Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	PMG	KRTAP13-1 KRTAP13-2 KRTAP13-3	6.01e-07	13	25	3	PF05287
Domain	KRTAP_PMG	KRTAP13-1 KRTAP13-2 KRTAP13-3	6.01e-07	13	25	3	IPR007951
Domain	DSL	DLL1 DLL4	1.03e-05	4	25	2	PF01414
Domain	DSL	DLL1 DLL4	1.03e-05	4	25	2	SM00051
Domain	DSL	DLL1 DLL4	1.72e-05	5	25	2	IPR001774
Domain	DSL	DLL1 DLL4	1.72e-05	5	25	2	PS51051
Domain	Notch_ligand_N	DLL1 DLL4	1.72e-05	5	25	2	IPR011651
Domain	MNNL	DLL1 DLL4	1.72e-05	5	25	2	PF07657
Domain	TSP_1	PAPLN ISM2 ADGRB1	7.98e-05	63	25	3	PF00090
Domain	TSP1	PAPLN ISM2 ADGRB1	8.76e-05	65	25	3	SM00209
Domain	TSP1_rpt	PAPLN ISM2 ADGRB1	8.76e-05	65	25	3	IPR000884
Domain	TSP1	PAPLN ISM2 ADGRB1	8.76e-05	65	25	3	PS50092
Domain	EGF	DLL1 DLL4 ITGB5	6.19e-04	126	25	3	PF00008
Domain	Growth_fac_rcpt_	DLL1 DLL4 ELAPOR1	1.15e-03	156	25	3	IPR009030
Domain	EGF_extracell	DLL4 ITGB5	2.90e-03	60	25	2	IPR013111
Domain	EGF_2	DLL4 ITGB5	2.90e-03	60	25	2	PF07974
Domain	EGF	DLL1 DLL4 ITGB5	3.69e-03	235	25	3	SM00181
Domain	EGF_1	DLL1 DLL4 ITGB5	4.63e-03	255	25	3	PS00022
Domain	EGF-like_CS	DLL1 DLL4 ITGB5	4.94e-03	261	25	3	IPR013032
Domain	EGF_2	DLL1 DLL4 ITGB5	5.16e-03	265	25	3	PS01186
Domain	ASX_HYDROXYL	DLL1 DLL4	7.86e-03	100	25	2	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	DLL1 DLL4	8.79e-03	106	25	2	IPR000152
Domain	EGF_CA	DLL1 DLL4	1.15e-02	122	25	2	SM00179
Domain	EGF-like_Ca-bd_dom	DLL1 DLL4	1.19e-02	124	25	2	IPR001881
Pathway	REACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT	DLL1 DLL4	2.53e-05	7	16	2	M27199
Pathway	KEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY	DLL1 DLL4	2.53e-05	7	16	2	M47805
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION	DLL1 DLL4	4.33e-05	9	16	2	M47866
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	DLL1 DLL4	9.35e-05	13	16	2	M47423
Pathway	REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER	DLL1 DLL4	1.26e-04	15	16	2	M27202
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	DLL1 DLL4	1.44e-04	16	16	2	M47424
Pathway	WP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION	DLL1 DLL4	1.63e-04	17	16	2	M39389
Pathway	REACTOME_SIGNALING_BY_NOTCH3	DLL1 DLL4	2.04e-04	19	16	2	MM15594
Pathway	REACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	DLL1 DLL4	2.75e-04	22	16	2	M27210
Pathway	REACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	DLL1 DLL4	3.57e-04	25	16	2	M27879
Pathway	WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING	DLL1 DLL4	4.17e-04	27	16	2	M39545
Pathway	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	DLL1 DLL4	5.51e-04	31	16	2	M592
Pathway	REACTOME_SIGNALING_BY_NOTCH2	DLL1 DLL4	6.25e-04	33	16	2	M604
Pathway	REACTOME_KERATINIZATION	KRTAP13-1 KRTAP13-2 KRTAP13-3	6.33e-04	153	16	3	MM15343
Pathway	REACTOME_SIGNALING_BY_NOTCH	DLL1 DLL4	8.73e-04	39	16	2	MM14604
Pathway	WP_NOTCH_SIGNALING_WP268	DLL1 DLL4	1.16e-03	45	16	2	M39571
Pathway	WP_NOTCH_SIGNALING_PATHWAY	DLL1 DLL4	1.21e-03	46	16	2	MM15971
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	DLL1 DLL4	1.27e-03	47	16	2	M7946
Pathway	REACTOME_SIGNALING_BY_NOTCH3	DLL1 DLL4	1.38e-03	49	16	2	M618
Pathway	REACTOME_KERATINIZATION	KRTAP13-1 KRTAP13-2 KRTAP13-3	1.74e-03	217	16	3	M27640
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	DLL1 DLL4	1.92e-03	58	16	2	M29616
Pathway	PID_NOTCH_PATHWAY	DLL1 DLL4	1.99e-03	59	16	2	M17
Pathway	WP_NOTCH_SIGNALING_WP61	DLL1 DLL4	2.13e-03	61	16	2	M39540
Pathway	REACTOME_SIGNALING_BY_NOTCH1	DLL1 DLL4	3.11e-03	74	16	2	M616
Pathway	WP_DELTANOTCH_SIGNALING_PATHWAY	DLL1 DLL4	3.80e-03	82	16	2	MM15922
Pubmed	Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo.	DLL1 DLL4	5.80e-07	2	27	2	15146182
Pubmed	Induction of T-cell development by Delta-like 4-expressing fibroblasts.	DLL1 DLL4	5.80e-07	2	27	2	23988616
Pubmed	Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes.	DLL1 DLL4	5.80e-07	2	27	2	20548034
Pubmed	In vivo and in absence of a thymus, the enforced expression of the Notch ligands delta-1 or delta-4 promotes T cell development with specific unique effects.	DLL1 DLL4	5.80e-07	2	27	2	15728481
Pubmed	Isolation and characterization of the notch ligand delta4.	DLL1 DLL4	5.80e-07	2	27	2	11035934
Pubmed	Delta-like 1 and Delta-like 4 differently require their extracellular domains for triggering Notch signaling in mice.	DLL1 DLL4	5.80e-07	2	27	2	31934853
Pubmed	Suppression of Th2 cell development by Notch ligands Delta1 and Delta4.	DLL1 DLL4	5.80e-07	2	27	2	18209061
Pubmed	Dengue virus up-regulates expression of notch ligands Dll1 and Dll4 through interferon-β signalling pathway.	DLL1 DLL4	5.80e-07	2	27	2	25041739
Pubmed	DLL1- and DLL4-Mediated Notch Signaling Is Essential for Adult Pancreatic Islet Homeostasis.	DLL1 DLL4	5.80e-07	2	27	2	32029480
Pubmed	Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development.	DLL1 DLL4	5.80e-07	2	27	2	16393955
Pubmed	Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.	DLL1 DLL4	1.74e-06	3	27	2	23839946
Pubmed	Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.	DLL1 DLL4	1.74e-06	3	27	2	21372153
Pubmed	Lack of Delta like 1 and 4 expressions in nude thymus anlages.	DLL1 DLL4	1.74e-06	3	27	2	16095582
Pubmed	Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines.	DLL1 DLL4	1.74e-06	3	27	2	12684674
Pubmed	Isolation of a gene expressed during early embryogenesis from the region of 22q11 commonly deleted in DiGeorge syndrome.	TANGO2 AFP	1.74e-06	3	27	2	8268909
Pubmed	The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.	DLL1 DLL4 ITGB5	2.69e-06	35	27	3	28402857
Pubmed	Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.	DLL1 DLL4	3.48e-06	4	27	2	18824585
Pubmed	Role of recycling, Mindbomb1 association, and exclusion from lipid rafts of δ-like 4 for effective Notch signaling to drive T cell development.	DLL1 DLL4	3.48e-06	4	27	2	23162128
Pubmed	Notch ligands transduce different magnitudes of signaling critical for determination of T-cell fate.	DLL1 DLL4	3.48e-06	4	27	2	20602435
Pubmed	Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.	DLL1 DLL4	3.48e-06	4	27	2	28319044
Pubmed	Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.	DLL1 DLL4	3.48e-06	4	27	2	32820046
Pubmed	No evidence for a functional role of bi-directional Notch signaling during angiogenesis.	DLL1 DLL4	3.48e-06	4	27	2	23300864
Pubmed	Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.	KRTAP13-1 KRTAP13-2 KRTAP13-3	4.04e-06	40	27	3	12359730
Pubmed	Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.	DLL1 DLL4	5.80e-06	5	27	2	21726900
Pubmed	Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.	DLL1 DLL4	5.80e-06	5	27	2	30181175
Pubmed	Neuralized-2: expression in human and rodents and interaction with Delta-like ligands.	DLL1 DLL4	5.80e-06	5	27	2	19723503
Pubmed	Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms.	DLL1 DLL4	5.80e-06	5	27	2	19110448
Pubmed	Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches.	DLL1 DLL4	8.69e-06	6	27	2	19217325
Pubmed	Mesenchymal stromal cell-derived septoclasts resorb cartilage during developmental ossification and fracture healing.	DLL1 DLL4	8.69e-06	6	27	2	35091558
Pubmed	Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells.	DLL1 DLL4	8.69e-06	6	27	2	19050235
Pubmed	Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis.	DLL1 DLL4	1.22e-05	7	27	2	24025447
Pubmed	Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo.	DLL1 DLL4	1.22e-05	7	27	2	26114479
Pubmed	GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.	DLL1 DLL4	1.22e-05	7	27	2	32060138
Pubmed	The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.	DLL1 DLL4	1.22e-05	7	27	2	30289388
Pubmed	Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells.	DLL1 DLL4	1.22e-05	7	27	2	21238454
Pubmed	Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.	DLL1 DLL4	1.22e-05	7	27	2	27576369
Pubmed	Endothelial Notch activity promotes angiogenesis and osteogenesis in bone.	DLL1 DLL4	1.62e-05	8	27	2	24647000
Pubmed	Tie2 regulates endocardial sprouting and myocardial trabeculation.	DLL1 DLL4 AFP	2.02e-05	68	27	3	31112136
Pubmed	Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.	DLL1 DLL4	2.08e-05	9	27	2	28714968
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	DLL1 DLL4	2.08e-05	9	27	2	16245338
Pubmed	Monitoring Notch1 activity in development: evidence for a feedback regulatory loop.	DLL1 DLL4	2.08e-05	9	27	2	17685488
Pubmed	Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.	DLL1 DLL4	2.08e-05	9	27	2	20727173
Pubmed	Notch signaling is essential for vascular morphogenesis in mice.	DLL1 DLL4	2.08e-05	9	27	2	10837027
Pubmed	Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium.	DLL1 DLL4	2.08e-05	9	27	2	17605079
Pubmed	Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.	KRTAP13-1 KRTAP13-2 KRTAP13-3	2.11e-05	69	27	3	18721477
Pubmed	Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.	DLL1 DLL4	2.60e-05	10	27	2	23665443
Pubmed	Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.	DLL1 DLL4	2.60e-05	10	27	2	24015274
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	PAPLN ISM2 ADGRB1	2.71e-05	75	27	3	20637190
Pubmed	Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.	DLL1 DLL4	3.81e-05	12	27	2	15465494
Pubmed	Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.	DLL1 DLL4	4.50e-05	13	27	2	11578869
Pubmed	Notch signaling is required for the maintenance of enteric neural crest progenitors.	DLL1 DLL4	4.50e-05	13	27	2	18832397
Pubmed	Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.	DLL1 DLL4	5.25e-05	14	27	2	14757642
Pubmed	Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.	DLL1 DLL4	6.06e-05	15	27	2	12971992
Pubmed	Synergistic, context-dependent, and hierarchical functions of epithelial components in thymic microenvironments.	DLL1 DLL4	6.92e-05	16	27	2	22464328
Pubmed	Expression of Notch pathway components in fetal and adult mouse small intestine.	DLL1 DLL4	6.92e-05	16	27	2	12617809
Pubmed	A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs.	DLL1 DLL4	6.92e-05	16	27	2	35577801
Pubmed	An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.	DLL1 DLL4	6.92e-05	16	27	2	17273555
Pubmed	Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.	DLL1 DLL4	7.84e-05	17	27	2	18694942
Pubmed	Segmental expression of Notch and Hairy genes in nephrogenesis.	DLL1 DLL4	7.84e-05	17	27	2	15821257
Pubmed	Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.	DLL1 DLL4	7.84e-05	17	27	2	23362346
Pubmed	Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.	DLL1 DLL4	7.84e-05	17	27	2	39315665
Pubmed	Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.	DLL1 DLL4	8.81e-05	18	27	2	18093989
Pubmed	RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.	DLL1 DLL4	8.81e-05	18	27	2	15689374
Pubmed	Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.	DLL1 DLL4	9.84e-05	19	27	2	18505817
Pubmed	RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.	DLL1 DLL4	9.84e-05	19	27	2	20335360
Pubmed	Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.	DLL1 DLL4	9.84e-05	19	27	2	16518823
Pubmed	Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.	DLL1 DLL4	9.84e-05	19	27	2	25691540
Pubmed	Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.	DLL1 AFP	1.09e-04	20	27	2	15979417
Pubmed	A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development.	DLL1 DLL4	1.09e-04	20	27	2	12588999
Pubmed	Mesenchymal cells are required for functional development of thymic epithelial cells.	DLL1 DLL4	1.21e-04	21	27	2	17625108
Pubmed	Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.	DLL1 DLL4	1.21e-04	21	27	2	28656980
Pubmed	Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation.	DLL1 DLL4	1.21e-04	21	27	2	31631837
Pubmed	The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.	DLL1 DLL4	1.21e-04	21	27	2	19686682
Pubmed	Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.	DLL1 DLL4	1.33e-04	22	27	2	21750033
Pubmed	Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.	DLL1 DLL4	1.45e-04	23	27	2	36239412
Pubmed	Acheate-scute like 1 (Ascl1) is required for normal delta-like (Dll) gene expression and notch signaling during retinal development.	DLL1 DLL4	1.45e-04	23	27	2	19191219
Pubmed	Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.	DLL1 DLL4	1.45e-04	23	27	2	24337118
Pubmed	Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.	DLL1 DLL4	1.45e-04	23	27	2	14701881
Pubmed	Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.	DLL1 DLL4	1.45e-04	23	27	2	19897741
Pubmed	Hemodynamic force is required for vascular smooth muscle cell recruitment to blood vessels during mouse embryonic development.	DLL1 DLL4	1.59e-04	24	27	2	30796970
Pubmed	The E3 ligase Mind bomb-1 (Mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord.	DLL1 DLL4	1.72e-04	25	27	2	23223237
Pubmed	Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity.	DLL1 DLL4	1.72e-04	25	27	2	19389377
Pubmed	Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain.	DLL1 DLL4	1.86e-04	26	27	2	26912775
Pubmed	Notch signaling controls liver development by regulating biliary differentiation.	DLL1 DLL4	1.86e-04	26	27	2	19369401
Pubmed	Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.	DLL1 DLL4	2.01e-04	27	27	2	21791528
Pubmed	Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.	DLL1 DLL4	2.01e-04	27	27	2	22323600
Pubmed	Notch signaling is essential for ventricular chamber development.	DLL1 DLL4	2.01e-04	27	27	2	17336907
Pubmed	Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo.	DLL1 AFP	2.17e-04	28	27	2	16109169
Pubmed	FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac.	DLL4 AFP	2.17e-04	28	27	2	35297995
Pubmed	EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition.	DLL1 ITGB5	2.33e-04	29	27	2	18794329
Pubmed	Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.	DLL1 DLL4	2.33e-04	29	27	2	25535917
Pubmed	Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.	ZFYVE27 NBEAL1 CTSC	2.44e-04	157	27	3	12466305
Pubmed	Notch signaling regulates ovarian follicle formation and coordinates follicular growth.	DLL1 DLL4	2.49e-04	30	27	2	24552588
Pubmed	Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.	DLL1 DLL4	3.02e-04	33	27	2	16000382
Pubmed	Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.	DLL1 DLL4	3.21e-04	34	27	2	17015435
Pubmed	Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.	DLL1 DLL4	3.21e-04	34	27	2	21311046
Pubmed	Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.	DLL1 DLL4	3.40e-04	35	27	2	21252157
Pubmed	A mutually stimulating loop involving emx2 and canonical wnt signalling specifically promotes expansion of occipital cortex and hippocampus.	CCNA1 DLL1	3.60e-04	36	27	2	15800025
Pubmed	Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.	DLL1 DLL4	4.67e-04	41	27	2	22675208
Pubmed	The notch pathway positively regulates programmed cell death during erythroid differentiation.	DLL1 DLL4	5.38e-04	44	27	2	17476283
Cytoband	21q22.1	KRTAP13-1 KRTAP13-2 KRTAP13-3	1.63e-06	39	27	3	21q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr21q22	KRTAP13-1 KRTAP13-2 KRTAP13-3	1.39e-03	377	27	3	chr21q22
Cytoband	1q21.3	PIP5K1A FLG2	2.17e-03	117	27	2	1q21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr14q24	PAPLN ISM2	6.17e-03	200	27	2	chr14q24
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	HIPK1 ELAPOR1	6.84e-03	211	27	2	chr1p13
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	UPK3BL2 UPK3BL1	7.35e-03	219	27	2	chr7q22
GeneFamily	Keratin associated proteins	KRTAP13-1 KRTAP13-2 KRTAP13-3	9.20e-05	109	15	3	619
Coexpression	IWANAGA_CARCINOGENESIS_BY_KRAS_DN	UPK3BL2 DLL1 ITGB5 UPK3BL1	7.83e-06	135	25	4	MM753
Coexpression	ZENG_GU_ICB_CONTROL_METAGENE_31_PRECICTIVE_ICB_RESISTANCE	PAPLN ZSCAN10 ISM2 ADGRB1	3.74e-05	201	25	4	MM17086
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	DLL1 DLL4	1.04e-04	16	25	2	M2207
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	DLL1 DLL4	1.04e-04	16	25	2	MM1296
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	ZSCAN10 ISM2 DLL4	1.37e-05	77	27	3	22e8c486ad82773b1facd8dd55ed3f448612c600
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	ZSCAN10 ISM2 DLL4	1.37e-05	77	27	3	9743d4a79c8694f76ab780b9e52b4c6ac1af33ed
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)\|Thalamus / BrainAtlas - Mouse McCarroll V32	ZSCAN10 ISM2 DLL4	1.37e-05	77	27	3	7e30a46aa68a9374c4c99385a383e0865ff45b1c
Disease	cancer (implicated_via_orthology)	PIP5K1A DLL1 DLL4 ITGB5	4.28e-05	268	22	4	DOID:162 (implicated_via_orthology)
Disease	treatment resistant depression, response to antidepressant	KRTAP13-1 KRTAP13-3	1.10e-04	21	22	2	EFO_0009854, GO_0036276
Disease	renal cell carcinoma (is_marker_for)	DLL4 AFP ADGRB1	1.16e-04	128	22	3	DOID:4450 (is_marker_for)
Disease	perivascular space measurement	NBEAL1 ITGB5	2.28e-04	30	22	2	EFO_0803382
Disease	dilated cardiomyopathy (implicated_via_orthology)	DLL1 DLL4	1.62e-03	80	22	2	DOID:12930 (implicated_via_orthology)
Disease	stroke outcome severity measurement	TANGO2 TTC7B	3.25e-03	114	22	2	EFO_0009603
Disease	Mammary Neoplasms, Human	DLL1 DLL4 AFP	6.71e-03	525	22	3	C1257931
Disease	Mammary Carcinoma, Human	DLL1 DLL4 AFP	6.71e-03	525	22	3	C4704874
Disease	Mammary Neoplasms	DLL1 DLL4 AFP	6.78e-03	527	22	3	C1458155
Disease	Breast Carcinoma	DLL1 DLL4 AFP	7.17e-03	538	22	3	C0678222
Disease	Malignant neoplasm of breast	DLL1 DLL4 AFP ELAPOR1	7.56e-03	1074	22	4	C0006142

Protein segments in the cluster

Peptide	Gene	Start	Entry
YTCFNSCRSTSLSGP	UPK3BL1	226	B0FP48
CVSSSYSTQCSGPLR	ADGRB1	381	O14514
RVRCYSGCASGSGRQ	C2orf48	46	Q96LS8
CSRYSSGASIGCTPT	ARMC6	6	Q6NXE6
SNSGQRSYTCTCRPG	DLL4	301	Q9NR61
PFTSCCIGSAGQRTT	NBEAL1	706	Q6ZS30
SGCGRPQNASSSCQS	FLG2	286	Q5D862
SSGCCITPTGYRAQR	HIPK1	1021	Q86Z02
SYSNGSDCTRCPAGT	ELAPOR1	401	Q6UXG2
NCSTGKQQRTRPCGY	ISM2	341	Q6H9L7
PNSARCNGSGTYVCG	ITGB5	471	P18084
RRAGSSGNSCITYQP	PIP5K1A	471	Q99755
NTGQGSYTCSCRPGY	DLL1	306	O00548
TCGQGITRIRCYSGS	CCNA1	96	P78396
VSPVRNQASCGSCYS	CTSC	246	P53634
QPSRGSCALSSRQYG	FRMD6-AS1	186	P0C7T7
CSPSTCQLGSSLYRG	KRTAP13-1	41	Q8IUC0
SCQSSCYRPTCGSGF	KRTAP13-1	156	Q8IUC0
CSPSTCQLGSSLYRG	KRTAP13-2	41	Q52LG2
CSPSTCQLGSSLYRG	KRTAP13-3	41	Q3SY46
GCTYSQRRFCPSIQG	FBXO30	561	Q8TB52
GVGQCCTSSYANRRP	AFP	496	P02771
YTCFNSCRSTSLSGP	UPK3BL2	226	E5RIL1
GSRGSYRTRSRCCTS	TBC1D26	231	Q86UD7
PYSCTQCGRSFSRNS	ZSCAN10	696	Q96SZ4
RPCYSQRRDGGSSCV	PAPLN	51	O95428
RYPTNNFGNCTGCSA	ZFYVE27	341	Q5T4F4
CYNLTNPSDSGRGSS	TTC7B	616	Q86TV6
AVCVRCPGYGTRTNT	TANGO2	226	Q6ICL3