Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin filament binding	FLNA FLNB FLNC NEBL CLASP2 NEB PLEC MYO15A	1.22e-04	227	130	8	GO:0051015
GeneOntologyMolecularFunction	structural constituent of muscle	NEBL OBSCN NEB PLEC	1.74e-04	43	130	4	GO:0008307
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL6A1 LAMA2 COL22A1 HMCN1 VCAN MUC5AC TNXB	2.34e-04	188	130	7	GO:0005201
GeneOntologyBiologicalProcess	cellular anatomical entity morphogenesis	FLNC NEBL OBSCN CLASP2 NEB PALS1 TENM4 PLEC	6.66e-06	156	130	8	GO:0032989
GeneOntologyBiologicalProcess	cellular component assembly involved in morphogenesis	FLNC NEBL OBSCN CLASP2 NEB PALS1 TENM4 PLEC	6.66e-06	156	130	8	GO:0010927
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO1 NOMO2 NOMO3	2.00e-05	9	130	3	GO:0160063
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	CPLANE2 CDHR1 KIFAP3 FAT2 TENM4 HMCN1 PTPRG AMIGO3 PCDHB1 CDH5	3.00e-05	313	130	10	GO:0098742
GeneOntologyBiologicalProcess	cardiac muscle thin filament assembly	NEBL NEB	1.18e-04	3	130	2	GO:0071691
GeneOntologyBiologicalProcess	extrathymic T cell selection	BTNL8 BTNL3	1.18e-04	3	130	2	GO:0045062
GeneOntologyCellularComponent	Z disc	FLNA FLNB FLNC ANK1 NEBL OBSCN GRIN2B NEB SYNE2 PLEC	3.92e-08	151	131	10	GO:0030018
GeneOntologyCellularComponent	I band	FLNA FLNB FLNC ANK1 NEBL OBSCN GRIN2B NEB SYNE2 PLEC	9.60e-08	166	131	10	GO:0031674
GeneOntologyCellularComponent	myofibril	COL6A1 FLNA FLNB FLNC ANK1 NEBL OBSCN GRIN2B NEB SYNE2 PLEC	1.23e-06	273	131	11	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	COL6A1 FLNA FLNB FLNC ANK1 NEBL OBSCN GRIN2B NEB SYNE2 PLEC	2.20e-06	290	131	11	GO:0043292
GeneOntologyCellularComponent	sarcomere	FLNA FLNB FLNC ANK1 NEBL OBSCN GRIN2B NEB SYNE2 PLEC	3.92e-06	249	131	10	GO:0030017
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO1 NOMO2 NOMO3	1.97e-05	9	131	3	GO:0160064
GeneOntologyCellularComponent	9+0 non-motile cilium	RPGRIP1L CDHR1 OCRL KIFAP3 PROM1 PHYH VCAN	5.13e-05	153	131	7	GO:0097731
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO1 NOMO2 NOMO3	8.32e-05	14	131	3	GO:0072379
GeneOntologyCellularComponent	cell cortex	UNC13B FLNA FLNB ANK1 FRMPD1 CLASP2 HMCN1 NF2 SEPTIN11 ASTN2	1.18e-04	371	131	10	GO:0005938
GeneOntologyCellularComponent	non-motile cilium	RPGRIP1L CDHR1 OCRL KIFAP3 PROM1 PHYH VCAN	2.40e-04	196	131	7	GO:0097730
GeneOntologyCellularComponent	photoreceptor cell cilium	RPGRIP1L CDHR1 OCRL KIFAP3 PROM1 VCAN	2.45e-04	139	131	6	GO:0097733
GeneOntologyCellularComponent	photoreceptor outer segment	CDHR1 OCRL KIFAP3 PROM1 VCAN	6.75e-04	111	131	5	GO:0001750
GeneOntologyCellularComponent	sarcoplasm	COL6A1 FLNC ANK1 SYNE2 PLEC	7.61e-04	114	131	5	GO:0016528
GeneOntologyCellularComponent	supramolecular fiber	COL6A1 FLNA FLNB FLNC RPGRIP1L ANK1 NEBL MAP6 OBSCN CLASP2 GRIN2B NEB KIFAP3 DNAH12 SYNE2 PLEC TXNDC2	1.12e-03	1179	131	17	GO:0099512
GeneOntologyCellularComponent	anchoring junction	FLNA FLNB FLNC RPGRIP1L OBSCN CLASP2 PALS1 FAT2 HMCN1 NF2 SYNE2 PLEC ABCC2 CDH5 EPHA5	1.19e-03	976	131	15	GO:0070161
GeneOntologyCellularComponent	supramolecular polymer	COL6A1 FLNA FLNB FLNC RPGRIP1L ANK1 NEBL MAP6 OBSCN CLASP2 GRIN2B NEB KIFAP3 DNAH12 SYNE2 PLEC TXNDC2	1.21e-03	1187	131	17	GO:0099081
GeneOntologyCellularComponent	sarcolemma	COL6A1 FLNC ANK1 OBSCN LAMA2 PLEC	1.27e-03	190	131	6	GO:0042383
GeneOntologyCellularComponent	adherens junction	PALS1 FAT2 HMCN1 NF2 CDH5 EPHA5	2.22e-03	212	131	6	GO:0005912
HumanPheno	Neck muscle weakness	COL6A1 FLNC DOK7 OBSCN LAMA2 NEB TOP3A	1.60e-05	95	45	7	HP:0000467
HumanPheno	Abnormality of the musculature of the upper limbs	COL6A1 FLNA FLNB FLNC DOK7 OBSCN LAMA2 NEB SBF2 SYNE2 PLEC	2.39e-05	283	45	11	HP:0001446
HumanPheno	Proximal muscle weakness in upper limbs	FLNC DOK7 OBSCN LAMA2 SBF2 SYNE2	2.45e-05	68	45	6	HP:0008997
HumanPheno	Proximal muscle weakness	COL6A1 FLNC DOK7 OBSCN LAMA2 NEB NF2 SBF2 SYNE2 PLEC TNXB TOP3A	2.48e-05	340	45	12	HP:0003701
HumanPheno	Atypical scarring of skin	COL6A1 FLNA NLRP1 OCRL PLEC TNXB	3.98e-05	74	45	6	HP:0000987
HumanPheno	Muscle fiber splitting	FLNC NEB PLEC TNXB	4.16e-05	23	45	4	HP:0003555
HumanPheno	Limb muscle weakness	COL6A1 FLNC DOK7 OBSCN LAMA2 NEB PHYH VPS13D NF2 SBF2 SYNE2 PLEC	4.28e-05	359	45	12	HP:0003690
HumanPheno	Abnormal muscle fiber morphology	COL6A1 FLNC DOK7 OBSCN LAMA2 NEB PHKA2 SLC25A12 SYNE2 PLEC TNXB	4.37e-05	302	45	11	HP:0004303
HumanPheno	Neck flexor weakness	FLNC DOK7 LAMA2 NEB TOP3A	4.48e-05	46	45	5	HP:0003722
HumanPheno	Elevated circulating creatine kinase concentration	COL6A1 FLNC DOK7 OBSCN LAMA2 OCRL NEB PHKA2 SYNE2 PLEC TOP3A	4.94e-05	306	45	11	HP:0003236
HumanPheno	Increased variability in muscle fiber diameter	COL6A1 OBSCN LAMA2 NEB SLC25A12 SYNE2 PLEC	5.87e-05	116	45	7	HP:0003557
HumanPheno	Accessory carpal bones	FLNA FLNB	7.63e-05	2	45	2	HP:0004232
HumanPheno	Bipartite calcaneus	FLNA FLNB	7.63e-05	2	45	2	HP:0008127
HumanPheno	Abnormality of skeletal muscle fiber size	COL6A1 OBSCN LAMA2 NEB SLC25A12 SYNE2 PLEC	7.69e-05	121	45	7	HP:0012084
HumanPheno	Abnormal circulating creatine kinase concentration	COL6A1 FLNC DOK7 OBSCN LAMA2 OCRL NEB PHKA2 SYNE2 PLEC TOP3A	7.88e-05	322	45	11	HP:0040081
HumanPheno	Abnormal circulating enzyme concentration	COL6A1 FLNC DOK7 OBSCN LAMA2 OCRL NEB PHKA2 SYNE2 PLEC TOP3A	9.32e-05	328	45	11	HP:0011021
HumanPheno	Increased connective tissue	LAMA2 NEB PLEC TNXB	9.32e-05	28	45	4	HP:0009025
HumanPheno	Abnormal morphology of the musculature of the neck	COL6A1 FLNC DOK7 OBSCN LAMA2 NEB VPS13D TOP3A	1.02e-04	171	45	8	HP:0011006
HumanPheno	EMG: myopathic abnormalities	COL6A1 FLNC DOK7 NEB SYNE2 PLEC DISP1	1.16e-04	129	45	7	HP:0003458
HumanPheno	Scapular winging	COL6A1 FLNA FLNB FLNC NEB SYNE2	2.04e-04	99	45	6	HP:0003691
HumanPheno	Scarring	COL6A1 FLNA NLRP1 OCRL PLEC TNXB	2.41e-04	102	45	6	HP:0100699
HumanPheno	Respiratory insufficiency due to muscle weakness	COL6A1 FLNC DOK7 LAMA2 NEB SYNE2	2.54e-04	103	45	6	HP:0002747
HumanPheno	Abnormal motor neuron morphology	COL6A1 FLNC OBSCN LAMA2 OCRL NEB VPS13D SAMD9L NF2 SBF2 SYNE2 PLEC MED17	2.62e-04	501	45	13	HP:0002450
HumanPheno	Functional motor deficit	COL6A1 FLNC DOK7 POLR2A OBSCN LAMA2 NEB PHKA2 VPS13D NF2 PLEC TOP3A	2.79e-04	436	45	12	HP:0004302
HumanPheno	Abnormality of the shoulder girdle musculature	COL6A1 FLNA FLNB FLNC DOK7 NEB SYNE2	2.84e-04	149	45	7	HP:0001435
HumanPheno	Abnormal neuron morphology	COL6A1 FLNC OBSCN LAMA2 OCRL NEB VPS13D SAMD9L NF2 SBF2 SYNE2 PLEC MED17	2.95e-04	507	45	13	HP:0012757
HumanPheno	Upper limb muscle weakness	FLNC DOK7 OBSCN LAMA2 NF2 SBF2 SYNE2	3.08e-04	151	45	7	HP:0003484
HumanPheno	Weakness of muscles of respiration	COL6A1 FLNC DOK7 LAMA2 NEB SYNE2	4.83e-04	116	45	6	HP:0004347
MousePheno	abnormal skeletal muscle fiber size	DOCK1 COL6A1 FLNC OBSCN LAMA2 NEB NR1D1 PLEC	1.09e-05	140	106	8	MP:0009398
MousePheno	abnormal skeletal muscle fiber morphology	DOCK1 COL6A1 FLNC ANK1 OBSCN LAMA2 NEB NR1D1 PLEC	3.30e-05	212	106	9	MP:0003084
MousePheno	myopathy	COL6A1 ANK1 OBSCN LAMA2 PLEC	5.37e-05	54	106	5	MP:0000751
MousePheno	abnormal CD4-positive, gamma-delta intraepithelial T cell morphology	BTNL8 BTNL3	5.70e-05	2	106	2	MP:0008357
MousePheno	decreased CD4-positive, gamma-delta intraepithelial T cell number	BTNL8 BTNL3	5.70e-05	2	106	2	MP:0008359
Domain	-	FLNA FLNB FLNC SEMA7A BTNL8 OBSCN NOMO1 HMCN1 PTPRG AMIGO3 BTNL3 NOMO2 VCAN ASTN1 ASTN2 TNXB NOMO3 ADGRA3 EPHA5	2.13e-07	663	132	19	2.60.40.10
Domain	ACTININ_2	FLNA FLNB FLNC SYNE2 PLEC	4.96e-07	23	132	5	PS00020
Domain	ACTININ_1	FLNA FLNB FLNC SYNE2 PLEC	4.96e-07	23	132	5	PS00019
Domain	Actinin_actin-bd_CS	FLNA FLNB FLNC SYNE2 PLEC	4.96e-07	23	132	5	IPR001589
Domain	Ig-like_fold	FLNA FLNB FLNC SEMA7A BTNL8 OBSCN NOMO1 HMCN1 PTPRG AMIGO3 BTNL3 NOMO2 VCAN ASTN1 ASTN2 TNXB NOMO3 ADGRA3 EPHA5	5.53e-07	706	132	19	IPR013783
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.37e-06	4	132	3	PF09430
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.37e-06	4	132	3	IPR019008
Domain	CarboxyPept-like_regulatory	NOMO1 TENM4 NOMO2 NOMO3	5.28e-06	17	132	4	IPR008969
Domain	Carb-bd-like_fold	NOMO1 NOMO2 NOMO3	1.88e-05	8	132	3	IPR013784
Domain	IG_FLMN	FLNA FLNB FLNC	3.99e-05	10	132	3	SM00557
Domain	Astrotactin	ASTN1 ASTN2	4.96e-05	2	132	2	IPR026995
Domain	Filamin	FLNA FLNB FLNC	5.46e-05	11	132	3	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNB FLNC	5.46e-05	11	132	3	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNB FLNC	5.46e-05	11	132	3	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNB FLNC	5.46e-05	11	132	3	IPR017868
Domain	CarboxyPept_regulatory_dom	NOMO1 NOMO2 NOMO3	9.37e-05	13	132	3	IPR014766
Domain	-	NOMO1 NOMO2 NOMO3	9.37e-05	13	132	3	2.60.40.1120
Domain	CH	FLNA FLNB FLNC SYNE2 PLEC	9.61e-05	65	132	5	SM00033
Domain	EGF_2	LAMA2 FAT2 TENM4 HMCN1 VCAN ASTN1 ASTN2 TNXB EPHA5	1.13e-04	265	132	9	PS01186
Domain	CH	FLNA FLNB FLNC SYNE2 PLEC	1.37e-04	70	132	5	PF00307
Domain	-	FLNA FLNB FLNC SYNE2 PLEC	1.46e-04	71	132	5	1.10.418.10
Domain	VPS13	VPS13C VPS13D	1.48e-04	3	132	2	IPR026847
Domain	VPS13_mid_rpt	VPS13C VPS13D	1.48e-04	3	132	2	PF16910
Domain	VPS13	VPS13C VPS13D	1.48e-04	3	132	2	PF16908
Domain	VPS13_N2	VPS13C VPS13D	1.48e-04	3	132	2	IPR031646
Domain	VPS13_mid_rpt	VPS13C VPS13D	1.48e-04	3	132	2	IPR031642
Domain	CH	FLNA FLNB FLNC SYNE2 PLEC	1.67e-04	73	132	5	PS50021
Domain	CH-domain	FLNA FLNB FLNC SYNE2 PLEC	1.90e-04	75	132	5	IPR001715
Domain	Nebulin	NEBL NEB	2.95e-04	4	132	2	PF00880
Domain	SHR-BD	VPS13C VPS13D	2.95e-04	4	132	2	IPR009543
Domain	NEBULIN	NEBL NEB	2.95e-04	4	132	2	PS51216
Domain	NEBU	NEBL NEB	2.95e-04	4	132	2	SM00227
Domain	Nebulin	NEBL NEB	2.95e-04	4	132	2	IPR013998
Domain	VPS13_C	VPS13C VPS13D	2.95e-04	4	132	2	PF16909
Domain	Multidrug-R_assoc	ABCC3 ABCC2	2.95e-04	4	132	2	IPR005292
Domain	VPS13_C	VPS13C VPS13D	2.95e-04	4	132	2	IPR031645
Domain	Nebulin_repeat	NEBL NEB	2.95e-04	4	132	2	IPR000900
Domain	SHR-BD	VPS13C VPS13D	2.95e-04	4	132	2	PF06650
Domain	FN3	FLNC OBSCN PTPRG ASTN1 ASTN2 TNXB EPHA5	3.47e-04	185	132	7	SM00060
Domain	EGF_1	LAMA2 FAT2 TENM4 HMCN1 VCAN ASTN1 ASTN2 TNXB	4.64e-04	255	132	8	PS00022
Domain	EGF-like_CS	LAMA2 FAT2 TENM4 HMCN1 VCAN ASTN1 TNXB EPHA5	5.41e-04	261	132	8	IPR013032
Domain	FN3_dom	FLNC OBSCN PTPRG ASTN1 ASTN2 TNXB EPHA5	7.19e-04	209	132	7	IPR003961
Domain	SH3	DOCK1 NEBL OBSCN NEB PALS1 SRGAP1 MYO15A	8.73e-04	216	132	7	SM00326
Domain	SH3	DOCK1 NEBL OBSCN NEB PALS1 SRGAP1 MYO15A	8.73e-04	216	132	7	PS50002
Domain	ConA-like_dom	BTNL8 LAMA2 COL22A1 TRIM14 DDX1 FAT2 BTNL3	9.46e-04	219	132	7	IPR013320
Domain	SH3_domain	DOCK1 NEBL OBSCN NEB PALS1 SRGAP1 MYO15A	9.71e-04	220	132	7	IPR001452
Domain	Chorein_N	VPS13C VPS13D	1.35e-03	8	132	2	PF12624
Domain	VPS13_N	VPS13C VPS13D	1.35e-03	8	132	2	IPR026854
Domain	EGF	LAMA2 FAT2 TENM4 HMCN1 VCAN ASTN1 TNXB	1.42e-03	235	132	7	SM00181
Domain	EGF_3	FAT2 TENM4 HMCN1 VCAN ASTN1 ASTN2 TNXB	1.42e-03	235	132	7	PS50026
Domain	zf-C2H2_6	ZNF567 ZNF136 ZFP90 ZNF527 ZNF672 ZNF425 ZNF667 ZNF701	1.77e-03	314	132	8	PF13912
Domain	EGF-like_dom	LAMA2 FAT2 TENM4 HMCN1 VCAN ASTN1 TNXB	1.98e-03	249	132	7	IPR000742
Domain	-	CPLANE2 ABCC3 LONP2 NLRP1 ATAD2 DDX1 PALS1 SAMD9L DNAH12 MOV10L1 SEPTIN11 ABCC2 MYO15A	2.42e-03	746	132	13	3.40.50.300
Domain	FN3	OBSCN PTPRG ASTN1 ASTN2 TNXB EPHA5	2.93e-03	199	132	6	PS50853
Domain	MACPF	ASTN1 ASTN2	3.12e-03	12	132	2	IPR020864
Domain	MACPF	ASTN1 ASTN2	3.12e-03	12	132	2	SM00457
Domain	PRY	BTNL8 TRIM14 BTNL3	3.24e-03	42	132	3	PF13765
Domain	SPRY	BTNL8 TRIM14 DDX1 BTNL3	3.37e-03	87	132	4	SM00449
Domain	AAA	ABCC3 LONP2 ATAD2 DNAH12 ABCC2	3.59e-03	144	132	5	SM00382
Domain	AAA+_ATPase	ABCC3 LONP2 ATAD2 DNAH12 ABCC2	3.59e-03	144	132	5	IPR003593
Domain	SSD	SCAP DISP1	3.67e-03	13	132	2	IPR000731
Domain	SSD	SCAP DISP1	3.67e-03	13	132	2	PS50156
Domain	KRAB	ZNF567 ZNF136 ZFP90 ZNF527 ZNF425 ZNF436 ZNF667 ZNF701	3.96e-03	358	132	8	PS50805
Domain	KRAB	ZNF567 ZNF136 ZFP90 ZNF527 ZNF425 ZNF436 ZNF667 ZNF701	3.96e-03	358	132	8	PF01352
Domain	FERM_M	FRMPD1 NF2 MYO15A	4.20e-03	46	132	3	PF00373
Domain	Myotubularin-like_Pase_dom	MTMR11 SBF2	4.27e-03	14	132	2	IPR010569
Domain	PPASE_MYOTUBULARIN	MTMR11 SBF2	4.27e-03	14	132	2	PS51339
Domain	Myotubularin_fam	MTMR11 SBF2	4.27e-03	14	132	2	IPR030564
Domain	Myotub-related	MTMR11 SBF2	4.27e-03	14	132	2	PF06602
Domain	SPRY	BTNL8 TRIM14 DDX1 BTNL3	4.45e-03	94	132	4	PF00622
Domain	SPRY_dom	BTNL8 TRIM14 DDX1 BTNL3	4.45e-03	94	132	4	IPR003877
Domain	B30.2/SPRY	BTNL8 TRIM14 DDX1 BTNL3	4.62e-03	95	132	4	IPR001870
Domain	B302_SPRY	BTNL8 TRIM14 DDX1 BTNL3	4.62e-03	95	132	4	PS50188
Domain	PRY	BTNL8 TRIM14 BTNL3	4.73e-03	48	132	3	SM00589
Domain	PRY	BTNL8 TRIM14 BTNL3	4.73e-03	48	132	3	IPR006574
Domain	KRAB	ZNF567 ZNF136 ZFP90 ZNF527 ZNF425 ZNF436 ZNF667 ZNF701	4.75e-03	369	132	8	SM00349
Domain	KRAB	ZNF567 ZNF136 ZFP90 ZNF527 ZNF425 ZNF436 ZNF667 ZNF701	4.82e-03	370	132	8	IPR001909
Domain	FERM_central	FRMPD1 NF2 MYO15A	5.02e-03	49	132	3	IPR019748
Domain	FERM_domain	FRMPD1 NF2 MYO15A	5.02e-03	49	132	3	IPR000299
Domain	FERM_1	FRMPD1 NF2 MYO15A	5.31e-03	50	132	3	PS00660
Domain	FERM_2	FRMPD1 NF2 MYO15A	5.31e-03	50	132	3	PS00661
Domain	FERM_3	FRMPD1 NF2 MYO15A	5.31e-03	50	132	3	PS50057
Domain	Band_41_domain	FRMPD1 NF2 MYO15A	5.31e-03	50	132	3	IPR019749
Domain	B41	FRMPD1 NF2 MYO15A	5.31e-03	50	132	3	SM00295
Domain	P-loop_NTPase	CPLANE2 ABCC3 LONP2 NLRP1 ATAD2 DDX1 PALS1 SAMD9L DNAH12 MOV10L1 SEPTIN11 ABCC2 MYO15A	7.07e-03	848	132	13	IPR027417
Pathway	WP_NPHP1_DELETION_SYNDROME	FLNA FLNB FLNC RPGRIP1L	5.90e-07	11	94	4	M48099
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SIN3B ATP13A1 ACSS1 ZBTB4 TRIM14 MEAK7 CEP350 VPS13D FAT2 SAMD9L SCAP ZNF436 SBF2 ASTN2 CCSER1	7.18e-10	493	132	15	15368895
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	UNC13B NOMO1 SLC25A12 NOMO2 SRGAP1 SBF2 ATP12A NOMO3	1.03e-08	110	132	8	27889896
Pubmed	Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.	FLNA FLNB FLNC NEBL NEB NOMO1	1.07e-08	41	132	6	18157088
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	FLNA FLNB FLNC RPGRIP1L MAP6 VPS13C OBSCN VPS13D SLC25A12 VCAN PLEC MYO15A DNAJA1 MUC5AC	3.52e-08	564	132	14	21565611
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO1 NOMO2 NOMO3	5.34e-08	3	132	3	36011023
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNB FLNC	5.34e-08	3	132	3	12393796
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNB FLNC	5.34e-08	3	132	3	11153914
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNB FLNC	5.34e-08	3	132	3	11252955
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO1 NOMO2 NOMO3	5.34e-08	3	132	3	25576386
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	ABCC3 COL6A1 FLNA FLNC OBSCN NEB ABTB1 HNRNPA0 PLEC	1.41e-07	214	132	9	22199357
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	COL6A1 LAMA2 APOB HMCN1 VCAN TNXB	1.67e-07	64	132	6	22261194
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	FLNA FLNB POLR2A ATAD2 DDX1 VCAN HNRNPA0 PLEC DNAJA1	1.71e-07	219	132	9	31353912
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNB FLNC	2.13e-07	4	132	3	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNB FLNC	2.13e-07	4	132	3	22802962
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO1 NOMO2 NOMO3	2.13e-07	4	132	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO1 NOMO2 NOMO3	2.13e-07	4	132	3	9267806
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	UNC13B ABCC3 FLNA FLNC SEMA7A ATP13A1 POLR2A ZBTB4 OBSCN CLASP2 FAAP100 ADCY7 SCAP NF2 SBF2 PLEC CHPF TOP3A	2.15e-07	1105	132	18	35748872
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNB FLNC	5.31e-07	5	132	3	12006559
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNB FLNC	5.31e-07	5	132	3	17360453
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNB FLNC	5.31e-07	5	132	3	19366992
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNA FLNB FLNC	1.85e-06	7	132	3	16076904
Pubmed	WDFY4 is required for cross-presentation in response to viral and tumor antigens.	VPS13C NOMO1 NOMO2 SEPTIN11 PLEC DNAJA1 NOMO3	2.35e-06	156	132	7	30409884
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNA FLNB FLNC	2.95e-06	8	132	3	17145501
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO1 NOMO2 NOMO3	2.95e-06	8	132	3	15257293
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNA FLNB FLNC	4.41e-06	9	132	3	11807098
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO1 NOMO2 NOMO3	4.41e-06	9	132	3	36261522
Pubmed	An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.	NOMO1 NOMO2 TADA2A NOMO3	7.45e-06	33	132	4	30783098
Pubmed	Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.	FLNA FLNB FLNC	8.62e-06	11	132	3	36579465
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO1 NOMO2 NOMO3	8.62e-06	11	132	3	32820719
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ABCC3 ARFGEF1 APOB ATAD2 MEAK7 PREB PROM1 PALS1 PTPRG NF2 ABCC2	1.19e-05	569	132	11	30639242
Pubmed	Butyrophilin-like 1 encodes an enterocyte protein that selectively regulates functional interactions with T lymphocytes.	BTNL8 BTNL3	1.43e-05	2	132	2	21368163
Pubmed	Localization of ank1.5 in the sarcoplasmic reticulum precedes that of SERCA and RyR: relationship with the organization of obscurin in developing sarcomeres.	ANK1 OBSCN	1.43e-05	2	132	2	19002483
Pubmed	A butyrophilin family member critically inhibits T cell activation.	BTNL8 BTNL3	1.43e-05	2	132	2	20944003
Pubmed	Murine astrotactins 1 and 2 have a similar membrane topology and mature via endoproteolytic cleavage catalyzed by a signal peptidase.	ASTN1 ASTN2	1.43e-05	2	132	2	30696770
Pubmed	The ontogeny of Butyrophilin-like (Btnl) 1 and Btnl6 in murine small intestine.	BTNL8 BTNL3	1.43e-05	2	132	2	27528202
Pubmed	Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.	FLNA FLNB	1.43e-05	2	132	2	17635842
Pubmed	Immunohistochemical Assessment of the Expression of Biliary Transportation Proteins MRP2 and MRP3 in Hepatocellular Carcinoma and in Cholangiocarcinoma.	ABCC3 ABCC2	1.43e-05	2	132	2	29464551
Pubmed	Obscurin is a ligand for small ankyrin 1 in skeletal muscle.	ANK1 OBSCN	1.43e-05	2	132	2	12631729
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	1.43e-05	2	132	2	9694715
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	1.43e-05	2	132	2	7689010
Pubmed	Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.	ABCC3 ABCC2	1.43e-05	2	132	2	21841039
Pubmed	Mapping the binding site on small ankyrin 1 for obscurin.	ANK1 OBSCN	1.43e-05	2	132	2	17720975
Pubmed	Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.	FLNA FLNB	1.43e-05	2	132	2	21325628
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	1.43e-05	2	132	2	10679933
Pubmed	Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.	NEBL NEB	1.43e-05	2	132	2	19851499
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	1.43e-05	2	132	2	24469451
Pubmed	Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.	ABCC3 ABCC2	1.43e-05	2	132	2	12704183
Pubmed	A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.	FLNC OBSCN	1.43e-05	2	132	2	29073160
Pubmed	Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.	ABCC3 ABCC2	1.43e-05	2	132	2	25788542
Pubmed	Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma.	ABCC3 ABCC2	1.43e-05	2	132	2	11745434
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	1.43e-05	2	132	2	12525170
Pubmed	Structural and functional aspects of filamins.	FLNA FLNB	1.43e-05	2	132	2	11336782
Pubmed	The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.	FLNA FLNB	1.43e-05	2	132	2	33649519
Pubmed	Isolation of murine hair-inducing cells using the cell surface marker prominin-1/CD133.	PROM1 VCAN	1.43e-05	2	132	2	17185982
Pubmed	Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.	ABCC3 ABCC2	1.43e-05	2	132	2	30959153
Pubmed	Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation.	FLNB SBF2	1.43e-05	2	132	2	19039035
Pubmed	Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.	ABCC3 ABCC2	1.43e-05	2	132	2	19088030
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FLNA FLNB MAP6 FRMPD1 OBSCN CLASP2 APOB METTL14 SCAP NF2 VCAN SBF2 SEPTIN11 PLEC FHIP2B	1.66e-05	1084	132	15	11544199
Pubmed	Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis.	FLNA FLNB PALS1 CDH5	2.18e-05	43	132	4	27664421
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	VPS13C NEB FAT2 SLC25A12 HMCN1 PLEC	2.63e-05	152	132	6	34299191
Pubmed	Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.	FLNC NEBL NEB	2.89e-05	16	132	3	25987543
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	COL6A1 FLNA FLNB NEBL VPS13C AASDHPPT NEB ATAD2 CYRIB PROM1 PALS1 VPS13D MYO15A DNAJA1	3.38e-05	1016	132	14	19056867
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	DOCK1 FLNA FLNB FLNC VPS13D VCAN PLEC	3.39e-05	235	132	7	30258100
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	FLNA FLNB FLNC	4.18e-05	18	132	3	12119179
Pubmed	The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.	ABCC3 ABCC2	4.28e-05	3	132	2	12628490
Pubmed	Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.	FLNA FLNB	4.28e-05	3	132	2	28175289
Pubmed	Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.	ABCC3 ABCC2	4.28e-05	3	132	2	18799096
Pubmed	Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.	ABCC3 ABCC2	4.28e-05	3	132	2	17273943
Pubmed	Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.	FLNA FLNC	4.28e-05	3	132	2	11038172
Pubmed	Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.	ABCC3 ABCC2	4.28e-05	3	132	2	18245269
Pubmed	CD133+ melanoma subpopulations contribute to perivascular niche morphogenesis and tumorigenicity through vasculogenic mimicry.	PROM1 CDH5	4.28e-05	3	132	2	22865455
Pubmed	Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.	ABCC3 ABCC2	4.28e-05	3	132	2	25952649
Pubmed	Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.	ABCC3 ABCC2	4.28e-05	3	132	2	19443695
Pubmed	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.	FLNA FLNC	4.28e-05	3	132	2	11102480
Pubmed	Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers.	ABCC3 ABCC2	4.28e-05	3	132	2	19480556
Pubmed	Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.	FLNA FLNC	4.28e-05	3	132	2	17825253
Pubmed	Mediator and post-recruitment regulation of RNA polymerase II.	POLR2A MED17	4.28e-05	3	132	2	21326907
Pubmed	Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.	ABCC3 ABCC2	4.28e-05	3	132	2	19996279
Pubmed	Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.	ABCC3 ABCC2	4.28e-05	3	132	2	17494643
Pubmed	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.	FLNA FLNC	4.28e-05	3	132	2	9412467
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNA FLNC	4.28e-05	3	132	2	12704190
Pubmed	Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.	ANK1 OBSCN	4.28e-05	3	132	2	12527750
Pubmed	GPIbα regulates platelet size by controlling the subcellular localization of filamin.	FLNA FLNB	4.28e-05	3	132	2	22174152
Pubmed	Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C.	FLNC PLEC	4.28e-05	3	132	2	21223964
Pubmed	Hepatocyte SREBP signaling mediates clock communication within the liver.	NR1D1 SCAP	4.28e-05	3	132	2	37066875
Pubmed	Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides.	ABCC3 ABCC2	4.28e-05	3	132	2	17485564
Pubmed	Ancestry and frequency of genetic variants in the general population are confounders in the characterization of germline variants linked to cancer.	BTNL8 BTNL3	4.28e-05	3	132	2	32375678
Pubmed	Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.	FLNA FLNB	4.28e-05	3	132	2	38989458
Pubmed	Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins.	FLNC OBSCN NEB	4.95e-05	19	132	3	27171814
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	UNC13B FLNA FLNB POLR2A AASDHPPT CLASP2 NOMO1 CEP350 TADA2A DNAJA1 NOMO3	5.27e-05	670	132	11	22990118
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	FLNA FLNB FLNC NOMO1 NOMO2 SEPTIN11 PLEC NOMO3	5.37e-05	344	132	8	30333137
Pubmed	The Effect of the NFκB-USP9X-Cx43 Axis on the Dynamic Balance of Bone Formation/Degradation during Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.	FLNA FLNC APOB SLC25A12	5.41e-05	54	132	4	35391932
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF527 MAP6 ATP13A1 ACSS1 AMIGO3	5.69e-05	107	132	5	11347906
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	ATP13A1 LAMA2 APOB FAT2 PTPRG CDH5 TNXB	5.96e-05	257	132	7	16335952
Pubmed	An Alternative Splicing Program for Mouse Craniofacial Development.	FLNB OCRL SYNE2	6.76e-05	21	132	3	33013468
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	UAP1 APOB GRIN2B SBF2 ANKRD30A ABTB1 NKTR MED17	7.51e-05	361	132	8	18976975
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	FLNA FLNB ATP13A1 VPS13C DDX1 IBTK PLEC	7.75e-05	268	132	7	33024031
Pubmed	Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.	FLNA FLNB FLNC	7.81e-05	22	132	3	18487259
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	POLR2A CLASP2 HVCN1 DDX1 PREB SLC25A12 HNRNPA0 NKTR PLEC MED17 DNAJA1	7.87e-05	701	132	11	30196744
Pubmed	Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover.	ANK1 OBSCN	8.54e-05	4	132	2	22573887
Interaction	NPHP4 interactions	FLNA FLNB FLNC RPGRIP1L VPS13C OBSCN VPS13D SLC25A12 PLEC MUC5AC	3.35e-06	236	131	10	int:NPHP4
GeneFamily	Fibronectin type III domain containing	OBSCN PTPRG ASTN1 ASTN2 TNXB EPHA5	1.99e-04	160	95	6	555
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_UP	LONP2 VPS13C NLRP1 CEP350 PHKA2 VPS13D ASTN2 NKTR	7.90e-06	199	132	8	M4521
Coexpression	BILD_MYC_ONCOGENIC_SIGNATURE	ABCC3 FLNB NLRP1 MON1A MEAK7 MTMR11 ZNF667 PLEC	1.13e-05	209	132	8	M2069
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 OBSCN APOB COL22A1 GRIN2B NEB SORCS1 TENM4 HMCN1 MYO15A EPHA5	8.92e-12	184	132	11	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 OBSCN APOB COL22A1 GRIN2B NEB SORCS1 TENM4 HMCN1 MYO15A EPHA5	8.92e-12	184	132	11	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 OBSCN APOB COL22A1 GRIN2B NEB SORCS1 TENM4 HMCN1 MYO15A EPHA5	8.92e-12	184	132	11	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR64 LAMA2 COL22A1 GRIN2B SORCS1 HMCN1 PTPRG MOV10L1 ASTN1 EPHA5	5.24e-11	160	132	10	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR64 LAMA2 COL22A1 GRIN2B SORCS1 HMCN1 PTPRG MOV10L1 ASTN1 EPHA5	5.24e-11	160	132	10	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	COL6A1 NEBL LAMA2 MOXD1 TENM4 HMCN1 PTPRG VCAN SEPTIN11	7.85e-09	197	132	9	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	COL6A1 NEBL LAMA2 MOXD1 HMCN1 PTPRG SRGAP1 VCAN SEPTIN11	8.21e-09	198	132	9	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	COL6A1 LAMA2 MOXD1 HMCN1 PTPRG SRGAP1 ZNF667 TNXB	9.09e-08	187	132	8	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK1 COL6A1 LAMA2 TENM4 SRGAP1 VCAN SEPTIN11 TNXB	1.11e-07	192	132	8	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A1 FLNB FLNC UAP1 LAMA2 VCAN TNXB DISP1	1.21e-07	194	132	8	7b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	COL6A1 UAP1 LAMA2 MOXD1 TENM4 SRGAP1 VCAN TNXB	1.21e-07	194	132	8	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A1 LAMA2 MOXD1 HMCN1 PTPRG SRGAP1 VCAN SEPTIN11	1.41e-07	198	132	8	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 LAMA2 MOXD1 HMCN1 PTPRG SRGAP1 VCAN TNXB	1.52e-07	200	132	8	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL22A1 GRIN2B MOV10L1 ABCC2 ATP12A MYO15A EPHA5	2.63e-07	145	132	7	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	ABCC3 FLNC NEBL OBSCN TRIM14 CYRIB CCSER1	7.70e-07	170	132	7	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	COL6A1 UAP1 LAMA2 SORCS1 PTPRG VCAN TNXB	1.09e-06	179	132	7	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A1 LAMA2 SORCS1 MOXD1 HMCN1 VCAN TNXB	1.22e-06	182	132	7	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C GRIN2B TENM4 SRGAP1 VCAN ASTN1 PLEC	1.41e-06	186	132	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	COL6A1 LAMA2 TENM4 HMCN1 PTPRG SEPTIN11 TNXB	1.46e-06	187	132	7	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	COL6A1 LAMA2 MOXD1 HMCN1 PTPRG VCAN TNXB	1.62e-06	190	132	7	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK1 ABCC3 NEBL PROM1 SYNE2 ASTN2 ADGRA3	1.68e-06	191	132	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK1 ABCC3 NEBL CYRIB PROM1 TENM4 ASTN2	1.68e-06	191	132	7	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK1 ABCC3 NEBL CYRIB PROM1 TENM4 ASTN2	1.68e-06	191	132	7	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B SEMA7A ACVRL1 PROM1 HMCN1 PTPRG CDH5	1.74e-06	192	132	7	9ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B SEMA7A ACVRL1 PROM1 HMCN1 PTPRG CDH5	1.74e-06	192	132	7	a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B SEMA7A ACVRL1 PROM1 HMCN1 PTPRG CDH5	1.74e-06	192	132	7	66defad13bd8e79319741e43ddb056841710b1d7
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A1 LAMA2 MOXD1 HMCN1 PTPRG SRGAP1 TNXB	1.80e-06	193	132	7	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	COL6A1 LAMA2 MOXD1 TENM4 HMCN1 VCAN SEPTIN11	1.86e-06	194	132	7	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEBL LAMA2 MOXD1 TENM4 HMCN1 SRGAP1 SEPTIN11	1.86e-06	194	132	7	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK1 FLNB ACVRL1 HMCN1 PTPRG CDH5 CCSER1	1.86e-06	194	132	7	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A1 UAP1 LAMA2 MOXD1 PTPRG SRGAP1 TNXB	1.92e-06	195	132	7	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	NEBL LAMA2 MOXD1 HMCN1 PTPRG SRGAP1 TNXB	1.92e-06	195	132	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UNC13B ABCC3 COL6A1 FLNA MOXD1 CHPF CDH5	1.99e-06	196	132	7	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 LAMA2 MOXD1 TENM4 HMCN1 VCAN TNXB	2.06e-06	197	132	7	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL6A1 LAMA2 MOXD1 HMCN1 SRGAP1 VCAN SEPTIN11	2.13e-06	198	132	7	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	356C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FLNB UAP1 LAMA2 MOXD1 VCAN SEPTIN11 TNXB	2.20e-06	199	132	7	beca4c7eb29ac771fd37f30cd23d4dce4afcfff8
ToppCell	356C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FLNB UAP1 LAMA2 MOXD1 VCAN SEPTIN11 TNXB	2.20e-06	199	132	7	cd3ab9a75b40e0d417d53b3d8756fc9bed30ac83
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A1 TMEM176B MOXD1 SRGAP1 VCAN SEPTIN11 TNXB	2.20e-06	199	132	7	38ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	UNC13B DOCK1 NEBL LAMA2 PTPRG SYNE2 CDH5	2.28e-06	200	132	7	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNB ACVRL1 HMCN1 PTPRG SYNE2 NKTR CDH5	2.28e-06	200	132	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLNB ACVRL1 HMCN1 PTPRG SYNE2 PLEC CDH5	2.28e-06	200	132	7	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 TMEM176B LAMA2 MOXD1 HMCN1 SRGAP1 TNXB	2.28e-06	200	132	7	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	UNC13B DOCK1 NEBL LAMA2 PTPRG SYNE2 CDH5	2.28e-06	200	132	7	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A1 LAMA2 MOXD1 HMCN1 VCAN SEPTIN11 CHPF	2.28e-06	200	132	7	4dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-4\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	COL6A1 LAMA2 MOXD1 HMCN1 VCAN SEPTIN11 CHPF	2.28e-06	200	132	7	bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	UNC13B DOCK1 NEBL LAMA2 PTPRG SYNE2 CDH5	2.28e-06	200	132	7	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A1 LAMA2 MOXD1 HMCN1 VCAN SEPTIN11 CHPF	2.28e-06	200	132	7	8256511b099c3eab8e33194f90c9ff354e7cfe8e
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNB ACVRL1 PTPRG SYNE2 NKTR CDH5 CCSER1	2.28e-06	200	132	7	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 LAMA2 MOXD1 HMCN1 SRGAP1 VCAN TNXB	2.28e-06	200	132	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 LAMA2 MOXD1 HMCN1 SRGAP1 VCAN TNXB	2.28e-06	200	132	7	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	UNC13B DOCK1 NEBL LAMA2 PTPRG SYNE2 CDH5	2.28e-06	200	132	7	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A1 LAMA2 MOXD1 HMCN1 SRGAP1 VCAN TNXB	2.28e-06	200	132	7	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Fibroblast\|World / shred by cell class for parenchyma	COL6A1 TMEM176B LAMA2 MOXD1 VCAN SEPTIN11 TNXB	2.28e-06	200	132	7	dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	UNC13B DOCK1 NEBL LAMA2 PTPRG SYNE2 CDH5	2.28e-06	200	132	7	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	UNC13B DOCK1 NEBL LAMA2 PTPRG SYNE2 CDH5	2.28e-06	200	132	7	7136936d05ab344a560cf159684c881063b5430d
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GRIN2B NEB SERPINA12 ABCC2 ATP12A EPHA5	8.94e-06	162	132	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 PROM1 PTPRG VCAN SYNE2 ASTN2	9.59e-06	164	132	6	1cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B CDHR1 NR1D1 PALS1 HMCN1 AMIGO3	1.26e-05	172	132	6	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B CDHR1 NR1D1 PALS1 HMCN1 AMIGO3	1.26e-05	172	132	6	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 GRIN2B HVCN1 SORCS1 HMCN1 EPHA5	1.39e-05	175	132	6	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	COL6A1 LAMA2 SORCS1 MOXD1 HMCN1 TNXB	1.43e-05	176	132	6	510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A1 OBSCN LAMA2 SORCS1 PTPRG VCAN	1.48e-05	177	132	6	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 LAMA2 SERPINA12 VCAN CHPF TNXB	1.73e-05	182	132	6	f4b74c2756989812abe4e7055ec8918f69d56025
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	ABCC3 BTNL8 PROM1 MUC5AC PADI1 CCSER1	1.79e-05	183	132	6	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	COL6A1 FLNC MOXD1 HMCN1 MOV10L1 CHPF	1.84e-05	184	132	6	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL6A1 UAP1 LAMA2 TENM4 VCAN TNXB	1.90e-05	185	132	6	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLNB SEMA7A ACVRL1 MTMR11 HMCN1 CDH5	2.08e-05	188	132	6	59f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB SEMA7A ACVRL1 MOXD1 PLEC CDH5	2.14e-05	189	132	6	feedac2751ed770f80bc56fec31662b5b3826f58
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 FLNC UAP1 LAMA2 VCAN TNXB	2.14e-05	189	132	6	0a8b827bba1efd885ad6c06929251c741dc3a541
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLNB SEMA7A ACVRL1 MOXD1 HMCN1 CDH5	2.14e-05	189	132	6	360f09f46231a83f99d8fa0158b72a38068e1642
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	COL6A1 FLNA NEBL LAMA2 VCAN SEPTIN11	2.14e-05	189	132	6	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FLNC NEBL OBSCN LAMA2 CYRIB CCSER1	2.21e-05	190	132	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	UNC13B BTNL8 LAMA2 ACVRL1 PTPRG CDH5	2.21e-05	190	132	6	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 LAMA2 NR1D1 VCAN CHPF TNXB	2.27e-05	191	132	6	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL6A1 UAP1 LAMA2 PTPRG VCAN TNXB	2.27e-05	191	132	6	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C APOB CEP350 PROM1 SAMD9L SYNE2	2.27e-05	191	132	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL6A1 LAMA2 MOXD1 HMCN1 PTPRG TNXB	2.27e-05	191	132	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 LAMA2 NR1D1 VCAN CHPF TNXB	2.34e-05	192	132	6	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A ACVRL1 PROM1 HMCN1 PTPRG CDH5	2.34e-05	192	132	6	9d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	POLR2A ARFGEF1 NLRP1 CLASP2 SYNE2 NKTR	2.34e-05	192	132	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL6A1 LAMA2 MOXD1 HMCN1 PTPRG TNXB	2.34e-05	192	132	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A ACVRL1 PROM1 HMCN1 PTPRG CDH5	2.34e-05	192	132	6	042391162df2e3d0027688dd14163c4c6821afe0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA7A ACVRL1 PROM1 HMCN1 PTPRG CDH5	2.34e-05	192	132	6	71b0bfee0461ff64cef35881db3959c517e9731b
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 LAMA2 NR1D1 VCAN CHPF TNXB	2.34e-05	192	132	6	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL ACSS1 NEB SYNE2 RPS6KA6 CCSER1	2.34e-05	192	132	6	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	367C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	BTNL8 ACVRL1 PTPRG BTNL3 CDH5 DISP1	2.41e-05	193	132	6	5c6b03d6d98aa873fda1a201d44a912246bb5a92
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEBL SEMA7A ACVRL1 PROM1 PTPRG CDH5	2.41e-05	193	132	6	e4b440d50ae7391b26924778be6d9d53e0692449
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEBL SEMA7A ACVRL1 PROM1 PTPRG CDH5	2.41e-05	193	132	6	e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 PROM1 SYNE2 ASTN2 ADGRA3 CCSER1	2.41e-05	193	132	6	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	droplet-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 LAMA2 MOXD1 VCAN CHPF DNAJA1	2.41e-05	193	132	6	2d891c00b8f0aace17d4c300b63e2341dcffa199
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 LAMA2 NR1D1 VCAN CHPF TNXB	2.41e-05	193	132	6	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL6A1 LAMA2 MOXD1 HMCN1 SRGAP1 TNXB	2.41e-05	193	132	6	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEBL SEMA7A ACVRL1 PROM1 PTPRG CDH5	2.41e-05	193	132	6	1772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCell	367C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	BTNL8 ACVRL1 PTPRG BTNL3 CDH5 DISP1	2.41e-05	193	132	6	d4b58eee97043b4337ec36c40f9af6499d864df9
ToppCell	Control-NK_CD56bright\|Control / Disease condition and Cell class	FLNB CDHR1 DOK7 HVCN1 ZNF667 SEPTIN11	2.41e-05	193	132	6	8b1e7a226a6057e1097c1525984127b54e823876
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SEMA7A MOXD1 TENM4 HMCN1 VCAN CDH5	2.41e-05	193	132	6	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A1 UAP1 LAMA2 VCAN CHPF TNXB	2.41e-05	193	132	6	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	COL6A1 LAMA2 MOXD1 HMCN1 PTPRG SRGAP1	2.41e-05	193	132	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A1 UAP1 LAMA2 VCAN CHPF TNXB	2.41e-05	193	132	6	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 PROM1 SYNE2 ASTN2 ADGRA3 CCSER1	2.41e-05	193	132	6	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
Computational	Genes in the cancer module 202.	FLNA FLNB ANK1 NEBL NEB	1.84e-06	28	81	5	MODULE_202
Drug	Deferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A	ABCC3 RPGRIP1L ITFG2 NEB TRIM14 ADCY7 PHKA2 NF2 NFKBIB	2.20e-06	196	132	9	3842_DN
Drug	Equilin [474-86-2]; Down 200; 15uM; HL60; HT_HG-U133A	RPGRIP1L POLM FRMPD1 NR1D1 TRIM14 FAAP100 NF2 CHPF PADI1	2.30e-06	197	132	9	3039_DN
Drug	Zardaverine [101975-10-4]; Down 200; 15uM; MCF7; HT_HG-U133A	ABCC3 FLNB NEBL CLASP2 GMEB2 CYRIB NF2 SEPTIN11 PLEC	2.30e-06	197	132	9	7347_DN
Drug	Domperidone maleate; Down 200; 7.4uM; PC3; HT_HG-U133A	ABCC3 ITFG2 FRMPD1 IREB2 NFKBIB SEPTIN11 ASTN1 ASTN2 MUC5AC	2.30e-06	197	132	9	4640_DN
Drug	C75; Down 200; 10uM; PC3; HT_HG-U133A	DOCK1 ITFG2 POLM IREB2 GMEB2 VPS13D ASTN2 TADA2A PADI1	2.30e-06	197	132	9	6428_DN
Drug	Glutethimide, para-amino [125-84-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A	ABCC3 COL6A1 LONP2 NR1D1 NF2 VCAN ZNF701 TOP3A FHIP2B	2.39e-06	198	132	9	7421_UP
Drug	CP-319743 [172078-87-4]; Down 200; 10uM; PC3; HT_HG-U133A	COL6A1 ITFG2 TRIM14 MOXD1 NF2 ZNF667 ASTN2 FHIP2B	1.80e-05	194	132	8	7537_DN
Drug	semustine; Down 200; 100uM; MCF7; HT_HG-U133A	DOCK1 NEBL ITFG2 NEB NR1D1 TRIM14 SLC25A12 TADA2A	1.87e-05	195	132	8	7540_DN
Drug	Fluspirilen [1841-19-6]; Down 200; 8.4uM; PC3; HT_HG-U133A	DOCK1 NEBL FAAP100 NF2 ASTN2 NKTR TADA2A MUC5AC	1.87e-05	195	132	8	6662_DN
Drug	Trapidil [15421-84-8]; Down 200; 19.4uM; HL60; HT_HG-U133A	NEB FAAP100 PHKA2 NF2 ABCC2 CHPF TOP3A PADI1	1.94e-05	196	132	8	3136_DN
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	DOCK1 COL6A1 SIN3B MTMR11 NF2 NFKBIB SEPTIN11 TADA2A	1.94e-05	196	132	8	3613_DN
Drug	Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A	NEBL NEB TRIM14 PHKA2 TENM4 NF2 ASTN2 TADA2A	2.01e-05	197	132	8	4091_DN
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A	FLNB LONP2 NR1D1 FAAP100 PHKA2 VPS13D NF2 HNRNPA0	2.01e-05	197	132	8	1640_DN
Drug	Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; PC3; HT_HG-U133A	ITFG2 POLM VPS13D VCAN NFKBIB SEPTIN11 ASTN2 TOP3A	2.01e-05	197	132	8	3768_DN
Drug	Phenelzine sulfate [156-51-4]; Up 200; 17uM; HL60; HT_HG-U133A	RPGRIP1L NEBL FRMPD1 NEB VCAN SEPTIN11 CHPF TOP3A	2.01e-05	197	132	8	2357_UP
Drug	Biotin [58-85-5]; Up 200; 16.4uM; HL60; HT_HG-U133A	NEBL FRMPD1 LAMA2 NLRP1 OCRL MEAK7 NF2 TADA2A	2.01e-05	197	132	8	2428_UP
Drug	Sulfabenzamide [127-71-9]; Down 200; 14.4uM; HL60; HT_HG-U133A	FLNB ITFG2 NLRP1 NEB PHKA2 HNRNPA0 NKTR CHPF	2.08e-05	198	132	8	2159_DN
Drug	Ribostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; MCF7; HT_HG-U133A	COL6A1 VPS13C POLR2A NR1D1 PHKA2 VCAN ZNF701 NKTR	2.08e-05	198	132	8	6765_UP
Drug	Monocrotaline [315-22-0]; Up 200; 12.2uM; PC3; HT_HG-U133A	ITFG2 NLRP1 GMEB2 MEAK7 VPS13D NF2 VCAN FHIP2B	2.08e-05	198	132	8	7127_UP
Drug	Griseofulvin [126-07-8]; Up 200; 11.2uM; HL60; HT_HG-U133A	COL6A1 NEBL NEB NR1D1 NF2 VCAN RPS6KA6 NKTR	2.08e-05	198	132	8	2332_UP
Drug	Halcinonide [3093-35-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A	CPLANE2 ANK1 POLM CDHR1 FRMPD1 GRIN2B SEPTIN11 NKTR	2.16e-05	199	132	8	6040_UP
Drug	Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A	RPGRIP1L NEBL SEMA7A FRMPD1 VPS13D TENM4 NF2 VCAN	2.16e-05	199	132	8	4774_UP
Drug	Thiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ABCC3 ITFG2 VPS13C PHKA2 TENM4 NF2 BTNL3 VCAN	2.24e-05	200	132	8	2894_UP
Drug	Nialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A	ITFG2 IREB2 NR1D1 FAAP100 VPS13D MTMR11 NF2 ASTN2	2.24e-05	200	132	8	4525_DN
Drug	mitoxantrone	ABCC3 POLR2A ACVRL1 ADCY7 PREB ABCC2 TOP3A	3.28e-05	154	132	7	CID000004212
Drug	5(6)-carboxy-2',7'-dichlorofluorescein	ABCC3 ABCC2	3.34e-05	2	132	2	ctd:C053897
Drug	E3040 glucuronide	ABCC3 ABCC2	3.34e-05	2	132	2	CID000443294
Drug	celastrol; Up 200; 2.5uM; MCF7; HT_HG-U133A_EA	ABCC3 RPGRIP1L ITFG2 NR1D1 ADCY7 USPL1 DNAJA1	6.39e-05	171	132	7	887_UP
Drug	PTBD	ABCC3 PLEC ABCC2	8.24e-05	15	132	3	CID000197408
Drug	E3040 sulfate	ABCC3 ABCC2	9.97e-05	3	132	2	CID000443293
Drug	5-carboxyfluorescein diacetate	ABCC3 ABCC2	9.97e-05	3	132	2	ctd:C084577
Drug	Monobenzone [103-16-2]; Down 200; 20uM; MCF7; HT_HG-U133A	SEMA7A ITFG2 LONP2 POLM CEP350 VPS13D NF2	1.08e-04	186	132	7	3391_DN
Drug	NSC91998	ABCC3 MAP6 ACVRL1 ABCC2 TOP3A	1.09e-04	81	132	5	CID000005668
Drug	Ganciclovir [82410-32-0]; Down 200; 15.6uM; MCF7; HT_HG-U133A	CYRIB VPS13D HNRNPA0 SEPTIN11 ZNF701 PLEC TOP3A	1.12e-04	187	132	7	3368_DN
Drug	Iohexol [66108-95-0]; Down 200; 4.8uM; HL60; HT_HG-U133A	FLNB ITFG2 TRIM14 CYRIB VPS13D HNRNPA0 PLEC	1.16e-04	188	132	7	2461_DN
Drug	Fenbendazole [43210-67-9]; Down 200; 13.4uM; MCF7; HT_HG-U133A	ITFG2 POLM CYRIB VPS13D NF2 TADA2A PLEC	1.28e-04	191	132	7	3888_DN
Drug	Pindolol [13523-86-9]; Down 200; 16.2uM; PC3; HT_HG-U133A	COL6A1 ITFG2 NEB NF2 ZNF667 RPS6KA6 TOP3A	1.32e-04	192	132	7	4496_DN
Drug	amsacrine	ABCC3 ACVRL1 ABCC2 TOP3A	1.34e-04	45	132	4	CID000002179
Drug	Fluvastatin sodium salt [93957-55-2]; Down 200; 9.2uM; PC3; HT_HG-U133A	ITFG2 FAAP100 NF2 VCAN ZNF667 CHPF TOP3A	1.36e-04	193	132	7	6691_DN
Drug	Imipramine hydrochloride [113-52-0]; Down 200; 12.6uM; MCF7; HT_HG-U133A	DOCK1 ITFG2 CLASP2 NR1D1 VPS13D ZNF701 NKTR	1.36e-04	193	132	7	5440_DN
Drug	Isradipine [75695-93-1]; Down 200; 10.8uM; PC3; HT_HG-U133A	NEBL IREB2 OCRL MEAK7 MOXD1 PHF11 NKTR	1.41e-04	194	132	7	6347_DN
Drug	Ungerine nitrate; Down 200; 10.2uM; MCF7; HT_HG-U133A	COL6A1 ITFG2 TRIM14 CYRIB PHKA2 VPS13D NF2	1.41e-04	194	132	7	6076_DN
Drug	Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT_HG-U133A	NEBL ITFG2 NEB NF2 NFKBIB TADA2A MUC5AC	1.41e-04	194	132	7	3166_DN
Drug	Thiocolchicoside [602-41-5]; Down 200; 7uM; MCF7; HT_HG-U133A	NEBL ARFGEF1 OCRL NEB NF2 ASTN2 CHPF	1.45e-04	195	132	7	5520_DN
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; HL60; HG-U133A	LONP2 POLR2A CLASP2 PHKA2 VPS13D SLC25A12 FHIP2B	1.45e-04	195	132	7	2017_DN
Drug	Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; HL60; HT_HG-U133A	FLNB POLM POLR2A NLRP1 SCAP NKTR TADA2A	1.45e-04	195	132	7	2942_UP
Drug	Calycanthine [595-05-1]; Down 200; 11.6uM; PC3; HT_HG-U133A	ABCC3 COL6A1 NEBL TRIM14 VPS13D VCAN NFKBIB	1.45e-04	195	132	7	5744_DN
Drug	Loracarbef [121961-22-6]; Up 200; 10.8uM; HL60; HT_HG-U133A	UNC13B COL6A1 FLNB POLM SEPTIN11 PLEC FHIP2B	1.45e-04	195	132	7	2970_UP
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A	COL6A1 VPS13D NF2 NFKBIB SEPTIN11 TADA2A PADI1	1.45e-04	195	132	7	3755_DN
Drug	3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A	CPLANE2 COL6A1 NEBL LONP2 TRIM14 VPS13D TOP3A	1.45e-04	195	132	7	7361_UP
Drug	Enoxacin [74011-58-8]; Down 200; 12.4uM; HL60; HG-U133A	UNC13B SIN3B ITFG2 POLR2A VPS13D TOP3A PADI1	1.50e-04	196	132	7	1597_DN
Drug	Tracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; PC3; HT_HG-U133A	POLM NR1D1 MEAK7 NF2 VCAN SEPTIN11 EPHA5	1.50e-04	196	132	7	6619_DN
Drug	Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; HL60; HT_HG-U133A	LAMA2 NLRP1 ACVRL1 NR1D1 TRIM14 NF2 NFKBIB	1.50e-04	196	132	7	2939_UP
Drug	Dimethadione [695-53-4]; Down 200; 31uM; HL60; HT_HG-U133A	NLRP1 TRIM14 VPS13D NF2 RPS6KA6 SEPTIN11 CHPF	1.50e-04	196	132	7	3029_DN
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; PC3; HT_HG-U133A	SEMA7A CDHR1 ADCY7 ABCC2 MYO15A DNAJA1 PCDHB1	1.50e-04	196	132	7	4443_UP
Drug	estradiol, USP; Down 200; 0.01uM; PC3; HT_HG-U133A	NEBL LAMA2 VPS13D BTNL3 NFKBIB ABCC2 TOP3A	1.50e-04	196	132	7	4465_DN
Drug	Prostaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A	DOCK1 GMEB2 NR1D1 CEP350 NF2 MYO15A PADI1	1.50e-04	196	132	7	6571_DN
Drug	Cromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; PC3; HT_HG-U133A	DOCK1 ZNF136 ITFG2 PHKA2 MOXD1 VPS13D NFKBIB	1.50e-04	196	132	7	5754_DN
Drug	Proxyphylline [603-00-9]; Up 200; 16.8uM; HL60; HT_HG-U133A	NEBL VPS13C NF2 BTNL3 NFKBIB ATP12A PCDHB1	1.50e-04	196	132	7	3115_UP
Drug	Pinacidil [85371-64-8]; Down 200; 16.4uM; HL60; HT_HG-U133A	FLNB ITFG2 ARFGEF1 VPS13D VCAN NFKBIB SEPTIN11	1.50e-04	196	132	7	2406_DN
Drug	Clioquinol [130-26-7]; Down 200; 13uM; PC3; HT_HG-U133A	ITFG2 NF2 VCAN HNRNPA0 TADA2A CHPF PADI1	1.50e-04	196	132	7	4663_DN
Drug	Clozapine [5786-21-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ITFG2 VPS13C TRIM14 KIFAP3 PHKA2 NF2 NFKBIB	1.55e-04	197	132	7	2644_DN
Drug	clozapine; Up 200; 10uM; MCF7; HT_HG-U133A	NEBL IREB2 NEB ZNF701 NKTR TADA2A PLEC	1.55e-04	197	132	7	6988_UP
Drug	Fluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A	LONP2 FAAP100 CYRIB NF2 ZNF701 TADA2A PLEC	1.55e-04	197	132	7	5356_DN
Drug	Gibberellic acid [77-06-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A	CPLANE2 ABCC3 FLNC POLM NF2 VCAN TOP3A	1.55e-04	197	132	7	4818_UP
Drug	aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A_EA	ABCC3 NEBL ITFG2 LONP2 MEAK7 TADA2A TOP3A	1.55e-04	197	132	7	1042_UP
Drug	PF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A	COL6A1 NEBL TRIM14 FAAP100 PLEC ATP12A EPHA5	1.55e-04	197	132	7	5939_DN
Drug	2-Chloropyrazine [14508-49-7]; Up 200; 35uM; PC3; HT_HG-U133A	TMEM176B LAMA2 NLRP1 GRIN2B VPS13D NFKBIB TADA2A	1.55e-04	197	132	7	5750_UP
Drug	Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; PC3; HT_HG-U133A	COL6A1 ITFG2 NR1D1 FAAP100 VPS13D NFKBIB ABCC2	1.59e-04	198	132	7	3730_DN
Drug	Sulfathiazole [72-14-0]; Up 200; 15.6uM; PC3; HT_HG-U133A	ABCC3 NLRP1 FAAP100 NF2 BTNL3 ABCC2 PCDHB1	1.59e-04	198	132	7	4183_UP
Drug	vinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A	ITFG2 LONP2 VPS13D VCAN TADA2A MUC5AC PADI1	1.59e-04	198	132	7	7517_DN
Drug	Amoxapine [14028-44-5]; Up 200; 12.8uM; HL60; HG-U133A	NEBL GMEB2 ACVRL1 MOXD1 VPS13D TADA2A PLEC	1.59e-04	198	132	7	2013_UP
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A	CPLANE2 COL6A1 ITFG2 FRMPD1 NLRP1 MUC5AC PCDHB1	1.59e-04	198	132	7	2760_UP
Drug	Tridihexethyl chloride; Down 200; 11.4uM; PC3; HT_HG-U133A	NF2 VCAN ZNF667 ASTN2 TADA2A TOP3A FHIP2B	1.59e-04	198	132	7	5067_DN
Drug	Doxepin hydrochloride [1229-29-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	SIN3B POLR2A TRIM14 CYRIB HNRNPA0 ASTN2 TOP3A	1.59e-04	198	132	7	7415_DN
Drug	Gramine [87-52-5]; Down 200; 23uM; MCF7; HT_HG-U133A	ITFG2 NEB CYRIB PHKA2 VPS13D NF2 NFKBIB	1.59e-04	198	132	7	2799_DN
Drug	Nitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A	COL6A1 NEBL ITFG2 FAAP100 CYRIB NKTR TOP3A	1.59e-04	198	132	7	2303_DN
Drug	Nadolol [42200-33-9]; Down 200; 13uM; PC3; HT_HG-U133A	NEBL FRMPD1 TRIM14 NF2 VCAN ASTN1 ASTN2	1.59e-04	198	132	7	4021_DN
Drug	Chlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A	ITFG2 NR1D1 TRIM14 CYRIB PHKA2 NF2 TOP3A	1.59e-04	198	132	7	2217_DN
Drug	Gly-His-Lys acetate salt; Up 200; 1uM; PC3; HT_HG-U133A	POLM NLRP1 OCRL CYRIB KIFAP3 VCAN EPHA5	1.59e-04	198	132	7	6560_UP
Drug	Sulfadoxine [2447-57-6]; Down 200; 12.8uM; PC3; HT_HG-U133A	COL6A1 IREB2 NR1D1 TRIM14 MEAK7 SEPTIN11 FHIP2B	1.59e-04	198	132	7	5852_DN
Drug	Sulfisoxazole [127-69-5]; Down 200; 15uM; PC3; HT_HG-U133A	NEBL FRMPD1 VPS13D NF2 VCAN SEPTIN11 TOP3A	1.59e-04	198	132	7	4661_DN
Drug	Rolipram [61413-54-5]; Down 200; 14.6uM; HL60; HT_HG-U133A	UNC13B FLNB NLRP1 VPS13D ZNF667 ABCC2 TOP3A	1.59e-04	198	132	7	3072_DN
Drug	Bethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A	ZNF136 NEB NR1D1 TRIM14 NF2 NFKBIB SEPTIN11	1.59e-04	198	132	7	3537_UP
Drug	S(-)Eticlopride hydrochloride [97612-24-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A	ABCC3 COL6A1 RPGRIP1L ANK1 GRIN2B ZNF701 MUC5AC	1.59e-04	198	132	7	3393_UP
Drug	Dicloxacillin sodium salt [13412-64-1]; Down 200; 8.2uM; MCF7; HT_HG-U133A	ITFG2 NF2 SEPTIN11 TADA2A MUC5AC TOP3A PADI1	1.64e-04	199	132	7	3307_DN
Drug	Oleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HT_HG-U133A	COL6A1 IREB2 MOXD1 VPS13D NFKBIB SEPTIN11 ASTN1	1.64e-04	199	132	7	4615_DN
Drug	Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; PC3; HT_HG-U133A	CYRIB MOXD1 SEPTIN11 CHPF TOP3A PADI1 EPHA5	1.64e-04	199	132	7	6355_DN
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	COL6A1 NEBL TRIM14 KIFAP3 MTMR11 ASTN2 NKTR	1.64e-04	199	132	7	5535_DN
Drug	Rilmenidine hemifumarate [54187-04-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	COL6A1 RPGRIP1L NEBL VPS13D NFKBIB PLEC PADI1	1.70e-04	200	132	7	6512_DN
Drug	SB 203580; Up 200; 1uM; MCF7; HT_HG-U133A	ITFG2 NR1D1 MEAK7 ADCY7 NF2 SEPTIN11 TADA2A	1.70e-04	200	132	7	6899_UP
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A	RPGRIP1L ITFG2 VPS13D NF2 ASTN2 TADA2A TOP3A	1.70e-04	200	132	7	5212_DN
Drug	Oxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; PC3; HT_HG-U133A	COL6A1 ITFG2 TRIM14 VPS13D VCAN SEPTIN11 TOP3A	1.70e-04	200	132	7	5772_DN
Drug	Pluronic	ABCC3 APOB PROM1 VCAN ABCC2	1.80e-04	90	132	5	CID000024751
Drug	macitentan	ABCC3 ABCC2	1.99e-04	4	132	2	ctd:C533860
Drug	BFNU	IREB2 VCAN	1.99e-04	4	132	2	CID000096886
Drug	lovastatin acid	ABCC3 SYNE2 ABCC2	2.02e-04	20	132	3	CID000064727
Drug	daunorubicin semiquinone	ABCC3 ZFP90 POLM ACVRL1 ATAD2 PREB ABCC2 TOP3A	2.64e-04	285	132	8	CID000002958
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB FLNC	7.60e-08	3	126	3	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB FLNC	7.60e-08	3	126	3	DOID:0111190 (implicated_via_orthology)
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13C VPS13D	5.41e-05	3	126	2	DOID:0111611 (implicated_via_orthology)
Disease	Congenital muscular dystrophy (disorder)	LAMA2 SYNE2	2.68e-04	6	126	2	C0699743
Disease	bilirubin metabolic disorder (biomarker_via_orthology)	ABCC3 ABCC2	3.75e-04	7	126	2	DOID:2741 (biomarker_via_orthology)
Disease	fatty liver disease (biomarker_via_orthology)	ABCC3 APOB ABCC2	3.78e-04	33	126	3	DOID:9452 (biomarker_via_orthology)
Disease	Muscular Dystrophy	COL6A1 LAMA2	4.98e-04	8	126	2	C0026850
Disease	common bile duct neoplasm (is_marker_for)	APOB MUC5AC	4.98e-04	8	126	2	DOID:4608 (is_marker_for)
Disease	asparaginase-induced acute pancreatitis	NEB ZNF701	6.39e-04	9	126	2	EFO_1001507
Disease	sphingolipid measurement	DOK7 SYNE2 ANKRD30A	6.69e-04	40	126	3	EFO_0004622
Disease	Malignant neoplasm of breast	FLNA FLNB ANK1 FRMPD1 OBSCN LAMA2 SORCS1 NF2 ZNF436 SYNE2 ANKRD30A ASTN2 CDH5	7.00e-04	1074	126	13	C0006142
Disease	clinical treatment	APOB GRIN2B ADCY7	7.20e-04	41	126	3	EFO_0007056
Disease	glycerophosphorylcholine measurement	GRIN2B CCSER1	9.70e-04	11	126	2	EFO_0020018
Disease	myopathy (implicated_via_orthology)	FLNA FLNB FLNC	1.14e-03	48	126	3	DOID:423 (implicated_via_orthology)
Disease	intracranial aneurysm (is_implicated_in)	COL22A1 VCAN	1.16e-03	12	126	2	DOID:10941 (is_implicated_in)
Disease	Congenital muscular dystrophy	COL6A1 LAMA2	1.16e-03	12	126	2	cv:C0699743
Disease	glycochenodeoxycholate glucuronide (1) measurement	ABCC3 ABCC2	1.37e-03	13	126	2	EFO_0800474
Disease	X-24588 measurement	ABCC3 ABCC2	1.37e-03	13	126	2	EFO_0800898
Disease	refractive error, age at onset, Myopia	COL6A1 POLR2A LAMA2 GRIN2B SLC25A12	1.46e-03	193	126	5	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Familial thoracic aortic aneurysm and aortic dissection	FLNA ACVRL1 VCAN	1.52e-03	53	126	3	C4707243
Disease	Disorder of eye	RPGRIP1L CDHR1 PROM1 PHYH VCAN	2.21e-03	212	126	5	C0015397
Disease	FEV/FEC ratio	NEBL VPS13C IREB2 NEB MEAK7 MTMR11 DNAH12 HMCN1 SBF2 SYNE2 ASTN2 MYO15A TNXB	2.32e-03	1228	126	13	EFO_0004713
Disease	X-21441 measurement	ABCC3 ABCC2	2.36e-03	17	126	2	EFO_0800814
Disease	osteochondrodysplasia (is_implicated_in)	FLNA FLNB	2.95e-03	19	126	2	DOID:2256 (is_implicated_in)
Disease	response to supplemental oxygen	SERPINA12 ASTN2	2.95e-03	19	126	2	EFO_0009796
Disease	level of Sterol ester (27:1/20:3) in blood serum	DOK7 NOMO1	2.95e-03	19	126	2	OBA_2045199
Disease	bilirubin measurement	ANK1 APOB MEAK7 CYRIB SCAP ASTN2 ABCC2	2.96e-03	442	126	7	EFO_0004570
Disease	Colorectal Carcinoma	UNC13B ABCC3 FLNC OBSCN ARFGEF1 APOB PROM1 ABCC2 CDH5	3.24e-03	702	126	9	C0009402
Disease	epilepsy (biomarker_via_orthology)	GRIN2B NF2	3.60e-03	21	126	2	DOID:1826 (biomarker_via_orthology)
Disease	treatment resistant depression, response to antidepressant	WDR64 CCSER1	3.60e-03	21	126	2	EFO_0009854, GO_0036276
Disease	coronary atherosclerosis measurement, traffic air pollution measurement	DOCK1 NEBL	3.60e-03	21	126	2	EFO_0007908, EFO_0007938

Protein segments in the cluster

Peptide	Gene	Start	Entry
LKGVVHHEKETFLDP	PTPRG	221	P23470
HAVEVTLDPETAHPK	BTNL3	286	Q6UXE8
ALTHKLVFDHQPGDI	ACSS1	316	Q9NUB1
DEHHFVAVALRKPDG	AASDHPPT	236	Q9NRN7
EDIPAGSIIFKVHAV	CDHR1	146	Q96JP9
DHLDGDVFHLTVPSK	VCAN	246	P13611
HAVEVTLDPETAHPK	BTNL8	286	Q6UX41
LTKIDGVNVDTHHIP	ADGRA3	671	Q8IWK6
TGHIVTLVFEKHFPA	ARFGEF1	1301	Q9Y6D6
AQEGHVPVADVLIKH	ANK1	676	P16157
LHVIFGGTKVVQHIP	ATP13A1	381	Q9HD20
FDHPNIIHLEGVVTK	EPHA5	731	P54756
HGAVIEVHNKASLTP	ANKRD30A	161	Q9BXX3
HEAPKFTVETLEHTV	BTBD11	341	A6QL63
AHLHVEIFGTQGKPA	ACVRL1	311	P37023
IKPDGRVLHDTHAVV	ADAD1	261	Q96M93
GSHLAPAVIHALEKF	ATAD2	806	Q6PL18
KAIAEHVKGIHPISD	CCSER1	401	Q9C0I3
NVLPAHVAAHFIGDK	ADCY7	851	P51828
RKASVHKHVVFLEPG	AMIGO3	446	Q86WK7
VITSHPGQIVKHGDI	DNAJA1	286	P31689
GQFDREHTKVHFLPV	CDH5	541	P33151
KATHQAVEGFVHPIT	DISP1	1316	Q96F81
KITLHVPEHLIADGS	ASTN1	411	O14525
VKVTLHVPEHFIADG	ASTN2	461	O75129
LQGHDVDFLITHPKE	POLM	326	Q9NP87
DEHVISPKEFVHLAG	GMEB2	121	Q9UKD1
FTVEHDSLKIEPVFH	NOMO3	311	P69849
VGVEAHVDIHSDVPK	PADI1	21	Q9ULC6
PVDNVTLKHLEHTGF	IREB2	386	P48200
AKHIFDHVIGPEGVL	ABCC3	786	O15438
PKSGTAHIHVVVLDV	PCDHB1	221	Q9Y5F3
FTVEHDSLKIEPVFH	NOMO2	311	Q5JPE7
TDIHLHFPAGAVTKD	LONP2	726	Q86WA8
ALEHVIHLGVKVLFP	MOV10L1	646	Q9BXT6
PIHQDELLAHTGKEF	MAGEE2	331	Q8TD90
VVPEHAKVHDSAVVA	MAP6	686	Q96JE9
IFELTDHQKHPAGTI	RPGRIP1L	896	Q68CZ1
GSLHKFIPEEILIHG	MTMR11	121	A4FU01
PFIIGVHSVFKTDVH	SBF2	271	Q86WG5
AEPVIHFHKTAFLGQ	SBF2	381	Q86WG5
EDPALLAFHKGDIIH	MYO15A	2881	Q9UKN7
DSAGCHLFVVEKVHP	IBTK	611	Q9P2D0
KPVEIFHIIEHFCLG	METTL14	326	Q9HCE5
KTPIAIEIEHFVHIV	ATP12A	296	P54707
VVEVAHPKIIHESGA	ASPDH	71	A6ND91
FHHKFEILDAVVVVV	HVCN1	166	Q96D96
LKGEDSVPDTVHHVV	DDX1	431	Q92499
EGHTPLHVAVIHKDV	NFKBIB	206	Q15653
RFIPHENGVHTIDVK	FLNB	2346	O75369
HEDVFPGHFILKVSA	FAT2	3021	Q9NYQ8
FEELLQKPHEGIIHS	FHIP2B	456	Q86V87
AEPGAVEAVHLPHFV	NLRP1	1156	Q9C000
SDKHTIRFIPHENGV	FLNC	2461	Q14315
FTVEHDSLKIEPVFH	NOMO1	311	Q15155
HPEIFGLHENVDISK	DNAH12	2771	Q6ZR08
TTKGIVFQHPEIVAH	LAMA2	1206	P24043
DPLSAVDAHVGKHIF	ABCC2	786	Q92887
CHDEGVVKEIPITHH	RPS6KA6	46	Q9UK32
FPHHGTFEVIKNTDL	MED17	216	Q9NVC6
AKSHPEVSIEHLGQV	MUC5AC	3571	P98088
PCVAVLEDHDKHVFG	MEAK7	291	Q6P9B6
HHLEEPVIFIGALKT	FAAP100	276	Q0VG06
HHETLIGEEQRPVFK	ITFG2	106	Q969R8
AGDHKKEFEVTVHVP	HMCN1	1811	Q96RW7
VLDHDVSKEEPVTFH	NF2	81	P35240
HLHITEPKGVFAKEQ	OBSCN	1156	Q5VST9
GKAVQVDPHHILIED	OBSCN	6051	Q5VST9
PPAKETVIHVKAHFD	PALS1	341	Q8N3R9
HQKHVFVLSEAGKPV	MON1A	251	Q86VX9
AVREVVEFAKHIPGF	NR1D1	446	P20393
LVAKLAGLEVPVVHH	CPLANE2	71	Q9BU20
HVKHFVINLIGDFEV	APOB	2316	P04114
IHGDKVTEALRPFHE	DOCK1	1581	Q14185
HLGVKVFSVAITPDH	COL6A1	181	P12109
HVGISFVPKETGEHL	FLNA	2006	P21333
PVKVHFAEEVLISGH	FRMPD1	156	Q5SYB0
EHVGILHKDFESILP	CEP350	766	Q5VT06
EEIASEPKSAHVFHV	COL22A1	186	Q8NFW1
HVHPVGAFAKTSKID	CYRIB	266	Q9NUQ9
VHRFHVTVAPGTKLE	DOK7	111	Q18PE1
LVHVHFKEEIGVAEL	SCAP	271	Q12770
GNIDVHPSEKALIVH	KIFAP3	16	Q92845
HGGRKSVIHVLPDEV	PHKA2	221	P46019
VHLVMEKGDTVFFHP	PHYH	246	O14832
EKGDTVFFHPLLIHG	PHYH	251	O14832
IIIHHETIFPDAKEL	SRGAP1	686	Q7Z6B7
HLPFAVVGSTEEVKI	SEPTIN11	231	Q9NVA2
FSPEEHLKHGEVILE	SYNE2	3921	Q8WXH0
VGPVEHDKFIESHAL	TADA2A	261	O75478
LPAEVKAIGTEHDHV	LRRC28	256	Q86X40
TTKPAPHLDGVHVVF	NKTR	126	P30414
DLIHEIAFPGKHFQE	RPL7L1	196	Q6DKI1
TIHFGVKDKPHGEIV	SAMD9L	236	Q8IVG5
SHKAGPIGILFELVH	PROM1	46	O43490
KEVRKVHFDTQEHGP	PPP1R32	126	Q7Z5V6
SAGHEKLPVHVEDAL	SIN3B	31	O75182
PVSALFHIGVKVVDE	OCRL	526	Q01968
VIAAGAGAIVHEKHP	TMEM176B	106	Q3YBM2
IFEEHGDLTKIAPHR	SERPINA12	331	Q8IW75
QGIHSDVVFVVHGKP	ABTB1	111	Q969K4
VKEIFGQTIIHHHIP	SLC25A12	111	O75746
RVAHADVFAPVKAHV	CHPF	556	Q8IZ52
AVHAVIGDELKPHLS	CLASP2	1246	O75122
FVVHKRIHAGEKIPE	ZNF667	296	Q5HYK9
AHGIVVTDVAFLPEK	PREB	341	Q9HCU5
LIDHQRTHTGEKPFV	ZNF567	296	Q8N184
RHKKFEVPASEIHIV	USPL1	481	Q5W0Q7
PVTDLLVHKEVHTGI	ZNF436	121	Q9C0F3
SFQVHERIHTGEKPF	ZNF136	266	P52737
KVEPVIQRGHESLVH	MOXD1	221	Q6UVY6
EKPSGIHVFAVLLHA	MOXD1	376	Q6UVY6
AVVKFHPIQGHRVEV	HNRNPA0	156	Q13151
GHIELAKPVFHVGFL	POLR2A	86	P24928
SDLVVHQRIHTGEKP	ZNF672	296	Q499Z4
KHVGPVHVEALTVPE	TNXB	1956	P22105
IRPFFHALSVKHEDV	TXNDC2	486	Q86VQ3
PEHVVKVVGGHVLYV	ZBTB4	296	Q9P1Z0
PGIDHFLLSKVAIHA	TENM4	1451	Q6N022
IHKVVEPGEQEHSFA	SEMA7A	436	O75326
VPQTGFHHEKSDLLI	VPS13C	701	Q709C8
QVDLFTHPGTGEHKV	UNC13B	1426	O14795
VELAHFVGSDAPKVH	UBQLNL	146	Q8IYU4
EEHGRHTDATVKVPF	PHF11	206	Q9UIL8
VHEAVKAGVVGPELH	PLEC	3546	Q15149
KEFHAPLIIDENGVH	UAP1	501	Q16222
AFVPEIFHRIKVTHD	TOP3A	261	Q13472
HPVGLALEAAVHVQK	TRIM14	56	Q14142
EVHIFHPEGKIGNQV	ZNF701	216	Q9NV72
FELKPGVRVLVHAAH	SORCS1	1071	Q8WY21
LDEHIRVHTGEKPFS	ZNF425	401	Q6IV72
LVQHERTHTGEKPFE	ZFP90	381	Q8TF47
DVVPFLQDGKHAVHL	WDR64	596	B1ANS9
AFLVEHQRIHTGEKP	ZNF527	371	Q8NB42
KHVQDIDVGPTHVVE	VPS13D	836	Q5THJ4
IDVGPTHVVEKFNVH	VPS13D	841	Q5THJ4
VSDAAYKGVHPHIVE	NEBL	816	O76041
KDDFHHLSVVPRVEL	GRIN2B	56	Q13224
HIGFRSLEDDPKLVH	NEB	1831	P20929