Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF729 ZNF726P1 RLF ZBTB10 ZNF521 ZNF737 ZNF808 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

2.48e-1814124325GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF729 ZNF726P1 ZBTB10 ZNF521 ZNF737 ZNF808 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

9.24e-1714594324GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF729 ZNF726P1 ZNF521 ZNF737 ZNF808 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

7.49e-1612444322GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF729 ZNF726P1 ZNF521 ZNF737 ZNF808 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

1.17e-1512714322GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ZNF729 ZBTB10 SP2 ZNF134 KLF12 ZNF217 ZEB1 ZNF99 ZEB2 ZNF572

1.17e-093204310GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZNF729 ZBTB10 SP2 ZNF134 KLF12 ZNF217 ZEB1 ZNF99 ZEB2 ZNF572

1.39e-093264310GO:0001217
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF729 RLF ZNF521 ZNF808 ZNF143 ZNF99 ZEB2

1.76e-04560437GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF729 RLF ZNF521 ZNF808 ZNF143 ZNF99 ZEB2

1.88e-04566437GO:0001216
GeneOntologyMolecularFunctionsnoRNA binding

IMP4 BMS1

2.43e-0334432GO:0030515
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

ZNF729 ZBTB10 SP2 ZNF134 KLF12 ZNF217 ZBTB38 ZEB1 RESF1 ZNF99 ZEB2 ZNF423 ZNF572

1.99e-0614134113GO:1902679
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

ZNF729 ZBTB10 SP2 ZNF134 KLF12 ZNF217 ZBTB38 ZEB1 ZNF99 ZEB2 ZNF423 ZNF572

1.13e-0513994112GO:0045892
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

ZNF729 ZBTB10 SP2 ZNF134 KLF12 ZNF217 ZEB1 ZNF99 ZEB2 ZNF572

3.03e-0510534110GO:0000122
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

ZNF729 RLF ZNF521 ZNF808 KLF12 ZBTB38 ZNF143 ZEB1 ZNF99 CDK12 ZEB2

6.02e-0513904111GO:0045944
DomainZINC_FINGER_C2H2_2

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 BNC2 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

2.52e-247754225PS50157
DomainZINC_FINGER_C2H2_1

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 BNC2 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

2.69e-247774225PS00028
DomainZnf_C2H2

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 BNC2 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

6.44e-248054225IPR007087
DomainZnF_C2H2

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 BNC2 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

7.05e-248084225SM00355
Domain-

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

1.27e-2267942233.30.160.60
DomainZnf_C2H2-like

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 BNC2 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

1.57e-227964224IPR015880
Domainzf-C2H2

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 BNC2 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZNF90 ZNF99 ZNF684 ZNF678 ZNF257 ZNF423 ZNF572 ZNF114

2.01e-226934223PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

2.08e-226944223IPR013087
Domainzf-C2H2_6

ZNF729 ZNF521 ZNF737 ZNF808 ZNF880 ZNF90 ZNF99 ZNF684 ZNF423 ZNF572 ZNF114

6.86e-113144211PF13912
DomainKRAB

ZNF729 ZNF737 ZNF808 ZNF880 ZNF90 ZNF99 ZNF684 ZNF257 ZNF114

8.06e-08358429PS50805
DomainKRAB

ZNF729 ZNF737 ZNF808 ZNF880 ZNF90 ZNF99 ZNF684 ZNF257 ZNF114

8.06e-08358429PF01352
DomainKRAB

ZNF729 ZNF737 ZNF808 ZNF880 ZNF90 ZNF99 ZNF684 ZNF257 ZNF114

1.04e-07369429SM00349
DomainKRAB

ZNF729 ZNF737 ZNF808 ZNF880 ZNF90 ZNF99 ZNF684 ZNF257 ZNF114

1.07e-07370429IPR001909
DomainDi19_Zn_binding_dom

ZEB1 ZEB2

1.03e-047422IPR008598
Domainzf-Di19

ZEB1 ZEB2

1.03e-047422PF05605
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF729 ZNF521 ZNF737 ZNF740 ZNF143 ZNF99 ZNF684 ZNF678 ZNF257 CDK12 CNOT3 ZNF114

8.28e-0613872912M734
PathwayREACTOME_FORMATION_OF_THE_POSTERIOR_NEURAL_PLATE

ZNF521 ZEB2

1.82e-0410292M48036
PathwayREACTOME_FORMATION_OF_THE_ANTERIOR_NEURAL_PLATE

ZNF521 ZEB2

2.22e-0411292M48031
PathwayREACTOME_RRNA_PROCESSING

GNL3 NOL12 IMP4 BMS1

7.76e-04205294M27685
Pubmed

Human transcription factor protein interaction networks.

MRPS15 RLF ZBTB10 ZNF521 SP2 KLF12 ZNF217 ZNF143 ZEB1 RESF1 PGAM5 ZEB2 CNOT3 GNL3 BMS1

7.65e-111429431535140242
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF737 ZNF90 ZNF99 ZNF114

3.65e-09164348467795
Pubmed

Interaction network of human early embryonic transcription factors.

RLF ZNF521 ZNF217 ZEB1 RESF1 ZEB2 ZNF423

2.37e-0735143738297188
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF729 BNC2 SP2 ZNF740 KLF12 ZNF143 ZEB1 ZNF99 ZNF423

5.24e-0780843920412781
Pubmed

Investigation of primary microcephaly in Bushehr province of Iran: novel STIL and ASPM mutations.

ASPM STIL

1.49e-06243222989186
Pubmed

The Zeb proteins δEF1 and Sip1 may have distinct functions in lens cells following cataract surgery.

ZEB1 ZEB2

1.49e-06243225082886
Pubmed

The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.

ZEB1 ZEB2

1.49e-06243237948583
Pubmed

ZEBs: Novel Players in Immune Cell Development and Function.

ZEB1 ZEB2

1.49e-06243230956067
Pubmed

The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2.

ZEB1 ZEB2

1.49e-06243237819755
Pubmed

Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis.

ZEB1 ZEB2

1.49e-06243228416756
Pubmed

The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer.

ZEB1 ZEB2

1.49e-06243228133913
Pubmed

Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway.

ZEB1 ZEB2

1.49e-06243220025777
Pubmed

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.

ZEB1 ZEB2

1.49e-06243220424117
Pubmed

Zfhx1a and Zfhx1b mRNAs have non-overlapping expression domains during chick and mouse midgestation limb development.

ZEB1 ZEB2

1.49e-06243212609600
Pubmed

Expression of miRNAs and ZEB1 and ZEB2 correlates with histopathological grade in papillary urothelial tumors of the urinary bladder.

ZEB1 ZEB2

1.49e-06243224306957
Pubmed

Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein.

ZNF521 ZNF423

1.49e-06243212393497
Pubmed

Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner.

ZEB1 ZEB2

1.49e-06243220375168
Pubmed

Prognostic Significance of Zinc Finger E-Box-Binding Homeobox Family in Glioblastoma.

ZEB1 ZEB2

1.49e-06243229476046
Pubmed

Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer.

ZEB1 ZEB2

1.49e-06243222213144
Pubmed

TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.

ZEB1 ZEB2

1.49e-06243221747944
Pubmed

Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development.

ZEB1 ZEB2

1.49e-06243216957952
Pubmed

Genome-wide analysis of endogenously expressed ZEB2 binding sites reveals inverse correlations between ZEB2 and GalNAc-transferase GALNT3 in human tumors.

GALNT3 ZEB2

1.49e-06243229516288
Pubmed

Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.

ZEB1 ZEB2

1.49e-06243234550965
Pubmed

Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer.

ZEB1 ZEB2

1.49e-06243222892238
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF737 ZNF90 ZNF684 ZNF678 ZNF257

2.96e-0618143537372979
Pubmed

The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins.

ZEB1 ZEB2

4.48e-06343226823172
Pubmed

Vimentin, zeb1 and Sip1 are up-regulated in triple-negative and basal-like breast cancers: association with an aggressive tumour phenotype.

ZEB1 ZEB2

4.48e-06343223412770
Pubmed

A miRNA signature associated with human metastatic medullary thyroid carcinoma.

ZEB1 ZEB2

4.48e-06343224127332
Pubmed

A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

ZEB1 ZEB2

4.48e-06343221890822
Pubmed

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.

ZEB1 ZEB2

4.48e-06343218376396
Pubmed

TCF4 promotes colorectal cancer drug resistance and stemness via regulating ZEB1/ZEB2 expression.

ZEB1 ZEB2

4.48e-06343231933004
Pubmed

p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.

ZEB1 ZEB2

4.48e-06343221518799
Pubmed

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2.

ZEB1 ZEB2

4.48e-06343218411277
Pubmed

miR-139-5p suppresses cancer cell migration and invasion through targeting ZEB1 and ZEB2 in GBM.

ZEB1 ZEB2

4.48e-06343225833697
Pubmed

Down-regulation of miR-144 promotes thyroid cancer cell invasion by targeting ZEB1 and ZEB2.

ZEB1 ZEB2

4.48e-06343224968735
Pubmed

Src promotes EGF-induced epithelial-to-mesenchymal transition and migration in gastric cancer cells by upregulating ZEB1 and ZEB2 through AKT.

ZEB1 ZEB2

4.48e-06343229052277
Pubmed

Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch.

ZNF521 ZNF423

4.48e-06343224891617
Pubmed

Expression of miR-9 and miR-200c, ZEB1, ZEB2 and E-cadherin in Non-Small Cell Lung Cancers in Iran.

ZEB1 ZEB2

4.48e-06343231244281
Pubmed

miR-144-3p inhibited the growth, metastasis and epithelial-mesenchymal transition of colorectal adenocarcinoma by targeting ZEB1/2.

ZEB1 ZEB2

4.48e-06343234226299
Pubmed

miR-139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2.

ZEB1 ZEB2

4.48e-06343226022123
Pubmed

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.

ZEB1 ZEB2

4.48e-06343221411626
Pubmed

BMP4 signaling mediates Zeb family in developing mouse tooth.

ZEB1 ZEB2

4.48e-06343222350174
Pubmed

MiR-200c suppresses TGF-β signaling and counteracts trastuzumab resistance and metastasis by targeting ZNF217 and ZEB1 in breast cancer.

ZNF217 ZEB1

4.48e-06343224615544
Pubmed

Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta.

ZEB1 ZEB2

4.48e-06343217615296
Pubmed

Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2.

ZEB1 ZEB2

4.48e-06343224165969
Pubmed

miR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2.

ZEB1 ZEB2

4.48e-06343226556542
Pubmed

ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies.

ZNF521 ZNF423

4.48e-06343226788497
Pubmed

miR-200c inhibits TGF-β-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer.

ZEB1 ZEB2

4.48e-06343229302045
Pubmed

Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression.

ZEB1 ZEB2

8.94e-06443225301070
Pubmed

Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells.

ZEB1 ZEB2

8.94e-06443228247944
Pubmed

Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants.

ZEB1 ZEB2

8.94e-06443216598713
Pubmed

miR-200b regulates cell migration via Zeb family during mouse palate development.

ZEB1 ZEB2

8.94e-06443222261924
Pubmed

MiR-525-5p Repressed Metastasis and Anoikis Resistance in Cervical Cancer via Blocking UBE2C/ZEB1/2 Signal Axis.

ZEB1 ZEB2

8.94e-06443231679088
Pubmed

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

ZEB1 ZEB2

8.94e-06443217360662
Pubmed

miR-200b/c attenuates lipopolysaccharide-induced early pulmonary fibrosis by targeting ZEB1/2 via p38 MAPK and TGF-β/smad3 signaling pathways.

ZEB1 ZEB2

8.94e-06443229200203
Pubmed

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.

ZEB1 ZEB2

8.94e-06443221079000
Pubmed

The MicroRNA 29 Family Promotes Type II Cell Differentiation in Developing Lung.

ZEB1 ZEB2

8.94e-06443227215389
Pubmed

Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.

ZEB1 ZEB2

8.94e-06443223381389
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RLF ZBTB10 ZNF217 ZEB1 RESF1 ZEB2

1.22e-0541843634709266
Pubmed

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition.

ZEB1 ZEB2

1.49e-05543218829540
Pubmed

Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells.

ZNF521 ZNF423

1.49e-05543214630787
Pubmed

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.

ZEB1 ZEB2

1.49e-05543229449309
Pubmed

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins.

ZEB1 ZEB2

1.49e-05543212743039
Pubmed

Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway.

ZEB1 ZEB2

1.49e-05543212743038
Pubmed

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression.

ZEB1 ZEB2

1.49e-05543219651985
Pubmed

miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5.

ZEB1 ZEB2

2.23e-05643222685266
Pubmed

Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.

ZEB1 ZEB2

2.23e-05643212161443
Pubmed

A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration.

ZEB1 ZEB2

4.16e-05843230271956
Pubmed

Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin.

ZEB1 ZEB2

4.16e-05843216061479
Pubmed

Interaction of ZEB and histone deacetylase with the PLDLS-binding cleft region of monomeric C-terminal binding protein 2.

ZNF217 ZEB1

4.16e-05843219754958
Pubmed

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors.

ZEB1 ZEB2

4.16e-05843225460509
Pubmed

Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin.

ZEB1 ZEB2

4.16e-05843212714599
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

MRPS15 ZNF521 ZBTB38 CDK12 PGAM5 ZNF423 NOL12 BMS1

4.71e-05108243838697112
Pubmed

Location of the 9257 and ataxia mutations on mouse chromosome 18.

ZNF521 ZEB1

5.35e-0594328662222
Pubmed

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.

ZEB1 ZEB2

5.35e-05943224769727
Pubmed

Tagging genes with cassette-exchange sites.

BNC2 RESF1 CDK12 GNL3 ZNF423

5.74e-0533543515741177
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF729 ZNF99

6.68e-051043218588511
Pubmed

Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin.

ZEB1 ZEB2

6.68e-051043234193422
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF729 ZNF99

8.15e-051143215469996
Pubmed

Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex.

ZNF217 ZEB1

9.78e-051243217967884
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF729 ZNF99

1.15e-041343219850934
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

SP2 ZNF217 ZEB1 RESF1 ZEB2

1.29e-0439843535016035
Pubmed

Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis.

ZEB1 ZEB2

1.35e-041443226324903
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF729 ZNF99

1.55e-041543215885501
Pubmed

Deletion of Yy1 in mouse lung epithelium unveils molecular mechanisms governing pleuropulmonary blastoma pathogenesis.

ZEB1 ZEB2

1.55e-041543233158935
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

MRPS15 SP2 CDK12 GNL3 NOL12

1.60e-0441743536537216
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

MRPS15 ASPM RLF CDK12 PGAM5 GNL3 BMS1

1.73e-0497143733306668
Pubmed

TBX1 targets the miR-200-ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties.

ZEB1 ZEB2

1.77e-041643236418889
Pubmed

Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis.

ZNF521 ZNF423

1.77e-041643217521568
Pubmed

Zeb family members and boundary cap cells underlie developmental plasticity of sensory nociceptive neurons.

ZEB1 ZEB2

1.77e-041643225942625
Pubmed

Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

ASPM STIL

1.77e-041643220301772
Pubmed

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2.

ZEB1 ZEB2

2.01e-041743231171776
Pubmed

Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.

ZNF134 ZNF143

2.01e-04174327557990
Pubmed

PDGFRα controls the balance of stromal and adipogenic cells during adipose tissue organogenesis.

ZNF521 ZNF423

2.52e-041943228049691
Pubmed

Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study.

ZBTB38 ZNF678

2.80e-042043220846217
Pubmed

Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development.

ZEB1 ZEB2

3.09e-042143224161570
Pubmed

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.

PKHD1 ZEB2

3.09e-042143227591083
Pubmed

Genome-wide association analysis identifies 20 loci that influence adult height.

ZBTB38 ZNF678

3.40e-042243218391952
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ASPM ZBTB10 ZNF740 RESF1 PGAM5 GNL3 NOL12

4.03e-04111643731753913
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

ZBTB10 ZNF217 ZEB2

4.05e-0411643330804394
InteractionFEV interactions

RLF ZBTB10 ZNF521 SP2 ZNF217 ZNF143 ZEB1 ZEB2

8.12e-09203428int:FEV
InteractionNFIX interactions

RLF ZBTB10 ZNF521 ZNF217 ZNF143 ZEB1 ZEB2

4.05e-07227427int:NFIX
InteractionKLF16 interactions

RLF ZBTB10 ZNF521 ZBTB38 ZNF143 PGAM5 ZEB2 GNL3

2.31e-06425428int:KLF16
InteractionKLF12 interactions

MRPS15 KLF12 ZNF217 ZEB1 ZEB2 GNL3

2.90e-06194426int:KLF12
InteractionMBD3L2 interactions

ZBTB10 ZNF521 ZNF423

8.49e-0541423int:MBD3L2
InteractionKLF3 interactions

RLF ZNF217 ZEB1 ZEB2 ZNF423

1.07e-04228425int:KLF3
InteractionELK3 interactions

ZBTB10 SP2 ZNF217 ZEB2

1.12e-04120424int:ELK3
InteractionMYB interactions

RLF ZBTB10 ZEB1 ZEB2

1.67e-04133424int:MYB
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF729 ZNF737 ZNF90 ZNF99 ZNF257

1.08e-07122435chr19p12
Cytoband19p12

ZNF729 ZNF737 ZNF90 ZNF99

1.61e-069043419p12
Cytoband1p32

RLF STIL

2.96e-04274321p32
Cytoband19q13.41

ZNF808 ZNF880

2.46e-037843219q13.41
Cytoband19q13.4

ZNF134 CNOT3

2.52e-037943219q13.4
CytobandEnsembl 112 genes in cytogenetic band chr1p34

MRPS15 RLF ZNF684

2.65e-03294433chr1p34
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF808 ZNF134 ZNF880 CNOT3 ZNF114

4.97e-031192435chr19q13
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF729 RLF ZBTB10 ZNF521 ZNF737 ZNF808 BNC2 SP2 ZNF134 ZNF740 KLF12 ZNF880 ZNF217 ZBTB38 ZNF143 ZEB1 ZNF90 ZNF99 ZNF684 ZNF678 ZNF257 ZEB2 ZNF423 ZNF572 ZNF114

1.62e-29718322528
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZEB1 ZEB2

3.14e-0415322529
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB10 ZBTB38

2.34e-02134322861
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500

ASPM PKHD1 RLF BNC2 KLF12 RESF1 ZEB2

1.30e-05404427gudmap_developingGonad_e18.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#5_top-relative-expression-ranked_500

BNC2 KLF12 RESF1 ZEB2

3.12e-0591424gudmap_developingGonad_e14.5_ epididymis_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

ASPM RLF BNC2 KLF12 RESF1 ZEB2

1.22e-04397426gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

ASPM RLF BNC2 KLF12 RESF1 CDK12 ZEB2 CNOT3

1.36e-04790428gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500

ASPM RLF BNC2 KLF12 RESF1 ZEB2

1.38e-04406426gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

ASPM PKHD1 RLF BNC2 KLF12 RESF1 ZEB2 CNOT3

1.47e-04799428gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

ASPM PKHD1 RLF BNC2 KLF12 RESF1 ZEB2 CNOT3

1.50e-04801428gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500

ASPM RLF BNC2 KLF12 RESF1 ZEB2

1.51e-04413426gudmap_developingGonad_e14.5_ epididymis_500
ToppCellLeuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, Lineage and Cell Type

ZBTB10 TEKT4 ZEB1 GALNT3

1.59e-0516142451b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM SP2 STIL ZEB2

1.75e-0516542496f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF521 BNC2 ZEB1 ZNF99

1.97e-051704241a568efcff9c39b3f709b55a05d24710450a2657
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF521 BNC2 ZEB1 ZNF99

1.97e-0517042466d41d794790e621d72ac37af995510537103c9c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF729 ASPM STIL ZNF257

2.57e-05182424336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZEB1 ZNF423

2.86e-05187424e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF729 ASPM STIL ZNF257

2.86e-05187424057569c9437219ecc396aa6e673b1178a2273837
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNF521 BNC2 ZEB1 ZNF423

2.98e-051894247346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZEB1 ZNF423

3.04e-051904247dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellCV-Moderate-0|Moderate / Virus stimulation, Condition and Cluster

KLF12 ZBTB38 RESF1 ZEB2

3.10e-051914246776bcc4c1915f0c1062002ff7746f20ceb725f4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRPS15 ASPM GNL3 IMP4

3.10e-05191424b6cc0a9ced40ce5f80065d24d5bc20e3838a7682
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZEB1 NLGN4Y

3.17e-0519242472881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZEB1 ZNF423

3.17e-05192424d21f0f577156f17c899b08871046a26b88aea011
ToppCellSepsis-Leuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, condition lineage and cell class

ZBTB10 TEKT4 ZEB1 GALNT3

3.64e-05199424a2f154b15087803958a656d2a41b6d83fd37b32f
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF521 BNC2 ZEB1 ZEB2

3.72e-05200424b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF521 BNC2 ZEB1 ZEB2

3.72e-05200424c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF521 BNC2 ZEB1 ZEB2

3.72e-0520042474e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF521 BNC2 ZEB1 ZEB2

3.72e-0520042458b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellPBMC-Severe-cDC_2|Severe / Compartment, Disease Groups and Clusters

TEKT4 ZNF257 ZNF572

3.80e-05694230fab02d29408415d3aa1f42a55a2e37b458c4030
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF880 ZNF423 IPMK

2.84e-04136423edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF880 ZNF423 IPMK

2.84e-0413642303e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCellDividing_Macrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ASPM ZNF737 ZNF684

3.94e-04152423e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|World / disease group, cell group and cell class (v2)

ZEB1 ZNF257 GNL3

3.94e-04152423f944743f40ff6ed3a7a096dd53e12d3526c67c4d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 ZEB1 ZNF423

4.25e-04156423f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCellCOVID-19-APC-like-Alveolar_macrophages|COVID-19 / group, cell type (main and fine annotations)

SP2 IPMK IMP4

4.25e-04156423735ade77cfa16b9386a0c7ec2bd14bd2e78a51ad
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF90 RESF1 ZNF114

4.49e-04159423bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RLF ZNF217 ZEB2

4.58e-041604236ed37d1fd0304932319d6b942502404115ff36a7
ToppCell367C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ASPM ZNF99 ZNF423

4.66e-04161423c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell367C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ASPM ZNF99 ZNF423

4.66e-041614239864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZBTB10 KLF12 ZEB1

4.75e-0416242380317c4253bf8e897782e562f29835f181c65b98
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 ZEB1 ZNF423

4.83e-0416342373c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF729 ASPM STIL

5.01e-04165423eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ZNF521 ZEB1 ZNF423

5.09e-04166423c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GALNT3 ZNF684 PGAM5

5.27e-0416842394cded2e953c0970bf2f3dbe0ce46bd77a5ed8c7
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

ZEB1 ZNF257 ZNF423

5.27e-041684238c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

ZNF521 ZEB1 ZNF257

5.37e-04169423e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCellControl-T_cells-Tregs|Control / group, cell type (main and fine annotations)

KLF12 ZEB1 RESF1

5.37e-04169423e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

ASPM RLF ZNF572

5.37e-0416942302fa66a91b8bd2bf971aec4f5ec58318b5bfdf14
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM STIL IPMK

5.37e-041694234db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

ZNF521 BNC2 ZEB2

5.37e-04169423fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

ZNF521 BNC2 ZEB2

5.46e-04170423c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ASPM STIL ZEB2

5.55e-0417142352fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ASPM STIL ZEB2

5.55e-04171423e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

ZNF521 ZEB1 ZNF423

5.65e-04172423c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel|Adult / Lineage, Cell type, age group and donor

ZNF134 NLGN4Y ZNF423

5.65e-04172423ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZEB1

5.74e-041734231f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM ZNF521 STIL

5.84e-0417442372df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM ZNF521 STIL

5.84e-04174423c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

ZNF521 ZEB1 ZNF423

5.84e-041744232dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

ZNF880 ZEB1 ZNF423

5.94e-041754230a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF12 ZBTB38 ZNF572

6.04e-041764235914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

BNC2 GALNT3 ZEB2

6.04e-04176423473c45a381ca109207d66ed1635668b391ea0e1f
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

ZNF521 ZEB1 ZNF423

6.04e-04176423043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF521 ZNF423 IPMK

6.14e-041774231921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

ZNF521 ZEB1 ZNF423

6.24e-04178423c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 ZEB1 ZNF423

6.34e-041794238f9e538c822940785130297712b75131812a4603
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASPM ZNF217 STIL

6.45e-04180423271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZNF423

6.45e-0418042327e8bbee388e64dd79d70b160b76d45b1f398006
ToppCellCOVID-19-kidney-Mito-rich_EC|kidney / Disease (COVID-19 only), tissue and cell type

ZNF521 ZEB1 ZNF423

6.76e-041834233c4153479fc4ab2d073d92cee120480015555914
ToppCellCTRL-Myeloid-cDC|CTRL / Disease state, Lineage and Cell class

ZBTB10 KLF12 ZEB1

6.76e-0418342320c4d16de7e090df3556a4458f783383a26871b6
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNF521 ZEB1 ZNF423

6.76e-04183423ff95382cfed592190d0636d2b750328471f82e0d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 ZEB1 ZNF423

6.87e-04184423688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM STIL IPMK

6.87e-0418442316aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PKHD1 TEKT4 GALNT3

6.87e-04184423fa4915b0498f3069fd5ef497286445528f75187e
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZEB1

6.87e-041844232b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF521 ZEB1 ZNF423

6.98e-04185423f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BNC2 ZEB1 ZEB2

6.98e-041854239f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RLF ZBTB10 RESF1

6.98e-04185423e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BNC2 ZEB1 ZEB2

6.98e-041854231ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZEB1

6.98e-04185423fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellControl-Myeloid-DC_Mature|Myeloid / Disease state, Lineage and Cell class

ZBTB10 KLF12 ZEB1

7.09e-04186423e9e58c5871b4966cd3586b611703e21af8df6360
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM ZBTB38 STIL

7.09e-041864234ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM ZBTB38 STIL

7.09e-0418642315ab6666748a641226e42e6ca6eeaf186a501c95
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BNC2 ZEB1 ZEB2

7.09e-041864237def03dd856b765bd3f493288641981c4f7fd26e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 BNC2 ZEB1

7.20e-04187423c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BNC2 ZEB1 ZEB2

7.20e-0418742313731298bc562ec29582f5da1b4c97261284f6f1
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK|GI_small-bowel / Manually curated celltypes from each tissue

ASPM STIL ZNF572

7.20e-04187423265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

ZNF521 BNC2 ZEB1

7.20e-04187423bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

ZNF521 ZEB1 ZNF423

7.20e-041874231e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF521 ZEB1 ZNF423

7.20e-041874232d20193a6cacdfa4877457c97b0077408942186c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 BNC2 ZEB1

7.31e-04188423af740fa78542438fdff627ea1f74f4eee43316be
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

ZNF521 ZEB1 ZNF423

7.31e-04188423d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellCOPD-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

BNC2 ZEB1 ZEB2

7.31e-04188423159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KLF12 ZEB1 RESF1

7.42e-04189423df30478b288084a1bd48f660409dcc784040897c
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

ZNF521 BNC2 ZEB1

7.42e-041894233922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

ZNF521 BNC2 ZEB1

7.42e-0418942344e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellIPF-Myeloid-DC_Mature|Myeloid / Disease state, Lineage and Cell class

ZBTB10 KLF12 ZEB1

7.42e-0418942349e67d298d045f29136919b7d9971b6502b0efaa
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PKHD1 TEKT4 GALNT3

7.42e-04189423c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell(1)_T_cells-(1)_T_CD8_gd|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

BNC2 ZBTB38 ZEB2

7.54e-04190423268772d2adff34f7175b8474e95b67fd96dc1234
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

ZNF521 ZEB1 ZNF423

7.54e-0419042391bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNF521 ZEB1 ZNF423

7.54e-041904231caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLF12 RESF1 ZEB2

7.54e-04190423d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ASPM ZEB1 STIL

7.54e-04190423e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD8-Tem/emra_CD8|bone_marrow / Manually curated celltypes from each tissue

ZBTB38 RESF1 ZEB2

7.65e-04191423db7b8f8826bf19d6eeee14319570a9e6e99ab2cb
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like-IPCs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

KLF12 ZEB1 ZNF423

7.65e-04191423e4c1c533771b582e21683dbec6f93a558d865e00
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

KLF12 ZEB1 RESF1

7.65e-04191423c7be771543089fc94e5c62fd22f745189642aec3
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

BNC2 ZEB1 NLGN4Y

7.65e-04191423d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellAdult-Immune-T_lymphocyte-D175|Adult / Lineage, Cell type, age group and donor

KLF12 ZEB1 RESF1

7.65e-041914230b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ASPM PKHD1 STIL

7.65e-0419142339220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like|3_mon / Sample Type, Dataset, Time_group, and Cell type.

KLF12 ZEB1 ZNF423

7.65e-0419142348cffb55c71bb8b34e926fc461fcd345ce43ea00
Diseaserheumatic heart disease (biomarker_via_orthology)

ZEB1 ZEB2

1.29e-0412422DOID:0050827 (biomarker_via_orthology)
Diseasebody fat distribution

BNC2 ZBTB38 ZNF678 GNL3

1.95e-04202424EFO_0004341
DiseaseAutosomal recessive primary microcephaly

ASPM STIL

2.05e-0415422cv:C3711387
DiseasePrimary microcephaly

ASPM STIL

4.49e-0422422C0431350
DiseaseAutosomal Recessive Primary Microcephaly

ASPM STIL

4.49e-0422422C3711387
Diseaseovarian neoplasm

BNC2 ZEB1 CDK12

9.24e-04134423C0919267
Diseasemicrocephaly (implicated_via_orthology)

ASPM STIL

9.55e-0432422DOID:10907 (implicated_via_orthology)
DiseaseMalignant neoplasm of ovary

BNC2 ZEB1 CDK12

9.85e-04137423C1140680
Diseasehair color

PKHD1 BNC2 SP2 ZBTB38

9.88e-04311424EFO_0003924
Diseasecutaneous squamous cell carcinoma

BNC2 ZNF143

1.02e-0333422EFO_1001927
Diseasecannabis dependence measurement

PKHD1 ZEB1

2.14e-0348422EFO_0008457
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

STIL CNOT3

2.60e-0353422C1961099
Diseasesusceptibility to common cold measurement

SWT1 ZNF423

2.70e-0354422EFO_0008417
Diseasecolorectal health

KLF12 ZNF880 IPMK

2.94e-03201423EFO_0008460
Diseasemean platelet volume

ZBTB10 KLF12 ZNF217 ZBTB38 STIL CDK12

3.04e-031020426EFO_0004584
DiseaseFamilial Nonmedullary Thyroid Cancer

ZEB1 ZEB2

3.43e-0361422C3501844
DiseaseNonmedullary Thyroid Carcinoma

ZEB1 ZEB2

3.43e-0361422C3501843
DiseaseEczema, allergic rhinitis

BNC2 ZNF217 ZBTB38

3.55e-03215423EFO_0005854, HP_0000964
DiseaseTesticular Germ Cell Tumor

RESF1 ZNF257

4.88e-0373422EFO_1000566
Diseaseskin neoplasm

ZBTB10 BNC2

5.01e-0374422EFO_0004198
Diseasebalding measurement

ZNF521 KLF12 ZBTB38 ZNF423 ZNF572

5.15e-03792425EFO_0007825
Diseasesudden cardiac arrest

PKHD1 KLF12

6.26e-0383422EFO_0004278
DiseasePapillary thyroid carcinoma

ZEB1 ZEB2

6.70e-0386422C0238463
Diseasephysical activity

PKHD1 ZNF521

7.01e-0388422EFO_0003940
DiseaseUterine leiomyoma

ZEB1 ZNF257

7.48e-0391422HP_0000131
Diseasered blood cell density measurement

PKHD1 KLF12 ZNF217 CDK12 ZEB2

7.96e-03880425EFO_0007978

Protein segments in the cluster

PeptideGeneStartEntry
HRLVSKHKRHKSKHS

CDK12

36

Q9NYV4
LKIHYNAVHLKIKHR

BNC2

456

Q6ZN30
SFHRTQDLKTKKHHI

BMS1

56

Q14692
LIQRKYRAHLCTKHH

ASPM

2291

Q8IZT6
IEGLKRHIEKHRYHV

CNOT3

166

O75175
ASLHAHSRKKVKRKH

NOL12

166

Q9UGY1
HHVYKKTDHRNVELT

IMP4

231

Q96G21
HYKAKATRHIFLIRH

PGAM5

91

Q96HS1
HRKIYTKKHHSQTSL

IPMK

321

Q8NFU5
LYYKKDKRRHETHRH

NLGN4Y

696

Q8NFZ3
RLVKLHIKRHYHKKF

GALNT3

6

Q14435
HKRYKIQKKVREHHR

GNL3

16

Q9BVP2
KVYTKSSHLKAHRRT

KLF12

326

Q9Y4X4
EHLEKHRKDKAHKRY

MRPS15

141

P82914
NHKRKKLRFHEVTFH

RESF1

1291

Q9HCM1
DARYKLHHHLHKTLR

TEKT4

301

Q8WW24
VKGHHVRIYERLKHR

PKHD1

2916

P08F94
FTYKRTVHEWKRKHH

SWT1

291

Q5T5J6
KRHRPQHYKHEDAKE

ZNF572

56

Q7Z3I7
VYHTKKKTHHSRLVD

STIL

976

Q15468
KHFSALRKHKIIHTG

ZNF99

771

A8MXY4
KFHFIRHEKNHTRKK

ZNF684

171

Q5T5D7
HKLYLKKHERIHTGE

ZNF880

531

Q6PDB4
LTRHKRIHTGEKRYK

ZNF678

476

Q5SXM1
KLYTTAHHLKVHERS

ZNF143

246

P52747
FTRKTHLRIHYKNKH

RLF

1181

Q13129
RSDHLTKHYKTHLVT

SP2

596

Q02086
RDRHIKLHTGDKKYH

ZNF521

161

Q96K83
FSRKSHLKRHRIIHT

ZNF808

856

Q8N4W9
RFTSLKEHIKYRHEK

ZEB1

181

P37275
LTSHKRIHTGEKRYK

ZNF90

216

Q03938
TYHQLVLHSRVHKKD

ZNF217

386

O75362
KTSLRYHLERHHKEK

ZNF217

511

O75362
RREHVKRHSLVHKKD

ZBTB10

761

Q96DT7
RDRHIKLHTGDKKYH

ZNF423

181

Q2M1K9
LKIHERIHTGEKRYH

ZBTB38

1081

Q8NAP3
KRLTSLKEHIKYRHE

ZEB2

221

O60315
FKYKHHLKEHLRIHS

ZEB2

291

O60315
KYHLERHKRVHSGEK

ZNF740

141

Q8NDX6
TLTKHKRIHTRGKHY

ZNF726P1

116

Q15940
GHKYTLIKHQRIHTE

ZNF134

326

P52741
HFSALRKHKIIHTGK

ZNF729

331

A6NN14
FKHFSALRKHKVIHT

ZNF729

581

A6NN14
KHFSALRKHKVIHTG

ZNF729

1086

A6NN14
FRYSLHLNKHLRKHV

ZNF114

341

Q8NC26
HLTKHKRIHTREKAY

ZNF257

386

Q9Y2Q1
LTTHKRIHTGEKRYK

ZNF737

216

O75373