Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3C RIMBP3 RIMBP3B	1.62e-05	5	237	3	GO:0030156
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SPEG CHKB TYK2 MYO3A SPHK1 PIK3CG SHPK MAP3K10 PIP5K1A KHK ULK1 NME7 RPS6KL1 PKN3 CAD ITPKC MTOR NEK8 PAN3 ALPK2 PINK1	1.17e-04	709	237	21	GO:0016773
GeneOntologyMolecularFunction	kinase activity	SPEG CMPK2 CHKB TYK2 MYO3A SPHK1 PIK3CG SHPK MAP3K10 PIP5K1A KHK ULK1 NME7 RPS6KL1 PKN3 CAD ITPKC MTOR NEK8 PAN3 ALPK2 PINK1	1.21e-04	764	237	22	GO:0016301
GeneOntologyMolecularFunction	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	PFAS GMPS CAD	1.86e-04	10	237	3	GO:0016884
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	SPEG CMPK2 CHKB TYK2 MYO3A SPHK1 PIK3CG SHPK MAP3K10 PIP5K1A KHK ULK1 NME7 RPS6KL1 PKN3 CAD ITPKC RPAP1 MTOR NEK8 PAN3 GDPGP1 ALPK2 PINK1	3.47e-04	938	237	24	GO:0016772
GeneOntologyBiologicalProcess	positive regulation of AMPA receptor activity	NLGN3 ARC SHANK3	1.44e-05	5	235	3	GO:2000969
GeneOntologyBiologicalProcess	cell morphogenesis	NES CDC42EP4 RAPH1 SYT17 DACT2 PLXND1 ITGA7 PLXNB2 KLF2 NLGN3 MYO3A HMCN2 METRN SSH1 GLI3 ARC ADAM17 ULK1 DMRT1 SZT2 COL27A1 BCAN CPNE5 PIAS2 SHANK3 MAP1S TIAM1 UNK ROBO1 CDH3 MYO16	1.58e-05	1194	235	31	GO:0000902
Domain	GATASE_TYPE_1	PFAS GMPS CAD	3.82e-05	6	235	3	PS51273
Domain	GATASE	PFAS GMPS CAD	3.82e-05	6	235	3	IPR017926
Domain	SH3_2	MAP3K10 RIMBP3C MIA3 SHANK3 RIMBP3 SORBS3 RIMBP3B	1.05e-04	86	235	7	PF07653
Domain	SH3_2	MAP3K10 RIMBP3C MIA3 SHANK3 RIMBP3 SORBS3 RIMBP3B	1.05e-04	86	235	7	IPR011511
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	REPS1 KMT2B MFHAS1 TMEM94 SPEG PEX6 PFAS PLXND1 DYSF PLXNB2 ABCA7 PLEKHH3 TYK2 PRR12 SCAF1 SLC38A10 SSH1 NFATC1 SPHK1 MCM3AP ARC WDR90 ULK1 HOXB13 PKN3 ITPRIPL2 SZT2 GTSE1 MUS81 HUWE1 RASSF7 BAHD1 SYNE4 MFSD12 FAM83H KMT2D LLGL2 SCAP SLC2A4RG RPAP1 MAP1S MEGF6 MTOR NEK8 SORBS3 POFUT1 PCNT	9.96e-24	1105	240	47	35748872
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PEX6 PFAS HNRNPF TYK2 PRR12 PRRC2C SUPV3L1 RECQL4 PIP5K1A ULK1 NXF1 LRRC41 MIA3 RAP1GAP VTN ATN1 LONP2 MFSD12 LLGL2 RPAP1 ARHGEF1 ARMC5	1.14e-09	650	240	22	38777146
Pubmed	Defining the membrane proteome of NK cells.	ABHD15 CCDC88B HNRNPF CLCC1 HNRNPH1 UBR5 PIK3CG PRRC2C RECQL4 ADAM17 HEATR5B LRRC41 MIA3 CAD LONP2 GTSE1 PHRF1 HUWE1 MTOR LNPEP PRF1 ADGRE5 POFUT1 ARHGAP45 PCNT	6.40e-07	1168	240	25	19946888
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ZGRF1 PFAS NFATC1 UBR5 PRRC2C MCM3AP BSN NXF1 CAD RBBP4 FAAP20 HUWE1 PIAS2 RIMBP3 TBC1D8 UNK PCNT	8.48e-07	588	240	17	38580884
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TMEM94 SPEG ARHGEF17 UBR5 PRRC2C MCM3AP KATNIP ULK1 DLGAP4 FRMPD1 RPAP1 PHF3 SEZ6L PCNT	1.09e-06	407	240	14	12693553
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3C RIMBP3 RIMBP3B	1.29e-06	4	240	3	19091768
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	PODNL1 TRPS1 PFAS HNRNPH1 PLEKHH3 PHF1 NFATC1 SVIL SCAPER RIMBP3C LONP2 NPIPB11 PIAS2 SHANK3 UBE2O NKD2 PHF3 ZNF646	1.70e-06	689	240	18	36543142
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	ECD PFAS PTPN12 UBR5 UTRN MIA3 TBC1D8 UBE2O UNK ROBO1	2.16e-06	209	240	10	36779422
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2B RAPH1 HNRNPF HNRNPH1 SCAF1 MYO3A SSH1 SVIL ATN1 GTSE1 PHRF1 HUWE1 HEXIM2 KMT2D RPAP1 MAP1S PHF3 SORBS3 UNK	2.16e-06	774	240	19	15302935
Pubmed	Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3.	GDF10 SFTPA2 SFTPA1	3.21e-06	5	240	3	8679252
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3C RIMBP3 RIMBP3B	3.21e-06	5	240	3	17855024
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NES PFAS HNRNPF GMPS UBR5 PRRC2C MCM3AP UTRN NXF1 CAD RBBP4 PHRF1 HUWE1 UBE2O MTOR PHF3 PCNT	3.47e-06	653	240	17	22586326
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAM47A KMT2B ARHGEF17 SNAI3 HNRNPF HNRNPH1 GMPS SCAF1 SLC38A10 MCM3AP RECQL4 UTRN NXF1 TICRR HUWE1 PRR35 RPAP1 MEGF6	4.24e-06	736	240	18	29676528
Pubmed	Molecular embryology of the lung: then, now, and in the future.	SFTPA2 GLI3 SFTPA1	6.39e-06	6	240	3	10330024
Pubmed	Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.	NES PRR12 PIP5K1A MIA3 DLGAP4 MAP1S ARHGEF1 MYO16	7.30e-06	143	240	8	32560809
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NES CDC42EP4 RAPH1 ARHGEF17 PRRC2C SVIL NECTIN2 MAP3K10 UTRN RAP1GAP GTSE1 RASSF7 FAM83H NKD2 TIAM1 MTOR PHF3 ARHGEF1 PAN3	9.83e-06	861	240	19	36931259
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	RAPH1 OTUD1 ECD MKRN2 NR4A1 TELO2 UBR5 MCM3AP KATNIP HEATR5B RAP1GAP C9orf40 GTSE1 RASSF7 HEXIM2 RPAP1 MTOR ARHGEF1 FKBPL PAN3 GPSM1	1.23e-05	1038	240	21	26673895
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RAPH1 TRPS1 PFAS CLCC1 GMPS PTPN9 PTPN12 SSH1 TELO2 SVIL NECTIN2 UTRN MIA3 CAD HUWE1 KMT2D TIAM1 LNPEP SORBS3 ROBO1 PCNT	1.44e-05	1049	240	21	27880917
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TRPS1 YJEFN3 HNRNPF CLCC1 TYK2 GMPS NLGN3 NFATC1 NECTIN2 PIP5K1A KATNIP UTRN RPS6KL1 LRRC41 MIA3 RBBP4 UVSSA FRMPD1 HUWE1 OGDH HEXIM2 FOXP4 MEGF6 PAN3 IL6R PCNT	1.49e-05	1489	240	26	28611215
Pubmed	Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping.	ACO2 CHKB SHANK3 RIMBP3	2.11e-05	24	240	4	11258795
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DENND2A PLXND1 MESD TELO2 ARHGAP31 WDR90 BSN SZT2 UVSSA PHRF1 BAHD1 UBE2O UNK ZNF646	2.14e-05	529	240	14	14621295
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	AKAP17A TRPS1 PEX6 ABCA7 TYK2 SCAF1 HMCN2 TELO2 UBR5 GLI3 MCM3AP SCAPER ADAM17 LRRC41 ATN1 RBBP4 PHRF1 FAM83H FOXP4 SEZ6L ZNF646	3.56e-05	1116	240	21	31753913
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2B NAB2 TRPS1 MIDEAS PRR12 MCM3AP TPRX1 ATN1 PIAS2 FOXP4 KMT2D	3.67e-05	351	240	11	38297188
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	PFAS HNRNPF SSH1 UBR5 GLI3 LONP2 HUWE1 FAM83H MAP1S	3.70e-05	232	240	9	25515538
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	AKAP17A ARHGEF17 PLXNB2 GMPS MESD PTPN12 UBR5 PRRC2C PIP5K1A ULK1 CARS2 SDC4 MIA3 CAD UBXN1 PIR MFSD12 MAP1S LNPEP ARHGEF1 SORBS3 ROBO1 POFUT1	3.75e-05	1297	240	23	33545068
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	HSPA12B SCAF1 HOXC13 GLI3 SCAPER BSN SHANK3 PHF3 SIX5	3.82e-05	233	240	9	37704626
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KMT2B RAPH1 ZGRF1 TRPS1 PRR12 UBR5 UTRN NXF1 HUWE1 PIAS2 KMT2D PCNT	3.83e-05	418	240	12	34709266
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	PLXNB2 SLC38A10 TELO2 SUPV3L1 LLGL2 MAP1S MTOR CDH3	4.34e-05	183	240	8	31932471
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	BORCS6 PRR12 UBR5 ARHGAP31 MCM3AP SVIL GTSE1 KMT2D	4.51e-05	184	240	8	32908313
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NES NLGN3 PTPN9 SSH1 UBR5 PRRC2C SVIL ARC BSN MIA3 CAD DLGAP4 HUWE1 SHANK3 UBE2O MTOR DCHS1 FRMPD3 PCNT	4.53e-05	963	240	19	28671696
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	NES HNRNPF HNRNPH1 PRRC2C SVIL UTRN MIA3 VTN OGDH ARHGEF1 PCNT	4.61e-05	360	240	11	33111431
Pubmed	Genome-scale RNAi screen for host factors required for HIV replication.	OPN4 ONECUT1 KLF2 PHF1 NLGN3 HMCN2 UBR5 MCM3AP PPM1N KRTCAP3 ADGRE5	4.73e-05	361	240	11	18976975
Pubmed	Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.	SIGLEC5 SIGLEC14	4.74e-05	2	240	2	24799499
Pubmed	The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization.	HNRNPF HNRNPH1	4.74e-05	2	240	2	7512260
Pubmed	Maternal surfactant protein A influences the immunoprotective properties of milk in a murine model.	SFTPA2 SFTPA1	4.74e-05	2	240	2	24858142
Pubmed	Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.	SFTPA2 SFTPA1	4.74e-05	2	240	2	24954098
Pubmed	Demyelinated axons and motor function are protected by genetic deletion of perforin in a mouse model of multiple sclerosis.	TYK2 PRF1	4.74e-05	2	240	2	19680139
Pubmed	The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling.	NR4A1 MTOR	4.74e-05	2	240	2	23197407
Pubmed	Surfactant protein A modulates neuroinflammation in adult mice upon pulmonary infection.	SFTPA2 SFTPA1	4.74e-05	2	240	2	38964703
Pubmed	Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation.	SFTPA2 SFTPA1	4.74e-05	2	240	2	22219327
Pubmed	Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid.	SFTPA2 SFTPA1	4.74e-05	2	240	2	15890661
Pubmed	Enhanced lung injury and delayed clearance of Pneumocystis carinii in surfactant protein A-deficient mice: attenuation of cytokine responses and reactive oxygen-nitrogen species.	SFTPA2 SFTPA1	4.74e-05	2	240	2	15385504
Pubmed	Surfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference.	SFTPA2 SFTPA1	4.74e-05	2	240	2	23038062
Pubmed	Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor.	PIK3CG MTOR	4.74e-05	2	240	2	20166697
Pubmed	Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice.	SFTPA2 SFTPA1	4.74e-05	2	240	2	17307210
Pubmed	Surfactant protein A modulates induction of regulatory T cells via TGF-β.	SFTPA2 SFTPA1	4.74e-05	2	240	2	22474025
Pubmed	Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice.	SFTPA2 SFTPA1	4.74e-05	2	240	2	38553537
Pubmed	Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).	KMT2B KMT2D	4.74e-05	2	240	2	35640156
Pubmed	Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum.	SFTPA2 SFTPA1	4.74e-05	2	240	2	33510368
Pubmed	Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages.	SFTPA2 SFTPA1	4.74e-05	2	240	2	11342662
Pubmed	Post-transcriptional regulation of mu-opioid receptor: role of the RNA-binding proteins heterogeneous nuclear ribonucleoprotein H1 and F.	HNRNPF HNRNPH1	4.74e-05	2	240	2	21739230
Pubmed	Lung development in the mouse embryo.	SFTPA2 SFTPA1	4.74e-05	2	240	2	2050021
Pubmed	HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.	HUWE1 TIAM1	4.74e-05	2	240	2	25543140
Pubmed	Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.	SFTPA2 SFTPA1	4.74e-05	2	240	2	12922979
Pubmed	Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14.	SIGLEC5 SIGLEC14	4.74e-05	2	240	2	26459514
Pubmed	Novel role for surfactant protein A in gastrointestinal graft-versus-host disease.	SFTPA2 SFTPA1	4.74e-05	2	240	2	22508928
Pubmed	Signaling Pathways That Mediate Alveolar Macrophage Activation by Surfactant Protein A and IL-4.	SFTPA2 SFTPA1	4.74e-05	2	240	2	35444643
Pubmed	Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues.	DHTKD1 OGDH	4.74e-05	2	240	2	32024885
Pubmed	Myoblast Migration and Directional Persistence Affected by Syndecan-4-Mediated Tiam-1 Expression and Distribution.	SDC4 TIAM1	4.74e-05	2	240	2	32012800
Pubmed	Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus.	SFTPA2 SFTPA1	4.74e-05	2	240	2	11867335
Pubmed	SP-A preserves airway homeostasis during Mycoplasma pneumoniae infection in mice.	SFTPA2 SFTPA1	4.74e-05	2	240	2	19494306
Pubmed	Characterization of a second human pulmonary surfactant-associated protein SP-A gene.	SFTPA2 SFTPA1	4.74e-05	2	240	2	1372511
Pubmed	The Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensing.	SFTPA2 SFTPA1	4.74e-05	2	240	2	21205009
Pubmed	Surfactant protein A binds flagellin enhancing phagocytosis and IL-1β production.	SFTPA2 SFTPA1	4.74e-05	2	240	2	24312669
Pubmed	Effect of cysteine 85 on biochemical properties and biological function of human surfactant protein A variants.	SFTPA2 SFTPA1	4.74e-05	2	240	2	17580966
Pubmed	The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins.	FRMPD1 GPSM1	4.74e-05	2	240	2	18566450
Pubmed	A disintegrin and metalloprotease 17 dynamic interaction sequence, the sweet tooth for the human interleukin 6 receptor.	ADAM17 IL6R	4.74e-05	2	240	2	24790088
Pubmed	Polymorphisms in the surfactant protein a gene are associated with the susceptibility to recurrent urinary tract infection in chinese women.	SFTPA2 SFTPA1	4.74e-05	2	240	2	20448439
Pubmed	Type IV pilus of Pseudomonas aeruginosa confers resistance to antimicrobial activities of the pulmonary surfactant protein-A.	SFTPA2 SFTPA1	4.74e-05	2	240	2	24080545
Pubmed	Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.	SFTPA2 SFTPA1	4.74e-05	2	240	2	1443158
Pubmed	Surfactant Protein A and B Gene Polymorphisms and Risk of Respiratory Distress Syndrome in Late-Preterm Neonates.	SFTPA2 SFTPA1	4.74e-05	2	240	2	27835691
Pubmed	Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.	SFTPA2 SFTPA1	4.74e-05	2	240	2	34484180
Pubmed	Surfactant protein-A reduces translocation of mediators from the lung into the circulation.	SFTPA2 SFTPA1	4.74e-05	2	240	2	20715984
Pubmed	Protein tyrosine phosphatase nonreceptor type 12 suppresses the proliferation of renal cell carcinoma by inhibiting the activity of the PI3K/mTOR pathway.	PTPN12 MTOR	4.74e-05	2	240	2	26537073
Pubmed	Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms.	SFTPA2 SFTPA1	4.74e-05	2	240	2	18159253
Pubmed	Regulatory roles of SP-A and exosomes in pneumonia-induced acute lung and kidney injuries.	SFTPA2 SFTPA1	4.74e-05	2	240	2	37256132
Pubmed	Surfactant Protein A, a Novel Regulator for Smooth Muscle Phenotypic Modulation and Vascular Remodeling-Brief Report.	SFTPA2 SFTPA1	4.74e-05	2	240	2	33267655
Pubmed	Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line.	SFTPA2 SFTPA1	4.74e-05	2	240	2	10781424
Pubmed	Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production.	PLXND1 PLXNB2	4.74e-05	2	240	2	22916243
Pubmed	SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved.	SFTPA2 SFTPA1	4.74e-05	2	240	2	29202868
Pubmed	Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F.	HNRNPF HNRNPH1	4.74e-05	2	240	2	23284676
Pubmed	Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene.	SFTPA2 SFTPA1	4.74e-05	2	240	2	20693318
Pubmed	Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice.	SFTPA2 SFTPA1	4.74e-05	2	240	2	9922219
Pubmed	Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.	SFTPA2 SFTPA1	4.74e-05	2	240	2	34917085
Pubmed	A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation.	SFTPA2 SFTPA1	4.74e-05	2	240	2	23475791
Pubmed	siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy.	ULK1 MTOR	4.74e-05	2	240	2	17595159
Pubmed	Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences.	SFTPA2 SFTPA1	4.74e-05	2	240	2	29394894
Pubmed	The small RNA mascRNA differentially regulates TLR-induced proinflammatory and antiviral responses.	HNRNPF HNRNPH1	4.74e-05	2	240	2	34582376
Pubmed	Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2--impact on function.	SFTPA2 SFTPA1	4.74e-05	2	240	2	19392648
Pubmed	Surfactant protein A-deficient mice are susceptible to group B streptococcal infection.	SFTPA2 SFTPA1	4.74e-05	2	240	2	9126996
Pubmed	Hierarchical Phosphorylation of HOXB13 by mTOR Dictates Its Activity and Oncogenic Function in Prostate Cancer.	HOXB13 MTOR	4.74e-05	2	240	2	37409967
Pubmed	Inhibition of PI3K, mTOR and MEK signaling pathways promotes rapid apoptosis in B-lineage ALL in the presence of stromal cell support.	PIK3CG MTOR	4.74e-05	2	240	2	15496972
Pubmed	Pro-angiogenic effect of IFNgamma is dependent on the PI3K/mTOR/translational pathway in human retinal pigmented epithelial cells.	PIK3CG MTOR	4.74e-05	2	240	2	20157617
Pubmed	Effects of surfactant protein-A on the interaction of Pneumocystis murina with its host at different stages of the infection in mice.	SFTPA2 SFTPA1	4.74e-05	2	240	2	19335775
Pubmed	Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice.	SFTPA2 SFTPA1	4.74e-05	2	240	2	33141765
Pubmed	Innate immunity of surfactant protein A in experimental otitis media.	SFTPA2 SFTPA1	4.74e-05	2	240	2	31378117
Pubmed	Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection.	SFTPA2 SFTPA1	4.74e-05	2	240	2	11237812
Pubmed	Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice.	SFTPA2 SFTPA1	4.74e-05	2	240	2	27916681
Pubmed	Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway.	SFTPA2 SFTPA1	4.74e-05	2	240	2	12959932
Pubmed	Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition.	SFTPA2 SFTPA1	4.74e-05	2	240	2	15044702
Interaction	TOP3B interactions	REPS1 KMT2B MFHAS1 TMEM94 SPEG MKRN2 PEX6 PFAS PLXND1 DYSF PLXNB2 ABCA7 PLEKHH3 TYK2 PRR12 SCAF1 SLC38A10 SSH1 NFATC1 SPHK1 MCM3AP SVIL ARC WDR90 ULK1 HOXB13 PKN3 CAD ITPRIPL2 SZT2 GTSE1 MUS81 HUWE1 RASSF7 BAHD1 SYNE4 MFSD12 FAM83H KMT2D LLGL2 SCAP SLC2A4RG RPAP1 MAP1S MEGF6 MTOR NEK8 SORBS3 UNK POFUT1 PCNT	1.51e-12	1470	236	51	int:TOP3B
Cytoband	Ensembl 112 genes in cytogenetic band chr17q25	CDC42EP4 TMEM94 OTOP2 NT5C SLC38A10 SPHK1 TMC8 CCDC40 UBE2O LLGL2 UNK	7.79e-07	307	240	11	chr17q25
Cytoband	17q25.1	TMEM94 OTOP2 NT5C UBE2O LLGL2 UNK	4.48e-06	81	240	6	17q25.1
GeneFamily	PHD finger proteins	KMT2B PHF1 PHRF1 KMT2D PHF20L1 PHF3	1.11e-04	90	152	6	88
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	NES ABHD15 ITGA7 DYSF ARHGEF17 ONECUT1 KLF2 METRN NFATC1 GLI3 SVIL NECTIN2 UTRN SDC4 TICRR ITPRIPL2 CWH43 COL27A1 BCAN VSTM2B CPNE5 RASSF7 FOXP4 LLGL2 SCUBE2 NKD2 ADGRE5 MYO16 SEZ6L	1.91e-07	1074	239	29	M1941
Coexpression	IBRAHIM_NRF2_DOWN	OTUD1 ABCA7 NT5C PLEKHH3 TYK2 RECQL4 WDR90 PKN3 RASSF7 ROBO1	3.52e-06	168	239	10	M42513
Coexpression	GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_UP	PLXND1 PLXNB2 CLCC1 TYK2 CYP7B1 BSN UTRN FHOD3 FAM83H PINK1	1.63e-05	200	239	10	M8853
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	DENND2A CDC42EP4 CRLF1 REPS1 ARHGEF17 SRPX2 METRN NECTIN2 KHK KIF25 RBBP4 DLGAP4 MXRA8 POU3F4 ITPKC LLGL2 SLC2A4RG MEGF6 MTOR PHF3 FKBPL SEZ6L	3.36e-05	909	239	22	M41018
Coexpression	DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN	PFAS ITGA7 ARHGEF17 PLXNB2 TYK2 SLC38A10 KHK ADAM17 ULK1 CAD OGDH	5.03e-05	276	239	11	M3063
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_ILC3_CELL	ABHD15 PLXND1 NFATC1 SVIL ATP10D TIAM1	5.10e-05	72	239	6	M45770
Coexpression	GSE34156_UNTREATED_VS_24H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP	ABHD15 PLXND1 PLXNB2 SLC38A10 GLI3 FAAP20 RNF167 KMT2D SIX5	8.36e-05	196	239	9	M8683
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	CDC42EP4 AKAP17A ZNF275 CHKB DYSF MIDEAS PLXNB2 CES2 TYK2 MCM3AP KATNIP ULK1 UTRN NXF1 WAS C21orf58 SCAP MEGF6 UNK ADGRE5 PCNT	9.22e-05	905	239	21	M40865
Coexpression	GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP	A1BG NR4A1 MIDEAS ABCA7 KLF2 SLC38A10 TMC8 WAS SLC2A4RG	9.39e-05	199	239	9	M6124
Coexpression	GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP	AKAP17A CHKB RXRB KLF2 ULK1 NXF1 WAS ARHGAP45 IL6R	9.39e-05	199	239	9	M4460
Coexpression	GSE20715_WT_VS_TLR4_KO_LUNG_DN	YJEFN3 ABCA7 METRN ARHGAP31 SPHK1 NME7 HOXB13 POU3F4 SHANK3	9.39e-05	199	239	9	M4350
Coexpression	GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP	MIDEAS SNAI3 PHF1 NXF1 KMT2D SLC2A4RG TIAM1 ARHGEF1 ARHGAP45	9.76e-05	200	239	9	M331
Coexpression	GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_UP	MIDEAS SNAI3 KLF2 PHF1 NFATC1 LLGL2 KRTCAP3 ADGRE5 IL6R	9.76e-05	200	239	9	M9748
Coexpression	GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN	ABCA7 KLF2 PHF1 PIK3CG CYB561A3 RNF167 LNPEP ARHGEF1 ARHGAP45	9.76e-05	200	239	9	M9733
Coexpression	GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN	MFHAS1 NAB2 SNAI3 SUPV3L1 NECTIN2 CAD BAHD1 UBE2O ALPK2	9.76e-05	200	239	9	M6461
Coexpression	BILD_E2F3_ONCOGENIC_SIGNATURE	ABHD15 MFHAS1 CMPK2 ZNF275 PLXND1 RECQL4 PKN3 SHANK3 TIAM1 SIX5	1.00e-04	248	239	10	M13061
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	NES DENND2A TMEM94 MKRN2 NAB2 PEX6 NR4A1 ITGA7 CHKB YJEFN3 ARHGEF17 PLXNB2 ABCA7 RXRB PLEKHH3 PHF1 METRN SPHK1 GLI3 SVIL MAP3K10 KATNIP ADAM17 VTN C9orf40 MXRA8 PCDHB9 FHOD3 SHANK3 FOXP4 SLC2A4RG SCUBE2 MEGF6 TIAM1 SORBS3 SIX5 GPSM1 PINK1	1.21e-06	1466	239	38	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PODNL1 CMPK2 SIGLEC5 NR4A1 SPHK1 NECTIN2 KHK TBC1D8 PINK1	1.49e-07	153	239	9	ee6f4770c6e35d59bdeec5b0ecb10119fa8c3ca5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PODNL1 CMPK2 SIGLEC5 NR4A1 SPHK1 NECTIN2 KHK TBC1D8 PINK1	1.49e-07	153	239	9	90cd6efda83c0b4b80eae2c90e7ff45dfd936dc2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Dendritic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PODNL1 CMPK2 SIGLEC5 NR4A1 SPHK1 NECTIN2 KHK TBC1D8 PINK1	1.49e-07	153	239	9	a35149a0c8b4ec9ad27cc4b3d34fba3b8714a6a2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 PKN3 TICRR SHANK3 SEZ6L	1.66e-07	155	239	9	59035d792c26d870a8b097939e97fa47859ba68c
ToppCell	10x5'v1-week_17-19-Lymphocytic_B-B_lineage-immature_B_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ANO9 SYT17 NAB2 NT5C CYB561A3 RPAP1 NEK8 ARMC5 ROBO1	3.82e-07	171	239	9	5636ec11ed1f7aacf98cd9e85853ee1a05bd2cf2
ToppCell	metastatic_Brain-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	RAPH1 SYT17 TRPS1 ARHGAP31 NME7 SIGLEC14 FOXP4 RPAP1 ADGRE5	3.82e-07	171	239	9	0d14bc9688c427ba2265984987dc3eea195b19eb
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PODNL1 SRPX2 UBR5 SPHK1 GLI3 COL27A1 USP29 POU3F4 PIAS2	4.64e-07	175	239	9	085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DENND2A HSPA12B HMCN2 PIK3CG BSN CPNE5 NKD2	1.00e-06	98	239	7	a74fb790c135bd0d0033df3aca7b789d8b25e361
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DENND2A HSPA12B HMCN2 PIK3CG BSN CPNE5 NKD2	1.00e-06	98	239	7	cb0941481aef9068d7dbce0d1b6cf125f482a98d
ToppCell	Biopsy_Control_(H.)-Epithelial-KRT5-/KRT17+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CRLF1 CAPN13 CYP7B1 BNIP5 COL27A1 MXRA8 FRMPD3 GPSM1 CDH3	1.36e-06	199	239	9	3b1f56c8b40bb36922a31d2d440a8c468a8aa3f1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NES PLXND1 HSPA12B KLF2 HMCN2 ARHGAP31 UTRN PKN3 SHANK3	1.41e-06	200	239	9	93e13937ec74418a697c37d56f57509fb2154780
ToppCell	droplet-Heart-nan-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B PLXND1 NR4A1 KLF2 PHF1 PIR RNF167 PINK1	2.63e-06	161	239	8	eb546d5065ac506405d240f9a1f55f2122d0c368
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	PARD6G PPM1N ATN1 COL27A1 MTOR SIX5 ROBO1 CDH3	4.68e-06	174	239	8	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 NFATC1 SPHK1 CYP7B1 COL27A1 VSTM2B ROBO1 ADGRE5	4.88e-06	175	239	8	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 NFATC1 SPHK1 CYP7B1 COL27A1 VSTM2B ROBO1 ADGRE5	4.88e-06	175	239	8	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	15-Trachea-Epithelial-Secretory_progenitor\|Trachea / Age, Tissue, Lineage and Cell class	CRLF1 PLXND1 SFTPA2 SFTPA1 PPM1N COL27A1 MXRA8 SCUBE2	7.94e-06	187	239	8	be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NES HSPA12B KLF2 PTPN12 ARC UTRN PKN3 SHANK3	8.26e-06	188	239	8	a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NES PLXND1 HSPA12B KLF2 ARHGAP31 UTRN PKN3 SHANK3	8.58e-06	189	239	8	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NES PLXND1 HSPA12B KLF2 ARHGAP31 UTRN PKN3 SHANK3	8.92e-06	190	239	8	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	droplet-Kidney-nan-21m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A1BG NES SPEG ITGA7 ARHGEF17 GDF10 PLEKHH3 RIMBP3	8.92e-06	190	239	8	e04f47705851563515b6a66a2634cf7a574f7bda
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPEG DYSF KLF2 ARHGAP31 PKN3 ATP10D MEGF6 DCHS1	9.27e-06	191	239	8	471205494b91be69926dc8159376132bcea0d9b5
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A GDF10 CYP7B1 MXRA8 SCUBE2 NKD2 TIAM1 MYO16	9.63e-06	192	239	8	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	9.63e-06	192	239	8	28eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.00e-05	193	239	8	6a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.04e-05	194	239	8	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B KLF2 HMCN2 ARHGAP31 UTRN PKN3 SHANK3	1.08e-05	195	239	8	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	droplet-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B HNRNPF KLF2 SFTPA1 PRF1 ARHGEF1 ARHGAP45	1.08e-05	140	239	7	d91ab34d6fded8c39d0f4456ce73281334660f74
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.12e-05	196	239	8	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CRLF1 DACT2 SFTPA1 SDC4 RAP1GAP RASSF7 LLGL2 CDH3	1.12e-05	196	239	8	0a34a0009f479384f1994c6f977f942699a132c8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.12e-05	196	239	8	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.12e-05	196	239	8	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.12e-05	196	239	8	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN SHANK3 ROBO1	1.12e-05	196	239	8	e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.12e-05	196	239	8	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	Healthy/Control-Non-classical_Monocyte\|World / Disease group and Cell class	CDC42EP4 SYT17 NR4A1 PLXNB2 PIK3CG PPM1N MFSD12 TBC1D8	1.16e-05	197	239	8	470784932e1fc3ff69f27cd83f56d85b0c01af63
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN SHANK3 ROBO1	1.16e-05	197	239	8	c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN SHANK3 ROBO1	1.16e-05	197	239	8	2844dbcd0a673ed81c99920aa45858651a00736d
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACO2 TRPS1 PARD6G HNRNPF HNRNPH1 HUWE1 OGDH PAN3	1.20e-05	198	239	8	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid-Microglia\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	NR4A1 PIK3CG TMC8 WAS SIGLEC14 ADGRE5 ARHGAP45 IL6R	1.20e-05	198	239	8	901cd39cb84f1907f2f5d27221979c854bd3b40e
ToppCell	18-Distal-Epithelial-Bud_tip_progenitor\|Distal / Age, Tissue, Lineage and Cell class	CRLF1 DACT2 NR4A1 SFTPA1 SDC4 RAP1GAP RASSF7 SYNE4	1.20e-05	198	239	8	fdd3b428483dbca0fc5b1412446a812e8ad616a9
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACO2 TRPS1 PARD6G HNRNPF HNRNPH1 HUWE1 OGDH PAN3	1.20e-05	198	239	8	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.20e-05	198	239	8	b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	NR4A1 PIK3CG TMC8 WAS SIGLEC14 ADGRE5 ARHGAP45 IL6R	1.20e-05	198	239	8	cc292aa8518d5ef8940e2327f2f07d584a996d90
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.20e-05	198	239	8	953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B DYSF KLF2 ARHGAP31 UTRN PKN3 SHANK3	1.20e-05	198	239	8	8e45551224fbb30c0658ad47dd98335ecf165437
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACO2 TRPS1 PARD6G HNRNPF HNRNPH1 HUWE1 OGDH PAN3	1.25e-05	199	239	8	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DACT2 SFTPA2 ARC UTRN SDC4 FOXP4 LLGL2 KRTCAP3	1.29e-05	200	239	8	c89f3cb36bb14c476d6a392bfd3ded1c8feecfeb
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	NR4A1 CCDC88B KLF2 SLC38A10 AMPD3 WAS ARHGAP45 IL6R	1.29e-05	200	239	8	fe22f7c97f4e37dfa7881d0f1d9245c1237d873b
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DENND2A NR4A1 ITGA7 KLF2 ARC CAD TIAM1 ARMC5	1.29e-05	200	239	8	24e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NES PLXND1 HSPA12B DYSF KLF2 UTRN SHANK3 DCHS1	1.29e-05	200	239	8	dba96cda5f3b780a3d4171b61bc8aaddc1f5d466
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Astrocyte\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	TRPS1 ITGA7 NLGN3 METRN ARC RAP1GAP BCAN SEZ6L	1.29e-05	200	239	8	4fe3b2d80c567c18621bff3341f9a73578c81621
ToppCell	wk_08-11-Epithelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CRLF1 DACT2 UTRN SDC4 COL27A1 RASSF7 KRTCAP3 CDH3	1.29e-05	200	239	8	445fc7995ffc440c6256a6aab0bbf33fb0fea028
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NES PLXND1 HSPA12B DYSF KLF2 UTRN SHANK3 DCHS1	1.29e-05	200	239	8	7a69ad5b6c84f1aebacea5cacb9bc5c63dfd1dac
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OPN4 HSPA12B DYSF ONECUT1 KLF2 ARHGAP31 SHANK3	2.09e-05	155	239	7	5d157478669b609e1f0f0a75afd0112571fc2c46
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2A PARD6G SRPX2 RAP1GAP MXRA8 TIAM1 DCHS1	2.46e-05	159	239	7	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	368C-Myeloid-Dendritic-pDC\|368C / Donor, Lineage, Cell class and subclass (all cells)	TCP10L ABHD15 PFAS CYB561A3 RPAP1 NEK8 ALPK2	3.36e-05	167	239	7	1e2fc1637769405a61f4c7e44945712a1888a299
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG CMPK2 HSPA12B HMCN2 ARHGAP31 UTRN SHANK3	3.63e-05	169	239	7	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_C\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NES NT5C PTPN12 ARHGAP31 UTRN USP29 PRF1	3.77e-05	170	239	7	81341bf4fe090af70b2091b6b2579ed08d76e22d
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZGRF1 PRR12 SRPX2 TELO2 RECQL4 MAP1S PCNT	3.77e-05	170	239	7	b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES CRLF1 EXTL1 PLXND1 RAP1GAP VTN MYO16	4.21e-05	173	239	7	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES CRLF1 EXTL1 PLXND1 RAP1GAP VTN MYO16	4.21e-05	173	239	7	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES CRLF1 EXTL1 PLXND1 TMC8 RAP1GAP MYO16	4.37e-05	174	239	7	4289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES CRLF1 EXTL1 PLXND1 TMC8 RAP1GAP MYO16	4.37e-05	174	239	7	165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD15 TMEM94 ANKRD53 SCAF1 BSN MTOR SEZ6L	4.37e-05	174	239	7	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHK1 COL27A1 PCDHB9 FHOD3 VSTM2B ARID3C SEZ6L	4.70e-05	176	239	7	ef0ff02897104e938c8a632357d8f1a6f014e68a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHK1 COL27A1 PCDHB9 FHOD3 VSTM2B ARID3C SEZ6L	4.70e-05	176	239	7	da0983929fa682a68e536c298a2d7add188b7563
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PRR12 SVIL C16orf86 MAP3K10 IQCG DMGDH MTOR	4.87e-05	177	239	7	36b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA2 SFTPA1 WDR90 RAP1GAP FRMPD1 SYNE4 CDH3	4.87e-05	177	239	7	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SFTPA2 SFTPA1 WDR90 RAP1GAP FRMPD1 SYNE4 CDH3	4.87e-05	177	239	7	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXND1 HSPA12B KLF2 ARHGAP31 UTRN PKN3 SHANK3	5.05e-05	178	239	7	5f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DENND2A SPEG ARHGEF17 PLEKHH3 PPM1N VTN VSTM2B	5.23e-05	179	239	7	f5bb4d3a27d56698473219970e764084096cc582
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DENND2A SPEG ARHGEF17 PLEKHH3 PPM1N VTN VSTM2B	5.23e-05	179	239	7	fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPEG ABCA7 PRR12 FRMPD1 FHOD3 HEXIM2	5.34e-05	123	239	6	87401764a073c1808f214642a9c84299c78f7ec7
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PRR12 SVIL C16orf86 MAP3K10 IQCG DMGDH MTOR	5.42e-05	180	239	7	a682a5d55c612709c9ee9fa4289d6f8bef7fe1af
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDC42EP4 NR4A1 SRPX2 SPHK1 CYP7B1 COL27A1 NKD2	5.61e-05	181	239	7	ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TMEM94 ECD RXRB PPM1N C21orf58 IL6R PINK1	5.81e-05	182	239	7	c98da2db197b1531204e116600ff51891e5c17af
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIGLEC5 NLGN3 METRN SHPK RAP1GAP COL27A1 DUSP15	5.81e-05	182	239	7	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NES PLXND1 DYSF KLF2 ARHGAP31 SHANK3 ROBO1	6.01e-05	183	239	7	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NES PLXND1 DYSF KLF2 ARHGAP31 SHANK3 ROBO1	6.01e-05	183	239	7	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLGN3 AMPD3 RAP1GAP PCDHB9 BCAN VSTM2B SEZ6L	6.22e-05	184	239	7	278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	PODNL1 SRPX2 HMCN2 COL27A1 MXRA8 CGREF1 ROBO1	6.22e-05	184	239	7	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ARHGAP31 PIK3CG CYP7B1 UTRN DMGDH ATP10D ROBO1	6.22e-05	184	239	7	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLGN3 AMPD3 RAP1GAP PCDHB9 BCAN VSTM2B SEZ6L	6.22e-05	184	239	7	8d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma\|TCGA-Prostate / Sample_Type by Project: Shred V9	NECTIN2 HOXB13 RAP1GAP SYNE4 MFSD12 CGREF1 FRMPD3	6.44e-05	185	239	7	9d53e0a92e4f99370be2e4be1dd737630796b1ca
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PODNL1 GDF10 KLF2 DDX43 MXRA8 SCUBE2 NKD2	6.66e-05	186	239	7	4e983de6d2515082f9e555f4f949cec84281c140
ToppCell	Thalamus-Endothelial\|Thalamus / BrainAtlas - Mouse McCarroll V32	NES DYSF KLF2 UTRN ITPRIPL2 SIX5 ADGRE5	6.66e-05	186	239	7	dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NME7 HOXB13 MIA3 RAP1GAP CGREF1 PAN3 IL6R	6.66e-05	186	239	7	32d30f08b20a0a28e38b37bd52ab26d1d43736ce
ToppCell	facs-Heart-LA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD6G ITGA7 ARHGEF17 GDF10 TEX44 PPM1N VTN	6.66e-05	186	239	7	e2ba9f3518d87a44537a57a648df17ab98fbbb39
ToppCell	facs-Heart-LA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARD6G ITGA7 ARHGEF17 GDF10 TEX44 PPM1N VTN	6.66e-05	186	239	7	fda3415222f688ef5cd8de4b0b79daa2493c585f
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ECD YJEFN3 SNAI3 PTPN9 C16orf86 MUS81 PCNT	6.66e-05	186	239	7	927723ad579bbd9947ff525bd501e222d3fa9289
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CRLF1 DACT2 SFTPA1 SDC4 RAP1GAP LLGL2 CDH3	6.66e-05	186	239	7	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	Mesenchymal_cells-Ng2+_MSCs\|Mesenchymal_cells / Lineage and Cell class	PODNL1 NES RAPH1 PARD6G SRPX2 SFTPA1 CGREF1	6.89e-05	187	239	7	e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	HSPA12B KLF2 HMCN2 SHANK3 NKD2 MEGF6 SIX5	7.12e-05	188	239	7	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIGLEC5 NLGN3 METRN SHPK SDC4 COL27A1 NKD2	7.12e-05	188	239	7	921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell	Entopeduncular-Endothelial\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	NES KLF2 UTRN ITPRIPL2 MXRA8 ADGRE5 IL6R	7.12e-05	188	239	7	94774652fd42bad5012356672ffac8b6d2c22d37
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO3A NECTIN2 UTRN FRMPD1 ROBO1 FRMPD3 MYO16	7.36e-05	189	239	7	f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell	Globus_pallidus-Endothelial\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	NES KLF2 UTRN ITPRIPL2 MXRA8 LLGL2 ADGRE5	7.36e-05	189	239	7	ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES PLXND1 ARHGAP31 PCDHB7 BAHD1 SHANK3 DCHS1	7.36e-05	189	239	7	ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DENND2A CYP7B1 COL27A1 NKD2 TIAM1 ROBO1 MYO16	7.61e-05	190	239	7	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A1BG NES SPEG ITGA7 ARHGEF17 GDF10 PLEKHH3	7.61e-05	190	239	7	1803b1e7c36285f9eaabc3c6e9a9752c5908db3d
Drug	Fillalbin [4540-25-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A	BORCS6 CRLF1 ONECUT1 KLF2 KHK DMRT1 UTRN ATN1 RASSF7 ATP10D ADGRE5 POFUT1	1.02e-06	195	237	12	2813_DN
Drug	Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A	MFHAS1 NAB2 CES2 PTPN9 GLI3 UTRN C9orf40 LONP2 DLGAP4 BAHD1 PHF20L1 PHF3	1.20e-06	198	237	12	5334_DN

Protein segments in the cluster

Peptide	Gene	Start	Entry
GPFTPDLAHPVAEVG	ACO2	351	Q99798
GPRVGEALVSHPEVP	ALDH8A1	211	Q9H2A2
LHPLSLDSPDREPGA	ARHGEF1	326	Q92888
PGLRAHLKAEAELPP	C16orf86	116	Q6ZW13
APHVVGSDDLKEPGP	CCDC187	76	A0A096LP49
QPGGQHPLLEAPRED	CCDC88B	481	A6NC98
GEVPEIIPIFLIHRP	ALPK2	2006	Q86TB3
PLPDHRTLQAPEGAL	ARID3C	31	A6NKF2
QAAEPAGPHLPVEDE	ARC	361	Q7LC44
EVKPSELEPLHGVPG	ATN1	951	P54259
APGDVEALAPPVRHL	ADGRE5	311	P48960
GPAPVPAPDLHFLLD	ARMC5	741	Q96C12
QDLPGGPPHFILDDI	CAPN13	66	Q6MZZ7
RTLLLEPEGPAPHAE	ANO9	91	A1A5B4
NFPGVALRHVEPGEP	CGREF1	141	Q99674
SLPDHLPSVGEEPRE	CHKB	86	Q9Y259
REPQGALERPPVDHG	DHTKD1	41	Q96HY7
LDPPHEPLFAGTDRN	DLGAP4	16	Q9Y2H0
THKGAELPREPSEAP	ECD	466	O95905
PEPDGHIISPLLAGF	ATP10D	356	Q9P241
EHPTPDLGPGHVRIK	ABCA7	451	Q8IZY2
HFVLPVAPGPELARE	ABHD15	111	Q6UXT9
LGHPRADTAPPEEGL	AMPD3	181	Q01432
PLITEEGPNLPEIRH	IQCG	121	Q9H095
RHAYPDGRLAEPEKP	MKRN2	346	Q9H000
PRPRGGPHDAELLEV	RASSF7	341	Q02833
GAEHPEPKRPSVDSL	RAPH1	986	Q70E73
PEEPHVPLEQRRGFL	NT5C	31	Q8TCD5
FEGPNDHPEGELPLT	RIMBP3B	846	A6NNM3
FEGPNDHPEGELPLT	RIMBP3C	846	A6NJZ7
GPLEEPEPGELLTHL	ITPKC	301	Q96DU7
GHPDPFDEIILFSLP	PTPN9	256	P43378
HLDSEGEEAPRPIPS	GOLGA8F;	226	Q08AF8
GPRDHLASDPLTPEF	NR4A1	16	P22736
SAPSERLELHVDGPP	A1BG	386	P04217
PDTGPEKLPSLEHRD	ARHGEF17	1996	Q96PE2
IRLGVHPDPTPEHDF	ANKRD53	406	Q8N9V6
PARALHPEEDPEGRQ	BCAN	876	Q96GW7
EDQPPGPAALHVVAR	DCHS1	1556	Q96JQ0
ADRLLLHGPDPVPGA	OTUD1	121	Q5VV17
APEFLPEVPLGQLHD	KIAA0100	1231	Q14667
DPDPHGRPDFGSILK	MAP3K10	341	Q02779
GDALEPGVALPPVHA	GLI3	961	P10071
ELPVAVPSGPFRHEG	ARHGAP45	681	Q92619
PASDAQDLPPLHRIG	LONP2	66	Q86WA8
EDTEGFGVPRHDPLP	MAP1S	811	Q66K74
VLDGHSVPLPEPLEV	LLGL2	781	Q6P1M3
LILDHEVPSLPAFPG	FAAP20	51	Q6NZ36
HAFPGELLSQPRPEG	MFHAS1	996	Q9Y4C4
REDGRPELPPQAHGL	METRN	151	Q9UJH8
SPPLLHRAPEDEAAG	MYO16	1456	Q9Y6X6
FEEGLLDRCPAPGPH	NAB2	491	Q15742
TQDPGHLPPDVRETL	GPSM1	171	Q86YR5
GRPLEPRPGVHLSAD	HMCN2	2116	Q8NDA2
ILSEPEPEDPALVGH	KATNIP	211	O60303
EPEDPALVGHPRHDR	KATNIP	216	O60303
IEEGDLPEHKRPSAP	MESD	76	Q14696
PRRHGHEPAEDSDPL	MCM3AP	301	O60318
EPGAEPHRATPAELR	BSN	1836	Q9UPA5
NELPGLDERPPRAHA	GDF10	301	P55107
EPLLEVKPTHSRPEG	FAM90A22	221	A8MWA6
LFGESPPHPARVEGE	PLXNB2	556	O15031
PDVLPSRLHPEGLGH	PINK1	296	Q9BXM7
PEIHAIEPLSGPLDG	PLXND1	891	Q9Y4D7
LDGHELPPPIAFDVE	NXF1	351	Q9UBU9
TPPLHPDFKRALGDL	PRF1	186	P14222
LLPGPPFARELHIEI	PEX6	311	Q13608
PGVVDGVFLPRHPQE	CES2	311	O00748
IAGEPLREPVIQHGP	PIR	241	O00625
RHLPGHVLQELGPEP	PPM1N	116	Q8N819
HVLQELGPEPSEPEG	PPM1N	121	Q8N819
VSHEPVPAPADLLGG	ONECUT1	16	Q9UBC0
ESPTAGPRLLPEVHE	NFATC1	886	O95644
GPRLLPEVHEDGSPN	NFATC1	891	O95644
DAGLPRPVQLDETHP	NEK8	651	Q86SG6
LDELVARSPGPDGHP	PHRF1	6	Q9P1Y6
EGHPESPEPKEQRGL	NES	1011	P48681
LHPLEPDEVEYEPRG	LNPEP	36	Q9UIQ6
ELPLGPEPFLAAHQD	LRRC37B	106	Q96QE4
PGEVLFRLHREPDLP	GDPGP1	131	Q6ZNW5
LPLSHDDVGAPVEPL	FOXP4	601	Q8IVH2
PLDTDVLVPGAPERH	KMT2B	1821	Q9UMN6
PLNPVRVHIEIGPDG	HNRNPH1	311	P31943
FVPGRHPPEKLLVRD	HSPA12B	551	Q96MM6
EPLHRPIESPGGSVL	HUWE1	856	Q7Z6Z7
VEHEVVRDLPPTPAG	NKD2	406	Q969F2
HDAALEPVVPDPQGD	PCNT	1986	O95613
VEPGVHLGRPDVLPQ	PIP5K1A	501	Q99755
HRDVLPDKPAPGAVN	GTSE1	256	Q9NYZ3
EEPGIPAILNESHPE	HEMGN	461	Q9BXL5
PRHSLALPPGGVEEH	PARD6G	356	Q9BYG4
PEDAEDGPPELLFIH	RBBP4	356	Q09028
SLHPVLREPPDHGEL	POU3F4	161	P49335
IIESLHRGPPGAEPH	OTOP2	421	Q7RTS6
PVPGSPEHVGEDLTR	PRR35	396	P0CG20
EHLRGPLPPSADDNL	NPIPB11	501	E5RHQ5
EDLEAKAPPRPQGHE	OPN4	446	Q9UHM6
PPPVAGLEDAAFPHL	PODNL1	21	Q6PEZ8
EGPLPRQHAGLLPES	PAN3	601	Q58A45
EAGPPHDTLRLTALP	NLGN3	776	Q9NZ94
LPGTHFQRVIPEDGP	OGDH	876	Q02218
PEGPFPRHLVDLSGT	PCDHB7	726	Q9Y5E2
APRPHLGEFEADPRG	CMPK2	156	Q5EBM0
EEAELQLPGHSGPPV	FKBPL	171	Q9UIM3
RPAGTVHLLVDVPPE	IL6R	101	P08887
ASVPEPEFPGHVILE	HEATR5B	1326	Q9P2D3
LGLPEELVSRHPFPG	GMPS	426	P49915
ELVSRHPFPGPGLAI	GMPS	431	P49915
DLPGTEEHQRARGPP	KCNB2	636	Q92953
QHPEPLEAAGEPALR	BNIP5	131	P0C671
HRPEREALENEPGPQ	BORCS6	71	Q96GS4
LLLDRPEGAHAAPQP	DACT2	516	Q5SW24
RVHPSDLEGREPTPE	DENND2A	216	Q9ULE3
PEGLHLEPGNEDRPD	C21orf58	116	P58505
LEPLALHPPLAFEDG	FRMPD1	751	Q5SYB0
LLSPVPEDKGPGHTR	FRMPD3	926	Q5JV73
AAERLLGPPPHVAAG	DUSP15	196	Q9H1R2
VIPPGVPDAHPREGD	CCDC40	226	Q4G0X9
VLDVDLGHREAPGPP	FHOD3	816	Q2V2M9
PDLPSLPSHALEDEG	CDC42EP4	271	Q9H3Q1
PVAAPHEEGLLLAPS	BAHD1	406	Q8TBE0
VLLPFHRDPALDPGG	COL27A1	181	Q8IZC6
GISGHPEPRHDALIP	HOXC13	196	P31276
LHGEPPFDLIELDPN	DMGDH	416	Q9UI17
GQPHPEALGFPLELR	MIDEAS	391	Q6PJG2
RPEPPETGESHLRLE	FAM47A	326	Q5JRC9
DGKLLHSDAFPPPRV	KHK	236	P50053
DLVAIFPPVLHGDPE	CYP7B1	391	O75881
PRREGPDAHPILAAD	ITGA7	1151	Q13683
PDAHPILAADGHPEL	ITGA7	1156	Q13683
PEPGILTDRQPLLHD	CYB561A3	226	Q8NBI2
EGPEGSEREHRPPEK	FAM102A	276	Q5T9C2
EREDHGLETGDPPLP	C9orf40	86	Q8IXQ3
AHLLFPPPREEGLGF	FAM83H	326	Q6ZRV2
TLGAPGEPRHDSLLP	HOXB13	151	Q92826
DPPPDVHVSRVGGLE	CRLF1	236	O75462
VKEPGPEAGLHTAPL	PIWIL3	76	Q7Z3Z3
GELEPERPELPGLHK	SAMD15	16	Q9P1V8
PLVPLDNHIPERAGS	SDC4	81	P31431
ELFPEGLRPALPEKH	SCUBE2	506	Q9NQ36
DIVEEEPARPPGHGI	SCAPER	511	Q9BY12
APPETEIVPLVLRGH	SCAP	761	Q12770
GIAVPVGEAHRHEPP	SLC38A10	486	Q9HBR0
EEIEAGRIPNPHLGP	DYSF	1731	O75923
GRIPNPHLGPVEERL	DYSF	1736	O75923
HAEEPGEHTPLLAPA	MFSD12	246	Q6NUT3
RPPEAVAAGHEELPL	DDX43	56	Q9NXZ2
LTLIDVNDHGPVPEP	CDH3	536	P22223
GPADPEIARHLRPGT	NME7	326	Q9Y5B8
AKLPPDGRVSHEFPL	CPNE5	386	Q9HCH3
AQEEELGISHPIPLP	DMRT1	126	Q9Y5R6
LLDPLVPLDEGPGHT	KRTCAP3	136	Q53RY4
PVEPDLAVAGIHSLP	PIAS2	91	O75928
SPEPGPELLAEELQH	PKN3	171	Q6P5Z2
TPHLPPHRGGKEIEE	PCDHB9	771	Q9Y5E1
PEVPDVAHLPLEKLG	PHF20L1	456	A8MW92
PAVHLGDGVFLVAPP	ITPRIPL2	311	Q3MIP1
ALPGAPAQFPVLEEH	POFUT1	191	Q9H488
LLGVDPSRQLDHPLP	MTOR	1676	P42345
DSGPPDRSPLELHIG	PHF1	466	O43189
QALGLHLPDPPLESE	MEA1	101	Q16626
LDGELPFVRPLPHIA	MEGF6	461	O75095
EHHLLPSPEGEIAPA	CWH43	516	Q9H720
PLNPVRVHIEIGPDG	HNRNPF	311	P52597
PEEERHPGLSNLATP	SZT2	1671	Q5T011
DQHLRRGLPVGSPPE	UTRN	3286	P46939
VPGPVGEPADSDKRH	CARS2	211	Q9HA77
IPDHLRPEYGLEAAP	UVSSA	421	Q2YD98
APERGSPGKEHPEER	SEZ6L	51	Q9BYH1
HPEGLSPDGHELPFL	PLEKHH3	501	Q7Z736
APGPAVHRPVDADGL	REPS1	596	Q96D71
LERANPPITHLGDEP	SVIL	1001	O95425
IEARDLPPPISHDGS	SYT17	206	Q9BSW7
LNHPPGAPREADIVG	SYNE4	16	Q8N205
PDRAVLGTIHPDPEI	MIA3	761	Q5JRA6
LEARDPKEGTHPEDP	TCP10L	6	Q8TDR4
NAGPPSHIIGDEEIP	LRRC41	571	Q15345
FEGPNDHPEGELPLT	RIMBP3	846	Q9UFD9
LAVAEEPDLHGPAPV	RECQL4	656	O94761
RDPEEPNLDVPHGIS	HEXIM2	151	Q96MH2
PRPDRLPLDEKGHVT	PTPN12	521	Q05209
EGEPRDHPASERTPL	RNF167	296	Q9H6Y7
EDGEPPRRHEQFIPI	PRRC2C	1386	Q9Y520
PSVHEVLGREGPFPL	RAP1GAP	31	P47736
HTVLRLPDPDPEGLL	SIX5	691	Q8N196
PDIHFLEPLESGRPT	SIGLEC5	146	O15389
GFPVHLLPDIAEPGS	SHPK	221	Q9UHJ6
EVVSARIHPEGPPLK	TELO2	411	Q9Y4R8
PPGLPAHLDEELQAT	SFTPA2	96	Q8IWL1
PVDPIRAAGLHPTAE	SUPV3L1	501	Q8IYB8
LGRHSDDGPVLPLDP	KIF25	76	Q9UIL4
VHLLEPATRDGAPQP	PRR12	821	Q9ULL5
RPGFDVALPFLPEAH	EXTL1	191	Q92935
PPGLPAHLDEELQAT	SFTPA1	96	Q8IWL2
PEDVKPPVLGVRGLH	RXRB	176	P28702
PTLGPDRHGAPEKLL	SNAI3	126	Q3KNW1
PEESQDPAALHELGP	SSH1	856	Q8WYL5
LPGERPDTIHLEGLP	AKAP17A	141	Q02040
PDDPGFGPHQRLEKL	ADAM17	21	P78536
PKGLVDREPPEELVH	ADAM17	196	P78536
RHIGGPESEPPQALR	CLCC1	361	Q96S66
KHQPTPDPEGDRVRA	PIK3CG	531	P48736
SPGPHEVALGRRPLD	TEX44	246	Q53QW1
DIPLDLAIKHSRPGP	TRPS1	1161	Q9UHF7
PGALLEDVAHNPRPR	SUN5	11	Q8TC36
SGRIIRELPGVHPEP	WDR90	916	Q96KV7
HLVEDLSRLLPEPGP	TMC8	641	Q8IU68
PHFTELLLPLDPLEG	TPRX1	351	Q8N7U7
EARLEDRAHLPGPAP	TICRR	81	Q7Z2Z1
HLVADVDPGEGRPPI	TICRR	391	Q7Z2Z1
LLESPPHRVDGPADL	TIAM1	936	Q13009
PHRVDGPADLGESPL	TIAM1	941	Q13009
PVQLLEHGPTLEEAP	SPEG	1376	Q15772
PPEAAHFLFGEPTLR	SLC2A4RG	176	Q9NR83
VHSPDADRPGPLFVD	SHANK3	1131	Q9BYB0
DEHIVLEPGDLFPPF	TMEM94	206	Q12767
PEPGSHFPEGEHVIR	SRPX2	226	O60687
PAPRAPEGDDFLSLH	SCAF1	436	Q9H7N4
PPRELLHELALSVPG	VSTM2B	71	A6NLU5
GEHPPDLDLPENLVR	PFAS	876	O15067
RFLDHIKNEDSPGPP	TBC1D8	726	O95759
EEPHEAGEQLPPFLL	UBE2O	451	Q9C0C9
VPHLEDGVPRPGERS	ZNF646	1426	O15015
ANEERRGGLPPLPLH	WAS	166	P42768
GPDPSEAPEERHFLR	YJEFN3	6	A6XGL0
PPPGVRKLDAQEHTE	USP29	751	Q9HBJ7
LVPFDGPGLELHRPN	PHF3	1326	Q92576
TFEEPPRDPRHLGAQ	SORBS3	166	O60504
PSGHAPGQDRIALEP	RPS6KL1	266	Q9Y6S9
REKPEPEQGLHPDLA	ARHGAP31	736	Q2M1Z3
PEDVERGNDHGTPIP	ROBO1	31	Q9Y6N7
PPPDLARHDVIKGLL	RPAP1	526	Q9BWH6
PLETPLGHILGREPT	UBXN1	51	Q04323
HRASDPGLPAEEPKE	CAD	1856	P27708
PKPALISHLERGEAP	ZNF621	56	Q6ZSS3
HISEPEDLGKIRSPP	ZGRF1	781	Q86YA3
EDLGKIRSPPPDHVE	ZGRF1	786	Q86YA3
EEPLPNPGSFDELHR	TOMM40L	21	Q969M1
QGPVDAHLVPLEEPV	SPHK1	231	Q9NYA1
HVAAEPQPGPSRALE	ZNF275	151	Q9NSD4
ELERLHAGPEPQALP	UNK	716	Q9C0B0
PVIDGHFLREPPARA	TG	2481	P01266
KPEGIDSRPETLHPG	VTN	131	P04004
PDIHFLEPLESGRPT	SIGLEC14	146	Q08ET2
LPDLSEVGPFHGQPL	ULK1	661	O75385
DPEPLPAHRQALGER	UBR5	2386	O95071
SIRDGIHGPLLEPFV	TYK2	446	P29597
LRPELDAPLGPALHG	KLF2	96	Q9Y5W3
PESILGEEAPRFPHL	KMT2D	4711	O14686
PPGVPHDRADRLLDL	MXRA8	211	Q9BRK3
IELGDGDPPLADLHP	MYO3A	221	Q8NEV4
NPRDPANPGELVLDH	MUS81	316	Q96NY9
ELPTLEERSGPLHPG	NECTIN2	456	Q92692