Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone binding	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 TRIM24 TAF1L	5.16e-07	265	73	9	GO:0042393
GeneOntologyBiologicalProcess	gonadal mesoderm development	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	2.05e-16	9	74	7	GO:0007506
GeneOntologyBiologicalProcess	protein-DNA complex assembly	TSPY4 TSPY3 TSPY10 HMGB1 TSPY2 TSPY9 TSPY8 TSPY1 TAF1L	2.63e-07	249	74	9	GO:0065004
GeneOntologyBiologicalProcess	nucleosome assembly	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	2.76e-07	122	74	7	GO:0006334
GeneOntologyBiologicalProcess	spermatogenesis	TDRD7 LRGUK CSNK2A2 EPC1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 SPAG17 RNF17 DNAJA1	3.43e-07	744	74	14	GO:0007283
GeneOntologyBiologicalProcess	male gamete generation	TDRD7 LRGUK CSNK2A2 EPC1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 SPAG17 RNF17 DNAJA1	4.57e-07	762	74	14	GO:0048232
GeneOntologyBiologicalProcess	nucleosome organization	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	7.74e-07	142	74	7	GO:0034728
GeneOntologyBiologicalProcess	mesoderm development	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.52e-06	157	74	7	GO:0007498
GeneOntologyBiologicalProcess	chromatin remodeling	TET2 PBRM1 EPC1 TSPY4 PAXIP1 TSPY3 TSPY10 HMGB1 TSPY2 TSPY9 TSPY8 TSPY1 TAF1L	2.07e-06	741	74	13	GO:0006338
GeneOntologyBiologicalProcess	chromatin organization	TET2 EYA4 PBRM1 EPC1 TSPY4 PAXIP1 TSPY3 TSPY10 HMGB1 TSPY2 TSPY9 TSPY8 TSPY1 TAF1L	3.09e-06	896	74	14	GO:0006325
GeneOntologyBiologicalProcess	gamete generation	TDRD7 LRGUK CSNK2A2 EPC1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 SPAG17 RNF17 DNAJA1	8.84e-06	982	74	14	GO:0007276
GeneOntologyBiologicalProcess	gonad development	TGFB2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	9.83e-06	292	74	8	GO:0008406
GeneOntologyBiologicalProcess	protein-DNA complex organization	TET2 EYA4 PBRM1 EPC1 TSPY4 PAXIP1 TSPY3 TSPY10 HMGB1 TSPY2 TSPY9 TSPY8 TSPY1 TAF1L	1.07e-05	999	74	14	GO:0071824
GeneOntologyBiologicalProcess	development of primary sexual characteristics	TGFB2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.11e-05	297	74	8	GO:0045137
GeneOntologyBiologicalProcess	nucleoside monophosphate metabolic process	LRGUK ADSL NT5E NT5C3A DUT	1.61e-05	88	74	5	GO:0009123
GeneOntologyBiologicalProcess	multicellular organismal reproductive process	TDRD7 TGFB2 LRGUK CSNK2A2 EPC1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 SPAG17 RNF17 DNAJA1	1.82e-05	1194	74	15	GO:0048609
GeneOntologyBiologicalProcess	developmental process involved in reproduction	TDRD7 TGFB2 LRGUK CSNK2A2 EPC1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 SPAG17 RNF17 DNAJA1	2.70e-05	1235	74	15	GO:0003006
GeneOntologyBiologicalProcess	sex differentiation	TGFB2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	3.76e-05	352	74	8	GO:0007548
GeneOntologyBiologicalProcess	mesenchyme development	TGFB2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	5.55e-05	372	74	8	GO:0060485
GeneOntologyBiologicalProcess	reproductive structure development	TGFB2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	6.80e-05	383	74	8	GO:0048608
GeneOntologyBiologicalProcess	reproductive system development	TGFB2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	7.44e-05	388	74	8	GO:0061458
GeneOntologyBiologicalProcess	ribonucleoside monophosphate metabolic process	LRGUK ADSL NT5E NT5C3A	9.86e-05	67	74	4	GO:0009161
GeneOntologyBiologicalProcess	sexual reproduction	TDRD7 LRGUK CSNK2A2 EPC1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 SPAG17 RNF17 DNAJA1	2.06e-04	1312	74	14	GO:0019953
GeneOntologyBiologicalProcess	dUMP metabolic process	NT5C3A DUT	3.51e-04	8	74	2	GO:0046078
GeneOntologyBiologicalProcess	external encapsulating structure organization	TGFB2 TGM1 COL12A1 COLGALT2 MMP12 MMP26 ATXN1L	4.18e-04	379	74	7	GO:0045229
GeneOntologyBiologicalProcess	regulation of vitamin D receptor signaling pathway	SNW1 TRIM24	5.61e-04	10	74	2	GO:0070562
GeneOntologyBiologicalProcess	pyrimidine-containing compound catabolic process	TET2 NT5C3A DUT	6.02e-04	46	74	3	GO:0072529
GeneOntologyCellularComponent	manchette	LRGUK SPAG17 DYNC1H1	1.26e-04	28	73	3	GO:0002177
GeneOntologyCellularComponent	chromatin	PBRM1 SNW1 CSNK2A2 EPC1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 ELK3 TSPY8 BRMS1L TSPY1 TRIM24 TAF1L	1.53e-04	1480	73	15	GO:0000785
MousePheno	lethargy	NT5E CC2D2A HMGB1 ATXN1L ATP2B2	4.44e-05	100	55	5	MP:0005202
MousePheno	abnormal alertness	NT5E CC2D2A HMGB1 ATXN1L ATP2B2	4.44e-05	100	55	5	MP:0020222
MousePheno	decreased alertness	NT5E CC2D2A HMGB1 ATXN1L ATP2B2	4.44e-05	100	55	5	MP:0020224
Domain	NAP	TSPY4 TSPY10 TSPY2 TSPY8	3.91e-07	17	69	4	PF00956
Domain	NAP_family	TSPY4 TSPY10 TSPY2 TSPY8	3.91e-07	17	69	4	IPR002164
Domain	HMG_box_2	SP100 HMGB1 HMGXB3	3.99e-06	9	69	3	PF09011
Domain	HMG_box	SP100 PBRM1 HMGB1 HMGXB3	4.36e-05	53	69	4	PF00505
Domain	HMG_BOX_2	SP100 PBRM1 HMGB1 HMGXB3	4.69e-05	54	69	4	PS50118
Domain	HMG	SP100 PBRM1 HMGB1 HMGXB3	4.69e-05	54	69	4	SM00398
Domain	-	SP100 PBRM1 HMGB1 HMGXB3	5.05e-05	55	69	4	1.10.30.10
Domain	HMG_box_dom	SP100 PBRM1 HMGB1 HMGXB3	9.75e-05	65	69	4	IPR009071
Domain	Bromodomain_CS	PBRM1 TRIM24 TAF1L	1.18e-04	26	69	3	IPR018359
Domain	BROMODOMAIN_1	PBRM1 TRIM24 TAF1L	3.43e-04	37	69	3	PS00633
Domain	Bromodomain	PBRM1 TRIM24 TAF1L	3.71e-04	38	69	3	PF00439
Domain	BROMODOMAIN_2	PBRM1 TRIM24 TAF1L	4.65e-04	41	69	3	PS50014
Domain	BROMO	PBRM1 TRIM24 TAF1L	5.00e-04	42	69	3	SM00297
Domain	Bromodomain	PBRM1 TRIM24 TAF1L	5.00e-04	42	69	3	IPR001487
Domain	-	PBRM1 TRIM24 TAF1L	5.00e-04	42	69	3	1.20.920.10
Domain	TUDOR	TDRD7 RNF17	1.19e-03	14	69	2	PF00567
Domain	HAD-like_dom	EYA4 NT5C3A ATP2B2	3.12e-03	79	69	3	IPR023214
Domain	M10A_MMP	MMP12 MMP26	3.24e-03	23	69	2	IPR033739
Domain	TUDOR	TDRD7 RNF17	3.24e-03	23	69	2	PS50304
Domain	Pept_M10A	MMP12 MMP26	3.24e-03	23	69	2	IPR021190
Domain	Peptidase_M10	MMP12 MMP26	3.52e-03	24	69	2	PF00413
Domain	BRCT	ENGASE PAXIP1	4.13e-03	26	69	2	PS50172
Domain	TUDOR	TDRD7 RNF17	4.45e-03	27	69	2	SM00333
Domain	BRCT_dom	ENGASE PAXIP1	4.78e-03	28	69	2	IPR001357
Domain	ZnMc	MMP12 MMP26	5.12e-03	29	69	2	SM00235
Domain	Peptidase_Metallo	MMP12 MMP26	5.12e-03	29	69	2	IPR006026
Domain	Tudor	TDRD7 RNF17	5.47e-03	30	69	2	IPR002999
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TET2 PBRM1 VRK3 CSNK2A2 EPC1 PAXIP1 TRIM24 DNAJA1 RPL6	1.98e-07	398	75	9	35016035
Pubmed	Human transcription factor protein interaction networks.	TET2 EYA4 PBRM1 SNW1 CSNK2A2 EPC1 PAXIP1 HMGB1 ELK3 BRMS1L TRIM24 DNAJA1 ATXN1L TAF1L DYNC1H1	3.34e-07	1429	75	15	35140242
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 EYA4 PBRM1 EPC1 PAXIP1 BRMS1L TRIM24 ATXN1L	9.31e-07	351	75	8	38297188
Pubmed	An Exceptional Gene: Evolution of the TSPY Gene Family in Humans and Other Great Apes.	TSPY9 TSPY1	4.59e-06	2	75	2	24710137
Pubmed	Novel mutations in TGM1 and ABCA12 cause autosomal recessive congenital ichthyosis in five Saudi families.	TGM1 ABCA12	4.59e-06	2	75	2	27061915
Pubmed	Structure and function of TSPY, the Y-chromosome gene coding for the "testis-specific protein".	TSPY9 TSPY1	4.59e-06	2	75	2	9678360
Pubmed	Battle of the sexes: contrasting roles of testis-specific protein Y-encoded (TSPY) and TSPX in human oncogenesis.	TSPY9 TSPY1	4.59e-06	2	75	2	29974883
Pubmed	TSPY, the candidate gonadoblastoma gene on the human Y chromosome, has a widely expressed homologue on the X - implications for Y chromosome evolution.	TSPY9 TSPY1	4.59e-06	2	75	2	15241014
Pubmed	TSPY-related sequences represent a microheterogeneous gene family organized as constitutive elements in DYZ5 tandem repeat units on the human Y chromosome.	TSPY9 TSPY1	4.59e-06	2	75	2	8244388
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	UBE4A PBRM1 SNW1 ADSL CSNK2A2 DUT CC2D2A HMGB1 ECPAS DNAJA1 RPL6 DYNC1H1 PDXK	1.03e-05	1425	75	13	30948266
Pubmed	AHR/TET2/NT5E axis downregulation is associated with the risk of systemic lupus erythematosus and its progression.	TET2 NT5E	1.37e-05	3	75	2	36314527
Pubmed	Summary of mutations underlying autosomal recessive congenital ichthyoses (ARCI) in Arabs with four novel mutations in ARCI-related genes from the United Arab Emirates.	TGM1 ABCA12	1.37e-05	3	75	2	28236338
Pubmed	Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2. Cloning, expression, and site-directed mutagenesis of inhibitor-2.	PPP1R2 CSNK2A2	1.37e-05	3	75	2	8288648
Pubmed	Structural basis for regulation of protein phosphatase 1 by inhibitor-2.	PPP1R2 PPP1R2P1	1.37e-05	3	75	2	17636256
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UBE4A TGM1 EYA4 VRK3 EPC1 BRMS1L ECPAS TRIM24 DYNC1H1 XPO7	1.53e-05	857	75	10	25609649
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TET2 PBRM1 EPC1 PAXIP1 TRIM24 ATXN1L	2.55e-05	268	75	6	33640491
Pubmed	Cloning and characterization of human phosphatase inhibitor-2 (IPP-2) sequences.	PPP1R2 PPP1R2P1	2.75e-05	4	75	2	7949733
Pubmed	Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages.	HMGB1 MMP12	2.75e-05	4	75	2	32855420
Pubmed	Association between polymorphisms of matrix metalloproteinase 11 (MMP-11) and Kawasaki disease in the Korean population.	MMP12 MMP26	2.75e-05	4	75	2	20230842
Pubmed	Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH2-domain mediated interactions.	EPHB3 RASA1	2.75e-05	4	75	2	9674711
Pubmed	Protein kinase CK2 regulates the formation and clearance of aggresomes in response to stress.	CSNK2A2 DYNC1H1	4.57e-05	5	75	2	21486957
Pubmed	Regulators of the protein phosphatase PP1γ2, PPP1R2, PPP1R7, and PPP1R11 are involved in epididymal sperm maturation.	PPP1R2 PPP1R2P1	4.57e-05	5	75	2	30144392
Pubmed	Protein Phosphatase-1 Inhibitor-2 Is a Novel Memory Suppressor.	PPP1R2 PPP1R2P1	4.57e-05	5	75	2	26558779
Pubmed	Common properties of nuclear body protein SP100 and TIF1alpha chromatin factor: role of SUMO modification.	SP100 TRIM24	4.57e-05	5	75	2	11313457
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PBRM1 SNW1 CSNK2A2 ECPAS DNAJA1 RPL6 DYNC1H1 XPO7	8.26e-05	653	75	8	22586326
Pubmed	Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.	PPP1R2 PPP1R2P1	9.57e-05	7	75	2	18689497
Pubmed	EphB regulates L1 phosphorylation during retinocollicular mapping.	CHL1 EPHB3	9.57e-05	7	75	2	22579729
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	EYA4 PBRM1 SNW1 VRK3 EPC1 PAXIP1 HMGB1 BRMS1L DNAJA1 TAF1L RPL6	1.00e-04	1294	75	11	30804502
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	PBRM1 SNW1 ECPAS TRIM24 DNAJA1	1.17e-04	220	75	5	35785414
Pubmed	Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis.	PPP1R2 PPP1R2P1	1.27e-04	8	75	2	36693320
Pubmed	TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis.	TGFB2 ELK3	1.27e-04	8	75	2	36696357
Pubmed	High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.	PAXIP1 NSUN7	1.27e-04	8	75	2	21118569
Pubmed	Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme.	PCDH15 ATP2B2	1.64e-04	9	75	2	35296311
Pubmed	Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations.	PAXIP1 NSUN7	1.64e-04	9	75	2	16024820
Pubmed	Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.	PCDH15 ATP2B2	1.64e-04	9	75	2	19339464
Pubmed	Protein profile of exosomes from trabecular meshwork cells.	COL12A1 NT5E DYNC1H1	1.65e-04	49	75	3	21362503
Pubmed	The in vivo brain interactome of the amyloid precursor protein.	PPP1R2 PPP1R2P1 ATP2B2	1.76e-04	50	75	3	17934213
Pubmed	The C-terminal domain phosphatase and transcription elongation activities of FCP1 are regulated by phosphorylation.	CSNK2A2 HMGB1	2.04e-04	10	75	2	12591939
Pubmed	Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization.	DNAJA1 DYNC1H1	2.04e-04	10	75	2	19826009
Pubmed	Recruitment and maintenance of tendon progenitors by TGFbeta signaling are essential for tendon formation.	TGFB2 COL12A1	2.04e-04	10	75	2	19304887
Pubmed	Strain background effects and genetic modifiers of hearing in mice.	PCDH15 ATP2B2	2.49e-04	11	75	2	16579977
Pubmed	Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.	TGFB2 MMP12	2.49e-04	11	75	2	24621683
Pubmed	CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.	EPS8L2 PCDH15	2.99e-04	12	75	2	28663585
Pubmed	Genome-wide association identifies regulatory Loci associated with distinct local histogram emphysema patterns.	TGFB2 MMP12	2.99e-04	12	75	2	25006744
Pubmed	Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene.	TGFB2 TGM1	2.99e-04	12	75	2	10984614
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PPP1R2 TGFB2 SNW1 ADSL VRK3 NT5E HMGB1 DNAJA1 RPL6 DYNC1H1	3.38e-04	1247	75	10	27684187
Pubmed	Autosomal Recessive Congenital Ichthyosis	TGM1 ABCA12	3.52e-04	13	75	2	20301593
Pubmed	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	TET2 TAF1L	4.73e-04	15	75	2	22658931
Pubmed	Genetic Hearing Loss Overview	EYA4 PCDH15 ATP2B2	4.75e-04	70	75	3	20301607
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	SP100 PBRM1 TRIM24	5.82e-04	75	75	3	25593309
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TET2 SNW1 CSNK2A2 PAXIP1 HMGB1 ECPAS TRIM24 ATXN1L DYNC1H1	6.04e-04	1103	75	9	34189442
Pubmed	E2F6 associates with BRG1 in transcriptional regulation.	PBRM1 EPC1	6.11e-04	17	75	2	23082233
Pubmed	Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium.	TGFB2 MMP12	6.11e-04	17	75	2	34622152
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SP100 PBRM1 ABCA12 CSNK2A2 EPC1 AOX1 BRMS1L TRIM24 DNAJA1	6.57e-04	1116	75	9	31753913
Pubmed	ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization.	MMP12 ATXN1L	7.66e-04	19	75	2	22014525
Pubmed	Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.	TGM1 DNAJA1 DYNC1H1	8.10e-04	84	75	3	29563501
Pubmed	A quantitative survey of gravity receptor function in mutant mouse strains.	PCDH15 ATP2B2	8.50e-04	20	75	2	16235133
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	TET2 EPS8L2 ADSL HMGB1 ECPAS RPL6 DYNC1H1	8.63e-04	711	75	7	33022573
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	ADSL RPL6 DYNC1H1 PDXK XPO7	9.01e-04	344	75	5	30333137
Pubmed	Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling component BAF180.	TGFB2 PBRM1	9.38e-04	21	75	2	18508041
Pubmed	Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.	SNW1 NT5E RPL6	9.89e-04	90	75	3	31280863
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	PBRM1 DNAJA1 TAF1L DYNC1H1	9.91e-04	203	75	4	22083510
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	UBE4A VRK3 CSNK2A2 NT5C3A DUT HMGB1 ECPAS DNAJA1 DYNC1H1 PDXK	1.03e-03	1440	75	10	30833792
Pubmed	Genome-wide, large-scale production of mutant mice by ENU mutagenesis.	TDRD7 DYNC1H1	1.03e-03	22	75	2	10932192
Pubmed	Matrix metalloproteinases.	MMP12 MMP26	1.03e-03	22	75	2	10419448
Pubmed	Kir2.1 Interaction with Stk38 Promotes Invasion and Metastasis of Human Gastric Cancer by Enhancing MEKK2-MEK1/2-ERK1/2 Signaling.	UBE4A HMGB1	1.03e-03	22	75	2	29549164
Pubmed	The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs.	RASA1 RPL6	1.33e-03	25	75	2	15121898
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PBRM1 SNW1 CSNK2A2 HMGB1 ECPAS DNAJA1 PDXK XPO7	1.53e-03	1014	75	8	32416067
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	EYA4 SNW1 PAXIP1 BRMS1L DNAJA1 ATXN1L	1.64e-03	583	75	6	29844126
Pubmed	Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.	TGFB2 COL12A1	1.67e-03	28	75	2	28159809
Pubmed	Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.	NT5E DYNC1H1	1.67e-03	28	75	2	35227662
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	PBRM1 PAXIP1 PCDH15 ECPAS TRIM24	1.68e-03	396	75	5	26687479
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	SNW1 DUT HMGB1 DNAJA1 PDXK	1.73e-03	399	75	5	35987950
Pubmed	Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.	PAXIP1 HMGB1 DYNC1H1	1.81e-03	111	75	3	21163940
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	EPS8L2 COL12A1 CSNK2A2 TRMT11 HMGB1 DNAJA1 RPL6 DYNC1H1 PDXK	1.87e-03	1297	75	9	33545068
Pubmed	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	TGFB2 TET2	1.92e-03	30	75	2	21946350
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	PTGES2 ADSL CSNK2A2 HMGB1 ECPAS DNAJA1	2.00e-03	607	75	6	39147351
Pubmed	Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).	COL12A1 MMP12 RPL6 DYNC1H1	2.03e-03	247	75	4	39238192
Pubmed	Microarray analysis of the Df1 mouse model of the 22q11 deletion syndrome.	PPP1R2 PPP1R2P1	2.05e-03	31	75	2	15778864
Pubmed	STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1.	DNAJA1 DYNC1H1	2.05e-03	31	75	2	28089446
Pubmed	Nucleolar proteome dynamics.	SNW1 CSNK2A2 DNAJA1 RPL6 DYNC1H1	2.14e-03	419	75	5	15635413
Pubmed	A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.	UBE4A RNF17 TRIM24	2.15e-03	118	75	3	19690564
Interaction	TSPY8 interactions	TSPY3 TSPY2 TSPY8	4.01e-08	3	70	3	int:TSPY8
Interaction	HNF1B interactions	TET2 EYA4 PBRM1 EPC1 PAXIP1 BRMS1L TRIM24 ATXN1L	3.09e-07	190	70	8	int:HNF1B
Interaction	SP7 interactions	TET2 EYA4 PBRM1 CSNK2A2 EPC1 PAXIP1 BRMS1L TRIM24 ATXN1L	1.04e-06	304	70	9	int:SP7
Interaction	LHX3 interactions	PBRM1 PAXIP1 TSPY2 BRMS1L TRIM24 ATXN1L TAF1L	3.61e-06	185	70	7	int:LHX3
Interaction	HTR2C interactions	NT5C3A TRMT11 ECPAS ATP2B2 SNTA1 XPO7	6.00e-06	130	70	6	int:HTR2C
Interaction	TLX3 interactions	TET2 PBRM1 CSNK2A2 PAXIP1 BRMS1L TRIM24 ATXN1L SNTA1	7.46e-06	291	70	8	int:TLX3
Interaction	LHX4 interactions	PBRM1 PAXIP1 TRMT11 HMGB1 TRIM24 TAF1L	2.42e-05	166	70	6	int:LHX4
Interaction	KLF5 interactions	TET2 PBRM1 EPC1 PAXIP1 TRIM24 ATXN1L	5.96e-05	195	70	6	int:KLF5
Interaction	GATA2 interactions	EYA4 PBRM1 PAXIP1 BRMS1L TRIM24 ATXN1L	6.67e-05	199	70	6	int:GATA2
Interaction	DPY30 interactions	CSNK2A2 PAXIP1 TSPY3 TSPY10 TSPY2 BRMS1L	7.65e-05	204	70	6	int:DPY30
Interaction	ELF1 interactions	PBRM1 EPC1 BRMS1L TRIM24 ATXN1L	7.71e-05	126	70	5	int:ELF1
Interaction	NFIC interactions	TET2 PAXIP1 ELK3 BRMS1L TRIM24 ATXN1L	8.97e-05	210	70	6	int:NFIC
Cytoband	Yp11.2	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	2.13e-10	94	75	7	Yp11.2
Cytoband	Ensembl 112 genes in cytogenetic band chrYp11	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	5.69e-09	150	75	7	chrYp11
GeneFamily	CD molecules\|5'-nucleotidases	NT5E NT5C3A	1.05e-04	7	41	2	1042
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP12 MMP26	1.34e-03	24	41	2	891
GeneFamily	Tudor domain containing	TDRD7 RNF17	3.18e-03	37	41	2	780
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_or_Epithelioid_Leiomyosarcoma-7\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ABCA12 TSPY4 TSPY10 TSPY2 TSPY9 TSPY8	1.60e-08	99	74	6	4f0346fe85ba006d1ab28a61624568522ffe5cb4
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R2 EPHB3 SGMS2 EPS8L2 DUSP14 SNTA1	9.44e-07	197	74	6	ed3a37f532741764060d297a560eeeeec279d9c4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA12 PCDH15 SPAG17 ANO3	1.39e-05	184	74	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA12 PCDH15 SPAG17 ANO3	1.39e-05	184	74	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA12 PCDH15 SPAG17 ANO3	1.39e-05	184	74	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB3 DUT CC2D2A HMGB1 RPL6	1.62e-05	190	74	5	52c59001a079c76249abbaa3141e9e661b83d9a0
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CHL1 TGFB2 TGM1 EYA4 DUSP14	1.70e-05	192	74	5	8899d81306770adda893b5e146df1253971754c5
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CHL1 TGFB2 TGM1 EYA4 DUSP14	1.70e-05	192	74	5	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	GLB1L2 SPAG17 WDR49 ANO3 NSUN7	1.84e-05	195	74	5	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	Mesenchymal_cells-Fibro/Chondro_p.\|World / Lineage and Cell class	EPS8L2 COL12A1 NT5E DUSP14 COLGALT2	1.88e-05	196	74	5	ddc168849e0e97005a111be004463bb72d433853
ToppCell	CV-Moderate\|CV / Virus stimulation, Condition and Cluster	PPP1R2 PTGES2 HMGB1 ELK3 RPL6	1.93e-05	197	74	5	8747a57ded96175a8365f066101ce2af80c8081d
Disease	Ichthyosis Congenita II	TGM1 ABCA12	3.04e-05	4	67	2	C3536797
Disease	Ichthyosis Congenita I	TGM1 ABCA12	3.04e-05	4	67	2	C4551630
Disease	Harlequin Fetus	TGM1 ABCA12	3.04e-05	4	67	2	C0239849
Disease	autosomal recessive congenital ichthyosis 1 (is_implicated_in)	TGM1 ABCA12	3.04e-05	4	67	2	DOID:0060656 (is_implicated_in)
Disease	Collodion Fetus	TGM1 ABCA12	3.04e-05	4	67	2	C3543867
Disease	Congenital ichthyosis	TGM1 ABCA12	5.06e-05	5	67	2	C0020758
Disease	7-methylguanine measurement	AOX1 MMP26	1.41e-04	8	67	2	EFO_0021123
Disease	lifestyle measurement, maximum cigarettes per day measurement	TDRD7 EPC1 SAXO1 MMP26	1.74e-04	122	67	4	EFO_0009264, EFO_0010724
Disease	Glaucoma	TDRD7 TGFB2	1.81e-04	9	67	2	C0017601
Disease	Congenital ichthyosis of skin	TGM1 ABCA12	2.76e-04	11	67	2	cv:C0020758
Disease	Congenital Nonbullous Ichthyosiform Erythroderma	TGM1 ABCA12	2.76e-04	11	67	2	C0079154
Disease	chemokine (C-C motif) ligand 27 measurement	PBRM1 DNAJA1 TAF1L	5.49e-04	70	67	3	EFO_0008082
Disease	Pulmonary Emphysema	TGFB2 MMP12	6.76e-04	17	67	2	C0034067
Disease	Nonsyndromic genetic hearing loss	EYA4 PCDH15 ATP2B2	6.99e-04	76	67	3	cv:C5680182
Disease	red blood cell density measurement	TET2 TGM1 PBRM1 NT5C3A DUSP14 CC2D2A HMGB1 XPO7	8.35e-04	880	67	8	EFO_0007978
Disease	Nonsyndromic Deafness	EPS8L2 EYA4 PCDH15	8.41e-04	81	67	3	C3711374
Disease	Obsessive-compulsive trait	SGMS2 TRMT11	1.04e-03	21	67	2	HP_0008770
Disease	Colorectal Carcinoma	CHL1 TET2 EYA4 ABCA12 SPAG17 WDR49 RPL6	1.06e-03	702	67	7	C0009402
Disease	body fat distribution	TGFB2 UBE4A PBRM1 COLGALT2	1.17e-03	202	67	4	EFO_0004341
Disease	sciatic neuropathy (implicated_via_orthology)	SNW1 HMGB1	1.25e-03	23	67	2	DOID:11446 (implicated_via_orthology)
Disease	waist-hip ratio	TDRD7 TET2 EYA4 PBRM1 CSNK2A2 EPC1 TRMT11 HMGB1 ANO3	1.75e-03	1226	67	9	EFO_0004343
Disease	complement factor H-related protein 2 measurement	CHL1 COL12A1	1.98e-03	29	67	2	EFO_0600055

Protein segments in the cluster

Peptide	Gene	Start	Entry
VDPVLTVEEKYPYMV	NT5C3A	136	Q9H0P0
YPVKEFEVYPELMEK	CYP4Z2P	61	Q8N1L4
YESIYPGEFKMPKQL	EPC1	86	Q9H2F5
YAPYNPVTKAIMEKS	ABCA12	811	Q86UK0
EEPYVMYRKSDKPLY	GRIK1	456	P39086
VKMVQTPYGIVPDVY	DUSP14	171	O95147
PYRYELIDIPMDSKK	C7orf31	201	Q8N865
MVKETTYYDVLGVKP	DNAJA1	1	P31689
PVRSQMPEEKLYKVY	ATP2B2	586	Q01814
YYKMEIVNPITGKPE	ANO3	521	Q9BYT9
KMDPVHYPSLADKYE	AOX1	536	Q06278
YPHDMKPSAVKDSIY	MMP26	111	Q9NRE1
IVEGYYLKEPVPMQD	RASA1	431	P20936
DPKAVMFPTYKYVDI	MMP12	231	P39900
VSAMVPVKSPREYYV	ZFYVE28	176	Q9HCC9
PKVPEEMFREVKYYA	PAXIP1	6	Q6ZW49
KPVPQTLIMAYDYAK	FEM1C	286	Q96JP0
SELPDYYLTIKKPMD	PBRM1	691	Q86U86
YEREMKTYIPPKGET	HMGB1	71	P09429
RVMTPAVYAPYDVKV	CHL1	771	O00533
KDYGLMKIDEPSTPY	PPP1R2P1	61	Q96PQ5
VDQYGMLYKVAVPPA	ATXN1L	76	P0C7T5
IYVKMGYPRLPVEKQ	ECPAS	101	Q5VYK3
KVVEVKPDMFPPYKY	HMGXB3	591	Q12766
IAPGMKVYIDPFTYE	EPHB3	601	P54753
EPRYILVVPMNKEKY	LRGUK	526	Q96M69
AYDYTIPPMEKAVVK	DUT	141	P33316
GYQPTPAMAKYVKIL	EPS8L2	486	Q9H6S3
KDYGLMKIDEPSTPY	PPP1R2	61	P41236
DYPPVFSKRIYKGMV	PCDH15	921	Q96QU1
YAQKYGKDPPMAVTL	EYA4	391	O95677
MPYSEVKPLIDAVYS	CC2D2A	1566	Q9P2K1
YKIVYKPVGSNEPME	COL12A1	2146	Q99715
AKEAMEHPYFYPVVK	CSNK2A2	316	P19784
VYKFVSFPEILKMDP	ELK3	81	P41970
SKMDLEKPNYIVPDY	DYNC1H1	3111	Q14204
KKPVVVSGPYIVYML	BRMS1L	201	Q5PSV4
KPLYTMEVYEDTPVG	CDH12	386	P55289
NKDPAYMPYVKKALE	GLB1L2	206	Q8IW92
PKIYLSMVYKLEGPT	ENGASE	491	Q8NFI3
SQYVSVVPKYPDKMG	COLGALT2	326	Q8IYK4
IMYVEPQYESPKEQK	OR2A25	256	A4D2G3
GPPKDKAVSYTMVYS	NYAP1	451	Q6ZVC0
LYSSLKNYPVEKMVP	TRMT11	86	Q7Z4G4
EVVLEVKYMKDVSPY	SNTA1	161	Q13424
DKMECLPTYKADYLP	SAXO1	131	Q8IYX7
VPDYYKMIVNPVDLE	TAF1L	1556	Q8IZX4
VPEKTGYPDSVYVMA	NSUN7	36	Q8NE18
YPLLKPYESVMKVKA	ADSL	466	P30566
PLEEIITYYPAMKAV	PTGES2	181	Q9H7Z7
DEMKEYYSKNPKITP	TDRD7	496	Q8NHU6
KGTKKYPDYIQIAMP	SGMS2	51	Q8NHU3
MYVPEDLLPVYKEKV	PDXK	126	O00764
VKHYEFYKTVMPPAE	SPAG17	1266	Q6Q759
VPSYDPLKMDEVYKV	NT5E	481	P21589
CYDTYPPLEKKKVDM	RNF17	336	Q9BXT8
EEYYAKEVYKIDMPP	TGFB2	96	P61812
LQYYKRMKPPEEGTE	TSPY9	291	A0A494C1R9
QYYKRMKPPEEGTET	TSPY10	286	P0CW01
QYYKRMKPPEEGTET	TSPY2	286	A6NKD2
TVPDYYKIIKNPMDL	TRIM24	931	O15164
LQYYKRMKPPEEGTE	TSPY4	291	P0CV99
QYYKRMKPPEEGTET	TSPY1	286	Q01534
VVKLRKMPRYYPTED	RPL6	106	Q02878
YATITYNVPEEKMEK	SAGE1	246	Q9NXZ1
PPELMFVYSYEKLSI	TRBV4-1	61	A0A577
DKAHYEREMKTYIPP	SP100	741	P23497
TCMKETQKPYYGEVI	WDR49	591	Q8IV35
YLKVVMALTYEEKPP	VRK3	431	Q8IV63
VIYSKYTDLVPKEVM	SNW1	111	Q13573
QYYKRMKPPEEGTET	TSPY3	286	P0CV98
QYYKRMKPPEEGTET	TSPY8	286	P0CW00
VPYVKATEPHMLETY	XPO7	391	Q9UIA9
VTMPVAYKEYRPHLV	TGM1	646	P22735
MAKVFVEYIQPKDPT	UBE4A	306	Q14139
TLMAPTYKKLAPDAY	TET2	1331	Q6N021