Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN3B GRIN1 GRIN2C

4.80e-0581933GO:0004972
GeneOntologyMolecularFunctiontransferrin receptor activity

TFR2 TFRC

9.29e-0521932GO:0004998
GeneOntologyMolecularFunctionrecombination hotspot binding

PRDM9 PRDM7

9.29e-0521932GO:0010844
GeneOntologyMolecularFunctiontransporter activity

ABCA13 PEX6 SLC22A7 NDUFV1 SLC8B1 KCNB1 CLCN7 SLC35A4 PGRMC2 SCN4B SLC16A11 SLC35E3 SLC5A12 GRIN3B SLC25A48 SLC39A7 GRIN1 GRIN2C CPOX TFRC SEC61A2 CNNM3 IGF1R SLC49A4 SLC13A5 NALF2 MFSD5

1.22e-04128919327GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCA13 SLC22A7 NDUFV1 SLC8B1 KCNB1 CLCN7 SLC35A4 PGRMC2 SCN4B SLC16A11 SLC35E3 SLC5A12 GRIN3B SLC25A48 SLC39A7 GRIN1 GRIN2C CPOX TFRC SEC61A2 CNNM3 SLC49A4 SLC13A5 NALF2 MFSD5

1.86e-04118019325GO:0022857
GeneOntologyMolecularFunctionstarch binding

EPM2A STBD1

2.77e-0431932GO:2001070
GeneOntologyCellularComponentexcitatory synapse

SORT1 NRXN1 SNAP91 BSN CBLN3 GRIN1 UNC13A

5.94e-051071927GO:0060076
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN3B GRIN1 GRIN2C

6.15e-0591923GO:0017146
GeneOntologyCellularComponentinhibitory synapse

GAD2 LHFPL4 NRXN1 BSN

1.79e-04311924GO:0060077
GeneOntologyCellularComponentcell surface

HYAL4 IGSF5 IZUMO1R ADAM10 DSCAML1 SORT1 KCNB1 NRXN1 SCART1 BSN MPL NID2 GRIN1 TFR2 TFRC CD93 ARSA ARSB CLEC14A CSPG5 FOLH1B MUC1 AGRN

2.31e-04111119223GO:0009986
GeneOntologyCellularComponentcollagen-containing extracellular matrix

EMID1 ADAM10 SSPOP SEMA3B CMA1 NID2 COL11A2 COL15A1 LMAN1L CLEC14A MMRN2 NGLY1 MUC1 AGRN

4.06e-0453019214GO:0062023
GeneOntologyCellularComponentcytoplasmic vesicle membrane

GAD2 MLEC ABCA13 INPP5B ARHGAP26 ADAM10 SORT1 SNAP91 NBEAL2 HYAL3 C3AR1 BSN BAIAP3 STBD1 SCAMP2 GRIN1 RAB11FIP1 TFRC CD93 MOXD1 CSPG5 RAB11FIP4 UNC13A AHNAK2

9.37e-04130719224GO:0030659
GeneOntologyCellularComponentsynaptic membrane

GAD2 LHFPL4 DDN ADAM10 KCNB1 NRXN1 SNAP91 GRIN3B BSN GRIN1 GRIN2C CSPG5 SORCS3 UNC13A

1.03e-0358319214GO:0097060
GeneOntologyCellularComponentextracellular matrix

EMID1 ADAM10 SSPOP SEMA3B CMA1 NID2 COL11A2 COL15A1 LMAN1L CLEC14A MMRN2 HSD17B12 NGLY1 MUC1 AGRN

1.12e-0365619215GO:0031012
GeneOntologyCellularComponentvesicle membrane

GAD2 MLEC ABCA13 INPP5B ARHGAP26 ADAM10 SORT1 SNAP91 NBEAL2 HYAL3 C3AR1 BSN BAIAP3 STBD1 SCAMP2 GRIN1 RAB11FIP1 TFRC CD93 MOXD1 CSPG5 RAB11FIP4 UNC13A AHNAK2

1.13e-03132519224GO:0012506
GeneOntologyCellularComponentexternal encapsulating structure

EMID1 ADAM10 SSPOP SEMA3B CMA1 NID2 COL11A2 COL15A1 LMAN1L CLEC14A MMRN2 HSD17B12 NGLY1 MUC1 AGRN

1.15e-0365819215GO:0030312
MousePhenohippocampal neuron degeneration

NHLRC1 CLCN7 EPM2A FOLH1B MRPL3

3.90e-06221585MP:0000811
DomainTFR_dimer

TFR2 TFRC FOLH1B

1.96e-0561883PF04253
Domain-

TFR2 TFRC FOLH1B

1.96e-05618831.20.930.40
DomainTFR-like_dimer_dom

TFR2 TFRC FOLH1B

3.41e-0571883IPR007365
DomainLamG

NRXN1 COL11A2 COL15A1 CELSR2 AGRN

7.74e-05441885SM00282
DomainPeptidase_M28

TFR2 TFRC FOLH1B

2.07e-04121883PF04389
DomainPeptidase_M28

TFR2 TFRC FOLH1B

2.07e-04121883IPR007484
DomainLaminin_G

NRXN1 COL11A2 COL15A1 CELSR2 AGRN

2.91e-04581885IPR001791
DomainCBM_20

EPM2A STBD1

3.00e-0431882PF00686
DomainCBM_2

EPM2A STBD1

3.00e-0431882SM01065
DomainCBM20

EPM2A STBD1

3.00e-0431882PS51166
DomainCBM_fam20

EPM2A STBD1

3.00e-0431882IPR002044
DomainEGF_2

HYAL4 SSPOP NRXN1 HYAL3 NID2 CD93 CELSR2 CLEC14A CSPG5 AGRN

3.65e-0426518810PS01186
Domain-

TMPRSS6 MUC1 AGRN

4.18e-041518833.30.70.960
DomainEMI

EMID1 SSPOP MMRN2

6.15e-04171883PS51041
DomainPeripla_BP_I

GRIN3B NPR3 GRIN1 GRIN2C

6.21e-04391884IPR028082
DomainEGF

HYAL4 NRXN1 HYAL3 NID2 CD93 CELSR2 CLEC14A CSPG5 AGRN

6.44e-042351889SM00181
DomainEGF_3

SSPOP NRXN1 HYAL3 NID2 CD93 CELSR2 CLEC14A CSPG5 AGRN

6.44e-042351889PS50026
DomainLig_chan-Glu_bd

GRIN3B GRIN1 GRIN2C

7.33e-04181883PF10613
DomainGlu/Gly-bd

GRIN3B GRIN1 GRIN2C

7.33e-04181883IPR019594
DomainLig_chan-Glu_bd

GRIN3B GRIN1 GRIN2C

7.33e-04181883SM00918
DomainIontro_rcpt

GRIN3B GRIN1 GRIN2C

7.33e-04181883IPR001320
DomainIono_rcpt_met

GRIN3B GRIN1 GRIN2C

7.33e-04181883IPR001508
DomainLig_chan

GRIN3B GRIN1 GRIN2C

7.33e-04181883PF00060
DomainPBPe

GRIN3B GRIN1 GRIN2C

7.33e-04181883SM00079
DomainMunc13_dom-2

BAIAP3 UNC13A

9.88e-0451882IPR014772
DomainNUT

NUTM2A NUTM2B

9.88e-0451882IPR024310
DomainNUT_N

NUTM2A NUTM2B

9.88e-0451882IPR024309
DomainMHD2

BAIAP3 UNC13A

9.88e-0451882PS51259
DomainMunc13_subgr_dom-2

BAIAP3 UNC13A

9.88e-0451882IPR019558
DomainNUT

NUTM2A NUTM2B

9.88e-0451882PF12881
DomainSortilin_C

SORT1 SORCS3

9.88e-0451882PF15901
DomainSortilin-Vps10

SORT1 SORCS3

9.88e-0451882PF15902
DomainVPS10

SORT1 SORCS3

9.88e-0451882IPR006581
DomainSortilin_N

SORT1 SORCS3

9.88e-0451882IPR031778
DomainSortilin_C

SORT1 SORCS3

9.88e-0451882IPR031777
DomainMembr_traf_MHD

BAIAP3 UNC13A

9.88e-0451882PF10540
DomainVPS10

SORT1 SORCS3

9.88e-0451882SM00602
DomainHyaluronidase

HYAL4 HYAL3

9.88e-0451882IPR018155
DomainGlyco_hydro_56

HYAL4 HYAL3

9.88e-0451882PF01630
DomainSEA

TMPRSS6 MUC1 AGRN

1.34e-03221883PF01390
DomainRBD-FIP

RAB11FIP1 RAB11FIP4

1.47e-0361882PF09457
DomainDUF3669_Znf

ZNF212 ZNF746

1.47e-0361882IPR022137
DomainDUF3669

ZNF212 ZNF746

1.47e-0361882PF12417
DomainRab-bd_FIP-RBD

RAB11FIP1 RAB11FIP4

1.47e-0361882IPR019018
DomainFIP_RBD

RAB11FIP1 RAB11FIP4

1.47e-0361882PS51511
DomainSEA

TMPRSS6 MUC1 AGRN

1.53e-03231883PS50024
DomainSEA_dom

TMPRSS6 MUC1 AGRN

1.53e-03231883IPR000082
DomainHormR

ADGRB2 VIPR1 CELSR2

1.96e-03251883SM00008
DomainMunc13_1

BAIAP3 UNC13A

2.05e-0371882IPR014770
DomainMHD1

BAIAP3 UNC13A

2.05e-0371882PS51258
DomainDUF1041

BAIAP3 UNC13A

2.05e-0371882PF06292
DomainCAPS_dom

BAIAP3 UNC13A

2.05e-0371882IPR010439
Domain-

INPP5B SMPD3 SMPD2

2.20e-032618833.60.10.10
DomainExo_endo_phos

INPP5B SMPD3 SMPD2

2.20e-03261883PF03372
PathwayWP_NRXN1_DELETION_SYNDROME

NRXN1 GRIN3B GRIN1 GRIN2C

1.80e-05181284M48098
PathwayKEGG_MEDICUS_REFERENCE_DERMATAN_SULFATE_DEGRADATION

HYAL4 HYAL3 ARSB

3.96e-0581283M47607
PathwayREACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM

B4GALT7 HYAL3 ARSB CSPG5 AGRN

7.15e-05481285MM14696
PathwayREACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM

B4GALT7 HYAL3 ARSB CSPG5 AGRN

8.72e-05501285M678
PathwayREACTOME_CS_DS_DEGRADATION

HYAL3 ARSB CSPG5

1.96e-04131283MM14805
PathwayREACTOME_GLYCOSPHINGOLIPID_CATABOLISM

SMPD3 ARSA ARSB SMPD2

2.44e-04341284MM17076
PathwayREACTOME_CS_DS_DEGRADATION

HYAL3 ARSB CSPG5

2.47e-04141283M651
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 ARHGAP26 EMID1 ADGRB2 PEX6 PRAG1 FASN SLC8B1 CLCN7 NBEAL2 LRRC56 CPVL TEX19 FLNA FLNC SHROOM3 KIFC2 WDR59 IGF1R ARAP3 CELSR2 HELZ2 AGRN MFSD5 AHNAK2 HR

6.81e-1011051942635748872
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

VWA5B2 MZB1 ZNF862 PLK5 LMTK3 MRGPRG ACOT2 BSN TSGA10IP TET3 SLC39A7 PRDM7

8.83e-092331941237704626
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SMG1 DSCAML1 CEP68 NRXN1 WDR35 BAIAP3 TTC28 TRIOBP ALS2 HELZ2

6.13e-072251941012168954
Pubmed

Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.

CD93 CLEC14A MMRN2

6.81e-074194328671670
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

B4GALT7 MLEC ADAM10 SORT1 SIAE HYAL3 JMJD8 SEMA3B CPVL SLC39A7 NPR3 COL15A1 GXYLT1 TFRC CNNM3 IGF1R ARSA CELSR2 LTBR NGLY1 AGRN MFSD5

1.12e-0612011942235696571
Pubmed

Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure.

KCNB1 GRIN3B GRIN1 GRIN2C

2.11e-0617194424086760
Pubmed

The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.

SMPD3 GRIN3B GRIN1 GRIN2C

5.22e-0621194422114277
Pubmed

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.

GRIN3B GRIN1 GRIN2C

5.88e-067194322940423
Pubmed

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

GRIN3B GRIN1 GRIN2C

5.88e-067194322833210
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

ADAM10 SSPOP NID2 COL11A2 COL15A1 NGLY1 MUC1 AGRN

6.80e-06175194828071719
Pubmed

HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.

GRIN3B GRIN1 GRIN2C

9.38e-06819438563977
Pubmed

Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.

GRIN3B GRIN1 GRIN2C

9.38e-06819437695237
Pubmed

Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.

GRIN3B GRIN1 GRIN2C

9.38e-06819438724036
Pubmed

Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.

GRIN3B GRIN1 GRIN2C

9.38e-06819438822372
Pubmed

Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.

GRIN3B GRIN1 GRIN2C

9.38e-068194310448428
Pubmed

Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.

GRIN3B GRIN1 GRIN2C

9.38e-06819438955056
Pubmed

Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.

GRIN3B GRIN1 GRIN2C

9.38e-068194310555109
Pubmed

Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons.

GRIN3B GRIN1 GRIN2C

9.38e-06819438804048
Pubmed

The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid.

GRIN3B GRIN1 GRIN2C

9.38e-06819438845955
Pubmed

HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures.

GRIN3B GRIN1 GRIN2C

9.38e-06819438821747
Pubmed

Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.

FASN FLNA FLNC NPR3 SHROOM3

1.18e-0553194515306695
Pubmed

Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS.

GRIN3B GRIN1 GRIN2C

1.40e-059194321491143
Pubmed

D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.

GRIN3B GRIN1 GRIN2C

1.40e-059194322552781
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

MLEC CADM4 ARHGAP26 ADGRB2 NDUFV1 NRXN1 SCN4B SMPD3 CNNM3 CSPG5 FAM131B

1.91e-054051941138187761
Pubmed

N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.

GRIN3B GRIN1 GRIN2C

1.99e-0510194319332541
Pubmed

Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.

BRCA2 SLC39A7 TMPRSS6 TFR2 TFRC IGF1R

2.28e-05101194620587610
Pubmed

HIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.

GRIN3B GRIN1 GRIN2C

2.73e-0511194324739951
Pubmed

Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase.

GRIN3B GRIN1 GRIN2C

2.73e-051119438581564
Pubmed

Effects of SDF-1alpha and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells.

GRIN3B GRIN1 GRIN2C

2.73e-0511194316481105
Pubmed

Laforin and malin deletions in mice produce similar neurologic impairments.

NHLRC1 EPM2A

3.10e-052194222487859
Pubmed

Lafora Disease Is an Inherited Metabolic Cardiomyopathy.

NHLRC1 EPM2A

3.10e-052194228619201
Pubmed

Engagement of transferrin receptor by polymeric IgA1: evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy.

TFR2 TFRC

3.10e-052194215987753
Pubmed

Loss of malin, but not laforin, results in compromised autophagic flux and proteasomal dysfunction in cells exposed to heat shock.

NHLRC1 EPM2A

3.10e-052194227975203
Pubmed

LIGHT/LTβR signaling regulates self-renewal and differentiation of hematopoietic and leukemia stem cells.

TNFSF14 LTBR

3.10e-052194233594067
Pubmed

Dissecting the CD93-Multimerin 2 interaction involved in cell adhesion and migration of the activated endothelium.

CD93 MMRN2

3.10e-052194228912033
Pubmed

A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells.

TFR2 TFRC

3.10e-052194221849092
Pubmed

LIGHT (TNFSF14) enhances osteogenesis of human bone marrow-derived mesenchymal stem cells.

TNFSF14 LTBR

3.10e-052194233606781
Pubmed

Increased laforin and laforin binding to glycogen underlie Lafora body formation in malin-deficient Lafora disease.

NHLRC1 EPM2A

3.10e-052194222669944
Pubmed

Cutting edge: selective blockade of LIGHT-lymphotoxin beta receptor signaling protects mice from experimental cerebral malaria caused by Plasmodium berghei ANKA.

TNFSF14 LTBR

3.10e-052194219017933
Pubmed

Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease.

NHLRC1 EPM2A

3.10e-052194226648032
Pubmed

The sulfatase gene family: cross-species PCR cloning using the MOPAC technique.

ARSA ARSB

3.10e-05219421572648
Pubmed

A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency.

ARSA ARSB

3.10e-05219427628016
Pubmed

Lafora progressive myoclonus epilepsy: NHLRC1 mutations affect glycogen metabolism.

NHLRC1 EPM2A

3.10e-052194221505799
Pubmed

Deciphering the role of malin in the lafora progressive myoclonus epilepsy.

NHLRC1 EPM2A

3.10e-052194222815132
Pubmed

Hyperphosphorylation of glucosyl C6 carbons and altered structure of glycogen in the neurodegenerative epilepsy Lafora disease.

NHLRC1 EPM2A

3.10e-052194223663739
Pubmed

Progressive Myoclonus Epilepsy, Lafora Type

NHLRC1 EPM2A

3.10e-052194220301563
Pubmed

Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.

FLNA FLNC

3.10e-05219427689010
Pubmed

Structural and Functional Brain Abnormalities in Mouse Models of Lafora Disease.

NHLRC1 EPM2A

3.10e-052194233092303
Pubmed

RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells.

RASAL3 ICAM5

3.10e-052194225652366
Pubmed

IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1.

TNFSF14 LTBR

3.10e-052194221072055
Pubmed

Recruitment and activation of naive T cells in the islets by lymphotoxin beta receptor-dependent tertiary lymphoid structure.

TNFSF14 LTBR

3.10e-052194216934497
Pubmed

Protein degradation and quality control in cells from laforin and malin knockout mice.

NHLRC1 EPM2A

3.10e-052194224914213
Pubmed

Lafora disease in the Indian population: EPM2A and NHLRC1 gene mutations and their impact on subcellular localization of laforin and malin.

NHLRC1 EPM2A

3.10e-052194218311786
Pubmed

Filamin isogene expression during mouse myogenesis.

FLNA FLNC

3.10e-052194210679933
Pubmed

Age-Related microRNA Overexpression in Lafora Disease Male Mice Provides Links between Neuroinflammation and Oxidative Stress.

NHLRC1 EPM2A

3.10e-052194236674605
Pubmed

Immunohistochemical demonstration of transferrin receptor 1 and 2 in human hepatocellular carcinoma tissue.

TFR2 TFRC

3.10e-052194224901155
Pubmed

Inflammation in Lafora Disease: Evolution with Disease Progression in Laforin and Malin Knock-out Mouse Models.

NHLRC1 EPM2A

3.10e-052194227041370
Pubmed

The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin β and Lymphotoxin β Receptor Interact to Regulate Intestinal Inflammation.

TNFSF14 LTBR

3.10e-052194230524422
Pubmed

A novel structural unit in the N-terminal region of filamins.

FLNA FLNC

3.10e-052194224469451
Pubmed

Impaired malin expression and interaction with partner proteins in Lafora disease.

NHLRC1 EPM2A

3.10e-052194238588813
Pubmed

[Association between the polymorphisms of TMPRSS6 and the levels of serum ferrtin and soluble transferrin receptor in pregnant women in Lüliang Area of Shanxi Province].

TMPRSS6 TFRC

3.10e-052194230593316
Pubmed

Mild Lafora disease: clinical, neurophysiologic, and genetic findings.

NHLRC1 EPM2A

3.10e-052194225270369
Pubmed

Identification of a novel putative interaction partner of the nucleoporin ALADIN.

PGRMC2 AAAS

3.10e-052194227754849
Pubmed

Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment.

NHLRC1 EPM2A

3.10e-052194217337485
Pubmed

Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and development.

SMPD3 SMPD2

3.10e-052194215764706
Pubmed

Four novel and two recurrent NHLRC1 (EPM2B) and EPM2A gene mutations leading to Lafora disease in six Turkish families.

NHLRC1 EPM2A

3.10e-052194222047982
Pubmed

Heterotypic interactions between transferrin receptor and transferrin receptor 2.

TFR2 TFRC

3.10e-052194212406888
Pubmed

Polymorphic variants of LIGHT (TNF superfamily-14) alter receptor avidity and bioavailability.

TNFSF14 LTBR

3.10e-052194220592286
Pubmed

Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia.

GRIN1 GRIN2C

3.10e-052194223070074
Pubmed

Hydrolysis of sphingosylphosphocholine by neutral sphingomyelinases.

SMPD3 SMPD2

3.10e-052194214741383
Pubmed

Increased liver tumor formation in neutral sphingomyelinase-2-deficient mice.

SMPD3 SMPD2

3.10e-052194229567647
Pubmed

Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylase.

NHLRC1 EPM2A

3.10e-052194224068615
Pubmed

GIGYF1-disturbed IGF-1R recycling: a potential contributor to autism spectrum disorder pathogenesis?

GIGYF1 IGF1R

3.10e-052194236189799
Pubmed

The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara.

HECTD3 TRIOBP

3.10e-052194218194665
Pubmed

MUC1 promotes lymph node metastasis in esophageal squamous cell carcinoma by downregulating DNAJB6 expression.

DNAJB6 MUC1

3.10e-052194237584547
Pubmed

LIGHT (TNFSF14) Increases the Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells.

TNFSF14 LTBR

3.10e-052194227835685
Pubmed

Increased endoplasmic reticulum stress and decreased proteasomal function in lafora disease models lacking the phosphatase laforin.

NHLRC1 EPM2A

3.10e-052194219529779
Pubmed

Glycogen phosphomonoester distribution in mouse models of the progressive myoclonic epilepsy, Lafora disease.

NHLRC1 EPM2A

3.10e-052194225416783
Pubmed

Role of TfR2-Y250X and TfR1- rs3817672 Single Nucleotide Polymorphism on Pathophysiology of Iron Deficiency Anemia.

TFR2 TFRC

3.10e-052194231793267
Pubmed

Increased oxidative stress and impaired antioxidant response in Lafora disease.

NHLRC1 EPM2A

3.10e-052194224838580
Pubmed

Transferrin facilitates the formation of DNA double-strand breaks via transferrin receptor 1: the possible involvement of transferrin in carcinogenesis of high-grade serous ovarian cancer.

TFR2 TFRC

3.10e-052194226549031
Pubmed

Novel mutations in EPM2A and NHLRC1 widen the spectrum of Lafora disease.

NHLRC1 EPM2A

3.10e-052194220738377
Pubmed

Dimerization of the glucan phosphatase laforin requires the participation of cysteine 329.

NHLRC1 EPM2A

3.10e-052194223922729
Pubmed

LIGHT induces cell proliferation and inflammatory responses of rheumatoid arthritis synovial fibroblasts via lymphotoxin beta receptor.

TNFSF14 LTBR

3.10e-052194218412315
Pubmed

Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity.

NHLRC1 EPM2A

3.10e-052194222186021
Pubmed

Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy.

NHLRC1 EPM2A

3.10e-052194222186026
Pubmed

Sensitive quantification of α-glucans in mouse tissues, cell cultures, and human cerebrospinal fluid.

NHLRC1 EPM2A

3.10e-052194232817315
Pubmed

Astrocytes: new players in progressive myoclonus epilepsy of Lafora type.

NHLRC1 EPM2A

3.10e-052194229408991
Pubmed

Dendritic spine abnormalities correlate with behavioral and cognitive deficits in mouse models of Lafora disease.

NHLRC1 EPM2A

3.10e-052194232785985
Pubmed

A LIGHT-HVEM/LTβR axis contributes to the fibrosis of intrauterine adhesion.

TNFSF14 LTBR

3.10e-052194235987137
Pubmed

Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells.

SMPD3 SMPD2

3.10e-052194215051724
Pubmed

Modulation of functional properties of laforin phosphatase by alternative splicing reveals a novel mechanism for the EPM2A gene in Lafora progressive myoclonus epilepsy.

NHLRC1 EPM2A

3.10e-052194218617530
Pubmed

Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism.

SMPD3 SMPD2

3.10e-052194212566438
Pubmed

Neutral sphingomyelinases and nSMase2: bridging the gaps.

SMPD3 SMPD2

3.10e-052194216938269
Pubmed

Lafora progressive myoclonus epilepsy: a meta-analysis of reported mutations in the first decade following the discovery of the EPM2A and NHLRC1 genes.

NHLRC1 EPM2A

3.10e-052194219267391
Pubmed

Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth.

CLEC14A MMRN2

3.10e-052194225745997
Pubmed

Enhanced sensitivity of laforin- and malin-deficient mice to the convulsant agent pentylenetetrazole.

NHLRC1 EPM2A

3.10e-052194225309313
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ADGRB2 DDN ARMCX4 LMTK3 KCNB1 NRXN1 SNAP91 BSN SHROOM3 TRIOBP GRIN1 SIPA1 CELSR2 ICAM5 DCHS1 AGRN UNC13A

3.15e-059631941728671696
Pubmed

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.

TMPRSS6 TFR2 TFRC

3.62e-0512194325352340
Pubmed

Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.

GRIN3B GRIN1 GRIN2C

5.95e-0514194315749123
Cytoband11q13

NDUFV1 ZNHIT2 SIPA1 ROM1 ZFTA

1.52e-04118194511q13
Cytoband7q36.1

ZNF862 SSPOP ZNF212 ZNF746

2.82e-047419447q36.1
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN3B GRIN1 GRIN2C

1.11e-05712531201
GeneFamilyImmunoglobulin like domain containing

CADM4 IGSF5 DSCAML1 SEMA3B IGDCC4 SIGIRR ICAM5

3.91e-041931257594
GeneFamilySolute carriers

SLC22A7 SLC8B1 SLC35A4 SLC16A11 SLC35E3 SLC5A12 SLC25A48 SLC39A7 SLC49A4 SLC13A5

4.21e-0439512510752
GeneFamilyEMI domain containing

EMID1 MMRN2

9.73e-0471252540
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

SPINT1 PLK5 DACT2 DSCAML1 SCN4B VIPR1 NPR3 COL15A1 STBD1 GRIN1 RAB11FIP1 SIGIRR SORCS3 RAB11FIP4 NALF2 HR

7.04e-0934519416M2009
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

SPINT1 PLK5 DACT2 DSCAML1 SCN4B VIPR1 NPR3 COL15A1 STBD1 GRIN1 RAB11FIP1 SIGIRR SORCS3 RAB11FIP4 NALF2 HR

7.64e-0934719416MM860
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

SPINT1 PLK5 DACT2 DSCAML1 SCN4B VIPR1 NPR3 STBD1 RAB11FIP1 SORCS3 RAB11FIP4 NALF2 HR

2.31e-0635019413M1949
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

SPINT1 PLK5 DACT2 DSCAML1 SCN4B VIPR1 NPR3 STBD1 RAB11FIP1 SORCS3 RAB11FIP4 NALF2 HR

2.86e-0635719413MM828
CoexpressionBRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A

LHFPL4 SPINT1 MZB1 EMID1 IGSF5 PRSS36 SIAE BRCA2 SNAP91 CMA1 FLNC COL11A2 RAB11FIP1 TFR2 CD93 ARSB SIGIRR ASL DCHS1 AGRN SMAD6

3.60e-0689919421M2242
CoexpressionBRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A

LHFPL4 SPINT1 MZB1 EMID1 IGSF5 PRSS36 SIAE BRCA2 SNAP91 CMA1 FLNC COL11A2 RAB11FIP1 TFR2 CD93 ARSB SIGIRR ASL DCHS1 AGRN SMAD6

6.05e-0693019421MM893
CoexpressionGSE13229_IMM_VS_MATURE_NKCELL_UP

NHLRC1 MLEC BRCA2 VARS1 MOV10 TACC2 IGDCC4 TFRC CD93

1.93e-052001949M3205
CoexpressionMARTENS_TRETINOIN_RESPONSE_UP

NHLRC1 TNFSF14 PLK5 DACT2 IZUMO1R RNF215 CTAG2 CMA1 GRIN3B FOXI1 GPR25 GRIN1 BATF2 CD93 CELSR2 CLEC14A FOXI2 SLC13A5 ACKR1

2.14e-0585519419M2098
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN

IZUMO1R CEP68 TET3 VIPR1 TTC28 PLEKHG2 IGF1R SLC49A4

2.91e-051621948M7002
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IGSF5 RAB11FIP1 CD93 ARAP3 SIGIRR CLEC14A HELZ2 MMRN2 SMAD6

1.47e-0814419491c118b22c2ff3a526a5207d6c9d772636ee065fd
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IGSF5 RAB11FIP1 CD93 ARAP3 SIGIRR CLEC14A HELZ2 MMRN2 SMAD6

1.98e-081491949d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HYAL4 NUTM2B FOXI1 FFAR1 GPAT3 TFRC FOXI2 SORCS3 SLC13A5

1.98e-081491949cc911b454fe4e4b489885b9920baa7eb01a027ba
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF14 EMID1 IGSF5 CMA1 BSN PIM2 GPR25 RASAL3 MUC1

2.79e-08155194993513bab53b40e9c3c91ab8e3316ea00a4f66cd2
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

SIAE KCNB1 SCN4B SDS COL15A1 TFR2 CLEC14A ASL MMRN2

6.52e-081711949c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCellPCW_10-12-Neuronal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CADM4 NRXN1 SEMA3B HS3ST4 NPR3 COL15A1 CELSR2 SORCS3 HR

1.06e-071811949381b553e2cae65ce6be100662a5f9f963353840c
ToppCellPCW_10-12-Neuronal-Neuronal_postreplicative|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CADM4 NRXN1 SEMA3B HS3ST4 NPR3 COL15A1 CELSR2 SORCS3 HR

1.06e-0718119491aebb62ed4439db444ee9d30688212b86ee3d9ef
ToppCellPCW_10-12-Neuronal-Neuronal_postreplicative-neuro_NA|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CADM4 NRXN1 SEMA3B HS3ST4 NPR3 COL15A1 CELSR2 SORCS3 HR

1.06e-0718119496aee2ddee4790250ef3b2ef0038bd9839925c995
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

ARHGAP26 VIPR1 NPR3 TTC28 CD93 ARAP3 CLEC14A MMRN2 SMAD6

1.40e-07187194981affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VWA5B2 NRXN1 SNAP91 SMPD3 BSN BAIAP3 SYT13 PHOX2A UNC13A

1.47e-071881949c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LHFPL4 DSCAML1 NRXN1 SNAP91 SMPD3 BAIAP3 SYT13 FOXI1 UNC13A

2.27e-071981949e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IGSF5 RAB11FIP1 CD93 ARAP3 SIGIRR CLEC14A HELZ2 MMRN2

3.94e-071541948b0735365de153d4586ca17896431d7bd9c7d8eac
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPINT1 DSCAML1 PRSS36 SH3YL1 SEMA3B SLC25A48 STBD1 MUC1

5.53e-0716119481e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF14 IGSF5 CMA1 SLC16A11 BAIAP3 PIM2 TMPRSS6 ARSB

6.66e-071651948e24621c8d4dbafb407033d832fe9337f13feae34
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMID1 ADGRB2 CMA1 BAIAP3 PIM2 GPR25 ARSB RASAL3

7.29e-071671948cde82e3dacf347226a78873b166608b7851b34d4
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMID1 ADGRB2 CMA1 BAIAP3 PIM2 GPR25 ARSB RASAL3

7.29e-0716719486f54a699d9266c5f09ed890a11b403a6c8476fc1
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-5|TCGA-Bladder / Sample_Type by Project: Shred V9

EMID1 NRXN1 MRGPRG BSN SYT13 COL11A2 GRIN2C UNC13A

7.98e-0716919489c4e83fe8225d16173a103bf5a57b17d623be923
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 DSCAML1 BAIAP3 TARBP1 GRIN1 IRGQ KIFC2 UNC13A

1.13e-0617719488abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VIPR1 NPR3 CD93 ARAP3 CLEC14A MMRN2 ACKR1 SMAD6

1.34e-0618119482c660fcf0404c155955b67ab2958d6e6b0e30024
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

VWA5B2 DSCAML1 NRXN1 SNAP91 SMPD3 BSN SYT13 UNC13A

1.39e-06182194857bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPINT1 DACT2 PRSS36 SH3YL1 SHROOM3 STBD1 RAB11FIP1 MUC1

1.45e-06183194806ac66726ec53db810ebb90ec69cfdb903da53f6
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 MZB1 PRDM9 USP51 SH3TC2 GRIN1 CD93 CLEC14A

1.45e-061831948bc24145855bf4d027a8058bf92bc796c10f241bb
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPINT1 PRSS36 SH3YL1 SEMA3B SHROOM3 STBD1 RAB11FIP1 MUC1

1.45e-061831948274483009b309289e4cb84beedf6806430db6ff6
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 MZB1 PRDM9 USP51 SH3TC2 GRIN1 CD93 CLEC14A

1.45e-0618319484c325ee6da070513097a11445ec95b0415ffd8a2
ToppCellNasal_Brush-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

TNFSF14 PEX6 CPED1 SORT1 SIAE HECTD3 AAAS IGF1R

1.64e-061861948f5aa91dbef29f7efa2b9a728c6539d7541340cd4
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VWA5B2 DSCAML1 NRXN1 SNAP91 SMPD3 BSN SYT13 UNC13A

1.64e-061861948b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellEndothelial-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

NPR3 CD93 ARAP3 CLEC14A DCHS1 MMRN2 ACKR1 SMAD6

1.64e-061861948796cbae2a417502aaf0891fc9c382bbfd88967fe
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DACT2 MRGPRG SMPD3 NID2 FLNC ZFTA ACKR1 FAM131B

1.71e-061871948fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 DDN BSN BHLHA9 GRIN1 KIFC2 CELSR2 ICAM5

1.71e-061871948e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 DDN BSN BHLHA9 GRIN1 KIFC2 CELSR2 ICAM5

1.71e-06187194824cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB2 DDN BSN BHLHA9 GRIN1 KIFC2 CELSR2 ICAM5

1.71e-0618719482f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IGSF5 RAB11FIP1 CD93 CLEC14A HELZ2 MMRN2 MUC1

1.77e-061311947d5bc40cd585582856881081b7130dec3515b4ae0
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IGSF5 CD93 ARAP3 SIGIRR CLEC14A HELZ2 MMRN2

1.77e-061311947308ddb7fe113eac5dbeb9cb0b688d9e09275ce5e
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

VWA5B2 GAD2 LHFPL4 DSCAML1 NRXN1 BAIAP3 TMPRSS6 UNC13A

1.92e-061901948b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCellCOVID-19-Endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

VIPR1 NPR3 TTC28 CD93 ARAP3 CLEC14A ACKR1 SMAD6

1.92e-0619019489fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 NPR3 COL15A1 CD93 ARAP3 CLEC14A MMRN2 SMAD6

2.16e-0619319485d42979d811ee13a07dee08a3743a90776017cb4
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 NPR3 COL15A1 CD93 ARAP3 CLEC14A MMRN2 SMAD6

2.16e-06193194897c0730aad9135ac681250b3871cc094a28f80a7
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 ADGRB2 KCNB1 BSN GRIN1 CELSR2 ICAM5 UNC13A

2.16e-0619319488689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 NPR3 COL15A1 CD93 ARAP3 CLEC14A MMRN2 SMAD6

2.16e-06193194895e64b9580d30c28702639a043a8b72ce1cadeb6
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 ADGRB2 KCNB1 BSN GRIN1 CELSR2 ICAM5 UNC13A

2.16e-061931948be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 ADGRB2 KCNB1 BSN GRIN1 CELSR2 ICAM5 UNC13A

2.16e-0619319480c652ebe22ce5d2927599dd97ef1920547858395
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP26 SLC8B1 CPVL SDS GPAT3 PLEKHG2 TFRC SLC49A4

2.24e-0619419483043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellEndothelial-A-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

NPR3 CD93 ARAP3 CLEC14A DCHS1 MMRN2 ACKR1 SMAD6

2.24e-061941948e656ac5539e59e321b46706cb8cc423b2c3358a0
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type|TCGA-Adrenal / Sample_Type by Project: Shred V9

MLEC EMID1 SLC8B1 SLC35A4 CBLN3 IGDCC4 AAAS MFSD5

2.33e-061951948c3280bb6219e2eff5e24ef45aa2d76479a562122
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT2 KCNB1 SNAP91 SMPD3 BSN GRIN1 ICAM5 UNC13A

2.33e-061951948ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Striatum / BrainAtlas - Mouse McCarroll V32

IGSF5 RAB11FIP1 SIGIRR CLEC14A HELZ2 MMRN2 SMAD6

2.38e-061371947306b11b3b9e5fd562d845fb5eaa4ac982864efce
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK|Striatum / BrainAtlas - Mouse McCarroll V32

IGSF5 RAB11FIP1 SIGIRR CLEC14A HELZ2 MMRN2 SMAD6

2.38e-061371947d37f425b13bc046baa1f8619b98a16b936f88ff6
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LHFPL4 DSCAML1 NRXN1 SNAP91 SMPD3 BAIAP3 SYT13 UNC13A

2.61e-0619819488f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellproximal-Endothelial-Artery-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VIPR1 NPR3 BATF2 CD93 ARAP3 CLEC14A MMRN2 SMAD6

2.61e-061981948a56b80bdc824e4cc60366f273fb616cd0efec456
ToppCellproximal-3-Endothelial-Artery|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VIPR1 NPR3 BATF2 CD93 ARAP3 CLEC14A MMRN2 SMAD6

2.61e-061981948946f72b594d22ae7b8e4c22483814c284cb43eea
ToppCellproximal-Endothelial-Artery|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VIPR1 NPR3 BATF2 CD93 ARAP3 CLEC14A MMRN2 SMAD6

2.61e-0619819480e5572298676b6c2a2b1a77967574020b664aebd
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

IGSF5 RAB11FIP1 CD93 SIGIRR CLEC14A HELZ2 MMRN2

2.62e-06139194734398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

IGSF5 RAB11FIP1 CD93 SIGIRR CLEC14A HELZ2 MMRN2

2.62e-061391947450c4152c9fe4ec503271bb3cf93739918c59509
ToppCellBiopsy_Control_(H.)-Endothelial|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

VIPR1 NPR3 CD93 ARAP3 CLEC14A MMRN2 ACKR1 SMAD6

2.81e-0620019486a9b6a4b4f204598290ae21c87ddb42ac95dfc4c
ToppCellBiopsy_Control_(H.)-Endothelial-Endothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

VIPR1 NPR3 CD93 ARAP3 CLEC14A MMRN2 ACKR1 SMAD6

2.81e-0620019480242d465da2dfba0da629a43e152949c5192465b
ToppCellBiopsy_IPF-Endothelial-Endothelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

VIPR1 COL15A1 CD93 CLEC14A DCHS1 MMRN2 ACKR1 SMAD6

2.81e-06200194839b4faad5700b3108f851f0df7fea3d298514465
ToppCellBronchial-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VIPR1 NPR3 CD93 ARAP3 CLEC14A MMRN2 ACKR1 SMAD6

2.81e-062001948ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCellBiopsy_IPF-Endothelial|Biopsy_IPF / Sample group, Lineage and Cell type

VIPR1 COL15A1 CD93 CLEC14A DCHS1 MMRN2 ACKR1 SMAD6

2.81e-0620019487ccd3b617838b39da814278dc0e12384013401ce
ToppCellfacs-Lung-nan-3m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 CMA1 BAIAP3 PIM2 GPR25 ARSB RASAL3

6.92e-06161194733de3e8b3238fcfc66dfbf89a913a07d464d6c35
ToppCellfacs-Lung-nan-3m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 CMA1 BAIAP3 PIM2 GPR25 ARSB RASAL3

6.92e-061611947ae1cee34361dde9964581cca99a29578c3b3bd99
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF5 LMTK3 PRAG1 CMA1 BAIAP3 VIPR1 RASAL3

7.21e-0616219470321fc954ae4ad67ca438cbbc84632562d222188
ToppCelldroplet-Lung-nan-3m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 ADGRB2 CMA1 BAIAP3 GPR25 ARSB RASAL3

7.21e-0616219474b490989005bb03d4e7bbea01580f8548eff150f
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF5 LMTK3 PRAG1 CMA1 BAIAP3 VIPR1 RASAL3

7.21e-0616219475731f9514434296132df4bc86f78ce87b07cdeca
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 ADGRB2 CMA1 BAIAP3 GPR25 ARSB RASAL3

7.21e-061621947e4a09bf1a51710f6c57e6e01edf8b4619459d96d
ToppCellE12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NBEAL2 COL15A1 SIPA1 ARAP3 SIGIRR MMRN2 UNC13A

7.51e-061631947c21114826bee1b05b411984326fef6b6e0d05316
ToppCellE12.5-Endothelial-lymphatic_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NBEAL2 COL15A1 SIPA1 ARAP3 SIGIRR MMRN2 UNC13A

7.51e-0616319475d49414432db259a19df50d7944581d00b69f537
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF14 ADGRB2 CMA1 BAIAP3 PIM2 GPR25 RASAL3

7.51e-061631947d18fee517e0daed51f89703f94f218567c83cb03
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF14 ADGRB2 CMA1 BAIAP3 PIM2 GPR25 RASAL3

7.51e-061631947f4a6e28ad3c1fcbf62ed9b2bf09f65d2ab0b31d1
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMID1 ADGRB2 CMA1 BAIAP3 PIM2 ARSB RASAL3

7.51e-061631947a0315855c354e830e109d41bd6e3396488aa8de9
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMID1 IGSF5 CMA1 BAIAP3 GPR25 ARSB RASAL3

7.81e-061641947d4d08353c7322f97ea07dd583b08661d635fff20
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMID1 IGSF5 CMA1 BAIAP3 GPR25 ARSB RASAL3

7.81e-061641947c2cd4e4b88cc1b80a9494f59d31339007ff824c1
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 DGKH GRIN3B BAIAP3 SYT13 MUC1 UNC13A

8.13e-0616519474b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMID1 IGSF5 CMA1 BAIAP3 GPR25 ARSB RASAL3

8.13e-06165194788745bf7ecb0f7fc93077cea20171d40535dd56b
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EMID1 ADGRB2 CMA1 BAIAP3 PIM2 ARSB RASAL3

8.80e-061671947895844a45721988788d01120eb880603ba3ca139
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL15A1 CD93 ARAP3 CLEC14A DCHS1 MMRN2 ACKR1

9.88e-0617019471a568efcff9c39b3f709b55a05d24710450a2657
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL15A1 CD93 ARAP3 CLEC14A DCHS1 MMRN2 ACKR1

9.88e-06170194766d41d794790e621d72ac37af995510537103c9c
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DGKH COL15A1 CD93 CLEC14A MMRN2 ACKR1 SMAD6

1.03e-051711947b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCellE12.5-Endothelial-proliferative_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL15A1 SIPA1 CD93 ARAP3 SIGIRR CLEC14A MMRN2

1.07e-0517219472136170f6e1204734cec7dbf7b32e7d5179b92b5
ToppCellE12.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL15A1 SIPA1 CD93 ARAP3 SIGIRR CLEC14A MMRN2

1.07e-051721947ba99688e9f46671deccf824b1e77c6db0742d7df
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

NPR3 COL15A1 CD93 CLEC14A DCHS1 MMRN2 ACKR1

1.07e-051721947a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCellPCW_13-14-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CADM4 NRXN1 SEMA3B HS3ST4 SH3TC2 COL15A1 HR

1.15e-0517419470d8e737860120dcd3a6b57992c612595904d585e
ToppCell18-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

TET3 PIM2 CPOX TFR2 TFRC ACKR1 FAM131B

1.19e-051751947cc476b4244442418b8f21721a82a36209b556b36
ToppCell18-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

TET3 PIM2 CPOX TFR2 TFRC ACKR1 FAM131B

1.19e-0517519477130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 GAD2 LHFPL4 DSCAML1 SYT13 NALF2 UNC13A

1.24e-051761947da5933eb253f13e70296a50a2bb00ad5c19a2d99
ToppCellPCW_13-14-Neuronal-Neuronal_SCP|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CADM4 NRXN1 SEMA3B HS3ST4 SH3TC2 COL15A1 HR

1.28e-051771947621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM10 KCNB1 CD93 MOXD1 CLEC14A MMRN2 ACKR1

1.33e-0517819475cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCellControl-Epithelial_alveolar-AT_1-AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DSCAML1 PRSS36 SH3YL1 SEMA3B SHROOM3 STBD1 MUC1

1.33e-0517819471817bc520f3d23da8c0fa09bba50ae703a820cb1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 ARHGAP26 ADAM10 DSCAML1 CPVL MINDY2 ROM1

1.33e-051781947c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellfacs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM10 KCNB1 CD93 MOXD1 CLEC14A MMRN2 ACKR1

1.33e-051781947f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCellASK452-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

MZB1 INPP5B PPP1R13L SMPD3 SHROOM3 TACC2 RASAL3

1.38e-051791947c3cf49c069e66db16d2fce1de4c52a4c4fe7e832
ToppCellEndothelial-A-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

NPR3 CD93 CLEC14A MMRN2 ACKR1 SMAD6 AHNAK2

1.38e-051791947138fd6ba6bdbd0ad01c574168addf720b67a0fea
ToppCellEndothelial-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

VIPR1 NPR3 CD93 CLEC14A DCHS1 MMRN2 ACKR1

1.43e-0518019474c3376169770ee9f9283daae44c17f35e46bfd19
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNB1 HUS1B CD93 MOXD1 CLEC14A MMRN2 ACKR1

1.48e-05181194772c28baf4fd417ff4a7068603830d55074960144
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 GAD2 BAIAP3 SYT13 TMPRSS6 MUC1 UNC13A

1.48e-0518119472392af8c7f040c23a7d416c2e37419954970c8f4
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNB1 HUS1B CD93 MOXD1 CLEC14A MMRN2 ACKR1

1.48e-0518119472ac4d3e8987d5a009d7908d8787e18165826202a
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNB1 HUS1B CD93 MOXD1 CLEC14A MMRN2 ACKR1

1.48e-0518119472628c7ac345eaaeecf8e34617e81948925962cb9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 ARHGAP26 DSCAML1 CPVL SLC25A48 NID2 NPR3

1.48e-0518119476956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCelldroplet-Liver-Npc-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPINT1 MZB1 MRGPRG FLNC MOXD1 CELSR2 HR

1.59e-05183194799ab7a43527eb226027efbcd8c0b6a8e46fc3c93
ToppCelldroplet-Liver-Npc-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPINT1 MZB1 MRGPRG FLNC MOXD1 CELSR2 HR

1.59e-05183194728916f0597690ff534578be2cb715b485cb1de1a
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

SLC35E3 SMPD3 NID2 COL11A2 SLC13A5 RAB11FIP4 MUC1

1.65e-0518419471e03f9f08de5ad4d45388a95afad9f23ff0d0e28
DiseaseLafora disease

NHLRC1 EPM2A

3.91e-0521852cv:C0751783
DiseaseLafora disease (is_implicated_in)

NHLRC1 EPM2A

3.91e-0521852DOID:3534 (is_implicated_in)
DiseaseLafora Body Disease, Late Onset

NHLRC1 EPM2A

3.91e-0521852C0751784
DiseaseLafora Disease

NHLRC1 EPM2A

3.91e-0521852C0751783
Diseaseiron biomarker measurement, transferrin saturation measurement

TMPRSS6 TFR2 TFRC

8.39e-05141853EFO_0004461, EFO_0006333
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNC

1.17e-0431852DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNC

1.17e-0431852DOID:0111190 (implicated_via_orthology)
Diseasetransferrin saturation measurement

TMPRSS6 TFR2 TFRC

1.28e-04161853EFO_0006333
Diseaseachalasia (is_implicated_in)

VIPR1 AAAS

2.33e-0441852DOID:9164 (is_implicated_in)
DiseaseProgressive myoclonic epilepsy

NHLRC1 EPM2A

2.33e-0441852cv:C0751778
Diseasesortilin measurement

SORT1 CELSR2

2.33e-0441852EFO_0600000
DiseaseLafora disease (implicated_via_orthology)

NHLRC1 EPM2A

2.33e-0441852DOID:3534 (implicated_via_orthology)
DiseaseIron deficiency anemia

TMPRSS6 TFRC

2.33e-0441852C0162316
DiseaseEndometrial Stromal Sarcoma

NUTM2A NUTM2B

3.86e-0451852C0206630
Diseaseresponse to mepolizumab

NHLRC1 EPM2A

3.86e-0451852EFO_0008459
DiseaseClear cell sarcoma of kidney

NUTM2B NUTM2E

5.77e-0461852C0334488
Diseasecollagen alpha-2(XI) chain measurement

SLC39A7 COL11A2

5.77e-0461852EFO_0801490
Disease1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6) measurement

PEX6 MUC1

5.77e-0461852EFO_0800449
Diseasemagnesium measurement

SKOR2 VIPR1 SHROOM3 TTC28

7.96e-04661854EFO_0004845
Diseasepsoriasis (implicated_via_orthology)

SPINT1 LTBR

8.04e-0471852DOID:8893 (implicated_via_orthology)
Diseasehearing loss

SLC22A7 NID2 TRIOBP CLRN2

8.42e-04671854EFO_0004238
DiseaseMYELODYSPLASTIC SYNDROME

ARHGAP26 BRCA2 SMPD3 MPL

8.42e-04671854C3463824
Diseasetemporal horn of lateral ventricle volume measurement

NHLRC1 NRXN1 EPM2A COL15A1

1.10e-03721854EFO_0010333
Diseasesystolic blood pressure, alcohol drinking

IGSF5 MOV10 NPR3 SIPA1 LMAN1L

1.30e-031281855EFO_0004329, EFO_0006335
Diseasemitral valve prolapse (is_implicated_in)

FLNA DCHS1

1.37e-0391852DOID:988 (is_implicated_in)
Diseasegestational age

NHLRC1 TET3 VARS1 EPM2A ARSB

1.82e-031381855EFO_0005112
Diseaseimmature reticulocyte measurement

TMPRSS6 TFR2 TFRC

2.02e-03401853EFO_0803545
DiseaseCooley's anemia

TFR2 TFRC

2.48e-03121852C0002875
DiseaseThalassemia Intermedia

TFR2 TFRC

2.48e-03121852C0271979
Diseaseiron biomarker measurement, serum iron measurement

TMPRSS6 TFR2

2.48e-03121852EFO_0004461, EFO_0006332
Diseasecraniosynostosis (is_implicated_in)

FLNA SMAD6

2.48e-03121852DOID:2340 (is_implicated_in)
Diseasesurvival time, Sepsis

SLC5A12 TFRC

2.48e-03121852EFO_0000714, HP_0100806
DiseaseThalassemia Minor

TFR2 TFRC

2.48e-03121852C0085578
Diseasebeta Thalassemia

TFR2 TFRC

2.48e-03121852C0005283
Diseasecardiomyopathy (biomarker_via_orthology)

ADAM10 IGF1R

2.91e-03131852DOID:0050700 (biomarker_via_orthology)
Diseasesystolic blood pressure, alcohol consumption measurement

NPR3 SIPA1 LMAN1L

3.21e-03471853EFO_0006335, EFO_0007878
Diseasenephroblastoma (is_implicated_in)

BRCA2 IGF1R

3.39e-03141852DOID:2154 (is_implicated_in)
Diseasetransferrin receptor protein 1 measurement

TMPRSS6 TFRC

3.39e-03141852EFO_0802142
Diseasemyopathy (implicated_via_orthology)

FLNA FLNC COL15A1

3.41e-03481853DOID:423 (implicated_via_orthology)
Diseasehearing impairment

FOXI1 COL11A2 TRIOBP ARSB

3.42e-03981854C1384666
Diseasemean arterial pressure, alcohol drinking

MOV10 NPR3 SIPA1 LMAN1L

3.42e-03981854EFO_0004329, EFO_0006340
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GIGYF1 GRIN2C RASAL3

3.61e-03491853DOID:0060037 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

GAD2 BSN GRIN2C SLC13A5 UNC13A

3.73e-031631855DOID:1826 (implicated_via_orthology)
Diseasepancreas fat measurement

NHLRC1 EPM2A

3.89e-03151852EFO_0600049
Diseasehepcidin:transferrin saturation ratio

TMPRSS6 FOXI2

3.89e-03151852EFO_0007902
DiseaseHemoglobin F Disease

TFR2 TFRC

3.89e-03151852C0019025
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

FOXI1 COL11A2 TRIOBP

4.05e-03511853cv:CN043650
DiseaseHypermetropia

DSCAML1 GRIN2C HSD17B12 AGRN

4.08e-031031854HP_0000540
Diseasemean arterial pressure, alcohol consumption measurement

NPR3 SIPA1 LMAN1L

4.28e-03521853EFO_0006340, EFO_0007878
DiseaseSynostotic Posterior Plagiocephaly

WDR35 SMAD6

4.43e-03161852C1833340
DiseaseCraniosynostosis, Type 1

WDR35 SMAD6

4.43e-03161852C4551902
DiseaseAcrocephaly

WDR35 SMAD6

4.43e-03161852C0030044
DiseaseTrigonocephaly

WDR35 SMAD6

4.43e-03161852C0265535
DiseaseScaphycephaly

WDR35 SMAD6

4.43e-03161852C0265534
DiseaseSynostotic Anterior Plagiocephaly

WDR35 SMAD6

4.43e-03161852C2931150
DiseaseMetopic synostosis

WDR35 SMAD6

4.43e-03161852C1860819
Diseaseage-related hearing impairment

ADGRB2 SNAP91 NID2 COL11A2 TTC28 TRIOBP CLRN2

4.50e-033241857EFO_0005782
DiseaseBrachycephaly

WDR35 SMAD6

5.00e-03171852C0221356
Diseaselateral occipital cortex volume measurement

NHLRC1 EPM2A

5.00e-03171852EFO_0010311
DiseaseFamilial Progressive Myoclonic Epilepsy

NHLRC1 EPM2A

5.00e-03171852C0751777
DiseaseAtypical Inclusion-Body Disease

NHLRC1 EPM2A

5.00e-03171852C0751776
DiseaseMyoclonic Epilepsies, Progressive

NHLRC1 EPM2A

5.00e-03171852C0751778
DiseaseBiotin-Responsive Encephalopathy

NHLRC1 EPM2A

5.00e-03171852C0751780
DiseaseMay-White Syndrome

NHLRC1 EPM2A

5.00e-03171852C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

NHLRC1 EPM2A

5.00e-03171852C0751781
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

ADAM10 BRCA2 SHROOM3 CELSR2

5.32e-031111854EFO_0004530, EFO_0008595
Diseaselipoprotein A measurement

DSCAML1 SMPD3 CELSR2 MUC1

5.49e-031121854EFO_0006925
Diseaseserum hepcidin measurement

DGKH TMPRSS6

5.60e-03181852EFO_0004504
DiseaseAction Myoclonus-Renal Failure Syndrome

NHLRC1 EPM2A

5.60e-03181852C0751779
Diseaseperitonsillar abscess

PRAG1 LTBR

5.60e-03181852EFO_0007429
Diseasewaist circumference

ARHGAP26 FASN NRXN1 DNAJB6 TFRC MOXD1 CLEC14A HSD17B12

5.88e-034291858EFO_0004342
Diseasebody weight

INPP5B DGKH FASN NRXN1 SLC16A11 SMPD3 CPVL NID2 NPR3 WDR59 MOXD1 IGF1R ASL HSD17B12 FOLH1B MUC1

6.04e-03126118516EFO_0004338
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA COL11A2

6.23e-03191852DOID:2256 (is_implicated_in)
Diseaselevel of Phosphatidylethanolamine (18:0_20:4) in blood serum

ADAM10 MINDY2

6.23e-03191852OBA_2045140
Diseasehemifacial microsomia

NID2 SHROOM3

6.23e-03191852MONDO_0015398

Protein segments in the cluster

PeptideGeneStartEntry
GLDGTSVPLGAAQWG

SYT13

261

Q7L8C5
WFKGGPGGGLIIIDS

UNC13A

476

Q9UPW8
ALRVPVGAEGWGGTE

nan

126

Q8N976
LGWGLPALVVAVSVG

ADGRB2

1041

O60241
RGGGVTNLLWSPDGS

AAAS

286

Q9NRG9
APGLWLSGFGLLRGD

ARAP3

816

Q8WWN8
VGWGLGSASPEGQKA

CTAG2

151

O75638
TGTAWLEADSPGLGG

CSPG5

96

O95196
EAEGGLISPVWGAEG

CEP68

46

Q76N32
GLGPGLLEQGDLGSW

CPED1

136

A4D0V7
AAGQALKGLAWPEGA

BAIAP3

816

O94812
LKGLAWPEGATGPEG

BAIAP3

821

O94812
PGWGGKTVLQAALGV

ALS2

36

Q96Q42
GVLGLAWVGAPSGSS

ADAM10

326

O14672
VAEGPGLAQASGGSW

BHLHA9

191

Q7RTU4
VRTGGAGSKWAALGP

AFDN-DT

121

Q9Y6Z5
AAAAALGGRWPFGDG

GPR25

96

O00155
DGALWLGGLPELPVG

AGRN

2011

O00468
DPSLPLKGFSWVGGG

CD93

106

Q9NPY3
LGGWSFGLKIPSEAG

ABCA13

4366

Q86UQ4
QVPGLTLGLTVGIWG

ACKR1

161

Q16570
GGSFAGLEPMGLLWA

ACOT2

131

P49753
WGVLLVGGPGSGKTA

ANKRD50

71

Q9ULJ7
PPAGGATAWGDLLGE

SNAP91

371

O60641
GWGVPAFITGLAVGL

CELSR2

2486

Q9HCU4
LGLGEGAGPETLEGW

DDN

416

O94850
LGLPGNGLVLWVAGL

C3AR1

36

Q16581
AWAGTLDQSGGGSKP

ARMCX4

1376

Q5H9R4
PCVLLGWALLAGGTG

NPR3

11

P17342
LISGVGDPGQGAAWL

IGDCC4

1166

Q8TDY8
GDPGQGAAWLDRELG

IGDCC4

1171

Q8TDY8
AGAPGVRAELWLDGA

RASAL3

321

Q86YV0
MAGGAGWSGAPAALL

RAB11FIP4

1

Q86YS3
AGWSGGGPTIETLEL

NOBOX

326

O60393
AAGTKAGPAGAWPVG

YOD1

26

Q5VVQ6
LLLGAGVPGAWGQAG

DCHS1

31

Q96JQ0
GVPGAWGQAGSLDLQ

DCHS1

36

Q96JQ0
EIIGWPGGSGDGIFS

GAD2

226

Q05329
AAGDGALALQEPGLW

EPM2A

46

O95278
GALTGLGLWVVGLVP

SLC16A11

316

Q8NCK7
VVGGEESWGGPLLAA

SLC16A11

331

Q8NCK7
LNFGPEWLRALSGGG

GIGYF1

6

O75420
KPGELGGRISGSVAW

NGLY1

451

Q96IV0
GSLGWEVAPSGQGER

IZUMO1R

111

A6ND01
LGTVWGGPANLEAIA

ECHDC1

286

Q9NTX5
LFSLGGPLGWGLLGA

MMRN2

6

Q9H8L6
VPGALGAALWEAGSP

MMRN2

811

Q9H8L6
VAGAAGAGLPESVIW

MLEC

36

Q14165
VGSVLGGLASWDGIG

LMAN1L

121

Q9HAT1
GKLWGGRFVGAVDPI

ASL

6

P04424
QSGAGVPGWGIALLV

MUC1

1151

P15941
LPLERGDAVAGWGGH

LMTK3

681

Q96Q04
AGADGPLALYGWGAL

BSN

1621

Q9UPA5
LPWEDGRSGLLSGGL

B4GALT7

11

Q9UBV7
DLGAVGGGPLLWVNA

FOXI2

31

Q6ZQN5
GAPGGLAGADLAWLS

FOXI2

76

Q6ZQN5
AGVFIPSLLIGAAWG

CLCN7

511

P51798
DAPVVLWLQGGPGGS

CPVL

101

Q9H3G5
SGLDGEGLWSPGSQV

HR

1036

O43593
GGGSPTSLWGLLFLS

IGF1R

6

P08069
LWVAVGGAAGGAALL

ICAM5

836

Q9UMF0
EGGGWAAAALALLTG

PGRMC2

36

O15173
PALGWALLGTSLGPG

PEX6

101

Q13608
PVAGVGNGGSLWPRE

FAM214B

201

Q7L5A3
AWGPGLETGQVGKSA

FLNC

576

Q14315
LGGHRDSWVFGGIDP

FOLH1B

66

Q9HBA9
GGGGKPQAAVASWLA

GXYLT1

36

Q4G148
PQAAVASWLAGGGRG

GXYLT1

41

Q4G148
LVLGLSAAPGWAGAP

COL11A2

16

P13942
GEGLQLTLWEQGSPG

PLK5

291

Q496M5
LGWESRASGPGEGLV

KIF24

681

Q5T7B8
ELLWGQGSGPEFGLV

LMLN2

431

A0A1B0GTW7
GDLLAVVASPGSGAW

NALF2

226

O75949
AGKWHLGVGPEGAFL

ARSA

121

P15289
LGCWAELGSGLEFPG

NRXN1

21

Q9ULB1
PLGTGNDLARVLGWG

DGKH

416

Q86XP1
AGGAALLSEWKGTGP

SMPD3

106

Q9NY59
VSSVLRPGGDVSGWG

LHFPL4

221

Q7Z7J7
PLLGGDTDWAPGVGA

FAM131B

251

Q86XD5
PLWEEGGSGARIFGN

OTUD3

296

Q5T2D3
IVGLGGPVGNGLVLW

MRGPRG

21

Q86SM5
IGGLFGWLFALEKPG

NID2

586

Q14112
AGLGVWNEASDLPLG

PRDM9

256

Q9NQV7
AGGGAGEAAILLWTP

SMPD2

346

O60906
LGPGALLEAELLGGW

PRSS36

456

Q5K4E3
GGTGGAVSELVPWSV

PCDHA4

571

Q9UN74
PWDPLASAAGLKEGG

DNAJB6

291

O75190
SLGFSLPTWGKVGLG

IGSF5

256

Q9NSI5
RWLDPGAFGTLGVGA

ILVBL

486

A1L0T0
AILFAIGGWSGGSPT

KLHL10

291

Q6JEL2
IGGWSGGSPTNAIEA

KLHL10

296

Q6JEL2
TGGSTAPEVGWRGAL

KCNB1

616

Q14721
WSTDGGGRLLVFAPG

DACT2

371

Q5SW24
CHLGLVFGLEAPGGW

FFAR1

136

O14842
GKGIQLADGGWLIPS

BRCA2

2576

P51587
IAIQGGLTELPWDGG

GPAT3

391

Q53EU6
LTWIPGDNGGSSIRG

DSCAML1

1401

Q8TD84
AWGPGLEGGVVGKSA

FLNA

581

P21333
IPLGVFAGWSGVLDL

SLC49A4

291

Q96SL1
LLGCWDQAEGLLGPG

BATF2

96

Q8N1L9
GVSAALGAAGVVLWG

HYAL3

306

O43820
GESAALGAAGIVIWG

HYAL4

326

Q2M3T9
LLLLWAAAAGPGAGQ

CADM4

11

Q8NFZ8
GPGLGEWAVVTGSTD

HSD17B12

46

Q53GQ0
FGPAGSGGLHEARLW

HUS1B

41

Q8NHY5
LWEGGVRGVGFVASP

ARSB

321

P15848
EARPQGAGSVLFWGG

INPP5B

191

P32019
ALGAGWAQEGSEPVL

CBLN3

26

Q6UW01
LPGGGAAWSIGAAPF

EMID1

16

Q96A84
SPGDGGLQDQVGAWG

EMID1

186

Q96A84
LPSVSGLGGSDLGWL

FOXI1

96

Q12951
LAVALIAGWGPGDGR

HELZ2

521

Q9BYK8
EGLPGLAVQWGAIGD

FASN

2051

P49327
PTAGAEAEGSGLGWG

COL15A1

586

P39059
GGSLAPLAALLDGVW

SLC22A7

476

Q9Y694
LWEKPGAIALSVGGG

SDS

156

P20132
VPWGIVLLLGGGFAL

SLC13A5

406

Q86YT5
GPWVGTGLAAALAGL

CPOX

71

P36551
LPWRESSLDGLGGTG

PPP1R13L

286

Q8WUF5
GGGGAQDAWLRTPLA

HS3ST4

131

Q9Y661
QVSWALGALSSGGPG

KIFC2

371

Q96AC6
GVAAEAVASWIGLGP

MFSD5

186

Q6N075
GGWGTLVNPTGLALC

NHLRC1

121

Q6VVB1
GAALGALSFLWPAGG

IRGQ

571

Q8WZA9
EPDGLLVWVLAGALG

SLC8B1

521

Q6J4K2
GAVATGDIGRVWPGT

MRPL3

241

P09001
RVSGEQSLTWGLGGP

NUTM2A

841

Q8IVF1
RVSGEQSLTWGLGGP

NUTM2B

841

A6NNL0
RVSGEQSLTWGLGGP

NUTM2E

841

B1AL46
VGSWRDGQLDLEPGG

GRIN3B

386

O60391
PGVWAAETSGGNGLG

MINDY2

41

Q8NBR6
GATAVAQLLWPAGLG

VARS1

71

P26640
GAWGGVSIPTGKGEL

TSGA10IP

176

Q3SY00
LAAGSWKEPAEGGGL

RAB11FIP1

361

Q6WKZ4
GAADGLSRWPHGLGL

SORT1

6

Q99523
LGQWADVSGGGPARS

SEC61A2

321

Q9H9S3
GQDVGLPWIGAEGLS

SSPOP

641

A2VEC9
GSSLLDVAEPGGPGW

SMAD6

101

O43541
VLGSWGPGLGDGVAA

LRRC56

481

Q8IYG6
WELLGPGESGSEGAG

MOV10

216

Q9HCE1
AGAEITWDATGGPGR

SORCS3

31

Q9UPU3
GVTGGWDNLLAVIPG

NDUFV1

306

P49821
PLEVALLWKVGAGGG

PIM2

81

Q9P1W9
LGWGSGLVAPLQEGS

NBEAL2

766

Q6ZNJ1
DGGKAPARWLGTGLL

SCN4B

6

Q8IWT1
PLVDWTAGGEAGFAG

SMG1

2421

Q96Q15
AGLGVWNEASDLPLG

PRDM7

256

Q9NQW5
EPGWLEGTLNGKTGL

ARHGAP26

791

Q9UNA1
KWSAPSAIGIAGLGG

SH3YL1

76

Q96HL8
LAALVGLLPWGGGTA

SFT2D3

181

Q587I9
PLWLGLAGPGAAADG

RNF215

31

Q9Y6U7
SVQWLKDGLPLGIGG

SIGIRR

46

Q6IA17
EPAGAVIWGFGTPGA

SIAE

41

Q9HAT2
PGAELQAAGSLVWGV

SIPA1

571

Q96FS4
APWGFTLKGGLEHGE

SHROOM3

36

Q8TF72
LVGIPGLGDSGWIAA

SCAMP2

236

O15127
LLGFPSPGWGEVSAL

SH3TC2

721

Q8TF17
AGWIGGAASVIVGHP

SLC25A48

11

Q6ZT89
AWGPGAAKSGVGTAL

TFRC

411

P02786
SLGAAKAPEGAWGGT

TRIOBP

1466

Q9H2D6
GRAGVLEELGPWGDS

AHNAK2

351

Q8IVF2
LWGASILKAGAGVPG

AHNAK2

5431

Q8IVF2
VAGWGRTGVLKPGSD

CMA1

146

P23946
PGPGGGSKDLLFWVA

CLEC14A

81

Q86T13
VSGPGGICLWNVLAG

CLRN2

131

A0PK11
GAAEEAAPPWALGLG

CNNM3

126

Q8NE01
PGGLGDWLLEVEFGQ

USP51

176

Q70EK9
AGALAWALGPAGGQA

VIPR1

16

P32241
LLLLWGLLPGTAAGG

MOXD1

6

Q6UVY6
GALFVWLLRGGPGDT

STBD1

16

O95210
SWGDVGVGGSLKAPV

STBD1

211

O95210
WRGVLGPLLVAGTAG

ROM1

96

Q03395
TGSGGPLLWETQLGL

TNFSF14

106

O43557
VGSEIAGGAGPGWVL

SLC39A7

406

Q92504
PGLALLWAVGLGSAA

SEMA3B

11

Q13214
GFGGSGIPKAWAGID

SPINT1

156

O43278
GGPGAGAAELLKAWQ

PHOX2A

241

O14813
SGPGLLEGFSGWAAL

SLC35A4

241

Q96G79
LGAAAFGPGSGPVWL

SCART1

836

Q4G0T1
AGLTWERNLPGAGVG

TACC2

1501

O95359
GGAGVPGHLWEGDLE

RHOXF2

81

Q9BQY4
LRSEPDGISLGGSWG

MPL

256

P40238
GPWGQGAAVKTGSEL

TET3

111

O43151
FKGSGHWLPAAGLAG

PRAG1

886

Q86YV5
GAGAAPKAGLSGLFW

SKOR2

441

Q2VWA4
RKPGWVVGLGTDGSA

ZNF862

686

O60290
ATSAPGLAWGPLVLG

LTBR

6

P36941
DPGLNTGGWNIAGRE

WDR59

796

Q6PJI9
GGIPGWQALLTAVGF

TTC28

1776

Q96AY4
VGVGLETLWGPGDGS

VWA5B2

856

Q8N398
LSSGPAPGGLSGLWE

ZNHIT2

86

Q9UHR6
LWGGQGSSVLLETGP

ZNF212

251

Q9UDV6
GGWTGPELSAFGELV

PLEKHG2

301

Q9H7P9
ALRAVWGGLAAPGAS

TARBP1

206

Q13395
ALGVEAWAAGQPDIG

ZNF746

201

Q6NUN9
PFVNWKGALGGLLTG

SLC5A12

431

Q1EHB4
VPGKEISALSWEGGG

WDR35

301

Q9P2L0
WGPGAAKSAVGTAIL

TFR2

436

Q9UP52
GEGGIFGPWSVSALL

SLC35E3

211

Q7Z769
VQGGSEAWGPGTLAA

TEX19

91

Q8NA77
EAWGPGTLAAAPEGL

TEX19

96

Q8NA77
QLEGGALGSWGSAPL

ZFTA

51

C9JLR9
GWGALREGGPISNAL

TMPRSS6

706

Q8IU80
SLGPLGKALVTGWEG

nan

96

Q6ZPA2
GFGVLGPEGQLVSWI

GLYATL2

201

Q8WU03
WEAEGLGLRVGAAGP

HECTD3

66

Q5T447
WALAAVALPGSGAEG

JMJD8

11

Q96S16
LLGAWAIPGGLGDRA

MZB1

11

Q8WU39
LTSLFGAWAGLGPGQ

GRIN2C

11

Q14957
WGVLLNSGIGEGAPR

GRIN1

611

Q05586