Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ZF_CCHC_HIVEP	HIVEP3 HIVEP1	9.15e-06	2	57	2	PS51811
Domain	CYCLIN	CCNB2 BRF2	6.00e-03	38	57	2	SM00385
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	POM121 CCNB2 POM121C	8.67e-05	36	34	3	M27245
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	POM121 CCNB2 POM121C	1.19e-04	40	34	3	MM14945
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	POM121 CCNB2 POM121C	2.77e-04	53	34	3	M27212
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	POM121 CCNB2 POM121C	3.09e-04	55	34	3	MM14917
Pathway	REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY	POM121 CCNB2 POM121C	5.77e-04	68	34	3	MM14921
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	USP36 ZNF106 NCOA6 TCF20 CCNB2 HMGXB4 DIDO1 KIF18B UBN2 POM121C DDX41 ZNF281 SAP130 SPTY2D1	3.98e-08	1294	61	14	30804502
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	USP36 ZNF106 MAP1B IGHG1 DIDO1 EIF3H SPATS2 KIF18B SPTY2D1	4.07e-08	410	61	9	26949251
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP36 TPRN RTL9 HMGXB4 TEKT1 LZTS2 PIP4K2C KIF18B POM121C DDX41 ZNF281 ANKRD52 SAP130	5.61e-08	1116	61	13	31753913
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	USP36 NCOA6 HIVEP1 TCF20 MAP1B HMGXB4 DIDO1 KIF18B UBN2 DDX41 ZNF281 SAP130	8.58e-08	954	61	12	36373674
Pubmed	Human transcription factor protein interaction networks.	NCOA6 HIVEP1 TCF20 NACA HMGXB4 GON4L DIDO1 VGLL4 EIF3H UBN2 POM121C ZNF281 SAP130	9.39e-07	1429	61	13	35140242
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	USP36 NCOA6 TCF20 NACA HMGXB4 DIDO1 PIP4K2C SAP130	1.70e-06	472	61	8	38943005
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	NCOA6 TCF20 DIDO1 POM121C DDX41 ZNF281 SAP130	2.27e-06	341	61	7	32971831
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	USP36 ZNF106 TCF20 UBN2 ZNF281 SPTY2D1	2.62e-06	222	61	6	37071664
Pubmed	Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing.	NDOR1 DIDO1	3.03e-06	2	61	2	35672775
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP36 NCOA6 GGA2 NACA DIDO1 PCDHA3 LZTS2 ZC3H7B	3.94e-06	529	61	8	14621295
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MAP1B NACA DIDO1 TACC2 EIF3H SPATS2 ZC3H7B SAP130 SPTY2D1	6.74e-06	759	61	9	35915203
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOA6 HIVEP1 TCF20 UBN2 ZNF281 SAP130	7.71e-06	268	61	6	33640491
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	HIVEP1 CCNB2 TPRN TACC2 LZTS2 PIP4K2C UBN2 ANKRD52	8.53e-06	588	61	8	38580884
Pubmed	Functional proteomics mapping of a human signaling pathway.	ZNF106 NCOA6 SEC24D HIVEP1 TPRN AFF1 LZTS2 SAP130	8.85e-06	591	61	8	15231748
Pubmed	POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.	POM121 POM121C	9.07e-06	3	61	2	30802453
Pubmed	Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.	POM121 POM121C	9.07e-06	3	61	2	35507432
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	USP36 NACA HMGXB4 GON4L DIDO1 EIF3H SPATS2 LZTS2 ZC3H7B UBN2 ZNF281 SPTY2D1	9.52e-06	1497	61	12	31527615
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	HIVEP1 TCF20 HMGXB4 DIDO1 KIF18B UBN2 DDX41 ZNF281	1.09e-05	608	61	8	36089195
Pubmed	EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3.	POM121 MAP1B STMN3 NACA POM121C	1.40e-05	174	61	5	35031058
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA6 TCF20 ZNF281 SAP130	1.42e-05	83	61	4	28794006
Pubmed	Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.	POM121 POM121C	1.81e-05	4	61	2	17900573
Pubmed	Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).	POM121 ZAN POM121C	3.23e-05	35	61	3	11013070
Pubmed	Interaction network of human early embryonic transcription factors.	NCOA6 HIVEP1 TCF20 UBN2 POM121C ZNF281	3.52e-05	351	61	6	38297188
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	USP36 DENND4A HIVEP1 HMGXB4 DIDO1 PKD1L2	4.12e-05	361	61	6	26167880
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TCF20 NHSL2 LZTS1 CNKSR3 DIDO1 SPATS2 PIP4K2C UBN2 CNTN1	4.40e-05	963	61	9	28671696
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA6 TCF20 MAP1B DIDO1 LZTS2 UBN2 SAP130	4.91e-05	549	61	7	38280479
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	ZNF106 HIVEP1 POM121C ZNF281	5.29e-05	116	61	4	30804394
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	GGA2 POM121 CCNB2 NACA EIF3H PIP4K2C POM121C DDX41 SPTY2D1	6.20e-05	1007	61	9	34597346
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	TCF20 MAP1B GON4L DIDO1 KIF18B DDX41	6.68e-05	394	61	6	27248496
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	ZNF106 TCF20 NACA ZC3H7B ZNF281	6.78e-05	242	61	5	34011540
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	TCF20 PCLO NACA DIDO1 ZNF281 SAP130	6.87e-05	396	61	6	26687479
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	MAP1B DIDO1 TACC2 ZNF281	8.25e-05	130	61	4	35545047
Pubmed	The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development.	NDOR1 IGHG1	8.42e-05	8	61	2	32601467
Pubmed	High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.	TACC2 LZTS2 ZNF281	9.49e-05	50	61	3	29560723
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	ESYT3 NCOA6 TCF20 PCLO NACA UBN2	1.01e-04	425	61	6	24999758
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	USP36 TCF20 MAP1B IGHG1 NACA PIP4K2C KIF18B DDX41 ZNF281 ANKRD52	1.14e-04	1353	61	10	29467282
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCOA6 HIVEP1 TCF20 LZTS1 POM121C ZNF281 ANKRD52	1.25e-04	638	61	7	31182584
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ZNF106 NCOA6 DENND4A HIVEP1 TCF20 MAP1B CNKSR3 DDX41	1.26e-04	861	61	8	36931259
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	RTL9 DIDO1 EIF3H ZC3H7B PKN3	1.37e-04	281	61	5	24163370
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	CCNB2 TPRN UBN2 SPTY2D1	1.51e-04	152	61	4	38360978
Pubmed	The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development.	LZTS1 LZTS2	1.65e-04	11	61	2	21949185
Pubmed	MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination.	NDOR1 IGHG1	1.65e-04	11	61	2	34586363
Pubmed	Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.	NDOR1 IGHG1	1.65e-04	11	61	2	29562201
Pubmed	A human MAP kinase interactome.	ZNF106 HIVEP1 POM121 TCF20 RAP1GAP2 POM121C	2.09e-04	486	61	6	20936779
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	USP36 MAP1B NACA DIDO1 TACC2 POM121C ZNF281 PKN3	2.20e-04	934	61	8	33916271
Pubmed	Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.	NCOA6 ZNF281	2.33e-04	13	61	2	17761849
Pubmed	Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.	ZNF106 HIVEP1 MAP1B	2.48e-04	69	61	3	32238831
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	USP36 MAP1B EIF3H SPATS2 KIF18B UBN2 ZNF281	2.71e-04	724	61	7	36232890
Pubmed	VGLL4 plays a critical role in heart valve development and homeostasis.	CCNB2 VGLL4	2.72e-04	14	61	2	30789911
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	POM121 POM121C	3.13e-04	15	61	2	14697343
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	USP36 ZNF106 TCF20 DIDO1 EIF3H KIF18B DDX41 SPTY2D1	3.22e-04	989	61	8	36424410
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ZNF106 NCOA6 HIVEP1 TCF20 AFF1 DIDO1 DDX41	4.04e-04	774	61	7	15302935
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SEC24D GGA2 CCNB2 RAP1GAP2 EIF3H SPATS2 LZTS2 ANKRD52	4.45e-04	1038	61	8	26673895
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	HIVEP3 KLF11 HIVEP1 TCF20 HMGXB4 DIDO1 EIF3H	5.22e-04	808	61	7	20412781
Pubmed	ATRX proximal protein associations boast roles beyond histone deposition.	ZNF106 KIF18B ZNF281	5.59e-04	91	61	3	34780483
Pubmed	The deubiquitinase USP36 promotes snoRNP group SUMOylation and is essential for ribosome biogenesis.	USP36 NDOR1	6.22e-04	21	61	2	33852194
Pubmed	Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions.	NDOR1 CNTN1	6.22e-04	21	61	2	23303943
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NCOA6 HIVEP1 TCF20 DIDO1 UBN2 DDX41 ZNF281 SAP130	6.63e-04	1103	61	8	34189442
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIVEP3 MSX2 NCOA6 NDOR1 RAP1GAP2 ZC3H7B POM121C PKN3	6.70e-04	1105	61	8	35748872
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	GGA2 RAP1GAP2 ZC3H7B	8.24e-04	104	61	3	10470851
Pubmed	Characterization of the zinc-induced Shank3 interactome of mouse synaptosome.	TCF20 ZAN NACA	9.44e-04	109	61	3	29111324
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOA6 POM121 AFF1 POM121C SAP130	9.51e-04	430	61	5	35044719
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DENND4A MAP1B NACA GON4L DIDO1 ZC3H7B	9.67e-04	650	61	6	38777146
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	MAP1B CCNB2 AFF1 EIF3H LZTS2 PIP4K2C DDX41	1.05e-03	910	61	7	36736316
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	ZNF106 MAP1B TACC2 UBN2 ZNF281	1.10e-03	444	61	5	34795231
Pubmed	TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.	SEC24D EIF3H	1.11e-03	28	61	2	29653964
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	POM121 TCF20 LZTS2 POM121C	1.19e-03	263	61	4	34702444
Pubmed	The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.	POM121 POM121C	1.19e-03	29	61	2	17577209
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	GGA2 GON4L DIDO1 TACC2 MSS51 SPATS2 LZTS2 PKN3	1.24e-03	1215	61	8	15146197
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	NCOA6 POM121 TCF20 POM121C SAP130	1.25e-03	457	61	5	32344865
Pubmed	Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.	MAP1B PCDHA3	1.28e-03	30	61	2	19054571
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	NCOA6 TCF20 POM121C	1.34e-03	123	61	3	26912792
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CCNB2 AFF1 DIDO1 SPATS2 LZTS2 ZNF281	1.36e-03	695	61	6	23602568
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	MSX2 KLF11 HIVEP1 TCF20 DIDO1 TACC2	1.51e-03	709	61	6	22988430
Pubmed	Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.	MAP1B IGHG1	1.54e-03	33	61	2	26025364
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	NCOA6 TCF20 DIDO1 ZNF281	1.56e-03	283	61	4	30585729
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	DENND4A GGA2 AFF1 TACC2	1.60e-03	285	61	4	34369648
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	TCF20 HMGXB4 DIDO1	1.71e-03	134	61	3	25452129
Pubmed	Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.	SMIM8 RAP1GAP2 LZTS2	1.71e-03	134	61	3	24324551
Interaction	ASF1A interactions	NCOA6 HIVEP1 TCF20 KIF18B UBN2 ZNF281 SAP130 SPTY2D1 BRF2	5.76e-08	249	61	9	int:ASF1A
Interaction	SNRNP40 interactions	USP36 HIVEP1 POM121 TCF20 GON4L UBN2 POM121C DDX41 ZNF281 SPTY2D1	1.95e-05	637	61	10	int:SNRNP40
Interaction	MKI67 interactions	USP36 ZNF106 NCOA6 MAP1B IGHG1 DIDO1 EIF3H SPATS2 KIF18B SPTY2D1	2.26e-05	648	61	10	int:MKI67
Interaction	TBXT interactions	NCOA6 HIVEP1 TCF20 ZNF281 SAP130	2.67e-05	116	61	5	int:TBXT
Interaction	SMC5 interactions	USP36 NCOA6 HIVEP1 TCF20 MAP1B HMGXB4 DIDO1 KIF18B UBN2 DDX41 ZNF281 SAP130	3.82e-05	1000	61	12	int:SMC5
Interaction	SLX4 interactions	USP36 ZNF106 TCF20 IGHG1 NACA DIDO1 UBN2 ZNF281 SPTY2D1	5.22e-05	572	61	9	int:SLX4
Interaction	ZNF330 interactions	USP36 ZNF106 TCF20 HMGXB4 KIF18B DDX41 ZNF281 SPTY2D1	5.70e-05	446	61	8	int:ZNF330
Interaction	PPIA interactions	USP36 NCOA6 TCF20 MAP1B NACA HMGXB4 DIDO1 VGLL4 PIP4K2C SAP130 PKN3	6.34e-05	888	61	11	int:PPIA
Interaction	NUP43 interactions	USP36 NCOA6 HIVEP1 POM121 TCF20 GON4L UBN2 POM121C ZNF281	1.03e-04	625	61	9	int:NUP43
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	NACA SPATS2 PIP4K2C ANKRD52 NCKAP1L	2.52e-04	423	61	5	chr12q13
Cytoband	12q13.3	PIP4K2C ANKRD52	2.12e-03	51	61	2	12q13.3
GeneFamily	Leucine zipper tumor suppressor family	LZTS1 LZTS2	2.57e-05	4	38	2	1314
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND4A HIVEP1 MAP1B AFF1 SPTY2D1	5.50e-06	185	61	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B PCLO RAP1GAP2 TACC2 UBN2	6.58e-06	192	61	5	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	MAP1B PCLO NACA HMGXB4 EIF3H	6.92e-06	194	61	5	4903a0d6e36599bcb83b179462e5b949df9eb685
ToppCell	Basal-basal-5\|World / Class top	CCNB2 NACA EIF3H PKN3 CNTN1	7.46e-06	197	61	5	267db5fc5d59eeadbc7746af08ed6e3cb3da8f3a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D IGHG1 SPATS2 NCKAP1L	8.10e-05	167	61	4	0130743084dbcb20e10f96715d30961122150cbf
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D IGHG1 SPATS2 NCKAP1L	8.10e-05	167	61	4	7bcae3797d3a0811e7f39885afdfd29ec517f11b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D IGHG1 SPATS2 NCKAP1L	8.10e-05	167	61	4	c6f0209a1ad797631fdfa3efab6db6b1d3e8e315
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND4A PCLO RAP1GAP2 AFF1	9.50e-05	174	61	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	Club-club-15\|World / Class top	CCNB2 RAP1GAP2 KIF18B PKN3	9.71e-05	175	61	4	ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCell	10x5'-blood-Lymphocytic_B_plasma-Plasmablasts\|blood / Manually curated celltypes from each tissue	IGHG1 CCNB2 SPATS2 KIF18B	9.71e-05	175	61	4	2e048bf7961c3d86b6e12a1ebae3b3f2359af457
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ESYT3 CCNB2 KIF18B ANKRD52	9.92e-05	176	61	4	581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasmablasts\|Liver / Manually curated celltypes from each tissue	IGHG1 CCNB2 SPATS2 KIF18B	1.01e-04	177	61	4	1d88ae316d65ca5fdc736c9da93885b6b40c32bb
ToppCell	ILEUM-non-inflamed-(5)_Plasmablasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SEC24D IGHG1 CCNB2 SPATS2	1.06e-04	179	61	4	58c8996120637315dcbd1991a71516c09173051e
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP1B LZTS1 TACC2 KIF18B	1.08e-04	180	61	4	67c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D IGHG1 SPATS2 NCKAP1L	1.11e-04	181	61	4	6cdee2f56bc633b387b4dbbd78c624edbd712c24
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D IGHG1 SPATS2 NCKAP1L	1.11e-04	181	61	4	5a4fe0eca7cbc9cbc8a2fdbe795a7c5f4052a659
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEC24D IGHG1 SPATS2 NCKAP1L	1.11e-04	181	61	4	b75b8b025257bccfe661fd0f92ab284b2a9c12ee
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN PCLO PKD1L2 CNTN1	1.18e-04	184	61	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN PCLO PKD1L2 CNTN1	1.18e-04	184	61	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZAN PCLO PKD1L2 CNTN1	1.18e-04	184	61	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POM121 PCLO RAP1GAP2 ANKRD52	1.20e-04	185	61	4	d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCell	IPF-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	IGHG1 CCNB2 SPATS2 KIF18B	1.23e-04	186	61	4	f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MAP1B STMN3 PCLO RAP1GAP2	1.23e-04	186	61	4	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM74B MAP1B LZTS1 PCDHA3	1.23e-04	186	61	4	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	P15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DENND4A MAP1B NHSL2 PKN3	1.28e-04	188	61	4	50b27fc12347ca16bd62333baf345c83cb422a8f
ToppCell	control-Lymphocytic-Plasmablast\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SEC24D IGHG1 CCNB2 SPATS2	1.31e-04	189	61	4	2e4c2618d06120f83cb4887dd3497b81984a8607
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B PCLO RAP1GAP2 UBN2	1.36e-04	191	61	4	fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCell	droplet-Pancreas-Endocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B PCLO RAP1GAP2 UBN2	1.39e-04	192	61	4	4510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCell	COVID-19_Severe-Plasmablast\|World / disease group, cell group and cell class	SEC24D IGHG1 CCNB2 SPATS2	1.39e-04	192	61	4	a333053fe2bd206c32790916bfc5fce904ab7f57
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B PCLO RAP1GAP2 TACC2	1.44e-04	194	61	4	92b39a935e8c577eb1123d706d168fa13cf3344c
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts\|lymph-node_spleen / Manually curated celltypes from each tissue	IGHG1 CCNB2 SPATS2 KIF18B	1.47e-04	195	61	4	1390728b9a514db534e8bc6dcf72cf51a1065780
ToppCell	(08)_PNEC\|World / shred by cell type and Timepoint	MAP1B STMN3 PCLO RAP1GAP2	1.50e-04	196	61	4	2ee37155c03cd5009427a4bffe6c80ed2ac6939e
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SEC24D IGHG1 CCNB2 SPATS2	1.53e-04	197	61	4	6fe013f98c64b3c5a4e61002254717fb411f8e59
ToppCell	MS-cycling\|MS / Condition, Cell_class and T cell subcluster	IGHG1 CCNB2 SPATS2 KIF18B	1.56e-04	198	61	4	0c22f2cc0e5ca91cabcd4aac2b9ef05af47e967f
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-B-Plasmablast\|Multiple_Sclerosis / Disease, condition lineage and cell class	SEC24D IGHG1 CCNB2 SPATS2	1.56e-04	198	61	4	c30b71b998acde080adb90a2016a165c5ed17a81
ToppCell	MS-cycling-\|MS / Condition, Cell_class and T cell subcluster	IGHG1 CCNB2 SPATS2 KIF18B	1.56e-04	198	61	4	19c5d6b65de490118574b1f86b45c58b3a51df7f
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	POM121 MAP1B POM121C DDX41	1.59e-04	199	61	4	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	Control-Control-Lymphocyte-B-Plasmablast\|Control / Disease, condition lineage and cell class	SEC24D IGHG1 CCNB2 SPATS2	1.59e-04	199	61	4	c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	ZNF106 MAP1B PCLO ZNF281	1.59e-04	199	61	4	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-CD4+_T_naive\|Multiple_Sclerosis / Disease, condition lineage and cell class	NHSL2 STMN3 NACA EIF3H	1.62e-04	200	61	4	c1a0adaf2e4b099434557272f204cd36d6d84819
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	HIVEP3 MAP1B PCLO UBN2	1.62e-04	200	61	4	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Tracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM74B MAP1B NHSL2 LZTS1	1.62e-04	200	61	4	9d3ae9ea47b1017adb63aa02d10e98193d478458
ToppCell	Tracheal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM74B MAP1B NHSL2 LZTS1	1.62e-04	200	61	4	78cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal\|2m / Sample Type, Dataset, Time_group, and Cell type.	MAP1B STMN3 PCLO CNTN1	1.62e-04	200	61	4	60b86c4a4e247b2673d31b085b440a6e574393bb
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Cortical_neuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	MAP1B STMN3 PCLO CNTN1	1.62e-04	200	61	4	db2dbd31dd02c0d1c1070ed5548ce949227e4775
Disease	testosterone measurement	NCOA6 DENND4A LIPE ZAN NHSL2 TPRN CNKSR3 RTL9 AFF1 PKN3	1.48e-04	1275	57	10	EFO_0004908
Disease	sphingomyelin 18:1 measurement	MAP1B LZTS1	2.82e-04	13	57	2	EFO_0010394
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP3 HIVEP1	2.82e-04	13	57	2	DOID:0050787 (implicated_via_orthology)
Disease	vital capacity	ZNF106 NCOA6 TCF20 LZTS1 PCLO RTL9 AFF1 PCDHA3 EIF3H	5.66e-04	1236	57	9	EFO_0004312
Disease	neuroimaging measurement	MSX2 ZNF106 MAP1B CNKSR3 AFF1 TACC2 KIF18B POM121C	9.89e-04	1069	57	8	EFO_0004346
Disease	neurotic disorder	HIVEP1 PCLO ZC3H7B	9.96e-04	101	57	3	EFO_0004257
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	ZNF106 TCF20 AFF1	1.05e-03	103	57	3	EFO_0008595, EFO_0020944
Disease	conotruncal heart malformations	HIVEP1 MAP1B EIF3H	1.41e-03	114	57	3	MONDO_0016581
Disease	1,5 anhydroglucitol measurement	PCDHA3 PKD1L2	1.44e-03	29	57	2	EFO_0008009
Disease	granulocyte colony-stimulating factor measurement	MAP1B VGLL4	1.98e-03	34	57	2	EFO_0008142
Disease	language measurement	TCF20 RAP1GAP2 GON4L	2.24e-03	134	57	3	EFO_0007797
Disease	non-high density lipoprotein cholesterol measurement	HIVEP1 POM121 HMGXB4 AFF1 SPTY2D1 PKN3	2.48e-03	713	57	6	EFO_0005689
Disease	PR interval	HIVEP3 CNKSR3 SMIM8 RAP1GAP2 AFF1	2.66e-03	495	57	5	EFO_0004462
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	ZNF106 IGHG1 AFF1	2.75e-03	144	57	3	EFO_0004611, EFO_0020943
Disease	response to methotrexate, serum alanine aminotransferase measurement	LZTS1 RAP1GAP2	3.15e-03	43	57	2	EFO_0004735, GO_0031427
Disease	low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	ZNF106 IGHG1 AFF1	3.26e-03	153	57	3	EFO_0004611, EFO_0020946
Disease	congenital left-sided heart lesions	HIVEP3 PKD1L2	3.91e-03	48	57	2	EFO_0005938
Disease	cognitive inhibition measurement	TCF20 RAP1GAP2	4.23e-03	50	57	2	EFO_0007969
Disease	Malignant neoplasm of breast	NCOA6 LIPE STPG1 AFF1 TACC2 LZTS2 ZNF281	4.49e-03	1074	57	7	C0006142
Disease	Alzheimer's disease (implicated_via_orthology)	HIVEP3 HIVEP1	5.47e-03	57	57	2	DOID:10652 (implicated_via_orthology)
Disease	neutrophil-to-lymphocyte ratio	HIVEP1 RAP1GAP2 ZC3H7B	5.53e-03	185	57	3	EFO_0008447

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKSPRPMKCPASPFA	ESYT3	701	A0FGR9
LDKLMPSHSPPTPVK	C6orf136	276	Q5SQH8
LSKLFKPPQPPARMD	EIF3H	301	O15372
STMKPFPPKDAVSPF	ANKRD52	1016	Q8NB46
KLPSKSSSPNSPLPM	DENND4A	721	Q7Z401
IPPPMAIIAPLFAKS	RRH	271	O14718
KTDLMAFSPSLPPCP	PCDHA3	766	Q9Y5H8
PMSISPPDFSPKTAK	MAP1B	1616	P46821
VLPKPRGAPSLPSFM	LZTS2	151	Q9BRK4
VDFDPSTPPKLMPFS	LZTS1	96	Q9Y250
KKPPSSVAPIIMAPT	MSS51	11	Q4VC12
DIRKMPPAPSGPKAS	PCLO	1121	Q9Y6V0
SKPPFLLEKSMEPSL	NCKAP1L	41	P55160
SSKLPAFSPLMPPAV	GGA2	551	Q9UJY4
LSPQKKSPPTTMLLP	HMGXB4	496	Q9UGU5
KSPPTTMLLPASPAK	HMGXB4	501	Q9UGU5
IPPPIKSFKEMKFPA	DDX41	176	Q9UJV9
PVPLFTMKGPKPTSS	KIF18B	761	Q86Y91
EPPSESKPFLAPMIS	NDOR1	201	Q9UHB4
PVDIKIMSFPKSPFP	PKD1L2	1111	Q7Z442
ASPMFKPIFTAPPKS	POM121C	701	A8CG34
SKTPTPPAPTLLKMT	NCOA6	1876	Q14686
PMFKPIFTAPPKSEK	POM121	726	Q96HA1
VQMEKLAPKGPSPTP	CCNB2	81	O95067
PPSDMIEAFTKKAPP	CNTN1	891	Q12860
PVPKVMLPSLAPSKF	GON4L	1096	Q3T8J9
MSPPPKSSLPKAELF	DIDO1	1521	Q9BTC0
PASPALLLPPCMLKS	BRF2	351	Q9HAW0
SSMLPAFLKPPPQLS	KLF11	296	O14901
PSVFLFPPKPKDTLM	IGHG1	121	P01857
FPPKPKDTLMISRTP	IGHG1	126	P01857
SPLLAPDSMLKSLPP	LIPE	971	Q05469
FLPKKTPLGEEMTPP	PKN3	496	Q6P5Z2
PPPVMLLPDDFKASS	PIP4K2C	66	Q8TBX8
AAKPMLPSSFSLPFP	MSX2	211	P35548
AKPPPKEVPSFGMLT	RTL9	1131	Q8NET4
PSSPEICPNKEKPFM	RAP1GAP2	611	Q684P5
RKSSLPPTSPMEKFP	NHSL2	751	Q5HYW2
PPTSPMEKFPKSRLS	NHSL2	756	Q5HYW2
MAKLLQPPPKFLPSE	TEKT1	1	Q969V4
PKVPLKSAPPPMNFT	SPTY2D1	156	Q68D10
CRKSKPPNPPAFIFM	SEC24D	431	O94855
PESPMLSSPPKKKDT	STMN3	66	Q9NZ72
SSQSSKKEMLPPPPV	AFF1	856	P51825
KKEMLPPPPVSSSSQ	AFF1	861	P51825
EKTPSYGKPRPLSMP	CNK3/IPCEF1	421	G9CGD6
EKTPSYGKPRPLSMP	CNKSR3	421	Q6P9H4
TGPPPISPSKRKFSM	VGLL4	46	Q14135
SMEPSPPTPSFKKGL	SPATS2	516	Q86XZ4
PSFPMASPPGLELKT	TMEM74B	21	Q9NUR3
FSMAASPKLAASPKP	UBN2	1031	Q6ZU65
MPTADPKPPASLKST	SRRM5	21	B3KS81
LPSFMKALKFETPAP	STPG1	136	Q5TH74
AVPLSFSEGLMKPPP	SAP130	131	Q9H0E3
MPTSDLPPGASPRKK	SAP130	821	Q9H0E3
KAEAPSPSSDMRPKP	HIVEP3	956	Q5T1R4
SVLPSSLPKPPFGML	ZNF281	726	Q9Y2X9
MSSAPEPPTFKKEPP	SMIM8	1	Q96KF7
GPSMLPSVPKKDAPR	TACC2	1826	O95359
ATLPKNPPPKRATEM	TCF20	1731	Q9UGU0
FMVIPKSKASGAPPP	TPRN	331	Q4KMQ1
KMPSLKSPLLPCPAT	ZNF106	446	Q9H2Y7
SPLRTDSPKAMDPKP	HIVEP1	571	P15822
EPASTMSPPPAKKLA	USP36	676	Q9P275
LPPASFGLVMDPSKK	ZC3H7B	316	Q9UGR2
STEKPSIPMEKPTLP	ZAN	811	Q9Y493
KKAPATPAPMGAPTL	NACA	1491	E9PAV3
EALIPPAMTVPSPKK	NACA	1546	E9PAV3