Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1A CACNA1B SEC61A2 SLC22A18 SCN11A AQP10 SLC8A1 SLC22A25 ABCB7 SLC7A3 ABCB9 SLC26A7 SCN2A SLC22A5 SCN4A ATP2C2 SCN5A SCN9A LRRC8A SLC5A9 SERINC3 SLC46A1 SLC25A29 SLC39A14 ATP1A4 FXYD3 SLC30A4 SEC61A1 ATP13A2 SLC23A2 ABCA7 SLC23A1 MFSD1 SLC16A12 SLC39A8 SLC22A12

2.79e-2111809036GO:0022857
GeneOntologyMolecularFunctiontransporter activity

CACNA1A CACNA1B SEC61A2 SLC22A18 SCN11A AQP10 SLC8A1 SLC22A25 ABCB7 SLC7A3 ABCB9 SLC26A7 SCN2A SLC22A5 SCN4A ATP2C2 SCN5A SCN9A LRRC8A SLC5A9 SERINC3 SLC46A1 SLC25A29 SLC39A14 ATP1A4 FXYD3 SLC30A4 SEC61A1 ATP13A2 SLC23A2 ABCA7 SLC23A1 MFSD1 SLC16A12 SLC39A8 SLC22A12

5.18e-2012899036GO:0005215
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC22A18 SLC8A1 SLC22A25 ABCB7 ABCB9 SLC26A7 SLC22A5 ATP2C2 SLC5A9 SLC46A1 SLC39A14 ATP1A4 SLC30A4 ATP13A2 SLC23A2 ABCA7 SLC23A1 MFSD1 SLC16A12 SLC39A8

2.69e-144779020GO:0022804
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1A CACNA1B SCN11A SLC8A1 SLC26A7 SCN2A SCN4A ATP2C2 SCN5A SCN9A LRRC8A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FXYD3 SLC30A4 SEC61A1 ATP13A2 SLC23A2 SLC23A1 SLC39A8

4.67e-127939022GO:0015075
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1A CACNA1B SCN11A AQP10 SLC8A1 SLC26A7 SCN2A SCN4A ATP2C2 SCN5A SCN9A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FXYD3 SLC30A4 SEC61A1 SLC23A2 SLC23A1 SLC39A8

1.60e-117589021GO:0015318
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1A CACNA1B SCN11A SLC8A1 SCN2A SCN4A ATP2C2 SCN5A SCN9A SLC5A9 SLC39A14 ATP1A4 SLC30A4 SEC61A1 SLC23A2 SLC23A1 SLC39A8

2.55e-114659017GO:0046873
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC22A18 SLC8A1 SLC22A25 SLC26A7 SLC22A5 SLC5A9 SLC46A1 SLC39A14 SLC30A4 SLC23A2 SLC23A1 MFSD1 SLC16A12 SLC39A8

6.00e-112969014GO:0015291
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1A CACNA1B SCN11A SLC8A1 SCN2A SCN4A ATP2C2 SCN5A SCN9A SLC5A9 SLC46A1 SLC39A14 ATP1A4 SLC30A4 SEC61A1 ATP13A2 SLC23A2 SLC23A1 SLC39A8

1.00e-106649019GO:0008324
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1A CACNA1B SCN11A SLC8A1 SCN2A SCN4A ATP2C2 SCN5A SCN9A SLC5A9 SLC46A1 SLC39A14 ATP1A4 SLC30A4 SEC61A1 SLC23A2 SLC23A1 SLC39A8

3.19e-106279018GO:0022890
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC22A18 SLC22A25 SLC7A3 SLC26A7 LRRC8A SERINC3 SLC46A1 SLC25A29 SLC39A14 SLC23A2 SLC23A1 SLC16A12 SLC39A8

6.71e-102939013GO:0008514
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SLC8A1 SCN2A SCN4A SCN5A SCN9A SLC5A9 ATP1A4 SLC23A2 SLC23A1

5.16e-091719010GO:0015081
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A SCN2A SCN4A SCN5A SCN9A

1.01e-0726905GO:0005248
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC8A1 SLC26A7 ATP2C2 SLC5A9 SLC46A1 SLC39A14 ATP1A4 ATP13A2 SLC23A2 SLC23A1 SLC39A8

1.10e-073019011GO:0022853
GeneOntologyMolecularFunctionG protein-coupled receptor activity

VN1R3 OR3A2 PROKR1 TAS2R42 TAS2R4 ADRA1D OR10J3 GPR82 TAAR2 HRH4 TAAR9 ADGRV1 OR8D4 TAS2R50 OR2T11 BDKRB2 TAAR6

3.69e-078849017GO:0004930
GeneOntologyMolecularFunctionsymporter activity

SLC22A18 SLC22A5 SLC5A9 SLC46A1 SLC39A14 SLC23A2 SLC23A1 SLC39A8

3.87e-07150908GO:0015293
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC22A25 SLC7A3 SLC26A7 SERINC3 SLC46A1 SLC25A29 SLC23A2 SLC23A1 SLC16A12

3.97e-07207909GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC22A25 SLC7A3 SLC26A7 SERINC3 SLC46A1 SLC25A29 SLC23A2 SLC23A1 SLC16A12

4.14e-07208909GO:0005342
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

ADRA1D TAAR2 HRH4 TAAR9 TAAR6

1.10e-0641905GO:0008227
GeneOntologyMolecularFunctionsodium channel activity

SCN11A SCN2A SCN4A SCN5A SCN9A

3.66e-0652905GO:0005272
GeneOntologyMolecularFunctionchannel activity

CACNA1A CACNA1B SCN11A AQP10 SLC26A7 SCN2A SCN4A SCN5A SCN9A LRRC8A FXYD3 SEC61A1

4.09e-065259012GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1A CACNA1B SCN11A AQP10 SLC26A7 SCN2A SCN4A SCN5A SCN9A LRRC8A FXYD3 SEC61A1

4.17e-065269012GO:0022803
GeneOntologyMolecularFunctiontrace-amine receptor activity

TAAR2 TAAR9 TAAR6

4.88e-068903GO:0001594
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A CACNA1B SCN11A SLC26A7 SCN2A SCN4A SCN5A SCN9A LRRC8A FXYD3 SEC61A1

6.82e-064599011GO:0005216
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCB7 ABCB9 ATP2C2 ATP1A4 ATP13A2 ABCA7

9.88e-06109906GO:0042626
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A9 SLC46A1 SLC39A14 SLC23A2 SLC23A1 SLC39A8

1.63e-05119906GO:0015294
GeneOntologyMolecularFunctionL-ascorbic acid transmembrane transporter activity

SLC23A2 SLC23A1

2.01e-052902GO:0015229
GeneOntologyMolecularFunctionL-ascorbate:sodium symporter activity

SLC23A2 SLC23A1

2.01e-052902GO:0008520
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

VN1R3 OR3A2 PROKR1 TAS2R42 TAS2R4 ADRA1D OR10J3 GPR82 TAAR2 HRH4 TAAR9 ADGRV1 OR8D4 TAS2R50 OR2T11 ABCA7 BDKRB2 TAAR6

2.85e-0513539018GO:0004888
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

AQP10 SLC5A9 SLC23A2 SLC23A1

3.79e-0542904GO:0015144
GeneOntologyMolecularFunctionamide transmembrane transporter activity

AQP10 ABCB9 SLC46A1 MFSD1

3.79e-0542904GO:0042887
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

ATP2C2 SLC39A14 SLC30A4 SLC39A8

4.56e-0544904GO:0046915
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC5A9 SLC23A2 SLC23A1

5.75e-0517903GO:0005402
GeneOntologyMolecularFunctionABC-type transporter activity

ABCB7 ABCB9 ATP13A2 ABCA7

7.00e-0549904GO:0140359
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCB7 ABCB9 ATP2C2 ATP1A4 ATP13A2 ABCA7

1.55e-04178906GO:0015399
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A SEC61A1

1.59e-04343908GO:0005261
GeneOntologyMolecularFunctionzinc ion transmembrane transporter activity

SLC39A14 SLC30A4 SLC39A8

1.67e-0424903GO:0005385
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC5A9 SLC23A2 SLC23A1

2.39e-0427903GO:0015145
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R42 TAS2R4 TAS2R50

2.39e-0427903GO:0033038
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC5A9 SLC23A2 SLC23A1

2.97e-0429903GO:0051119
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC26A7 SLC39A14 SLC39A8

4.00e-0432903GO:0015106
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC22A5 SLC46A1 SLC16A12

4.38e-0433903GO:0072349
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R42 TAS2R4 TAS2R50

4.38e-0433903GO:0008527
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC22A18 SLC22A5 SLC46A1

4.79e-0434903GO:0042910
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC7A3 SLC22A5 SERINC3 SLC25A29

5.40e-0483904GO:0015101
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP2C2 ATP1A4 ATP13A2

5.68e-0436903GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP2C2 ATP1A4 ATP13A2

5.68e-0436903GO:0015662
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC46A1 SLC23A2 SLC23A1

5.68e-0436903GO:0090482
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A CACNA1B SLC8A1 ATP2C2 SEC61A1

6.07e-04151905GO:0015085
GeneOntologyMolecularFunctionheme transmembrane transporter activity

ABCB7 SLC46A1

7.09e-049902GO:0015232
GeneOntologyMolecularFunctionurate transmembrane transporter activity

SLC23A1 SLC22A12

7.09e-049902GO:0015143
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1B

7.09e-049902GO:0099511
GeneOntologyMolecularFunctionsalt transmembrane transporter activity

SLC23A1 SLC22A12

7.09e-049902GO:1901702
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1B

7.09e-049902GO:0099626
GeneOntologyMolecularFunctionL-lysine transmembrane transporter activity

SLC7A3 SLC25A29

7.09e-049902GO:0015189
GeneOntologyMolecularFunctionmanganese ion transmembrane transporter activity

ATP2C2 SLC39A14

8.83e-0410902GO:0005384
GeneOntologyMolecularFunctionuniporter activity

MFSD1 SLC16A12

8.83e-0410902GO:0015292
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC7A3 SLC25A29

1.52e-0313902GO:0061459
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC39A14 SLC39A8

1.52e-0313902GO:0140410
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1B

1.76e-0314902GO:0008331
GeneOntologyMolecularFunctionsodium ion binding

SCN2A SCN9A

1.76e-0314902GO:0031402
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC22A5 SLC25A29

2.03e-0315902GO:0015651
GeneOntologyMolecularFunctionribosome binding

SEC61A2 MTOR SPCS1 SEC61A1

2.13e-03120904GO:0043022
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

ABCB9 MFSD1

2.31e-0316902GO:0035673
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP2C2 ATP1A4 ATP13A2

2.76e-0362903GO:0019829
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC7A3 SLC25A29

3.62e-0320902GO:0015174
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC7A3 SERINC3 SLC25A29

4.06e-0371903GO:0015179
GeneOntologyMolecularFunctionankyrin binding

SLC8A1 SCN5A

4.78e-0323902GO:0030506
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC26A7 LRRC8A SLC39A14 FXYD3

4.85e-03151904GO:0008509
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A9 SLC23A2 SLC23A1

5.86e-0381903GO:0015370
GeneOntologyMolecularFunctionalkali metal ion binding

SCN2A SCN9A

6.09e-0326902GO:0031420
GeneOntologyMolecularFunctionprotein transmembrane transporter activity

SEC61A2 SEC61A1

7.04e-0328902GO:0008320
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC26A7 SLC46A1

8.58e-0331902GO:0005310
GeneOntologyMolecularFunctionmacromolecule transmembrane transporter activity

SEC61A2 SEC61A1

1.03e-0234902GO:0022884
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC23A2 SLC23A1

1.09e-0235902GO:0005343
GeneOntologyMolecularFunctionamyloid-beta binding

CACNA1A CACNA1B C1QA

1.10e-02102903GO:0001540
GeneOntologyMolecularFunctionmonoatomic anion channel activity

SLC26A7 LRRC8A FXYD3

1.13e-02103903GO:0005253
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1A CACNA1B SLC22A18 SCN11A SLC8A1 SLC22A25 ABCB7 SLC26A7 MTOR SCN2A SLC22A5 SCN4A ATP2C2 SCN5A SCN9A LRRC8A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FASLG FXYD3 SLC30A4 SEC61A1 ATP13A2 SLC23A2 SLC23A1 SLC39A8 SLC22A12

4.96e-1313749129GO:0006811
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1A CACNA1B SCN11A SLC8A1 ABCB7 SLC26A7 MTOR SCN2A SCN4A ATP2C2 SCN5A SCN9A LRRC8A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FASLG FXYD3 SLC30A4 SEC61A1 SLC23A2 SLC23A1 SLC39A8

8.25e-1210179124GO:0098660
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1A CACNA1B SCN11A SLC8A1 ABCB7 SLC26A7 MTOR SCN2A SCN4A ATP2C2 SCN5A SCN9A LRRC8A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FASLG FXYD3 SLC30A4 SEC61A1 ATP13A2 SLC23A2 SLC23A1 SLC39A8

8.32e-1211159125GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1A CACNA1B SCN11A SLC8A1 ABCB7 SCN2A SCN4A ATP2C2 SCN5A SCN9A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FASLG FXYD3 SLC30A4 SEC61A1 ATP13A2 SLC23A2 SLC23A1 SLC39A8

8.92e-119429122GO:0098655
GeneOntologyBiologicalProcessmetal ion transport

CACNA1A CACNA1B SCN11A SLC8A1 ABCB7 SCN2A SLC22A5 SCN4A ATP2C2 SCN5A SCN9A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FASLG FXYD3 SLC30A4 SEC61A1 SLC23A2 SLC23A1 SLC39A8

2.78e-1010009122GO:0030001
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1A CACNA1B SCN11A SLC8A1 ABCB7 SCN2A SCN4A ATP2C2 SCN5A SCN9A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FASLG FXYD3 SLC30A4 SEC61A1 SLC23A2 SLC23A1 SLC39A8

4.09e-109229121GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1A CACNA1B SCN11A SLC8A1 ABCB7 SCN2A SLC22A5 SCN4A ATP2C2 SCN5A SCN9A SLC5A9 SLC46A1 SLC39A14 ATP1A4 FASLG FXYD3 SLC30A4 SEC61A1 ATP13A2 SLC23A2 SLC23A1 SLC39A8

7.28e-1011579123GO:0006812
GeneOntologyBiologicalProcessorganic anion transport

CACNA1A SLC22A25 SLC7A3 SLC26A7 LRRC8A PLA2G2A SERINC3 SLC46A1 SLC25A29 SLC39A14 SLC23A2 SLC23A1 BDKRB2 SLC16A12 SLC39A8 SLC22A12

8.41e-105159116GO:0015711
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A SLC8A1 SCN2A SCN4A SCN5A SCN9A SLC5A9 ATP1A4 FXYD3 SLC23A2 SLC23A1

1.97e-092089111GO:0035725
GeneOntologyBiologicalProcesssodium ion transport

SCN11A SLC8A1 SCN2A SLC22A5 SCN4A SCN5A SCN9A SLC5A9 ATP1A4 FXYD3 SLC23A2 SLC23A1

3.07e-092759112GO:0006814
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN11A SLC8A1 SCN2A SCN4A SCN5A SCN9A

1.09e-0836916GO:0086010
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1A CACNA1B SLC8A1 SLC7A3 SCN5A LRRC8A SLC46A1 SLC39A14 ATP1A4 SLC39A8

7.14e-082309110GO:0098739
GeneOntologyBiologicalProcesscirculatory system process

CACNA1B SCN11A SLC8A1 ADRA1D SLC7A3 MTOR SCN2A SLC22A5 SCN4A SCN5A SCN9A EXT2 ATP1A4 SLC23A2 BDKRB2 SLC16A12

1.19e-077339116GO:0003013
GeneOntologyBiologicalProcesscarboxylic acid transport

CACNA1A SLC7A3 SLC26A7 LRRC8A PLA2G2A SERINC3 SLC46A1 SLC25A29 SLC23A2 SLC23A1 BDKRB2 SLC16A12

2.48e-074109112GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

CACNA1A SLC7A3 SLC26A7 LRRC8A PLA2G2A SERINC3 SLC46A1 SLC25A29 SLC23A2 SLC23A1 BDKRB2 SLC16A12

2.62e-074129112GO:0015849
GeneOntologyBiologicalProcessneuronal action potential

SCN11A MTOR SCN2A SCN4A SCN5A SCN9A

3.46e-0763916GO:0019228
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC7A3 SLC26A7 LRRC8A SLC46A1 SLC25A29 SLC23A2 SLC23A1 SLC16A12

6.24e-07163918GO:1905039
GeneOntologyBiologicalProcesstransmission of nerve impulse

CACNA1A SCN11A MTOR SCN2A SCN4A SCN5A SCN9A

6.40e-07112917GO:0019226
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC7A3 SLC26A7 LRRC8A SLC46A1 SLC25A29 SLC23A2 SLC23A1 SLC16A12

7.50e-07167918GO:1903825
GeneOntologyBiologicalProcessheart contraction

CACNA1B SCN11A SLC8A1 ADRA1D MTOR SCN2A SCN4A SCN5A SCN9A EXT2

7.80e-072989110GO:0060047
GeneOntologyBiologicalProcessmembrane depolarization

CACNA1A SCN11A SLC8A1 SCN2A SCN4A SCN5A SCN9A

1.08e-06121917GO:0051899
GeneOntologyBiologicalProcessheart process

CACNA1B SCN11A SLC8A1 ADRA1D MTOR SCN2A SCN4A SCN5A SCN9A EXT2

1.08e-063099110GO:0003015
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN11A SLC8A1 SCN2A SCN4A SCN5A SCN9A

2.37e-0687916GO:0086001
GeneOntologyBiologicalProcessresponse to pain

CACNA1A CACNA1B SCN11A MTOR SCN9A

2.99e-0651915GO:0048265
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1A CACNA1B SLC8A1 SCN5A SLC39A14 ATP1A4 SLC39A8

3.16e-06142917GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1A CACNA1B SLC8A1 SCN5A SLC39A14 ATP1A4 SLC39A8

3.16e-06142917GO:0098659
GeneOntologyBiologicalProcessorganic cation transport

CACNA1A SLC22A18 SLC7A3 SLC22A5 SCN4A SERINC3 SLC25A29

3.63e-06145917GO:0015695
GeneOntologyBiologicalProcessresponse to toxic substance

SLC22A18 SCN11A AQP10 SLC22A5 SCN9A SLC30A4 SLC23A1 SLC39A8 CLDN1

5.28e-06289919GO:0009636
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN11A SCN2A SCN4A SCN5A SCN9A

7.94e-0662915GO:0086002
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

VN1R3 OR3A2 PROKR1 TAS2R42 TAS2R4 SCN11A ADRA1D OR10J3 GPR82 TAAR2 HRH4 TAAR9 ADGRV1 SLC39A14 OR8D4 TAS2R50 OR2T11 BDKRB2 TAAR6

8.79e-0613959119GO:0007186
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN11A SLC8A1 MTOR SCN2A SCN4A SCN5A SCN9A

9.20e-06167917GO:0060048
GeneOntologyBiologicalProcesstransition metal ion transport

ABCB7 ATP2C2 SLC46A1 SLC39A14 SLC30A4 SLC39A8

1.08e-05113916GO:0000041
GeneOntologyBiologicalProcessbehavioral response to pain

CACNA1A SCN11A MTOR SCN9A

1.16e-0532914GO:0048266
GeneOntologyBiologicalProcessmanganese ion transmembrane transport

ATP2C2 SLC39A14 SLC39A8

1.78e-0512913GO:0071421
GeneOntologyBiologicalProcessintracellular iron ion homeostasis

ABCB7 SLC46A1 SLC39A14 ATP13A2 SLC39A8

2.45e-0578915GO:0006879
GeneOntologyBiologicalProcessblood circulation

CACNA1B SCN11A SLC8A1 ADRA1D MTOR SCN2A SCN4A SCN5A SCN9A EXT2 SLC23A2 BDKRB2

2.73e-056489112GO:0008015
GeneOntologyBiologicalProcessmanganese ion transport

ATP2C2 SLC39A14 SLC39A8

2.92e-0514913GO:0006828
GeneOntologyBiologicalProcessaction potential

SCN11A SLC8A1 MTOR SCN2A SCN4A SCN5A SCN9A

3.05e-05201917GO:0001508
GeneOntologyBiologicalProcessmodified amino acid transport

SLC22A5 SLC46A1 SLC25A29 SLC16A12

4.20e-0544914GO:0072337
GeneOntologyBiologicalProcessstriated muscle contraction

SCN11A SLC8A1 MTOR SCN2A SCN4A SCN5A SCN9A

4.96e-05217917GO:0006941
GeneOntologyBiologicalProcessexport across plasma membrane

SLC22A18 SLC8A1 SLC22A5 ATP1A4 SLC30A4

5.16e-0591915GO:0140115
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN11A SCN2A SCN4A SCN5A SCN9A

5.73e-0593915GO:0086003
GeneOntologyBiologicalProcessL-ascorbic acid transmembrane transport

SLC23A2 SLC23A1

5.76e-053912GO:0015882
GeneOntologyBiologicalProcessinorganic ion homeostasis

CACNA1A SLC8A1 ABCB7 ATP2C2 SLC46A1 EXT2 SLC39A14 ATP1A4 FASLG ATP13A2 SLC39A8

9.13e-056229111GO:0098771
GeneOntologyBiologicalProcessmanganese ion homeostasis

SLC39A14 SLC39A8

1.15e-044912GO:0055071
GeneOntologyBiologicalProcessvitamin transmembrane transport

SLC46A1 SLC23A2 SLC23A1

1.38e-0423913GO:0035461
GeneOntologyBiologicalProcessvascular process in circulatory system

SLC8A1 ADRA1D SLC7A3 SLC22A5 EXT2 ATP1A4 BDKRB2 SLC16A12

1.41e-04344918GO:0003018
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC22A18 SLC26A7 MTOR LRRC8A SLC39A14 FXYD3

1.60e-04183916GO:0006820
GeneOntologyBiologicalProcessregulation of membrane potential

CACNA1A SCN11A SLC8A1 MTOR SCN2A SCN4A SCN5A SCN9A ATP1A4 SLC39A8

1.77e-045599110GO:0042391
GeneOntologyBiologicalProcessmaintenance of animal organ identity

ADGRV1 USH2A

1.91e-045912GO:0048496
GeneOntologyBiologicalProcessbehavioral response to chemical pain

SCN11A SCN9A

1.91e-045912GO:0061366
GeneOntologyBiologicalProcessbehavioral response to formalin induced pain

SCN11A SCN9A

1.91e-045912GO:0061368
GeneOntologyBiologicalProcessiron ion transport

ABCB7 SLC46A1 SLC39A14 SLC39A8

2.20e-0467914GO:0006826
GeneOntologyBiologicalProcessmulticellular organismal response to stress

CACNA1A CACNA1B SCN11A MTOR SCN9A

2.40e-04126915GO:0033555
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR3A2 TAS2R42 TAS2R4 SCN11A OR10J3 SCN9A ADGRV1 OR8D4 TAS2R50 OR2T11

2.45e-045829110GO:0050906
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN11A SCN2A SCN4A SCN5A SCN9A

2.49e-04127915GO:0070252
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

CACNA1A SLC8A1 ABCB7 ATP2C2 SLC46A1 EXT2 SLC39A14 ATP1A4 FASLG ATP13A2 SLC39A8

2.71e-047059111GO:0055080
GeneOntologyBiologicalProcesszinc ion transmembrane transport

SLC39A14 SLC30A4 SLC39A8

2.79e-0429913GO:0071577
GeneOntologyBiologicalProcesscadmium ion transport

SLC39A14 SLC39A8

2.85e-046912GO:0015691
GeneOntologyBiologicalProcessL-ornithine transmembrane transport

SLC7A3 SLC25A29

2.85e-046912GO:1903352
GeneOntologyBiologicalProcesscadmium ion transmembrane transport

SLC39A14 SLC39A8

2.85e-046912GO:0070574
GeneOntologyBiologicalProcessiron ion transmembrane transport

ABCB7 SLC39A14 SLC39A8

3.09e-0430913GO:0034755
GeneOntologyBiologicalProcesszinc ion transport

SLC39A14 SLC30A4 SLC39A8

3.09e-0430913GO:0006829
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

CACNA1A SLC8A1 ABCB7 ATP2C2 SLC46A1 EXT2 SLC39A14 ATP1A4 FASLG ATP13A2 SLC39A8

3.13e-047179111GO:0050801
GeneOntologyBiologicalProcessprotein N-linked glycosylation

OST4 EXT2 SLC39A8 STT3A

3.57e-0476914GO:0006487
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

CACNA1A SLC8A1 ABCB7 ATP2C2 SLC46A1 SLC39A14 ATP1A4 FASLG ATP13A2 SLC39A8

3.60e-046119110GO:0030003
GeneOntologyBiologicalProcessmuscle contraction

SCN11A SLC8A1 MTOR SCN2A SCN4A SCN5A SCN9A BDKRB2

3.90e-04400918GO:0006936
GeneOntologyBiologicalProcessornithine transport

SLC7A3 SLC25A29

3.99e-047912GO:0015822
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

CACNA1A SLC8A1 ABCB7 ATP2C2 SLC46A1 SLC39A14 ATP1A4 FASLG ATP13A2 SLC39A8

4.14e-046229110GO:0006873
GeneOntologyBiologicalProcessSRP-dependent cotranslational protein targeting to membrane, translocation

SEC61A2 SEC61A1

5.30e-048912GO:0006616
GeneOntologyBiologicalProcesspost-translational protein targeting to membrane, translocation

SEC61A2 SEC61A1

5.30e-048912GO:0031204
GeneOntologyBiologicalProcessactin filament-based movement

SCN11A SCN2A SCN4A SCN5A SCN9A

5.86e-04153915GO:0030048
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC26A7 MTOR LRRC8A SLC39A14 FXYD3

5.86e-04153915GO:0098656
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC7A3 SLC22A5 ATP1A4 SLC16A12

5.97e-0487914GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC7A3 SLC22A5 ATP1A4 SLC16A12

6.23e-0488914GO:0010232
GeneOntologyBiologicalProcessbicarbonate transport

SLC26A7 SLC39A14 SLC39A8

6.27e-0438913GO:0015701
GeneOntologyBiologicalProcessheme transport

ABCB7 SLC46A1

6.79e-049912GO:0015886
GeneOntologyBiologicalProcesscarnitine transport

SLC22A5 SLC25A29

6.79e-049912GO:0015879
GeneOntologyBiologicalProcessL-lysine transmembrane transport

SLC7A3 SLC25A29

8.47e-0410912GO:1903401
GeneOntologyBiologicalProcessL-lysine transport

SLC7A3 SLC25A29

8.47e-0410912GO:1902022
GeneOntologyBiologicalProcessintrinsic apoptotic signaling pathway in response to osmotic stress

SCN2A BDKRB2

8.47e-0410912GO:0008627
GeneOntologyBiologicalProcesscalcium ion import

CACNA1A CACNA1B SLC8A1 ATP2C2

9.33e-0498914GO:0070509
GeneOntologyBiologicalProcessintracellular zinc ion homeostasis

SLC39A14 ATP13A2 SLC39A8

9.65e-0444913GO:0006882
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of bitter taste

TAS2R42 TAS2R4 TAS2R50

9.65e-0444913GO:0001580
GeneOntologyBiologicalProcessglycoprotein biosynthetic process

OST4 GAL3ST4 EXT2 ABCA7 SLC39A8 DSE STT3A

1.02e-03357917GO:0009101
GeneOntologyBiologicalProcessnegative regulation of protein localization to nucleus

MAGED1 MTOR EI24

1.03e-0345913GO:1900181
GeneOntologyBiologicalProcessiodide transport

SLC26A7 MTOR

1.03e-0311912GO:0015705
GeneOntologyBiologicalProcessurate transport

SLC23A1 SLC22A12

1.03e-0311912GO:0015747
GeneOntologyBiologicalProcesszinc ion import across plasma membrane

SLC39A14 SLC39A8

1.03e-0311912GO:0071578
GeneOntologyBiologicalProcessiron coordination entity transport

ABCB7 SLC46A1

1.23e-0312912GO:1901678
GeneOntologyBiologicalProcessiron import into cell

SLC39A14 SLC39A8

1.23e-0312912GO:0033212
GeneOntologyBiologicalProcesscellular homeostasis

CACNA1A SLC8A1 ABCB7 ATP2C2 LRRC8A SLC46A1 SLC39A14 ATP1A4 FASLG ATP13A2 SLC39A8 SLC22A12

1.24e-039819112GO:0019725
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1A CACNA1B SLC8A1

1.24e-0348913GO:0098703
GeneOntologyBiologicalProcesssensory perception of bitter taste

TAS2R42 TAS2R4 TAS2R50

1.24e-0348913GO:0050913
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1A CACNA1B SLC8A1

1.24e-0348913GO:1902656
GeneOntologyBiologicalProcessdetection of stimulus

OR3A2 TAS2R42 TAS2R4 SCN11A OR10J3 SCN9A ADGRV1 OR8D4 TAS2R50 OR2T11

1.30e-037229110GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of taste

TAS2R42 TAS2R4 TAS2R50

1.40e-0350913GO:0050912
GeneOntologyBiologicalProcessintracellular chemical homeostasis

CACNA1A SLC8A1 ABCB7 ATP2C2 LRRC8A SLC46A1 SLC39A14 ATP1A4 FASLG ATP13A2 SLC39A8

1.48e-038669111GO:0055082
GeneOntologyBiologicalProcesssodium ion homeostasis

SLC8A1 EXT2 ATP1A4

1.48e-0351913GO:0055078
GeneOntologyBiologicalProcessprotein targeting to ER

SEC61A2 SPCS1 SEC61A1

1.57e-0352913GO:0045047
GeneOntologyCellularComponentbasal plasma membrane

CA9 AQP10 SLC8A1 SLC22A25 SLC26A7 SLC22A5 ATP2C2 SLC46A1 SLC39A14 SLC23A2 SLC23A1 SLC16A12 SLC39A8 CLDN1

4.06e-103549114GO:0009925
GeneOntologyCellularComponentbasal part of cell

CA9 AQP10 SLC8A1 SLC22A25 SLC26A7 SLC22A5 ATP2C2 SLC46A1 SLC39A14 SLC23A2 SLC23A1 SLC16A12 SLC39A8 CLDN1

9.52e-103789114GO:0045178
GeneOntologyCellularComponentbasolateral plasma membrane

CA9 AQP10 SLC8A1 SLC22A25 SLC26A7 SLC22A5 ATP2C2 SLC46A1 SLC39A14 SLC23A2 SLC16A12 SLC39A8 CLDN1

1.31e-093209113GO:0016323
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN2A SCN4A SCN5A SCN9A

8.31e-0917915GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN2A SCN4A SCN5A SCN9A

1.53e-0729915GO:0034706
GeneOntologyCellularComponentapical plasma membrane

SLC22A18 AQP10 SLC26A7 SLC22A5 SLC46A1 SLC39A14 USH2A SLC23A2 ABCA7 SLC23A1 SLC39A8 CLDN1 SLC22A12

1.86e-074879113GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC22A18 AQP10 SLC26A7 SLC22A5 SLC46A1 SLC39A14 USH2A SLC23A2 ABCA7 SLC23A1 SLC39A8 CLDN1 SLC22A12

1.68e-065929113GO:0045177
GeneOntologyCellularComponentendoplasmic reticulum protein-containing complex

SEC61A2 SPCS1 OST4 EXT2 SEC61A1 STT3A

1.78e-05125916GO:0140534
GeneOntologyCellularComponentcluster of actin-based cell projections

MYO15B SLC22A5 SLC46A1 ADGRV1 USH2A SLC23A1 SLC22A12

5.42e-05223917GO:0098862
GeneOntologyCellularComponentcation channel complex

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A

7.53e-05235917GO:0034703
GeneOntologyCellularComponentUSH2 complex

ADGRV1 USH2A

1.12e-044912GO:1990696
GeneOntologyCellularComponentSec61 translocon complex

SEC61A2 SEC61A1

1.86e-045912GO:0005784
GeneOntologyCellularComponentmembrane protein complex

CACNA1A CACNA1B SEC61A2 SCN11A STMP1 SPCS1 OST4 SCN2A SCN4A SCN5A SCN9A LRRC8A EXT2 ATP1A4 SEC61A1 TRAV34 STT3A

2.26e-0414989117GO:0098796
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A LRRC8A

2.44e-04378918GO:0034702
GeneOntologyCellularComponenttranslocon complex

SEC61A2 SEC61A1

2.78e-046912GO:0071256
GeneOntologyCellularComponentstereocilia ankle link

ADGRV1 USH2A

2.78e-046912GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

ADGRV1 USH2A

2.78e-046912GO:0002142
GeneOntologyCellularComponentstereocilium membrane

ADGRV1 USH2A

2.78e-046912GO:0060171
GeneOntologyCellularComponentpericiliary membrane compartment

ADGRV1 USH2A

2.78e-046912GO:1990075
GeneOntologyCellularComponentendoplasmic reticulum membrane

SEC61A2 YIPF5 ABCB9 SERINC1 MTOR SPCS1 OST4 EI24 PLA2G2A EXT2 HSD17B3 FXYD3 SEC61A1 DSE STT3A

4.41e-0412939115GO:0005789
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A LRRC8A ATP1A4

4.56e-04523919GO:1902495
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

SEC61A2 YIPF5 ABCB9 SERINC1 MTOR SPCS1 OST4 EI24 PLA2G2A EXT2 HSD17B3 FXYD3 SEC61A1 DSE STT3A

4.63e-0412999115GO:0098827
GeneOntologyCellularComponentstereocilia coupling link

ADGRV1 USH2A

5.16e-048912GO:0002139
GeneOntologyCellularComponentbrush border

MYO15B SLC22A5 SLC46A1 SLC23A1 SLC22A12

5.35e-04152915GO:0005903
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

SEC61A2 YIPF5 ABCB9 SERINC1 MTOR SPCS1 OST4 EI24 PLA2G2A EXT2 HSD17B3 FXYD3 SEC61A1 DSE STT3A

5.79e-0413279115GO:0042175
GeneOntologyCellularComponentcell projection membrane

CA9 TAS2R4 SLC22A5 SLC46A1 ADGRV1 USH2A ABCA7 SLC22A12

5.84e-04431918GO:0031253
GeneOntologyCellularComponenttransporter complex

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A LRRC8A ATP1A4

6.54e-04550919GO:1990351
GeneOntologyCellularComponentlysosomal membrane

ABCB9 MTOR LRRC8A SLC39A14 SLC30A4 ATP13A2 MFSD1 SLC39A8

9.17e-04462918GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

ABCB9 MTOR LRRC8A SLC39A14 SLC30A4 ATP13A2 MFSD1 SLC39A8

9.17e-04462918GO:0098852
GeneOntologyCellularComponentoligosaccharyltransferase complex

OST4 STT3A

1.65e-0314912GO:0008250
GeneOntologyCellularComponentvacuolar membrane

ABCB9 MTOR LRRC8A SLC39A14 SLC30A4 ATP13A2 MFSD1 SLC39A8

1.66e-03507918GO:0005774
GeneOntologyCellularComponentintercalated disc

SLC8A1 SCN2A SCN5A

3.26e-0368913GO:0014704
GeneOntologyCellularComponentT-tubule

SLC8A1 SCN2A SCN5A

4.97e-0379913GO:0030315
GeneOntologyCellularComponentbrush border membrane

SLC22A5 SLC46A1 SLC22A12

5.70e-0383913GO:0031526
GeneOntologyCellularComponentrough endoplasmic reticulum membrane

SEC61A2 SEC61A1

7.05e-0329912GO:0030867
GeneOntologyCellularComponentlateral plasma membrane

SLC26A7 SCN5A CLDN1

7.14e-0390913GO:0016328
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A ATP1A4 TRAV34

7.15e-03785919GO:0098797
HumanPhenoTalipes valgus

SCN2A SCN9A EXT2 ADGRV1

9.14e-0621344HP:0004684
HumanPhenoProgressive gait ataxia

CACNA1A SCN2A SCN9A ATP13A2

4.01e-0530344HP:0007240
HumanPhenoProgressive ataxia

CACNA1A SCN2A SCN9A ATP13A2

4.01e-0530344HP:0001329
HumanPhenoCalcaneovalgus deformity

SCN2A SCN9A EXT2 ADGRV1

6.66e-0534344HP:0001848
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN2A SCN9A ADGRV1

7.43e-0513343HP:0007058
HumanPhenoDeformed tarsal bones

SCN2A SCN9A EXT2 ADGRV1

7.48e-0535344HP:0008119
HumanPhenoLimitation of knee mobility

SCN2A SCN9A EXT2 ADGRV1

7.48e-0535344HP:0010501
HumanPhenoFacial tics

CACNA1A SCN2A SCN9A

1.17e-0415343HP:0011468
HumanPhenoAbnormal manganese concentration

SLC39A14 SLC39A8

1.29e-043342HP:0032096
HumanPhenoComplex febrile seizure

CACNA1A SCN2A SCN9A

1.43e-0416343HP:0011172
HumanPhenoAtypical absence status epilepticus

SCN2A SCN9A ADGRV1

1.73e-0417343HP:0011151
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN2A SCN9A ADGRV1

2.07e-0418343HP:0032860
HumanPhenoAtypical absence seizure

CACNA1A SCN2A SCN9A ADGRV1

2.21e-0446344HP:0007270
HumanPhenoTonic seizure

CACNA1A CACNA1B MTOR SCN2A SCN9A ADGRV1

2.76e-04140346HP:0032792
HumanPhenoNon-convulsive status epilepticus without coma

SCN2A SCN9A ADGRV1

2.87e-0420343HP:0032671
HumanPhenoDysesthesia

SCN11A SCN9A DSE

3.33e-0421343HP:0012534
HumanPhenoAtonic seizure

CACNA1A MTOR SCN2A SCN9A ADGRV1

3.50e-0494345HP:0010819
MousePhenoabnormal zinc level

SLC39A14 SLC30A4 SLC39A8

1.02e-0510633MP:0020893
MousePhenoabnormal channel response

CACNA1A CACNA1B SCN11A SCN2A

1.39e-0533634MP:0003484
MousePhenoabnormal zinc homeostasis

SLC39A14 SLC30A4 SLC39A8

2.42e-0513633MP:0009615
MousePhenoabnormal thermal nociception

CACNA1A CACNA1B PROKR1 SCN11A GPR82 SCN9A

1.06e-04168636MP:0002733
DomainNa_channel_asu

SCN11A SCN2A SCN4A SCN5A SCN9A

5.74e-1010905IPR001696
DomainNa_trans_assoc

SCN11A SCN2A SCN4A SCN5A SCN9A

5.74e-1010905IPR010526
DomainNa_trans_assoc

SCN11A SCN2A SCN4A SCN5A SCN9A

5.74e-1010905PF06512
DomainChannel_four-helix_dom

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A

1.03e-0857907IPR027359
Domain-

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A

1.03e-08579071.20.120.350
DomainMFS

SLC22A18 SLC22A25 SLC22A5 SLC46A1 MFSD1 SLC16A12 SLC22A12

8.95e-07108907PS50850
DomainIon_trans_dom

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A

1.29e-06114907IPR005821
DomainIon_trans

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A

1.29e-06114907PF00520
DomainMFS_1

SLC22A18 SLC22A25 SLC46A1 MFSD1 SLC16A12 SLC22A12

1.91e-0677906PF07690
DomainMFS

SLC22A18 SLC22A25 SLC46A1 MFSD1 SLC16A12 SLC22A12

1.91e-0677906IPR011701
DomainNa_trans_cytopl

SCN2A SCN5A SCN9A

2.14e-066903PF11933
DomainNa_trans_cytopl

SCN2A SCN5A SCN9A

2.14e-066903IPR024583
DomainTAAR_fam

TAAR2 TAAR9 TAAR6

3.73e-067903IPR009132
DomainMFS_dom

SLC22A18 SLC22A25 SLC22A5 SLC46A1 MFSD1 SLC16A12 SLC22A12

3.81e-06134907IPR020846
DomainG_PROTEIN_RECEP_F1_2

VN1R3 OR3A2 PROKR1 TAS2R42 ADRA1D OR10J3 GPR82 TAAR2 HRH4 TAAR9 OR8D4 OR2T11 BDKRB2 TAAR6

5.29e-066919014PS50262
DomainGPCR_Rhodpsn

VN1R3 OR3A2 PROKR1 TAS2R42 ADRA1D OR10J3 GPR82 TAAR2 HRH4 TAAR9 OR8D4 OR2T11 BDKRB2 TAAR6

5.38e-066929014IPR000276
DomainGPCR_Rhodpsn_7TM

OR3A2 PROKR1 TAS2R42 ADRA1D OR10J3 GPR82 TAAR2 HRH4 TAAR9 OR8D4 OR2T11 BDKRB2 TAAR6

1.88e-056709013IPR017452
DomainPlug_translocon

SEC61A2 SEC61A1

2.30e-052902PF10559
DomainSecY_su_dom

SEC61A2 SEC61A1

2.30e-052902IPR023201
DomainSecY

SEC61A2 SEC61A1

2.30e-052902PF00344
DomainSECY_1

SEC61A2 SEC61A1

2.30e-052902PS00755
DomainSECY_2

SEC61A2 SEC61A1

2.30e-052902PS00756
Domain-

SEC61A2 SEC61A1

2.30e-0529021.10.3370.10
DomainTranslocon_Sec61/SecY_plug_dom

SEC61A2 SEC61A1

2.30e-052902IPR019561
DomainSecY_CS

SEC61A2 SEC61A1

2.30e-052902IPR030659
DomainSecY/SEC61-alpha

SEC61A2 SEC61A1

2.30e-052902IPR002208
DomainG_PROTEIN_RECEP_F1_1

VN1R3 OR3A2 PROKR1 ADRA1D OR10J3 GPR82 TAAR2 HRH4 TAAR9 OR8D4 OR2T11 BDKRB2 TAAR6

2.37e-056859013PS00237
DomainXan_ur_permease

SLC23A2 SLC23A1

6.87e-053902PF00860
DomainXant/urac/vitC

SLC23A2 SLC23A1

6.87e-053902IPR006043
DomainIQ_motif_EF-hand-BS

MYO15B SCN2A SCN4A SCN5A SCN9A

7.39e-0590905IPR000048
DomainCation_ATPase_N

ATP2C2 ATP1A4 ATP13A2

8.38e-0518903SM00831
DomainIQ

MYO15B SCN2A SCN4A SCN5A SCN9A

8.64e-0593905PS50096
Domain7tm_1

OR3A2 PROKR1 ADRA1D OR10J3 GPR82 TAAR2 HRH4 TAAR9 OR8D4 OR2T11 BDKRB2 TAAR6

9.62e-056779012PF00001
DomainATPase_P-typ_cation-transptr_N

ATP2C2 ATP1A4 ATP13A2

9.92e-0519903IPR004014
DomainTDE1/TMS

SERINC1 SERINC3

2.27e-045902IPR005016
DomainSerinc

SERINC1 SERINC3

2.27e-045902PF03348
DomainTAS2R

TAS2R42 TAS2R4 TAS2R50

2.60e-0426903PF05296
DomainT2R

TAS2R42 TAS2R4 TAS2R50

2.60e-0426903IPR007960
DomainVDCC_a1su_IQ

CACNA1A CACNA1B

4.75e-047902IPR014873
DomainGPHH

CACNA1A CACNA1B

4.75e-047902PF16905
DomainGPHH_dom

CACNA1A CACNA1B

4.75e-047902IPR031649
DomainCa_chan_IQ

CACNA1A CACNA1B

4.75e-047902SM01062
DomainCa_chan_IQ

CACNA1A CACNA1B

4.75e-047902PF08763
DomainCalx_beta

SLC8A1 ADGRV1

6.31e-048902SM00237
DomainIQ

SCN2A SCN4A SCN5A SCN9A

6.32e-0481904SM00015
DomainATPase_P-typ_cyto_domN

ATP2C2 ATP1A4 ATP13A2

6.33e-0435903IPR023299
DomainP_typ_ATPase

ATP2C2 ATP1A4 ATP13A2

6.89e-0436903IPR001757
DomainATPase_P-typ_P_site

ATP2C2 ATP1A4 ATP13A2

6.89e-0436903IPR018303
DomainATPASE_E1_E2

ATP2C2 ATP1A4 ATP13A2

6.89e-0436903PS00154
DomainATPase_P-typ_transduc_dom_A

ATP2C2 ATP1A4 ATP13A2

7.47e-0437903IPR008250
DomainE1-E2_ATPase

ATP2C2 ATP1A4 ATP13A2

7.47e-0437903PF00122
DomainCalx_beta

SLC8A1 ADGRV1

8.09e-049902IPR003644
DomainCalx-beta

SLC8A1 ADGRV1

8.09e-049902PF03160
DomainVDCCAlpha1

CACNA1A CACNA1B

1.01e-0310902IPR002077
DomainABC_transporter_CS

ABCB7 ABCB9 ABCA7

1.08e-0342903IPR017871
DomainABC_tran

ABCB7 ABCB9 ABCA7

1.60e-0348903PF00005
DomainABC_TRANSPORTER_2

ABCB7 ABCB9 ABCA7

1.60e-0348903PS50893
DomainABC_TRANSPORTER_1

ABCB7 ABCB9 ABCA7

1.70e-0349903PS00211
DomainABC_transporter-like

ABCB7 ABCB9 ABCA7

1.80e-0350903IPR003439
DomainZip

SLC39A14 SLC39A8

2.01e-0314902PF02535
DomainZIP

SLC39A14 SLC39A8

2.01e-0314902IPR003689
Domain7TM_GPCR_Srsx

ADRA1D TAAR2 TAAR9 TAAR6

2.11e-03112904SM01381
Domain-

ATP2C2 ATP1A4

2.64e-03169021.20.1110.10
DomainATPase_P-typ_TM_dom

ATP2C2 ATP1A4

2.64e-0316902IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP2C2 ATP1A4

2.98e-0317902IPR006068
DomainCation_ATPase_C

ATP2C2 ATP1A4

2.98e-0317902PF00689
DomainCation_ATPase_N

ATP2C2 ATP1A4

3.34e-0318902PF00690
DomainTetraspanin_CS

TSPAN17 CD37

4.54e-0321902IPR018503
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC22A18 AQP10 SLC8A1 ABCB7 SLC7A3 ABCB9 SLC26A7 SLC22A5 ATP2C2 LRRC8A SLC5A9 SLC46A1 SLC25A29 SLC39A14 ATP1A4 FXYD3 ATP13A2 ABCA7 SLC39A8 SLC22A12

4.19e-107367220M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC22A18 SLC8A1 ABCB7 SLC7A3 ABCB9 SLC26A7 SLC22A5 ATP2C2 LRRC8A SLC5A9 SLC46A1 SLC25A29 SLC39A14 ATP1A4 FXYD3 ATP13A2 ABCA7 SLC39A8 SLC22A12

8.17e-106817219MM14985
PathwayREACTOME_CARDIAC_CONDUCTION

SCN11A SLC8A1 SCN2A SCN4A SCN5A SCN9A ATP1A4 FXYD3

3.07e-07130728M27454
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC22A18 SLC8A1 SLC7A3 SLC26A7 SLC22A5 SLC5A9 SLC25A29 SLC39A14 SLC39A8 SLC22A12

3.34e-072387210MM15076
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SCN2A SCN4A SCN5A SCN9A

4.63e-0731725M877
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC22A18 SLC8A1 SLC7A3 SLC26A7 SLC22A5 SLC5A9 SLC25A29 SLC39A14 SLC39A8 SLC22A12

5.06e-072497210M5988
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN11A SCN2A SCN4A SCN5A SCN9A

5.46e-0732725M27455
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

ADRA1D TAAR2 HRH4 TAAR9 TAAR6

2.22e-0642725M5868
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

ADRA1D TAAR2 HRH4 TAAR9 TAAR6

2.22e-0642725MM14971
PathwayKEGG_TASTE_TRANSDUCTION

CACNA1A CACNA1B TAS2R42 TAS2R4 TAS2R50

6.51e-0652725M5785
PathwayREACTOME_MUSCLE_CONTRACTION

SCN11A SLC8A1 SCN2A SCN4A SCN5A SCN9A ATP1A4 FXYD3

8.75e-06203728M5485
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A18 SLC22A5 SLC22A12

2.72e-0512723MM15192
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A18 SLC22A5 SLC39A14 SLC39A8 SLC22A12

4.21e-0576725MM15072
PathwayREACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT

SLC22A18 SLC22A5 SLC22A12

5.56e-0515723M888
PathwayREACTOME_GPCR_LIGAND_BINDING

PROKR1 TAS2R42 TAS2R4 ADRA1D TAAR2 HRH4 TAAR9 TAS2R50 BDKRB2 TAAR6

6.21e-054307210MM15160
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A18 SLC22A5 SLC39A14 SLC39A8 SLC22A12

6.81e-0584725M27334
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

TAS2R4 SCN2A SCN9A TAS2R50

9.45e-0547724M42524
PathwayREACTOME_GPCR_LIGAND_BINDING

PROKR1 TAS2R42 TAS2R4 ADRA1D TAAR2 HRH4 TAAR9 TAS2R50 BDKRB2 TAAR6

1.15e-044637210M507
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP2C2 ATP1A4 FXYD3 ATP13A2

1.75e-0455724M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP2C2 ATP1A4 FXYD3 ATP13A2

2.01e-0457724MM15643
PathwayKEGG_PROTEIN_EXPORT

SEC61A2 SPCS1 SEC61A1

2.39e-0424723M6981
PathwayREACTOME_L1CAM_INTERACTIONS

SCN11A SCN2A SCN4A SCN5A SCN9A

3.79e-04121725M872
PathwayKEGG_MEDICUS_REFERENCE_FE_TF_TRANSPORT

SLC39A14 SLC39A8

5.31e-047722M47925
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN11A ADRA1D MTOR SCN2A SCN4A SCN5A SCN9A SLC46A1

5.47e-04367728M48346
PathwayREACTOME_ZINC_INFLUX_INTO_CELLS_BY_THE_SLC39_GENE_FAMILY

SLC39A14 SLC39A8

7.06e-048722MM15106
PathwayREACTOME_ORGANIC_CATION_TRANSPORT

SLC22A18 SLC22A5

7.06e-048722MM15191
PathwayREACTOME_VITAMIN_C_ASCORBATE_METABOLISM

SLC23A2 SLC23A1

7.06e-048722M27091
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

TAS2R42 TAS2R4 TAS2R50

8.76e-0437723MM15067
PathwayWP_ZINC_HOMEOSTASIS

SLC39A14 SLC30A4 SLC39A8

8.76e-0437723M39377
PathwayREACTOME_SERINE_BIOSYNTHESIS

SERINC1 SERINC3

9.05e-049722M27959
PathwayREACTOME_SERINE_BIOSYNTHESIS

SERINC1 SERINC3

9.05e-049722MM15707
PathwayREACTOME_VITAMIN_C_ASCORBATE_METABOLISM

SLC23A2 SLC23A1

9.05e-049722MM14769
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1A CACNA1B SLC8A1 ADRA1D ATP1A4

9.19e-04147725MM15854
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

TAS2R42 TAS2R4 TAS2R50

1.02e-0339723M793
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1A CACNA1B SLC8A1 ADRA1D ATP1A4

1.04e-03151725M39329
PathwayREACTOME_ZINC_INFLUX_INTO_CELLS_BY_THE_SLC39_GENE_FAMILY

SLC39A14 SLC39A8

1.13e-0310722M27361
PathwayREACTOME_ORGANIC_CATION_TRANSPORT

SLC22A18 SLC22A5

1.13e-0310722M27450
PathwayWP_GPCRS_ODORANT

GPR82 TAAR2 TAAR9 TAS2R50 TAAR6

1.23e-03157725MM15872
PathwayWP_GPCRS_OTHER

ADRA1D TAAR2 HRH4 ADGRV1

1.30e-0393724M39629
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B

1.37e-0311722MM14498
PathwayREACTOME_ZINC_TRANSPORTERS

SLC39A14 SLC39A8

1.37e-0311722MM15101
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B

1.37e-0311722M26913
PathwayBIOCARTA_VITCB_PATHWAY

SLC23A2 SLC23A1

1.37e-0311722M15422
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1B

1.37e-0311722M47958
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

PROKR1 ADRA1D TAAR2 HRH4 TAAR9 BDKRB2 TAAR6

1.45e-03330727M18334
PathwayKEGG_ABC_TRANSPORTERS

ABCB7 ABCB9 ABCA7

1.46e-0344723M11911
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

PROKR1 ADRA1D TAAR2 HRH4 TAAR9 BDKRB2 TAAR6

1.52e-03333727MM14963
PathwayREACTOME_SIGNALING_BY_GPCR

PROKR1 TAS2R42 TAS2R4 ADRA1D TAAR2 HRH4 TAAR9 TAS2R50 BDKRB2 TAAR6

1.57e-036467210MM14962
PathwayBIOCARTA_VITCB_PATHWAY

SLC23A2 SLC23A1

1.64e-0312722MM1526
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

CACNA1A CACNA1B MTOR

1.76e-0347723M19708
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1B SLC8A1 ADRA1D BDKRB2

2.14e-03178725M2890
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC8A1 SLC7A3 SLC26A7 SLC25A29

2.25e-03108724M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC8A1 SLC7A3 SLC26A7 SLC25A29

2.32e-03109724MM15074
PathwayREACTOME_ZINC_TRANSPORTERS

SLC39A14 SLC39A8

2.59e-0315722M832
PathwayREACTOME_ION_HOMEOSTASIS

SLC8A1 ATP1A4 FXYD3

2.63e-0354723M27460
PathwayREACTOME_ION_HOMEOSTASIS

SLC8A1 ATP1A4 FXYD3

2.63e-0354723MM15202
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

ADRA1D TAAR2 HRH4 TAAR9 BDKRB2 TAAR6

2.63e-03272726M13380
PathwayREACTOME_SIGNALING_BY_GPCR

PROKR1 TAS2R42 TAS2R4 ADRA1D TAAR2 HRH4 TAAR9 TAS2R50 BDKRB2 TAAR6

2.88e-037027210M746
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN11A SCN2A SCN4A SCN5A SCN9A

1.45e-11992516382098
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN5A SCN9A

1.79e-08392320038812
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1A CACNA1B SCN11A SLC8A1 SCN4A SCN5A SCN9A

9.23e-0813992716985003
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN11A SCN5A SCN9A

1.78e-07592322875929
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN4A SCN5A

1.78e-07592317724025
Pubmed

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.

SEC61A2 SPCS1 SEC61A1

3.56e-07692316705175
Pubmed

Differential expression of intestinal membrane transporters in cholera patients.

AQP10 SLC30A4 SLC23A1

6.22e-07792317575980
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

SLC22A18 ABCB7 SERINC1 TMEM245 SCN9A EI24 LRRC8A SEC61A1 BDKRB2 STT3A

8.52e-07499921022810586
Pubmed

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.

TAAR2 TAAR9 TAAR6

1.49e-06992315718104
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN2A SCN4A SCN5A

1.49e-06992315746173
Pubmed

A second class of chemosensory receptors in the olfactory epithelium.

TAAR2 TAAR9 TAAR6

1.49e-06992316878137
Pubmed

Expression of trace amine-associated receptors in the Grueneberg ganglion.

TAAR2 TAAR9 TAAR6

2.12e-061092317556730
Pubmed

A high-density association screen of 155 ion transport genes for involvement with common migraine.

ATP2C2 SCN5A SCN9A

3.87e-061292318676988
Pubmed

Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.

SLC22A25 SLC22A5 SLC22A12

5.03e-061392315369770
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN2A SCN5A SCN9A

5.03e-061392315123669
Pubmed

ZIP14 and ZIP8 zinc/bicarbonate symporters in Xenopus oocytes: characterization of metal uptake and inhibition.

SLC39A14 SLC39A8

6.92e-06292223090441
Pubmed

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.

SCN4A SCN9A

6.92e-06292218079277
Pubmed

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.

CACNA1A CACNA1B

6.92e-06292223426690
Pubmed

A human nucleobase transporter-like cDNA (SLC23A1): member of a transporter family conserved from bacteria to mammals.

SLC23A2 SLC23A1

6.92e-06292210395795
Pubmed

N-Glycosylation is required for Na+-dependent vitamin C transporter functionality.

SLC23A2 SLC23A1

6.92e-06292218619416
Pubmed

Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma.

SLC23A2 SLC23A1

6.92e-06292218791929
Pubmed

Temporo-spacial microanatomical distribution of the murine sodium-dependent ascorbic acid transporters Slc23a1 and Slc23a2 in the kidney throughout development.

SLC23A2 SLC23A1

6.92e-06292228177761
Pubmed

Genetic variation in the sodium-dependent vitamin C transporters, SLC23A1, and SLC23A2 and risk for preterm delivery.

SLC23A2 SLC23A1

6.92e-06292216357110
Pubmed

Functional role of conserved transmembrane segment 1 residues in human sodium-dependent vitamin C transporters.

SLC23A2 SLC23A1

6.92e-06292218247577
Pubmed

Human vitamin C (L-ascorbic acid) transporter SVCT1.

SLC23A2 SLC23A1

6.92e-06292210631088
Pubmed

A family of mammalian Na+-dependent L-ascorbic acid transporters.

SLC23A2 SLC23A1

6.92e-06292210331392
Pubmed

Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.

CACNA1A CACNA1B

6.92e-06292223376566
Pubmed

Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors.

CA9 MTOR

6.92e-06292227153561
Pubmed

Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14.

SLC39A14 SLC39A8

6.92e-06292231261654
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

6.92e-06292211834499
Pubmed

Limited Association Between Ascorbate Concentrations and Vitamin C Transporters in Renal Cell Carcinoma Cells and Clinical Samples.

SLC23A2 SLC23A1

6.92e-06292234599650
Pubmed

Hepatic expression of sodium-dependent vitamin C transporters: ontogeny, subtissular distribution and effect of chronic liver diseases.

SLC23A2 SLC23A1

6.92e-06292221733302
Pubmed

CaV 2.1 α1  subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.

CACNA1A CACNA1B

6.92e-06292238155373
Pubmed

Senescence-induced increases in intracellular oxidative stress and enhancement of the need for ascorbic acid in human fibroblasts.

SLC23A2 SLC23A1

6.92e-06292223613229
Pubmed

Vitamin C transporter gene polymorphisms, dietary vitamin C and serum ascorbic acid.

SLC23A2 SLC23A1

6.92e-06292220588054
Pubmed

Activity of a sodium-dependent vitamin C transporter (SVCT) in MDCK-MDR1 cells and mechanism of ascorbate uptake.

SLC23A2 SLC23A1

6.92e-06292218417304
Pubmed

Promoter analysis of the human ascorbic acid transporters SVCT1 and 2: mechanisms of adaptive regulation in liver epithelial cells.

SLC23A2 SLC23A1

6.92e-06292220471816
Pubmed

Gender and sodium-ascorbate transporter isoforms determine ascorbate concentrations in mice.

SLC23A2 SLC23A1

6.92e-06292215333707
Pubmed

Effects of functional variants of vitamin C transporter genes on apolipoprotein E E4-associated risk of cognitive decline: The Nakajima study.

SLC23A2 SLC23A1

6.92e-06292234780525
Pubmed

Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.

SCN2A SCN5A

6.92e-06292216847056
Pubmed

Specialized functions of Nav1.5 and Nav1.9 channels in electrogenesis of myenteric neurons in intact mouse ganglia.

SCN11A SCN5A

6.92e-06292224719102
Pubmed

Impact of SLC23A1 and SLC23A2 Polymorphisms on the Risk for Preeclampsia in a Chinese Han Population.

SLC23A2 SLC23A1

6.92e-06292236310070
Pubmed

Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.

ADGRV1 USH2A

6.92e-06292215671307
Pubmed

Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.

ADGRV1 USH2A

6.92e-06292234638692
Pubmed

Hierarchal contribution of N- and C-terminal sequences to the differential localization of homologous sodium-dependent vitamin C transporters, SVCT1 and SVCT2, in epithelial cells.

SLC23A2 SLC23A1

6.92e-06292219216494
Pubmed

Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.

SEC61A2 SEC61A1

6.92e-06292218480044
Pubmed

Essential role of intracellular glutathione in controlling ascorbic acid transporter expression and function in rat hepatocytes and hepatoma cells.

SLC23A2 SLC23A1

6.92e-06292222348976
Pubmed

Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2.

SLC23A2 SLC23A1

6.92e-06292210556521
Pubmed

Genetic variation in sodium-dependent ascorbic acid transporters and risk of gastric cancer in Poland.

SLC23A2 SLC23A1

6.92e-06292219243932
Pubmed

Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function.

SLC23A2 SLC23A1

6.92e-06292210471399
Pubmed

Polarized localization of vitamin C transporters, SVCT1 and SVCT2, in epithelial cells.

SLC23A2 SLC23A1

6.92e-06292215993839
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

6.92e-06292226861708
Pubmed

Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.

ADGRV1 USH2A

6.92e-06292228653555
Pubmed

Identification of a ubiquitous family of membrane proteins and their expression in mouse brain.

SERINC1 SERINC3

6.92e-06292210637174
Pubmed

Polymorphisms in sodium-dependent vitamin C transporter genes and plasma, aqueous humor and lens nucleus ascorbate concentrations in an ascorbate depleted setting.

SLC23A2 SLC23A1

6.92e-06292224815519
Pubmed

Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract.

SLC23A2 SLC23A1

6.92e-06292227932501
Pubmed

Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.

SCN4A SCN5A

6.92e-06292230944319
Pubmed

Vitamin C transport systems of mammalian cells.

SLC23A2 SLC23A1

6.92e-06292211396616
Pubmed

Cadmium concentrations in human blood and urine are associated with polymorphisms in zinc transporter genes.

SLC39A14 SLC39A8

6.92e-06292224514587
Pubmed

Slc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter.

SLC39A14 SLC39A8

6.92e-06292218270315
Pubmed

Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells.

SLC23A2 SLC23A1

6.92e-06292218845575
Pubmed

The solute carriers ZIP8 and ZIP14 regulate manganese accumulation in brain microvascular endothelial cells and control brain manganese levels.

SLC39A14 SLC39A8

6.92e-06292231699897
Pubmed

Physiologic implications of metal-ion transport by ZIP14 and ZIP8.

SLC39A14 SLC39A8

6.92e-06292222318508
Pubmed

Focal increases of axoplasmic Ca2+, aggregation of sodium-calcium exchanger, N-type Ca2+ channel, and actin define the sites of spheroids in axons undergoing oxidative stress.

CACNA1B SLC8A1

6.92e-06292222933787
Pubmed

Sodium-dependent vitamin C transporter isoforms in skin: Distribution, kinetics, and effect of UVB-induced oxidative stress.

SLC23A2 SLC23A1

6.92e-06292217664139
Pubmed

The N-terminal basolateral targeting signal unlikely acts alone in the differential trafficking of membrane transporters in MDCK cells.

SLC23A2 SLC23A1

6.92e-06292223837633
Pubmed

Painful and painless mutations of SCN9A and SCN11A voltage-gated sodium channels.

SCN11A SCN9A

6.92e-06292232601768
Pubmed

New view at C.

SLC23A2 SLC23A1

6.92e-06292211984580
Pubmed

Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival.

SLC23A2 SLC23A1

6.92e-06292211984597
Pubmed

Expression analysis of P/Q-type Ca2+ channel alpha 1A subunit mRNA in olfactory mitral cell in N-type Ca2+ channel alpha 1B subunit gene-deficient mice.

CACNA1A CACNA1B

6.92e-06292215050706
Pubmed

Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters.

SLC23A2 SLC23A1

6.92e-0629229804989
Pubmed

Tissue-Specific Induction of Mouse ZIP8 and ZIP14 Divalent Cation/Bicarbonate Symporters by, and Cytokine Response to, Inflammatory Signals.

SLC39A14 SLC39A8

6.92e-06292224728862
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC7A3 SLC22A5 ATP1A4 SLC16A12 CLDN1

9.10e-0610592530280653
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

ADRA1D TAAR2 HRH4 TAAR9 BDKRB2 TAAR6

1.59e-0520092618240029
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN9A

2.07e-05392219284629
Pubmed

Calcium and the Ca-ATPase SPCA1 modulate plasma membrane abundance of ZIP8 and ZIP14 to regulate Mn(II) uptake in brain microvascular endothelial cells.

SLC39A14 SLC39A8

2.07e-05392235787370
Pubmed

Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds.

CA9 SLC46A1

2.07e-05392232493992
Pubmed

Munc13-3 Is Required for the Developmental Localization of Ca2+ Channels to Active Zones and the Nanopositioning of Cav2.1 Near Release Sensors.

CACNA1A CACNA1B

2.07e-05392229466725
Pubmed

Metal-ion transporter SLC39A8 is required for brain manganese uptake and accumulation.

SLC39A14 SLC39A8

2.07e-05392237482277
Pubmed

Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells.

SLC39A14 SLC39A8

2.07e-05392222534978
Pubmed

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.

ADGRV1 USH2A

2.07e-05392220440071
Pubmed

Increased free Zn2+ correlates induction of sarco(endo)plasmic reticulum stress via altered expression levels of Zn2+ -transporters in heart failure.

SLC39A14 SLC39A8

2.07e-05392229333637
Pubmed

Human macrophage differentiation induces OCTN2-mediated L-carnitine transport through stimulation of mTOR-STAT3 axis.

MTOR SLC22A5

2.07e-05392227733576
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1B

2.07e-05392238996073
Pubmed

Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice.

SLC23A2 SLC23A1

2.07e-05392220122894
Pubmed

Genetic Analysis of SCN11A, SCN10A, and SCN9A in Familial Episodic Pain Syndrome (FEPS) in Japan and Proposal of Clinical Diagnostic Criteria.

SCN11A SCN9A

2.07e-05392238999942
Pubmed

Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.

CACNA1A CACNA1B

2.07e-05392229208674
Pubmed

Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation.

CACNA1A CACNA1B

2.07e-05392226507659
Pubmed

The Functions of ZIP8, ZIP14, and ZnT10 in the Regulation of Systemic Manganese Homeostasis.

SLC39A14 SLC39A8

2.07e-05392232392784
Pubmed

Non-USH2A mutations in USH2 patients.

ADGRV1 USH2A

2.07e-05392222147658
Pubmed

Calmodulin mediates Ca2+ sensitivity of sodium channels.

SCN2A SCN5A

2.07e-05392215316014
Pubmed

Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting.

CACNA1A CACNA1B

2.07e-05392224394417
Pubmed

Manganese transport in mammals by zinc transporter family proteins, ZNT and ZIP.

SLC39A14 SLC39A8

2.07e-05392234924116
Pubmed

Targeted next generation sequencing in Italian patients with Usher syndrome: phenotype-genotype correlations.

ADGRV1 USH2A

2.07e-05392229142287
Pubmed

Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin.

SCN4A SCN5A

2.07e-05392215746172
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1B

2.07e-05392224523520
Pubmed

Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.

SCN11A SCN9A

2.07e-05392230554136
Pubmed

The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.

ADGRV1 USH2A

2.07e-05392216434480
Pubmed

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.

SCN11A SCN9A

2.07e-05392215302875
Pubmed

A novel family of mammalian taste receptors.

TAS2R42 TAS2R4 TAS2R50

2.30e-052192310761934
InteractionNALCN interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

2.59e-0914875int:NALCN
InteractionSCN11A interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

3.87e-0915875int:SCN11A
InteractionSCN9A interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

2.57e-0821875int:SCN9A
InteractionCACNA1D interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

5.32e-0824875int:CACNA1D
InteractionSCN1A interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

1.46e-0729875int:SCN1A
InteractionCACNA1B interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

5.22e-0737875int:CACNA1B
InteractionSCN5A interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

1.78e-0647875int:SCN5A
InteractionCACNA1C interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

6.57e-0661875int:CACNA1C
InteractionSCN10A interactions

CACNA1A SCN11A SCN5A

1.25e-0511873int:SCN10A
InteractionTTYH1 interactions

SLC7A3 ABCB9 SPCS1 LRRC8A ADCK2 TMEM143 ATP13A2 ABCA7

4.63e-05300878int:TTYH1
InteractionSLC39A4 interactions

SLC22A18 EI24 LRRC8A SLC46A1 TMEM143 ATP13A2

7.51e-05163876int:SLC39A4
InteractionATP2C1 interactions

SCN11A YIPF5 ATP2C2 SCN5A SCN9A

7.64e-05101875int:ATP2C1
InteractionSCN8A interactions

SCN11A SCN4A SCN5A

8.40e-0520873int:SCN8A
InteractionCACNB4 interactions

CACNA1A CACNA1B FASLG

1.67e-0425873int:CACNB4
InteractionPOMK interactions

SEC61A2 SLC22A18 SCN4A EI24 SLC39A14 SEC61A1 STT3A

1.72e-04271877int:POMK
InteractionCACNA1A interactions

CACNA1A CACNA1B SCN11A SCN5A SCN9A

1.93e-04123875int:CACNA1A
GeneFamilySolute carriers

SLC22A18 SLC8A1 SLC22A25 SLC7A3 SLC26A7 SLC22A5 SLC5A9 SLC46A1 SLC25A29 SLC39A14 SLC30A4 SLC23A2 SLC23A1 SLC16A12 SLC39A8 SLC22A12

2.13e-123957116752
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN2A SCN4A SCN5A SCN9A

1.01e-1097151203
GeneFamilyTrace amine receptors

TAAR2 TAAR9 TAAR6

4.79e-069713188
GeneFamilyFibronectin type III domain containing|USH2 complex

ADGRV1 USH2A

9.08e-0547121244
GeneFamilyTaste 2 receptors

TAS2R42 TAS2R4 TAS2R50

4.79e-04397131162
GeneFamilyATP binding cassette subfamily B

ABCB7 ABCB9

8.17e-0411712806
GeneFamilyOligosaccharyltransferase complex subunits

OST4 STT3A

9.78e-0412712445
GeneFamilyClaudins

CLDN14 CLDN1

3.65e-0323712488
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1B

4.65e-0326712253
GeneFamilyCD molecules|Tetraspanins

TSPAN17 CD37

7.42e-0333712768
GeneFamilyMAGE family

MAGEB5 MAGED1

1.08e-02407121136
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

CUL4A SEC61A2 SERINC1 TMEM245 SLC46A1 EXT2 SLC39A14 SEC61A1 SLC23A2 MFSD1 STT3A

1.95e-056818911M5314
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

CUL4A SEC61A2 SERINC1 SERINC3 SLC39A14 SEC61A1 SLC23A2 ABCA7 STT3A

2.55e-05457899M1613
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

CUL4A SEC61A2 SERINC1 TMEM245 SLC46A1 EXT2 SLC39A14 SEC61A1 SLC23A2 MFSD1 STT3A

2.61e-057038911MM1055
CoexpressionMILI_PSEUDOPODIA_CHEMOTAXIS_DN

CUL4A SEC61A2 SERINC1 SERINC3 SLC39A14 SEC61A1 SLC23A2 ABCA7 STT3A

3.17e-05470899MM1053
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 SERINC1 EXT2 DAAM1 SLC39A14 SEC61A1 STT3A

1.59e-0719691766d76249bd2770cdddff2c1fe59a016e95da2124
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 SERINC1 EXT2 DAAM1 SLC39A14 SEC61A1 STT3A

1.59e-071969179bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 SCN2A SCN9A ADGRV1 ATP1A4 USH2A

2.15e-061849162cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 SCN2A SCN9A ADGRV1 ATP1A4 USH2A

2.15e-06184916ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 SCN2A SCN9A ADGRV1 ATP1A4 USH2A

2.15e-061849162b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-SCAT-Fat-3m|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 OST4 SERINC3 TNKS2 SEC61A1 STT3A

2.44e-06188916b8dff61240e5052c2fbf7f28b86fe41822df45b0
ToppCellfacs-Trachea-3m|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAGED1 SERINC1 SERINC3 EXT2 SEC61A1 STT3A

3.19e-06197916e77016d64b1cac9825fec7cfe5071f1567401187
ToppCellfacs-Trachea-nan-3m|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 SERINC1 SERINC3 EXT2 SEC61A1 STT3A

3.19e-061979160353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC1 OST4 SERINC3 TNKS2 SEC61A1 STT3A

3.29e-061989162f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC1 OST4 SERINC3 TNKS2 SEC61A1 STT3A

3.29e-06198916f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC1 OST4 SERINC3 TNKS2 SEC61A1 STT3A

3.39e-061999168d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTOR SLC39A14 SLC23A1 SLC39A8 SLC22A12

2.06e-051629156972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCellC_02|World / shred on cell type and cluster

SLC8A1 MYO15B OVOS2 SLC5A9 SLC23A2

2.25e-05165915a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCellsevere-B_memory|severe / disease stage, cell group and cell class

SCN2A CD37 MINAR1 EBF1 DAAM1

2.82e-051739153a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

C1QA GAL3ST4 SLC46A1 ATP1A4 MFSD1

2.90e-0517491575b3a852140fb726025c3c987143d67944afde2d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD37 SCN4A EBF1 ADGRV1 USH2A

3.07e-05176915c6484334187f64cd00cd35e77d8ae436556b4260
ToppCellsevere-B_memory|World / disease stage, cell group and cell class

SCN2A CD37 MINAR1 EBF1 DAAM1

3.07e-051769154e5c6b1aa5ffd13593a6bcd1e1253c1737c5c2b4
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CA9 CACNA1A SCN11A SLC26A7 ADGRV1

3.32e-051799158ce5000088b727783a0619baa16a2cd036d21f54
ToppCellfacs-Brain_Non-Myeloid-Striatum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD37 C1QA GAL3ST4 FXYD3 CLDN1

3.69e-05183915824ecda1219fb596a01bf5cfeee29a6daa462098
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD37 C1QA GAL3ST4 FXYD3 CLDN1

3.69e-0518391582b84ee065fb573688d59da97a327152a1ba294c
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN14 MAGED1 ATP2C2 PLA2G2A FXYD3

3.69e-05183915ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN14 MAGED1 ATP2C2 PLA2G2A FXYD3

3.69e-05183915c52b84034503d931f7b87312d2ff86daff14152d
ToppCellLeuk-UTI-Other-RBC|Leuk-UTI / Disease, Lineage and Cell Type

SPCS1 SCN9A OVOS2 DAAM1 ATP13A2

3.89e-051859155b5dd856d6efc0539d92533cff134bbc3f98be45
ToppCellLeuk-UTI-Other|Leuk-UTI / Disease, Lineage and Cell Type

SPCS1 SCN9A OVOS2 DAAM1 ATP13A2

3.89e-05185915895e8087e97ac0eab3446385e6e0dd24bea7f42c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CA9 MAGED1 ATP2C2 FXYD3 BDKRB2

4.09e-0518791582bbc107f58c623f3b90430c90c562624a12abef
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SLC8A1 ADRA1D SLC26A7 PLA2G2A EBF1

4.09e-05187915406ff9327d3109fe1e251629c4c617b00a573dc2
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC8A1 SCN9A C1QA GAL3ST4 ATP1A4

4.20e-051889159fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B PROKR1 SCN11A SCN5A SCN9A

4.31e-05189915cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAGED1 ABCB9 SPCS1 SEC61A1 STT3A

4.53e-051919157b4b5d90d1023d03239ed986f273afa734d3124d
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB9 ATP2C2 C1QA FXYD3 SLC39A8

4.76e-051939156a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|367C / Donor, Lineage, Cell class and subclass (all cells)

SLC8A1 SCN9A C1QA GAL3ST4 MFSD1

4.87e-05194915e3688f4252aae5f849f025d7f453ff4c0c14590b
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAGED1 SPCS1 OST4 SEC61A1 STT3A

4.87e-051949153c30f86806f6a0f43e6103ad7009f4c6a90e011c
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCN9A C1QA GAL3ST4 MFSD1 DSE

4.87e-0519491548c37251518f96524807b5bd1bbc2820637666ad
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCN9A C1QA GAL3ST4 MFSD1 DSE

4.87e-051949157b6a34d1f8922b71dcc931421666c1822cec8345
ToppCellCV-Severe-6|Severe / Virus stimulation, Condition and Cluster

CA9 TSPAN17 STMP1 SERINC1 SERINC3

4.87e-05194915d33be6ed1de907aeea0c2dce09796556b8efdd4e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC8A1 GPR82 SCN9A SLC30A4 CLDN1

4.87e-05194915e56c6e5c9b7d287ae94566b561e21cec2055f83d
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCN9A C1QA GAL3ST4 MFSD1 DSE

4.87e-05194915435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC8A1 C1QA GAL3ST4 SLC46A1 MFSD1

4.99e-05195915c16479a10f5ca2e89aea1742dbc5cc4dc9f3ea88
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC8A1 GPR82 SCN9A SLC30A4 CLDN1

4.99e-0519591585fee07d71c0393ea42bcf1130566dff4a62f507
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SLC26A7 SCN2A SLC25A29 FXYD3

4.99e-051959150ac7762197cdd8d643f87148573a8df6e936c1b0
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAGED1 SPCS1 OST4 SEC61A1 STT3A

4.99e-05195915fb3d6a3b10aedc7fdd9789b2c47b4e80fa8e411f
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC1 GAL3ST4 SERINC3 MFSD1 STT3A

5.24e-05197915e73ca8c8f42cbcc56eaa5fe3d69abd1ce7b7bbca
ToppCellfacs-Brain_Myeloid-Cortex_|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC1 GAL3ST4 SERINC3 MFSD1 STT3A

5.24e-0519791581379fe6bd14a1ba26f4a159497262adcb600b18
ToppCellfacs-Brain_Myeloid-Cortex_-18m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC1 GAL3ST4 SERINC3 MFSD1 STT3A

5.24e-05197915271c75f491d03bd248c7ec037ef02e39456f3ac0
ToppCellB_cells-Plasma_cells_and_plasmablasts|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

MAGED1 SPCS1 SEC61A1 SLC39A8 STT3A

5.24e-051979153b1c574b3d119b63967bb1306f0353ecc4c522f3
ToppCellmild-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ABCB9 SLC39A14 SEC61A1 SLC23A1 STT3A

5.24e-0519791521085d5e27b5a23a241a933058bb89f8a1fcf198
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC1 GAL3ST4 SERINC3 MFSD1 STT3A

5.24e-051979159db329c6fea532dd1afb624f4c29c92407f45568
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC1 GAL3ST4 SERINC3 MFSD1 STT3A

5.24e-05197915173c0c8de4e69882a9f91189deeb4a651fefe551
ToppCelldistal-3-Hematologic-IGSF21+_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC8A1 SCN9A C1QA GAL3ST4 MFSD1

5.24e-0519791552e9dc35dd8cc2605fa4894bb16bb5c6086faa76
ToppCellB_cells-Plasmablasts|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

YIPF5 MAGED1 SPCS1 SEC61A1 STT3A

5.37e-05198915c6cab47885be74a64351f843a741dea6d911bde4
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2|World / Primary Cells by Cluster

SLC8A1 SERINC1 SCN2A SCN9A DAAM1

5.50e-05199915f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCellSepsis-Leuk-UTI-Others|Leuk-UTI / Disease, condition lineage and cell class

MAGED1 SPCS1 SCN9A DAAM1 ATP13A2

5.50e-05199915e45fe91f1d1c47a305b0f39d808730723852af00
ToppCellSepsis-Leuk-UTI-Others-RBC|Leuk-UTI / Disease, condition lineage and cell class

MAGED1 SPCS1 SCN9A DAAM1 ATP13A2

5.50e-05199915d9b517199a646c9461c615412ad5b58cf4bed7c8
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV|World / Primary Cells by Cluster

SLC8A1 SERINC1 SCN2A SCN9A DAAM1

5.50e-05199915e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCellSevere_COVID-19-Myeloid-MoAM1|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

SLC8A1 C1QA GAL3ST4 MFSD1 DSE

5.50e-051999158895332f0026e59cd19f41de0ef014f7b2af74e1
ToppCellcellseq-Immune-Immune_Myeloid-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC8A1 C1QA GAL3ST4 MFSD1 DSE

5.50e-05199915b3267d5a7ae0461f5e9e6a3ab6783317a8c42506
ToppCellcellseq-Immune-Immune_Myeloid-IM-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC8A1 C1QA GAL3ST4 MFSD1 DSE

5.50e-0519991501dacee8bb392639d475be3cb27ba3eeff1e57f1
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

CACNA1A MYO15B SERINC3 SLC46A1 SLC39A8

5.63e-05200915118321ac443feb42aee171baccfc4610f00a8822
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-mo-Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SLC8A1 C1QA GAL3ST4 MFSD1 DSE

5.63e-05200915b3f4eb45545f1632dc62f942756a6b81397c18c1
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

SLC8A1 SERINC1 SCN2A SCN9A DAAM1

5.63e-05200915db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

SLC8A1 SERINC1 SCN2A SCN9A DAAM1

5.63e-0520091530a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SLC26A7 PCNX4 SCN2A

1.79e-0413791481cdb216e6c81acf9c2072f9d39e1a42612e1258
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC7A3 SCN4A SCN9A TAAR9

1.79e-041379145cb84392e4483f50e09fb7395e2ec98f3eb6ecf3
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Dcn|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADRA1D MYO15B ATP2C2

2.05e-0456913821d5939c7c8d3ebbb2e0c64d0197f639f02278a
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Dcn-Excitatory_Neuron.Slc17a7.Dcn-Pou3f1_(Anterior_Subiculum,_proximal_to_CA1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADRA1D MYO15B ATP2C2

2.05e-0456913a762127a14327e8ab55a3e25ec26a84cc3210693
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SCN2A HRH4 OR8D4

2.11e-04143914990844ca674d30b2924c74b45bed4fdfb8463fa7
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B SCN9A ADGRV1 USH2A

2.23e-0414591496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SLC26A7 SCN2A OR8D4

2.23e-041459149964d6d3769be2f35d86268fe044cecd1d5a1616
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPR82 SCN9A SLC30A4 CLDN1

2.23e-04145914997bd540c43725a85ca97e4b79ebe0d336860287
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Sst_(Striatum,_interneuron)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC26A7 ATP1A4 FASLG

2.40e-04599130946b53be12a9926d876c75ddf5dec414a4f8063
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Sst_(Striatum,_interneuron)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC26A7 ATP1A4 FASLG

2.40e-04599135da8beaf3c690861d5561ae40d4ff7c2d3732ef4
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Sst_(Striatum,_interneuron)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC26A7 ATP1A4 FASLG

2.40e-04599131c26fabefafd4ce05f21750ae69895c488ea1a11
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Sparc_(Sparc)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ATP1A4 FXYD3 SLC22A12

2.52e-0460913f54674b9995680c7f201cf1142e7f9327960f42f
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Sparc_(Sparc)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ATP1A4 FXYD3 SLC22A12

2.52e-046091366542df5eb7080a879b02c306a7ccbd9f67bf54d
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Sparc_(Sparc)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ATP1A4 FXYD3 SLC22A12

2.52e-0460913746a1ac6e666d1d53a4bea8f103642f2fa42e725
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SLC26A7 PCNX4 SCN2A

2.53e-0415091487968ce885a4959616f0321f58517fe8029ba1b1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cyp26b1_(SNc/VTA)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR82 SLC5A9 FASLG

2.65e-0461913b3f34ed4433aa8a8a9dea9e47fb98620b4e80a6c
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cyp26b1_(SNc/VTA)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR82 SLC5A9 FASLG

2.65e-0461913f41f1e770a5672f32cc5ccec3e33902c40f3fb1b
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC8A1 HSD17B3 SLC30A4 BDKRB2

2.80e-0415491416fdafb5c64d2db321554f87129a962d113f1668
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O1-Trf|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADGRV1 SLC23A1 BDKRB2

2.91e-046391383e1c91f830aadaf13e13254ce30189fd434bcc9
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendroyte.Trf.Il33_(Il33)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADGRV1 SLC23A1 BDKRB2

2.91e-0463913f2532b1aa117eea550f0ae0b599780c4fe621407
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O1|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADGRV1 SLC23A1 BDKRB2

2.91e-04639130643435edf3280daf38c950e5bec287a9d5cb517
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendroyte.Trf.Il33_(Il33)|Cerebellum / BrainAtlas - Mouse McCarroll V32

ADGRV1 SLC23A1 BDKRB2

2.91e-046391371c3afda6534401320791b714e3e2fe83094c914
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUL4A C1QA HRH4 DSE

2.94e-041569145caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUL4A C1QA HRH4 DSE

2.94e-04156914758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCell-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CLDN14 ABCB9 PLA2G2A EBF1

2.94e-04156914f0c4d9d58365b0ae8e10ba1aaf3847fb3f98c7ad
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 GAL3ST4 ATP13A2 NCAPG2

3.01e-04157914ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell368C-Fibroblasts-Fibroblast-F|368C / Donor, Lineage, Cell class and subclass (all cells)

SCN5A EBF1 SLC30A4 SLC23A2

3.01e-0415791474038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell368C-Fibroblasts-Fibroblast-F-|368C / Donor, Lineage, Cell class and subclass (all cells)

SCN5A EBF1 SLC30A4 SLC23A2

3.01e-04157914982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCB9 CD37 HRH4 FASLG

3.16e-041599144750ba9ca06ed97b18df3c74eeb51d3ac8763f63
ToppCellwk_08-11-Hematologic-Meg-ery-Platelet|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SCN11A AQP10 TAS2R50 SLC16A12

3.24e-04160914e0591f95f3f47ffbe013ebbebf6bed8c7c344732
ToppCelldroplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR82 C1QA SLC46A1 DSE

3.31e-04161914f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OVOS2 SLC5A9 TAS2R50 SLC30A4

3.31e-041619147c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A ABCB9 SCN5A FASLG

3.31e-04161914334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A ABCB9 SCN5A FASLG

3.31e-0416191481d44438e4be4e68a59247e62f02026301a8a0c5
ToppCelldroplet-Lung-nan-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR82 C1QA SLC46A1 DSE

3.31e-04161914110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1B SCN9A ADGRV1 USH2A

3.39e-04162914bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-13|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD37 EBF1 TAS2R50 OR2T11

3.39e-0416291428b3a6ae5519a267eefb70436d3190a387d027b9
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 GAL3ST4 ATP13A2 NCAPG2

3.47e-041639148dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 GAL3ST4 ATP13A2 NCAPG2

3.47e-04163914fd243ca223079033be480a24817a399f281fa4d4
DrugZonisamide

CA9 SCN11A SCN2A SCN4A SCN5A SCN9A

4.12e-1117916DB00909
DrugCalcium

CACNA1A CACNA1B PROKR1 SLC8A1 ADRA1D MTOR SCN9A PLA2G2A HRH4 FASLG SEC61A1 SLC23A2 BDKRB2

8.10e-084939113ctd:D002118
Druglamotrigine

CACNA1A CACNA1B SCN2A SCN4A SCN5A SCN9A FASLG

4.22e-07116917CID000003878
Drugepoxiconazole

CACNA1A CACNA1B YIPF5 OST4 TNKS2 SEC61A1 SLC23A2 SLC23A1 SLC16A12 STT3A

1.09e-063419110ctd:C109476
Drugsysthane

ABCB9 DAAM1 ADGRV1 HSD17B3 FASLG CLDN1

4.04e-06105916ctd:C446685
Drugverapamil

CACNA1A CACNA1B ADRA1D ABCB7 ABCB9 SLC22A5 SCN4A ATP2C2 SCN5A SCN9A ABCA7

4.12e-064909111CID000002520
Drugpyraclofos

CACNA1A CACNA1B SCN2A SCN4A SCN5A SCN9A

4.27e-06106916CID000093460
Drugsodium

SLC8A1 SLC7A3 SLC26A7 MTOR SCN2A SLC22A5 SCN4A ATP2C2 SCN5A SCN9A SLC46A1 ATP1A4 FXYD3 SLC23A2 SLC23A1

4.74e-069449115CID000000923
Drugsynthetic pyrethrins

CACNA1A CACNA1B SLC22A18 SCN4A SCN9A

9.65e-0671915CID000002982
Drugprobenecid

SLC22A5 SLC46A1 SLC23A2 SLC23A1 SLC16A12 SLC22A12

1.01e-05123916CID000004911
Drugsotalol

ADRA1D SCN4A SCN5A SCN9A SLC25A29

1.11e-0573915CID000005253
Drugbepridil

CACNA1A CACNA1B SCN4A ATP2C2 SCN5A SCN9A

1.16e-05126916CID000002351
Drugsipatrigine

CACNA1B SCN2A SCN4A SCN9A

1.43e-0537914CID000060803
Drugmu-conotoxin KIIIA, Conus kinoshitai

SCN2A SCN4A

1.58e-052912ctd:C502265
DrugRanolazine

SCN5A SCN9A

1.58e-052912DB00243
DrugFlecainide

SCN4A SCN5A

1.58e-052912DB01195
Drug6-deoxy-6-bromoascorbic acid

SLC23A2 SLC23A1

1.58e-052912ctd:C068572
DrugSodium

SCN11A SLC8A1 SCN2A SCN5A SCN9A

2.20e-0584915ctd:D012964
DrugVerapamil

CACNA1A CACNA1B SCN5A

3.33e-0516913DB00661
Drugnitrendipine

CACNA1A CACNA1B SLC25A29 SLC39A14 SLC30A4

4.63e-0598915CID000004507
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN4A SCN9A

4.73e-053912ctd:C561228
Drugmoricizine

SCN4A SCN5A SCN9A

4.83e-0518913CID000034632
DrugScorpion Venoms

SCN2A SCN4A SCN9A

4.83e-0518913ctd:D012604
Drugtetradotoxin

CACNA1A CACNA1B SCN11A ADRA1D SCN2A SCN4A SCN5A SCN9A HRH4

5.42e-05428919CID000020382
DrugAC1NPPZW

MTOR SCN2A SCN4A SCN5A SCN9A

5.87e-05103915CID005183170
Drugcyproconazole

YIPF5 OST4 TNKS2 SEC61A1 SLC23A2 SLC23A1 SLC16A12 STT3A

6.07e-05336918ctd:C093628
Drugcimetidine

SLC22A5 HRH4 SLC23A2 SLC23A1 SLC16A12 SLC22A12

8.32e-05179916CID000002756
Drugcarbamazepine

ABCB7 SCN2A SLC22A5 SCN4A SCN5A SCN9A

8.32e-05179916CID000002554
DrugNSC7524

CACNA1A CACNA1B SCN2A SCN4A SCN5A SCN9A

9.12e-05182916CID000005657
DrugAC 110

CACNA1A CACNA1B

9.43e-054912CID000022860
DrugFospropofol

SCN2A SCN4A

9.43e-054912DB06716
DrugLidocaine

SCN5A SCN9A

9.43e-054912DB00281
Drug1,4-dimethylpiperazine

SLC8A1 SCN5A

9.43e-054912CID000007818
DrugPropofol

SCN2A SCN4A

9.43e-054912DB00818
Drugmibefradil

CACNA1A CACNA1B SCN5A SCN9A

1.26e-0464914CID000060662
DrugMulticide

SCN2A SCN4A SCN9A

1.33e-0425913CID000024365
Drugmexiletine

CACNA1B SCN4A SCN5A SCN9A

1.42e-0466914CID000004178
DrugDicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A

CA9 TAS2R4 SLC8A1 ADCK2 HSD17B3 SLC23A2

1.45e-041989163941_UP
DrugPF-00539758-00 [351321-34-1]; Down 200; 10uM; MCF7; HT_HG-U133A

CA9 ADRA1D ABCB9 HSD17B3 FASLG BDKRB2

1.49e-041999166416_DN
DrugS 8510

CACNA1A CACNA1B

1.57e-045912CID005488383
Drugdibucaine

CACNA1B SCN4A SCN5A SCN9A

1.60e-0468914CID000003025
DrugAC1L1MOZ

SCN4A SCN5A SCN9A

1.69e-0427913CID000031958
Drugnefopam

SLC22A18 SCN4A SCN9A

1.69e-0427913CID000004450
Drugpotassium

CACNA1A CACNA1B SLC8A1 SLC7A3 SCN2A SCN4A ATP2C2 SCN5A SCN9A HRH4 ATP1A4 FXYD3 BDKRB2

1.81e-0410089113CID000000813
Drugencainide

SCN4A SCN5A SCN9A

1.88e-0428913CID000048040
DrugDPI 201-106

SCN4A SCN5A SCN9A

1.88e-0428913CID000005190
Drugflecainide

SCN11A SCN4A SCN5A SCN9A

1.89e-0471914CID000003355
DrugBarium

CACNA1A CACNA1B SLC8A1 SLC22A12

2.00e-0472914ctd:D001464
Diseaseepilepsy (implicated_via_orthology)

CACNA1A CACNA1B SCN11A SCN2A SCN4A SCN5A SCN9A C1QA ATP1A4 BDKRB2

3.89e-111638410DOID:1826 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN2A SCN4A SCN5A SCN9A

4.13e-1110845DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN2A SCN4A SCN5A SCN9A

4.13e-1110845DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN2A SCN4A SCN5A SCN9A

1.29e-1012845DOID:0060170 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN2A SCN9A ADGRV1

1.85e-069843C3502809
DiseaseManganese Poisoning

SLC39A14 ATP13A2 SLC39A8

7.92e-0614843C0677050
DiseasePrimary Erythermalgia

SCN11A SCN9A

2.40e-053842C0014805
DiseaseX-24431 measurement

SLC23A2 SLC23A1

2.40e-053842EFO_0800882
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN9A

2.40e-053842C1833661
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1B

2.40e-053842DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1B

4.79e-054842DOID:6364 (implicated_via_orthology)
Diseasetartronate (hydroxymalonate) measurement

SLC23A2 SLC23A1

4.79e-054842EFO_0800944
Diseaseextraversion measurement

SLC23A2 SLC23A1

1.19e-046842EFO_0007913
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

CACNA1A ATP1A4

1.67e-047842DOID:0060178 (implicated_via_orthology)
DiseaseCongenital Pain Insensitivity

SCN11A SCN9A

1.67e-047842C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN9A

1.67e-047842C0020075
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1B

1.67e-047842DOID:0050951 (implicated_via_orthology)
DiseasePruritus

SCN9A HRH4

2.22e-048842C0033774
DiseaseCardiomyopathy, Dilated

SLC22A5 SCN5A FASLG

3.51e-0448843C0007193
Diseaselymphocyte measurement

EBF1 ABCA7 SLC39A8 STT3A

3.55e-04117844EFO_0803546
Diseasethreonate measurement

SLC23A2 SLC23A1

3.55e-0410842EFO_0021032
DiseaseCardiomyopathies

SLC22A5 SCN5A FASLG BDKRB2

5.28e-04130844C0878544
DiseaseInfantile Severe Myoclonic Epilepsy

SCN2A SCN9A

6.12e-0413842C0751122
Diseaseascorbic acid 3-sulfate measurement

SLC23A2 SLC23A1

7.13e-0414842EFO_0800173
DiseaseNeoplasm of lung

SLC22A18 FASLG

7.13e-0414842cv:C0024121
DiseaseLung cancer

SLC22A18 FASLG

7.13e-0414842cv:C0242379
DiseaseLUNG CANCER

SLC22A18 FASLG

7.13e-0414842211980
Diseaseglycerate measurement

SLC23A2 SLC23A1

8.21e-0415842EFO_0021029
DiseaseTremor, Rubral

CACNA1A ABCB7

9.36e-0416842C0750940
DiseaseAtaxia, Appendicular

CACNA1A ABCB7

9.36e-0416842C0750937
DiseaseAtaxia, Motor

CACNA1A ABCB7

9.36e-0416842C0278161
Diseasevitamin C measurement

SLC23A2 SLC23A1

9.36e-0416842EFO_0600003
DiseaseAtaxia, Sensory

CACNA1A ABCB7

9.36e-0416842C0240991
DiseaseAbnormal coordination

CACNA1A ABCB7

9.36e-0416842C0520966
DiseaseAtaxia, Truncal

CACNA1A ABCB7

9.36e-0416842C0427190
DiseaseS-adenosylhomocysteine measurement

CACNA1B ADRA1D

1.06e-0317842EFO_0010531
Diseaseportal hypertension (implicated_via_orthology)

MTOR BDKRB2

1.33e-0319842DOID:10762 (implicated_via_orthology)
Diseasemyelodysplastic syndrome (is_marker_for)

SLC22A5 FASLG

1.47e-0320842DOID:0050908 (is_marker_for)
Diseasepalmitoylcarnitine measurement

SLC22A5 ATP1A4

1.62e-0321842EFO_0021044
Diseasenucleus accumbens volume

USH2A SLC39A8

1.78e-0322842EFO_0006931
Diseaseanxiety disorder (implicated_via_orthology)

SCN2A SCN9A

1.78e-0322842DOID:2030 (implicated_via_orthology)
DiseaseRespiratory Hypersensitivity

SLC39A14 SLC30A4

1.78e-0322842C0035228
DiseaseAllodynia

PROKR1 SCN11A BDKRB2

1.80e-0384843C0458247
DiseaseMechanical Allodynia

PROKR1 SCN11A BDKRB2

1.80e-0384843C2936719
DiseaseHyperalgesia, Secondary

PROKR1 SCN11A BDKRB2

1.80e-0384843C0751212
DiseaseHyperalgesia, Primary

PROKR1 SCN11A BDKRB2

1.80e-0384843C0751211
DiseaseHyperalgesia, Thermal

PROKR1 SCN11A BDKRB2

1.80e-0384843C0751214
DiseaseTactile Allodynia

PROKR1 SCN11A BDKRB2

1.80e-0384843C0751213
DiseaseHyperalgesia

PROKR1 SCN11A BDKRB2

1.80e-0384843C0020429
DiseaseDystonia

CACNA1A SLC46A1 ATP13A2

1.92e-0386843C0013421
DiseaseNephritis, Interstitial

SEC61A1 SLC16A12

2.12e-0324842C0027707
Diseasearachidonic acid measurement

CACNA1A ADRA1D

2.30e-0325842EFO_0006808
DiseaseAtaxia

CACNA1A ABCB7

2.30e-0325842C0004134
DiseaseBipolar Disorder

CACNA1A CACNA1B SCN2A PLA2G2A BDKRB2 TAAR6

2.43e-03477846C0005586
Diseaseinflammatory biomarker measurement

SLC8A1 C1QA

2.49e-0326842EFO_0004872
Diseasehearing impairment

CLDN14 ADGRV1 USH2A

2.79e-0398843C1384666

Protein segments in the cluster

PeptideGeneStartEntry
IGSFFMLNLVLGVLS

CACNA1A

346

O00555
EVFTNMLLNVVGFLL

BDKRB2

221

P30411
NFASIVFAIMVLEGL

ADCK2

586

Q7Z695
GLFQVVSGGMVLQLQ

C1QA

196

P02745
IKFISGNLGFLNEMI

ARMC2

401

Q8NEN0
SNFTLQLVTVMLVGG

ADGRV1

4846

Q8WXG9
AEFLGVFVLMLLTQG

AQP10

26

Q96PS8
IIGSFFMLNLVLGVL

CACNA1B

341

Q00975
FMLNLVLGVLSGEFA

CACNA1B

346

Q00975
VVFALLGMQLFGGQF

CACNA1B

621

Q00975
KQLTLFSFGIIGLIM

ATP2C2

296

O75185
LFIGINGSMATFVLE

ABCA7

1656

Q8IZY2
GLLFAVTSVAFLVQM

CA9

421

Q16790
LMIAVFGGTLQVTQD

LRRC8A

36

Q8IWT6
MIFGLLQAHGNLVNF

PLA2G2A

11

P14555
ELLIFVIGGFNMVAT

OR8D4

196

Q8NGM9
EIGLAFNILGMVVFA

SLC46A1

336

Q96NT5
AMISQIAGLIGTTFI

GPR82

196

Q96P67
GLLMTFLVVIFLKGN

MAGEB5

131

Q9BZ81
GLLLVILGVIFMNGN

MAGED1

561

Q9Y5V3
NSQAIVGYGLMILLI

PCNX4

386

Q63HM2
TQLNELLLFAVGFIM

OR3A2

201

P47893
IFGNNLGALAMFCVL

DSE

101

Q9UL01
GFMQSIQNLGLAIIS

MFSD1

391

Q9H3U5
FTVVGDILGLAMQNL

OVOS2

936

Q6IE36
ALGVFMTIGFALQLL

GAL3ST4

21

Q96RP7
QLAIFANMLGVSLFL

OST4

6

P0C6T2
EMLGQSQLQLVGSLF

MYO15B

176

Q96JP2
IMSFINAVLSQGAGV

DAAM1

281

Q9Y4D1
LGLVTLNFVGAFMLE

ATP13A2

1121

Q9NQ11
MANAGLQLLGFILAF

CLDN1

1

O95832
VQLLGFLLSFLGMVG

CLDN14

6

O95500
QALFLIQGMFVSLFP

EI24

181

O14681
VSLFQTLVLLMFNEG

CUL4A

591

Q13619
NFFDGLQVIFGTMLV

EBF1

286

Q9UH73
LMGLTFINALVFGVQ

SLC25A29

66

Q8N8R3
MGDVLEQFFILTGLL

HSD17B3

1

P37058
SNIFLLQMFIGVVDI

SLC22A12

376

Q96S37
GGLGRFQILQMVFLI

SLC22A25

11

Q6T423
FVVLFVLVGMGQISN

SLC22A5

196

O76082
ALFLGGSVLLFMQLV

SLC22A5

406

O76082
IIQNLGLLTGFTIMV

SLC39A14

466

Q15043
KVFTGVNLLVLGFVM

SLC7A3

191

Q8WY07
VNLLVLGFVMISGFV

SLC7A3

196

Q8WY07
FGMLLLLFATQITLG

CD37

91

P11049
VFLGAVTANLVMIFL

OR2T11

31

Q8NH01
LTFGINNCFLLTVMG

OR10J3

106

Q5JRS4
DIVTIFNLIQMNGGA

MINAR1

86

Q9UPX6
GAIREFLFQQLGMLV

MTOR

1006

P42345
MQKVTLGLLVFLAGF

FXYD3

1

Q14802
AFAIMLGNALVILAF

HRH4

26

Q9H3N8
EFIISMLGNVFIGLV

TAS2R42

16

Q7RTR8
ILIMVLFVLGNFANG

TAS2R50

11

P59544
LSLGSGFLFQVIEML

USH2A

6

O75445
LFNGAQKLFGMIITI

SEC61A2

111

Q9H9S3
LSVFALVGLQLFMGN

SCN4A

261

P35499
FGAVLAVFGNLLVMI

TAAR6

41

Q96RI8
LIMGIGIFLFICANA

TMEM200C

171

A6NKL6
FGAVLAAFGNLLVMI

TAAR9

41

Q96RI9
QQAAFLMSILGVIDI

SLC16A12

316

Q6ZSM3
LSVFALIGLQLFMGN

SCN5A

261

Q14524
EEMLQVGNLVFTGIF

SCN5A

746

Q14524
LSVFALIGLQLFMGN

SCN9A

256

Q15858
LGTILSMQISFVGFQ

STT3A

246

P46977
VGGALVLMFLGFQDV

SLC5A9

221

Q2M3M2
LGMFVLQLGVLSTFL

SLC26A10

131

Q8NG04
SFFGLLQMVTQGLVI

SLC22A18

281

Q96BI1
GMAGAFCFILIQLVL

SERINC1

156

Q9NRX5
TVGDLVMVNGLLFQL

ABCB7

406

O75027
ISGQMTSGNLIAFII

ABCB9

436

Q9NP78
VFLAAFILMAVAGNL

ADRA1D

101

P25100
FQQGMRNKVLIFGIL

ATP1A4

951

Q13733
LQRSLGIMQTVKGFF

NCAPG2

906

Q86XI2
GIMLVCGIGNFIFIA

PROKR1

71

Q8TCW9
MLQFLLGFTLGNVVG

STMP1

1

E0CX11
LQDNLIVVAGVFMGI

TSPAN17

231

Q96FV3
GLMAAFFALAALVQV

TMEM220

11

Q6QAJ8
LNLMLVVSGVAIFVN

TMEM143

281

Q96AN5
GMITAVGLSNLQFID

SLC23A2

496

Q9UGH3
FGMITAVGLSNLQFV

SLC23A1

436

Q9UHI7
LFNGAQKLFGMIITI

SEC61A1

111

P61619
SIVLLGLIATGMFQF

EXT2

31

Q93063
VFALIGLQLFMGNLR

SCN2A

261

Q99250
LAEQMFQGIILFSAI

SPCS1

86

Q9Y6A9
METVLQVLLGILGFQ

TRAV34

1

A0A0B4J273
AGSIFITIFGNLAMI

TAAR2

51

Q9P1P5
FVVGMIGAALFILIQ

SERINC3

161

Q13530
IISLQGFTALQMGNE

TNKS2

461

Q9H2K2
IFISALAMEGQQLLV

YIPF5

226

Q969M3
LVALVGLGLGMFQLF

FASLG

91

P48023
FQGGVLTARLFKMQV

nan

566

Q3C1V9
MFGINIVFIPSALAA

TMEM245

731

Q9H330
VAVNVIMGFLLNQSG

SLC30A4

226

O14863
QNAGMLTGFTAILLI

SLC39A8

436

Q9C0K1
IFALVGQQLFMGSLN

SCN11A

266

Q9UI33
GVIQVAMFVLQLGSA

SLC26A7

156

Q8TE54
ILLSQIMVGFLGNFF

VN1R3

11

Q9BXE9
LNFVGIIMNLFITVV

TAS2R4

16

Q9NYW5
IVGSAAFNMFIIIAL

SLC8A1

171

P32418