Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	channel activity	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ SLC1A4 RHCE RHD TPCN1 KCNH6 SLC9C1 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H ATP5F1B	2.10e-08	525	137	18	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ SLC1A4 RHCE RHD TPCN1 KCNH6 SLC9C1 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H ATP5F1B	2.16e-08	526	137	18	GO:0022803
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	KCNH7 TRPC1 TRPC6 ABCC9 ADAMTS8 PKDREJ SLC1A4 RHCE RHD TPCN1 KCNH6 SLC9B1 SLC9C1 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H SLC4A4 ATP5F1B	5.08e-08	758	137	21	GO:0015318
GeneOntologyMolecularFunction	monoatomic cation channel activity	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ TPCN1 KCNH6 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H ATP5F1B	1.05e-07	343	137	14	GO:0005261
GeneOntologyMolecularFunction	monoatomic ion channel activity	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ SLC1A4 TPCN1 KCNH6 SLC9C1 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H ATP5F1B	1.08e-07	459	137	16	GO:0005216
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ RHCE RHD TPCN1 KCNH6 SLC9B1 SLC9C1 KCNH2 SCN2A PKD2 CACNA1I CACNA1H SLC4A4 ATP5F1B	2.99e-07	627	137	18	GO:0022890
GeneOntologyMolecularFunction	voltage-gated channel activity	KCNH7 ABCC9 TPCN1 KCNH6 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H	5.77e-07	184	137	10	GO:0022832
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ TPCN1 KCNH6 SLC9B1 SLC9C1 KCNH2 SCN2A PKD2 CACNA1I CACNA1H SLC4A4	7.41e-07	465	137	15	GO:0046873
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	TPCN1 SCN2A PKD2 CACNA1I CACNA1H	8.28e-07	26	137	5	GO:0005248
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ TPCN1 KCNH6 SLC9B1 SLC9C1 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H SLC4A4 ATP5F1B	3.11e-06	664	137	17	GO:0008324
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	KCNH7 ABCC9 KCNH6 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H	4.69e-06	182	137	9	GO:0005244
GeneOntologyMolecularFunction	transporter activity	ATP8B3 KCNH7 TRPC1 TRPC6 ABCC9 ADAMTS8 PKDREJ SLC1A4 ATP10D RHCE RHD TPCN1 KCNH6 SLC9B1 SLC9C1 KCNH2 ANO6 SCN2A PKD2 SLC35F6 CACNA1I CACNA1H SLC4A4 ATP5F1B	6.92e-06	1289	137	24	GO:0005215
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ SLC1A4 TPCN1 KCNH6 SLC9B1 SLC9C1 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H SLC4A4 ATP5F1B	8.29e-06	793	137	18	GO:0015075
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	ARHGAP32 SGSM1 ARHGEF28 MYCBP2 NGB ARHGAP26 ARHGEF12 ARHGAP6 ASAP2 NF1 EGF ARHGEF2 DOCK6 IQGAP3	1.06e-05	507	137	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	ARHGAP32 SGSM1 ARHGEF28 MYCBP2 NGB ARHGAP26 ARHGEF12 ARHGAP6 ASAP2 NF1 EGF ARHGEF2 DOCK6 IQGAP3	1.06e-05	507	137	14	GO:0030695
GeneOntologyMolecularFunction	transmembrane transporter activity	KCNH7 TRPC1 TRPC6 ABCC9 ADAMTS8 PKDREJ SLC1A4 RHCE RHD TPCN1 KCNH6 SLC9B1 SLC9C1 KCNH2 ANO6 SCN2A PKD2 SLC35F6 CACNA1I CACNA1H SLC4A4 ATP5F1B	1.73e-05	1180	137	22	GO:0022857
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	TPCN1 SLC9B1 SLC9C1 SCN2A PKD2 CACNA1I CACNA1H SLC4A4	2.40e-05	171	137	8	GO:0015081
GeneOntologyMolecularFunction	sodium channel activity	TPCN1 SCN2A PKD2 CACNA1I CACNA1H	2.83e-05	52	137	5	GO:0005272
GeneOntologyMolecularFunction	calcium channel activity	TRPC1 TRPC6 PKDREJ TPCN1 PKD2 CACNA1I CACNA1H	3.06e-05	129	137	7	GO:0005262
GeneOntologyMolecularFunction	inward rectifier potassium channel activity	KCNH7 ABCC9 KCNH6 KCNH2	3.82e-05	28	137	4	GO:0005242
GeneOntologyMolecularFunction	neuropeptide Y receptor activity	QRFPR NPY4R2 NPY4R	5.01e-05	11	137	3	GO:0004983
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	KCNH7 ABCC9 TPCN1 KCNH6 KCNH2 ANO6 PKD2	5.16e-05	140	137	7	GO:0099094
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPC1 TRPC6 PKDREJ TPCN1 PKD2 CACNA1I CACNA1H	8.33e-05	151	137	7	GO:0015085
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	KCNH7 ABCC9 KCNH6 KCNH2 PKD2 CACNA1I CACNA1H	8.68e-05	152	137	7	GO:0022843
GeneOntologyMolecularFunction	gated channel activity	KCNH7 ABCC9 TPCN1 KCNH6 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H	1.05e-04	334	137	10	GO:0022836
GeneOntologyMolecularFunction	low voltage-gated calcium channel activity	CACNA1I CACNA1H	1.40e-04	3	137	2	GO:0008332
GeneOntologyMolecularFunction	pancreatic polypeptide receptor activity	NPY4R2 NPY4R	2.78e-04	4	137	2	GO:0001602
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	KCNH7 ABCC9 TPCN1 KCNH6 KCNH2 ANO6 PKD2	3.77e-04	193	137	7	GO:0015276
GeneOntologyMolecularFunction	AMP binding	PRPS2 ACSS1 PRPS1	3.84e-04	21	137	3	GO:0016208
GeneOntologyMolecularFunction	ligand-gated channel activity	KCNH7 ABCC9 TPCN1 KCNH6 KCNH2 ANO6 PKD2	4.27e-04	197	137	7	GO:0022834
GeneOntologyMolecularFunction	ribose phosphate diphosphokinase activity	PRPS2 PRPS1	4.61e-04	5	137	2	GO:0004749
GeneOntologyMolecularFunction	diphosphotransferase activity	PRPS2 PRPS1	6.88e-04	6	137	2	GO:0016778
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNH7 ABCC9 KCNH6 KCNH2 PKD2	6.91e-04	102	137	5	GO:0005249
GeneOntologyMolecularFunction	GTPase activator activity	ARHGAP32 SGSM1 ARHGAP26 ARHGEF12 ARHGAP6 ASAP2 NF1 IQGAP3	6.95e-04	279	137	8	GO:0005096
GeneOntologyMolecularFunction	dynein light intermediate chain binding	RILPL2 DNAH14 DNAH11	9.13e-04	28	137	3	GO:0051959
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNH7 ABCC9 KCNH6 SLC9C1 KCNH2 PKD2	1.04e-03	167	137	6	GO:0015079
GeneOntologyMolecularFunction	small GTPase binding	KNTC1 SGSM1 RILPL2 MYCBP2 EXOC8 CYFIP1 ARHGEF2 IQGAP3	1.70e-03	321	137	8	GO:0031267
GeneOntologyMolecularFunction	potassium channel activity	KCNH7 ABCC9 KCNH6 KCNH2 PKD2	1.90e-03	128	137	5	GO:0005267
GeneOntologyMolecularFunction	store-operated calcium channel activity	TRPC1 TRPC6	2.95e-03	12	137	2	GO:0015279
GeneOntologyMolecularFunction	ammonium channel activity	RHCE RHD	2.95e-03	12	137	2	GO:0008519
GeneOntologyMolecularFunction	GTPase binding	KNTC1 SGSM1 RILPL2 MYCBP2 EXOC8 CYFIP1 ARHGEF2 IQGAP3	3.45e-03	360	137	8	GO:0051020
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	PKD2 CACNA1I CACNA1H	3.87e-03	46	137	3	GO:0005245
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1I CACNA1H	4.03e-03	14	137	2	GO:0008331
GeneOntologyMolecularFunction	inositol 1,4,5 trisphosphate binding	TRPC1 TRPC6	4.03e-03	14	137	2	GO:0070679
GeneOntologyMolecularFunction	RNA 7-methylguanosine cap binding	NCBP1 CYFIP1	4.03e-03	14	137	2	GO:0000340
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase regulatory subunit binding	FAM83B FAM83A	4.03e-03	14	137	2	GO:0036312
GeneOntologyMolecularFunction	ADP binding	PRPS2 ATP5F1B PRPS1	4.36e-03	48	137	3	GO:0043531
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP8B3 ATP10D ANO6	5.17e-03	51	137	3	GO:0140303
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	ARHGEF28 MYCBP2 ARHGEF12 EGF ARHGEF2 DOCK6	5.25e-03	231	137	6	GO:0005085
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9B1 SLC9C1	5.27e-03	16	137	2	GO:0015385
GeneOntologyMolecularFunction	GDP binding	PRPS2 NGB SRP54 PRPS1	5.55e-03	103	137	4	GO:0019003
GeneOntologyMolecularFunction	neuropeptide receptor activity	QRFPR NPY4R2 NPY4R	5.76e-03	53	137	3	GO:0008188
GeneOntologyMolecularFunction	oxidoreductase activity, acting on other nitrogenous compounds as donors	NGB ALDH2	5.94e-03	17	137	2	GO:0016661
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	ABCC9 ADAMTS8 SLC1A4 ANO6 SLC4A4	6.55e-03	171	137	5	GO:0015103
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	TPCN1 PKD2	6.65e-03	18	137	2	GO:0015278
GeneOntologyMolecularFunction	adenylate cyclase activity	ADCY8 ADCY9	6.65e-03	18	137	2	GO:0004016
GeneOntologyMolecularFunction	cyclase regulator activity	RCVRN ADGRV1	6.65e-03	18	137	2	GO:0010851
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH14 DNAH11	6.65e-03	18	137	2	GO:0008569
GeneOntologyBiologicalProcess	monoatomic cation transport	KCNH7 TRPC1 TRPC6 RCVRN ABCC9 PKDREJ ATP10D TPCN1 GRAMD2A KCNH6 SLC9B1 SLC9C1 PPP3CB EGF KCNH2 ANO6 SCN2A MCUR1 PKD2 CACNA1I CACNA1H SLC4A4 CXCL12 ATP5F1B	4.58e-07	1157	135	24	GO:0006812
GeneOntologyBiologicalProcess	metal ion transport	KCNH7 TRPC1 TRPC6 RCVRN ABCC9 PKDREJ TPCN1 GRAMD2A KCNH6 SLC9B1 SLC9C1 PPP3CB EGF KCNH2 ANO6 SCN2A MCUR1 PKD2 CACNA1I CACNA1H SLC4A4 CXCL12	5.55e-07	1000	135	22	GO:0030001
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ RHCE RHD TPCN1 KCNH6 SLC9B1 SLC9C1 PPP3CB KCNH2 ANO6 SCN2A MCUR1 PKD2 CACNA1I CACNA1H SLC4A4 ATP5F1B	5.94e-07	922	135	21	GO:0098662
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ SLC1A4 RHCE RHD TPCN1 KCNH6 SLC9B1 SLC9C1 PPP3CB KCNH2 ANO6 SCN2A MCUR1 PKD2 CACNA1I CACNA1H SLC4A4 ATP5F1B	7.36e-07	1017	135	22	GO:0098660
GeneOntologyBiologicalProcess	monoatomic ion transport	KCNH7 TRPC1 TRPC6 RCVRN ABCC9 PKDREJ SLC1A4 ATP10D TPCN1 GRAMD2A KCNH6 SLC9B1 SLC9C1 PPP3CB EGF KCNH2 ANO6 SCN2A MCUR1 PKD2 CACNA1I CACNA1H SLC4A4 CXCL12 ATP5F1B	2.78e-06	1374	135	25	GO:0006811
GeneOntologyBiologicalProcess	calcium ion import	PPP3CB EGF MCUR1 PKD2 CACNA1I CACNA1H CXCL12	3.71e-06	98	135	7	GO:0070509
GeneOntologyBiologicalProcess	calcium ion transport	TRPC1 TRPC6 RCVRN PKDREJ TPCN1 GRAMD2A PPP3CB EGF ANO6 MCUR1 PKD2 CACNA1I CACNA1H CXCL12	6.47e-06	509	135	14	GO:0006816
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	TPCN1 SLC9B1 SLC9C1 ANO6 SCN2A PKD2 CACNA1I CACNA1H SLC4A4	9.47e-06	208	135	9	GO:0035725
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ SLC1A4 ATP10D TPCN1 KCNH6 SLC9B1 SLC9C1 PPP3CB KCNH2 ANO6 SCN2A MCUR1 PKD2 CACNA1I CACNA1H SLC4A4 ATP5F1B	1.16e-05	1115	135	21	GO:0034220
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	KCNH7 TRPC1 TRPC6 ABCC9 PKDREJ TPCN1 KCNH6 SLC9B1 SLC9C1 PPP3CB KCNH2 ANO6 SCN2A MCUR1 PKD2 CACNA1I CACNA1H SLC4A4 ATP5F1B	1.24e-05	942	135	19	GO:0098655
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	TRPC1 TRPC6 TRIM24 ADCY8 RHCE RHD CKB SLC9B1 SLC9C1 KCNH2 MCUR1 PKD2 SLC4A4 CXCL12 ATP5F1B	7.28e-05	717	135	15	GO:0050801
GeneOntologyBiologicalProcess	sodium ion transport	TPCN1 SLC9B1 SLC9C1 ANO6 SCN2A PKD2 CACNA1I CACNA1H SLC4A4	8.45e-05	275	135	9	GO:0006814
GeneOntologyBiologicalProcess	membrane depolarization during action potential	KCNH2 SCN2A CACNA1I CACNA1H	8.79e-05	36	135	4	GO:0086010
GeneOntologyBiologicalProcess	Rho protein signal transduction	CUL3 ARHGAP32 ARHGEF28 ARHGEF12 ARHGAP6 CELSR1 ARHGEF2	1.04e-04	164	135	7	GO:0007266
GeneOntologyBiologicalProcess	export from cell	AHI1 TRARG1 TRPC1 COPG2 NIBAN2 ADCY8 EXOC8 NF1 PPP3CB CADPS KCNH2 ANO6 CACNA1I C1QTNF1 CACNA1H SLC4A4 CADPS2 STX11 CXCL12	1.86e-04	1153	135	19	GO:0140352
GeneOntologyBiologicalProcess	calcium-ion regulated exocytosis	PPP3CB CADPS CACNA1I CACNA1H CADPS2	2.03e-04	82	135	5	GO:0017156
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	TRPC1 TRPC6 TRIM24 ADCY8 RHCE RHD SLC9B1 SLC9C1 KCNH2 MCUR1 PKD2 SLC4A4 CXCL12 ATP5F1B	2.20e-04	705	135	14	GO:0055080
GeneOntologyBiologicalProcess	small GTPase-mediated signal transduction	CUL3 ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 ARHGAP6 CELSR1 CYFIP1 NF1 ARHGEF2 DOCK6 IQGAP3	2.21e-04	538	135	12	GO:0007264
GeneOntologyBiologicalProcess	ubiquitin-dependent protein catabolic process via the N-end rule pathway	UBR2 UBR4	2.53e-04	4	135	2	GO:0071596
GeneOntologyBiologicalProcess	calcium ion transmembrane transport	TRPC1 TRPC6 PKDREJ TPCN1 PPP3CB ANO6 MCUR1 PKD2 CACNA1I CACNA1H	2.62e-04	392	135	10	GO:0070588
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR6B1 OR6K2 TRPC1 FPR3 ARHGEF12 ADGRV1 ADCY8 ADCY9 RLN1 ADGRG7 QRFPR NPY4R2 CELSR1 GNA14 NPY4R OR10K1 TENM1 ADGRE5 ADGRF4 ADGRE1 CXCL12	2.86e-04	1395	135	21	GO:0007186
GeneOntologyBiologicalProcess	positive regulation of calcium ion-dependent exocytosis	CADPS CACNA1I CACNA1H	2.88e-04	20	135	3	GO:0045956
GeneOntologyBiologicalProcess	actin filament-based process	CUL3 ARHGAP26 PPM1E ABCC9 ARHGAP6 CELSR1 CYFIP1 NF1 KCNH2 MICAL2 SCN2A TENM1 CACNA1H ARHGEF2 IQGAP3 CXCL12	3.13e-04	912	135	16	GO:0030029
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	ABCC9 SLC9C1 PPP3CB KCNH2 CACNA1I CACNA1H	3.47e-04	142	135	6	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	ABCC9 SLC9C1 PPP3CB KCNH2 CACNA1I CACNA1H	3.47e-04	142	135	6	GO:0098659
GeneOntologyBiologicalProcess	action potential	ABCC9 KCNH6 GNA14 KCNH2 SCN2A CACNA1I CACNA1H	3.64e-04	201	135	7	GO:0001508
GeneOntologyBiologicalProcess	regulation of metal ion transport	TRPC1 TRPC6 RCVRN ABCC9 GRAMD2A PPP3CB EGF KCNH2 ANO6 PKD2 CXCL12	4.06e-04	493	135	11	GO:0010959
GeneOntologyBiologicalProcess	protein retention in Golgi apparatus	VPS13C VPS13D	4.20e-04	5	135	2	GO:0045053
GeneOntologyCellularComponent	monoatomic ion channel complex	KCNH7 TRPC1 TRPC6 ABCC9 TPCN1 KCNH6 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H ATP5F1B	1.27e-06	378	137	13	GO:0034702
GeneOntologyCellularComponent	transporter complex	ATP8B3 KCNH7 TRPC1 TRPC6 ABCC9 ATP10D TPCN1 KCNH6 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H ATP5F1B	3.36e-06	550	137	15	GO:1990351
GeneOntologyCellularComponent	cation channel complex	TRPC1 TRPC6 ABCC9 KCNH2 SCN2A PKD2 CACNA1I CACNA1H ATP5F1B	2.53e-05	235	137	9	GO:0034703
GeneOntologyCellularComponent	transmembrane transporter complex	KCNH7 TRPC1 TRPC6 ABCC9 TPCN1 KCNH6 KCNH2 ANO6 SCN2A PKD2 CACNA1I CACNA1H ATP5F1B	4.11e-05	523	137	13	GO:1902495
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN2A CACNA1I CACNA1H	1.75e-04	17	137	3	GO:0001518
GeneOntologyCellularComponent	cilium	CUL3 AHI1 RILPL2 RCVRN ADGRV1 DNAH14 FSIP2 QRFPR SLC9B1 ODF2L SLC9C1 PTPRK PKD2 CFAP206 USP48 DNAH11	2.69e-04	898	137	16	GO:0005929
GeneOntologyCellularComponent	ribose phosphate diphosphokinase complex	PRPS2 PRPS1	4.21e-04	5	137	2	GO:0002189
GeneOntologyCellularComponent	sodium channel complex	SCN2A CACNA1I CACNA1H	8.88e-04	29	137	3	GO:0034706
Domain	GPS	ADGRV1 PKDREJ ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	7.19e-09	37	134	7	IPR000203
Domain	Ion_trans_dom	KCNH7 TRPC1 TRPC6 TPCN1 KCNH6 SLC9C1 KCNH2 SCN2A CACNA1I CACNA1H	9.31e-09	114	134	10	IPR005821
Domain	Ion_trans	KCNH7 TRPC1 TRPC6 TPCN1 KCNH6 SLC9C1 KCNH2 SCN2A CACNA1I CACNA1H	9.31e-09	114	134	10	PF00520
Domain	GPS	ADGRV1 PKDREJ ADGRG7 CELSR1 ADGRE5 ADGRE1	1.39e-07	34	134	6	SM00303
Domain	GPS	ADGRV1 ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	1.67e-07	35	134	6	PF01825
Domain	GPS	ADGRV1 ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	1.99e-07	36	134	6	PS50221
Domain	K_chnl_volt-dep_ERG	KCNH7 KCNH6 KCNH2	3.61e-07	3	134	3	IPR003967
Domain	7tm_2	ADGRV1 ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	1.49e-06	50	134	6	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRV1 ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	1.49e-06	50	134	6	PS00650
Domain	GPCR_2_secretin-like	ADGRV1 ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	4.44e-06	60	134	6	IPR000832
Domain	GPCR_2-like	ADGRV1 ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	4.44e-06	60	134	6	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRV1 ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	4.90e-06	61	134	6	PS50261
Domain	NPY_rcpt	QRFPR NPY4R2 NPY4R	2.94e-05	9	134	3	IPR000611
Domain	PAS_9	KCNH7 KCNH6 KCNH2	4.18e-05	10	134	3	PF13426
Domain	EGF	CNTNAP3B CNTNAP3 MUC13 ADAM32 CELSR1 EGF TENM1 ADGRE5 ADGRE1	5.06e-05	235	134	9	SM00181
Domain	EGF_3	CNTNAP3B CNTNAP3 MUC13 ADAM32 CELSR1 EGF TENM1 ADGRE5 ADGRE1	5.06e-05	235	134	9	PS50026
Domain	CAPS	CADPS CADPS2	5.11e-05	2	134	2	IPR033227
Domain	NPY4_rcpt	NPY4R2 NPY4R	5.11e-05	2	134	2	IPR001933
Domain	Channel_four-helix_dom	TPCN1 SCN2A PKD2 CACNA1I CACNA1H	5.47e-05	57	134	5	IPR027359
Domain	-	TPCN1 SCN2A PKD2 CACNA1I CACNA1H	5.47e-05	57	134	5	1.20.120.350
Domain	CNMP_BINDING_1	KCNH7 KCNH6 SLC9C1 KCNH2	7.79e-05	32	134	4	PS00888
Domain	CNMP_BINDING_2	KCNH7 KCNH6 SLC9C1 KCNH2	7.79e-05	32	134	4	PS00889
Domain	EGF-like_dom	CNTNAP3B CNTNAP3 MUC13 ADAM32 CELSR1 EGF TENM1 ADGRE5 ADGRE1	7.90e-05	249	134	9	IPR000742
Domain	cNMP	KCNH7 KCNH6 SLC9C1 KCNH2	9.94e-05	34	134	4	SM00100
Domain	cNMP_binding	KCNH7 KCNH6 SLC9C1 KCNH2	9.94e-05	34	134	4	PF00027
Domain	cNMP-bd_dom	KCNH7 KCNH6 SLC9C1 KCNH2	1.12e-04	35	134	4	IPR000595
Domain	CNMP_BINDING_3	KCNH7 KCNH6 SLC9C1 KCNH2	1.12e-04	35	134	4	PS50042
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH7 KCNH6 KCNH2	1.24e-04	14	134	3	IPR003938
Domain	PRPP_SYNTHASE	PRPS2 PRPS1	1.53e-04	3	134	2	PS00114
Domain	VDCC_T_a1	CACNA1I CACNA1H	1.53e-04	3	134	2	IPR005445
Domain	VPS13	VPS13C VPS13D	1.53e-04	3	134	2	IPR026847
Domain	VPS13_mid_rpt	VPS13C VPS13D	1.53e-04	3	134	2	PF16910
Domain	VPS13	VPS13C VPS13D	1.53e-04	3	134	2	PF16908
Domain	PRib_PP_synth_CS	PRPS2 PRPS1	1.53e-04	3	134	2	IPR000842
Domain	VPS13_N2	VPS13C VPS13D	1.53e-04	3	134	2	IPR031646
Domain	VPS13_mid_rpt	VPS13C VPS13D	1.53e-04	3	134	2	IPR031642
Domain	cNMP-bd-like	KCNH7 KCNH6 SLC9C1 KCNH2	1.55e-04	38	134	4	IPR018490
Domain	PH	ARHGEF28 ARHGAP26 ARHGEF12 NIBAN2 EXOC8 ASAP2 CADPS ARHGEF2 CADPS2	1.82e-04	278	134	9	SM00233
Domain	PH_DOMAIN	ARHGEF28 ARHGAP26 ARHGEF12 NIBAN2 EXOC8 ASAP2 CADPS ARHGEF2 CADPS2	1.87e-04	279	134	9	PS50003
Domain	PH_domain	ARHGEF28 ARHGAP26 ARHGEF12 NIBAN2 EXOC8 ASAP2 CADPS ARHGEF2 CADPS2	1.92e-04	280	134	9	IPR001849
Domain	PH_dom-like	ARHGEF28 NBEAL1 ARHGAP26 ARHGEF12 NBEA NIBAN2 EXOC8 ASAP2 CADPS ARHGEF2 CADPS2	2.54e-04	426	134	11	IPR011993
Domain	SHR-BD	VPS13C VPS13D	3.04e-04	4	134	2	IPR009543
Domain	VPS13_C	VPS13C VPS13D	3.04e-04	4	134	2	PF16909
Domain	VPS13_C	VPS13C VPS13D	3.04e-04	4	134	2	IPR031645
Domain	SHR-BD	VPS13C VPS13D	3.04e-04	4	134	2	PF06650
Domain	-	KCNH7 KCNH6 SLC9C1 KCNH2	3.86e-04	48	134	4	2.60.120.10
Domain	Rho_GTPase_activation_prot	ARHGAP32 ARHGAP26 ARHGAP6 NF1 IQGAP3	4.29e-04	88	134	5	IPR008936
Domain	RmlC-like_jellyroll	KCNH7 KCNH6 SLC9C1 KCNH2	4.88e-04	51	134	4	IPR014710
Domain	Pribosyltran_N	PRPS2 PRPS1	5.04e-04	5	134	2	PF13793
Domain	Ammonium_transpt	RHCE RHD	5.04e-04	5	134	2	IPR001905
Domain	Pribosyl_synth	PRPS2 PRPS1	5.04e-04	5	134	2	PF14572
Domain	Rib-P_diPkinase	PRPS2 PRPS1	5.04e-04	5	134	2	IPR005946
Domain	Pribosyltran_N	PRPS2 PRPS1	5.04e-04	5	134	2	IPR029099
Domain	PKD_2	PKDREJ PKD2	5.04e-04	5	134	2	IPR003915
Domain	DUF4704	NBEAL1 NBEA	5.04e-04	5	134	2	IPR031570
Domain	DUF4704	NBEAL1 NBEA	5.04e-04	5	134	2	PF15787
Domain	Ammonium_transp	RHCE RHD	5.04e-04	5	134	2	PF00909
Domain	NH4_transpt_AmtB-like_dom	RHCE RHD	5.04e-04	5	134	2	IPR024041
Domain	DUF1041	CADPS CADPS2	5.04e-04	5	134	2	SM01145
Domain	RhesusRHD	RHCE RHD	5.04e-04	5	134	2	IPR002229
Domain	EGF_1	CNTNAP3B CNTNAP3 MUC13 ADAM32 CELSR1 EGF TENM1 ADGRE1	5.13e-04	255	134	8	PS00022
Domain	-	NBEAL1 CNTNAP3 NBEA ADGRV1 CELSR1	6.10e-04	95	134	5	2.60.120.200
Domain	PAS-assoc_C	KCNH7 KCNH6 KCNH2	6.55e-04	24	134	3	IPR000700
Domain	EGF_2	CNTNAP3B CNTNAP3 MUC13 ADAM32 CELSR1 EGF TENM1 ADGRE1	6.61e-04	265	134	8	PS01186
Domain	TRP_2	TRPC1 TRPC6	7.52e-04	6	134	2	PF08344
Domain	PH_BEACH	NBEAL1 NBEA	7.52e-04	6	134	2	PF14844
Domain	TRP_dom	TRPC1 TRPC6	7.52e-04	6	134	2	IPR013555
Domain	PAC	KCNH7 KCNH6 KCNH2	8.32e-04	26	134	3	IPR001610
Domain	PAC	KCNH7 KCNH6 KCNH2	8.32e-04	26	134	3	PS50113
Domain	PAC	KCNH7 KCNH6 KCNH2	8.32e-04	26	134	3	SM00086
Domain	ConA-like_dom	CNTNAP3B NBEAL1 CNTNAP3 NBEA ADGRV1 CELSR1 PTPRK	1.03e-03	219	134	7	IPR013320
Domain	Munc13_1	CADPS CADPS2	1.05e-03	7	134	2	IPR014770
Domain	MHD1	CADPS CADPS2	1.05e-03	7	134	2	PS51258
Domain	TRPC_channel	TRPC1 TRPC6	1.05e-03	7	134	2	IPR002153
Domain	ZnF_UBR1	UBR2 UBR4	1.05e-03	7	134	2	SM00396
Domain	DUF1041	CADPS CADPS2	1.05e-03	7	134	2	PF06292
Domain	-	RHCE RHD	1.05e-03	7	134	2	1.10.3430.10
Domain	CAPS_dom	CADPS CADPS2	1.05e-03	7	134	2	IPR010439
Domain	Ammonium/urea_transptr	RHCE RHD	1.05e-03	7	134	2	IPR029020
Domain	ZF_UBR	UBR2 UBR4	1.05e-03	7	134	2	PS51157
Domain	zf-UBR	UBR2 UBR4	1.05e-03	7	134	2	PF02207
Domain	Znf_UBR	UBR2 UBR4	1.05e-03	7	134	2	IPR003126
Domain	Chorein_N	VPS13C VPS13D	1.39e-03	8	134	2	PF12624
Domain	DUF1669	FAM83B FAM83A	1.39e-03	8	134	2	PF07894
Domain	PH-BEACH_dom	NBEAL1 NBEA	1.39e-03	8	134	2	IPR023362
Domain	DUF1669	FAM83B FAM83A	1.39e-03	8	134	2	IPR012461
Domain	VPS13_N	VPS13C VPS13D	1.39e-03	8	134	2	IPR026854
Domain	-	NBEAL1 NBEA	1.39e-03	8	134	2	2.30.29.40
Domain	PH_BEACH	NBEAL1 NBEA	1.39e-03	8	134	2	PS51783
Domain	BEACH	NBEAL1 NBEA	1.78e-03	9	134	2	PS50197
Domain	Beach	NBEAL1 NBEA	1.78e-03	9	134	2	PF02138
Domain	-	NBEAL1 NBEA	1.78e-03	9	134	2	1.10.1540.10
Domain	Beach	NBEAL1 NBEA	1.78e-03	9	134	2	SM01026
Domain	BEACH_dom	NBEAL1 NBEA	1.78e-03	9	134	2	IPR000409
Domain	PAS	KCNH7 KCNH6 KCNH2	1.84e-03	34	134	3	PS50112
Domain	PAS	KCNH7 KCNH6 KCNH2	1.84e-03	34	134	3	IPR000014
Domain	-	ARHGEF28 ARHGAP26 ARHGEF12 NIBAN2 EXOC8 ASAP2 CADPS ARHGEF2 CADPS2	2.06e-03	391	134	9	2.30.29.30
Domain	Hydrolase_3	ATP8B3 ATP10D	2.21e-03	10	134	2	PF08282
Domain	VDCCAlpha1	CACNA1I CACNA1H	2.21e-03	10	134	2	IPR002077
Domain	LAM_G_DOMAIN	CNTNAP3B CNTNAP3 CELSR1	2.54e-03	38	134	3	PS50025
Pathway	REACTOME_RHOB_GTPASE_CYCLE	ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 ARHGEF2 IQGAP3	9.69e-06	69	101	6	MM15596
Pathway	REACTOME_RHOB_GTPASE_CYCLE	ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 ARHGEF2 IQGAP3	1.05e-05	70	101	6	M41806
Pathway	REACTOME_RHO_GTPASE_CYCLE	CUL3 ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 MUC13 FAM83B CKB ARHGAP6 CYFIP1 ARHGEF2 DOCK6 IQGAP3	1.46e-05	439	101	13	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	CUL3 ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 MUC13 FAM83B CKB ARHGAP6 CYFIP1 ARHGEF2 DOCK6 IQGAP3	1.90e-05	450	101	13	M27078
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 TRPC1 TRPC6 ATP10D TPCN1 SLC9B1 SLC9C1 ANO6	5.00e-05	183	101	8	M997
Pathway	REACTOME_RHOA_GTPASE_CYCLE	ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 ARHGAP6 ARHGEF2 IQGAP3	7.09e-05	142	101	7	MM15576
Pathway	REACTOME_RHOA_GTPASE_CYCLE	ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 ARHGAP6 ARHGEF2 IQGAP3	9.60e-05	149	101	7	M41805
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPC1 TRPC6 TPCN1 SLC9B1 SLC9C1 ANO6	1.11e-04	106	101	6	M27200
Pathway	REACTOME_RHOC_GTPASE_CYCLE	ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 IQGAP3	1.43e-04	70	101	5	MM15597
Pathway	REACTOME_RHOC_GTPASE_CYCLE	ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 IQGAP3	1.86e-04	74	101	5	M41807
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	CUL3 KNTC1 ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 MUC13 FAM83B CKB ARHGAP6 CYFIP1 ARHGEF2 DOCK6 IQGAP3	2.10e-04	649	101	14	MM15690
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP8B3 TRPC1 TRPC6 ATP10D TPCN1 SLC9B1 ANO6	2.69e-04	176	101	7	MM15718
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	TRPC1 ADCY8 ADCY9 PPP3CB GNA14 CACNA1I CACNA1H	2.88e-04	178	101	7	M2890
Pathway	PID_RHOA_REG_PATHWAY	ARHGEF28 ARHGEF12 ARHGAP6 ARHGEF2	3.22e-04	46	101	4	M68
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	NBEA ADCY8 ADCY9	3.72e-04	20	101	3	M759
Pathway	REACTOME_SIGNALING_BY_EGFR	FAM83B EGF PTPRK FAM83A	4.11e-04	49	101	4	MM14695
Pathway	REACTOME_OPIOID_SIGNALLING	NBEA ADCY8 ADCY9 PPP3CB GNA14	4.64e-04	90	101	5	M6467
Pathway	REACTOME_SIGNALING_BY_GPCR	FPR3 TRPC6 ARHGEF12 NBEA ADCY8 ADCY9 QRFPR PPP3CB GNA14 NPY4R ADGRE5 ARHGEF2 ADGRE1 CXCL12	4.66e-04	702	101	14	M746
Pathway	REACTOME_SIGNALING_BY_EGFR	FAM83B EGF PTPRK FAM83A	5.55e-04	53	101	4	M27039
Pathway	REACTOME_G_PROTEIN_MEDIATED_EVENTS	NBEA ADCY8 ADCY9 GNA14	5.96e-04	54	101	4	M26911
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	CUL3 KNTC1 ARHGAP32 ARHGEF28 ARHGAP26 ARHGEF12 MUC13 FAM83B CKB ARHGAP6 CYFIP1 ARHGEF2 DOCK6 IQGAP3	5.99e-04	720	101	14	M41838
Pathway	REACTOME_MUSCLE_CONTRACTION	TRPC1 ABCC9 KCNH2 SCN2A CACNA1I CACNA1H ALDH2	6.35e-04	203	101	7	M5485
Pathway	REACTOME_SIGNALING_BY_GPCR	FPR3 TRPC6 ARHGEF12 ADCY8 ADCY9 RLN1 QRFPR GNA14 NPY4R ADGRE5 ARHGEF2 ADGRE1 CXCL12	6.93e-04	646	101	13	MM14962
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPC1 TRPC6 TPCN1 SLC9B1 ANO6	7.18e-04	99	101	5	MM14910
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ATP8B3 NGB TRPC1 TRPC6 ABCC9 SLC1A4 ADCY8 ADCY9 ATP10D TPCN1 SLC9B1 SLC9C1 ANO6 SLC4A4	7.43e-04	736	101	14	M27287
Pathway	PID_ENDOTHELIN_PATHWAY	TRPC6 ADCY8 ADCY9 GNA14	1.07e-03	63	101	4	M8
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRV1 ADGRG7 CELSR1 ADGRE5 ADGRF4 ADGRE1	3.40e-09	33	137	6	25713288
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CUL3 DDX19B TUT4 NPEPPS VPS13C ARHGEF12 NIBAN2 ADGRV1 CFI SUCLA2 CKB VPS13D EGF ANO6 PKD2 SLC35F6 ALDH2 SLC4A4 NIPBL ATP5F1B	3.51e-09	1016	137	20	19056867
Pubmed	HERG K(+) currents in human prolactin-secreting adenoma cells.	KCNH7 KCNH6 KCNH2	5.98e-08	3	137	3	12634931
Pubmed	Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.	KCNH7 KCNH6 KCNH2	5.98e-08	3	137	3	14643686
Pubmed	Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.	KCNH7 KCNH6 KCNH2	5.98e-08	3	137	3	35818223
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CUL3 ARHGAP32 NPEPPS ARHGAP26 ARHGEF12 NBEA SUCLA2 SLC1A4 WDR47 CKB CYFIP1 NF1 CADPS MICAL2 SCN2A ALDH2 ARHGEF2 SLC4A4 ATP5F1B DNAH11 PRPS1	2.08e-07	1431	137	21	37142655
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	PRPS2 CNTNAP3B NPEPPS TM9SF3 CNTNAP3 COPG2 MUC13 ADCY9 NF1 ANO6 SLC35F6 ADGRE5 ALDH2 ARHGEF2 SLC4A4 VAMP4 DOCK6 ATP5F1B	2.09e-07	1061	137	18	33845483
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DDX19B DDX19A SRP54 COPG2 NCBP1 NIBAN2 TUBGCP4 GMPS NF1 GNA14 ARHGEF2 USP48 NIPBL	5.69e-07	582	137	13	20467437
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBR2 TUT4 SGSM1 MYCBP2 NPEPPS VPS13C SRP54 ADGRV1 SUCLA2 SFMBT2 DNAH14 HPS3 GMPS ARHGAP6 ODF2L ASAP2 MICAL2 PKD2 CACNA1H DOCK6	1.65e-06	1489	137	20	28611215
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	DDX19B DDX19A TUT4 MYCBP2 VPS13C ACSS1 UBR4 TM9SF3 SRP54 SUCLA2 ADCY9 FAM83B CKB VPS13D CEPT1 MCUR1 ALDH2 ARHGEF2 EIF2AK3 ATP5F1B	1.77e-06	1496	137	20	32877691
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	PRPS2 CUL3 DDX19B DDX19A MYCBP2 NPEPPS UBR4 TM9SF3 NCBP1 SUCLA2 GMPS URB1 CEPT1 CYFIP1 PPP3CB IQGAP3 ATP5F1B PRPS1	2.37e-06	1257	137	18	37317656
Pubmed	Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain.	CADPS CADPS2 VAMP4	3.30e-06	8	137	3	16506193
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRV1 ADGRG7 ADGRF4 ADGRE1	5.07e-06	29	137	4	15203201
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	UBR2 MYCBP2 TM9SF3 CNTNAP3 TPCN1 NXPE3 CELSR1 NF1 PTPRK MICAL2 ANO6 PKD2 ADGRE5 USP48 EIF2AK3 ATP5F1B CHST3	5.38e-06	1201	137	17	35696571
Pubmed	Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.	KCNH7 KCNH6 KCNH2	7.03e-06	10	137	3	26503718
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPC1 TRPC6 PKDREJ PKD2	8.63e-06	33	137	4	19834762
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	DDX19B ARHGAP32 ARHGAP26 UBR4 TM9SF3 NBEA TRIM24 CYFIP1 NF1 ARHGEF2 NIPBL DNAH11	9.07e-06	638	137	12	31182584
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KNTC1 DDX19A NPEPPS VPS13C TRPC1 UBR4 TM9SF3 NCBP1 SUCLA2 CKB URB1 CYFIP1 NF1 ALDH2 NIPBL IQGAP3 ATP5F1B PRPS1	1.32e-05	1425	137	18	30948266
Pubmed	Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region.	RHCE RHD	1.54e-05	2	137	2	8188244
Pubmed	CAPS1 and CAPS2 regulate stability and recruitment of insulin granules in mouse pancreatic beta cells.	CADPS CADPS2	1.54e-05	2	137	2	18177725
Pubmed	A T-type calcium channel required for normal function of a mammalian mechanoreceptor.	CACNA1I CACNA1H	1.54e-05	2	137	2	12808460
Pubmed	DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.	RHCE RHD	1.54e-05	2	137	2	17900276
Pubmed	RHD and RHCE molecular analysis in weak D blood donors and in patients with Rh antibodies against their own corresponding Rh antigen.	RHCE RHD	1.54e-05	2	137	2	32697929
Pubmed	Transient receptor potential channels TRPC1/TRPC6 regulate lamina cribrosa cell extracellular matrix gene transcription and proliferation.	TRPC1 TRPC6	1.54e-05	2	137	2	32088241
Pubmed	Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice.	CACNA1I CACNA1H	1.54e-05	2	137	2	25071191
Pubmed	Classical transient receptor potential 1 and 6 contribute to hypoxic pulmonary hypertension through differential regulation of pulmonary vascular functions.	TRPC1 TRPC6	1.54e-05	2	137	2	24144647
Pubmed	Cooperative roles of SDF-1α and EGF gradients on tumor cell migration revealed by a robust 3D microfluidic model.	EGF CXCL12	1.54e-05	2	137	2	23869217
Pubmed	Review: the molecular basis of the Rh blood group phenotypes.	RHCE RHD	1.54e-05	2	137	2	15373666
Pubmed	Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations.	RHCE RHD	1.54e-05	2	137	2	26579938
Pubmed	TRPC channels blockade abolishes endotoxemic cardiac dysfunction by hampering intracellular inflammation and Ca2+ leakage.	TRPC1 TRPC6	1.54e-05	2	137	2	36460692
Pubmed	Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion.	RHCE RHD	1.54e-05	2	137	2	34968422
Pubmed	Regarding the size of Rh proteins.	RHCE RHD	1.54e-05	2	137	2	1898705
Pubmed	Whole Exome Sequencing of Hemiplegic Migraine Patients Shows an Increased Burden of Missense Variants in CACNA1H and CACNA1I Genes.	CACNA1I CACNA1H	1.54e-05	2	137	2	36786913
Pubmed	The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement.	TRPC1 PKD2	1.54e-05	2	137	2	19850920
Pubmed	PCR screening for common weak D types shows different distributions in three Central European populations.	RHCE RHD	1.54e-05	2	137	2	11161244
Pubmed	RH diversity in Mali: characterization of a new haplotype RHDDIVa/RHCEceTI(D2).	RHCE RHD	1.54e-05	2	137	2	25857637
Pubmed	The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCEce818T alleles that are often in cis to RHDDOL.	RHCE RHD	1.54e-05	2	137	2	22738288
Pubmed	Multiple Rh messenger RNA isoforms are produced by alternative splicing.	RHCE RHD	1.54e-05	2	137	2	1379850
Pubmed	Nuclear magnetic resonance structure of the cytoplasmic tail of heparin binding EGF-like growth factor (proHB-EGF-CT) complexed with the ubiquitin homology domain of Bcl-2-associated athanogene 1 from Mus musculus (mBAG-1-UBH).	BAG1 EGF	1.54e-05	2	137	2	24628338
Pubmed	Characterization of the mouse Rh blood group gene.	RHCE RHD	1.54e-05	2	137	2	10329015
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	1.54e-05	2	137	2	26807827
Pubmed	The eag family of K+ channels in Drosophila and mammals.	KCNH7 KCNH6	1.54e-05	2	137	2	10414305
Pubmed	CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins.	CADPS CADPS2	1.54e-05	2	137	2	18022372
Pubmed	RHCEceMO is frequently in cis to RHDDAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance.	RHCE RHD	1.54e-05	2	137	2	23772606
Pubmed	Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.	RHCE RHD	1.54e-05	2	137	2	3135863
Pubmed	CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons.	CADPS CADPS2	1.54e-05	2	137	2	28883501
Pubmed	Sequences and evolution of mammalian RH gene transcripts and proteins.	RHCE RHD	1.54e-05	2	137	2	9811965
Pubmed	Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety.	RHCE RHD	1.54e-05	2	137	2	12393640
Pubmed	Molecular genetic basis of the human Rhesus blood group system.	RHCE RHD	1.54e-05	2	137	2	8220426
Pubmed	Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system.	RHCE RHD	1.54e-05	2	137	2	7916743
Pubmed	RHDDOL1 and RHDDOL2 encode a partial D antigen and are in cis with the rare RHCE*ceBI allele in people of African descent.	RHCE RHD	1.54e-05	2	137	2	22690701
Pubmed	No Distinction of Orthology/Paralogy between Human and Chimpanzee Rh Blood Group Genes.	RHCE RHD	1.54e-05	2	137	2	26872772
Pubmed	RHCEceTI encodes partial c and partial e and is often in cis to RHDDIVa.	RHCE RHD	1.54e-05	2	137	2	22804620
Pubmed	Revisiting TRPC1 and TRPC6 mechanosensitivity.	TRPC1 TRPC6	1.54e-05	2	137	2	17957383
Pubmed	Two distinct secretory vesicle-priming steps in adrenal chromaffin cells.	CADPS CADPS2	1.54e-05	2	137	2	20855507
Pubmed	Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells.	RHCE RHD	1.54e-05	2	137	2	7789951
Pubmed	E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop.	RHCE RHD	1.54e-05	2	137	2	11724987
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	1.54e-05	2	137	2	31150793
Pubmed	The Rh blood group system: a review.	RHCE RHD	1.54e-05	2	137	2	10627438
Pubmed	CAPS facilitates filling of the rapidly releasable pool of large dense-core vesicles.	CADPS CADPS2	1.54e-05	2	137	2	18495893
Pubmed	The role of hERG1 K+ channels and a functional link between hERG1 K+ channels and SDF-1 in acute leukemic cell migration.	KCNH2 CXCL12	1.54e-05	2	137	2	19409379
Pubmed	[Increased activity of PRPP synthetase].	PRPS2 PRPS1	1.54e-05	2	137	2	18409517
Pubmed	Polymorphisms in the promoter regions of RHD and RHCE genes in the Chinese Han population.	RHCE RHD	1.54e-05	2	137	2	37823181
Pubmed	Sequence diversity of the Rh blood group system in Basques.	RHCE RHD	1.54e-05	2	137	2	30089826
Pubmed	Ether-à-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons.	KCNH7 KCNH2	1.54e-05	2	137	2	19359372
Pubmed	Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia.	RHCE RHD	1.54e-05	2	137	2	29193104
Pubmed	The multimeric structure of polycystin-2 (TRPP2): structural-functional correlates of homo- and hetero-multimers with TRPC1.	TRPC1 PKD2	1.54e-05	2	137	2	19193631
Pubmed	Critical role of TRPP2 and TRPC1 channels in stretch-induced injury of blood-brain barrier endothelial cells.	TRPC1 PKD2	1.54e-05	2	137	2	22192412
Pubmed	Feedback activation of neurofibromin terminates growth factor-induced Ras activation.	NF1 EGF	1.54e-05	2	137	2	26861207
Pubmed	RHCE variants inherited with altered RHD alleles in Brazilian blood donors.	RHCE RHD	1.54e-05	2	137	2	27111588
Pubmed	Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity.	RHCE RHD	1.54e-05	2	137	2	8822955
Pubmed	Genetic recombination at the human RH locus: a family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene.	RHCE RHD	1.54e-05	2	137	2	8808597
Pubmed	Molecular background of Rh D-positive, D-negative, D(el) and weak D phenotypes in Chinese.	RHCE RHD	1.54e-05	2	137	2	12201845
Pubmed	PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness.	PRPS2 PRPS1	1.54e-05	2	137	2	33493137
Pubmed	Variant RH alleles and Rh immunisation in patients with sickle cell disease.	RHCE RHD	1.54e-05	2	137	2	24960646
Pubmed	Comprehensive phenotypic and molecular investigation of RhD and RhCE variants in Moroccan blood donors.	RHCE RHD	1.54e-05	2	137	2	30418133
Pubmed	A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.	RHCE RHD	1.54e-05	2	137	2	23550903
Pubmed	Molecular cloning and primary structure of the human blood group RhD polypeptide.	RHCE RHD	1.54e-05	2	137	2	1438298
Pubmed	The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.	ARHGEF12 ARHGEF2	1.54e-05	2	137	2	21572419
Pubmed	Molecular background of D(C)(e) haplotypes within the white population.	RHCE RHD	1.54e-05	2	137	2	12084172
Pubmed	Tissue-differential expression of two distinct genes for phosphoribosyl pyrophosphate synthetase and existence of the testis-specific transcript.	PRPS2 PRPS1	1.54e-05	2	137	2	2537655
Pubmed	The analysis of nucleotide substitutions, gaps, and recombination events between RHD and RHCE genes through complete sequencing.	RHCE RHD	1.54e-05	2	137	2	10924335
Pubmed	A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.	RHCE RHD	1.54e-05	2	137	2	12857961
Pubmed	Specific amino acid substitutions cause distinct expression of JAL (RH48) and JAHK (RH53) antigens in RhCE and not in RhD.	RHCE RHD	1.54e-05	2	137	2	20233350
Pubmed	CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons.	CADPS CADPS2	1.54e-05	2	137	2	25719439
Pubmed	A recombination hot spot in the Rh genes revealed by analysis of unrelated donors with the rare D-- phenotype.	RHCE RHD	1.54e-05	2	137	2	8900235
Pubmed	RHDweak partial 4.0 is associated with an altered RHCEce(48C, 105T, 733G, 744C, 1025T) allele in the Tunisian population.	RHCE RHD	1.54e-05	2	137	2	23742316
Pubmed	A comprehensive survey of both RHD and RHCE allele frequencies in sub-Saharan Africa.	RHCE RHD	1.54e-05	2	137	2	24033223
Pubmed	Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production.	TRPC1 TRPC6	1.54e-05	2	137	2	23489970
Pubmed	DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.	DDX19B DDX19A	1.54e-05	2	137	2	30699353
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	NBEAL1 VPS13C SRP54 COPG2 NIBAN2 MUC13 ADCY9 VPS13D ANO6 VAMP4 EIF2AK3	1.66e-05	568	137	11	37774976
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CUL3 ARHGAP32 PPM1E NBEA ASAP2 CYFIP1 NF1 PPP3CB	1.67e-05	281	137	8	28706196
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ARHGAP32 NIBAN2 SLC1A4 ADCY9 CYFIP1 NF1 PTPRK ANO6 VAMP4	1.99e-05	377	137	9	38117590
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	PRPS2 UBR2 MYCBP2 NPEPPS VPS13C TM9SF3 SUCLA2	2.03e-05	209	137	7	26389662
Pubmed	Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.	TRPC1 TRPC6 PKDREJ PKD2	2.77e-05	44	137	4	19322198
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CUL3 ARHGAP32 MYCBP2 NPEPPS UBR4 ARHGEF12 NBEA WDR47 CYFIP1 NF1 PPP3CB ARHGEF2 SLC4A4 NIPBL	2.87e-05	963	137	14	28671696
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADGRV1 ADCY8 ADCY9	3.23e-05	16	137	3	17567809
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ARHGAP32 TUT4 KCNH7 MYCBP2 UBR4 NBEA SUCLA2 SLC1A4 WDR47 GMPS NF1 CADPS TENM1 SLC4A4 ATP5F1B	4.56e-05	1139	137	15	36417873
Pubmed	TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.	ARHGEF12 ARHGEF2	4.61e-05	3	137	2	25143398
Pubmed	TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization.	TRPC1 TRPC6	4.61e-05	3	137	2	19439599
Interaction	RHOB interactions	CUL3 UBR2 ARHGAP32 TM9SF3 ARHGEF12 NBEA NIBAN2 MUC13 ADCY9 FAM83B CKB CYFIP1 NF1 PTPRK ANO6 ADGRE5 ARHGEF2 IQGAP3	1.05e-05	840	133	18	int:RHOB
Interaction	RHOA interactions	CUL3 ARHGAP32 ARHGEF28 VPS13C TRPC1 ARHGAP26 TM9SF3 ARHGEF12 NIBAN2 MUC13 ADCY9 FAM83B VPS13D CYFIP1 NF1 PTPRK ANO6 ADGRE5 ARHGEF2 USP48 EIF2AK3 IQGAP3	1.19e-05	1199	133	22	int:RHOA
GeneFamily	CD molecules\|Adhesion G protein-coupled receptors, subfamily E	ADGRE5 ADGRE1	2.43e-04	5	90	2	915
GeneFamily	Transient receptor potential cation channels	TRPC1 TRPC6 PKD2	3.57e-04	28	90	3	249
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR2 UBR4	5.06e-04	7	90	2	785
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 NBEA	8.62e-04	9	90	2	1230
GeneFamily	Potassium voltage-gated channels	KCNH7 KCNH6 KCNH2	1.03e-03	40	90	3	274
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY8 ADCY9	1.07e-03	10	90	2	53
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP32 ARHGAP26 ARHGAP6	1.97e-03	50	90	3	721
GeneFamily	ATPase phospholipid transporting	ATP8B3 ATP10D	2.47e-03	15	90	2	1210
GeneFamily	Dyneins, axonemal	DNAH14 DNAH11	3.17e-03	17	90	2	536
Coexpression	GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN	ARHGAP32 VPS13C TRPC1 NBEA ATP10D TPCN1 PTPRK ALDH2	9.84e-06	199	136	8	M9236
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	UBR2 TUT4 MYCBP2 NPEPPS TRPC1 TRIM24 ADCY9 GMPS ASAP2 PPP3CB PTPRK MICAL2 PKD2 NIPBL CXCL12 CHST3	9.85e-06	856	136	16	M4500
Coexpression	GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP	ACSS1 PPM1E TPCN1 LIPH ADGRE5 ALDH2 EIF2AK3	1.21e-05	147	136	7	M6765
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	KNTC1 TUT4 NBEAL1 NPEPPS VPS13C PPM1E NF1	4.44e-05	180	136	7	M8239
Coexpression	DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN	NBEAL1 NBEA ADGRV1 SFMBT2 ATP10D HPS3 FAM83B PTPRK LIPH ANO6 ADGRF4	6.69e-05	504	136	11	M2157
Coexpression	GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP	TRPC1 GSDMB NBEA TRIM24 CKB URB1 SLC4A4	7.85e-05	197	136	7	M8980
Coexpression	LI_INDUCED_T_TO_NATURAL_KILLER_DN	ACSS1 TPCN1 ADGRE5 ALDH2 NIPBL CXCL12	8.23e-05	137	136	6	M2088
Coexpression	GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_UP	DDX19A SPATA2 SLC1A4 ADCY9 TPCN1 ARHGAP6 ASAP2	8.36e-05	199	136	7	M7474
Coexpression	LI_INDUCED_T_TO_NATURAL_KILLER_DN	ACSS1 TPCN1 ADGRE5 ALDH2 NIPBL CXCL12	8.57e-05	138	136	6	MM882
Coexpression	GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP	ARHGAP32 AHI1 SLC1A4 NF1 MCUR1 PKD2 ALDH2	8.63e-05	200	136	7	M3446
Coexpression	GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN	KNTC1 RILPL2 SLC1A4 CYFIP1 MICAL2 PKD2 STX11	8.63e-05	200	136	7	M3054
CoexpressionAtlas	kidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000	TRARG1 NBEAL1 TRPC1 ARHGAP26 TRPC6 ARHGEF12 ABCC9 NBEA ATP10D HPS3 NXPE3 ARHGAP6 ART3 PTPRK C1QTNF1 ADGRE5 ALDH2 DOCK6	4.47e-06	872	127	18	gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlas	Stem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2	KNTC1 ARHGAP32 TRPC6 ARHGEF12 NBEA MUC13 ADCY9 ADGRG7 ARHGAP6 PKD2 ALDH2 DOCK6	8.91e-06	422	127	12	GSM399442_500
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ADGRV1 DNAH14 SLC9C1 CELSR1 PTPRK LIPH MICAL2 SLC4A4 CADPS2	6.43e-10	199	137	10	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 TENM1 CACNA1H SLC4A4	3.87e-09	175	137	9	90e29945aa861082c94bb4f331161adc3a6ef899
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP32 AHI1 ARHGEF28 ADGRV1 TRIM24 CELSR1 MICAL2 SLC4A4 CADPS2	6.60e-09	186	137	9	e83718fabb057100835d3357df407f283d23fe16
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	NBEAL1 ADGRV1 DNAH14 CKB SLC9C1 PTPRK LIPH ARHGEF2 CADPS2	8.32e-09	191	137	9	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ADGRV1 ADCY9 DNAH14 CELSR1 PTPRK LIPH MICAL2 CADPS2	1.19e-08	199	137	9	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 TENM1 SLC4A4	7.60e-08	176	137	8	e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AHI1 NBEA ADGRV1 ODF2L CELSR1 GNA14 LIPH SLC4A4	7.60e-08	176	137	8	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ABCC9 ARHGAP6 TENM1 CACNA1H SLC4A4 CADPS2	8.66e-08	179	137	8	7954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 TENM1 SLC4A4	8.66e-08	179	137	8	f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCC9 ADGRV1 ADCY8 SLC9C1 PTPRK LIPH SLC4A4 CADPS2	1.03e-07	183	137	8	6847c1252d6bb105524f812658112517fd351eab
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 TRARG1 TRPC1 TRPC6 ADCY8 RLN1 ART3 C1QTNF1	1.07e-07	184	137	8	55dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 TRARG1 TRPC1 TRPC6 ADCY8 RLN1 ART3 C1QTNF1	1.07e-07	184	137	8	7128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 TRARG1 TRPC1 TRPC6 ADCY8 RLN1 ART3 C1QTNF1	1.07e-07	184	137	8	d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B KCNH7 CNTNAP3 KCNH6 CADPS KCNH2 SCN2A MARCHF11	1.26e-07	188	137	8	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRARG1 ACSS1 PPM1E ABCC9 GNA14 ART3 CACNA1H CXCL12	1.48e-07	192	137	8	88472b99970ba0decbf87164fc241a1c77b3b389
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP32 AHI1 ARHGAP26 COPG2 NBEA CADPS MICAL2 SCN2A	1.88e-07	198	137	8	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ARHGEF28 NBEA ADGRV1 CELSR1 EGF PTPRK LIPH	2.03e-07	200	137	8	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	AHI1 MYCBP2 COPG2 NBEA ODF2L CADPS MICAL2 SCN2A	2.03e-07	200	137	8	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	TM9SF3 BAG1 GSDMB ASAP2 LIPH ADGRE5 IQGAP3	6.31e-07	159	137	7	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRPC6 ABCC9 ADCY8 CKB ARHGAP6 ART3 SLC35F6	9.89e-07	170	137	7	1f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ABCC9 ARHGAP6 TENM1 SLC4A4 CADPS2	1.30e-06	177	137	7	bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 TRARG1 TRPC1 TRPC6 ADCY8 RLN1 ART3	1.40e-06	179	137	7	bfc226bcf0b93525992344f968268a261d86fcbf
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 TRARG1 TRPC1 TRPC6 ADCY8 RLN1 ART3	1.40e-06	179	137	7	36ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADCY8 ARHGAP6 TENM1 SLC4A4 CXCL12	1.45e-06	180	137	7	8f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B TRPC6 CNTNAP3 ABCC9 TENM1 SLC4A4 CADPS2	1.45e-06	180	137	7	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	E18.5-samps-Mesenchymal-Pericyte\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TRARG1 TRPC1 TRPC6 ABCC9 ART3 SLC35F6 C1QTNF1	1.45e-06	180	137	7	0b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	CNTNAP3B KCNH7 KCNH6 CADPS KCNH2 SCN2A MARCHF11	1.56e-06	182	137	7	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 TENM1	1.62e-06	183	137	7	65f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CNTNAP3B KCNH7 KCNH6 CADPS KCNH2 SCN2A MARCHF11	1.80e-06	186	137	7	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSS1 PPM1E ADGRV1 CKB ARHGAP6 EGF CXCL12	1.87e-06	187	137	7	7ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ADGRV1 SLC9C1 CELSR1 PTPRK LIPH MICAL2 DNAH11	1.93e-06	188	137	7	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP32 ARHGEF28 ADGRV1 CELSR1 MICAL2 SLC4A4 CADPS2	1.93e-06	188	137	7	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	NBEAL1 ADGRV1 DNAH14 SLC9C1 PTPRK MICAL2 SLC4A4	1.93e-06	188	137	7	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	ARHGEF28 NBEA ADGRV1 FAM83B CELSR1 SLC4A4 FAM83A	2.00e-06	189	137	7	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	NBEA ADGRV1 ODF2L CELSR1 GNA14 LIPH FAM83A	2.08e-06	190	137	7	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	ARHGEF28 NBEA ADGRV1 CELSR1 SLC4A4 CADPS2 FAM83A	2.08e-06	190	137	7	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	severe_COVID-19-RBC\|severe_COVID-19 / disease group, cell group and cell class (v2)	BAG1 ARHGEF12 RHCE RHD KCNH2 MICAL2 FAM83A	2.08e-06	190	137	7	3a5723c2daf58c1932edd70910db4b8b30f63f42
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC6 PPM1E ADAMTS8 GNA14 KCNH2 MICAL2 CACNA1H	2.15e-06	191	137	7	8e8beb8e8a3b33cac83d3f7ce915a71e3654fdab
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGRV1 DNAH14 CELSR1 PTPRK LIPH MICAL2 CADPS2	2.15e-06	191	137	7	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC6 PPM1E ADAMTS8 GNA14 KCNH2 MICAL2 CACNA1H	2.15e-06	191	137	7	60bc1f3efa7bbad5cb7944fe5e049ea79cd1745a
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	ADGRV1 DNAH14 CELSR1 PTPRK LIPH MICAL2 CADPS2	2.23e-06	192	137	7	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSS1 PPM1E ADGRV1 CKB ARHGAP6 EGF CXCL12	2.23e-06	192	137	7	562df5e87038c500dd3a003fe5374cb31946b145
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRARG1 NGB TRPC6 ABCC9 ADCY8 ART3 C1QTNF1	2.23e-06	192	137	7	dc4b4e16e6eb212e45fb70695afd1c7e91027407
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	ADGRV1 DNAH14 CELSR1 PTPRK LIPH MICAL2 CADPS2	2.23e-06	192	137	7	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADGRV1 ADCY8 DNAH14 PTPRK MICAL2 SLC4A4 CADPS2	2.23e-06	192	137	7	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRARG1 ABCC9 ADAMTS8 GNA14 ART3 CACNA1H CXCL12	2.30e-06	193	137	7	b9e11cd0896c0868aab7faec4ab7ab4d4e4d1b47
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	NBEA ADGRV1 ODF2L CELSR1 PTPRK LIPH CADPS2	2.30e-06	193	137	7	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-thrombocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CKB ARHGAP6 ASAP2 EGF LIPH ANO6 MCUR1	2.38e-06	194	137	7	7c38ead538695db1fb1c329ff67d2874aa83c8d2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NIBAN2 ADGRV1 ADCY9 PTPRK MICAL2 SLC4A4 CADPS2	2.38e-06	194	137	7	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-thrombocytic-platelet\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CKB ARHGAP6 ASAP2 EGF LIPH ANO6 MCUR1	2.38e-06	194	137	7	4531639974e363a6ff7ea688325a11407c3efd87
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRARG1 TRPC6 PPM1E ABCC9 GNA14 ART3 CACNA1H	2.38e-06	194	137	7	b8a130ffae68ffe550bf335460a1ec1035cf8d8d
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	ARHGEF12 NBEA GNA14 PTPRK LIPH CADPS2 DNAH11	2.47e-06	195	137	7	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	ARHGEF12 NBEA GNA14 PTPRK LIPH CADPS2 DNAH11	2.47e-06	195	137	7	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ADGRV1 DNAH14 SLC9C1 PTPRK LIPH MICAL2 CADPS2	2.47e-06	195	137	7	9406866f99555198a9be311fbd65751b70f35446
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGAP32 AHI1 ARHGEF28 ADGRV1 CELSR1 SLC4A4 CADPS2	2.73e-06	198	137	7	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NBEA ADGRV1 ODF2L CELSR1 LIPH SLC4A4 CADPS2	2.73e-06	198	137	7	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NBEA ADGRV1 ODF2L CELSR1 LIPH SLC4A4 CADPS2	2.73e-06	198	137	7	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRV1 DNAH14 SLC9C1 PTPRK LIPH MICAL2 SLC4A4	2.82e-06	199	137	7	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	PRPS2 VPS13C SRP54 ABCC9 ODF2L VPS13D NIPBL	2.82e-06	199	137	7	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRV1 DNAH14 PTPRK LIPH MICAL2 SLC4A4 CADPS2	2.82e-06	199	137	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	UBR2 ARHGAP32 ARHGEF28 ARHGAP26 NBEA NF1 CADPS2	2.82e-06	199	137	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP26 ACSS1 ADGRV1 SFMBT2 CKB GNA14 SLC4A4	2.91e-06	200	137	7	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP26 ACSS1 ADGRV1 SFMBT2 CKB GNA14 SLC4A4	2.91e-06	200	137	7	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Neuronal-Excitatory-eD(FEZF2)-ABO-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 SLC4A4	2.91e-06	200	137	7	e3051dcf9b5c8e4dc71a8080b7a7aafea46f2b2b
ToppCell	Neuronal-Excitatory-eD(FEZF2)-ABO--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 SLC4A4	2.91e-06	200	137	7	1ce9599cc9d8158e8842ca56f35fa7809c234849
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP26 ACSS1 ADGRV1 SFMBT2 CKB GNA14 SLC4A4	2.91e-06	200	137	7	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Neuronal-Excitatory-eD(FEZF2)-ABO---L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 SLC4A4	2.91e-06	200	137	7	7b845aabfbdfe893acc9334a5707833761bed60b
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP26 ACSS1 ADGRV1 SFMBT2 CKB GNA14 SLC4A4	2.91e-06	200	137	7	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Neuronal-Excitatory-eD(FEZF2)-ABO\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 SLC4A4	2.91e-06	200	137	7	0638273fc0910f47fe7a0b6d9a8639b0e9976d13
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	NBEAL1 TRPC6 ABCC9 NBEA ADAMTS8 SLC4A4 DOCK6	2.91e-06	200	137	7	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ARHGAP26 ACSS1 ADGRV1 SFMBT2 CKB GNA14 SLC4A4	2.91e-06	200	137	7	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ARHGEF28 TM9SF3 NBEA ADGRV1 EGF CADPS2	2.91e-06	200	137	7	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ATP10D QRFPR CACNA1H MARCHF11 LIX1 CXCL12	4.06e-06	136	137	6	1f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCell	Control-Epithelial_airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRV1 SLC1A4 FAM83B CELSR1 ADGRF4 DNAH11	9.59e-06	158	137	6	35aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACSS1 ADGRV1 CKB VPS13D EGF CXCL12	1.15e-05	163	137	6	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRPC6 CNTNAP3 ADAM32 RLN1 GNA14	1.25e-05	97	137	5	f3c3fb260954f594a9ab8e1ac9a01115767cbc7a
ToppCell	Control\|World / group, cell type (main and fine annotations)	ARHGEF28 ADGRV1 SLC9C1 PTPRK MICAL2 SLC4A4	1.36e-05	168	137	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC6 CNTNAP3 ABCC9 ARHGAP6 ASAP2 TENM1	1.36e-05	168	137	6	7abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythroid_lineage_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BAG1 CNTNAP3 RCVRN RHCE MICAL2 FAM83A	1.45e-05	170	137	6	288014dedda8babc51fe08e48a55e68d83e1b1d2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSS1 ADGRV1 DNAH14 CKB ARHGAP6 EGF	1.71e-05	175	137	6	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRARG1 TRPC1 TRPC6 ADCY8 KCNH6 ART3	1.71e-05	175	137	6	2a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRARG1 TRPC1 TRPC6 ADCY8 KCNH6 ART3	1.71e-05	175	137	6	fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC6 ABCC9 MICAL2 C1QTNF1 CACNA1H DNAH11	1.83e-05	177	137	6	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC6 ABCC9 MICAL2 C1QTNF1 CACNA1H DNAH11	1.83e-05	177	137	6	3645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B TRPC6 CNTNAP3 ABCC9 ARHGAP6 TENM1	1.89e-05	178	137	6	431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 NPEPPS NBEA ADGRV1 URB1 LIPH	1.95e-05	179	137	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	ARHGEF28 NBEA ODF2L CELSR1 SLC4A4 FAM83A	1.95e-05	179	137	6	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNH7 SGSM1 ARHGEF28 PPM1E SCN2A LIX1	1.95e-05	179	137	6	228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADCY8 TENM1 SLC4A4 MARCHF11	1.95e-05	179	137	6	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	facs-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRARG1 TRPC1 TRPC6 ADCY8 ART3 C1QTNF1	1.95e-05	179	137	6	7078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell	facs-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRARG1 TRPC1 TRPC6 ADCY8 ART3 C1QTNF1	1.95e-05	179	137	6	d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNH7 SGSM1 ARHGEF28 ADGRV1 SCN2A LIX1	1.95e-05	179	137	6	b8ca29aebd25ebac441bebd769bbf98c536d3166
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACSS1 ADGRV1 FAM83B EGF CACNA1H CADPS2	2.01e-05	180	137	6	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NBEA ADGRV1 CELSR1 GNA14 LIPH CADPS2	2.01e-05	180	137	6	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSS1 PPM1E ADGRV1 ARHGAP6 EGF CXCL12	2.01e-05	180	137	6	eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	ABCC9 ADGRV1 PTPRK MICAL2 SLC4A4 CADPS2	2.01e-05	180	137	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACSS1 PPM1E ADGRV1 ARHGAP6 EGF CXCL12	2.01e-05	180	137	6	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B TRPC6 CNTNAP3 ADCY8 ARHGAP6 TENM1	2.07e-05	181	137	6	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 ADCY8 TENM1 SLC4A4 CXCL12	2.07e-05	181	137	6	bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNH7 ARHGEF28 CNTNAP3 DNAH14 ART3 PTPRK	2.07e-05	181	137	6	9de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
Computational	Cell cycle (KEGG, GenMapp).	PRPS2 GMPS PRPS1	8.01e-05	12	79	3	MODULE_56
Drug	AC1L1TJF	ADCY8 ADCY9 CKB KCNH2 CACNA1I ADGRE5 CACNA1H	1.35e-07	66	136	7	CID000003377
Drug	lanthanum	TRPC1 TRPC6 ADCY8 ADCY9 TPCN1 PKD2 CACNA1I CACNA1H	1.63e-06	136	136	8	CID000023926
Drug	potassium	ATP8B3 KCNH7 NGB TRPC1 RCVRN ABCC9 SLC1A4 ADCY8 ADCY9 TPCN1 GMPS KCNH6 EGF ART3 KCNH2 SCN2A PKD2 CACNA1I CACNA1H SLC4A4	2.35e-06	1008	136	20	CID000000813
Drug	Cyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A	ARHGEF28 ARHGAP26 SLC1A4 ATP10D RLN1 VPS13D NF1 CACNA1I DOCK6	3.07e-06	198	136	9	6806_UP
Drug	Bay K 8644	ADCY8 ADCY9 TPCN1 NF1 ART3 PKD2 CACNA1I CACNA1H	3.40e-06	150	136	8	CID000002303
Drug	sodium	ATP8B3 KCNH7 TRPC1 TRPC6 SLC1A4 ADCY8 ADCY9 TPCN1 CKB GMPS KCNH6 EGF ART3 KCNH2 SCN2A PKD2 CACNA1H ALDH2 SLC4A4	3.52e-06	944	136	19	CID000000923
Drug	Doxazosin	KCNH7 KCNH6 KCNH2	4.12e-06	6	136	3	DB00590
Drug	Prazosin	KCNH7 KCNH6 KCNH2	4.12e-06	6	136	3	DB00457
Drug	Terazosin	KCNH7 KCNH6 KCNH2	4.12e-06	6	136	3	DB01162
Drug	guanine	PRPS2 ARHGEF28 MYCBP2 NGB FPR3 ARHGEF12 SRP54 ADCY8 ADCY9 GMPS NF1 GNA14 ART3 POLN ARHGEF2 DOCK6 IQGAP3 PRPS1	7.32e-06	902	136	18	CID000000764
Drug	verapamil	KCNH7 ABCC9 ADCY8 ADCY9 TPCN1 CKB KCNH6 EGF ART3 KCNH2 PKD2 CACNA1I CACNA1H	7.91e-06	490	136	13	CID000002520
Drug	D-myo-inositol-1,4,5-triphosphate	TRPC1 FPR3 TRPC6 ADCY8 ADCY9 TPCN1 GMPS PPP3CB EGF ART3 PKD2 CACNA1I CACNA1H SLC4A4	8.05e-06	568	136	14	CID000000806
Drug	Miconazole	KCNH7 KCNH6 KCNH2	1.14e-05	8	136	3	DB01110
Drug	pimozide	KCNH7 TPCN1 KCNH6 KCNH2 PKD2 CACNA1I CACNA1H	1.14e-05	127	136	7	CID000016362
Drug	NSC759576	ADCY8 ADCY9 TPCN1 CKB KCNH2 PKD2 CACNA1I CACNA1H	2.00e-05	191	136	8	CID000003075
Drug	Ibutilide	KCNH7 KCNH6 KCNH2	2.43e-05	10	136	3	DB00308
Drug	WAY-123,398	KCNH7 KCNH6 KCNH2	2.43e-05	10	136	3	CID000132160
Drug	Sulpiride [15676-16-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ARHGAP26 SLC1A4 ATP10D NXPE3 NF1 NPY4R KCNH2 DOCK6	2.49e-05	197	136	8	1467_UP
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A	AHI1 ARHGEF28 TRPC1 ADCY9 RLN1 VPS13D NF1 ARHGEF2	2.49e-05	197	136	8	7344_UP
Drug	Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; MCF7; HT_HG-U133A	AHI1 TRPC1 ARHGEF12 NCBP1 ADCY9 VPS13D NF1 CACNA1H	2.58e-05	198	136	8	7322_UP
Drug	nitrendipine	ADCY8 TPCN1 ART3 PKD2 CACNA1I CACNA1H	2.73e-05	98	136	6	CID000004507
Drug	DiC8	TRPC1 FPR3 TRPC6 ADCY8 ADCY9 EGF ART3	2.83e-05	146	136	7	CID000001323
Drug	nilvadipine	RCVRN TPCN1 PKD2 CACNA1I CACNA1H	2.96e-05	60	136	5	CID000004494
Drug	N-(1-(2,3-dimethoxyphenyl)-4-methyl-3-penten-1-yl)-1-(5-bromofurfuryl)-1-piperidyl-4-amine	KCNH6 KCNH2	3.54e-05	2	136	2	ctd:C531033
Drug	mibefradil	TRPC6 TPCN1 PKD2 CACNA1I CACNA1H	4.06e-05	64	136	5	CID000060662
Drug	Calcium	NGB TRPC1 TRPC6 NF1 EGF KCNH2 PKD2 CACNA1I CACNA1H ALDH2 EIF2AK3 CXCL12	4.16e-05	493	136	12	ctd:D002118
Drug	pyraclofos	KCNH7 KCNH6 KCNH2 SCN2A CACNA1I CACNA1H	4.25e-05	106	136	6	CID000093460
Drug	Dhga	PRPS2 CKB PRPS1	4.41e-05	12	136	3	CID000467478
Drug	AC1Q6T3B	PRPS2 GMPS CEPT1 PRPS1	5.52e-05	35	136	4	CID000000293
Drug	Mibefradil	KCNH2 CACNA1I CACNA1H	5.71e-05	13	136	3	ctd:D020748
Drug	lamotrigine	TPCN1 KCNH2 SCN2A PKD2 CACNA1I CACNA1H	7.04e-05	116	136	6	CID000003878
Drug	ethosuximide	TPCN1 PKD2 CACNA1I ADGRE5 CACNA1H	8.17e-05	74	136	5	CID000003291
Drug	papaverine	NGB ADCY8 ADCY9 KCNH2 PKD2 CACNA1I CACNA1H	9.25e-05	176	136	7	CID000004680
Drug	valproate	NGB ADGRV1 TRIM24 SFMBT2 TPCN1 KCNH2 PKD2 CACNA1I ADGRE5 CACNA1H	1.00e-04	381	136	10	CID000003121
Drug	nisoldipine	TPCN1 EGF PKD2 CACNA1I CACNA1H	1.05e-04	78	136	5	CID000004499
Drug	1,3-dioxoisoindoline-5-carboxamide	CACNA1I CACNA1H	1.06e-04	3	136	2	CID010679219
Drug	SureCN2398996	CACNA1I CACNA1H	1.06e-04	3	136	2	CID010220069
Drug	N-desmethylmethsuximide	CACNA1I CACNA1H	1.06e-04	3	136	2	CID000092154
Drug	bepridil	TPCN1 CKB KCNH2 PKD2 CACNA1I CACNA1H	1.11e-04	126	136	6	CID000002351
Drug	NSC7524	ADCY8 ADCY9 SCN2A PKD2 CACNA1I CACNA1H EIF2AK3	1.14e-04	182	136	7	CID000005657
Drug	amiloride	TRPC1 PKDREJ TPCN1 EGF ART3 PKD2 CACNA1I CACNA1H SLC4A4	1.19e-04	315	136	9	CID000016230
Drug	cobalt-60	ARHGAP32 NGB NPEPPS BAG1 ADCY8 ADCY9 TPCN1 PKD2 CACNA1I CACNA1H	1.21e-04	390	136	10	CID000061492
Drug	Zonisamide	SCN2A CACNA1I CACNA1H	1.33e-04	17	136	3	DB00909
Drug	guanosine 5'-diphosphate disodium salt	PRPS2 ARHGAP32 ARHGAP26 SRP54 ADCY8 ADCY9 GMPS ARHGAP6 NF1 GNA14 EGF ART3 PRPS1	1.40e-04	648	136	13	CID000000730
Drug	1 Em	TRPC1 TRPC6 ADCY8 ADCY9 EGF	1.41e-04	83	136	5	CID000446621
Drug	5253409; Up 200; 17uM; MCF7; HT_HG-U133A_EA	PPM1E SLC1A4 NXPE3 URB1 NF1 KCNH2 ADGRE5	1.49e-04	190	136	7	961_UP
Drug	baclofen	ADCY8 ADCY9 EGF ART3 PKD2 CACNA1I CACNA1H	1.54e-04	191	136	7	CID000002284
Drug	Clemastine fumarate [14976-57-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A	ARHGEF28 VPS13C SLC1A4 GNA14 KCNH2 MICAL2 SLC4A4	1.59e-04	192	136	7	7485_UP
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	PPM1E ARHGEF12 SLC1A4 EGF NPY4R DOCK6 USP48	1.64e-04	193	136	7	5914_UP
Drug	2gst	ADGRG7 PKD2 ADGRE5 ADGRF4 ADGRE1	1.67e-04	86	136	5	CID000444461
Drug	Mifepristone [84371-65-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	ARHGAP32 ARHGEF28 ARHGEF12 SPATA2 VPS13D NIPBL CHST3	1.80e-04	196	136	7	5827_DN
Drug	Paromomycin sulfate [1263-89-4]; Down 200; 5.6uM; MCF7; HT_HG-U133A	GSDMB SLC1A4 NF1 KCNH2 CACNA1H VAMP4 USP48	1.80e-04	196	136	7	4420_DN
Drug	guanosine 3',5'-cyclic monophosphoric acid	KNTC1 NGB RCVRN ADCY8 ADCY9 GMPS EGF ART3 KCNH2 PKD2 CACNA1I CACNA1H	1.83e-04	577	136	12	CID000000295
Drug	Theobromine [83-67-0]; Up 200; 22.2uM; MCF7; HT_HG-U133A	ARHGAP26 SLC1A4 EGF C1QTNF1 ARHGEF2 CXCL12 CHST3	1.86e-04	197	136	7	3334_UP
Drug	16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	AHI1 ARHGEF28 ARHGEF12 KCNH6 NF1 GNA14 ARHGEF2	1.86e-04	197	136	7	7546_DN
Drug	aspirin, USP; Down 200; 100uM; PC3; HT_HG-U133A	ARHGEF28 ARHGAP26 TPCN1 ARHGAP6 DOCK6 NIPBL CHST3	1.86e-04	197	136	7	1204_DN
Drug	Hdba	KCNH7 KCNH6 KCNH2	1.88e-04	19	136	3	CID000003896
Drug	MK-499	KCNH7 KCNH6 KCNH2	1.88e-04	19	136	3	CID000127718
Drug	Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; PC3; HT_HG-U133A	ARHGAP32 SPATA2 SLC1A4 ATP10D VPS13D SLC35F6 CHST3	1.92e-04	198	136	7	6353_DN
Drug	Pentoxifylline [6493-05-6]; Down 200; 14.4uM; PC3; HT_HG-U133A	TRPC1 ARHGEF12 SLC1A4 ATP10D VPS13D NF1 EGF	1.92e-04	198	136	7	7319_DN
Drug	Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A	AHI1 TRPC1 GSDMB VPS13D NF1 DOCK6 USP48	1.92e-04	198	136	7	7200_DN
Drug	Benzthiazide [91-33-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A	CUL3 ARHGEF28 SLC1A4 NXPE3 URB1 VPS13D NF1	1.92e-04	198	136	7	3329_UP
Drug	Gabexate mesilate [56974-61-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A	TRPC1 SLC1A4 RLN1 NF1 CACNA1H ARHGEF2 SLC4A4	1.92e-04	198	136	7	7357_UP
Drug	Fursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A	AHI1 TRPC1 NCBP1 ADCY9 VPS13D NF1 CACNA1H	1.92e-04	198	136	7	7349_UP
Drug	Naphazoline hydrochloride [550-99-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A	AHI1 TUT4 MUC13 NF1 ARHGEF2 SLC4A4 DOCK6	1.92e-04	198	136	7	1466_UP
Drug	8-bromo-cAMP	ADCY8 ADCY9 CKB GMPS NF1 EGF ART3 SLC4A4	1.93e-04	264	136	8	CID000001912
Drug	DNA-PK Inhibitor III; Down 200; 1uM; PC3; HT_HG-U133A	NCBP1 SLC1A4 KCNH6 NF1 TENM1 ALDH2 ARHGEF2	1.98e-04	199	136	7	7548_DN
Drug	gadolinium	TRPC1 TRPC6 ADGRV1 NF1 PKD2 CACNA1I CACNA1H	1.98e-04	199	136	7	CID000023982
Drug	Acemetacin [53164-05-9]; Down 200; 9.6uM; PC3; HT_HG-U133A	CUL3 SLC1A4 ATP10D VPS13D ALDH2 USP48 CHST3	1.98e-04	199	136	7	6361_DN
Drug	Drofenine hydrochloride [548-66-3]; Down 200; 11.4uM; PC3; HT_HG-U133A	ARHGAP32 TRPC1 ARHGAP26 NXPE3 VPS13D CELSR1 NIPBL	2.04e-04	200	136	7	7129_DN
Drug	Hydrocortisone base [50-23-7]; Down 200; 11uM; MCF7; HT_HG-U133A	UBR2 SLC1A4 URB1 ASAP2 PKD2 ARHGEF2 NIPBL	2.04e-04	200	136	7	5284_DN
Drug	Vitexin [3681-93-4]; Up 200; 9.2uM; PC3; HT_HG-U133A	AHI1 NCBP1 ADCY9 NF1 TENM1 CACNA1I DOCK6	2.04e-04	200	136	7	4588_UP
Drug	Rilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A	AHI1 ARHGAP26 SLC1A4 NXPE3 NF1 ALDH2 ARHGEF2	2.04e-04	200	136	7	5532_UP
Drug	AC1Q5TZX	NGB RCVRN ABCC9 KCNH2	2.09e-04	49	136	4	CID000004547
Drug	Amiodarone	KCNH2 CACNA1H	2.11e-04	4	136	2	DB01118
Drug	NS1643	KCNH6 KCNH2	2.11e-04	4	136	2	CID010177784
Drug	methsuximide	CACNA1I CACNA1H	2.11e-04	4	136	2	CID000006476
Drug	GTP[S]	TRPC1 FPR3 SRP54 NBEA ADCY8 ADCY9 TPCN1 GNA14 ART3 PKD2 CACNA1I CACNA1H	2.28e-04	591	136	12	CID000001764
Drug	AC1NUZ8M	TPCN1 EGF PKD2 CACNA1I CACNA1H	2.29e-04	92	136	5	CID000073211
Drug	pirenzepine	TRPC1 TRPC6 ADCY8 ADCY9 ART3	2.41e-04	93	136	5	CID000004848
Drug	1,3-DCG	TRPC1 TRPC6 ADCY8 ADCY9 RHCE	2.53e-04	94	136	5	CID000150911
Disease	long QT syndrome (implicated_via_orthology)	KCNH7 KCNH6 ARHGAP6 KCNH2	8.87e-08	10	136	4	DOID:2843 (implicated_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP3B ARHGAP32 TRPC1 CNTNAP3 NBEA SCN2A CADPS2	7.02e-06	152	136	7	DOID:0060041 (implicated_via_orthology)
Disease	Anemia, Hemolytic, Congenital	RHCE RHD	2.11e-05	2	136	2	C0002881
Disease	short QT syndrome (implicated_via_orthology)	KCNH6 KCNH2	6.31e-05	3	136	2	DOID:0050793 (implicated_via_orthology)
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13C VPS13D	6.31e-05	3	136	2	DOID:0111611 (implicated_via_orthology)
Disease	Rh Deficiency Syndrome	RHCE RHD	6.31e-05	3	136	2	C0272052
Disease	Rh-Null, Regulator Type	RHCE RHD	6.31e-05	3	136	2	C1849387
Disease	glucose measurement	SGSM1 MYCBP2 NPEPPS VPS13C BAG1 ADCY9 CACNA1I C1QTNF1 ALDH2	7.05e-05	380	136	9	EFO_0004468
Disease	Weight Gain	ARHGEF12 COPG2 VPS13D DNAH11 PRPS1	1.12e-04	102	136	5	C0043094
Disease	JUVENILE MYELOMONOCYTIC LEUKEMIA	ARHGAP26 NF1	1.26e-04	4	136	2	607785
Disease	Juvenile myelomonocytic leukemia	ARHGAP26 NF1	1.26e-04	4	136	2	cv:C0349639
Disease	acute myelomonocytic leukemia (is_implicated_in)	ARHGAP26 GMPS	1.26e-04	4	136	2	DOID:0081082 (is_implicated_in)
Disease	body weight	KNTC1 NBEAL1 VPS13C ARHGEF12 ADGRV1 TRIM24 ADCY9 DNAH14 QRFPR ODF2L CADPS KCNH2 POLN CADPS2 EIF2AK3 NIPBL	2.37e-04	1261	136	16	EFO_0004338
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	NF1 ADGRE5 ADGRE1	2.88e-04	28	136	3	DOID:1094 (implicated_via_orthology)
Disease	mammographic density percentage	NBEA ADAMTS8 ADCY8	3.21e-04	29	136	3	EFO_0006502
Disease	heart conduction disease (implicated_via_orthology)	KCNH7 KCNH6 KCNH2	4.31e-04	32	136	3	DOID:10273 (implicated_via_orthology)
Disease	juvenile myelomonocytic leukemia (is_implicated_in)	ARHGAP26 NF1	4.36e-04	7	136	2	DOID:0050458 (is_implicated_in)
Disease	Hodgkins lymphoma	AHI1 ARHGEF28 PTPRK CACNA1I	5.72e-04	82	136	4	EFO_0000183
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	5.80e-04	8	136	2	DOID:0060308 (implicated_via_orthology)
Disease	Generalized Epilepsy with Febrile Seizures Plus	ADGRV1 SCN2A	7.43e-04	9	136	2	C3502809
Disease	Liver Cirrhosis, Experimental	NBEA TRIM24 ATP10D GNA14 EGF ANO6 PKD2 ALDH2 SLC4A4 ADGRE1 CXCL12	9.44e-04	774	136	11	C0023893
Disease	epilepsy (implicated_via_orthology)	KCNH7 SLC1A4 KCNH6 KCNH2 SCN2A	9.73e-04	163	136	5	DOID:1826 (implicated_via_orthology)
Disease	Shortened QT interval	ABCC9 KCNH2	1.13e-03	11	136	2	C0151879
Disease	sciatic neuropathy (biomarker_via_orthology)	ABCC9 NF1 CACNA1I CACNA1H	1.16e-03	99	136	4	DOID:11446 (biomarker_via_orthology)
Disease	nicotine dependence (implicated_via_orthology)	TRPC1 TRPC6	1.35e-03	12	136	2	DOID:0050742 (implicated_via_orthology)
Disease	Autistic Disorder	AHI1 NBEA NF1 EGF CACNA1H CADPS2	1.36e-03	261	136	6	C0004352
Disease	Malignant neoplasm of breast	UBR4 PPM1E BAG1 GSDMB PKDREJ RHD NF1 EGF TENM1 ADGRF4 NIPBL CXCL12 PRPS1	1.42e-03	1074	136	13	C0006142
Disease	mammographic density measurement	NBEA ADAMTS8 ADCY8	1.60e-03	50	136	3	EFO_0005941
Disease	Ciliopathies	AHI1 ADGRV1 PKD2 DNAH11	1.71e-03	110	136	4	C4277690
Disease	multiple sclerosis	NLRP11 AHI1 NPEPPS ARHGAP26 ADCY8 SLC9B1 ASAP2 PTPRK USP48	1.78e-03	594	136	9	MONDO_0005301
Disease	nodular sclerosis Hodgkin lymphoma	AHI1 PTPRK	1.85e-03	14	136	2	EFO_0004708
Disease	RASopathy	ARHGAP26 NF1	2.13e-03	15	136	2	cv:C5555857
Disease	Dermatitis	EGF CXCL12	2.43e-03	16	136	2	C0011603
Disease	autism spectrum disorder (is_implicated_in)	AHI1 CYFIP1	2.43e-03	16	136	2	DOID:0060041 (is_implicated_in)
Disease	gout, hyperuricemia	PKD2 ALDH2	2.43e-03	16	136	2	EFO_0004274, EFO_0009104
Disease	platelet component distribution width	AHI1 NPEPPS RHCE RHD CKB CYFIP1 EGF ADGRE5 VAMP4 ATP5F1B	2.68e-03	755	136	10	EFO_0007984
Disease	high altitude adaptation	KNTC1 EXOC8	2.74e-03	17	136	2	EFO_0009105
Disease	Vascular Diseases	PKD2 ALDH2	2.74e-03	17	136	2	C0042373
Disease	serum IgG glycosylation measurement	VPS13C ADCY8 ASAP2 GNA14 EGF CADPS CACNA1I MARCHF11	3.01e-03	523	136	8	EFO_0005193
Disease	body surface area	KNTC1 ARHGAP26 ARHGEF12 ADCY9 ODF2L KCNH2 ALDH2 CADPS2 EIF2AK3	3.03e-03	643	136	9	EFO_0022196
Disease	Hypertrophy	TRPC6 RLN1	3.07e-03	18	136	2	C0020564
Disease	fat body mass	KCNH7 MYCBP2 ADCY8 CADPS SCN2A	3.39e-03	217	136	5	EFO_0005409
Disease	Juvenile Myelomonocytic Leukemia	ARHGAP26 NF1	3.43e-03	19	136	2	C0349639
Disease	diet measurement	CUL3 OR6B1 RILPL2 ACSS1 DNAH14 NF1 CADPS SCN2A CACNA1H ALDH2 NIPBL CXCL12	3.43e-03	1049	136	12	EFO_0008111
Disease	coronary artery disease	KCNH7 NBEAL1 ARHGAP26 ARHGEF12 SPATA2 FAM83B CKB ASAP2 C1QTNF1 ALDH2 DOCK6 USP48 CHST3	3.56e-03	1194	136	13	EFO_0001645
Disease	nephrotic syndrome	AHI1 GSDMB ADGRF4	4.35e-03	71	136	3	EFO_0004255

Protein segments in the cluster

Peptide	Gene	Start	Entry
NTLMAIFREVKEIIE	BHLHB9	531	Q6PI77
SEVVMNVLDVLTKLT	ADCY8	181	P40145
DVVVQELKSMVATKI	ACSS1	606	Q9NUB1
IVEVKLVDQDKTMFI	CFI	126	P05156
VKINREEAVVMVEVN	CNTNAP3	1106	Q9BZ76
KAVVLQTLAMGIVID	ERVK13-1	76	Q9NX77
QEAAIMDIVIKVSVA	EIF2AK3	301	Q9NZJ5
MQLVKQRLETVTEVI	AHI1	976	Q8N157
ALVKVLATAEVMVSQ	BPIFB4	496	P59827
NSINLMVVKVLIVED	ADAMTS8	261	Q9UP79
VLVLLMTDVLVFLQE	ARHGEF2	491	Q92974
MFSVFEEITRIVVKE	GSDMB	1	Q8TAX9
VTIQNVIKLVDELME	ADGRE5	296	P48960
DVVIIMRISKNVAIL	ADGRF4	596	Q8IZF3
FADKQVTAMIEITII	ADGRV1	3976	Q8WXG9
SVEVLSVVAVQVKMI	DNAH11	1951	Q96DT5
TIEQFMKILEEIDTL	BAG1	281	Q99933
ILQKVVMTAFADRTV	ABCC9	1486	O60706
SMIVTNKVIEIVGLA	ADAM32	206	Q8TC27
LLMNKLVVVIFISVV	ATP8B3	376	O60423
IVTANMILAVDIFDK	CELSR1	2241	Q9NYQ6
LISNVVMFITISIKV	ADGRG7	636	Q96K78
EAFQKEITMLPLVVV	ATP10D	116	Q9P241
MSVEQEILVTGIKVV	ATP5F1B	176	P06576
QIVAKIEEVLMTAQA	ARHGEF12	521	Q9NZN5
EIVSETLIAFMVKAV	CFAP206	26	Q8IYR0
LIEMLKQAAALVITV	POLN	211	Q7Z5Q5
LLEVVKQVKVSDMVE	NBEAL1	1846	Q6ZS30
IVIEKTELEVQIETM	ODF2L	291	Q9ULJ1
MIQVVDVIHAVEIIT	OR6K2	196	Q8NGY2
DDVTIKMIFAIVQII	QRFPR	306	Q96P65
TYEEVVLQTVMKDIL	NIBAN2	536	Q96TA1
DVIKRQDVIFELMQT	ARHGEF28	846	Q8N1W1
IAAKLAFIIVMEHVI	ANO6	831	Q4KMQ2
KSDVVLSFSLEVVIM	CADPS	391	Q9ULU8
EMITLLVAKFVTILE	CADPS	1176	Q9ULU8
IAVVMEELLKVVKSL	CYFIP1	926	Q7L576
EIIVSALVKILEANM	MCUR1	186	Q96AQ8
IAVLVDKMIRTQIVD	NCBP1	601	Q09161
KQVNVVLVVMVVAFA	NPY4R	261	P50391
EVELVQMVVDGVKLL	CKB	346	P12277
EFVKTIVDALMEVTV	NLRP11	556	P59045
LNVVDLIVDIMFIID	KCNH7	451	Q9NS40
VQELTKEIISEVQRM	ASAP2	416	O43150
TAVERLNVFITMAKV	FPR3	186	P25089
DLIVDIMFIVDILIN	KCNH2	456	Q12809
TVVDLIVDIMFVVDI	KCNH6	301	Q9H252
IVDIMFVVDIVINFR	KCNH6	306	Q9H252
IMIDQIASFIIQEII	FSIP2	4241	Q5CZC0
FLEDVITEMVKQLIF	FSIP2	5786	Q5CZC0
ARKVIALVMDIFTDV	FAM83B	146	Q5T0W9
FMVICNVAKILELVV	NIPBL	2041	Q6KC79
VVMELKEKAVIFIRE	KNTC1	1311	P50748
LLFPSVMVVVEQIKS	TUBGCP4	131	Q9UGJ1
VLVILMDVFTDVEIF	FAM83A	161	Q86UY5
LVKGLLSVEDMNVVV	LIPH	91	Q8WWY8
FMEVRIQSVVVEFIL	ARHGAP32	546	A7KAX9
MVLLESLVEIILVAV	EXOC8	641	Q8IYI6
ELFVAVEMLSAVVLI	IQGAP3	436	Q86VI3
RITKEFIMESVQEAV	LIX1	111	Q8N485
ITVIVVFLRDMNKAV	PPM1E	481	Q8WY54
AEESTAIIAVVQKMI	ARHGAP6	581	O43182
IDVTEVQIFIIIMHL	CEPT1	211	Q9Y6K0
EIPVEVVLKMVTEIK	GMPS	656	P49915
IMKNEEEVVILFAQV	C1QTNF1	211	Q9BXJ1
VVLDTLEIIVQTVML	DOCK6	1391	Q96HP0
QKVIVVAVCVVVLVM	EGF	1031	P01133
QEVETILDKAMVLFR	CUL3	406	Q13618
TAQFVLINVVVAVLM	CACNA1I	1716	Q9P0X4
IKVFVLDEADVMIAT	DDX19B	236	Q9UMR2
KMQQIEEVSILFADI	ADCY9	386	O60503
VVLSFTLEIVIMEVQ	CADPS2	361	Q86UW7
TLEIVIMEVQGLKSV	CADPS2	366	Q86UW7
TIKEMATISEDVIIV	COPG2	91	Q9UBF2
MAIEKRIGIFNVVVE	DNAH14	731	Q0VDD8
SITLVEKVQMIAVIL	MARCHF11	236	A6NNE9
QLMVELLKVFVVEAA	CENPX	36	A8MT69
KVFVLDEADVMIATQ	DDX19A	236	Q9NUU7
KDIKVVIPVVSVQMI	GRAMD2A	121	Q8IUY3
VAQFVLVNVVVAVLM	CACNA1H	1846	O95180
VGEKVTEMLVNVLSI	PPP3CB	366	P16298
ISTVEVLKVMEAFVN	NPEPPS	631	P55786
RKVMLVIDAAVTNVE	NGB	66	Q9NPG2
VTQLQFKVVRVLEML	RILPL2	61	Q969X0
FKVVRVLEMLEALVN	RILPL2	66	Q969X0
VKINREEAVVMVEVN	CNTNAP3B	1106	Q96NU0
VFTELMQVIEQRDKL	MICAL2	1911	O94851
IVVEMVKRQNVVDVF	PTPRK	1391	Q15262
MEQVNKTVVREFVVL	OR10K1	1	Q8NGX5
AQIIREVEVDKVSML	GNA14	106	O95837
ETVFFIQQMKIIVIS	TEX47	121	Q8TBZ9
TIINEEVLNAMLKEV	SRP54	21	P61011
DEVIDVMQENITKVI	VAMP4	61	O75379
IAVTVKTKEEINVML	SLC9C1	801	Q4G0N8
SIVAVELELKDFMNV	HPS3	966	Q969F9
AVLMVVVLVINVTQV	NXPE3	16	Q969Y0
FINKDTETIIIMLEF	RLN1	76	P04808
TISKNEVLEIVMAIF	RCVRN	116	P35243
EVLVHIVTEVMVLFT	PKDREJ	996	Q9NTG1
EVGLIEQVLLKMSAV	NBEA	156	Q8NFP9
VEVLVSVLVGLAMEV	MT-ND6	86	P03923
AIMDIKFQNIVIEIL	ARHGAP26	546	Q9UNA1
NQFIVVEKVTMQRVV	TENM1	956	Q9UKZ4
MIRKIDENAVITTVI	TENM1	1326	Q9UKZ4
TSFREVLEKMLVIVV	MYCBP2	1656	O75592
MELENQTRVTKFILV	OR6B1	1	O95007
QVKEALVDLMLTVVE	URB1	1501	O60287
VIAQGIVMAVKDLEI	SUCLA2	386	Q9P2R7
EAVILFLMVRNLKVV	ADGRE1	686	Q14246
VMQILKFKTIEEVVG	ALDH2	421	P05091
VVIVFVFIEKENKII	CHST3	31	Q7LGC8
VVVVIVLTKLLVAML	TRPC1	631	P48995
MTAEETVNVKEVEII	WDR47	1	O94967
EQDIKVAIFTLMVEI	TRIM24	306	O15164
RELVETLQVKMVSFE	SPATA2	151	Q9UM82
LAQLVVMVLVEVTAL	RHD	136	Q02161
LAQLVVMVLVEVTAL	RHCE	136	P18577
MRADDKFVNVTIVTI	MUC13	276	Q9H3R2
IVEMKDIIVLVTSLG	SLC1A4	281	P43007
MAVLVEKQADTLNVI	STX11	231	O75558
KIQVIDISMILAEAI	PRPS2	286	P11908
DFVTKQVFDISIMIL	SCN2A	1526	Q99250
VLVLKEVLSMIINAA	SFMBT2	561	Q5VUG0
VIFLLVQSMVVDLKN	NF1	341	P21359
KQVNVVLVVMVVAFA	NPY4R2	261	P0DQD5
DIINMLLNFEIKEVV	VPS13C	1421	Q709C8
AKDVMTVAFLAILIT	SLC9B1	466	Q4ZJI4
EVKQIMEEAVTRKFV	SGSM1	21	Q2NKQ1
IVSKIDAVIVKLEIM	PKD2	856	Q13563
AQIIVAIQMVLEEKF	SLC35F6	186	Q8N357
VVQFVEAIVVLVRQM	TPCN1	181	Q9ULQ1
IFAVSLIVIIVAMIE	TM9SF3	301	Q9HD45
LGFIVVVVEVMKTAL	TMEM253	106	P0C7T8
KIQVIDISMILAEAI	PRPS1	286	P60891
VTILIFMDQQITAVI	SLC4A4	791	Q9Y6R1
IVIIMVAVTVNFTVQ	TRARG1	161	Q8IXB3
QIQSDIIEIIKTEML	ZMYM1	616	Q5SVZ6
IIEIIKTEMLQDIVN	ZMYM1	621	Q5SVZ6
QTMAVKFLVVLAVAI	TRPC6	401	Q9Y210
MNAKVVVVLVLVLTA	CXCL12	1	P48061
RQEIVEEMSKVITTF	TUT4	376	Q5TAX3
LITEENLMSIIIKTF	UBR2	431	Q8IWV8
EVKVESRAMVLAAFV	UBR2	1116	Q8IWV8
LFLMAVNIKTPVVVE	UBR4	3996	Q5T4S7
AAVAEQVLSIMEIIL	UBR4	4556	Q5T4S7
MIQKLFVVDHVIKIT	USP48	806	Q86UV5
VVEGMFIIVNSITIK	UHRF1BP1	121	Q6BDS2
MITAQRFTVQIEEKL	VPS13D	3931	Q5THJ4
MILVDIFQVKAEVLD	ART3	16	Q13508