Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhypotaurine monooxygenase activity

FMO1 FMO2

4.51e-055432GO:0047822
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

4.51e-055432GO:0140444
GeneOntologyMolecularFunctionN,N-dimethylaniline monooxygenase activity

FMO1 FMO2

6.76e-056432GO:0004499
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

SUN3 SYNE1 SYNE2

1.24e-0445433GO:0043495
GeneOntologyMolecularFunctionNADP binding

CAT FMO1 FMO2

3.22e-0462433GO:0050661
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SUN3 SYNE1 SYNE2

1.23e-0611423GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SUN3 SYNE1 SYNE2

1.23e-0611423GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SUN3 SYNE1 SYNE2

1.23e-0611423GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SUN3 SYNE1 SYNE2

1.23e-0611423GO:0106094
DomainSpectrin/alpha-actinin

EVPL EVPLL SYNE1 SYNE2

8.36e-0732434IPR018159
DomainSPEC

EVPL EVPLL SYNE1 SYNE2

8.36e-0732434SM00150
DomainEnvoplakin

EVPL EVPLL

5.18e-062432IPR030460
DomainKASH

SYNE1 SYNE2

3.10e-054432PF10541
DomainKASH

SYNE1 SYNE2

3.10e-054432IPR012315
DomainKASH

SYNE1 SYNE2

3.10e-054432SM01249
DomainKASH

SYNE1 SYNE2

3.10e-054432PS51049
DomainSpectrin_repeat

EVPL SYNE1 SYNE2

3.98e-0529433IPR002017
DomainFMO-like

FMO1 FMO2

5.15e-055432PF00743
DomainFlavin_mOase-like

FMO1 FMO2

5.15e-055432IPR020946
DomainFlavin_mOase

FMO1 FMO2

5.15e-055432IPR000960
DomainDiMe-aniline_mOase

FMO1 FMO2

5.15e-055432IPR012143
DomainActinin_actin-bd_CS

SYNE1 SYNE2

1.27e-0323432IPR001589
DomainACTININ_2

SYNE1 SYNE2

1.27e-0323432PS00020
DomainACTININ_1

SYNE1 SYNE2

1.27e-0323432PS00019
DomainSpectrin

SYNE1 SYNE2

1.27e-0323432PF00435
Domain-

FMO1 FMO2

7.37e-03564323.50.50.60
DomainFAD/NAD-binding_dom

FMO1 FMO2

7.63e-0357432IPR023753
PathwayWP_CATALYTIC_CYCLE_OF_MAMMALIAN_FLAVINCONTAINING_MONOOXYGENASES_FMOS

FMO1 FMO2

5.96e-055352M39449
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

1.56e-06244222768332
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

1.56e-06244217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

1.56e-06244231578382
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

1.56e-06244211792814
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

1.56e-06244224931616
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

1.56e-06244217267447
Pubmed

RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors.

CSNK1G3 IPMK

1.56e-06244216247451
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

1.56e-06244224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

1.56e-06244224586179
Pubmed

Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.

FMO1 FMO2

1.56e-06244215144220
Pubmed

Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.

ATG5 OPTN

4.69e-06344225398946
Pubmed

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.

SYNE1 SYNE2

4.69e-06344217462627
Pubmed

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.

SYNE1 SYNE2

4.69e-06344210878022
Pubmed

Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes.

FMO1 FMO2

4.69e-06344230381441
Pubmed

The phenotype of a flavin-containing monooyxgenase knockout mouse implicates the drug-metabolizing enzyme FMO1 as a novel regulator of energy balance.

FMO1 FMO2

4.69e-06344224792439
Pubmed

Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.

SYNE1 SYNE2

4.69e-06344233472039
Pubmed

Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.

SYNE1 SYNE2

4.69e-06344225516977
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE1 SYNE2

4.69e-06344216079285
Pubmed

Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine.

FMO1 FMO2

4.69e-06344219262426
Pubmed

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

SYNE1 SYNE2

4.69e-06344212408964
Pubmed

Mammalian sperm head formation involves different polarization of two novel LINC complexes.

SUN3 SYNE1

9.37e-06444220711465
Pubmed

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.

SYNE1 SYNE2

9.37e-06444219596800
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE1 SYNE2

9.37e-06444216648470
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE1 SYNE2

9.37e-06444223071752
Pubmed

Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.

SYNE1 SYNE2

9.37e-06444228716842
Pubmed

Quantitative analysis of FMO gene mRNA levels in human tissues.

FMO1 FMO2

9.37e-06444216183778
Pubmed

The molecular biology of the flavin-containing monooxygenases of man.

FMO1 FMO2

9.37e-0644427720101
Pubmed

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

SYNE1 SYNE2

9.37e-06444220108321
Pubmed

The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression.

FMO1 FMO2

1.56e-0554428128486
Pubmed

Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine.

FMO1 FMO2

1.56e-05544232156684
Pubmed

A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.

FMO1 FMO2

1.56e-0554428311461
Pubmed

Mechanism of cargo-directed Atg8 conjugation during selective autophagy.

ATG5 OPTN

1.56e-05544227879200
Pubmed

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

SYNE1 SYNE2

1.56e-05544218396275
Pubmed

LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.

SYNE1 SYNE2

1.56e-05544222632968
Pubmed

Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein.

ATG5 OPTN

1.56e-05544229133525
Pubmed

High frequency of alternative splicing of human genes participating in the HIV-1 life cycle: a model using TSG101, betaTrCP, PPIA, INI1, NAF1, and PML.

SMARCB1 TNIP1

2.34e-05644214526201
Pubmed

Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans.

FMO1 FMO2

2.34e-05644212527699
Pubmed

Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.

SYNE1 SYNE2

2.34e-05644233058875
Pubmed

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.

SYNE1 SYNE2

2.34e-05644218827015
Pubmed

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins.

TNIP1 OPTN

3.27e-05744218212736
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CAT POLR1A AARS2 TRRAP SYNE1 GOLGB1 SYNE2 CEP290

3.80e-05102444824711643
Pubmed

Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.

SYNE1 SYNE2

6.99e-051044228533284
Pubmed

Nuclear membrane proteins with potential disease links found by subtractive proteomics.

SYNE1 SYNE2

6.99e-051044212958361
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

FMO1 FMO2 UGT1A10

8.18e-056644319898482
Pubmed

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus.

ATG5 TNIP1

8.54e-051144221068098
Pubmed

A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.

SYNE1 SYNE2

8.54e-051144222826121
Pubmed

KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.

SYNE1 SYNE2

1.21e-041344221177258
Pubmed

Internally tagged ubiquitin: a tool to identify linear polyubiquitin-modified proteins by mass spectrometry.

TNIP1 OPTN

1.41e-041444228319114
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

SYNE1 SYNE2

1.41e-041444219874786
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 TNIP1 SYNE1 SYNE2

1.89e-0422544412168954
Pubmed

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.

ATG5 TNIP1

2.36e-041844219838193
Pubmed

Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation.

PRDM12 TRPM8

2.93e-042044233789102
Pubmed

A human MAP kinase interactome.

EVPL PNISR SYNE1 GOLGB1 CEP290

3.62e-0448644520936779
Pubmed

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.

TNIP1 CAT OPTN

4.44e-0411744336898370
Pubmed

Bardet-Biedl Syndrome Overview

IFT74 CEP290

5.38e-042744220301537
Pubmed

A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.

ATG5 TNIP1

5.38e-042744223740937
Pubmed

Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.

GRIN3A SYNE1

5.38e-042744218649358
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

USP34 CHGB CSNK1G3

5.78e-0412844330995482
Pubmed

Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.

FMO1 FMO2

6.65e-043044220529763
Pubmed

SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.

TNIP1 OPTN

7.11e-043144227307491
Pubmed

Lem2 is essential for cardiac development by maintaining nuclear integrity.

SYNE1 SYNE2

7.57e-043244237067297
Pubmed

Identification of polyubiquitin binding proteins involved in NF-kappaB signaling using protein arrays.

TNIP1 OPTN

7.57e-043244219285159
Pubmed

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.

PRDM12 TRPM8

8.06e-043344230917309
Pubmed

The CARM1-p300-c-Myc-Max (CPCM) transcriptional complex regulates the expression of CUL4A/4B and affects the stability of CRL4 E3 ligases in colorectal cancer.

USP34 TRRAP

8.06e-043344232140074
Pubmed

HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.

TRRAP GOLGB1

8.55e-043444225925205
Pubmed

Reduced lifespan of mice lacking catalase correlates with altered lipid metabolism without oxidative damage or premature aging.

ATG5 CAT

9.06e-043544230818059
Pubmed

Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins.

TNIP1 GOLGB1

9.06e-043544227812135
Pubmed

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

TRAF3IP2 TNIP1 MMEL1 IPMK

9.15e-0434244423128233
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

USP34 MYH15 OPTN POLR1A TRRAP IPMK

9.54e-0491044636736316
Pubmed

ZNF212 promotes genomic integrity through direct interaction with TRAIP.

TNIP1 GOLGB1

1.01e-033744236594163
Pubmed

Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.

ATG5 TNIP1

1.07e-033844223273568
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATG5 USP34 N4BP2L2 PNISR IFT74 SYNE1 CEP290

1.07e-03128544735914814
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

ATG5 GOLGB1 CEP290

1.08e-0315944330581152
Pubmed

The DNA sequence and analysis of human chromosome 6.

ATG5 TRAF3IP2 AARS2 PNISR SYNE1

1.10e-0362244514574404
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

EVPL OPTN AARS2 GOLGB1

1.11e-0336044433111431
Pubmed

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

SMARCB1 TNIP1 POLR1A

1.14e-0316244314743216
Cytoband1q24.3

FMO1 FMO2

1.69e-04204421q24.3
CytobandEnsembl 112 genes in cytogenetic band chr14q23

SYNE2 KCNH5 LRRC9

2.70e-04130443chr14q23
Cytoband14q23.1

KCNH5 LRRC9

9.44e-044744214q23.1
Cytoband6q21

ATG5 TRAF3IP2

3.87e-03964426q21
CytobandEnsembl 112 genes in cytogenetic band chr5q23

LVRN CSNK1G3

5.68e-03117442chr5q23
CytobandEnsembl 112 genes in cytogenetic band chr6q21

ATG5 TRAF3IP2

6.06e-03121442chr6q21
CytobandEnsembl 112 genes in cytogenetic band chr1q24

FMO1 FMO2

6.86e-03129442chr1q24
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

1.19e-0542621252
GeneFamilyEF-hand domain containing|Plakins

EVPL EVPLL

5.54e-058262939
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

N4BP2L2 CAT PNISR IFT74 SYNE2 CEP290

3.63e-05311436Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 N4BP2L2 PNISR SYNE1 GOLGB1 SYNE2

4.26e-08199446f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1 FMO2 IPMK

1.03e-06184445c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1 FMO2 IPMK

1.03e-061844457c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 N4BP2L2 PNISR SYNE1 SYNE2

1.45e-0619744557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 N4BP2L2 PNISR GOLGB1 SYNE2

1.56e-0620044512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellCOVID-19_Moderate-MAIT|World / disease group, cell group and cell class

EVPL SUN3 DSEL SYNE2

1.87e-05160444bf73c5fe87c1f243edec17d7a2c30fae5e2cfd6b
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

USP34 N4BP2L2 PNISR SYNE2

1.97e-05162444b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

N4BP2L2 SYNE1 GOLGB1 SYNE2

2.43e-051714442e9a20f8980b78325c52065a9c14ab3656267c05
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_straight_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1 FMO2

2.97e-05180444b34d933cdabf692f02eaaf65c2aaca1fb9510627
ToppCelldroplet-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 FMO1 FMO2 IPMK

3.23e-05184444e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1 FMO2

3.30e-051854443e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1 FMO2

3.30e-051854440ff4148b4701003d9d594e0da8261176fb13aa59
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

OPTN PNISR SYNE1 SYNE2

3.59e-051894440e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

N4BP2L2 PNISR GOLGB1 SYNE2

3.59e-051894442c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

N4BP2L2 OPTN SYNE1 SYNE2

3.90e-05193444a594f89a18273797506287d9e22f72abe53e4920
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

N4BP2L2 OPTN SYNE1 SYNE2

3.98e-051944449588a9b4baebbae08e13d201d4b9dfcf0e6521fb
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

N4BP2L2 OPTN SYNE1 SYNE2

4.06e-0519544453528e5788083bce5a8d4611ab3808878e6a9cd3
ToppCellHealthy-CD4+_CTL|Healthy / disease group, cell group and cell class

OPTN DSEL SYNE1 SYNE2

4.14e-051964449da0ea4ad84d6e20e4349d3d1a8cc4d61d08c84f
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 SYNE2 CEP290 LRRC9

4.22e-0519744474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FMO2 GOLGB1 SYNE2 CEP290

4.22e-051974443d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellLPS_only-Epithelial_alveolar|LPS_only / Treatment groups by lineage, cell group, cell type

CAT FMO2 DSEL SYNE2

4.30e-05198444655df75b9692d815c7f6910275e1f684ac63bf62
ToppCellHealthy_donor|World / disease group, cell group and cell class (v2)

N4BP2L2 PNISR SYNE1 SYNE2

4.30e-051984441ed0b50c9754727a05c27b21f3546bf2e37eef7f
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

FMO2 DSEL GOLGB1 SYNE2

4.30e-0519844485f424cd9bb3117c9e322031024aabb87696ce47
ToppCellPBMC-Convalescent-Lymphocyte-T/NK|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

N4BP2L2 PNISR SYNE1 SYNE2

4.30e-051984444633e379893a26a746f8e29302cc54bbe04dd23f
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

N4BP2L2 OPTN SYNE1 SYNE2

4.39e-05199444db05c16d80f5a74bfa048a5c92917d312d26f769
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

FMO2 GOLGB1 SYNE2 CEP290

4.48e-052004442dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellPBMC-Severe-Lymphocyte-T/NK|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

OPTN PNISR SYNE1 SYNE2

4.48e-0520044473b91cb66c375b44e852404a4a445cf2b9595aee
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FMO2 DSEL GOLGB1 SYNE2

4.48e-05200444ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK|COVID-19_Severe / Disease, condition lineage and cell class

OPTN PNISR SYNE1 SYNE2

4.48e-05200444323cb89add511fbe9896b4df0f1f2b7fdbb6c649
ToppCellCOVID-19_Severe-Lymphoid_T/NK|COVID-19_Severe / Disease group, lineage and cell class

OPTN PNISR SYNE1 SYNE2

4.48e-052004449fc818bf5c9133fc2fece47980e71fd3f8603558
ToppCellPBMC-Severe-Lymphocyte-T/NK|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OPTN PNISR SYNE1 SYNE2

4.48e-05200444f1c8780d64b58b6fb84fffbc27f0ad337b1a6e56
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

N4BP2L2 SYNE1 SYNE2

2.32e-0412144319333a660800b583fa27b495c1f7828e6636a257
ToppCellEpithelial-Epithelial-D_(Clara-Club_cells)|Epithelial / shred on cell class and cell subclass (v4)

TRPM8 SUN3 FMO2

2.43e-04123443caa1576f1b5eb592d522be61c090ac444e277ac5
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

CHGB SYNE1 SCAMP1

3.20e-04135443ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SYNE1 GOLGB1 SYNE2

3.20e-04135443ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

N4BP2L2 PNISR GOLGB1

3.20e-04135443b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellHealthy-CD4+_T_activated|World / disease group, cell group and cell class

EVPL GRIN3A IFT74

3.56e-04140443407691970ec72a3afb45e431cf48814546b8acff
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

FMO1 MMEL1 KCNH5

3.78e-041434430118772a5bc7c48465e9b314be55203412e8d67c
ToppCellAT1-AT2_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

EVPL MYH15 FMO2

3.94e-04145443cd5de30fd948024e3ad043c9411ce9f2722178b2
ToppCellHealthy-CD4+_T_activated|Healthy / disease group, cell group and cell class

EVPL GRIN3A IFT74

3.94e-0414544345e8089fdf7d6f69b383816d8945e39fba24c873
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

N4BP2L2 PNISR GOLGB1

4.10e-0414744394998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRDM12 GRIN3A SYNE1

4.35e-041504438645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EVPL CHGB MMEL1

4.97e-041574436a0aa66964eecbbc232abf1d2e6c8422e4ce69d0
ToppCellLeuk-UTI-Lymphocyte-T_NK-gdT|Leuk-UTI / Disease, Lineage and Cell Type

OPTN SYNE1 SYNE2

5.06e-04158443c4b0af25608cee3d0d2b0193f5ff45d9dc87078b
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EVPL CHGB MMEL1

5.35e-0416144322fea192cd5f6d3544533d8b10e1d74dfedf0f05
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FMO2 GRIN3A SYNE1

5.64e-04164443f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DSEL RPP40 SYNE2

5.95e-041674433b717d33aaf1ef0869cc4bca8432ba8008875cc5
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

OPTN SYNE1 SYNE2

6.05e-04168443b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MMEL1 RPP40 SCAMP1

6.05e-041684432fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO1 FMO2 SYNE2

6.59e-04173443c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCellmild_COVID-19_(asymptomatic)-gd_T|World / disease group, cell group and cell class (v2)

OPTN SYNE1 SYNE2

6.59e-04173443b6615ff02f5017d7150b1e33b53f8c7a26081a0d
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHGB SYNE1 SYNE2

6.81e-04175443cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TRPM8 SYNE1 SYNE2

6.81e-04175443cc2428150987911d0d382e8177918724aa69f85c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

OPTN SYNE1 SYNE2

6.93e-041764435914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DIO1 FMO1 SYNE2

6.93e-041764431595dbeee336a81e581325d63208ec6262664ee9
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-HSC-MPP|lymph-node_spleen / Manually curated celltypes from each tissue

EVPL CAT SUN3

6.93e-04176443de67ed15a50d2515ba6d152c1011a3367f77aedd
ToppCellInt-URO-Lymphocyte-T_NK-gdT|Int-URO / Disease, Lineage and Cell Type

SYNE1 SYNE2 CEP290

6.93e-0417644315016a73c953d8d3e7c32a05ead5e7261f9914ca
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TRPM8 SYNE1 SYNE2

6.93e-04176443003076f1a983409ddf31b9c19e61c1facdd72566
ToppCellfacs-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1

7.04e-041774437f58286fc8797e9bdcf8ece0849f55680905955d
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 SYNE1 SYNE2

7.16e-0417844301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OPTN SYNE1 SYNE2

7.16e-0417844315a99080e9f669572ab6d82934f324e6714846c1
ToppCellControl-Lymphocyte-T_NK-CD4_CTL|Control / Disease, Lineage and Cell Type

OPTN SYNE1 SYNE2

7.16e-0417844332fbb7a8d7daa7cb37f42923514acbb9090e6811
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OPTN SYNE1 SYNE2

7.16e-04178443200308e109abb7e6f8816a6f8cce6d56862d4098
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DIO1 GOLGB1 SYNE2

7.39e-04180443f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FMO2 CHGB KCNH5

7.39e-04180443368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

EVPL FMO2 ABCA7

7.51e-04181443ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OPTN SYNE1 SYNE2

7.51e-04181443566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DIO1 FMO1 SYNE2

7.51e-041814439542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DIO1 FMO1 SYNE2

7.51e-041814438f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1

7.51e-04181443bec7076efe94898213a62db72d171d737949977e
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

USP34 N4BP2L2 SYNE2

7.51e-04181443f2315414e714ac86211546a935660c4be6e85f1b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OPTN SYNE1 SYNE2

7.51e-04181443db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1

7.51e-04181443cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DSEL SYNE1 SYNE2

7.75e-04183443983ca1342ddd365e1f1df32a456394b002b10e41
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMK+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

OPTN SYNE1 SYNE2

7.75e-0418344379defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

N4BP2L2 OPTN SYNE2

7.75e-041834438f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1

7.88e-0418444345577ff91c3b2b303acd97239dde2463ea7a429c
ToppCell(1)_T_cells-(1)_T_regulatory|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MYH15 CHGB MMEL1

7.88e-041844433cbf81757653652441843d85cb7ec1dcf25ca1b0
ToppCellHealthy/Control-CD4+_CTL|Healthy/Control / Disease group and Cell class

OPTN SYNE1 SYNE2

7.88e-041844436c6ffa150f81e456f88e9065de90c2dcda417589
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 CAT FMO1

7.88e-041844433d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

N4BP2L2 OPTN SYNE2

8.00e-04185443406b52516b26e9fe2c9e768950af447ec7ad5f3e
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

OPTN SYNE1 SYNE2

8.00e-04185443097d628f92e13250c15b550f2fd1f4225fc07558
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

N4BP2L2 OPTN SYNE2

8.00e-04185443f2ebd099c8dfcfaca4298bcdd618c50701a9c2c8
ToppCellmild_COVID-19_(asymptomatic)-gd_T|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

OPTN SYNE1 SYNE2

8.13e-041864435fa3ed834898aa06aae15a8ade7ab93a6e4744f8
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD8+_T_activated|COVID-19_Severe / Disease group, lineage and cell class

OPTN SYNE1 SYNE2

8.25e-041874434c4c4406e16a15dedcd50bbcc2059d722a2e3d2c
ToppCellControl-Lymphocyte-T_NK-CD8_TEM|Control / Disease, Lineage and Cell Type

OPTN SYNE1 SYNE2

8.25e-041874437fdff970a9397305d0b8194c00a043cc69dcca12
ToppCelldroplet-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO1 FMO2 IPMK

8.25e-04187443236e9857729670e87eed30fad58f49e1f56e4a85
ToppCellHealthy/Control-CD4+_CTL|World / Disease group and Cell class

OPTN SYNE1 SYNE2

8.25e-04187443d54d3214d77a9469e94a16c00a80626fd4953e2b
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

N4BP2L2 PNISR GOLGB1

8.25e-041874430099def970fbc828756fbf853eca2ce77b8cd342
ToppCellmild_COVID-19-CD4+_CTL|mild_COVID-19 / disease group, cell group and cell class (v2)

OPTN SYNE1 SYNE2

8.25e-0418744349196d07e4716c87d33229a4569bdb6b4613b3eb
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

OPTN SYNE1 SYNE2

8.25e-041874430bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

OPTN SYNE1 SYNE2

8.38e-04188443f8e6247bedc0ba494c5bb551539cb8ba5a97f557
ToppCellfacs-MAT-Fat-3m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAT FMO1 FMO2

8.38e-041884437da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 GOLGB1 SYNE2

8.38e-04188443ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell3'_v3-blood-Lymphocytic_T_CD8-Trm/em_CD8|blood / Manually curated celltypes from each tissue

OPTN SYNE1 SYNE2

8.38e-0418844321730497f95dc271e4cdfaaf1da8b9ac6eec2ded
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAT FMO1 FMO2

8.38e-04188443c1f64311ff05093b2f4f672e33f5f75e3bc8a8db
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

OPTN SYNE1 SYNE2

8.38e-041884438155bc5476fc333bedcc78c5ddcc8e4912536caa
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAT FMO1 FMO2

8.38e-04188443b483b4629695764568bcbd1d527d614824147783
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

OPTN SYNE1 SYNE2

8.38e-041884432513ca0efa73c09a3406b99e2876982d78b173d7
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

IFT74 SYNE1 CEP290

8.38e-041884438f30535a32968a81a304315a49c0d90a77d36948
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SYNE1 GOLGB1 SYNE2

1.48e-0449233GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

PNISR SYNE1 GOLGB1

1.57e-0450233GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

N4BP2L2 PNISR SYNE2

1.57e-0450233GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_UNASSIGNED_1
DrugTCVC

CAT FMO1 FMO2

5.61e-079443CID000108091
Drugp-tolyl sulfoxide

CAT FMO1 FMO2

1.46e-0612443CID000015680
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.30e-054442cv:CN293514
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

2.17e-055442C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

2.17e-055442C0410190
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

3.25e-056442cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

3.25e-056442C0410189
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

4.54e-057442C0751337
DiseasePsoriasis

TRAF3IP2 TNIP1 CAT

8.56e-0557443C0033860
DiseasePustulosis of Palms and Soles

TRAF3IP2 TNIP1 CAT

8.56e-0557443C0030246
Diseaseunipolar depression, bipolar disorder

MYH15 SYNE1 SCAMP1 SYNE2

8.65e-05156444EFO_0003761, MONDO_0004985
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

1.42e-0412442DOID:11726 (implicated_via_orthology)
DiseaseMethionine sulfoxide measurement

FMO1 FMO2

1.42e-0412442EFO_0021650
Diseaselevel of Sphingomyelin (d32:1) in blood serum

SYNE2 KCNH5

2.91e-0417442OBA_2045173
Diseasemultiple myeloma

ATG5 DIO1 DSEL

6.29e-04112443EFO_0001378
Diseasesystemic scleroderma, systemic lupus erythematosus

ATG5 TNIP1

6.90e-0426442EFO_0000717, MONDO_0007915
Diseasepsoriasis

TRAF3IP2 TNIP1 LIPK SYNE2

7.27e-04273444EFO_0000676
Diseasevisceral heterotaxy (implicated_via_orthology)

IFT74 CEP290

1.40e-0337442DOID:0050545 (implicated_via_orthology)
Diseasesex interaction measurement, Crohn's disease

ATG5 USP34

1.40e-0337442EFO_0000384, EFO_0008343
Diseasesystemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus

ATG5 TNIP1

1.48e-0338442EFO_0000685, EFO_0000717, EFO_0000783, MONDO_0007915

Protein segments in the cluster

PeptideGeneStartEntry
QMQHWKEQRAAQKAD

CAT

11

P04040
SNAEQDDLWRHFQMA

LVRN

536

Q6Q4G3
KQLWMGLQNDRFDQF

ATG5

151

Q9H1Y0
NNKGWHSMVAFVNRA

ABCA7

1476

Q8IZY2
GSYEAMMDDQNHNNW

CACUL1

11

Q86Y37
RQGHSNFKQMQELNW

LRRC9

1086

Q6ZRR7
FSNKSANMDHWQQRF

MAT2B

206

Q9NZL9
AYDNWNEQRMALHKD

KIAA1109

3291

Q2LD37
NNMGAHEEKKEDWNN

KCNH5

816

Q8NCM2
AHQEALKMEWQNFLN

EVPLL

261

A8MZ36
AHQEALKMEWQNFLN

EVPL

306

Q92817
KNNNLMWEVFNEDGT

PRDM12

131

Q9H4Q4
DNGRNFDKNGNMMDW

MMEL1

621

Q495T6
MQQSKNQSADHRAAW

CSNK1G3

356

Q9Y6M4
EQDNGWKSMSQEHLN

IPMK

341

Q8NFU5
NNFFIWNLQHDPMGK

GRIN3A

461

Q8TCU5
DGWAFKNNMDIRNHQ

DIO1

161

P49895
ERKWQHLEQNNFAMK

IFT74

546

Q96LB3
QNKFHEERQMAWDQR

CEP290

1396

O15078
MERKINNWLNHANYG

FMO1

256

Q01740
IEQQMNRWFNHENYG

FMO2

256

Q99518
WKSSHFERRDNMNDN

CHGB

531

P05060
RHFNINNLDNNWLKM

DSEL

296

Q8IZU8
NNQAMKGRFEELSAW

OPTN

61

Q96CV9
NQDYWLQMAVGANDH

RPP40

346

O75818
WQDAHLGKDQRDFNM

POLR1A

846

O95602
MVHEGNQRWDNLQKR

SYNE1

8081

Q8NF91
KQMVHEGNQRWDNLQ

SYNE2

6216

Q8WXH0
NFTNEKLQQFFNWHM

MYH15

491

Q9Y2K3
DGQKLRDAFTWNMNE

SMARCB1

196

Q12824
REMQNLSQHGRKNNW

SCAMP1

106

O15126
WNLVFMQHNREADGS

AARS2

241

Q5JTZ9
AEHQFSFMEKRNQWL

TRAF3IP2

136

O43734
VNKQWDQHFRSMKQQ

TNIP1

316

Q15025
QNREFMVFAHAQWKA

UGT1A10

86

Q9HAW8
KMGQEHSLFFNNNNW

STPG4

231

Q8N801
KDGMDNNHNWNTHGD

SUN3

141

Q8TAQ9
NHGNFQGDSNFNRMW

PNISR

76

Q8TF01
DDLGRWHQKNAMNLN

TEX33

246

O43247
WFLNQVRSKDQHAMG

USP34

1031

Q70CQ2
IWHDNMQFLQDKNIF

USP34

2261

Q70CQ2
QHMEGTQINQSEKWN

TRPM8

76

Q7Z2W7
FQERHRKENMAATNW

TRRAP

1676

Q9Y4A5
IGMKWENQNIDDQHQ

ZNF44

91

P15621
KAMASLQNERDHLWN

GOLGB1

2836

Q14789
FDWGNSDQNMMHFHQ

LIPK

306

Q5VXJ0
LGDAHDWNQNRAKQA

N4BP2L2

451

Q92802