Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	mCRD-mediated mRNA stability complex	PABPC3 PABPC1	8.70e-05	6	51	2	GO:0106002
MousePheno	abnormal neuronal precursor proliferation	MYT1L SF3B4 SMARCC2 TP53BP2	6.95e-05	74	42	4	MP:0004948
MousePheno	decreased neocortex size	CEP135 HTT	8.76e-05	5	42	2	MP:0020069
Domain	DUF3496	ANKRD26 CCDC144A	2.28e-05	3	52	2	IPR021885
Domain	DUF3496	ANKRD26 CCDC144A	2.28e-05	3	52	2	PF12001
Domain	PolyA	PABPC3 PABPC1	7.56e-05	5	52	2	SM00517
Domain	-	PABPC3 PABPC1	7.56e-05	5	52	2	1.10.1900.10
Domain	PABP	PABPC3 PABPC1	7.56e-05	5	52	2	PF00658
Domain	PABC	PABPC3 PABPC1	7.56e-05	5	52	2	PS51309
Domain	PABP_1234	PABPC3 PABPC1	7.56e-05	5	52	2	IPR006515
Domain	PABP_HYD	PABPC3 PABPC1	7.56e-05	5	52	2	IPR002004
Domain	RRM_dom_euk	PABPC3 PABPC1	1.85e-03	23	52	2	IPR003954
Domain	RRM_1	PABPC3 PABPC1	1.85e-03	23	52	2	SM00361
Domain	RRM_1	SF3B4 PABPC3 PABPC1 HNRNPR	2.66e-03	208	52	4	PF00076
Domain	RRM	SF3B4 PABPC3 PABPC1 HNRNPR	3.10e-03	217	52	4	SM00360
Domain	RRM_dom	SF3B4 PABPC3 PABPC1 HNRNPR	3.64e-03	227	52	4	IPR000504
Domain	RRM	SF3B4 PABPC3 PABPC1 HNRNPR	3.82e-03	230	52	4	PS50102
Domain	-	SF3B4 PABPC3 PABPC1 HNRNPR	4.71e-03	244	52	4	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	SF3B4 PABPC3 PABPC1 HNRNPR	5.73e-03	258	52	4	IPR012677
Domain	Kinesin_motor_CS	STARD9 KIF2C	5.82e-03	41	52	2	IPR019821
Domain	KINESIN_MOTOR_1	STARD9 KIF2C	6.67e-03	44	52	2	PS00411
Domain	-	STARD9 KIF2C	6.67e-03	44	52	2	3.40.850.10
Domain	Kinesin_motor_dom	STARD9 KIF2C	6.67e-03	44	52	2	IPR001752
Domain	Kinesin	STARD9 KIF2C	6.67e-03	44	52	2	PF00225
Domain	KINESIN_MOTOR_2	STARD9 KIF2C	6.67e-03	44	52	2	PS50067
Domain	KISc	STARD9 KIF2C	6.67e-03	44	52	2	SM00129
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	EHBP1 DPYSL3 UAP1 SF3B4 HIVEP1 EXPH5 STARD9 ANKRD26 EPB41L5 PABPC1 PLK4 GOLGA4 TP53BP2 NSD3 FAM83B KIF2C	1.10e-13	861	53	16	36931259
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	BPTF SF3B4 HIVEP1 DEAF1 MBNL2 PABPC3 CAST SMARCC2 TAF4 PABPC1 MTDH NSD3 HNRNPR	1.40e-09	954	53	13	36373674
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	EHBP1 EXPH5 ANKRD26 EPB41L5 MTDH TP53BP2 FAM83B	1.50e-07	263	53	7	34702444
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	XIRP2 EXPH5 DOCK9 TAF4 GALNT5 F2 RIC1 KIF2C	8.29e-07	497	53	8	36774506
Pubmed	The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.	SF3B4 PABPC3 PABPC1	9.45e-07	13	53	3	17218272
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	EHBP1 STXBP6 EXPH5 DOCK9 ANKRD26 EPB41L5 JPH2 FAM83B	2.27e-06	569	53	8	30639242
Pubmed	Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.	PABPC3 PABPC1	2.28e-06	2	53	2	19020299
Pubmed	Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.	PABPC3 PABPC1	2.28e-06	2	53	2	26971890
Pubmed	Thrombin Cleavage of Inter-α-inhibitor Heavy Chain 1 Regulates Leukocyte Binding to an Inflammatory Hyaluronan Matrix.	F2 ITIH1	2.28e-06	2	53	2	27679489
Pubmed	Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.	PABPC3 PABPC1	2.28e-06	2	53	2	10954604
Pubmed	The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.	PABPC3 PABPC1	2.28e-06	2	53	2	10534404
Pubmed	Calpastatin ablation aggravates the molecular phenotype in cell and animal models of Huntington disease.	CAST HTT	2.28e-06	2	53	2	29355642
Pubmed	The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: intimations that gene expression in spermatogenic cells facilitates the creation of new genes.	PABPC3 PABPC1	2.28e-06	2	53	2	9732454
Pubmed	Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.	PABPC3 PABPC1	2.28e-06	2	53	2	1630930
Pubmed	Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.	PABPC3 PABPC1	2.28e-06	2	53	2	7893484
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	DPYSL3 SF3B4 SMARCC2 PABPC1 MTDH TP53BP2 KIF2C HNRNPR	4.02e-06	615	53	8	31048545
Pubmed	A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.	SF3B4 PABPC3 PABPC1	4.36e-06	21	53	3	19345177
Pubmed	Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.	EHBP1 DPYSL3 PABPC3 PABPC1 HNRNPR	5.40e-06	165	53	5	16107646
Pubmed	Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence.	PABPC3 PABPC1	6.83e-06	3	53	2	26134869
Pubmed	Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.	TAF4 HTT	6.83e-06	3	53	2	11988536
Pubmed	Human testis expresses a specific poly(A)-binding protein.	PABPC3 PABPC1	6.83e-06	3	53	2	11328870
Pubmed	Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos.	PABPC3 PABPC1	6.83e-06	3	53	2	25034140
Pubmed	Epab is dispensable for mouse spermatogenesis and male fertility.	PABPC3 PABPC1	6.83e-06	3	53	2	24599567
Pubmed	Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types.	PABPC3 PABPC1	6.83e-06	3	53	2	29578408
Pubmed	SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport.	PABPC3 PABPC1	6.83e-06	3	53	2	28756945
Pubmed	The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.	PABPC3 PABPC1	6.83e-06	3	53	2	26843391
Pubmed	Domain-functional analyses of PIWIL1 and PABPC1 indicate their synergistic roles in protein translation via 3'-UTRs of meiotic mRNAs.	PABPC3 PABPC1	6.83e-06	3	53	2	29701755
Pubmed	Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.	PABPC3 PABPC1	6.83e-06	3	53	2	21940797
Pubmed	Translation repression via modulation of the cytoplasmic poly(A)-binding protein in the inflammatory response.	PABPC3 PABPC1	6.83e-06	3	53	2	28635594
Pubmed	The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs.	PABPC3 PABPC1	6.83e-06	3	53	2	10076007
Pubmed	Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries.	PABPC3 PABPC1	6.83e-06	3	53	2	25370180
Pubmed	Epab and Pabpc1 are differentially expressed during male germ cell development.	PABPC3 PABPC1	6.83e-06	3	53	2	22814100
Pubmed	Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells.	PABPC3 PABPC1	6.83e-06	3	53	2	28611064
Pubmed	A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway.	PABPC3 PABPC1	6.83e-06	3	53	2	37665675
Pubmed	De novo variants in the PABP domain of PABPC1 lead to developmental delay.	PABPC3 PABPC1	6.83e-06	3	53	2	35511136
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	BPTF PABPC3 CAST ASPM EPB41L5 GOLGA4 TP53BP2	7.29e-06	472	53	7	38943005
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	SF3B4 MBNL2 PABPC3 SMARCC2 PABPC1 GOLGA4 KIF2C HNRNPR	1.30e-05	723	53	8	34133714
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	SF3B4 MBNL2 CAST ANKRD26 EPB41L5 PABPC1 MTDH HNRNPR	1.32e-05	724	53	8	36232890
Pubmed	Regulation of poly(A) binding protein function in translation: Characterization of the Paip2 homolog, Paip2B.	PABPC3 PABPC1	1.36e-05	4	53	2	16804161
Pubmed	Evolution of complexity in the zebrafish synapse proteome.	PABPC3 PABPC1	1.36e-05	4	53	2	28252024
Pubmed	Centriole signaling restricts hepatocyte ploidy to maintain liver integrity.	ANKRD26 PLK4	1.36e-05	4	53	2	35981754
Pubmed	Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.	CEP135 PLK4	1.36e-05	4	53	2	24997597
Pubmed	An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.	PABPC3 PABPC1	1.36e-05	4	53	2	15630085
Pubmed	Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP.	PABPC3 PABPC1	1.36e-05	4	53	2	18490513
Pubmed	UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant.	PABPC3 PABPC1	1.36e-05	4	53	2	15314026
Pubmed	Stress granules inhibit apoptosis by reducing reactive oxygen species production.	PABPC3 PABPC1	1.36e-05	4	53	2	23230274
Pubmed	Transthyretin Upregulates Long Non-Coding RNA MEG3 by Affecting PABPC1 in Diabetic Retinopathy.	PABPC3 PABPC1	1.36e-05	4	53	2	31847264
Pubmed	RNA-binding proteins in mouse oocytes and embryos: expression of genes encoding Y box, DEAD box RNA helicase, and polyA binding proteins.	PABPC3 PABPC1	1.36e-05	4	53	2	9883581
Pubmed	Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.	PABPC3 PABPC1	1.36e-05	4	53	2	24129315
Pubmed	cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation.	PABPC3 PABPC1	1.36e-05	4	53	2	28910620
Pubmed	ATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice.	PABPC3 PABPC1	1.36e-05	4	53	2	22956915
Pubmed	Functional cloning of genes that suppress oxidative stress-induced cell death: TCTP prevents hydrogen peroxide-induced cell death.	PABPC3 PABPC1	1.36e-05	4	53	2	19328788
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	BPTF DPYSL3 CAST TAF4 TP53BP2 HTT NSD3	1.93e-05	549	53	7	38280479
Pubmed	Plk4-induced centriole biogenesis in human cells.	CEP135 PLK4	2.27e-05	5	53	2	17681131
Pubmed	HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.	PABPC3 PABPC1	2.27e-05	5	53	2	19956697
Pubmed	NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.	BPTF NSD3	2.27e-05	5	53	2	26626481
Pubmed	Interaction of HuDA and PABP at 5'UTR of mouse insulin2 regulates insulin biosynthesis.	PABPC3 PABPC1	2.27e-05	5	53	2	29590218
Pubmed	Poly(A) tail length regulates PABPC1 expression to tune translation in the heart.	PABPC3 PABPC1	2.27e-05	5	53	2	28653618
Pubmed	Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.	PABPC3 PABPC1	2.27e-05	5	53	2	26492470
Pubmed	Isolation of cDNAs from a mouse astroglial cell line by a subtracted cDNA library.	PABPC3 PABPC1	2.27e-05	5	53	2	1701491
Pubmed	AKAP3 synthesis is mediated by RNA binding proteins and PKA signaling during mouse spermiogenesis.	PABPC3 PABPC1	2.27e-05	5	53	2	24648398
Pubmed	MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.	PABPC3 PABPC1	2.27e-05	5	53	2	33744966
Pubmed	Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells.	PABPC3 PABPC1	3.40e-05	6	53	2	17927953
Pubmed	Translation of insulin granule proteins are regulated by PDI and PABP.	PABPC3 PABPC1	3.40e-05	6	53	2	32248978
Pubmed	The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.	PABPC3 PABPC1	3.40e-05	6	53	2	10358005
Pubmed	Embryonic poly(A)-binding protein is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos.	PABPC3 PABPC1	3.40e-05	6	53	2	30302808
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BPTF HIVEP1 DEAF1 SMARCC2 TAF4 NSD3 SENP7	3.70e-05	608	53	7	36089195
Pubmed	E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.	PABPC3 PABPC1	4.76e-05	7	53	2	34143182
Pubmed	Genetic imbalances in preleukemic thymuses.	PABPC3 PABPC1	4.76e-05	7	53	2	11322760
Pubmed	Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.	PABPC3 PABPC1	4.76e-05	7	53	2	10543404
Pubmed	NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.	PABPC3 PABPC1	4.76e-05	7	53	2	34784943
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	BPTF STARD9 PABPC3 ASPM ANKRD26 SMARCC2 TAF4 PABPC1 MTDH HNRNPR	5.57e-05	1442	53	10	35575683
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	ERCC8 SF3B4 CEP135 ASPM SMARCC2 PABPC1 PLK4 FAM83B HNRNPR	5.67e-05	1155	53	9	20360068
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	SF3B4 SMARCC2 PABPC1 MTDH HNRNPR	6.16e-05	274	53	5	34244482
Pubmed	Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse.	PABPC3 PABPC1	6.34e-05	8	53	2	21262862
Pubmed	Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription.	TAF4 HTT	6.34e-05	8	53	2	30994454
Pubmed	Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.	PABPC3 PABPC1	6.34e-05	8	53	2	22621333
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	EHBP1 BPTF MBNL2 CAST TRMT13 TAF4 SMOC2 GOLGA4 RIC1 HTT	7.28e-05	1489	53	10	28611215
Pubmed	RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis.	PABPC3 PABPC1	8.15e-05	9	53	2	36001654
Pubmed	Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte-somatic communication.	PABPC3 PABPC1	8.15e-05	9	53	2	28203794
Pubmed	Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase.	PABPC3 PABPC1	8.15e-05	9	53	2	24396066
Pubmed	Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells.	PABPC3 PABPC1	8.15e-05	9	53	2	18625844
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	BPTF SMARCC2 TAF4 NSD3	8.26e-05	150	53	4	28242625
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	SF3B4 EPB41L5 SMARCC2 PABPC1 MTDH HNRNPR	9.50e-05	486	53	6	30940648
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EHBP1 ANKRD26 EPB41L5 PABPC1 GOLGA4 FAM83B KIF2C	9.61e-05	708	53	7	39231216
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PABPC3 SMARCC2 TAF4 PABPC1 ITIH1 GOLGA4 TP53BP2 KIF2C	9.86e-05	963	53	8	28671696
Pubmed	The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator.	PABPC3 PABPC1	1.02e-04	10	53	2	21984414
Pubmed	Granzyme B proteolyzes receptors important to proliferation and survival, tipping the balance toward apoptosis.	PABPC3 PABPC1	1.02e-04	10	53	2	16798735
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EHBP1 EXPH5 CEP135 ANKRD26 EPB41L5 RIC1	1.03e-04	493	53	6	15368895
Pubmed	Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.	DPYSL3 PABPC3 PABPC1 HNRNPR	1.22e-04	166	53	4	27160897
Pubmed	Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1.	DOCK9 EPB41L5 PABPC1	1.37e-04	65	53	3	18729074
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	SF3B4 CAST SMARCC2 TP53BP2 HNRNPR	1.45e-04	329	53	5	17474147
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	BPTF UAP1 SMARCC2 TAF4 NSD3 KIF2C	1.57e-04	533	53	6	30554943
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	HDX TAF4 PABPC1 MTDH KIF2C HNRNPR	1.88e-04	551	53	6	34728620
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	UAP1 STXBP6 ASPM HTT	1.89e-04	186	53	4	33637726
Pubmed	Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.	PABPC3 PABPC1	2.05e-04	14	53	2	19716330
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	EHBP1 STXBP6 DOCK9 CAST TP53BP2 FAM83B	2.15e-04	565	53	6	25468996
Pubmed	Uncovering a mammalian neural-specific poly(A) binding protein with unique properties.	PABPC3 PABPC1	2.36e-04	15	53	2	37704377
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	BPTF HIVEP1 DEAF1 SMARCC2 TAF4 PABPC1 KIF2C HNRNPR	2.49e-04	1103	53	8	34189442
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	HIVEP1 ASPM ANKRD26 FAM83B KIF2C HNRNPR	2.66e-04	588	53	6	38580884
Interaction	YWHAH interactions	EHBP1 DPYSL3 UAP1 HIVEP1 EXPH5 STARD9 DOCK9 CEP135 ANKRD26 EPB41L5 PLK4 GOLGA4 TP53BP2 HTT NSD3 FAM83B KIF2C	1.10e-09	1102	52	17	int:YWHAH
Interaction	YWHAG interactions	EHBP1 DPYSL3 UAP1 SF3B4 HIVEP1 EXPH5 STARD9 DOCK9 ANKRD26 EPB41L5 PABPC1 PLK4 TP53BP2 HTT FAM83B KIF2C	5.27e-08	1248	52	16	int:YWHAG
Interaction	SMC5 interactions	BPTF SF3B4 HIVEP1 DEAF1 MBNL2 PABPC3 CAST SMARCC2 TAF4 PABPC1 MTDH NSD3 HNRNPR	1.07e-06	1000	52	13	int:SMC5
Interaction	YWHAB interactions	UAP1 SF3B4 HIVEP1 EXPH5 STARD9 DOCK9 ANKRD26 EPB41L5 PLK4 TP53BP2 HTT FAM83B	7.87e-06	1014	52	12	int:YWHAB
Interaction	RNF43 interactions	EHBP1 EXPH5 CEP135 ANKRD26 EPB41L5 MTDH TP53BP2 FAM83B	1.27e-05	427	52	8	int:RNF43
Interaction	STX4 interactions	EHBP1 STXBP6 ANKRD26 EPB41L5 MTDH GOLGA4 TP53BP2 FAM83B	1.29e-05	428	52	8	int:STX4
Interaction	SRGAP3 interactions	SMARCC2 TP53BP2 HTT KIF2C	1.61e-05	59	52	4	int:SRGAP3
Interaction	STX6 interactions	EHBP1 STXBP6 ANKRD26 EPB41L5 GOLGA4 RIC1 HTT FAM83B	1.79e-05	448	52	8	int:STX6
Interaction	ZFPL1 interactions	EHBP1 ANKRD26 EPB41L5 HDAC10 GOLGA4 RIC1 TSPAN1 FAM83B	1.79e-05	448	52	8	int:ZFPL1
Interaction	SFN interactions	UAP1 EXPH5 ANKRD26 EPB41L5 PABPC1 PLK4 TP53BP2 HTT FAM83B	6.17e-05	692	52	9	int:SFN
Interaction	YWHAE interactions	UAP1 HIVEP1 EXPH5 DOCK9 HDX ANKRD26 SMARCC2 TAF4 PLK4 TP53BP2 HTT FAM83B	6.55e-05	1256	52	12	int:YWHAE
Interaction	FBXO22 interactions	XIRP2 EXPH5 DOCK9 TAF4 GALNT5 F2 RIC1 KIF2C	6.73e-05	540	52	8	int:FBXO22
Interaction	EBAG9 interactions	EHBP1 ANKRD26 EPB41L5 GOLGA4 RIC1 FAM83B	1.25e-04	303	52	6	int:EBAG9
Interaction	RIDA interactions	SF3B4 HIVEP1 DEAF1	1.28e-04	38	52	3	int:RIDA
Interaction	H2BC9 interactions	BPTF HIVEP1 XIRP2 JPH2 SMARCC2 TAF4 TP53BP2	1.40e-04	446	52	7	int:H2BC9
Interaction	GJD3 interactions	EHBP1 ANKRD26 EPB41L5 MTDH GOLGA4 RIC1 FAM83B	1.57e-04	454	52	7	int:GJD3
Interaction	HOXC4 interactions	RNF32 HTT NSD3	1.73e-04	42	52	3	int:HOXC4
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	FAP XIRP2 GALNT5	4.38e-04	127	53	3	chr2q24
Cytoband	1p34.1	TSPAN1 KIF2C	2.00e-03	57	53	2	1p34.1
Cytoband	4p16.3	ZBTB49 HTT	4.39e-03	85	53	2	4p16.3
Cytoband	Ensembl 112 genes in cytogenetic band chr13q32	MBNL2 DOCK9	5.56e-03	96	53	2	chr13q32
GeneFamily	RNA binding motif containing	SF3B4 PABPC3 PABPC1 HNRNPR	5.86e-04	213	33	4	725
GeneFamily	Kinesins\|Pleckstrin homology domain containing	STARD9 KIF2C	3.18e-03	46	33	2	622
GeneFamily	PHD finger proteins	BPTF NSD3	1.17e-02	90	33	2	88
Coexpression	TABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING	BPTF SF3B4 STXBP6 PABPC3 EFCAB14 PABPC1 MTDH NSD3 HNRNPR	8.56e-06	685	53	9	MM3782
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	EHBP1 BPTF HIVEP1 CEP135 TAF4 GOLGA4 TP53BP2	4.08e-05	466	53	7	M13522
Coexpression	PAL_PRMT5_TARGETS_DN	MYT1L PABPC3 PABPC1	4.88e-05	35	53	3	MM674
Coexpression	JOHNSTONE_PARVB_TARGETS_3_DN	UAP1 CAST ASPM CAPS2 PLK4 NSD3 SENP7 KIF2C HNRNPR	5.96e-05	877	53	9	M2241
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_DN	FAP CAST	8.37e-05	7	53	2	M1357
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX2_DN	FAP CAST	8.37e-05	7	53	2	MM568
Coexpression	ZHAN_MULTIPLE_MYELOMA_MF_DN	STXBP6 DOCK9 MTDH	9.10e-05	43	53	3	M513
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	FAP DPYSL3 MBNL2 STARD9 ASPM CAPS2 SMOC2 HTT NSD3 SENP7 HNRNPR	2.94e-06	799	52	11	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	FAP DPYSL3 STARD9 ASPM GALNT5 CAPS2 SMOC2 HTT NSD3 SENP7 HNRNPR	3.02e-06	801	52	11	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	FAP DPYSL3 STARD9 ASPM GALNT5 CAPS2 SENP7 HNRNPR	6.81e-06	413	52	8	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	FAP STXBP6 CEP135 ASPM ANKRD26 SMARCC2 EFCAB14 PLK4 RIC1 NSD3 SENP7 KIF2C	3.83e-05	1252	52	12	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000	FAP STARD9 ASPM HTT NSD3 SENP7	6.22e-05	281	52	6	gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	FAP DPYSL3 STARD9 ASPM CAPS2 SMOC2 HTT NSD3 HNRNPR	1.14e-04	790	52	9	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	MYT1L DPYSL3 CCDC73 ASPM CAPS2 HTT NSD3 SENP7 HNRNPR	1.20e-04	795	52	9	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#5	CCDC73 GALNT5 TSPAN1 FAM83B	2.34e-04	123	52	4	Arv_EB-LF_1000_K5
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_200	MYT1L CCDC73 CAPS2	2.36e-04	49	52	3	gudmap_developingGonad_e18.5_ovary_200_k1
ToppCell	normal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ\|normal_Lymph_Node / Location, Cell class and cell subclass	STXBP6 ASPM PLK4 CCDC144A KIF2C	3.35e-06	193	53	5	5ce93860bc60ce6ecfed3a3d985f84e28781eec1
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ERCC8 ASPM KIF2C HNRNPR	1.45e-05	124	53	4	1483be8700eca7e2c288784a290d945d4022b17f
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ASPM F2 FAM83B KIF2C	1.85e-05	132	53	4	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7\|TCGA-Brain / Sample_Type by Project: Shred V9	ASPM PLK4 FAM83B HNRNPR	2.08e-05	136	53	4	d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	UBQLNL DPYSL3 GALNT5 TSPAN1	3.75e-05	158	53	4	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAP DPYSL3 DOCK9 SMOC2	4.87e-05	169	53	4	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ASPM PABPC1 PLK4 KIF2C	4.99e-05	170	53	4	b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCell	Club-club-15\|World / Class top	ASPM F2 PLK4 KIF2C	5.58e-05	175	53	4	ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCell	ASK440-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	EHBP1 ZBTB49 ASPM TAF4	5.96e-05	178	53	4	86f1741636ed3e85bb4a65f84949b718fc38c290
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	DOCK9 JPH2 TAF4 HNRNPR	6.09e-05	179	53	4	83506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ASPM PABPC1 KIF2C HNRNPR	6.23e-05	180	53	4	44988c34861df359a68376500c42a64fbcc4b431
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYT1L EXPH5 EPB41L5 TP53BP2	6.50e-05	182	53	4	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYT1L EXPH5 EPB41L5 TP53BP2	6.50e-05	182	53	4	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 UAP1 SMOC2	7.07e-05	186	53	4	a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCell	IPF-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	ASPM CCDC144CP PLK4 CCDC144A	7.07e-05	186	53	4	f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBNL2 MTDH GOLGA4 NSD3	7.22e-05	187	53	4	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAP ASPM PLK4 KIF2C	7.22e-05	187	53	4	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAP ASPM PLK4 KIF2C	7.22e-05	187	53	4	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 ASPM PLK4 KIF2C	7.22e-05	187	53	4	4d12c70c8ed922fbc8f7b139145611203735cab4
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 ASPM PLK4 KIF2C	7.22e-05	187	53	4	e851ee46a6b4068a7bd7602ee183c0ace50ee4dd
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 ASPM PLK4 KIF2C	7.22e-05	187	53	4	e46b49b4053d2d0f3e1d2bcdc380f7f8733cbe07
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 UAP1 SMOC2	7.37e-05	188	53	4	2cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BPTF DPYSL3 MBNL2 PABPC1	7.37e-05	188	53	4	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 UAP1 SMOC2	7.52e-05	189	53	4	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD9 DOCK9 ASPM KIF2C	7.68e-05	190	53	4	31de1727822e9818652946dfb962daee77ffad68
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 UAP1 SMOC2	7.68e-05	190	53	4	ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPYSL3 STXBP6 STARD9 DOCK9	7.68e-05	190	53	4	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DPYSL3 STXBP6 STARD9 DOCK9	7.83e-05	191	53	4	f229abf69a1217194f74b0502486907e07dba989
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CEP135 ASPM PLK4 KIF2C	7.83e-05	191	53	4	0ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAP DPYSL3 STARD9 JPH2	7.83e-05	191	53	4	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3\|TCGA-Ovary / Sample_Type by Project: Shred V9	FAP DPYSL3 GALNT5 MTDH	7.83e-05	191	53	4	80d30d8eedb4c70b58440646325bc04c5700803e
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAP DPYSL3 GALNT5 SMOC2	7.99e-05	192	53	4	41a8326cd5bc19ad5041068501bab4c72399222e
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	EHBP1 BPTF HIVEP1 GOLGA4	7.99e-05	192	53	4	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAP DPYSL3 GALNT5 SMOC2	7.99e-05	192	53	4	f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	BPTF ASPM PABPC1 KIF2C	7.99e-05	192	53	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 UAP1 SMOC2	7.99e-05	192	53	4	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 HDX SMOC2	8.15e-05	193	53	4	03678162648bd5b1d65a5450b60c8863edbf95c7
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 HDX SMOC2	8.15e-05	193	53	4	59b8186d0221fba06a16157e9d148399ed801f38
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Control / Condition, Lineage and Cell class	STXBP6 ASPM PLK4 KIF2C	8.15e-05	193	53	4	33d409d6ed1c606337248587ad997ac5f67f081d
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	EHBP1 BPTF HIVEP1 GOLGA4	8.15e-05	193	53	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 UAP1 SMOC2	8.15e-05	193	53	4	160691b671710be10220803d788c2c961c236af1
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAP DPYSL3 HDX SMOC2	8.15e-05	193	53	4	dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAP DPYSL3 JPH2 SMOC2	8.32e-05	194	53	4	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	CCDC73 ASPM PLK4 KIF2C	8.49e-05	195	53	4	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAP DPYSL3 GALNT5 SMOC2	8.49e-05	195	53	4	47762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCell	tumor_Lung-B_lymphocytes-GC_B_cells_in_the_DZ\|B_lymphocytes / Location, Cell class and cell subclass	ASPM PLK4 CCDC144A KIF2C	8.49e-05	195	53	4	339e81a3a5b1f71c0d15ef1ef0f6999378704923
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAP ASPM PLK4 KIF2C	8.65e-05	196	53	4	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	FAP ASPM PLK4 KIF2C	8.65e-05	196	53	4	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ASPM GALNT5 FAM83B KIF2C	8.83e-05	197	53	4	fb272c9c60ee3d980e528044dc567b4925a23da6
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ASPM PLK4 FAM83B KIF2C	8.83e-05	197	53	4	25bbe270d0897b9b1bd00d205f66efd1def81b99
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	HIVEP1 GALNT5 TSPAN1 FAM83B	8.83e-05	197	53	4	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ASPM GALNT5 FAM83B KIF2C	8.83e-05	197	53	4	61c0d78b29dc4ad8a84172cbfcdab03f31351d0e
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ASPM GALNT5 FAM83B KIF2C	8.83e-05	197	53	4	dcabea5c50c133c9a4e294e447462d0393174ea7
ToppCell	moderate-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	UAP1 GALNT5 MTDH GOLGA4	9.00e-05	198	53	4	7ecce5e266bb08797088cc8f8309e0c7b48df5c9
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	EXPH5 EPB41L5 GALNT5 TP53BP2	9.00e-05	198	53	4	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	BPTF EXPH5 ANKRD26 GOLGA4	9.00e-05	198	53	4	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CEP135 ASPM PLK4 KIF2C	9.00e-05	198	53	4	5f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ASPM GALNT5 FAM83B KIF2C	9.00e-05	198	53	4	e06d41a7254a09e037ec404be2d8c352d5cbd7f4
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	EXPH5 EPB41L5 GALNT5 TP53BP2	9.00e-05	198	53	4	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	STXBP6 ASPM PLK4 KIF2C	9.00e-05	198	53	4	dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CEP135 ASPM PLK4 KIF2C	9.00e-05	198	53	4	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	UAP1 ASPM PLK4 KIF2C	9.00e-05	198	53	4	2d8d4eb21b4fe3cc178b3518b3ea39c2d9650f24
ToppCell	normal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ\|B_lymphocytes / Location, Cell class and cell subclass	ASPM PLK4 CCDC144A KIF2C	9.00e-05	198	53	4	41e4bc7964a4895dd05bc62f0ef632ce9c89e34f
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	BPTF CAST ANKRD26 GOLGA4	9.18e-05	199	53	4	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CEP135 ASPM PLK4 KIF2C	9.18e-05	199	53	4	d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCell	severe-Lymphocytic-Prol._cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ASPM PLK4 KIF2C HNRNPR	9.18e-05	199	53	4	b24315952b6ac6c8d2d3a7bd949a5b5392624d4e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CEP135 ASPM PLK4 KIF2C	9.18e-05	199	53	4	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	STXBP6 ASPM PLK4 KIF2C	9.18e-05	199	53	4	2fbf94f7858250088e0f5ce1ff51892730a13ae8
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	BPTF ANKRD26 GOLGA4 NSD3	9.18e-05	199	53	4	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells-Neuroepithelial_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	STXBP6 ASPM PLK4 KIF2C	9.36e-05	200	53	4	2938a029fa0478be561574ace91f95c4a528b2d4
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	CEP135 ASPM PLK4 KIF2C	9.36e-05	200	53	4	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	NS-control-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EXPH5 CAST GALNT5 TSPAN1	9.36e-05	200	53	4	d014959891893b6d3854a471fba1dc50c6625a0a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	CEP135 ASPM PLK4 KIF2C	9.36e-05	200	53	4	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Proliferating\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	STXBP6 ASPM PLK4 KIF2C	9.36e-05	200	53	4	9279415f5e76cb5b4e071c6582ac249b72dd694c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells\|3m / Sample Type, Dataset, Time_group, and Cell type.	STXBP6 ASPM PLK4 KIF2C	9.36e-05	200	53	4	cfe017b4a4d604a553d0a3df9659687f38e9a7af
ToppCell	Severe-Developping_Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	UAP1 ASPM PLK4 KIF2C	9.36e-05	200	53	4	80639e0d2ddaae36ac7634a4f03e8809af7316e3
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Proliferating-Cycling\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	STXBP6 ASPM PLK4 KIF2C	9.36e-05	200	53	4	d582385b2dbb25eeba1b22c5d258a8f26a40ef8b
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	EXPH5 GALNT5 SMOC2	4.64e-04	127	53	3	9bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCell	Control-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYT1L RNF32 SMOC2	4.64e-04	127	53	3	556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Nos1_(CA3_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	EXPH5 GALNT5 SMOC2	4.75e-04	128	53	3	9128b633879d21de2ebe651384cfec6d2c3c2932
ToppCell	LPS-antiTNF-Unknown-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ASPM F2 KIF2C	4.97e-04	130	53	3	615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCell	(08)_PNEC-(2)_48hpi\|(08)_PNEC / shred by cell type and Timepoint	HDX CAST RIC1	6.42e-04	142	53	3	e95d34170f5053678e0dd9793e68d93c03b05822
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC8 HDAC10 PLK4	6.42e-04	142	53	3	a88bf4bcc80206b16dcc504cc19a3380d01e34a4
ToppCell	Control-B_intermediate-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PABPC3 PABPC1 NSD3	6.69e-04	144	53	3	984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZBTB49 CEP135 PLK4	7.39e-04	149	53	3	65778f19599b4955c0a16f0121237656449431fb
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN4_thymocyte\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ASPM PLK4 KIF2C	7.39e-04	149	53	3	89faa84af68d4727180f39718964bb3bc65d8fe6
ToppCell	normal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	TRMT13 RIC1 KIF2C	7.39e-04	149	53	3	a34d095b8e0fe59d69d84e4fd2fe4ccb82f92e4f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	XIRP2 PABPC3 CCDC144A	7.53e-04	150	53	3	6c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ASPM SMOC2 KIF2C	7.68e-04	151	53	3	c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCell	Dividing_Macrophages-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ASPM PLK4 KIF2C	7.82e-04	152	53	3	e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	EXPH5 SMARCC2 HNRNPR	7.97e-04	153	53	3	88ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	EXPH5 SMARCC2 HNRNPR	7.97e-04	153	53	3	553dff9688a1996d8f4ba16e60c683593d781389
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EXPH5 TRMT13 FAM83B	8.28e-04	155	53	3	5fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PABPC3 PABPC1 NSD3	8.28e-04	155	53	3	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6\|TCGA-Kidney / Sample_Type by Project: Shred V9	ASPM PLK4 KIF2C	8.43e-04	156	53	3	d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	PLK4 TP53BP2 KIF2C	8.43e-04	156	53	3	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CCDC73 ANKRD26 PLK4	8.59e-04	157	53	3	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	XIRP2 PLK4 TSPAN1	8.91e-04	159	53	3	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAP SMOC2 PLK4	8.91e-04	159	53	3	7ed659163f45e0c4df4782997c0786900c8186c8
ToppCell	normal_Lung-Myeloid_cells-Undetermined\|Myeloid_cells / Location, Cell class and cell subclass	DEAF1 EXPH5 DOCK9	9.24e-04	161	53	3	283012858e575c70d09950de53da041509f59bfa
Computational	Neighborhood of HBP1	SF3B4 MTDH SENP7 HNRNPR	1.14e-04	70	39	4	GCM_HBP1
Drug	Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A	ERCC8 DEAF1 EXPH5 ANKRD26 SMARCC2 TRMT13	6.00e-06	195	53	6	7225_DN
Disease	Primary microcephaly	CEP135 ASPM PLK4	7.76e-06	22	52	3	C0431350
Disease	loneliness measurement	BPTF DPYSL3 HIVEP1 SMOC2	6.88e-05	124	52	4	EFO_0007865
Disease	Intellectual Disability	MYT1L BPTF DEAF1 SMARCC2 HTT HNRNPR	1.32e-04	447	52	6	C3714756
Disease	Autosomal recessive primary microcephaly	CEP135 ASPM	3.15e-04	15	52	2	cv:C3711387
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	BPTF HIVEP1 CAST HTT SENP7	4.49e-04	364	52	5	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	Autosomal Recessive Primary Microcephaly	CEP135 ASPM	6.88e-04	22	52	2	C3711387
Disease	body fat percentage	BPTF HIVEP1 CAST HTT SENP7	1.66e-03	488	52	5	EFO_0007800

Protein segments in the cluster

Peptide	Gene	Start	Entry
SQRNAENTKSNVTHK	CAPS2	151	Q9BXY5
AVKIVSAKNHQSAAE	DPYSL3	416	Q14195
QFHSAAKNLQAESEK	CCDC144CP	886	Q8IYA2
HKAASAGNVAKVQQI	ANKRD26	51	Q9UPS8
KSQQVAAAAHEANKL	BPTF	791	Q12830
SAVNHLKANVKSAAD	EFCAB14	166	O75071
VHSANVSKVSFNEKA	ASPM	261	Q8IZT6
KNFQQAVQSALTKTH	TP53BP2	621	Q13625
TSNLDNAFAHVTKAQ	RIC1	571	Q4ADV7
AHQAKEAAQKAVNSA	PABPC1	616	P11940
TSHAKAKAEAAEQAA	JPH2	391	Q9BR39
SVLNAGNSVFNHAKK	HDX	181	Q7Z353
ADNKQSSFKADVQAH	ITIH1	516	P19827
KQKSAHVNSLAQDET	GOLGA4	1116	Q13439
KNVQKVAQSTAHGTD	FAM83B	66	Q5T0W9
QQFKESDLSHVQNKS	HNRNPR	81	O43390
SKHENSKDVTAAQNL	EXPH5	1711	Q8NEV8
LDQHNGKKSQAVESA	ERCC8	226	Q13216
GKKSQAVESANTAHN	ERCC8	231	Q13216
AHQAKEATQKAVNSA	PABPC3	611	Q9H361
KVQAQKFSHVAGDSS	CEP135	646	Q66GS9
HKNANVQDAATNSAV	EPB41L5	586	Q9HCM4
TSVTKNRADKNAIHN	HTT	1406	P42858
VFNNVAIAAAHAKQK	HDAC10	146	Q969S8
QKHQSETALKNVFTA	DOCK9	1441	Q9BZ29
AATNQAKIHADAERK	DEAF1	486	O75398
QSKEVNANKHKANTS	GALNT5	261	Q7Z7M9
NENSHASQAKDVKTA	CCDC73	781	Q6ZRK6
DAALKAGNKHNTNTA	EHBP1	831	Q8NDI1
NDAHNKKAVSRSAEQ	CAST	76	P20810
QAKIKAAQHQANQAA	MBNL2	241	Q5VZF2
KNKGDSHLNVQVSNF	MTDH	246	Q86UE4
QFHSAAKNLQAESEK	CCDC144A	1076	A2RUR9
NKAESALAQQAKHFS	KIF2C	681	Q99661
SAVSAQAAAAQKNKL	TAF4	806	O00268
SKTVDDNSAKQTAHN	SENP7	231	Q9BQF6
NGDSATKHLKQQASI	TRMT13	156	Q9NUP7
GHSSKKDNLAVNAVA	RNF32	6	Q9H0A6
QKNACHSNVTTATKA	STARD9	1651	Q9P2P6
KNSDASDNAHSVKQQ	PLK4	526	O00444
KRHQGTVTEDKNNAS	SMARCC2	161	Q8TAQ2
ADDNVHFQNSAQIAK	FAP	701	Q12884
VSNVHVSNNKNSEQK	XIRP2	2881	A4UGR9
KNSAQQFAETAHKLA	STXBP6	191	Q8NFX7
GQAKQAAHECSTSQK	nan	116	Q6ZTK2
NKTNKNSVSSCDQEH	SMOC2	206	Q9H3U7
NDTLNKVNHTSKANT	UBQLNL	346	Q8IYU4
KAIEGFNQSSHQKNV	UAP1	51	Q16222
AEATKQASNHSEKQK	NSD3	341	Q9BZ95
QAKALSKHQDFNSAV	F2	241	P00734
NSSSQKNDVFHLDVK	ZBTB49	56	Q6ZSB9
LQAKHKQNTEESSFA	HIVEP1	71	P15822
VNKASAHNKNLDVGA	SF3B4	86	Q15427
TEKNQTDKAQVHAVS	nan	141	A6NL46
NTANETCTKQKAHDQ	TSPAN1	181	O60635
QEKHQSCDVSKSSQA	MYT1L	586	Q9UL68