Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentapolipoprotein B mRNA editing enzyme complex

A1CF RBM47

4.31e-055442GO:0030895
GeneOntologyCellularComponentmRNA editing complex

A1CF RBM47

9.03e-057442GO:0045293
GeneOntologyCellularComponentspectrin

SPTAN1 SPTBN1

1.54e-049442GO:0008091
GeneOntologyCellularComponentcuticular plate

SPTAN1 SPTBN1

3.33e-0413442GO:0032437
GeneOntologyCellularComponentaxon

TAOK2 ABR KIF1A SPTAN1 ATCAY SPTBN1 LMTK3 CNGB1

4.78e-04891448GO:0030424
DomainHnRNP_R/Q_splicing_fac

A1CF RBM46 RBM47

1.59e-075483IPR006535
DomainSpectrin

SPTAN1 SPTBN1

1.58e-0323482PF00435
DomainSpectrin_repeat

SPTAN1 SPTBN1

2.51e-0329482IPR002017
DomainSpectrin/alpha-actinin

SPTAN1 SPTBN1

3.05e-0332482IPR018159
DomainSPEC

SPTAN1 SPTBN1

3.05e-0332482SM00150
Domain-

MKRN3 ZC3H13

4.74e-03404824.10.1000.10
DomainZnF_C3H1

MKRN3 ZC3H13

6.77e-0348482SM00356
Domainzf-CCCH

MKRN3 ZC3H13

7.04e-0349482PF00642
DomainZnf_CCCH

MKRN3 ZC3H13

9.76e-0358482IPR000571
DomainZF_C3H1

MKRN3 ZC3H13

9.76e-0358482PS50103
DomainCH

SPTBN1 LIMCH1

1.21e-0265482SM00033
DomainCH

SPTBN1 LIMCH1

1.40e-0270482PF00307
Domain-

SPTBN1 LIMCH1

1.44e-02714821.10.418.10
DomainCH

SPTBN1 LIMCH1

1.51e-0273482PS50021
Pubmed

ZNF674: a new kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation.

ZNF674 KRBOX4

2.03e-06250216385466
Pubmed

Spectrin-actin interaction is required for neurite extension in NB 2a/dl neuroblastoma cells.

SPTAN1 SPTBN1

2.03e-0625028776664
Pubmed

Cloning of a portion of the chromosomal gene and cDNA for human beta-fodrin, the nonerythroid form of beta-spectrin.

SPTAN1 SPTBN1

2.03e-0625028406479
Pubmed

Identification of a mouse brain beta-spectrin cDNA and distribution of its mRNA in adult tissues.

SPTAN1 SPTBN1

2.03e-0625021742606
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

KIF1A SPTAN1 SPTBN1 LIMCH1 LMTK3 DENR PRRC2B

5.10e-0647550731040226
Pubmed

Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver.

A1CF RBM47

6.07e-06350230309881
Pubmed

The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences.

SPTAN1 SPTBN1

6.07e-0635028479293
Pubmed

Comparison of RNA Editing Activity of APOBEC1-A1CF and APOBEC1-RBM47 Complexes Reconstituted in HEK293T Cells.

A1CF RBM47

6.07e-06350230844405
Pubmed

Interaction of the C-terminal domain of delta glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells.

SPTAN1 SPTBN1

6.07e-06350210576550
Pubmed

Developmental expression of brain beta-spectrin isoform messenger RNAs.

SPTAN1 SPTBN1

6.07e-0635021467942
Pubmed

alpha -Catenin binds directly to spectrin and facilitates spectrin-membrane assembly in vivo.

SPTAN1 SPTBN1

6.07e-06350211069925
Pubmed

Phosphorylation of a threonine unique to the short C-terminal isoform of betaII-spectrin links regulation of alpha-beta spectrin interaction to neuritogenesis.

SPTAN1 SPTBN1

1.21e-05450217088250
Pubmed

Brain beta spectrin isoform 235 (Spnb-2) maps to mouse chromosome 11.

SPTAN1 SPTBN1

1.21e-0545021638088
Pubmed

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

SPTAN1 SPTBN1

1.21e-05450221566095
Pubmed

Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.

SPTAN1 SPTBN1

1.21e-05450212820899
Pubmed

Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.

SPTAN1 SPTBN1

1.21e-0545023862089
Pubmed

A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly.

SPTAN1 SPTBN1

2.02e-05550222632975
Pubmed

The prototypical 4.1R-10-kDa domain and the 4.1g-10-kDa paralog mediate fodrin-actin complex formation.

SPTAN1 SPTBN1

2.02e-05550211274145
Pubmed

ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.

SPTAN1 SPTBN1

3.03e-05650237069398
Pubmed

Identification of transcriptionally regulated mRNAs from mouse Schwann cell precursors using modified RNA fingerprinting methods.

SPTAN1 SPTBN1

3.03e-0565029211987
Pubmed

Knockout mice with pituitary malformations help identify human cases of hypopituitarism.

SPTBN1 PRRC2B MKS1

3.80e-054550338822427
Pubmed

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.

A1CF RBM47

4.23e-05750224916387
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TAOK2 ZNF219 ABR SPTAN1 SPTBN1 LIMCH1 LMTK3 PRRC2B

6.43e-0596350828671696
Pubmed

Disruption of axo-glial junctions causes cytoskeletal disorganization and degeneration of Purkinje neuron axons.

SPTAN1 SPTBN1

7.25e-05950216551741
Pubmed

USP7 controls NGN3 stability and pancreatic endocrine lineage development.

SPTAN1 SPTBN1 CHGA

8.16e-055850337117185
Pubmed

USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.

SPTAN1 SPTBN1

9.05e-051050236653359
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

SPTAN1 SPTBN1

9.05e-051050222159418
Pubmed

Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.

SPTAN1 SPTBN1

1.10e-041150217607528
Pubmed

OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis.

SPTAN1 SPTBN1

1.10e-041150236411454
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

CRACD SPTBN1 LIMCH1

1.26e-046750329254152
Pubmed

alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.

SPTAN1 SPTBN1

1.56e-041350218796539
Pubmed

Menin determines K-RAS proliferative outputs in endocrine cells.

RASSF1 CHGA

2.10e-041550225133424
Pubmed

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.

SPTBN1 MKS1

2.40e-041650223870131
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

TAOK2 ABR PRRC2B

3.01e-049050315033168
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTAN1 SPTBN1

3.05e-041850212119179
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SPTAN1 SPTBN1 LMTK3 PRRC2B

3.44e-0423150416452087
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

RASSF1 SPTBN1 ANKS4B RBM47 DENR PRRC2B MKS1 DOP1B

3.66e-04124250830973865
Pubmed

CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity.

SPTAN1 CHGA

3.79e-042050219726564
Pubmed

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.

SPTAN1 SPTBN1

3.79e-042050218723693
Pubmed

Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes.

SPTAN1 SPTBN1

4.18e-042150212202484
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

TAOK2 ABR SPTAN1 SPTBN1

4.70e-0425150427507650
Pubmed

NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.

SPTAN1 SPTBN1

5.95e-042550230309841
Pubmed

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

SPTAN1 SPTBN1

5.95e-04255028493579
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

SPTAN1 SPTBN1 LIMCH1

6.64e-0411850330979931
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

TAOK2 A1CF SPTAN1 SPTBN1 LIMCH1 RBM47 DENR PRRC2B

7.02e-04137150836244648
Pubmed

E3 Ubiquitin Ligase UBR5 Promotes the Metastasis of Pancreatic Cancer via Destabilizing F-Actin Capping Protein CAPZA1.

SPTAN1 SPTBN1

9.17e-043150233777788
Pubmed

Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation.

SPTAN1 SPTBN1

1.31e-033750223180766
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

SPTAN1 SPTBN1 UST PRRC2B

1.33e-0333250437433992
CytobandEnsembl 112 genes in cytogenetic band chr15q11

MKRN3 GOLGA6L2 GOLGA6L22 GOLGA6L1

9.43e-05217504chr15q11
Cytoband8q22

TP53INP1 RUNX1T1

1.21e-04155028q22
Cytoband10q11.23

A1CF WDFY4

6.01e-043350210q11.23
CytobandXp11.3

ZNF674 KRBOX4

7.56e-0437502Xp11.3
Cytoband15q11.2

GOLGA6L2 GOLGA6L22 GOLGA6L1

8.90e-0417250315q11.2
GeneFamilyEF-hand domain containing|Spectrins

SPTAN1 SPTBN1

6.34e-0573221113
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500

LCA5 TP53INP1 KIF1A ATCAY EFCC1 RBM47 APOBR MKS1

1.69e-05488508Facebase_RNAseq_e10.5_Medial Nasal Eminence_500
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_200

RSPH1 ERCC6L RBM46 RUNX1T1 RBM47

2.14e-05143505gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#1

LCA5 TP53INP1 EFCC1 RBM47 APOBR MKS1

6.02e-05291506Facebase_RNAseq_e10.5_Medial Nasal Eminence_500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000

LCA5 CSF2RA TP53INP1 KIF1A ATCAY EFCC1 LIMCH1 RBM47 APOBR MKS1

7.92e-059795010Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

ANO4 CRACD SPTAN1 ATCAY RUNX1T1 DOP1B

9.66e-08200506306926cb7a847871641f02e03d52dc56fd55711c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MKRN3 ZNF219 KIF1A CNGB1 DOP1B

1.50e-06174505271c51d220842402975d97c86c9acfdbdf62a32c
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM130 KIF1A ATCAY CHGA RUNX1T1

1.98e-061845053da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM130 KIF1A ATCAY CHGA CNGB1

2.03e-061855053d6711030ca4328357b06d5497cf98cdefcd7f4f
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRACD ABR CSF2RA TRH WDFY4

2.03e-0618550553a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 CSF2RA KIF1A CHGA PRRC2B

2.50e-06193505471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 CSF2RA KIF1A CHGA PRRC2B

2.50e-06193505fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 CSF2RA KIF1A CHGA PRRC2B

2.56e-061945053a3ecedcdc7691cf21775818b598208fcb980c29
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 CSF2RA KIF1A CHGA PRRC2B

2.56e-061945050b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

KIF1A ATCAY CHGA RUNX1T1 CNGB1

2.76e-06197505c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM130 KIF1A ATCAY CHGA CNGB1

2.83e-061985057b9c7ce5d6b7df8db85943b65da1a2c202a8bb53
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANO4 ANKRD35 CACNA1D KIF1A CHGA

2.83e-06198505d6812494874be0c14361ac2ac3e418b335bb8f55
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM130 KIF1A ATCAY CHGA CNGB1

2.90e-06199505646d6e84a2e70042ee5d68a045abb3fc6741fcc7
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABR CSF2RA RBM47 APOBR WDFY4

2.90e-0619950522001aa733273e784051b7f750e07d99aaf7a225
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CRACD SPTAN1 ATCAY RUNX1T1 DOP1B

2.90e-06199505a255484ba77bd2741a541da278efc8cf4abbe570
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

KIF1A SPTAN1 SPTBN1 LIMCH1 RUNX1T1

2.90e-06199505058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

SPTAN1 ATCAY LIMCH1 RUNX1T1 DOP1B

2.97e-0620050584e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-Neurons|GW19 / Sample Type, Dataset, Time_group, and Cell type.

SPTAN1 ATCAY LIMCH1 RUNX1T1 DOP1B

2.97e-06200505b9538eb33ac86384e7e289a5a82fac4d56a7b9c2
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Cortical_neuron|5w / Sample Type, Dataset, Time_group, and Cell type.

KIF1A ATCAY SPTBN1 CHGA RUNX1T1

2.97e-06200505085060d148158f7d9e938b6c4a3700ccbb3bca15
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

KIF1A SPTAN1 ATCAY SPTBN1 PRRC2B

2.97e-06200505c92e4fc0442404481fcac623d691dae6215b852d
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

KIF1A SPTAN1 SPTBN1 LIMCH1 RUNX1T1

2.97e-06200505db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

KIF1A SPTAN1 SPTBN1 LIMCH1 RUNX1T1

2.97e-0620050530a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CRACD SPTAN1 LIMCH1 RUNX1T1 DOP1B

2.97e-062005055b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital|World / Primary Cells by Cluster

KIF1A SPTAN1 SPTBN1 LIMCH1 RUNX1T1

2.97e-062005056bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19|World / Primary Cells by Cluster

KIF1A SPTAN1 SPTBN1 LIMCH1 RUNX1T1

2.97e-06200505c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCellIPF-Epithelial-PNEC|IPF / Disease state, Lineage and Cell class

ANO4 TRH KIF1A CHGA

3.05e-05159504adec82df944fe8699a69ca52534353bef100f2f9
ToppCellIPF-Epithelial-PNEC|World / Disease state, Lineage and Cell class

ANO4 TRH KIF1A CHGA

3.20e-05161504133833729ba8b6d3eef326590ca7476b17602cbb
ToppCellIPF-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

TRH KIF1A CHGA RUNX1T1

3.28e-05162504865d0e215d54fb1412f00cf0649c71c2f1878e57
ToppCellfacs-MAT-Fat-3m-Myeloid-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH RBM47 WDFY4

3.44e-051645041250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCellfacs-MAT-Fat-3m-Myeloid|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH RBM47 WDFY4

3.44e-05164504fa0d77b648cde5e42b9394e877168c80de238bde
ToppCellfacs-Trachea-nan-18m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH RBM47 WDFY4

3.87e-05169504c6ae131f0bfb757541322691311139fae8bdca21
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH APOBR WDFY4

4.05e-051715040385d5834ae16bbb0c6a68893fec60e4dd1e478d
ToppCellfacs-Trachea-nan-18m-Myeloid|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH RBM47 WDFY4

4.05e-051715049d496a6edac9663791cda684188d49895246f6fe
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH APOBR WDFY4

4.05e-05171504a3e3fe0cbab21abb178c482f5951e576529f7e30
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CSF2RA ANKS4B APOBR WDFY4

4.14e-0517250472fbfa890995e47048b47199c170cc7dcd7661f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CSF2RA ANKS4B APOBR WDFY4

4.14e-051725042ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCellfacs-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH RBM47 WDFY4

4.24e-051735044e9b6c71030ae0d63d54e7255e4a10b25970fcc4
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RA TRH RBM47 WDFY4

4.33e-05174504d67fc8e30cc67fff8f7fdeaccb409d12ca0992c1
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RA TRH ZNF467 WDFY4

4.43e-05175504393da565f61ba640410419a0cabaaf5c1056580a
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RA TRH ZNF467 WDFY4

4.43e-05175504271b56d4ab940959d28ca4b86ce2750350dfc717
ToppCellfacs-Trachea-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RA TRH RBM47 WDFY4

4.43e-0517550422fd7d9b4d403cc8061316855f78bad0eb705ce9
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RA RBM47 APOBR WDFY4

4.43e-051755044655d3daa95e8ffa7d5ee4180de06b2fec361bfb
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CSF2RA TRH ZNF467 WDFY4

4.43e-051755045168340c6045bbc7d67276afb719b051d1cb65a2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANO4 RBM46 LIMCH1 UST

4.53e-0517650405ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellfacs-Lung-EPCAM-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH RBM47 WDFY4

4.63e-05177504e73e2b6a72630bb56ac2af1cdeedc8f0f828f390
ToppCellfacs-Lung-EPCAM-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH RBM47 WDFY4

4.73e-0517850401c90c3952220cc4d6a7ed9c4d575fe4f2f80fd1
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D TRH TP53INP1 RBM47

4.73e-05178504b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCellCOPD-Epithelial-PNEC|Epithelial / Disease state, Lineage and Cell class

ANO4 KIF1A CHGA RUNX1T1

4.84e-05179504988d0853c391da1e5004f73f3678047418d3f6d3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A ATCAY CHGA CNGB1

5.05e-051815047f99002a6411117cc2361334c7c9228e20c574b4
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRACD TMEM130 LIMCH1 ZNF467

5.16e-05182504f2a1784ffcba9b27132e0db21e574cbd8a0a6418
ToppCell367C-Myeloid-Dendritic-cDC1|367C / Donor, Lineage, Cell class and subclass (all cells)

CSF2RA ZNF467 APOBR WDFY4

5.16e-051825046f5228ac47f9ab46d165740cf2655b5ba217acbe
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A ATCAY CHGA CNGB1

5.27e-051835047e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF1A ATCAY CHGA CNGB1

5.27e-051835049dfb398b9995d562864fe688861a831ada0814cd
ToppCelltumor_Lung-Myeloid_cells-CD141+_DCs|tumor_Lung / Location, Cell class and cell subclass

CSF2RA ZNF467 APOBR WDFY4

5.38e-05184504f5cad8eb358898ae536cd7a7b37d3ce19528b801
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRH TP53INP1 ZNF467 RBM47

5.50e-05185504ff95a45b7cb782961bb8f008b6b507af2d4cb8b7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRACD TMEM130 LIMCH1 ZNF467

5.50e-05185504739260f8abebaf10a5cc49d91726278579e26170
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RA TRH APOBR WDFY4

5.50e-05185504ed7b26bdebfd0df2b4f5020a855a052d94ae7219
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A ATCAY CHGA CNGB1

5.50e-0518550494d0f283d63d932f310cc5a17ea893d71ba60f5e
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A ATCAY CHGA CNGB1

5.61e-0518650415f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCelldroplet-Pancreas|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D KIF1A CHGA RUNX1T1

5.73e-051875045f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM130 A1CF EFCC1 CHGA

5.85e-05188504e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D KIF1A CHGA PRRC2B

5.85e-05188504a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRACD ABR TRH WDFY4

5.97e-05189504287e59104687fe1665232c52993889f0f2c97f17
ToppCellwk_15-18-Epithelial-PNS-PCP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TMEM130 KIF1A ATCAY CHGA

5.97e-0518950422c927d2691b867fbdee1fbee042a6d3f7eadd7d
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRACD ABR TRH WDFY4

5.97e-051895046d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIF1A ATCAY CHGA CNGB1

5.97e-05189504de06ef69f3f97b3f21dc269eb6965da9b2f6e3f8
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRH TP53INP1 ZNF467 RBM47

6.10e-05190504992539c380576bf810c00a5f926cf1ee7d57dcf5
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CSF2RA RBM47 APOBR WDFY4

6.22e-05191504a5ee4d72b2311c8fa98ff73adc2499debb2014f1
ToppCellhuman_hepatoblastoma-Inflammatory_Monocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

ABR CSF2RA WDFY4 UST

6.22e-051915043b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

ABR CSF2RA RBM47 WDFY4

6.22e-051915049c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM130 ATCAY CHGA LMTK3

6.22e-05191504501d4f6ad389d9ac5051d4247b9bd3da96f713f9
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1D TRH LIMCH1 RUNX1T1

6.22e-05191504beb5bb42bd53bce01339da9110d374901548793c
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D KIF1A CHGA RUNX1T1

6.22e-05191504d48e5f67d384226add7d7fb2a124954136e09a82
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1D TRH LIMCH1 RUNX1T1

6.22e-051915046609d85fd2577633dcc067507304a6f9e5865ca3
ToppCellfacs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM130 ATCAY CHGA LMTK3

6.22e-051915048e06cc61eaff1796c2ce014074029408ba88d561
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

ABR CSF2RA RBM47 WDFY4

6.22e-05191504dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellfacs-Lung-EPCAM|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RA TRH RBM47 WDFY4

6.22e-0519150400957dd6077e107722835084d769e84eace0611f
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABR CSF2RA RBM47 WDFY4

6.35e-05192504bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A ATCAY CHGA CNGB1

6.35e-05192504d8f5df2c2a50e567f24ebecc8033ac97ba89d9c5
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A ATCAY CHGA CNGB1

6.35e-05192504307d64ef7add6a2778733e9945a1bd687feb6f44
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D LIMCH1 RUNX1T1 UST

6.35e-05192504deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A ATCAY CHGA CNGB1

6.48e-051935049661ea0ee7273928c7de2a9f49e853595fa77699
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D TRH LIMCH1 RUNX1T1

6.48e-05193504fa45042d30f9cfeed10e23270a78f18551219cfa
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

ABR CSF2RA RBM47 WDFY4

6.48e-05193504a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1D EFCC1 LIMCH1 RUNX1T1

6.48e-0519350499525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

ABR CSF2RA RBM47 WDFY4

6.48e-051935045fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1D CRACD LIMCH1 RUNX1T1

6.48e-05193504e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellwk_15-18-Epithelial-PNS|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIF1A ATCAY CHGA CNGB1

6.48e-05193504ca65f8f93058ad50d89e69e06c10deeb46dbfc87
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMEM130 ZC3H13 CHGA LMTK3

6.48e-05193504b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D TRH LIMCH1 RUNX1T1

6.48e-05193504ab511ea9e09216a965b3ae5a94f8c3c1ae33d944
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A ATCAY CHGA CNGB1

6.61e-0519450415224fb3e7ca5bd1fb8c41f8275842f737014095
ToppCelldroplet-Lung-LUNG-1m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRACD ABR TRH WDFY4

6.61e-05194504621e0e8fe77ff0be83ea9287ce46e97c47e2b3b9
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

TMEM130 KIF1A ATCAY CHGA

6.61e-05194504b6488bc3a8905e926ad298332963e1bbaf010046
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

TMEM130 KIF1A ATCAY CHGA

6.61e-051945041e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D LIMCH1 RUNX1T1 UST

6.61e-0519450489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

ABR CSF2RA RBM47 WDFY4

6.61e-05194504ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCelldroplet-Lung-1m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRACD ABR TRH WDFY4

6.61e-05194504d16ab5f0cfe73afe6c551fd3123d14784a082f56
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

ABR CSF2RA RBM47 WDFY4

6.74e-05195504c172c5599379c29123340621a36bfb1fc90c2115
ToppCellImmune-alveolar_macrophage_(MARCO_positive)|World / Lineage, Cell type, age group and donor

ABR CSF2RA RBM47 WDFY4

6.74e-05195504f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

ABR CSF2RA RBM47 WDFY4

6.74e-05195504148fff8c3c9ba45ec36e98dff1be57e3f8294506
DrugCeforanide [60925-61-3]; Down 200; 7.6uM; MCF7; HT_HG-U133A

ZNF219 KIF1A SPTBN1 KRBOX4 ZNF467 MKS1

3.34e-061914965351_DN
Diseasecarboxypeptidase B2 measurement

ZC3H13 DENR

1.11e-0410472EFO_0008069
DiseaseBradycardia

CACNA1D TRH

7.88e-0426472C0428977
DiseaseChild Development Disorders, Specific

KIF1A WDFY4

9.81e-0429472C0085997
DiseaseChild Development Deviations

KIF1A WDFY4

9.81e-0429472C0085996
DiseaseDevelopmental Disabilities

KIF1A WDFY4

1.05e-0330472C0008073
Diseaseautism spectrum disorder (implicated_via_orthology)

TAOK2 EIF4E1B DENR

1.84e-03152473DOID:0060041 (implicated_via_orthology)
DiseaseEndometrioma

ANO4 TRH UST

2.17e-03161473C0269102
DiseaseEndometriosis

ANO4 TRH UST

2.17e-03161473C0014175

Protein segments in the cluster

PeptideGeneStartEntry
TAEPKWDEEFEIELE

ABR

546

Q12979
DEEEVPEEWVLLHVV

C6orf120

31

Q7Z4R8
IAVDWAEPEVEVDED

A1CF

211

Q9NQ94
SWRAEPEEEQEEKED

ANKRD35

276

Q8N283
WEEEEEEIRPQFEAK

ANO4

461

Q32M45
EEEVEEERWQEEKKT

EFCC1

396

Q9HA90
IQVDWADPEKEVDEE

RBM46

216

Q8TBY0
IAVDWAEPEIDVDED

RBM47

226

A0AV96
AVERDTNVDEPVEWE

RASSF1

116

Q9NS23
VPEEIWKKAEEAVNE

RUNX1T1

441

Q06455
ENVDVKEEWQDEDLP

ATCAY

11

Q86WG3
TVDREAIWAEVEKEP

DOP1B

1061

Q9Y3R5
WEEEEKEEEAAERTP

EIF4E1B

16

A6NMX2
ERGTAPWVEEEEEEE

LMTK3

631

Q96Q04
VKQEVEKLEDEWERE

LCA5

401

Q86VQ0
EWEEKIQEQEEKIRE

GOLGA6L1

311

Q8N7Z2
EEKIWEQEEKIREQE

GOLGA6L1

591

Q8N7Z2
EKIWEQEEKIRDQEE

GOLGA6L2

511

Q8N9W4
EWEEKIQEQEEKIRE

GOLGA6L22

261

H0YM25
EEKIWEQEEKIREQE

GOLGA6L22

636

H0YM25
GQPVVERWISDEEDE

LRRC46

166

Q96FV0
VEWEEDVVDATPLEV

ANKS4B

336

Q8N8V4
EELKRQEEEEAEGWE

CRACD

356

Q6ZU35
WVEQEVEDRPEVKDE

ZNHIT6

96

Q9NWK9
DVIQEKWPEVDDDSI

DENR

176

O43583
EDRPEVWQVDEQIDH

KRBOX4

81

Q5JUW0
WITQAEDIDPENEEE

CACNA1D

441

Q01668
EVEDEIIWEEFTPEE

CSF2RA

371

P15509
WEFSEKDDEPEEVVV

ERCC6L

1001

Q2NKX8
VNEEEEEPEDEVQWT

KIF1A

686

Q12756
EEPEDEVQWTERECE

KIF1A

691

Q12756
EEWEKAQKEVEEEER

LIMCH1

801

Q9UPQ0
DEEVWGLPEEIEELR

TAOK2

836

Q9UL54
EEEEEELVTVVPKWK

RSPH1

196

Q8WYR4
EVDDLEQWIAEREVV

SPTBN1

1706

Q01082
WEQEEEEEEVRAREP

APOBR

176

Q0VD83
PGWQAKREEEEEEEE

CHGA

221

P10645
EEVAEEEAEKEPQDW

CNGB1

426

Q14028
EEPIDDEEQDDEKWL

UST

386

Q9Y2C2
VIPSEFWVEEEEEKQ

MKRN3

371

Q13064
HRPEEDEEEEIVIGW

MKS1

66

Q9NXB0
RDVEDEETWIREKEP

SPTAN1

791

Q13813
PEFNEKEDDEWILVD

TP53INP1

21

Q96A56
EREVKIEEVTPLWEE

WDFY4

2151

Q6ZS81
EEEEEVVKDGRPKWN

PRRC2B

391

Q5JSZ5
EQEEEPWVMEEEVLR

ZNF569

61

Q5MCW4
PKAQRSWEEEEEEEE

TRH

161

P20396
VKLKVVAEWEEVEPD

TMEM130

206

Q8N3G9
ECEEEELEPWQKKVE

ZNF280C

21

Q8ND82
EDRPEVWEVDEQIDH

ZNF674

81

Q2M3X9
PEEEEEVVEAEEETW

ZNF219

426

Q9P2Y4
EDQEAEEEVEWPQHL

ZNF467

101

Q7Z7K2
KERTPESEEENVEWE

ZC3H13

131

Q5T200