F3 CYP4F12 HADHA AADAT PC ACSM2A CYP4F11 ADPGK ACSM2B

1.19e-04103520724GO:0019752
GeneOntologyBiologicalProcesstransition metal ion transport

HEPH SLC39A13 ATP2C2 CLTC NOS1 CP ATP2C1

1.46e-041132077GO:0000041
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F2 CYP4F12 CYP4F11

1.55e-04112073GO:0042373
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

2.05e-04122073GO:0042363
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4F2 CYP4F12 CYP4F11

3.34e-04142073GO:0097267
GeneOntologyBiologicalProcessvery long-chain fatty acid metabolic process

ACOX1 SLC27A5 CYP4F2 CYP4F12

4.04e-04352074GO:0000038
GeneOntologyCellularComponentpostsynaptic specialization, intracellular component

GPHN DLG3 NOS1 LCK TANC1 GRIP2

1.94e-05562086GO:0099091
GeneOntologyCellularComponentRNA polymerase III transcription regulator complex

BDP1 GTF3C4 BRF1

7.80e-0592083GO:0090576
GeneOntologyCellularComponenttranscription factor TFIIIB complex

BDP1 BRF1

2.94e-0432082GO:0000126
DomainCadherin_tail

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.83e-09372078PF15974
DomainCadherin_CBD

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.83e-09372078IPR031904
DomainCadherin_2

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

3.96e-08652079PF08266
DomainCadherin_N

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

3.96e-08652079IPR013164
DomainCadherin_CS

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

3.47e-061092079IPR020894
DomainCADHERIN_1

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

4.68e-061132079PS00232
DomainCadherin

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

4.68e-061132079PF00028
DomainCADHERIN_2

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.03e-061142079PS50268
Domain-

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.03e-0611420792.60.40.60
DomainDUF4195

ZNF280A ZNF280D ZNF280C

5.32e-0642073IPR025243
DomainDUF4195

ZNF280A ZNF280D ZNF280C

5.32e-0642073PF13836
DomainCA

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.41e-061152079SM00112
DomainCadherin-like

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.81e-061162079IPR015919
DomainCadherin

PCDHA9 PCDH19 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

6.68e-061182079IPR002126
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

1.22e-0422072IPR022365
DomainClathrin-link

CLTCL1 CLTC

1.22e-0422072PF09268
Domain-

CLTCL1 CLTC

1.22e-04220722.130.10.110
DomainClathrin_heavy_chain

CLTCL1 CLTC

1.22e-0422072IPR016341
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

1.22e-0422072IPR001473
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

1.22e-0422072IPR016025
DomainClathrin_propel

CLTCL1 CLTC

1.22e-0422072PF01394
DomainP-type_ATPase_IIA_PMR1

ATP2C2 ATP2C1

1.22e-0422072IPR006413
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

1.22e-0422072IPR015348
DomainCyt_P450_E_grp-I

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

1.36e-04452075IPR002401
DomainPDZ

MPDZ PARD6B AHNAK DLG3 NOS1 PRX GRIP2 PDZD2

1.79e-041412078PF00595
DomainAMP_BINDING

SLC27A5 DIP2C ACSM2A ACSM2B

2.44e-04282074PS00455
DomainPDZ

MPDZ PARD6B AHNAK DLG3 NOS1 PRX GRIP2 PDZD2

2.49e-041482078SM00228
Domain-

MPDZ PARD6B AHNAK DLG3 NOS1 PRX GRIP2 PDZD2

2.73e-0415020782.30.42.10
DomainPDZ

MPDZ PARD6B AHNAK DLG3 NOS1 PRX GRIP2 PDZD2

2.85e-041512078PS50106
DomainCyt_P450_CS

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

2.97e-04532075IPR017972
DomainPDZ

MPDZ PARD6B AHNAK DLG3 NOS1 PRX GRIP2 PDZD2

2.98e-041522078IPR001478
DomainVWFA

ITGB8 HMCN2 VWA2 COL7A1 VWA1 CPNE5

3.00e-04822076PS50234
DomainAMP-binding

SLC27A5 DIP2C ACSM2A ACSM2B

3.20e-04302074PF00501
DomainAMP-dep_Synth/Lig

SLC27A5 DIP2C ACSM2A ACSM2B

3.20e-04302074IPR000873
DomainVWA

ITGB8 HMCN2 VWA2 COL7A1 VWA1 CPNE5

3.42e-04842076SM00327
DomainClathrin_H-chain_linker

CLTCL1 CLTC

3.64e-0432072IPR012331
DomainMULTICOPPER_OXIDASE2

HEPH CP

3.64e-0432072PS00080
DomainCu-oxidase

HEPH CP

3.64e-0432072PF00394
DomainCLH

CLTCL1 CLTC

3.64e-0432072SM00299
DomainCu-oxidase

HEPH CP

3.64e-0432072IPR001117
DomainCYTOCHROME_P450

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

4.18e-04572075PS00086
Domain-

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

4.53e-045820751.10.630.10
Domainp450

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

4.53e-04582075PF00067
DomainCyt_P450

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

5.31e-04602075IPR001128
DomainATPase_P-typ_TM_dom

ATP2C2 ATP2C1 ATP2B2

6.75e-04162073IPR023298
Domain-

ATP2C2 ATP2C1 ATP2B2

6.75e-041620731.20.1110.10
DomainCu-oxidase_2

HEPH CP

7.23e-0442072IPR011706
DomainCu-oxidase_2

HEPH CP

7.23e-0442072PF07731
DomainATPase_P-typ_cation-transptr_C

ATP2C2 ATP2C1 ATP2B2

8.14e-04172073IPR006068
DomainCation_ATPase_C

ATP2C2 ATP2C1 ATP2B2

8.14e-04172073PF00689
DomainAminotran_1_2

ALAS2 KYAT3 AADAT

8.14e-04172073PF00155
DomainAminotransferase_I/II

ALAS2 KYAT3 AADAT

8.14e-04172073IPR004839
DomainAMP-bd_C

SLC27A5 ACSM2A ACSM2B

8.14e-04172073IPR025110
DomainAMP-binding_C

SLC27A5 ACSM2A ACSM2B

8.14e-04172073PF13193
DomainVWF_A

ITGB8 HMCN2 VWA2 COL7A1 VWA1 CPNE5

8.21e-04992076IPR002035
DomainCation_ATPase_N

ATP2C2 ATP2C1 ATP2B2

9.68e-04182073PF00690
DomainCation_ATPase_N

ATP2C2 ATP2C1 ATP2B2

9.68e-04182073SM00831
DomainATPase_P-typ_cation-transptr_N

ATP2C2 ATP2C1 ATP2B2

1.14e-03192073IPR004014
DomainATP_synth_asu_C

ATP6V1A ATP5F1A

1.20e-0352072IPR000793
DomainATP-synt_ab_N

ATP6V1A ATP5F1A

1.20e-0352072PF02874
DomainCu-oxidase_3

HEPH CP

1.20e-0352072IPR011707
DomainATPase_F1/V1/A1_a/bsu_N

ATP6V1A ATP5F1A

1.20e-0352072IPR004100
DomainMULTICOPPER_OXIDASE1

HEPH CP

1.20e-0352072PS00079
DomainCu_oxidase_CS

HEPH CP

1.20e-0352072IPR033138
DomainATPase_a/bsu_AS

ATP6V1A ATP5F1A

1.20e-0352072IPR020003
DomainATP-synt_ab_C

ATP6V1A ATP5F1A

1.20e-0352072PF00306
DomainATP-synt_ab

ATP6V1A ATP5F1A

1.20e-0352072PF00006
DomainATPASE_ALPHA_BETA

ATP6V1A ATP5F1A

1.20e-0352072PS00152
DomainCu-oxidase_3

HEPH CP

1.20e-0352072PF07732
Domain-

ITGB8 VWA2 COL7A1 VWA1 CPNE5

1.38e-037420753.40.50.410
DomainARM-type_fold

MON2 CAND1 CLTCL1 CUL9 NCDN CLTC ULK4 NOC4L PDS5A FMNL1 EIF4G3

1.46e-0333920711IPR016024
Domain-

MCCC2 ECI2 HADHA

1.54e-032120733.90.226.10
DomainClpP/crotonase-like_dom

MCCC2 ECI2 HADHA

1.54e-03212073IPR029045
DomainATPase_F1/V1/A1_a/bsu_nucl-bd

ATP6V1A ATP5F1A

1.78e-0362072IPR000194
DomainCu_oxidase_Cu_BS

HEPH CP

1.78e-0362072IPR002355
DomainPEROXIDASE_1

PXDN MPO

1.78e-0362072PS00435
DomainHAD-like_dom

MDP1 ATP2C2 UBLCP1 ATP2C1 ATP2B2

1.85e-03792075IPR023214
Domainfn3

CMYA5 IGSF9 MPL COL7A1 TNC VWA1 IL2RG

2.23e-031622077PF00041
DomainClathrin

CLTCL1 CLTC

2.47e-0372072PF00637
DomainCHCR

CLTCL1 CLTC

2.47e-0372072PS50236
DomainAMP-binding_CS

SLC27A5 ACSM2A ACSM2B

2.89e-03262073IPR020845
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

8.60e-08121475M27129
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

8.60e-08121475MM14845
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

3.18e-07151475M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

8.85e-07181475MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

8.85e-07181475MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

5.17e-06251475MM14858
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F22 CYP4F3 CYP4F11

5.26e-06121474M27128
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.05e-05141474MM15842
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

ACOX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.16e-05331475MM15918
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

ACOX1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.16e-05331475MM15963
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F22 CYP4F3 CYP4F11

5.92e-05211474M27137
PathwayREACTOME_FATTY_ACID_METABOLISM

ACOX1 ACAA2 ECI2 CYP4F2 CYP4F22 CYP4F3 CYP4F12 HADHA CYP4F11

7.24e-051701479MM15573
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F2 CYP4F12 CYP4F11

1.72e-04111473MM14863
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

4.28e-04611475MM14861
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

4.62e-04621475M39653
PathwayREACTOME_FATTY_ACID_METABOLISM

ACOX1 ACAA2 ECI2 CYP4F2 CYP4F22 CYP4F3 HADHA CYP4F11

5.14e-041761478M27854
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

5.35e-04641475M5650
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

4.50e-1228211815347688
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

2.22e-1015211615640798
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.44e-1017211629911975
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

8.11e-1018211615570159
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

8.11e-1018211610662547
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.32e-094211418065749
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

2.06e-0957211832633719
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

5.71e-0924211624698270
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

8.69e-0968211811230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

1.38e-0872211810380929
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

PCDHA9 KMT2B CUL9 BRCA2 EHMT2 MOS PCDHA8 PCDHA6 CYP4F2 PCDHA3 PCDHA1 PRX GRIP2 IL2RG

1.68e-083292111417474147
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

1.72e-0874211810817752
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 CLTCL1 KMT2B KIF26A CUL9 ZFPM1 AHDC1 MYORG WIZ AHNAK ULK4 CHPF RHOF ZNF687 ENGASE ZNF628 POLR2A CFAP43 LRRK1 NCOR2 DIP2C HMGXB3 TANC1 ARRDC2 PC

1.84e-0811052112535748872
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.96e-08621149068972
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

2.36e-0877211810835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

3.20e-0880211810716726
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHA9 PCDHGC5 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

6.33e-0858211730377227
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MON2 DDN CUL9 NCDN PXDN FBXO28 PCDH19 CLTC DLG3 CLEC16A PLXNB3 RSBN1 TRAK2 PDZD2

2.30e-074072111412693553
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

KMT2B ZNF280D RUSC1 MCCC2 GTF3C4 WIZ ALMS1 BRCA2 EHMT2 AHNAK ZNF687 L3MBTL2 NCOR2 PC

3.17e-074182111434709266
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

GABRE BDP1 ATP6V1A CAND1 MCCC2 AHDC1 NCDN PXDN PTPRR IGSF9 TRMT13 CLEC16A B3GNTL1 RASA1 SGTA ZDHHC14 CHD9 UBLCP1 NCOR2 ATP2C1 DIP2C KYAT3 TANC1 AADAT EIF4G3 CYP4F11 PDZD2

4.17e-0714892112728611215
Pubmed

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.

PCDHA9 PCDHA13 PCDHA8 PCDHA6

4.20e-071121149655502
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MON2 TPP2 SPTBN2 DBT MTMR11 WIZ PTPRR AHNAK CLTC DDX54 PHLPP1 NOC4L ADGRL2 POLR2A ZNF280C CCDC61 UBLCP1 NCOR2 TANC1 HADHA PC ATP5F1A

5.02e-0710492112227880917
Pubmed

Proteins of the CNR family are multiple receptors for Reelin.

PCDHA9 PCDHA13 PCDHA8 PCDHA6

6.27e-0712211410612399
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

8.77e-074211322665481
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F12 CYP4F11

8.77e-074211311185557
Pubmed

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

ATP6V1A ACOX1 MCCC2 NUDT8 DBT CLTC ACAA2 ALAS2 MPO NTHL1 HADHA AADAT POLG2 PC ATP5F1A

1.32e-065422111514651853
Pubmed

Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.

ACOX1 MCCC2 DBT ACAA2 HADHA ACSM2A ATP5F1A ACSM2B

1.55e-06132211822496890
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

2.18e-065211322969154
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F12 CYP4F11

2.18e-065211321466787
Pubmed

Defining the membrane proteome of NK cells.

CAND1 CLTCL1 ACOX1 TUBGCP4 NCDN AHNAK CLTC DDX54 ECI2 FMNL1 PIGO NPM1 ICAM1 LBR NBAS NCOR2 ATP2C1 RASAL3 PAM IL2RG ADPGK ATP5F1A

2.91e-0611682112219946888
Pubmed

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.

PCDHA9 CEP120 PCDHA13 CP PCDHA8 PCDHA6 PCDHA3 PCDHA1 KCNH5

3.04e-06193211922589738
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PCDHA9 KMT2B SPTBN2 ALMS1 CLEC16A CHD9 PDZD2

3.53e-0610421179205841
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MON2 CUL9 DBT WIZ HMCN2 ALMS1 EHMT2 PCDH19 ADGRL2 ZNF687 NPM1 POLR2A CHD9 LBR RSBN1 NCOR2 ATP2C1 RASAL3 TANC1 SIGLEC1 LONRF3

5.02e-0611162112131753913
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ATP6V1A CAND1 MCCC2 WIZ EHMT2 AHNAK CLTC PDS5A DLG3 ADGRL2 CLEC16A NPM1 LBR DENND6A EIF4G3 PC ATP5F1A

6.09e-067772111735844135
Pubmed

Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.

ZNF280D AHDC1 WIZ EHMT2 L3MBTL2 ZNF280C

6.10e-0674211629795351
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

6.60e-0675211615372022
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F2 CYP4F12 CYP4F11

7.57e-067211322160543
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

PCDHA9 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

8.63e-06119211728625976
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

GPHN MCCC2 DBT SLC39A13 MDP1 CLCN6 AHNAK CLTC OSBPL11 ACAA2 PIGO MOCS1 NPM1 TMEM53 CP LBR ALG1L2 RSBN1 MRM3 NCOR2 PAM HADHA ADPGK ATP5F1A

9.10e-0614512112430550785
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

GGNBP2 SPTBN2 CUL9 EXOSC5 DDX54 CFAP70 MPO L3MBTL2 CFAP43 LCK AGO1 HADHA LONRF3

1.21e-054962111331343991
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

GGNBP2 CAND1 KMT2B MPDZ EXOSC5 AHDC1 PARD6B WIZ PXDN EHMT2 FBXO28 NOC4L PDS5A DLG3 ZNF687 RHOD NTHL1 POLR2A DGKZ RSBN1 MRM3 TANC1 EIF4G3 ATP5F1A

1.52e-0514972112431527615
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

GPHN KMT2B SPTBN2 MPDZ MCCC2 GTF3C4 WIZ ALMS1 AHNAK CLTC OSBPL11 POLR2A PC

3.47e-055492111338280479
Pubmed

Secretory pathway Ca2+ -ATPases promote in vitro microcalcifications in breast cancer cells.

ATP2C2 ATP2C1

3.66e-052211228618103
Pubmed

Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis.

HEPH CP

3.66e-052211230060949
Pubmed

Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionine.

KYAT3 AADAT

3.66e-052211225231977
Pubmed

NIDD, a novel DHHC-containing protein, targets neuronal nitric-oxide synthase (nNOS) to the synaptic membrane through a PDZ-dependent interaction and regulates nNOS activity.

NOS1 ZDHHC23

3.66e-052211215105416
Pubmed

The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments.

FMN1 FMNL1

3.66e-052211214990563
Pubmed

Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.

HEPH CP

3.66e-052211222342521
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

3.66e-052211219634011
Pubmed

The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration.

HEPH CP

3.66e-052211221051716
Pubmed

Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells.

POLR2A AGO1

3.66e-052211216936726
Pubmed

Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2.

FMN1 FMNL1

3.66e-052211216480715
Pubmed

Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone.

HEPH CP

3.66e-052211226303407
Pubmed

Ablation of hephaestin and ceruloplasmin results in iron accumulation in adipocytes and type 2 diabetes.

HEPH CP

3.66e-052211229355933
Pubmed

Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney.

HEPH CP

3.66e-052211227991585
Pubmed

Human gut-microbiome-derived propionate coordinates proteasomal degradation via HECTD2 upregulation to target EHMT2 in colorectal cancer.

EHMT2 HECTD2

3.66e-052211234972816
Pubmed

Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.

ATP2C2 ATP2C1

3.66e-052211216332677
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

3.66e-05221128733129
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

3.66e-052211216521160
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

3.66e-052211224138531
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

3.66e-052211218662666
Pubmed

Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.

HEPH CP

3.66e-052211218326691
Pubmed

Hephaestin and ceruloplasmin play distinct but interrelated roles in iron homeostasis in mouse brain.

HEPH CP

3.66e-052211225788583
Pubmed

Expression and physiological function of CYP4F subfamily in human eosinophils.

CYP4F3 CYP4F12

3.66e-052211217980168
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

3.66e-05221128026587
Pubmed

Tacrolimus increases Nox4 expression in human renal fibroblasts and induces fibrosis-related genes by aberrant TGF-beta receptor signalling.

NOX4 TGFBR1

3.66e-052211224816588
Pubmed

BRCA2 Regulates Transcription Elongation by RNA Polymerase II to Prevent R-Loop Accumulation.

BRCA2 POLR2A

3.66e-052211229386125
Pubmed

Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration.

HEPH CP

3.66e-052211215365174
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

3.66e-052211229097553
Pubmed

The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities.

ACAA2 HADHA

3.66e-052211225478839
Pubmed

Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?

MPO CP

3.66e-05221129097926
Pubmed

Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux.

HEPH CP

3.66e-052211229883959
Pubmed

Intron-less processed Pcdhalpha genes in the central nervous system.

PCDHA8 PCDHA6

3.66e-052211214697259
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

3.66e-052211220065094
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

3.66e-052211215364545
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

3.66e-052211229948332
Pubmed

Ceruloplasmin is an endogenous inhibitor of myeloperoxidase.

MPO CP

3.66e-052211223306200
Pubmed

Ceruloplasmin and myeloperoxidase in complex affect the enzymatic properties of each other.

MPO CP

3.66e-052211219031316
Pubmed

Identification of intrinsic primary afferent neurons in mouse jejunum.

NOS1 POLR2A

3.66e-052211232986284
Pubmed

Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture.

HEPH CP

3.66e-052211217065470
Pubmed

Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes.

HEPH CP

3.66e-052211231263155
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

AHDC1 GTF3C4 PXDN AHNAK CLTC ADGRL2 COL5A2 L3MBTL2 RNF19A HMGXB3

3.93e-053322111037433992
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

GPHN TPP2 ATP6V1A CAND1 SPTBN2 NCDN CLTC DLG3 NPM1 ATP2B2 ATP5F1A

3.96e-054032111130562941
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BDP1 KIF26A NWD2 DLG3 PLXNB3 GRIP2

4.07e-05103211610574462
Pubmed

Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.

MCCC2 LBR HADHA PC ATP5F1A

5.58e-0567211530669930
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

GPHN CAND1 SPTBN2 DDN NCDN AHNAK CLTC DLG3 DGKZ

6.00e-05281211928706196
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

6.89e-0570211515128046
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

ATP6V1A CAND1 WIZ BRCA2 CLTC DDX54 ZNF687 NPM1 PC ATP5F1A

7.19e-053572111037059091
Pubmed

Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants.

CP NCOR2 ZDHHC23 TANC1 TRAK2 ATP2B2

8.30e-05117211612107410
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

GPHN TUBGCP4 GTF3C4 NCDN PARD6B CEP120 EHMT2 FBXO28 AHNAK CLTC PDS5A MPO ZWILCH L3MBTL2 POLR2A ICAM1 LCK NBAS HADHA

8.78e-0511552111920360068
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

EXOSC5 DBT WIZ FBXO28 NOC4L FMNL1 POLR2A RSBN1 EIF4G3 PC

9.65e-053702111022922362
Pubmed

Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.

CLTCL1 CLTC

1.09e-043211219509056
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

1.09e-043211215145985
Pubmed

The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining.

KYAT3 AADAT

1.09e-043211228706436
Pubmed

Peroxidasin and eosinophil peroxidase, but not myeloperoxidase, contribute to renal fibrosis in the murine unilateral ureteral obstruction model.

PXDN MPO

1.09e-043211230565999
Pubmed

AMACO is a component of the basement membrane-associated Fraser complex.

VWA2 COL7A1

1.09e-043211224232570
Pubmed

TGF-β directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury.

NOX4 TGFBR1

1.09e-043211224324142
Pubmed

Ferroportin and exocytoplasmic ferroxidase activity are required for brain microvascular endothelial cell iron efflux.

HEPH CP

1.09e-043211223640881
Pubmed

Ago1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cells.

POLR2A AGO1

1.09e-043211224086155
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

AHNAK PRX

1.09e-043211221940993
InteractionPCDHA10 interactions

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 VWA1

7.31e-08222086int:PCDHA10
InteractionEPHB4 interactions

GABRE KLRG2 NRROS DDX54 RHOF RHOD PCDHA8 LCK NRSN1 ADPGK

2.89e-0614620810int:EPHB4
Cytoband5q31

PCDHA9 SLC4A9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

3.56e-0911521195q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHA9 PROB1 SLC4A9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

1.41e-0629821110chr5q31
GeneFamilyClustered protocadherins

PCDHA9 PCDHGC5 PCDHGA11 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

2.59e-0864136820
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4F22 CYP4F3 CYP4F12 CYP4F11

6.99e-063613651003
GeneFamilyPDZ domain containing

MPDZ PARD6B AHNAK DLG3 NOS1 PRX GRIP2 PDZD2

1.97e-0515213681220
GeneFamilyATPases Ca2+ transporting

ATP2C2 ATP2C1 ATP2B2

3.38e-05913631209
GeneFamilyFibronectin type III domain containing

CMYA5 IGSF9 MPL COL7A1 TNC VWA1 IL2RG

2.09e-041601367555
GeneFamilyAcyl-CoA synthetase family

SLC27A5 ACSM2A ACSM2B

9.54e-0426136340
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA1 RASAL3

2.43e-03101362830
CoexpressionFERNANDEZ_BOUND_BY_MYC

ACOX1 INSM1 CLCN6 BRCA2 MPO NTHL1 ICAM1 LBR TGFBR1 EPB42

2.26e-0618121110M3456
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|lymph-node_spleen / Manually curated celltypes from each tissue

MPDZ NUDT8 BRCA2 VSIG10L MPO ENGASE NPR3 B3GNTL1 ATP2C1 BRF1

1.86e-08183211106c55fd737ed31f5b1aa41dc4dba7240521c19022
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GABRE NUDT8 PXDN CHPF TNC CP VWA1 ERN2 PAM TNS4

3.73e-0819721110a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2B MPDZ DDX54 ALAS2 FMNL1 HTR2B ZNF280C PCDHA8 SLC16A8

8.86e-081632119953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

ALAS2 ZNF687 COL5A2 NTHL1 PCDHA8 PCDHA3 PCDHA1 KYAT3

9.47e-071592118b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

CMYA5 TTC34 CFAP221 MPL CP CFAP43 ST6GALNAC2 CYP4F11

1.64e-06171211874be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPHN NOX4 CYP4F2 CYP4F3 PC ACSM2A ACSM2B PDZD2

2.71e-061832118facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CMYA5 MYORG TNC LRRK1 GRIP2 TNS4 AADAT MX1

3.18e-061872118a6a112689d1c9049f57935ad9d2f4955538427de
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PXDN PHLPP1 ADGRL2 ZDHHC14 NOX4 PRX TANC1 TMEM26

3.58e-0619021180a351609a72fd638c84b2435782e312ee6a33aac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPHN CMYA5 ITGB8 PARD6B NOX4 DIP2C ACSM2A ACSM2B

4.18e-0619421187002937e8903e037332a215d00fbc7c7843b33f2
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GABRE KMT2B TTLL9 AHDC1 PHLPP1 TRAK2 EPB42

7.53e-061502117b6f1fc62d08199fed6156c7cd32f66d9926531b5
ToppCellStriatum-Neuronal-Inhibitory|Striatum / BrainAtlas - Mouse McCarroll V32

PCDHA9 TCERG1L FMN1 NOS1 PCDHA3 NRSN1 EIF4G3

1.01e-051572117c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCelldroplet-Liver-LIVER_NPC-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK ALAS2 RHOF FMNL1 LCK RASAL3 SYTL3

1.10e-051592117997963d879e5819683793cddf5e1acff1b81a1b8
ToppCelldroplet-Liver-LIVER_NPC|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK ALAS2 RHOF FMNL1 LCK RASAL3 SYTL3

1.10e-051592117e4eaa88772835d6b78e1a18a0cec52de51e80339
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACOX1 ALMS1 ATP2C2 CLTC NOC4L SGTA ST6GALNAC2

1.58e-05168211708f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCCC2 ITGB8 VWA2 CP ADAMTS8 KYAT3 AADAT

1.64e-051692117f00741203efa0b948db7223ee8c19bdd0918258a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLRG2 ITGB8 AHNAK IGSF9 NPR3 CFAP43 LBR

1.64e-0516921178f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PXDN PCDH19 ADGRL2 COL5A2 COL7A1 CP TANC1

1.64e-051692117c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MTMR11 CEP120 VSIG10L ADGRL2 PRX TGFBR1 TNS4

1.70e-051702117a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MTMR11 CEP120 VSIG10L ADGRL2 PRX TGFBR1 TNS4

1.70e-051702117b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TCERG1L CMYA5 NWD2 COL5A2 LRRK1 TMEM26 KCNH5

1.70e-051702117985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRE RHOF TNC LCK IKZF4 RASAL3 IL2RG

1.83e-051722117b440184f2d98d2f2d59566795f44fb79c0647ca4
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TCERG1L PXDN ADGRL2 COL5A2 HTR2B DIP2C GRIP2

1.90e-05173211726e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

TCERG1L PXDN ADGRL2 COL5A2 HTR2B DIP2C GRIP2

1.90e-05173211775e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A HEPH COL7A1 NPR3 CCDC61 HECTD2 PDZD2

2.13e-05176211727e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRE CMYA5 ITGB8 ATP2C2 ERN2 CYP4F3 TANC1

2.37e-0517921176e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLRG2 ITGB8 CFAP221 ZDHHC14 CFAP43 LBR HYDIN

2.55e-0518121176a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HEPH HMCN2 AHNAK NPR3 HTR2B TNC ADAMTS8

2.55e-051812117beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLRG2 ITGB8 PARD6B PXDN CFAP221 ATP2C2 PDZD2

2.55e-0518121179d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLRG2 ITGB8 PARD6B PXDN CFAP221 ATP2C2 PDZD2

2.64e-051822117eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCDN WIZ CHPF CTU1 PIGO TANC1 SLC26A11

2.83e-051842117a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGB8 NWD2 PXDN ADGRL2 COL5A2 CPNE5 ZDHHC23

2.83e-051842117ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP221 ZDHHC14 CFAP43 SYTL3 DIP2C HYDIN PDZD2

3.03e-051862117f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TCERG1L NWD2 CFAP221 ADGRL2 COL5A2 LRRK1 KCNH5

3.03e-051862117bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPTBN2 CFAP221 CPNE5 DIP2C MX1 KCNH5

3.06e-051262116518a6e4919981b556ce6b451a91270dba976bc75
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP221 ZDHHC14 CFAP43 SYTL3 DIP2C HYDIN PDZD2

3.13e-051872117c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CLTCL1 CMYA5 ADGRL2 CPNE5 PAM TANC1 GRIP2

3.24e-0518821176d249fe92d51a19da19ec14bb2262d394255d577
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGB8 CFAP221 VWA2 COL7A1 ST6GALNAC2 NRSN1 HYDIN

3.35e-051892117aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGB8 CFAP221 VWA2 COL7A1 ST6GALNAC2 NRSN1 HYDIN

3.35e-0518921178977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRE ITGB8 CP ERN2 CYP4F3 CYP4F12 TRAK2

3.47e-0519021176ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCellhuman_hepatoblastoma-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

GABRE PXDN ADGRL2 NOX4 CPNE5 PAM PDZD2

3.47e-0519021178d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

CFAP95 TTLL9 CFAP221 ATP2C2 CP CFAP43 HYDIN

3.59e-051912117ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PXDN ADGRL2 ZDHHC14 NOX4 PRX TANC1 TMEM26

3.59e-051912117f229abf69a1217194f74b0502486907e07dba989
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

CFAP95 TTLL9 CFAP221 ATP2C2 CP CFAP43 HYDIN

3.59e-0519121176228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

CFAP95 MPDZ PARD6B CFAP221 CFAP43 TANC1 HYDIN

3.71e-0519221170644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellhuman_hepatoblastoma-Endothelial_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

GABRE PXDN ADGRL2 NOX4 CPNE5 PAM PDZD2

3.71e-051922117e09f609fed033a25baacaf4a07bbbae1076da366
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ZFPM1 ALAS2 RNF19A CYP4F12 TRAK2 ARRDC2 EPB42

3.83e-051932117be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PXDN PCDH19 ADGRL2 COL5A2 CP PAM TANC1

4.23e-0519621172ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 MPDZ CFAP221 ULK4 CFAP70 CFAP43 HYDIN

4.37e-05197211774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellsevere_COVID-19-CD8+_Tem|severe_COVID-19 / disease group, cell group and cell class (v2)

RHOF NPM1 RNF19A LCK RASAL3 SYTL3 IL2RG

4.51e-05198211769d49f37cf5095e65c71cddc6d43748322ff19a3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte|GW10 / Sample Type, Dataset, Time_group, and Cell type.

GABRE MYORG DDX54 SLC27A5 TNC ARRDC2 TMEM26

4.80e-05200211798a994692440cb4f505b050276f0c8022c814a21
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ITGB8 PXDN NPR3 TNC NOX4 ACSM2A ACSM2B

4.80e-052002117105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial|GW10 / Sample Type, Dataset, Time_group, and Cell type.

GABRE MYORG DDX54 SLC27A5 TNC ARRDC2 TMEM26

4.80e-052002117ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCellASK452-Epithelial-Type_2|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

VWA2 B3GNTL1 PRX IKZF4 MRM3

5.23e-05852115523a532e91aa271faab67d0256919b67af2bd7d8
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

GABRE TTLL9 AHDC1 PHLPP1 TRAK2 EPB42

6.45e-05144211657d2846ec26d4490ec11c171af447b17a729437e
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX1 ALAS2 SLC27A5 NOX4 CP AADAT

7.23e-05147211600619115b9a1ec2b967c2992043b41974ece63c4
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GABRE MYORG B3GNTL1 WDR97 ARRDC2 PDZD2

7.51e-0514821161d9fa6b2ee9feaed39c63d44e638b5c0942d947c
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

PCDH19 SLC4A9 MOCS1 COL5A2 ADAMTS8 TMEM26

7.51e-05148211681a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellAdult-Immune-enucleated_erythrocyte-D175|Adult / Lineage, Cell type, age group and donor

SPTBN2 HMCN2 NOC4L COL7A1 NPR3 CPNE5

8.70e-051522116530d5427d8617dcb223d807b73abee0ef89285f3
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL9 TTC34 CFAP221 ATP2C2 CFAP43 HYDIN

9.34e-0515421164e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL9 TTC34 CFAP221 ATP2C2 CFAP43 HYDIN

9.34e-0515421167556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 HEPH CHPF LCK PRX ATP2B2

9.68e-051552116c58a5fb8d853f12204e961d633e83452eb12a659
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 HEPH CHPF LCK PRX ATP2B2

9.68e-0515521169cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

MPDZ CFAP221 ATP2C2 CFAP70 CFAP43 SYTL3

1.00e-04156211610d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CEP120 ALMS1 BRCA2 CFAP70 ZDHHC23 HYDIN

1.04e-041572116410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGSF9 FMNL1 COL5A2 TGFBR1 ZDHHC23 KCNH5

1.08e-041582116c8af8964a140acb2987e3b4906d72c546108d229
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KLRG2 RUSC1 MTMR11 CHPF COL7A1 ATP2B2

1.11e-041592116c8b42ebc25ebcc450832096fbffaa5c5f5fe88e7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KLRG2 RUSC1 MTMR11 CHPF COL7A1 ATP2B2

1.11e-0415921169f6607e395bcca9cb1c83199bdbbaaa62a93938d
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZFPM1 RHOF LCK RASAL3 SYTL3 IL2RG

1.32e-041642116d4d08353c7322f97ea07dd583b08661d635fff20
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZFPM1 RHOF LCK RASAL3 SYTL3 IL2RG

1.36e-04165211688745bf7ecb0f7fc93077cea20171d40535dd56b
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCCC2 VWA2 CP ADAMTS8 KYAT3 AADAT

1.46e-041672116ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCCC2 ITGB8 VWA2 VWA1 KYAT3 AADAT

1.46e-04167211640d102e01ccbc7262d00fafd59ca5234909009cb
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|356C / Donor, Lineage, Cell class and subclass (all cells)

TCERG1L RNF19A LCK SYTL3 CYP4F22 IL2RG

1.50e-0416821169d6ca10c272aea28082c09d469940f7232f6461c
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)|Hippocampus / BrainAtlas - Mouse McCarroll V32

DDN NCDN DNAJB5 NPR3 ZDHHC23 TANC1

1.50e-0416821166db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNB3 ENGASE ZDHHC14 SIGLEC1 TNS4 TMEM26

1.50e-04168211604e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOF LCK IKZF4 RASAL3 SYTL3 IL2RG

1.50e-041682116dc1143bd8db70c490167d73a525fd9b783eba960
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOF LCK IKZF4 RASAL3 SYTL3 IL2RG

1.50e-041682116a75d63ae8ad64b5560853775f6df398feb314ce8
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 LCK RASAL3 SYTL3 IL2RG ATP2B2

1.50e-0416821161254c66f0cd53ef3b913933c0b0648d091da07e9
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVPL PARD6B WIZ P4HTM HECTD2 HMGXB3

1.50e-041682116b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 CFAP221 ULK4 CFAP70 CFAP43 HYDIN

1.55e-041692116fba841664939c771881ba97f14ef1df6635c04ff
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK ALAS2 RHOF LCK RASAL3 SYTL3

1.60e-04170211626178277bf9c7f2f06b5c0b03d4b69d78e9580c4
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX1 HEPH PTPRR RHOF RHOD TNS4

1.66e-0417121165d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCCC2 VWA2 CP VWA1 KYAT3 AADAT

1.66e-0417121168e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCelldroplet-Kidney-nan-21m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MCCC2 VWA2 CP VWA1 KYAT3 AADAT

1.66e-041712116007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NOX4 CYP4F3 PC ACSM2A ACSM2B PDZD2

1.66e-041712116f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellfacs-Liver-Non-hepatocytes-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX1 ATP2C2 ACAA2 ALAS2 AADAT PC

1.71e-041722116feaaf8ca7983d04a59ed0a7b3fb0e6d4b3a055f2
ToppCellfacs-Liver-Non-hepatocytes-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX1 ATP2C2 ACAA2 ALAS2 AADAT PC

1.71e-0417221168aed9c113f27d00401c272a3684495a4bc75bd0f
ToppCellfacs-Liver-Non-hepatocytes-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX1 ATP2C2 ACAA2 ALAS2 AADAT PC

1.71e-0417221169adfb4a65669cc536343616637058d0a4728013f
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCDN RNF19A ERN2 UBLCP1 NBAS TMEM26

1.76e-0417321168bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCDN RNF19A ERN2 UBLCP1 NBAS TMEM26

1.76e-0417321163e3c61468e703330788a10d850ef41a85680f86d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TCERG1L FMN1 CFAP221 COL5A2 LRRK1 KCNH5

1.76e-0417321169a2d42f8d9cb834856522661d524abb91c4637c5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TCERG1L BRCA2 COL5A2 LRRK1 TMEM26 KCNH5

1.76e-0417321168ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFAP221 ULK4 PROB1 CFAP70 CFAP43 ZDHHC23

1.82e-041742116f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellHealthy_Control-Lymphoid-NK-CD8_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DLG3 RHOF TNC LCK RASAL3 TNS4

1.82e-0417421165dddb822fa51b4020e4d9318acacd19c726091d6
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPHN INSM1 NUDT8 PCDHA13 NRSN1 KCNH5

1.82e-041742116271c51d220842402975d97c86c9acfdbdf62a32c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOF LCK RASAL3 SYTL3 IL2RG MX1

1.82e-0417421166b362b8a934a4fe6a1dd867b7c448cb3fb3ffd6a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGB8 NWD2 PXDN CPNE5 ZDHHC23 PDZD2

1.82e-041742116bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CFAP221 ULK4 PROB1 CFAP70 CFAP43 ZDHHC23

1.88e-041752116c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLRG2 ITGB8 ZDHHC14 CFAP43 LBR HYDIN

1.88e-041752116284fdc7a9d303636a637041846850d19d114861a
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK RHOF FMNL1 LCK RASAL3 SYTL3

1.88e-041752116f12e230a7d0d265542c5698231a3eb0876ac4cc8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPR3 CYP4F3 PC ACSM2A ACSM2B PDZD2

1.94e-0417621161595dbeee336a81e581325d63208ec6262664ee9
Drugdiaminoguanidine

CLTCL1 CLTC NOS1 CP

6.55e-06142104CID000151203
Drugphenylacetylglutamine

ARSA PC ACSM2A ACSM2B

8.87e-06152104CID000092258
Drug17-AAG; Up 200; 1uM; PC3; HG-U133A

CLTCL1 ACOX1 DNAJB5 ENGASE COL7A1 ICAM1 ST6GALNAC2 RSBN1 PC PDZD2

9.38e-0618621010432_UP
Drugmethylclofenapate

ACOX1 DDN SIGLEC1 HADHA

1.17e-05162104CID000030602
DrugTacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; PC3; HT_HG-U133A

DDN NCDN CLCN6 NOS1 MOCS1 B3GNTL1 NCOR2 ATP2C1 FUT4 EIF4G3

1.42e-05195210106698_DN
DrugTiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A

MPDZ CUL9 PDS5A DLG3 CLEC16A RHOD ERN2 ATP2C1 BBS7 DIP2C

1.42e-05195210107362_DN
DrugAminocaproic acid [60-32-2]; Down 200; 30.4uM; PC3; HT_HG-U133A

GPHN MPDZ CUL9 NCDN MTMR11 BRCA2 DLG3 ICAM1 ATP2C1 PAM

1.69e-05199210107258_DN
Drugoxygen

ACOX1 FMN1 CLTC NOS1 MOCS1 MPO RNF19A NOX4 CP CYP4F2 LBR PAM CYP4F22 CYP4F3 CYP4F12 CYP4F11

1.72e-0549921016CID000000977
DrugSulfinpyrazone [57-96-5]; Down 200; 9.8uM; HL60; HG-U133A

CLTCL1 GTF3C4 WIZ ALMS1 DDX54 NOS1 IFT27 RHOD ICAM1 ATP2C1

1.76e-05200210101574_DN
DrugChir-124

CLTC MPO HTR2B RHOD IL2RG

1.90e-05362105CID011502647
Drughexobarbital

ALAS2 NPR3 CYP4F2 CYP4F22 CYP4F3 CYP4F12 SIGLEC1 CYP4F11

2.40e-051272108CID000003608
Drug3-C-4

EVPL NPR3 RASA1 FUT4 SLC16A8

2.49e-05382105CID000118534
Disease1,5 anhydroglucitol measurement

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

4.10e-08292036EFO_0008009
Diseasevisceral adipose tissue measurement, body mass index

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1 NBAS

2.41e-06872037EFO_0004340, EFO_0004765
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2C2 ATP2C1 ATP2B2

6.32e-0662033DOID:0050429 (implicated_via_orthology)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

DLG3 PLXNB3 NCOR2 RASAL3 TANC1

2.19e-05492035DOID:0060037 (implicated_via_orthology)
DiseaseX-21319 measurement

ACSM2A ACSM2B

4.71e-0522032EFO_0800807
DiseaseX-11478 measurement

ACSM2A ACSM2B

1.41e-0432032EFO_0021242
DiseaseCombined molybdoflavoprotein enzyme deficiency

GPHN MOCS1

1.41e-0432032cv:C0268119
Diseaselymphocyte count

ZFPM1 ERVW-1 ALMS1 AHNAK PHLPP1 VWA2 CLEC16A RHOF B3GNTL1 PCDHGC5 PCDHGA11 RNF19A ICAM1 SPPL3 PCDHA6 RSBN1 ARSA RASAL3 CYP4F22 KYAT3 CYP4F3 SIGLEC1 ARRDC2

2.00e-04146420323EFO_0004587
DiseaseUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 measurement

EXOSC5 B3GNTL1

4.65e-0452032EFO_0802184
DiseaseHypoplastic Left Heart Syndrome

PCDHA9 PCDHA13

4.65e-0452032C0152101
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

4.65e-0452032EFO_0800378
Diseasenon-melanoma skin carcinoma

ZFPM1 PARD6B BRCA2 CLEC16A RNF19A DGKZ RSBN1 TRAK2

5.26e-042652038EFO_0009260
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

6.94e-0462032EFO_0800106
Diseasemyelofibrosis (implicated_via_orthology)

MPL NCOR2

6.94e-0462032DOID:4971 (implicated_via_orthology)
Diseaseamino acid measurement

CLTCL1 PXDN ALMS1 PTPRR FMN1 ULK4 ADGRL2 SPPL3 LRRK1 NBAS RASAL3 GRIP2 AADAT

8.94e-0467820313EFO_0005134
Diseasecorpus callosum central volume measurement

CLEC16A PIGO PDZD2

9.26e-04282033EFO_0010296
Diseaseneutrophil count, basophil count

PCDHA9 MPO PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1

9.57e-042242037EFO_0004833, EFO_0005090
Diseasesuberic acid measurement

TCERG1L PDZD2

9.67e-0472032EFO_0010534
DiseaseShock, Hemorrhagic

MPO ICAM1

9.67e-0472032C0036982
DiseaseDyskinetic syndrome

MYORG CP

9.67e-0472032C0013384
DiseaseColorectal Carcinoma

TCERG1L SPTBN2 NCDN DLG3 VWA2 PIGO MPO COL7A1 NTHL1 TGFBR1 BRF1 DIP2C TNS4

1.22e-0370220313C0009402
DiseaseEhlers-Danlos syndrome

SLC39A13 COL5A2

1.28e-0382032cv:C0013720
Diseasecocaine use disorder, social environment measurement

ADGRL2 TRAK2

1.28e-0382032EFO_0010445, EFO_0010552
Diseaseresponse to anti-thyroid drug, Drug-induced agranulocytosis

EHMT2 MOS

1.28e-0382032EFO_0007838, HP_0012235
DiseasePolydactyly

CEP120 ALMS1 IFT27 LBR BBS7

1.32e-031172035C0152427
DiseaseEhlers-Danlos syndrome (is_implicated_in)

SLC39A13 COL5A2

1.64e-0392032DOID:13359 (is_implicated_in)
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

1.64e-0392032EFO_0800562
Diseaseneuroticism measurement, cognitive function measurement

PCDHA9 DDN NOS1 L3MBTL2 PCDHA13 PCDHA8 PCDHA6 PCDHA3 PCDHA1 HECTD2 EIF4G3

1.98e-0356620311EFO_0007660, EFO_0008354
Diseaseasthma, allergic disease

NRROS ITGB8 CLEC16A IKZF4

2.18e-03792034MONDO_0004979, MONDO_0005271
DiseaseGlobal developmental delay

SPTBN2 POLR2A NBAS P4HTM AGO1

2.31e-031332035C0557874
Diseasepost-traumatic stress disorder symptom measurement

PCDHA8 PCDHA6 PCDHA3 PCDHA1

2.50e-03822034EFO_0008535
Diseasepost-traumatic stress disorder

NOS1 ZDHHC14 PCDHA8 PCDHA6 PCDHA3 PCDHA1

2.83e-032022036EFO_0001358
Diseaseretinopathy of prematurity (biomarker_via_orthology)

NOS1 ICAM1

2.97e-03122032DOID:13025 (biomarker_via_orthology)
Diseaseevent free survival time, type 1 diabetes mellitus, autoantibody measurement

TTC34 RSBN1

2.97e-03122032EFO_0000482, EFO_0004866, MONDO_0005147
Diseasedisks large homolog 3 measurement

ZFPM1 DLG3

2.97e-03122032EFO_0802472
DiseaseDystonia

KMT2B MYORG CP ARSA

2.97e-03862034C0013421
DiseaseChildhood Medulloblastoma

BRCA2 MPL L3MBTL2

3.23e-03432033C0278510
DiseaseMelanotic medulloblastoma

BRCA2 MPL L3MBTL2

3.23e-03432033C1275668
DiseaseMedullomyoblastoma

BRCA2 MPL L3MBTL2

3.23e-03432033C0205833
DiseaseDesmoplastic Medulloblastoma

BRCA2 MPL L3MBTL2

3.23e-03432033C0751291
DiseaseAdult Medulloblastoma

BRCA2 MPL L3MBTL2

3.23e-03432033C0278876
DiseaseDiabetes, Autoimmune

NOS1 CLEC16A CP

3.45e-03442033C0205734
DiseaseBrittle diabetes

NOS1 CLEC16A CP

3.45e-03442033C0342302
DiseaseDiabetes Mellitus, Sudden-Onset

NOS1 CLEC16A CP

3.45e-03442033C4554117
DiseaseDiabetes Mellitus, Ketosis-Prone

NOS1 CLEC16A CP

3.45e-03442033C3837958
DiseaseBardet-Biedl Syndrome

ALMS1 IFT27

3.49e-03132032C0752166
DiseaseDiabetes Mellitus, Insulin-Dependent

NOS1 CLEC16A CP

3.68e-03452033C0011854
Diseasediabetic retinopathy (biomarker_via_orthology)

NOS1 NPR3 ICAM1

3.68e-03452033DOID:8947 (biomarker_via_orthology)
Diseasedimethylglycine measurement

ADGRL2 ZDHHC14 GRIP2

3.92e-03462033EFO_0010476
Diseaseskin melanoma (is_implicated_in)

BRCA2 ICAM1

4.06e-03142032DOID:8923 (is_implicated_in)
DiseaseGeneralized hypotonia

POLR2A AGO1

4.66e-03152032C1858120
DiseaseMedulloblastoma

BRCA2 MPL L3MBTL2

4.96e-03502033C0025149
Diseasehypertension (biomarker_via_orthology)

NOS1 NOX4 CYP4F2 CYP4F12 CYP4F11 ATP5F1A

4.99e-032272036DOID:10763 (biomarker_via_orthology)
DiseaseUrticaria

MPO ICAM1

5.30e-03162032C0042109
DiseaseDrug-induced agranulocytosis

ADGRL2 TMEM26

5.30e-03162032HP_0012235
DiseaseConvulsions

MPDZ DBT NOS1 PAM

5.47e-031022034C4048158
DiseaseUremia

ICAM1 TGFBR1

5.98e-03172032C0041948
Diseasepulmonary hypertension (implicated_via_orthology)

TNC TGFBR1 ATP5F1A

6.15e-03542033DOID:6432 (implicated_via_orthology)
Diseaseanthropometric measurement

ITGB8 CEP120 NPR3 POLR2A PAM

6.24e-031682035EFO_0004302
Diseasefrontal pole volume measurement

NOS1 DIP2C

6.70e-03182032EFO_0010304
DiseaseDisorder of organic acid metabolism

MCCC2 DBT

6.70e-03182032cv:C1263739

Protein segments in the cluster

PeptideGeneStartEntry
VKLRDGIPGVPSLAV

ZNF280A

181

P59817
QLEGLPPGTKVTIRA

ZNF280D

506

Q6N043
VPVRAVKEGTLGLTP

EPB42

366

P16452
LRQKLPPGAEAGTVL

SLC4A9

216

Q96Q91
IGFLTGPKPLIERVI

AADAT

271

Q8N5Z0
LISIGIAIPVPIKGI

HTR2B

181

P41595
GPLLVPRVKVAEDGS

BDP1

241

A6H8Y1
LPGPKIARLELGGVI

BBS7

61

Q8IWZ6
PVLVCKDPIRTVGLG

ADPGK

466

Q9BRR6
PVLPLSAIAGLVGKE

CFAP43

226

Q8NDM7
GKPDPVVLQGIIRSL

CCDC61

141

Q9Y6R9
IKPGTVKRLRGEGLP

DNAJB5

296

O75953
LPVPGVLLKEFTVSG

CTAG1A

116

P78358
LPSLVCVITGKGPLR

ALG1L2

96

C9J202
VVPTRLPGSAGELAL

ADAMTS8

41

Q9UP79
VLPPGTEGDIGIRVK

ACSM2A

401

Q08AH3
TEGDIGIRVKPIRPI

ACSM2A

406

Q08AH3
RPGIGTVGKPIKLLA

AGO1

26

Q9UL18
PDLTEVTLKAIGVPG

ALMS1

1866

Q8TCU4
PKVKGGVDVTLPRVE

AHNAK

581

Q09666
LELTLPVKPVIGGSS

ADGRL2

1281

O95490
LIKEPGSGVPVVLIT

PAM

856

P19021
VGLPLGPGREALEKA

EHMT2

621

Q96KQ7
GKELGLRVSAEPTPL

AHDC1

506

Q5TGY3
RPEPGKGVVEKSLGL

DDN

306

O94850
KRAVVASLAGEPVGP

ARRDC2

236

Q8TBH0
ICRRLKTSPVEGLPG

ATP2B2

56

Q01814
LVGIIDPPRTGVKEA

ATP2C1

541

P98194
LVGIIDPPRVGVKEA

ATP2C2

571

O75185
RVGLKAPGIIPRISV

ATP5F1A

171

P25705
AAARGAKPDLILGPV

NPR3

121

P17342
GKPIQSLLLPARGEI

NWD2

1316

Q9ULI1
PTLGPLTRLEGIKVG

P4HTM

106

Q9NXG6
GFEITPPVVLRLKCG

NPM1

91

P06748
APGPARTLTLIAKVI

RASAL3

631

Q86YV0
DKFIIPGSPAIISIR

PCDHA9

886

Q9Y5H5
TRVLLLTGKPKPAGV

PDS5A

1126

Q29RF7
IPLKGIEPGSLRVRA

RASA1

696

P20936
RLVPGETLEKSLGPG

FMN1

596

Q68DA7
KATVVPVLAGVGPLD

NUDT8

111

Q8WV74
LDGGDPIRKGAVPIR

PCDHGA11

216

Q9Y5H2
PVCGIRGKTLIINLP

GPHN

131

Q9NQX3
PIGKVVEGTPLIDGR

LBR

276

Q14739
VPSLLGPRVIGKVSA

ODF3B

146

A8MYP8
DKFIIPGSPAIISIR

PCDHA6

886

Q9UN73
LEKVPGIFISRLVPG

PARD6B

186

Q9BYG5
AVLIGPPSAGRLVDV

SLC16A8

391

O95907
PKDIASGLIGPLIIC

CP

186

P00450
IGPPDLVERKGSLTL

CFAP95

21

Q5VTT2
PEVAIGALGSIKAIP

DBT

416

P11182
PPRLGTVGLSIKVTD

PCDH19

216

Q8TAB3
SIARGAPVIVPELGK

NCOR2

1521

Q9Y618
DKFIIPGSPAIISIR

PCDHA8

886

Q9Y5H6
DKFIIPGSPAIISIR

PCDHA3

886

Q9Y5H8
ALRLFSKVRPPVGGI

KIAA0100

1986

Q14667
GPREILIKEGAPSLL

NCDN

476

Q9UBB6
LAGPPLVKAATGEEV

MCCC2

241

Q9HCC0
VPEVLKRLQSLGVPG

MDP1

51

Q86V88
LEPLTVGPKGVLSVT

GGNBP2

111

Q9H3C7
PGVRKGLEPELSGTL

MTMR11

56

A4FU01
GLVQPKKTGSRPVVL

LIPM

81

Q5VYY2
GARKISSEPVPGEII

L3MBTL2

656

Q969R5
LSKGIRPVLGQPEEV

LRRK1

1476

Q38SD2
LLAGAVPVVLGPDRA

FUT4

431

P22083
VQPGPRVLKVLVGEA

HMCN2

1166

Q8NDA2
TGVALVPRGLTLAPA

ERN2

306

Q76MJ5
REKLPPIVSAGAGAT

HECTD2

31

Q5U5R9
VGPGGEVISDPKLIR

KCNH5

271

Q8NCM2
LTLARPLKEPSGVAG

DDX54

461

Q8TDD1
SSIGLKTVIGELPPA

CAND1

106

Q86VP6
AGSPLKIDLRPVLGE

CAND1

636

Q86VP6
KIDLRPVLGEGVPIL

CAND1

641

Q86VP6
LTAVVPDIPGFRKIL

HMGXB3

111

Q12766
VATVGLVVPLPGRDL

PLXNB3

171

Q9ULL4
AGLIVIFRGPVATIP

OR51M1

156

Q9H341
VLRVGIPENAPIGTL

PCDHGC5

246

Q9Y5F6
GLLSRKTIPLEPGIG

PDZD2

2726

O15018
KTIPLEPGIGRSVAV

PDZD2

2731

O15018
GVSEPLKRKGRVGPL

MPO

646

P05164
TGGLIDPKRTGRIPI

EVPL

1941

Q92817
GLTVLAVGFLVPPKI

NRSN1

76

Q8IZ57
VTKPVPAGGLLSVLL

ZFPM1

176

Q8IX07
PIVPLDGKGTLLIRN

LCK

26

P06239
PELLVPEKAAVSGGR

KIF26A

931

Q9ULI4
PCLAPIKVALDVGRG

POLG2

376

Q9UHN1
SCGGLPPVRSALEKI

TUBGCP4

161

Q9UGJ1
LRPGIGEKPTVVTVE

GABRE

86

P78334
PLEKARIAGVGSLPL

KMT2B

771

Q9UMN6
VLVPSSRGGLPLEEV

ARSA

91

P15289
LEVILRPKIGLPGVA

EXOSC5

76

Q9NQT4
RPKIGLPGVAEKSRE

EXOSC5

81

Q9NQT4
ALKPGRAVEGPSTVL

MON2

721

Q7Z3U7
GGPRDPLKVLEGVVA

NBAS

2056

A2RRP1
CPVLARGPTSLLGKV

ALAS2

11

P22557
KIRLTGGEPLIRPDV

MOCS1

121

Q9NZB8
PRKLLFTTVPGLTGV

NOX4

151

Q9NPH5
VSKPPVIISDLIRGG

NOS1

36

P29475
VVVDPQGRGAPEIKA

PTPRR

301

Q15256
DKFIIPGSPAIISIR

PCDHA1

886

Q9Y5I3
DKFIIPGSPAIISIR

PCDHA13

886

Q9Y5I0
PLLPGTIAGEIESKA

ITGB8

356

P26012
APPGVRSVKVVLVGD

RHOD

11

O00212
IVPIREIGTHKPLPG

ACOX1

206

Q15067
PVPVINLKDGTRLAG

CHD9

2486

Q3L8U1
LLVLIEPVAAGSGIP

CLCN6

146

P51797
KARSQAPGISLPGVL

IFT27

106

Q9BW83
GPVLVAKGRSTLPIC

HYDIN

3936

Q4G0P3
GDEKLPRAVTLTGLP

KLRG2

241

A4D1S0
KRRGEPLILVGEPSI

BRCA2

2271

P51587
RDGKVPAILAGLDPR

CEP120

151

Q8N960
ITRVPLVTIPKGKAG

CFAP70

311

Q5T0N1
TVLAGRLLPPGAVVA

CTU1

41

Q7Z7A3
TPVDRPVLTKVGKGE

CMYA5

1381

Q8N3K9
FVLPDGRVIPKGIVC

CYP4F11

406

Q9HBI6
IVLPDGRVIPKGITC

CYP4F12

406

Q9HCS2
VPILKRKLPGSDVSG

FBXO28

216

Q9NVF7
SGKILPGVRIIIANP

DIP2C

1346

Q9Y2E4
PHIIRIGDLKPTGEI

DENND6A

366

Q8IWF6
RLPIIDLAPVDVGGT

COL5A2

1471

P05997
IVLPDGRVIPKGIIC

CYP4F2

406

P78329
TKAKLIPTGRDVGPV

DLG3

71

Q92796
SERLCLVSEIPPKGG

IL2RG

326

P31785
ILRGPGDAVSIEILP

FMNL1

491

O95466
KTVLGTPEVLLGALP

HADHA

166

P40939
IDTRVRGVEVLGPKP

CUL9

1286

Q8IWT3
ARPGVPKVCILITDG

COL7A1

136

Q02388
VSPSKVILPRGGSVL

ICAM1

31

P05362
IVLPDGRVIPKGIIC

CYP4F3

406

Q08477
KPLIAVVNGPAVGIS

ECI2

236

O75521
GGSSLLVRGVIPPEV

ENGASE

461

Q8NFI3
QSPGPLALKIAGRIA

EMC9

91

Q9Y3B6
LKEASVPLGTVVVPG

DGKZ

666

Q13574
PFDPIVISGLTKRGL

GRIP2

676

Q9C0E4
PAAEPGLGAVVRSIK

SLC39A13

201

Q96H72
EFSKPLLPVGRAGVL

EIF4G3

1341

O43432
PRELFKLVVGGLLSP

NOC4L

146

Q9BVI4
PDGRIIPKGIICLVS

CYP4F22

416

Q6NT55
LRGTPGPSKEVLRVV

IKZF4

506

Q9H2S9
LLESVGLKPIVPDGG

KYAT3

356

Q6YP21
EIVGSPGSRLEKPLT

CPNE5

121

Q9HCH3
KIIRVTELPGGVPRD

NRROS

626

Q86YC3
KPRGTLQLAGAVISP

OSBPL11

101

Q9BXB4
LGLKIKEGPVEAPRG

INSM1

241

Q01101
RAPELLKGEGVTPKA

MOS

246

P00540
APDGLGLVPIKSSEV

CFAP221

551

Q4G0U5
LPPTVSVLALVKRGA

RUSC1

811

Q9BVN2
ERTGGVPLIKAPKRE

RSBN1

221

Q5VWQ0
VLGAKNLPVRPDGTL

SYTL3

486

Q4VX76
AAPGPGRKELKIVIV

RHOF

11

Q9HBH0
STLKRVAGVIVPPEG

RNF133

66

Q8WVZ7
KRVPILPFVIGAGVL

ERVW-1

316

Q9UQF0
PVLREEKLPVVGIGK

TRMT13

251

Q9NUP7
VGLGSKPVRLSVAIP

TRNAU1AP

161

Q9NX07
SKEGLAIPLRGSPVT

TMEM26

346

Q6ZUK4
IAELKLREAPSPTGG

SGTA

201

O43765
ESTGGKRLLIPVVPG

MRM3

371

Q9HC36
ASVAELVALPGVGPK

NTHL1

206

P78549
APRDIATGLIGPLIT

HEPH

191

Q9BQS7
AVPGDVLVLTKPLGT

SEPHS1

191

P49903
RSAILGVPVPEGLDK

ST6GALNAC2

241

Q9UJ37
GKSLREPVAQPGLLL

TANC1

1511

Q9C0D5
SSLKEVVAGAPRPGL

WIZ

936

O95785
VVAGAPRPGLLSLAK

WIZ

941

O95785
PTGTVILLCKGRVPE

SKIV2L

711

Q15477
AAPLGKVLVDPESGR

PROB1

876

E7EW31
RASRVVKLEGPGPAL

SOX30

161

O94993
KSSPGLGPVELAAVI

TGFBR1

116

P36897
APGGRPDLLIAVKSV

B3GNT9

111

Q6UX72
RPPFVICVKLDLTGG

B3GNTL1

326

Q67FW5
VLPPGTEGDIGIRVK

ACSM2B

401

Q68CK6
TEGDIGIRVKPIRPI

ACSM2B

406

Q68CK6
KVNPSRLPVVIGGLL

CLTC

806

Q00610
LLSVLRPAGPVAVGI

CHPF

6

Q8IZ52
KVNPSRTPAVIGGLL

CLTCL1

806

P53675
PTGTPLTGIDFVKRL

CLEC16A

641

Q2KHT3
RHVGLRVGIPKETPA

ACAA2

71

P42765
SAGLLRLSAGVVVPP

TCERG1L

46

Q5VWI1
AEASGARPGVPKVLV

VWA1

126

Q6PCB0
LGTILDPRPGVITKG

TRAK2

581

O60296
PVLRGLKTAEGALRP

TTLL8

731

A6PVC2
VGPLALPVGKARQLI

ZWILCH

96

Q9H900
SGTVRIGVAKPLPLS

MPDZ

776

O75970
APVGIALIAGIAIPA

RNF19A

371

Q9NV58
EVLSGEILPKPTKGR

SPTBN2

96

O15020
ILTGETAEGLPPVRI

SLC26A11

271

Q86WA9
PVGLGEPGLLLTKVV

SLC27A5

486

Q9Y2P5
VASPRLEKRLGGLAP

TNS4

251

Q8IZW8
VGRDVPRLSLPGKLV

SPPL3

241

Q8TCT6
APVRLTGLVTVLGPL

WDR97

146

A6NE52
LRRGLKAEAVKGPVP

PRX

166

Q9BXM0
LRVIFPTGDSKVVLP

POLR2A

966

P24928
PTPLLLEVKARAIGI

TRIM75

401

A6NK02
PGGKEAETRQPVVIL

TMEM53

26

Q6P2H8
ALVVEDLVPGSRLGP

PXDN

1216

Q92626
TVPGSLRAVDIPGLK

TNC

1121

P24821
ASGVALPPVGVLSLR

PTH2

31

Q96A98
DGEIVGLSGRVLKIP

TPP2

86

P29144
RGARPGVPKAVVVLT

VWA2

626

Q5GFL6
GDPVLRTGKPLSVEL

ATP6V1A

76

P38606
VKILLSPSGRNILPG

SIGLEC1

241

Q9BZZ2
KVLEPPLGARGGTLE

MPL

436

P40238
LIVGSAFGPIKILPV

GTF3C4

331

Q9UKN8
LGTAGPSPVTRVLLK

IGSF9

401

Q9P2J2
GADPVTSVGKRLRPL

BRF1

581

Q92994
LAVKITPAIPAVAGI

ZDHHC14

86

Q8IZN3
VPKGRVGPVQLAVLT

ZDHHC23

161

Q8IYP9
EALLGPGTTAIRCPK

TTLL9

6

Q3SXZ7
TPRRGLIDVKPLGVI

UBLCP1

221

Q8WVY7
VLGLVPQALPKADGR

ZNF687

441

Q8N1G0
KPVTVLVKAGAGAPR

PIGO

761

Q8TEQ8
VIEVATDAPLRKPGG

PHLPP1

1636

O60346
LEGLPPGAKVTIRAS

ZNF280C

501

Q8ND82
PGAKVTIRASLGPLQ

ZNF280C

506

Q8ND82
LPEGIRAGPVSSVLL

VSIG10L

531

Q86VR7
VSALKLGPGTVVPEL

TTC34

236

A8MYJ7
KVLKDLPRVEGRPGA

PC

966

P11498
DISPRKILLEGPGTL

ULK4

121

Q96C45
ATGPPGQKLLIIRSA

ZNF628

966

Q5EBL2
RPGQLSLLEGKPVVV

GARIN5B

741

Q8N5Q1
PPLRVNVVLSGLLGK

LONRF3

221

Q496Y0
PRGSGIVTRCPLVLK

MX1

96

P20591
IGDTLLVAPVLEPGK

MYORG

656

Q6NSJ0