Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

ZNRF4 ERBIN

9.89e-064272GO:0070433
GeneOntologyBiologicalProcessnegative regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

ZNRF4 ERBIN

9.89e-064272GO:0070425
GeneOntologyBiologicalProcessanimal organ morphogenesis

TBX15 HIPK2 DLG5 NTNG2 IGF1R CSMD1 MDM4 PCNT SP7

2.09e-051269279GO:0009887
GeneOntologyBiologicalProcessresponse to zinc ion starvation

IGF1R SP7

5.91e-059272GO:0120127
GeneOntologyBiologicalProcesscellular response to zinc ion starvation

IGF1R SP7

5.91e-059272GO:0034224
GeneOntologyBiologicalProcessregulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

ZNRF4 ERBIN

9.01e-0511272GO:0070432
GeneOntologyBiologicalProcessregulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

ZNRF4 ERBIN

1.96e-0416272GO:0070424
GeneOntologyBiologicalProcessnucleotide-binding oligomerization domain containing 2 signaling pathway

ZNRF4 ERBIN

3.09e-0420272GO:0070431
DomainPDZ

DLG5 ERBIN PCLO

1.18e-03151263PS50106
DomainPDZ

DLG5 ERBIN PCLO

1.20e-03152263IPR001478
Domain-

CSMD1 ZZEF1

2.37e-03522622.60.120.290
DomainCUB_dom

CSMD1 ZZEF1

2.84e-0357262IPR000859
DomainEGF-like_CS

NTNG2 ZNRF4 ADGRL4

5.53e-03261263IPR013032
Domain-

DLG5 NLRP14

7.38e-03932621.10.533.10
DomainDEATH-like_dom

DLG5 NLRP14

8.32e-0399262IPR011029
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

NAV2 NTNG2 TTC28 ERBIN PCNT

7.79e-0722527512168954
Pubmed

Insulin-like growth factor 1 receptor (IGF1R) signaling regulates osterix expression and cartilage matrix mineralization during endochondral ossification.

IGF1R SP7

1.74e-06327226475121
Pubmed

MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response.

HIPK2 MDM4

3.48e-06427225961923
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

HIPK2 DLG5 MDM4 TTC28 ZNF180 PCNT

4.98e-0658827638580884
Pubmed

Egr-1 and Hipk2 are required for the TrkA to p75(NTR) switch that occurs downstream of IGF1-R.

HIPK2 IGF1R

1.22e-05727218378044
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DLG5 FAM193A TTC28 ERBIN

2.00e-0520927436779422
Pubmed

Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.

IGF1R IL6ST

2.60e-051027219124510
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NAV2 DLG5 IGF1R MDM4 TTC28 ERBIN

4.29e-0586127636931259
Pubmed

Mesenchyme-specific overexpression of nucleolar protein 66 in mice inhibits skeletal growth and bone formation.

IGF1R SP7

4.50e-051327225746793
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

DLG5 FAM193A TTC28 ERBIN

4.89e-0526327434702444
Pubmed

Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation.

IGF1R SP7

6.92e-051627225736226
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HIPK2 TUT4 IGF1R CSMD1 MDM4 ERBIN PCNT

1.09e-04148927728611215
Pubmed

Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice.

DLG5 PCNT

2.66e-043127217765678
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DLG5 ZZEF1 PCNT

4.07e-0418727326460568
Pubmed

Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis.

IGF1R PCNT

5.14e-044327227664421
Pubmed

Replication of previous genome-wide association studies of bone mineral density in premenopausal American women.

CSMD1 SP7

5.38e-044427220200978
Pubmed

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.

MUC16 GDI2

5.88e-044627219190083
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

DLG5 TTC28 ERBIN

6.19e-0421627331519766
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NAV2 DLG5 ZZEF1 GPATCH2L

7.03e-0452927414621295
Pubmed

Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.

ZZEF1 PCNT

7.51e-04522729455477
GeneFamilyPDZ domain containing

DLG5 ERBIN PCLO

4.33e-041521831220
GeneFamilyFibronectin type III domain containing

IGF1R IL6ST

1.09e-02160182555
CoexpressionHEVNER_INTERMEDIATE_ZONE_AND_UP_POSTMITOTIC_PROJECTION_NEURONS

NAV2 NTNG2 TTC28

2.75e-0557273MM415
CoexpressionGSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP

HIPK2 IGF1R TTC28 IL6ST

4.84e-05198274M3104
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN

IGF1R FAM193A PCNT

9.10e-0585273M10575
CoexpressionLAKE_ADULT_KIDNEY_C28_INTERSTITIUM

NAV2 TTC28 IL6ST

9.42e-0586273M39247
CoexpressionDE_YY1_TARGETS_DN

HIPK2 GDI2 ERBIN

1.19e-0493273M3278
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV2 NTNG2 IGF1R VSTM1

4.91e-061892743b35022c0619df6db234613aa53a076899ca9562
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV2 NTNG2 IGF1R VSTM1

4.91e-06189274358ff514f1c8aa46067208ddf1b68396d789c130
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A TTC28 IL6ST ADGRL4

5.33e-06193274826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A TTC28 IL6ST ADGRL4

5.33e-0619327487d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A TTC28 IL6ST ADGRL4

5.33e-06193274d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

TUT4 IGF1R MDM4 IL6ST

5.55e-06195274d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellCOVID-19_Severe-immature_Neutrophil|COVID-19_Severe / Disease condition and Cell class

NAV2 NTNG2 IGF1R VSTM1

6.02e-06199274f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCellCOVID-19_Severe-immature_Neutrophil-|COVID-19_Severe / Disease condition and Cell class

NAV2 NTNG2 IGF1R VSTM1

6.02e-0619927442ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC16 DLG5 IGF1R PCLO

6.14e-06200274ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

TUT4 MDM4 IL6ST

1.02e-04151273999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

DLG5 CSMD1 ERBIN

1.04e-041522732ff0980dfd8d430cca14649151d856edef115720
ToppCellControl-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

MUC16 PCLO SP7

1.26e-04162273e3b9b46ce2faff7d099502df14bbf51e9f183f8c
ToppCellControl-Epithelial-Ionocyte|Control / Disease state, Lineage and Cell class

MUC16 PCLO SP7

1.28e-04163273bf09fa39bf3e6b3a776d5e79c30c96df572956a3
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LURAP1 IL6ST ADGRL4

1.50e-04172273a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TUT4 MDM4 TTC28

1.53e-04173273694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

LURAP1 CSMD1 ADGRL4

1.58e-041752730a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A TTC28 ADGRL4

1.72e-04180273423454e3390080ae03bb3cbb267255ebfe4df080
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A TTC28 ADGRL4

1.72e-04180273dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 IL6ST ADGRL4

1.74e-04181273fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

TUT4 ERBIN IL6ST

1.77e-04182273877b6e611626628e709568747512f2827ebb2795
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TUT4 ERBIN IL6ST

1.77e-04182273b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TUT4 ERBIN IL6ST

1.77e-041822731aea96ee211f7b9caef7fd385233f51be6021a73
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TUT4 ERBIN IL6ST

1.77e-04182273c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TUT4 ERBIN IL6ST

1.77e-041822734cb182ef39be2044a6ad7266f332d4177591e550
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Mild / Disease group, lineage and cell class

TUT4 ERBIN IL6ST

1.80e-041832737717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM124A TTC28 ADGRL4

1.83e-04184273842473fa415575441b595073a994b6d621169776
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

CSMD1 TTC28 ADGRL4

1.83e-041842730f19494789f38ab1a420545e15e748ca7eb345c3
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R IL6ST ADGRL4

1.86e-04185273742350093d90f96735dc73e3360cdd749bae63fd
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

1.86e-04185273bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R IL6ST ADGRL4

1.89e-0418627390d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R IL6ST ADGRL4

1.89e-041862732cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 CSMD1 PCLO

1.89e-0418627323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

CSMD1 TTC28 ADGRL4

1.92e-0418727381affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R TTC28 IL6ST

1.95e-041882732b630b0609d4ac61338d6533cb7893cfe1241e44
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

1.95e-041882730aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 TTC28 PCLO

1.95e-04188273a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

HIPK2 IL6ST ADGRL4

1.98e-04189273c81787a8c662db5d7814c583dd64562857629e81
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

1.98e-04189273ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CSMD1 IL6ST ADGRL4

1.98e-041892737346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.01e-0419027325525fee1da8a808034d9c916159fd0b6b26bce8
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.01e-04190273a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.04e-0419127388f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV2 NTNG2 VSTM1

2.04e-041912736c1283d51a845cff67ed5e500f7e944165297b53
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CSMD1 TTC28 ADGRL4

2.04e-0419127350601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUT4 IGF1R IL6ST

2.04e-04191273696921a4f160b6b55698652488ed781e855e5e51
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TUT4 IGF1R IL6ST

2.04e-04191273d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCelldroplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 IL6ST ADGRL4

2.04e-04191273c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.04e-041912731924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 TTC28 PCLO

2.04e-041912733387b95a3f2445c672d407922fdce3a91eabaef8
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 IL6ST ADGRL4

2.04e-041912739fc674a58f20b47255e4457d5195c8cff17b0414
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTC28 IL6ST ADGRL4

2.08e-041922731990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGF1R TTC28 IL6ST

2.08e-0419227332927ef3b93e0497e9bbe63c2754da03cf178202
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HIPK2 TTC28 ADGRL4

2.08e-0419227327ff3621e177e7932dd44dd6baa81551ea75a874
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTC28 IL6ST ADGRL4

2.08e-04192273845cc9c18b4436b07dd3ce7980052683937546d2
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.08e-041922735890076929598e88fe9d59a4e4e858b446746ce9
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

NAV2 NTNG2 VSTM1

2.08e-0419227386d561c30554ff04c21801d4aaf8e3c9efe49af4
ToppCellCOVID-19_Severe-Myeloid_G-immature_Neutrophil|COVID-19_Severe / Disease group, lineage and cell class

NAV2 NTNG2 VSTM1

2.08e-04192273303deb68da2e4a75e6ee5a79478182a8bc41c7c5
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.08e-041922736806a1a9fe00395dc1abc3e0124b4261dc701f31
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTC28 IL6ST ADGRL4

2.08e-04192273c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.08e-04192273d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.08e-041922732bfac6b3956265205ca47d06888851ed68b65999
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

HIPK2 NAV2 DLG5

2.08e-04192273e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBIN IL6ST ADGRL4

2.11e-041932738084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.11e-041932734a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

TUT4 TTC28 ERBIN

2.11e-04193273e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.11e-04193273d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.11e-041932732483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.14e-04194273c8b9551b93a5aed62154b487db90130604a6125c
ToppCellCOVID_vent-Myeloid-Monocytic-Developing_Neutrophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

NAV2 NTNG2 VSTM1

2.17e-04195273de23409b1b4146b8ae286850b829ec8dceed0117
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 TTC28 PCLO

2.17e-041952733e519cffa6144a62b06124642a14c9ff39b76554
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R TTC28 PCLO

2.17e-04195273bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.17e-04195273126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 TTC28 PCLO

2.17e-041952737796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

NAV2 IGF1R TTC28

2.20e-04196273ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDI2 ERBIN IL6ST

2.20e-04196273151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCellsevere-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HIPK2 NAV2 VSTM1

2.24e-041972739599319dd1f80c81356a8624131566cc76d77d7e
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.24e-04197273d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

TUT4 MDM4 ERBIN

2.24e-041972735c33454b10023decd2f5ccda9229b6512659711e
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A IL6ST ADGRL4

2.24e-04197273412091994196a06c2779b4c2cfed84be889a5f8d
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GDI2 IL6ST ADGRL4

2.27e-041982736b8baa0b76242736f6dba482cdaad019256877ea
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

NAV2 IGF1R TTC28

2.27e-041982731996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GDI2 IL6ST ADGRL4

2.27e-041982738519c7bd5f6c5a97f5e43f4729b1411d3b07e4c8
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

TUT4 MDM4 ERBIN

2.27e-0419827344417089b62056269cac38d3134ff209c05b7007
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TUT4 MDM4 ERBIN

2.27e-0419827328ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellParenchyma_COVID-19-Endothelial-TX-Artery|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

FAM124A TTC28 ADGRL4

2.34e-0420027334b279804475ea58fbb052b96f44128c082627a9
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DLG5 IGF1R PCLO

2.34e-0420027397f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FAM124A TTC28 ADGRL4

2.34e-042002738552cc7a439449b30b59760c3e8667217b9852b5
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAM124A TTC28 ADGRL4

2.34e-042002735ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCellsevere-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NTNG2 IGF1R VSTM1

2.34e-042002735ee43386da8261d2e7602a152e6ba4338d844e08
ToppCellsevere-immature_Neutrophil|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NTNG2 IGF1R VSTM1

2.34e-04200273a9b87accdaa6956116ab82427e1330e8f007ef94
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAM124A TTC28 ADGRL4

2.34e-0420027345c08f1befe78553bbadcc2fcffb6138306638f3
DrugProcaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A

HIPK2 DLG5 TTC28 GPATCH2L IL6ST

2.88e-061932755430_DN
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A

HIPK2 NAV2 DLG5 MDM4

7.24e-051912745917_UP
DrugMeclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; PC3; HT_HG-U133A

HIPK2 GPATCH2L IL6ST PCLO

7.39e-051922744268_DN
DrugEthoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A

HIPK2 IGF1R MDM4 IL6ST

7.54e-051932744321_DN
DrugSimvastatin [79902-63-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A

IGF1R ZZEF1 GPATCH2L PCLO

7.69e-051942744828_UP
DrugNabumetone [42924-53-8]; Down 200; 17.6uM; MCF7; HT_HG-U133A

HIPK2 MDM4 TTC28 IL6ST

7.85e-051952745428_DN
DrugDiflorasone Diacetate [33564-31-7]; Down 200; 8uM; MCF7; HT_HG-U133A

NAV2 TUT4 ZZEF1 IL6ST

8.00e-051962742798_DN
DrugAcacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A

ZZEF1 GPATCH2L IL6ST PCLO

8.00e-051962743849_DN
Drugclozapine; Down 200; 10uM; HL60; HT_HG-U133A

HIPK2 MDM4 ZZEF1 GPATCH2L

8.16e-051972742689_DN
Drug2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A

HIPK2 NAV2 TTC28 IL6ST

8.32e-051982746969_UP
DrugLidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A

HIPK2 TUT4 TTC28 IL6ST

8.49e-051992746278_UP
DrugProbucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

HIPK2 NAV2 DLG5 GPATCH2L

8.49e-051992743223_DN
Drugdopamine hydrochloride; Down 200; 1uM; MCF7; HG-U133A

ZNRF4 ZZEF1 GPATCH2L ZNF180

8.49e-05199274491_DN
Diseasehypertrophic cardiomyopathy (is_marker_for)

IGF1R ADGRL4

1.01e-0417262DOID:11984 (is_marker_for)
DiseaseDown syndrome (is_marker_for)

GDI2 PCNT

1.71e-0422262DOID:14250 (is_marker_for)
Diseasecoronary aneurysm

NAV2 CSMD1

4.36e-0435262EFO_1000881
Diseasecerebrospinal fluid clusterin measurement

FAM124A CSMD1

4.36e-0435262EFO_0007657
Diseaseinterleukin 2 receptor antagonist measurement

ZNRF4 GDI2

4.36e-0435262EFO_0008332
DiseaseGrowth Disorders

TBX15 IGF1R

4.62e-0436262C0018273
Diseasevital capacity

TBX15 IGF1R MDM4 ZZEF1 PCLO ADGRL4

5.97e-041236266EFO_0004312
Diseaseheart rate variability measurement, response to antipsychotic drug

NAV2 CSMD1

7.55e-0446262EFO_0008003, GO_0097332
DiseaseBipolar Disorder

NTNG2 CSMD1 PCLO PCNT

7.60e-04477264C0005586
Diseaseleft ventricular diastolic function measurement

IGF1R SP7

1.04e-0354262EFO_0008204
Diseaseserum gamma-glutamyl transferase measurement

NAV2 DLG5 NTNG2 IGF1R CSMD1

1.08e-03914265EFO_0004532
DiseaseMajor Depressive Disorder

MDM4 PCLO PCNT

1.25e-03243263C1269683
Diseaseneuroticism measurement, cognitive function measurement

NAV2 FAM193A CSMD1 PCLO

1.43e-03566264EFO_0007660, EFO_0008354
DiseaseAlzheimer's disease (is_marker_for)

IGF1R MDM4 IL6ST

1.46e-03257263DOID:10652 (is_marker_for)
DiseaseUnipolar Depression

MDM4 PCLO PCNT

1.50e-03259263C0041696
Diseaseanorexia nervosa

NTNG2 ADGRL4

1.74e-0370262MONDO_0005351
Diseasepentachlorophenol measurement

MUC16 NTNG2

1.89e-0373262EFO_0022071
Diseaseparathion measurement

MUC16 NTNG2

1.89e-0373262EFO_0022070
Diseasepotassium chromate measurement

MUC16 NTNG2

1.89e-0373262EFO_0022072
Diseasemercuric chloride measurement

MUC16 NTNG2

1.89e-0373262EFO_0022068
Diseaseheptachlor epoxide measurement

MUC16 NTNG2

1.89e-0373262EFO_0022067
Diseasemethoxychlor measurement

MUC16 NTNG2

1.89e-0373262EFO_0022069
Disease4,6-dinitro-o-cresol measurement

MUC16 NTNG2

1.89e-0373262EFO_0022053
Disease2,4,5-trichlorophenol measurement

MUC16 NTNG2

1.89e-0373262EFO_0022052
Diseaseazinphos methyl measurement

MUC16 NTNG2

1.89e-0373262EFO_0022055
Diseasealdrin measurement

MUC16 NTNG2

1.89e-0373262EFO_0022054
Diseasedicofol measurement

MUC16 NTNG2

1.89e-0373262EFO_0022060
Diseasedisulfoton measurement

MUC16 NTNG2

1.89e-0373262EFO_0022062
Diseasedieldrin measurement

MUC16 NTNG2

1.89e-0373262EFO_0022061
Diseaseendrin measurement

MUC16 NTNG2

1.89e-0373262EFO_0022064
Diseaseendosulfan measurement

MUC16 NTNG2

1.89e-0373262EFO_0022063
Diseaseheptachlor measurement

MUC16 NTNG2

1.89e-0373262EFO_0022066
Diseaseethion measurement

MUC16 NTNG2

1.89e-0373262EFO_0022065
Diseasechlorpyrifos measurement

MUC16 NTNG2

1.89e-0373262EFO_0022057
Diseasecadmium chloride measurement

MUC16 NTNG2

1.89e-0373262EFO_0022056
Diseasediazinon measurement

MUC16 NTNG2

1.89e-0373262EFO_0022059
Diseasedibutyl phthalate measurement

MUC16 NTNG2

1.89e-0373262EFO_0022058
Diseaseenvironmental exposure measurement

MUC16 NTNG2

1.89e-0373262EFO_0008360
DiseaseDDT metabolite measurement

MUC16 NTNG2

1.94e-0374262EFO_0007886
Diseasereaction time measurement

NAV2 NTNG2 CSMD1 TTC28

2.48e-03658264EFO_0008393

Protein segments in the cluster

PeptideGeneStartEntry
SEGCELTYSNETHTS

ADGRL4

386

Q9HBW9
EETVTTLDYSHCSLE

ERBIN

21

Q96RT1
IHYESVTLESDSCLD

CSMD1

861

Q96PZ7
TTHDTCSEDTYSTLL

FAM193A

101

P78312
SHVETTSATEELYSS

MUC16

9521

Q8WXI7
SRTYDATTHFETTCD

GDI2

401

P50395
ISCVTVHDSPYSDSS

HIPK2

916

Q9H2X6
YSDCSKLTHSLSTSD

MDM4

331

O15151
YSHLSSTSSELSVEE

FAM124A

26

Q86V42
ASCESDVLHFTSTTT

IGF1R

486

P08069
LHRSSCSEYSPSIES

PCLO

1851

Q9Y6V0
LSLDLSHRTCSDYSE

DLG5

1231

Q8TDM6
TSHCSSLTSSQYSLT

LURAP1

101

Q96LR2
ETRHLSSLDSLESCY

PCNT

961

O95613
DSSHTEYTLSSLTSD

IL6ST

571

P40189
EHTCCYSEASESSLD

GPATCH2L

56

Q9NWQ4
SSSSAHRVLCTEEYS

NTNG2

186

Q96CW9
LTERTSCSFSTHTDL

TBX15

81

Q96SF7
SVSSLHTSCESIDIS

NAV2

1426

Q8IVL1
HSSSDCLPSVYTSLD

SP7

116

Q8TDD2
HCSTTSLEAEYTTVS

ZNRF4

406

Q8WWF5
IYRCSQHSSSSEEST

VSTM1

156

Q6UX27
ESQYKCSETSHSSSL

ZNF180

326

Q9UJW8
ESHYSRACASSETES

TTC28

1306

Q96AY4
SSLCTITDHLDTQYD

ZZEF1

491

O43149
LETESSHQSVCTDTS

TUT4

856

Q5TAX3
RCHFTSLSSEYLSTS

NLRP14

881

Q86W24