Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionunmethylated CpG binding

KDM2B FBXL19

9.75e-0510302GO:0045322
DomainMAP6

MAP6 MAP6D1

2.49e-062302IPR007882
DomainPHD_4

KDM2B FBXL19

7.48e-063302PF16866
Domainzf-CXXC

KDM2B FBXL19

1.36e-0411302PF02008
DomainZnf_CXXC

KDM2B FBXL19

1.36e-0411302IPR002857
DomainZF_CXXC

KDM2B FBXL19

1.36e-0411302PS51058
DomainLeu-rich_rpt_Cys-con_subtyp

KDM2B FBXL19

4.19e-0419302IPR006553
DomainLRR_CC

KDM2B FBXL19

4.19e-0419302SM00367
DomainFBOX

KDM2B FBXL19

3.15e-0352302SM00256
DomainF-box

KDM2B FBXL19

5.17e-0367302PF00646
DomainFBOX

KDM2B FBXL19

5.95e-0372302PS50181
DomainF-box_dom

KDM2B FBXL19

6.44e-0375302IPR001810
DomainZnf_PHD-finger

KDM2B FBXL19

7.12e-0379302IPR019787
DomainPHD

KDM2B FBXL19

8.96e-0389302SM00249
DomainZnf_PHD

KDM2B FBXL19

9.35e-0391302IPR001965
PathwayREACTOME_SIGNALING_BY_FGFR1

FGF23 PLCG1 SPRED2

7.07e-0550233MM15255
PathwayREACTOME_SIGNALING_BY_FGFR1

FGF23 PLCG1 SPRED2

7.96e-0552233M27530
PathwayREACTOME_FGFRL1_MODULATION_OF_FGFR1_SIGNALING

FGF23 SPRED2

1.96e-0413232M27540
PathwayREACTOME_FGFRL1_MODULATION_OF_FGFR1_SIGNALING

FGF23 SPRED2

1.96e-0413232MM15262
PathwayREACTOME_SIGNALING_BY_FGFR

FGF23 PLCG1 SPRED2

2.57e-0477233MM14722
PathwayREACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR4

FGF23 PLCG1

2.64e-0415232M27509
PathwayREACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR4

FGF23 PLCG1

2.64e-0415232MM15235
PathwayREACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR1

FGF23 PLCG1

3.01e-0416232M48007
PathwayREACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR1

FGF23 PLCG1

3.01e-0416232MM15233
PathwayREACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR2

FGF23 PLCG1

3.41e-0417232MM15234
PathwayREACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE_FGFR2

FGF23 PLCG1

3.83e-0418232M27508
PathwayREACTOME_SIGNALING_BY_FGFR

FGF23 PLCG1 SPRED2

3.93e-0489233M1090
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR3

FGF23 PLCG1

6.88e-0424232MM15246
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR3

FGF23 PLCG1

7.47e-0425232M27520
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR4

FGF23 PLCG1

8.08e-0426232MM15249
PathwayREACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

PLCG1 TRBV12-4

8.72e-0427232MM14809
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR4

FGF23 PLCG1

8.72e-0427232M27523
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR2

FGF23 PLCG1

9.38e-0428232MM15241
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR2

FGF23 PLCG1

1.08e-0330232M27515
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1

FGF23 PLCG1

1.08e-0330232MM15236
PathwayREACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR1

FGF23 PLCG1

1.15e-0331232M27510
PathwayREACTOME_SIGNALING_BY_FGFR1_IN_DISEASE

FGF23 PLCG1

1.73e-0338232M27536
PathwayREACTOME_SIGNALING_BY_FGFR3

FGF23 PLCG1

1.82e-0339232MM15257
PathwayREACTOME_SIGNALING_BY_FGFR3

FGF23 PLCG1

1.91e-0340232M27532
PathwayREACTOME_SIGNALING_BY_FGFR4

FGF23 PLCG1

1.91e-0340232MM15258
PathwayREACTOME_SIGNALING_BY_FGFR4

FGF23 PLCG1

2.01e-0341232M27533
Pubmed

STOP-like protein 21 is a novel member of the STOP family, revealing a Golgi localization of STOP proteins.

MAP6 MAP6D1

5.23e-06433216837464
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

KDM2B FBXL19

3.91e-051033229276034
Pubmed

Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.

PLCG1 PLXNB1

6.77e-051333219805522
Pubmed

PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth.

KDM2B FBXL19

1.32e-041833228614300
Pubmed

Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.

MAP3K5 ADGRB1

1.48e-041933212543931
Pubmed

Identification of the COMM-domain containing protein 1 as specific binding partner for the guanine-rich RNA sequence binding factor 1.

MAP6 ERO1A

3.74e-043033232645484
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

BACE1 FGF23 PLCG1 MAP3K5

4.08e-0437133425241761
Pubmed

T-Cell Signaling in HIV-1 Infection.

PLCG1 MAP3K5

4.25e-043233223986795
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PERP BACE1 CCDC47 EMILIN1

7.10e-0443033416303743
Pubmed

TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.

PLCG1 PLXNB1

9.19e-044733235462405
Pubmed

Identification of NPM-ALK interacting proteins by tandem mass spectrometry.

PLCG1 MAP3K5

9.19e-044733214968112
CytobandEnsembl 112 genes in cytogenetic band chr6q23

PERP MAP3K5

3.54e-03119342chr6q23
GeneFamilyZinc fingers CXXC-type

KDM2B FBXL19

5.46e-0512172136
GeneFamilyF-box and leucine rich repeat proteins

KDM2B FBXL19

1.73e-0421172558
GeneFamilyPHD finger proteins

KDM2B FBXL19

3.17e-039017288
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP MREG GNA15 HSD17B2

1.08e-05187334aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Trm_Th1/Th17|Liver / Manually curated celltypes from each tissue

PERP GNA15 PLCG1 IL9R

1.27e-05195334480cc62ee1e5b1aaf6b62be6e5afd7a81236a1b0
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Trm_Th1/Th17|Lung / Manually curated celltypes from each tissue

PERP CD48 PLCG1 IL9R

1.37e-051993341acf522a5d296042fe9f1cb47c1a06fc22da75a3
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Fos_(Layer_5,_medial_posterior_cortex_(Retrosplenial_cortex_(RSG),_subiculum))|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FGF23 HSD17B2 HTR6

3.78e-0588333e38bee67177403cc06714b98e824a17055204586
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Fos_(Layer_5,_medial_posterior_cortex_(Retrosplenial_cortex_(RSG),_subiculum))-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FGF23 HSD17B2 HTR6

3.78e-0588333a909ea58f17716de9cf2486e648b89298b96e0d1
ToppCellLPS-IL1RA-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSD17B2 PLXNB1 MAP3K5

9.06e-051183336053e19d040fb394f9c270361af07b0c5a4d47db
ToppCellLPS-IL1RA-Myeloid-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSD17B2 PLXNB1 MAP3K5

9.06e-05118333811e8521129914eef46785a4227c1860e77d9096
ToppCellMild/Remission-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HTR6 CPLANE1 MAP6

9.76e-0512133368940a552233d255b90ce5a081339c0d9d46ab02
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c10-IFNG|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLCG1 FBXL19 SLC26A1

1.10e-04126333d19382597ce5c6546731ac1fd33c7dcb7916b2ea
ToppCellTCGA-Brain-Recurrent_Tumor-Glioblastoma|TCGA-Brain / Sample_Type by Project: Shred V9

FGF23 TRBV12-4 ERO1A

1.44e-04138333142e4692d7f97ce157ed70fcb2e4a63febfbb6e4
ToppCellTCGA-Brain-Recurrent_Tumor-Glioblastoma-Primary_GBM|TCGA-Brain / Sample_Type by Project: Shred V9

FGF23 TRBV12-4 ERO1A

1.44e-04138333728e0576526c4525ba2038921425ab3e7d321ce2
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MREG CCDC47 MAP3K5

1.63e-0414433376c0e551864c4faab7528c4ecf1a40d7ea60569f
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD48 GNA15 KCNK12

2.03e-04155333f3489a548a2c0cc2d9117ff85865c6089ea0835d
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD48 GNA15 KCNK12

2.03e-041553330e24e767a3895d31d34cabeaca0354aadae34e44
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-ILC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GNA15 KCNK12 IL9R

2.27e-04161333a3318e738836eb1c5babe1a5d2dd7fa34d732662
ToppCell356C-Lymphocytic-ILC-ILC-3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MREG PLXNB1 MAP3K5

2.35e-041633332dbdcbc4c187aad3db837d191cc78662a75dd0b5
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17|bone_marrow / Manually curated celltypes from each tissue

PERP MREG IL9R

2.35e-041633334d1fd0b1246833723b938eca0cb246e937380e12
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MREG MAP6 CEP72

2.39e-0416433378de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD48 ERO1A IL9R

2.44e-04165333004d793bf5bb6fb3b7bf38baf11b32d46375fe4d
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MREG KDM2B SLC26A1

2.48e-0416633375d719617c61409860f298ce91cbe3a0aafa0553
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MREG KDM2B GNA15

2.48e-04166333da10d0be6b616199d49dd922591c2901f9681583
ToppCellfacs-Aorta-Heart-24m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD48 KDM2B GNA15

2.52e-04167333b85fd7ab21c80470bca804c788ce49a2bce763f8
ToppCell356C-Myeloid-Dendritic-cDC_activated|356C / Donor, Lineage, Cell class and subclass (all cells)

MREG KDM2B SPRED2

2.52e-0416733343a9375fdbafd7450c553e4620e21537e08639dd
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD48 KCNK12 TRBV12-4

2.52e-04167333484de3ca4a905067c18d06995601479eef8fc15e
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDM2B HTR6 ADGRB1

2.52e-041673338b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD48 GNA15 IL9R

2.52e-04167333eed22d1a17aab84dacb1a488528bae9389644cb9
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD48 GNA15 IL9R

2.61e-04169333b08567ecfa3f8d83e7990330fc1b27f0bb7e75a1
ToppCellBronchial_Brush-Immune-B_cells|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CD48 KCNK12 IL9R

2.61e-04169333dc388f660f69e37e517bf3243daf071ab138ee6e
ToppCellILEUM-non-inflamed-(3)_mature_DC|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MREG KDM2B ADGRB1

2.66e-0417033360151394460e6f27a42fab434e8b7b2adc78b128
ToppCelldroplet-Limb_Muscle-nan-21m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD48 MREG IL9R

2.75e-0417233362734d231290ca725276dc62faa2ac87bd1b37b8
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD48 GNA15 IL9R

2.75e-04172333282017db72d0537ac82aecc69393ccde9590be60
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MREG SPRED2 MAP6

2.80e-0417333309a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MREG SPRED2 MAP6

2.80e-04173333bfec038a6783f166240da4861e100643c6ea80a5
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD48 KDM2B GNA15

2.80e-04173333f66aebceb3eb389bc5ff6c0b398d6f4e9959a14f
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PERP GNA15 HSD17B2

2.85e-0417433399d7421ad5eafe7751ef90698a92f683aa33bca8
ToppCelldroplet-Kidney-nan-3m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD48 KDM2B GNA15

2.85e-041743330e541581df2d4249270b28ceded6298329013580
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD48 GNA15 KCNK12

2.90e-04175333db6be3e9e339918418fcaf9001ea15207aa6c993
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD48 GNA15 KCNK12

2.90e-041753338acac10c9eedccebcf3a3fe31bfee35afa54579f
ToppCellT_cells-Tph_and_Tfh|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

GNA15 MAP6 PLXNB1

2.95e-0417633356c055488e34605d32562571a2fee621b47c9441
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

BACE1 EMILIN1 PRIMA1

2.95e-04176333852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

BACE1 EMILIN1 PRIMA1

2.95e-04176333d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MREG KDM2B ADGRB1

2.99e-04177333aa56129d2d5a73a10e33b7162233a4d9337ee535
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD48 GNA15 IL9R

2.99e-041773339828504591599619649d41a78daf7c052729c669
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MREG KDM2B ADGRB1

2.99e-04177333d78a6003ce2d15d7771ae385de252eec7e3c3eea
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MREG KDM2B ADGRB1

2.99e-0417733370ca5b6fde2e38af1eb88a7d6e8746edba298191
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP MREG CEP72

3.04e-04178333de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD48 GNA15 IL9R

3.09e-04179333b8bc03f60a7ac76ea6ee90d0512f0dc1d1d2a087
ToppCellMild-Lymphoid-T-innate_T|Mild / Condition, Lineage, Cell class and cell subclass

PERP CD48 PLCG1

3.09e-04179333abc0fbe101a464a2c85755a974a3d5c2b968fe46
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD48 KDM2B KCNK12

3.09e-04179333db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MREG KDM2B SPRED2

3.15e-0418033332d871738a24071b70084a7e80148a516110c78b
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP6 EMILIN1 PRIMA1

3.15e-04180333f2f6e83127a4a415e65c76a35efa8175fbd5b5d9
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MREG KDM2B SPRED2

3.15e-04180333067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCellfacs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNB1 MAP6D1 ADGRB1

3.15e-04180333c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCell10x5'-Lung-Myeloid_Dendritic-migDC|Lung / Manually curated celltypes from each tissue

MREG KDM2B SPRED2

3.15e-04180333e9e8992deb0beeee5548910e4616e7c990763d99
ToppCellfacs-Marrow-B-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNB1 MAP6D1 ADGRB1

3.15e-0418033307ac979b21be2425294d9818c48b5a1e6f014c19
ToppCellfacs-Heart-RA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP HSD17B2 PLXNB1

3.20e-04181333c68d272eb41f81bd8ea4d0360733a2396bc87037
ToppCellfacs-Heart-RA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP HSD17B2 PLXNB1

3.20e-041813335e5eb89f224ee48065a328ade030cbc4dcdcac12
ToppCellwk_20-22-Hematologic-Myeloid-aDC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MREG KDM2B GNA15

3.20e-041813338f7e5c310f4cdc4b2fb54fea950d01e56bd298e1
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACE1 KCNK12 EMILIN1

3.25e-041823338b16a13d8606d21a7a9ce1175237e9b4cf832ee0
ToppCelldroplet-Marrow-nan-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM2B KCNK12 EMILIN1

3.30e-0418333324db9cc717e651586317c6a8e03a3401651273c1
ToppCelldroplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM2B KCNK12 EMILIN1

3.30e-0418333392ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACE1 KCNK12 EMILIN1

3.41e-041853333f1aa91efae2d00320d126087cce1431ad5f26ea
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK12 EMILIN1 ERO1A

3.41e-0418533353854a9ec87c24c360541c83d86d8fafb303ad58
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK12 EMILIN1 ERO1A

3.41e-04185333a61fc7a3700a1efcf640bef7680c0443ee148a46
ToppCellPBMC-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

MREG SPRED2 MAP6

3.41e-041853334b5a7450fed912f340da16065c1e65d626dbe8d1
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|normal_Lung / Location, Cell class and cell subclass

MREG KDM2B SPRED2

3.46e-041863330987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

MREG KDM2B SPRED2

3.46e-0418633300ad1239b952119b3fd2e6af8f034cba3488f9c1
ToppCell5'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD48 GNA15 MAP3K5

3.57e-04188333ecbba19eebba21b986caa99de78ea4245fde3600
ToppCell5'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD48 GNA15 MAP3K5

3.57e-0418833372a1ee136d77c77e44793a512f60b5f7815a073a
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BACE1 KCNK12 EMILIN1

3.57e-04188333e079a3873cf442e98ff41a240c80b80995aace11
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD48 GNA15 IL9R

3.57e-04188333ab95a97db1a84bf3e53a4616a83ee81a6ce5ec12
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP MREG PLXNB1

3.63e-04189333783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCellwk_08-11-Hematologic_Lymphocytic-T_&_ILC-ILC2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CD48 GNA15 IL9R

3.63e-041893339c963f525ae765499b3e3229fead3aef018345ef
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERP MREG PLXNB1

3.63e-0418933388b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PERP MREG PLXNB1

3.68e-0419033347e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PERP MREG PLXNB1

3.68e-04190333261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCellMS-CD8-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

SYT15 PLCG1 MAP3K5

3.68e-041903338c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_Th17_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PERP MREG GNA15

3.68e-04190333693b223f6b94a46d935fbcb02d7a27340ce43154
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PERP GNA15 HSD17B2

3.80e-04192333612be3f861bd2f71a31c57f48c8b10930c3471ea
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PERP GNA15 HSD17B2

3.80e-04192333f627a3f43e2340c8ba502211940171f25c7ff436
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MREG KDM2B SPRED2

3.86e-04193333a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCellLAM-Lymphoid-T-cell|Lymphoid / Condition, Lineage and Cell class

PERP CD48 PLCG1

3.86e-041933330d9ceeb3c4d2bf5d13a29bf1b352cf2b70f3ed12
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MREG KDM2B SPRED2

3.86e-041933337426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSD17B2 EMILIN1 MAP3K5

3.92e-04194333ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSD17B2 EMILIN1 MAP3K5

3.92e-04194333240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GNA15 HTR6 ERO1A

3.97e-04195333d53585715c7f5827c4f5a6db11cb31857ee9d4f0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSD17B2 EMILIN1 MAP3K5

3.97e-04195333d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSD17B2 EMILIN1 MAP3K5

3.97e-04195333d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCelltumor_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

MREG KDM2B SPRED2

3.97e-0419533372a7c4beb880390b29f3c5d6dd9dbb082af50fe2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSD17B2 EMILIN1 MAP3K5

3.97e-0419533344d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MREG KDM2B EMILIN1

3.97e-0419533358b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCellfacs-Marrow-KLS-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK12 EMILIN1 ERO1A

4.03e-04196333c5adc95df9e1d1884a7988336e459a98c5a6769b
ToppCellBAL-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

MREG KDM2B SPRED2

4.03e-04196333c32b7b7e6a4781c19c30c6e32d5563f82355deb0
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MREG SYT15 FGF23

4.03e-04196333d5f9168001e60bafec17fe6c702e68f5528edc20
ToppCellfacs-Marrow-KLS-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK12 EMILIN1 ERO1A

4.03e-0419633381d1fd63397b2cf893607d828b61a926fa65185f
ToppCellBAL-Mild-cDC_10|Mild / Compartment, Disease Groups and Clusters

MREG KDM2B SPRED2

4.09e-04197333c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCelltumor_Lung-T/NK_cells-CD4+_Th|T/NK_cells / Location, Cell class and cell subclass

PERP CD48 GNA15

4.09e-041973330379d67beeba5864b5ffe5d282643204a112754f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSD17B2 EMILIN1 MAP3K5

4.09e-04197333b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSD17B2 EMILIN1 MAP3K5

4.09e-041973336d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BACE1 PRIMA1 MAP6D1

4.09e-0419733382b8e22317cad6d3786bd70d91107007c0ccd7cd
DrugMoxalactam disodium salt [64953-12-4]; Down 200; 7uM; MCF7; HT_HG-U133A

GNA15 KCNK12 PLCG1 SPRED2 CEP72

7.87e-061983255609_DN
Diseaseschizophrenia (implicated_via_orthology)

BACE1 MAP6

2.33e-0368312DOID:5419 (implicated_via_orthology)
DiseaseAlzheimer's disease (is_implicated_in)

BACE1 HTR6

8.48e-03132312DOID:10652 (is_implicated_in)
Diseasecolorectal cancer (is_marker_for)

PLCG1 ADGRB1

1.18e-02157312DOID:9256 (is_marker_for)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

BACE1 MAP3K5

1.18e-02157312DOID:224 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RSFERSWMPCARCCR

FAM246C

141

P0DSO1
LPLCLMVCQWRCLRC

BACE1

471

P56817
RGLCLLWTAFDVMCC

HTR6

96

P50406
CQMLCRWLDACLAGS

ADGRB1

186

O14514
RRSSCRGCCLEKMPW

CEP72

256

Q9P209
LCICMRVCRTWSRWC

FBXL19

441

Q6PCT2
MAWPCITRACCIARF

MAP6

1

Q96JE9
VCLAACRAMWGLAAR

CELF2-AS1

71

Q8N7Q2
WCCGRNARMSACLAL

METTL25

446

Q8N6Q8
NLWCSGRVCCEGMLI

CCDC47

206

Q96A33
WCVLLGRCSRRSECS

PLXNB1

501

O43157
LNWMLRKLSCRCCAR

KCNK12

306

Q9HB15
MIRCGLACERCRWIL

PERP

1

Q96FX8
MARSLTWRCCPWCLT

GNA15

1

P30679
TCCAISLWLRGLRMC

PROK1

36

P58294
DLCVCMRVCRTWNRW

KDM2B

1081

Q8NHM5
GCFRELCALCWMLHV

CPLANE1

1271

Q9H799
MLGARLRLWVCALCS

FGF23

1

Q9GZV9
LRLWVCALCSVCSMS

FGF23

6

Q9GZV9
MRPRCCILALVCWIT

IGFL3

1

Q6UXB1
SRIMDCVGCFKCRLW

ERO1A

386

Q96HE7
MAWPCISRLCCLARR

MAP6D1

1

Q9H9H5
MWSARLLTCRCGVPA

CRIPAK

246

Q8N1N5
MWSARLLTCRCGVPA

CRIPAK

266

Q8N1N5
MAPRTLWSCYLCCLL

EMILIN1

1

Q9Y6C2
MCSRGWDSCLALELL

CD48

1

P09326
SWMVCLAGLCAVCLL

HSD17B2

36

P37059
CLRLRGGMLCTLWKA

MAP3K5

1351

Q99683
LIGASCCLWRRFCAT

SYT15

21

Q9BQS2
SPIRCCWLRLRCLAA

TMEM265

21

A0A087WTH1
CWLRLRCLAATSIIC

TMEM265

26

A0A087WTH1
MGLRDWLRTVCCCCG

MREG

1

Q8N565
MLLRDLVLRRGCCWS

PRIMA1

1

Q86XR5
DMGTWLLACICICTC

IL9R

21

Q01113
GLREMLKARLWCSCS

SLC26A1

26

Q9H2B4
CLRMGCRCIELDCWD

PLCG1

356

P19174
DSVRTCIRRVSCMWC

SPRED2

331

Q7Z698
CIRRVSCMWCADSML

SPRED2

336

Q7Z698
MGSWTLCCVSLCILV

TRBV12-4

1

A0A0B4J2E0