Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCC3 ABCC4 ABCB7 MYO9B RSF1 MCM3 ATP9B ATP8B1 KIF2B RAB40AL SEPTIN1 KIF28P DDX60L ABCC2 DNM1 DNAH6 AGAP2 KIF2C DIRAS1 ABCC5 CHD7 MORC4 SAR1A RGS7 RAB18 GTPBP2 SAR1B HSPA14 DIRAS2

6.47e-0977521729GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

ABCC3 ABCC4 ABCB7 MYO9B RSF1 MCM3 ATP9B ATP8B1 KIF2B RAB40AL SEPTIN1 KIF28P DDX60L ABCC2 DNM1 DNAH6 AGAP2 KIF2C DIRAS1 ABCC5 CHD7 MORC4 SAR1A RGS7 RAB18 GTPBP2 SAR1B HSPA14 DIRAS2

3.69e-0883921729GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ABCC3 ABCC4 ABCB7 MYO9B RSF1 MCM3 ATP9B ATP8B1 KIF2B RAB40AL SEPTIN1 KIF28P DDX60L ABCC2 DNM1 DNAH6 AGAP2 KIF2C DIRAS1 ABCC5 CHD7 MORC4 SAR1A RGS7 RAB18 GTPBP2 SAR1B HSPA14 DIRAS2

3.78e-0884021729GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ABCC3 ABCC4 ABCB7 MYO9B RSF1 MCM3 ATP9B ATP8B1 KIF2B RAB40AL SEPTIN1 KIF28P DDX60L ABCC2 DNM1 DNAH6 AGAP2 KIF2C DIRAS1 ABCC5 CHD7 MORC4 SAR1A RGS7 RAB18 GTPBP2 SAR1B HSPA14 DIRAS2

3.78e-0884021729GO:0016818
GeneOntologyMolecularFunctionATP-dependent activity

ABCC3 ABCC4 ABCB7 MYO9B ZGRF1 RSF1 MCM3 ATP9B ATP8B1 KIF2B KIF28P DDX60L ABCC2 DNAH6 SLC27A4 KIF2C ABCC5 CHD7 MORC4 MYH14 HSPA14 HELLS

1.02e-0661421722GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC3 ABCC4 ABCB7 MYO9B RSF1 MCM3 ATP9B ATP8B1 KIF2B KIF28P DDX60L ABCC2 DNAH6 KIF2C ABCC5 CHD7 MORC4 HSPA14

1.69e-0644121718GO:0016887
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC3 ABCC4 ABCC2 ABCC5

2.71e-06102174GO:0043225
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

ARHGAP32 STARD8 MYCBP2 DOCK11 MYO9B OBSCN ARHGEF11 PGAM5 RGL1 NF1 SRGAP3 AGAP2 LARS1 MON1A RGS7 ARHGEF10L ARAP3 SBF2

1.16e-0550721718GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

ARHGAP32 STARD8 MYCBP2 DOCK11 MYO9B OBSCN ARHGEF11 PGAM5 RGL1 NF1 SRGAP3 AGAP2 LARS1 MON1A RGS7 ARHGEF10L ARAP3 SBF2

1.16e-0550721718GO:0030695
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC3 ABCC4 ABCC2 ABCC5

1.69e-05152174GO:0008559
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP32 STARD8 MYO9B ARHGEF11 PGAM5 NF1 SRGAP3 AGAP2 LARS1 RGS7 ARHGEF10L ARAP3

5.77e-0527921712GO:0005096
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC3 ABCC4 ABCC2

6.81e-0582173GO:0015431
GeneOntologyMolecularFunctionamino acid sensor activity

SAR1A SAR1B

1.18e-0422172GO:0140785
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

1.87e-04492175GO:0140359
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

ABCC4 SLC25A23 SLC25A17 ABCC5

2.60e-04292174GO:0015216
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

ABCC4 SLC25A23 SLC25A17 ABCC5

4.34e-04332174GO:0015215
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC3 ABCC4 ABCC2 ABCC5

4.87e-04342174GO:0042910
GeneOntologyMolecularFunctioncaspase binding

MAGEA10 RIOK3 NLRC4

6.39e-04162173GO:0089720
GeneOntologyMolecularFunctionABC-type bile acid transporter activity

ABCC3 ABCC4

6.95e-0442172GO:0015432
GeneOntologyMolecularFunctionATPase-coupled organic acid transmembrane transporter activity

ABCC3 ABCC4

6.95e-0442172GO:0033283
GeneOntologyMolecularFunctionATPase-coupled monocarboxylic acid transmembrane transporter activity

ABCC3 ABCC4

6.95e-0442172GO:0033285
GeneOntologyMolecularFunctionATPase-coupled carboxylic acid transmembrane transporter activity

ABCC3 ABCC4

6.95e-0442172GO:0033284
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

ABCC4 SLC25A23 SLC25A17 ABCC5

8.28e-04392174GO:0015605
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SUN2 SYNE1

1.15e-0352172GO:0140444
GeneOntologyMolecularFunctionlipid binding

ARHGAP32 MINAR2 STARD8 FRMPD4 TEX2 SPTBN1 OBSCN ATP8B1 HNF4A ITPR2 FZD7 RBP7 NF1 COMMD1 UGT2B15 UGT2B17 PLA2G2A DNM1 VEPH1 ARAP3 SBF2 SMO

1.16e-0398821722GO:0008289
GeneOntologyMolecularFunctionphosphatase activity

CDC14C ACP6 DUSP28 INPP5B LRRIQ4 PGAM5 TIGAR MTMR8 CDC14B MTMR7

1.23e-0328721710GO:0016791
GeneOntologyMolecularFunctionGTPase activity

RAB40AL SEPTIN1 DNM1 AGAP2 DIRAS1 SAR1A RGS7 RAB18 GTPBP2 SAR1B DIRAS2

1.32e-0334121711GO:0003924
GeneOntologyMolecularFunctionphosphatidylinositol phosphate binding

ARHGAP32 FRMPD4 OBSCN FZD7 COMMD1 DNM1 VEPH1 ARAP3

1.54e-031992178GO:1901981
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

1.71e-0362172GO:0034647
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO9B KIF2B KIF28P DNAH6 KIF2C MYH14

1.84e-031182176GO:0003774
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

OBSCN COMMD1 DNM1 ARAP3

1.96e-03492174GO:0005547
GeneOntologyMolecularFunctionenzyme activator activity

ARHGAP32 STARD8 MYO9B ARHGEF11 PGAM5 NLRC4 NF1 SRGAP3 AGAP2 LARS1 TOPBP1 CASP9 RGS7 ARHGEF10L ARAP3 FAM20A

2.25e-0365621716GO:0008047
GeneOntologyBiologicalProcessxenobiotic transmembrane transport

ABCC3 ABCC4 ATP8B1 ABCC2 ABCC5

1.24e-06192165GO:0006855
GeneOntologyBiologicalProcessleukotriene transport

ABCC3 ABCC4 ABCC2

3.84e-0572163GO:0071716
GeneOntologyBiologicalProcesspurine ribonucleotide transport

ABCC4 SLC25A23 SLC25A17 ABCC5 LRRC8D

5.87e-05402165GO:0015868
GeneOntologyBiologicalProcessadenine nucleotide transport

ABCC4 SLC25A23 SLC25A17 ABCC5 LRRC8D

7.46e-05422165GO:0051503
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

CDC14C ABCC4 NCKAP1 DOCK11 DZIP1L ITGA6 ATP8B1 HNF4A CFAP410 BBOF1 RPGRIP1 CCDC146 CEP162 SYNE1 CDC14B FMNL3 NEURL1 MPHOSPH9 CCDC65

8.60e-0567021619GO:0120031
GeneOntologyBiologicalProcesspurine nucleotide transport

ABCC4 SLC25A23 SLC25A17 ABCC5 LRRC8D

9.37e-05442165GO:0015865
GeneOntologyBiologicalProcesscAMP transport

ABCC4 ABCC5

1.09e-0422162GO:0070730
GeneOntologyBiologicalProcesscell projection assembly

CDC14C ABCC4 NCKAP1 DOCK11 DZIP1L ITGA6 ATP8B1 HNF4A CFAP410 BBOF1 RPGRIP1 CCDC146 CEP162 SYNE1 CDC14B FMNL3 NEURL1 MPHOSPH9 CCDC65

1.15e-0468521619GO:0030031
GeneOntologyBiologicalProcessxenobiotic metabolic process

ABCC3 ABCC4 HNF4A AHR UGT2B15 UGT2B17 ABCC2 ABCC5

1.22e-041412168GO:0006805
DomainP-loop_NTPase

ABCC3 ABCC4 ABCB7 MYO9B ZGRF1 MCM3 NLRC4 KIF2B RAB40AL SEPTIN1 DDX60L ABCC2 DNM1 DNAH6 AGAP2 KIF2C DIRAS1 ABCC5 CHD7 SAR1A RAB18 GTPBP2 MYH14 SAR1B DIRAS2 HELLS

2.88e-0684820826IPR027417
DomainABC_membrane

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

5.84e-06242085PF00664
DomainABC_TM1F

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

1.30e-05282085PS50929
DomainABC1_TM_dom

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

1.30e-05282085IPR011527
Domain-

ABCC3 ABCC4 ABCB7 ZGRF1 MCM3 NLRC4 RAB40AL SEPTIN1 DDX60L ABCC2 DNM1 DNAH6 AGAP2 DIRAS1 ABCC5 CHD7 SAR1A RAB18 GTPBP2 SAR1B DIRAS2 HELLS

3.19e-05746208223.40.50.300
DomainRho_GTPase_activation_prot

ARHGAP32 STARD8 MYO9B INPP5B NF1 SRGAP3 ARAP3

5.68e-05882087IPR008936
DomainRhoGAP

ARHGAP32 STARD8 MYO9B INPP5B SRGAP3 ARAP3

6.49e-05622086SM00324
DomainRhoGAP

ARHGAP32 STARD8 MYO9B INPP5B SRGAP3 ARAP3

7.11e-05632086PF00620
DomainRhoGAP_dom

ARHGAP32 STARD8 MYO9B INPP5B SRGAP3 ARAP3

7.77e-05642086IPR000198
DomainRHOGAP

ARHGAP32 STARD8 MYO9B INPP5B SRGAP3 ARAP3

7.77e-05642086PS50238
Domain-

ARHGAP32 STARD8 MYO9B INPP5B SRGAP3 ARAP3

7.77e-056420861.10.555.10
DomainABC_transporter_CS

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

9.93e-05422085IPR017871
DomainSAR1

SAR1A SAR1B

1.23e-0422082PS51422
DomainSmall_GTPase_SAR1

SAR1A SAR1B

1.23e-0422082IPR006687
DomainABC_tran

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

1.89e-04482085PF00005
DomainABC_TRANSPORTER_2

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

1.89e-04482085PS50893
DomainABC_TRANSPORTER_1

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

2.09e-04492085PS00211
DomainABC_transporter-like

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

2.30e-04502085IPR003439
DomainPH

DOCK11 TEX2 SPTBN1 OBSCN ARHGEF11 PLEKHH1 DNM1 AGAP2 VEPH1 ARAP3 SBF2

2.97e-0427820811SM00233
DomainPH_dom-like

FRMPD4 DOCK11 SPTBN1 OBSCN ARHGEF11 PLEKHH1 DNM1 AGAP2 VEPH1 MTMR8 ARHGEF10L MTMR7 ARAP3 SBF2

3.14e-0442620814IPR011993
DomainPH_domain

DOCK11 TEX2 SPTBN1 OBSCN ARHGEF11 PLEKHH1 DNM1 AGAP2 VEPH1 ARAP3 SBF2

3.15e-0428020811IPR001849
DomainMyotubularin-like_Pase_dom

MTMR8 MTMR7 SBF2

4.53e-04142083IPR010569
DomainPPASE_MYOTUBULARIN

MTMR8 MTMR7 SBF2

4.53e-04142083PS51339
DomainMyotubularin_fam

MTMR8 MTMR7 SBF2

4.53e-04142083IPR030564
DomainMyotub-related

MTMR8 MTMR7 SBF2

4.53e-04142083PF06602
Domain-

DOCK11 SPTBN1 OBSCN ARHGEF11 PLEKHH1 DNM1 AGAP2 VEPH1 MTMR8 ARHGEF10L MTMR7 ARAP3 SBF2

4.60e-04391208132.30.29.30
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

7.30e-0442082IPR013637
DomainPLU-1

KDM5C KDM5D

7.30e-0442082PF08429
DomainMultidrug-R_assoc

ABCC3 ABCC2

7.30e-0442082IPR005292
DomainPH

DOCK11 SPTBN1 OBSCN PLEKHH1 DNM1 AGAP2 VEPH1 ARAP3 SBF2

1.10e-032292089PF00169
DomainPyr_redox_2

FOXRED2 PCYOX1 GSR

1.16e-03192083PF07992
DomainAAA

ABCC3 ABCC4 ABCB7 MCM3 ABCC2 DNAH6 ABCC5

1.17e-031442087SM00382
DomainAAA+_ATPase

ABCC3 ABCC4 ABCB7 MCM3 ABCC2 DNAH6 ABCC5

1.17e-031442087IPR003593
DomainPH_DOMAIN

DOCK11 SPTBN1 OBSCN ARHGEF11 PLEKHH1 DNM1 AGAP2 VEPH1 ARAP3 SBF2

1.18e-0327920810PS50003
Domainzf-C5HC2

KDM5C KDM5D

1.21e-0352082PF02928
DomainCyt_P450_CYP7A1-type

CYP8B1 PTGIS

1.21e-0352082IPR024204
DomainZnf_C5HC2

KDM5C KDM5D

1.21e-0352082IPR004198
Domain-

ACP6 PGAM5 TIGAR

1.35e-032020833.40.50.1240
DomainHis_PPase_superfam

ACP6 PGAM5 TIGAR

1.35e-03202083IPR029033
DomainARM-type_fold

SMG1 GPRASP1 DOCK11 CLHC1 ITPR2 NF1 PUM3 VEPH1 RANBP6 FMNL3 THADA

1.52e-0333920811IPR016024
PathwayREACTOME_PARACETAMOL_ADME

ABCC3 ABCC4 UGT2B15 UGT2B17 ABCC2 ABCC5

5.00e-06391626MM15695
PathwayWP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT

ABCC3 ABCC4 CYP8B1 ATP8B1 ABCC2

1.79e-05291625M45551
PathwayREACTOME_PARACETAMOL_ADME

ABCC3 ABCC4 UGT2B15 ABCC2 ABCC5

1.79e-05291625M45015
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARHGAP32 STARD8 MYO9B TEX2 OBSCN ARHGEF11 ARHGEF10L FMNL3 ARAP3

3.79e-051421629MM15576
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARHGAP32 STARD8 MYO9B TEX2 OBSCN ARHGEF11 ARHGEF10L FMNL3 ARAP3

5.53e-051491629M41805
PathwayWP_CHOLESTASIS

ABCC3 ABCC4 ATP8B1 ABCC2

5.69e-05191624M45520
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARHGAP32 STARD8 DOCK11 MYO9B ARHGEF11 SRGAP3 ARAP3

1.03e-04941627MM15598
PathwayKEGG_ABC_TRANSPORTERS

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

1.42e-04441625M11911
PathwayPID_RHOA_REG_PATHWAY

MYO9B OBSCN ARHGEF11 ARHGEF10L ARAP3

1.77e-04461625M68
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CTTNBP2 TEX2 DNAH6 SYNE1 VEPH1 THADA SBF2 CNTNAP4 ZFHX2

1.82e-08102219911214970
Pubmed

Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.

ABCC3 ABCC4 ABCC2 ABCC5

5.28e-087219420922799
Pubmed

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

ABCC3 ABCC4 ABCC2 ABCC5

1.05e-078219415802388
Pubmed

Expression of testicular germ cell genes identified by differential display analysis.

ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

1.05e-078219412634303
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGAP32 CTTNBP2 STARD8 CEP68 RGL1 PARP4 SUN2 ZNF347 PUM3 PCYOX1 DMXL2 THADA LMBR1L SBF2 CNTNAP4 SPIDR

1.14e-074932191615368895
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 ABCC3 ARHGAP32 WDR64 RSF1 PLEKHH1 PARP4 NF1 WDR17 KDM6A WEE1 ZDBF2 CHD7 MED1 MORC4 SAR1A ALX1 HELLS

1.47e-076382191831182584
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

MTA2 ABCC3 ABCC4 ABCB7 MYCBP2 ITGA6 GTF3C3 ITPR2 STIM1 CSDE1 FOXRED2 NF1 SUN2 PRPF19 CFAP410 PCYOX1 KIF2C RANBP6 CPD NCSTN LRRC8D GSR THADA UGGT2 EXOSC7

1.88e-0712012192535696571
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCC3 ABCC4 ABCB7 ABCC2 ABCC5

2.28e-072221958894702
Pubmed

Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.

ABCC3 ABCC4 ABCC2

2.46e-073219317273943
Pubmed

Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.

ABCC3 ABCC4 ABCC2

2.46e-073219325952649
Pubmed

Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers.

ABCC3 ABCC4 ABCC2

2.46e-073219319480556
Pubmed

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

ABCC3 ABCC4 ABCC5

2.46e-07321939270026
Pubmed

ATP-binding cassette C transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells.

ABCC3 ABCC4 ABCC5

2.46e-073219319077464
Pubmed

Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides.

ABCC3 ABCC4 ABCC2

2.46e-073219317485564
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ABCB7 MYCBP2 TRPM7 TEX2 SPTBN1 PGAM5 GTF3C3 ITPR2 STIM1 R3HCC1L SUN2 ASCC2 SCO1 PRPF19 ELOC TIGAR DMXL2 SYNE1 SMPD4 CPD OGDH GSR THADA NUP155 UGGT2 AKAP11 HSPA14 HELLS

2.54e-0714872192833957083
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SMG1 TEX2 KDM5C KMT2C CEP162 LARS1 TOPBP1 SMPD4 ICE1 NCSTN ARHGEF10L FMNL3 TRMT6 NUP155 AKAP11 EXOSC7

2.95e-075292191614621295
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

TRPM7 TEX2 ITGA6 ITPR2 STIM1 SUN2 SLC27A4 SMPD4 CPD LRRC8D SAR1A NUP155 SAR1B UGGT2 STX10

3.37e-074682191531056421
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ABCC4 TRPM7 TEX2 ITGA6 ITPR2 STIM1 SUN2 SLC27A4 DMXL2 CPD MON1A NUP155 SAR1B AKAP11 STX10

8.54e-075042191534432599
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SMG1 MYCBP2 DOCK11 MCM3 GTF3C3 ITPR2 NF1 ASCC2 PUM3 WEE1 MED1 NUP155 MYH14 EXOSC7

9.14e-074402191434244565
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPRASP1 ARHGAP32 CTTNBP2 NCKAP1 MYCBP2 DOCK11 SPTBN1 MCM3 ARHGEF11 PGAM5 NF1 SRGAP3 DNM1 AGAP2 KIF2C DMXL2 SYNE1 DGKZ CHD7 GRIK5 WDR47

9.14e-079632192128671696
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DUSP28 ARHGAP32 MYCBP2 SPTBN1 ITGA6 ITPR2 STIM1 PHKA1 SUN2 PRPF19 KDM6A CEP162 MTMR8 SMPD4 CPD CDC14B GTF2E1 MTMR7 NUP155 SBF2 MPHOSPH9 HELLS

9.46e-0710492192227880917
Pubmed

Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy.

ABCC4 ABCC2 ABCC5

9.81e-074219318690847
Pubmed

Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells.

ABCC3 ABCC2 ABCC5

9.81e-074219319956884
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM5C KDM5D KDM6A

9.81e-074219332732223
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SMG1 MYCBP2 CEP68 KMT2C SALL2 SRGAP3 DMXL2 SYNE1 CHD7 AKAP11

1.84e-062252191012168954
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

ARHGAP32 NCKAP1 SPTBN1 NF1 SRGAP3 DNM1 AGAP2 DMXL2 SYNE1 DGKZ AKAP11

1.93e-062812191128706196
Pubmed

Efflux protein expression in human stem cell-derived retinal pigment epithelial cells.

ABCC3 ABCC4 ABCC5

2.44e-065219322272278
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

TRPM7 INPP5B MCM3 GTF3C3 TASOR2 STIM1 TCF12 CCDC146 CEP162 ABCC5 SAR1A THADA GTPBP2 NUP155 SAR1B MPHOSPH9 DEPDC7 HELLS

2.47e-067772191835844135
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NCKAP1 DOCK11 KDM5C SPTBN1 OBSCN ARHGEF11 KMT2C KIF2B SEPTIN1 ASCC2 KIF2C CASP9 MON1A HELLS

3.76e-064972191436774506
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

ARHGAP32 CTTNBP2 NCKAP1 SPTBN1 DNM1 AGAP2 DMXL2 SYNE1 DGKZ GRIK5

4.87e-062512191027507650
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

MTA2 SMG1 ABCB7 SPTBN1 MCM3 PGAM5 ITPR2 CSDE1 COMMD1 SUN2 ASCC2 PRPF19 PUM3 DDX60L SLC27A4 LARS1 RANBP6 SMPD4 OGDH CCNE1 RAB18 THADA NUP155 STX10 HELLS

4.92e-0614402192530833792
Pubmed

The sperm-associated antigen 6 interactome and its role in spermatogenesis.

SMG1 MYCBP2 CAGE1 DNM1 WDR17 PCYOX1 DGKZ ANKEF1 CCDC65

5.27e-06199219931146259
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MTA2 NCKAP1 MYCBP2 MYO9B SPTBN1 RSF1 MCM3 RIOK3 PGAM5 GTF3C3 CSDE1 NF1 PRPF19 PUM3 DDX60L SLC27A4 KIF2C LARS1 ADNP2 CHD7 WDR47 ARAP3 NUP155 MYH14

5.39e-0613532192429467282
Pubmed

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.

ATP8B1 FZD7 RGL1 KIAA2012 PKD1L3

5.89e-0641219518951430
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MTA2 ABCC3 MYCBP2 MYO9B OBSCN ZNF236 ARHGEF11 ITPR2 FZD7 KMT2C DIRAS1 MTMR8 ICE1 CDC14B ARHGEF10L THAP11 CCNE1 THADA OVOL1 ARAP3 SBF2

7.72e-0611052192135748872
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

MTA2 RSF1 KDM5D PGAM5 TASOR2 SALL2 PRPF19 ELOC TCF12 ADNP2 CHD7 MED1

1.32e-054112191235182466
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 DZIP1L SPTBN1 RSF1 CAGE1 PGAM5 TASOR2 PRPF19 ABCC2 KIAA2012 DNAH6 SLC27A4 AGAP2 BBOF1 RPGRIP1 SYNE1 KHDRBS2 ABCC5 CFAP210 OGDH GSR MYH14 UGGT2 PABPC1L

1.54e-0514422192435575683
Pubmed

Defining the membrane proteome of NK cells.

MTA2 ABCC4 MYCBP2 MYO9B MCM3 ITPR2 PARP4 NF1 PRPF19 SLC25A17 SLC27A4 AGAP2 KIF2C CPD NCSTN MED1 LRRC8D NUP155 MYH14 MPHOSPH9 HSPA14

1.76e-0511682192119946888
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SMG1 CTTNBP2 MYCBP2 SPTBN1 OBSCN RIOK3 PARP4 PUM3 DMXL2 TCF12 MYOT SYNE1 MYH14

1.83e-054972191323414517
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

ABCC3 ABCC4 ABCC2 SLC27A4 ABCC5

1.93e-0552219526590417
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DOCK11 OBSCN OIP5 ANKRD20A3P PGAM5 ITPR2 KMT2C PARP4 R3HCC1L SRGAP3 AHR MAGEE2 ICE1 GRIK5 TRMT6 FBXO43

1.98e-057362191629676528
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

SPTBN1 ITGA6 CLHC1 ITPR2 STIM1 CSDE1 SALL2 KIF2B SUN2 ELOC TCF12 THADA MYH14

2.08e-055032191336217030
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MYO9B ZGRF1 KDM5C MCM3 RIOK3 PGAM5 SALL2 KIF2C WEE1 TOPBP1 ZDBF2 CHD7 MORC4 GSR

2.47e-055882191438580884
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ABCB7 MYCBP2 STIM1 CEP68 FOXRED2 COMMD1 SUN2 ASCC2 PUM3 SLC27A4 PCYOX1 ELOC TCF12 RAB18 MYH14 UGGT2

2.64e-057542191633060197
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MTA2 MYCBP2 MYO9B GTF3C3 CSDE1 PRPF19 PUM3 KIF2C LARS1 TOPBP1 MED1 OGDH THAP11 NUP155 EXOSC7 HSPA14

2.86e-057592191635915203
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ABCB7 NCKAP1 MYO9B KDM5C GTF3C3 SALL2 ANKRD20A1 KIF2C TCF12 PARG LARS1 SMPD4 WDR47 ZFHX4 SPIDR HSPA14 HELLS

3.44e-058572191725609649
Pubmed

Maternal bile acid transporter deficiency promotes neonatal demise.

ABCC3 ABCC4 HNF4A PGAM5 ABCC2

3.59e-0559219526416771
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARHGAP32 NCKAP1 MYCBP2 TRPM7 DOCK11 TEX2 SPTBN1 STIM1 NF1 KIF2C WEE1 CEP162 FSD1 NEURL1 AKAP11 MPHOSPH9 MAP3K2

3.65e-058612191736931259
Pubmed

Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.

ABCC3 ABCC4 ABCC2 GSR

3.69e-0530219420200426
Pubmed

Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos.

CDC14C CDC14B

3.95e-052219219923902
Pubmed

The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway.

CDC14C CDC14B

3.95e-052219221502810
Pubmed

Targeting Aryl Hydrocarbon Receptor Signaling Enhances Type I Interferon-Independent Resistance to Herpes Simplex Virus.

AHR IFNB1

3.95e-052219234668726
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

3.95e-052219232660355
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

3.95e-052219210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

3.95e-052219216416087
Pubmed

Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein.

CDC14C CDC14B

3.95e-052219218547142
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

3.95e-05221921909870
Pubmed

Immunohistochemical Assessment of the Expression of Biliary Transportation Proteins MRP2 and MRP3 in Hepatocellular Carcinoma and in Cholangiocarcinoma.

ABCC3 ABCC2

3.95e-052219229464551
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

3.95e-052219224121496
Pubmed

Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo.

SAR1A SAR1B

3.95e-052219238687799
Pubmed

Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis.

AHR OVOL1

3.95e-052219228703805
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

3.95e-052219224267955
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

3.95e-052219232081420
Pubmed

Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.

UGT2B15 UGT2B17

3.95e-052219222170718
Pubmed

Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.

ABCC3 ABCC2

3.95e-052219221841039
Pubmed

Silencing of mammalian Sar1 isoforms reveals COPII-independent protein sorting and transport.

SAR1A SAR1B

3.95e-052219223433038
Pubmed

The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis.

SAR1A SAR1B

3.95e-052219224338480
Pubmed

Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.

UGT2B15 UGT2B17

3.95e-05221923105095
Pubmed

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.

UGT2B15 UGT2B17

3.95e-052219217848572
Pubmed

Modulation of membrane rigidity by the human vesicle trafficking proteins Sar1A and Sar1B.

SAR1A SAR1B

3.95e-052219222974979
Pubmed

MEKK2 mediates aberrant ERK activation in neurofibromatosis type I.

NF1 MAP3K2

3.95e-052219233177525
Pubmed

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

UGT2B15 UGT2B17

3.95e-052219227496708
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

3.95e-05221927524912
Pubmed

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

UGT2B15 UGT2B17

3.95e-052219217698910
Pubmed

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5.

ABCC4 ABCC5

3.95e-052219212695538
Pubmed

ALX1 induces snail expression to promote epithelial-to-mesenchymal transition and invasion of ovarian cancer cells.

ALX1 SNAI1

3.95e-052219223288509
Pubmed

Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.

ABCC3 ABCC2

3.95e-052219212704183
Pubmed

Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver.

ABCC3 ITPR2

3.95e-052219220578149
Pubmed

Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy.

ABCC4 ABCC2

3.95e-052219217083032
Pubmed

Re: Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.

ABCC3 ABCC5

3.95e-052219210340910
Pubmed

Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.

ABCC3 ABCC2

3.95e-052219225788542
Pubmed

AhR ligand aminoflavone suppresses α6-integrin-Src-Akt signaling to attenuate tamoxifen resistance in breast cancer cells.

ITGA6 AHR

3.95e-052219230076704
Pubmed

The X-linked histone demethylases KDM5C and KDM6A as regulators of T cell-driven autoimmunity in the central nervous system.

KDM5C KDM6A

3.95e-052219237657612
Pubmed

Oral availability of cefadroxil depends on ABCC3 and ABCC4.

ABCC3 ABCC4

3.95e-052219222166395
Pubmed

Dependence of multidrug resistance protein-mediated cyclic nucleotide efflux on the background sodium conductance.

ABCC4 ABCC5

3.95e-052219219903828
Pubmed

Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma.

ABCC3 ABCC2

3.95e-052219211745434
Pubmed

Genome stability is ensured by temporal control of kinetochore-microtubule dynamics.

KIF2B KIF2C

3.95e-052219219060894
Pubmed

Influence of ABCC2 and ABCC4 polymorphisms on tenofovir plasma concentrations in Thai HIV-infected patients.

ABCC4 ABCC2

3.95e-052219225801567
Pubmed

Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.

UGT2B15 UGT2B17

3.95e-05221923117546
Pubmed

Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.

ABCC3 ABCC2

3.95e-052219230959153
Pubmed

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

ABCC3 ABCC2

3.95e-052219219088030
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

3.95e-05221929060413
Pubmed

Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells.

ABCC4 ABCC5

3.95e-052219212637526
Pubmed

Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma.

ABCC3 ABCC5

3.95e-052219215688370
Pubmed

AhR ligand Aminoflavone inhibits α6-integrin expression and breast cancer sphere-initiating capacity.

ITGA6 AHR

3.95e-052219226996297
Pubmed

Polymorphisms in the methotrexate transport pathway: a new tool for MTX plasma level prediction in pediatric acute lymphoblastic leukemia.

ABCC4 ABCC2

3.95e-052219223222202
Pubmed

Molecular analysis of SAR1-related cDNAs from a mouse pituitary cell line.

SAR1A SAR1B

3.95e-05221928262187
Pubmed

Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.

UGT2B15 UGT2B17

3.95e-052219228228532
Pubmed

SAR1B senses leucine levels to regulate mTORC1 signalling.

SAR1A SAR1B

3.95e-052219234290409
Pubmed

An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs.

HNF4A SNAI1

3.95e-052219222139130
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC4 ABCC2 ABCC5

3.41e-06131544807
GeneFamilyCytochrome P450 family 8

CYP8B1 PTGIS

7.21e-05215421006
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ADNP2 ZFHX4 ZFHX2

2.56e-04151543529
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR8 MTMR7 SBF2

2.56e-04151543903
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 SPTBN1 PLEKHH1 DNM1 AGAP2 VEPH1 ARAP3 SBF2

3.91e-042061548682
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5C KDM5D KDM6A

1.08e-03241543485
GeneFamilyAnkyrin repeat domain containing

CTTNBP2 ANKRD20A2P ANKRD20A3P ANKRD20A4P ANKRD20A1 AGAP2 ARAP3 ANKEF1

1.12e-032421548403
GeneFamilyPhosphoinositide phosphatases

INPP5B MTMR8 MTMR7

2.51e-033215431079
GeneFamilyZinc fingers C2H2-type|SNAG transcriptional repressors

OVOL1 SNAI1

3.10e-031015421259
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD7 SMO

3.77e-03111542286
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_GHRL_POS_NE_PRECURSOR_CELL

ARHGAP32 DOCK11 TEX2 ARHGEF11 PLEKHH1 SRGAP3 DGKZ GRIK5 RGS7 ARHGEF10L MTMR7 NEURL1 ZFHX2 DIRAS2

1.36e-0542921514M45694
CoexpressionWHITFIELD_CELL_CYCLE_S

LYRM7 MYCBP2 ABCC2 DMXL2 ABCC5 DEPDC7 MAP3K2 HELLS

3.49e-051502158M2075
CoexpressionMARTIN_NFKB_TARGETS_UP

CDC14C INHBB C1S FSD1 CDC14B

3.70e-05462155MM552
CoexpressionGSE20727_CTRL_VS_H2O2_TREATED_DC_DN

MYCBP2 DOCK11 SUN2 WDR17 KHDRBS2 CHD7 FMNL3 THADA AKAP11

3.70e-051962159M9243
CoexpressionGSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN

GPRASP1 ITGA6 AHR DDX60L PCYOX1 ABCC5 GSR RAB18 SBF2

4.00e-051982159M3325
CoexpressionGSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP

SMG1 DOCK11 ZNF844 KHDRBS2 LARS1 ABCC5 CHD7 FMNL3 THADA

4.16e-051992159M9238
CoexpressionGSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP

ABCB7 SPTBN1 CEP68 SUN2 PRPF19 ADNP2 RANBP6 THAP11 MPHOSPH9

4.33e-052002159M4497
CoexpressionGSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_DN

NCKAP1 MCM3 PUM3 TIGAR TCF12 WEE1 TAF1A ELL2 HSPA14

4.33e-052002159M4410
CoexpressionPUJANA_CHEK2_PCC_NETWORK

ABCB7 OIP5 MCM3 NF1 PRPF19 PUM3 KIF2C ELOC WEE1 PARG KHDRBS2 TOPBP1 ADNP2 SMPD4 SAR1A GSR GTF2E1 MPHOSPH9

6.15e-0576121518M11961
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DZIP1L ALDH3B1 KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

4.87e-071922199be592e661367affced9ebe80849b466e6adb3a34
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DZIP1L ALDH3B1 KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

5.08e-0719321990b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTA2 SMG1 STIM1 CSDE1 KMT2C SUN2 TCF12 ABCC5 DGKZ

5.31e-071942199f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTA2 SMG1 STIM1 CSDE1 KMT2C SUN2 TCF12 ABCC5 DGKZ

5.31e-071942199cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTA2 SMG1 STIM1 CSDE1 KMT2C SUN2 TCF12 ABCC5 DGKZ

5.31e-07194219966c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

STARD8 DZIP1L ARHGEF11 NLRC4 CUEDC1 RGL1 DMXL2 ARHGEF10L FAM20A

6.57e-071992199facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

STARD8 DZIP1L ARHGEF11 NLRC4 CUEDC1 RGL1 DMXL2 ARHGEF10L FAM20A

6.57e-071992199dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ITGA6 ITPR2 STIM1 ABCC5 LRRC9 NEURL1 EXOSC7

2.46e-0617421985f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ITGA6 ITPR2 STIM1 ABCC5 LRRC9 NEURL1 EXOSC7

2.56e-06175219877c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

ABCC4 CTTNBP2 ITGA6 ITPR2 FZD7 ABCC5 NEURL1 EXOSC7

3.57e-0618321985c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

MCM3 NALCN KIAA2012 KIF2C WEE1 CCNE1 CXCR1 HELLS

4.53e-061892198946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO9B ATP9B KMT2C KDM6A TCF12 ELL2 SBF2 SPIDR

5.29e-061932198779276e775cb2492e8dd36436295a536084a6415
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ALDH3B1 KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

5.49e-061942198b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ALDH3B1 KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

5.49e-0619421987a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

OIP5 MCM3 KIF2C DMXL2 TOPBP1 CCNE1 MTMR7 HELLS

5.70e-061952198c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

ABCC3 DOCK11 MYO9B DDX60L DMXL2 ARHGEF10L ELL2 SBF2

5.70e-06195219855e25f702af19146a161861cfd15f40bbda1dc35
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DZIP1L ALDH3B1 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

6.14e-06197219871fea4aa6ce96c7693fa94792d08770622873850
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP32 ITPR2 KMT2C NF1 KDM6A TCF12 SBF2 SPIDR

6.62e-06199219894b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DZIP1L KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

6.86e-0620021986a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellSigmoid-(6)_Macrophage-(61)_LYVE1_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

CUEDC1 RGL1 RBP7 ALDH3B1 DNM1 DMXL2 ARHGEF10L FAM20A

6.86e-062002198bc0280d52e4edc2c5edf4ead164a1c7cf3fccd60
ToppCellSigmoid-Macrophage-LYVE1_Macrophage|Sigmoid / Region, Cell class and subclass

CUEDC1 RGL1 RBP7 ALDH3B1 DNM1 DMXL2 ARHGEF10L FAM20A

6.86e-062002198851a1b372ddbec522829069e69ed36a1f4832131
ToppCell(61)_LYVE1_Macrophage|World / shred on Cell_type and subtype

NLRC4 CUEDC1 RGL1 RBP7 ALDH3B1 DMXL2 ARHGEF10L FAM20A

8.52e-062062198711e961a9a03bfd2f0958bd14f25f7f207a2f2b5
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABCC4 STARD8 DOCK11 LDAH AGAP2 RPGRIP1 ICE1

1.05e-0515221970652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FZD7 RAB40AL PLA2G2A C1S WEE1 CPD ZNF432

1.24e-051562197bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCC4 CTTNBP2 MAOB FZD7 DNM1 DIRAS1 GRIK5

1.46e-0516021978a4746463ca1976f7d6de803496c851249ced797
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

KIF2C TAF1A FSD1 CFAP210 ZNF432 SMO CXCR1

1.58e-051622197a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPRASP1 GRIK5 RGS7 CCNE1 MTMR7 NEURL1 DIRAS2

2.08e-05169219796a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ITGA6 ITPR2 STIM1 LRRC9 NEURL1 EXOSC7

2.08e-0516921974b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ITGA6 ITPR2 STIM1 LRRC9 NEURL1 EXOSC7

2.08e-051692197a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCelldroplet-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC27A4 BBOF1 SYNE1 CPD GSR ARAP3 TTC23

2.16e-051702197dbd6c9c7be824a1ff1b31af791064127cafbd194
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC3 ARHGEF11 HNF4A LCN15 MTMR8 CCNE1 OVOL1

2.42e-05173219781c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ITGA6 ITPR2 STIM1 LRRC9 NEURL1 EXOSC7

2.42e-0517321970bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 CTTNBP2 ITGA6 STIM1 LRRC9 NEURL1 EXOSC7

2.60e-05175219798947a226b5a2ac7091ff9d34243ea7736add973
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

ABCC3 CTTNBP2 STARD8 DZIP1L RGL1 DMXL2 FAM20A

3.11e-0518021977be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 CTTNBP2 MAOB ITGA6 AHR WEE1 OVOL1

3.46e-05183219726b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HNF4A ALDH3B1 DNAH6 BBOF1 CCDC146 CFAP210 ALX1

3.46e-05183219758847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

DOCK11 ITGA6 NLRC4 ITPR2 ELOC SAR1B SPIDR

3.58e-0518421979c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ABCC4 MYCBP2 TRPM7 ITPR2 DMXL2 NUP155 HELLS

3.84e-0518621978571956890fc9894d766ba294a28e376b4aba428
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic|GI_large-bowel / Manually curated celltypes from each tissue

STARD8 RGL1 RBP7 ALDH3B1 DMXL2 ARHGEF10L FAM20A

4.11e-051882197d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

ALDH3B1 KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210

4.11e-0518821978f30535a32968a81a304315a49c0d90a77d36948
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 TRPM7 TASOR2 KMT2C NF1 KDM6A MAP3K2

4.11e-051882197ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes|GI_large-bowel / Manually curated celltypes from each tissue

STARD8 RGL1 RBP7 ALDH3B1 DMXL2 ARHGEF10L FAM20A

4.11e-0518821970bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

PTGIS PLA2G2A C1S ZFHX4 GADL1 SMO CXCR1

4.25e-05189219787189275234b5d59484c58acbb14a09903f2b578
ToppCellmild-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ACP6 TEX2 DZIP1L NLRC4 SYNE1 VEPH1 CDC14B

4.25e-05189219794dd5d4d815449feff7ce157fe7f8234f7c81422
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

4.39e-0519021979ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellcontrol-Myeloid-Immature_Neutrophils_1|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ACP6 TEX2 DZIP1L NLRC4 SYNE1 VEPH1 CDC14B

4.39e-05190219738e83337c70c8734b63f8589ba59e0f98603f94c
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

4.39e-051902197833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DZIP1L KIAA2012 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210

5.01e-0519421974a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC3 DOCK11 MYO9B TEX2 DDX60L DMXL2 ARHGEF10L

5.01e-05194219769cf7c989ac355c459db13f9d4267b55adc3c174
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NLRC4 NALCN ZNF347 TNFAIP8L2 NEURL1 ZNF654 HELLS

5.18e-051952197c96755d2eb98112b703b5dbee9c88730ace7dcbf
ToppCellBronchus_Control_(B.)-Immune-TX-TRAM-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

TNFAIP8L2 KHDRBS2 MTMR8 CCNE1 FMNL3 GTPBP2 LILRA4

5.18e-051952197dabf667875ed48fdce4f803f5ead39c71a6df42b
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DZIP1L ALDH3B1 KIAA2012 DNAH6 BBOF1 CCDC146 CCDC65

5.35e-051962197de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellCOVID-19_Severe-Neu_2|World / 5 Neutrophil clusters in COVID-19 patients

ACP6 ITGA6 RIOK3 ALDH3B1 SYNE1 VEPH1 CDC14B

5.35e-05196219716359a56297f0558fc93fa52563cce0c53def167
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB PTGIS C1S DNM1 ARHGEF10L MYH14 SMO

5.35e-0519621972029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

ALDH3B1 KIAA2012 DNAH6 CCDC146 SYNE1 CCDC65 DIRAS2

5.52e-051972197fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DZIP1L DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

5.52e-0519721976865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DZIP1L DNAH6 CCDC146 SYNE1 CFAP210 LRRC9 ZFHX2

5.52e-05197219774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DZIP1L DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

5.52e-051972197e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DZIP1L DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

5.52e-051972197d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellCOVID-19_Severe-Neu_2|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients

ACP6 ITGA6 RIOK3 ALDH3B1 SYNE1 VEPH1 CDC14B

5.52e-051972197945f19475905cdedf232315eea1076ca0b753b67
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC3 RIOK3 LCN15 VEPH1 ABCC5 MYH14 NEURL1

5.70e-051982197efdbac7a3a02bff4ca48841772e0c136556c2b9b
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC3 DOCK11 MYO9B NLRC4 DDX60L DMXL2 ARHGEF10L

5.70e-051982197e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTA2 SMG1 NCKAP1 SPTBN1 CSDE1 OGDH RAB18

5.70e-0519821972f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTA2 SMG1 NCKAP1 SPTBN1 CSDE1 OGDH RAB18

5.70e-051982197f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DZIP1L DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

5.70e-051982197ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellmLN-(5)_Dendritic_cell-(53)_Lymphoid_DC|mLN / shred on region, Cell_type, and subtype

ABCC4 CTTNBP2 ANKRD20A2P ANKRD20A3P PHKA1 ANKRD20A4P ANKRD20A1

5.70e-051982197da84c76afe835aeee39da04b63c03549218b5d91
ToppCellmLN-Dendritic_cell-Lymphoid_DC|mLN / Region, Cell class and subclass

ABCC4 CTTNBP2 ANKRD20A2P ANKRD20A3P PHKA1 ANKRD20A4P ANKRD20A1

5.70e-0519821973965a9f1e8a51a196e5349aaca5fa5ed1cd8ee92
ToppCellmLN-Macrophage-Macrophage|mLN / Region, Cell class and subclass

STARD8 DZIP1L CUEDC1 RGL1 RBP7 DMXL2 FAM20A

5.88e-0519921976bbec8450afb30347b07da28401a698fc51a3c53
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCC3 NCKAP1 MYCBP2 ATP8B1 PLEKHH1 CPD ELL2

5.88e-05199219732bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTA2 SMG1 NCKAP1 SPTBN1 ITGA6 CSDE1 OGDH

5.88e-0519921978d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellmLN-(6)_Macrophage-(60)_Macrophage|mLN / shred on region, Cell_type, and subtype

STARD8 DZIP1L CUEDC1 RGL1 RBP7 DMXL2 FAM20A

5.88e-0519921971ea28b832c6173b1b58da432aaf21e6cd291561e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

MCM3 KIF2C DMXL2 SMPD4 NUP155 SNAI1 HELLS

6.07e-052002197d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

R3HCC1L ANKRD20A4P DMXL2 CHD7 THADA UGGT2 HELLS

6.07e-052002197118321ac443feb42aee171baccfc4610f00a8822
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTGIS RGL1 DNM1 SYNE1 VEPH1 FMNL3 ZFHX4

6.07e-052002197a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

ALDH3B1 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

6.07e-0520021973305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-ILC|Multiple_Sclerosis / Disease, condition lineage and cell class

SPTLC3 GPRASP1 INPP5B CLHC1 THAP11 ZNF432 DEPDC7

6.07e-052002197ab9bdc9365cbdffe4ed246ce0c8a008a390e387e
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ALDH3B1 KIAA2012 DNAH6 BBOF1 CCDC146 CFAP210 CCDC65

6.07e-0520021978441e289377215a6877640946fe3f6de1f456502
ToppCell(10)_Ciliated|World / shred by cell type by condition

ALDH3B1 DNAH6 BBOF1 CCDC146 SYNE1 CFAP210 CCDC65

6.07e-0520021971b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SPTBN1 ITGA6 KMT2C AHR DGKZ CHD7 ARAP3

6.07e-052002197dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell|GW13 / Sample Type, Dataset, Time_group, and Cell type.

MCM3 KIF2C DMXL2 SMPD4 NUP155 SNAI1 HELLS

6.07e-0520021973d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-T/NK_proliferative|Bac-SEP / Disease, condition lineage and cell class

OIP5 MCM3 ANKRD20A3P KIF2C MTMR8 CCNE1 HELLS

6.07e-052002197a09b4e07b273880e94032b939ab191caaf6d656e
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ANKRD20A2P PGAM5 CSDE1 PUM3 DIRAS1 FSD1

6.51e-051392196aefcfda2b2db302ce4b3d2a09f767be0b1c3ac6c
ToppCell356C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ANKRD20A2P PGAM5 CSDE1 PUM3 DIRAS1 FSD1

6.51e-051392196b9c2dfab119ac0efdf931bb2910e82bccdb4e48d
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|367C / Donor, Lineage, Cell class and subclass (all cells)

MCM3 ITPR2 SRGAP3 DDX60L FMNL3 LMBR1L

9.56e-05149219641f28138bde45d0b814e116837e5a32b5e80d54a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B1 VEPH1 ARHGEF10L OVOL1 FAM20A DIRAS2

1.03e-04151219610da94037225a71844281ddcb395072250a78094
ToppCellileum-BEST4+_Enterocytes|ileum / shred on tissue and cell subclass

MCM3 ITPR2 ELOC VEPH1 ELL2 NEURL1

1.15e-041542196608e9c982125e0c2c15b86b1920813845a0db81f
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA2012 DNAH6 CCDC146 CFAP210 LRRC9 ANKEF1

1.19e-0415521965f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA2012 DNAH6 CCDC146 CFAP210 LRRC9 ANKEF1

1.19e-0415521960944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellfacs-Spleen-nan-24m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH6 DMXL2 SYNE1 CPD GSR ARAP3

1.23e-041562196034d4359359a44c205c6931f38a375271ac2752b
ToppCellfacs-Spleen-nan-24m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH6 DMXL2 SYNE1 CPD GSR ARAP3

1.23e-04156219621267718d3a3dc19988663b6846aed8bb3eae836
ToppCellfacs-Spleen-nan-24m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH6 DMXL2 SYNE1 CPD GSR ARAP3

1.23e-0415621962a4dac4100c0339aad4905b8eaca6e8fe806718b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ITGA6 ITPR2 STIM1 NEURL1 EXOSC7

1.27e-041572196c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

ABCC3 ABCC4 MAOB RBP7 PLA2G2A PABPC1L

1.32e-041582196ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 CTTNBP2 C1S WDR17 ZFHX4 CNTNAP4

1.41e-041602196c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC4 ITGA6 ITPR2 STIM1 LRRC9 EXOSC7

1.41e-041602196174a4ab27114efcc63be36929b80680be3c35c9b
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR64 CTTNBP2 C1S WDR17 ZFHX4 CNTNAP4

1.41e-04160219625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SPTLC3 WDR64 FZD7 IFNB1 ZFHX4 DEPDC7

1.46e-0416121967e0b8119cea208c0b4a0dffdf94ff6137d0b4c90
ToppCellControl-Lymphocyte-B-Plasmablast|Control / Disease, Lineage and Cell Type

ABCC4 CAGE1 PHKA1 UGT2B17 ELL2 HELLS

1.51e-04162219667b32c40cc180c5ebbfd901a417b5be469500110
ToppCellBL-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CTTNBP2 MAOB AHR INTS6L GSR SNAI1

1.51e-04162219625ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPTLC3 WDR64 FZD7 IFNB1 ZFHX4 DEPDC7

1.51e-0416221962fd6e8f48b48d509a7533cec2f79089513c34a2f
Drugtetramethylrosamine

ABCC3 ABCC4 MAOB ABCC2 ABCC5 OGDH

1.97e-09142176CID000443313
DrugAC1NE3ZR

ABCC3 ABCC4 CTTNBP2 ABCC2 ABCC5 FSD1

1.37e-07262176CID004636208
DrugSB 203580; Up 200; 1uM; MCF7; HT_HG-U133A

NCKAP1 ZNF236 CWC25 LDAH FZD7 KDM6A BBOF1 TCF12 WDR47 GTF2E1 MPHOSPH9 SPIDR

4.73e-07198217126915_UP
DrugVX-710

ABCC3 ABCC4 ABCC2 ABCC5 IFNB1

1.73e-06222175CID000406509
Drugyohimbine; Up 200; 22.9uM; MCF7; HT_HG-U133A_EA

FOXRED2 NF1 AHR DNM1 SLC25A17 NCSTN MED1 ARHGEF10L UGGT2 MPHOSPH9 MAP3K2

2.74e-06194217111119_UP
Drugharmol sulfate

ABCC3 ABCC4 ABCC2 ABCC5

5.36e-06132174CID005488302
Drugchrysophanic acid

ABCC4 CYP8B1 AHR ABCC2

5.36e-06132174ctd:C027113
Drug3 alpha,6 alpha-dihydroxy-5 beta-cholanoic acid

ABCC3 CYP8B1 UGT2B15 ABCC2 SYNE1

7.40e-06292175CID000006747
DrugCDCF

ABCC4 ABCC2 ABCC5 OGDH

7.45e-06142174CID000132525
Drugsoybean oil, phospholipid emulsion

ABCC3 ABCC4 ABCC2

8.42e-0652173ctd:C545823
Drugdavidigenin

ABCC3 ABCC4 ATP8B1 HNF4A ABCC2

8.81e-06302175CID000442342
DrugAC1L9E0Q

ABCC3 ABCC4 UGT2B15 ABCC2 ABCC5

8.81e-06302175CID000443095
DrugPAK-104P

ABCC3 ABCC4 ABCC2 ABCC5

1.01e-05152174CID000131368
DrugAC1L4BIC

ABCC3 ABCC4 ABCC2 ABCC5

1.34e-05162174CID000153998
Drugallyl alcohol

ABCC3 ABCC4 ABCC2 ABCC5 GSR

1.43e-05332175ctd:C006463
Druglithocholic acid

ABCC3 CYP8B1 STIM1 UGT2B15 UGT2B17 CASP9 MED1 SNAI1

1.57e-051162178CID000009903
Drugmonochlorobimane

ABCC3 ABCC4 ABCC2 ABCC5 GSR

1.67e-05342175CID000114886
DrugAC1NB6SN

ABCC3 ABCC2 ABCC5

1.67e-0562173CID004488324
Drug1-naphthylglucuronide

ABCC3 ABCC4 ABCC2

1.67e-0562173CID000114851
DrugAC1LAHTK

ABCC3 ABCC4 ABCC5

1.67e-0562173CID000468713
DrugFenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A

GPRASP1 ABCC3 SPTBN1 ITPR2 CEP68 NF1 BBOF1 CEP162 GTPBP2 SPIDR

1.88e-05195217103721_DN
Drugfluphenazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A

MTA2 INPP5B ARHGEF11 STIM1 CEP68 ASCC2 C1S OGDH RGS7 MYH14

2.05e-05197217104461_DN
DrugN-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A

MTA2 SPTBN1 CWC25 PTGIS NF1 CEP162 CASP9 CDC14B OVOL1 UGGT2

2.05e-05197217103836_DN
Drugacetaminophen glucuronide

ABCC3 ABCC4 UGT2B15 UGT2B17 ABCC2 ABCC5

2.07e-05592176CID000083944
Drug6-methylpurine-2'-deoxyriboside

ABCC3 ABCC4 ATP8B1 AHR ABCC2 ABCC5

2.51e-05612176CID000097184
DrugCalcein AM

ABCC3 ABCC4 ITGA6 AHR ABCC2 ABCC5

2.76e-05622176CID000390986
DrugApa-sg

ABCC3 ABCC4 ABCC2 ABCC5

2.78e-05192174CID000126348
DrugO746

ABCC3 ABCC4 ABCC2 ABCC5

3.45e-05202174CID006327063
DrugCiprofloxacin

ABCC3 ABCC4 ABCC2 CASP9 CCNE1 SNAI1

3.62e-05652176ctd:D002939
Drugharmol

ABCC3 ABCC4 UGT2B15 UGT2B17 ABCC2

3.77e-05402175CID000068094
Drugsodium cholate

ABCC3 ABCC4 CYP8B1 ATP8B1 HNF4A CFHR4 UGT2B15 UGT2B17 ABCC2 SLC27A4 SYNE1 ABCC5 CASP9 MED1

4.02e-0540821714CID000000303
DrugHMDS

ARHGAP32 UGT2B15 SYNE1 CPD

4.23e-05212174CID000013838
DrugAC1Q6O8B

ABCC4 CYP8B1 HNF4A PTGIS ABCC2

4.26e-05412175CID000000334
DrugTAK-875

ABCC3 ABCC4 ABCC2

4.62e-0582173ctd:C557331
Drugcalcein AM

ABCC3 ABCC4 ABCC2

4.62e-0582173ctd:C085925
Drugtolvaptan

ABCC3 ABCC4 ABCC2

4.62e-0582173ctd:C116664
DrugAC1Q5X3R

ABCC3 ABCC4 ABCC2 ABCC5

5.13e-05222174CID000108075
Drugoltipraz

ABCC3 ABCC4 AHR UGT2B15 UGT2B17 ABCC2 ABCC5 GSR

5.22e-051372178CID000047318
Drugsulfobromophthalein

ABCC3 ABCC4 ABCB7 ATP8B1 ABCC2 ABCC5 RAB18

5.92e-051032177CID000005345
Drughydroxyrubicin

ABCC3 ABCC4 ABCC2 ABCC5

6.16e-05232174CID000072398
DrugTBHQ

ABCC3 ABCC4 STIM1 NF1 AHR ABCC2 ABCC5 GSR

6.40e-051412178CID000016043
DrugDentacolor

ARHGAP32 KDM5D DNM1

6.88e-0592173CID003035662
DrugTetracycline

ACP6 SPTLC3 ABCC3 ABCC4 MAOB CYP8B1 RIOK3 HNF4A LDAH PLA2G2A ABCC2 SLC25A17 WEE1 PKD1L3 CDC14B GSR GTPBP2 TTC23

7.81e-0566821718ctd:D013752
DrugPMEG

ABCC3 ABCC4 ABCC2 ABCC5

8.68e-05252174CID000064989
Drugphenolphthalein glucuronide

UGT2B15 ABCC2

9.04e-0522172ctd:C016651
Drug5(6)-carboxy-2',7'-dichlorofluorescein

ABCC3 ABCC2

9.04e-0522172ctd:C053897
Drug2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein

ABCC4 ABCC5

9.04e-0522172ctd:C043829
Drugbenzylamine

MAOB AHR

9.04e-0522172ctd:C030796
DrugE3040 glucuronide

ABCC3 ABCC2

9.04e-0522172CID000443294
DrugMethoxsalen

ABCC3 ABCC4 CYP8B1 AHR CASP9

9.21e-05482175ctd:D008730
Drugalfacalcidol

ABCC3 ABCC4 ABCC2 MED1

1.02e-04262174ctd:C008088
DrugBetamethasone [378-44-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A

ABCC4 NCKAP1 ITGA6 RIOK3 CWC25 SALL2 NF1 DNM1 GTPBP2

1.07e-0419421795328_DN
DrugPipenzolate bromide [125-51-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A

NCKAP1 CWC25 FZD7 SUN2 KDM6A CFAP410 CEP162 NCSTN WDR47

1.07e-0419421793460_DN
DrugLithocholic Acid

ABCC3 ABCC4 CYP8B1 HNF4A STIM1 UGT2B15 UGT2B17 ABCC2 ABCC5 CASP9

1.08e-0424021710ctd:D008095
DrugSulindac [38194-50-2]; Up 200; 11.2uM; PC3; HT_HG-U133A

ABCC3 INPP5B ITGA6 RIOK3 KDM6A WEE1 CPD GSR GTPBP2

1.11e-0419521791815_UP
DrugTestosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A

MYO9B KDM5C ZNF236 CWC25 CEP68 NF1 SUN2 KDM6A CASP9

1.11e-0419521792649_DN
DrugClorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A

SPTLC3 ATP9B ARHGEF11 FZD7 FOXRED2 WEE1 CEP162 KHDRBS2 GRIK5

1.15e-0419621797025_UP
DrugAC1Q5QTP

ABCC3 ABCC4 ABCC2 ABCC5

1.19e-04272174CID000071324
Drugchrysin

ABCC3 AHR UGT2B15 ABCC2 ABCC5 CASP9 GSR

1.19e-041152177ctd:C043561
DrugCyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; PC3; HG-U133A

SPTBN1 RIOK3 ATP8B1 CEP68 KIF2C GRIK5 AKAP11 MPHOSPH9 EXOSC7

1.20e-0419721791938_DN
DrugCefamandole sodium salt [30034-03-8]; Down 200; 8.2uM; MCF7; HT_HG-U133A

MYO9B ATP9B CWC25 CEP68 FOXRED2 CEP162 CPD OGDH CDC14B

1.20e-0419721793436_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A

INPP5B KDM5C ATP9B ARHGEF11 ITPR2 CEP68 DNM1 CDC14B SPIDR

1.20e-0419721791640_DN
DrugTetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A

NCKAP1 INPP5B SPTBN1 NF1 MED1 WDR47 LMBR1L UGGT2 SPIDR

1.20e-0419721796233_UP
DrugOfloxacin [82419-36-1]; Up 200; 11uM; PC3; HT_HG-U133A

STARD8 LDAH ITPR2 NF1 R3HCC1L MYH14 NEURL1 ZFHX2 SPIDR

1.25e-0419821793673_UP
DrugSulfanilamide [63-74-1]; Down 200; 23.2uM; MCF7; HT_HG-U133A

ARHGEF11 SUN2 KDM6A CFAP410 WEE1 CEP162 CDC14B TTC23 SPIDR

1.25e-0419821793449_DN
Drugcarbonyl sulfide

INHBB KDM5C KDM5D SALL2 SCO1 KDM6A SYNE1

1.26e-041162177CID000010039
Drughexabromodiphenyl ether 154

AHR CASP9 TNNI1

1.33e-04112173ctd:C533761
Drugphyscione

ABCC3 CYP8B1 ABCC2

1.33e-04112173ctd:C008905
Drugindoleacetic acid

ABCC4 AHR GSR

1.33e-04112173ctd:C030737
DrugW-13, hydrochloride; Up 200; 10uM; MCF7; HG-U133A

GPRASP1 STARD8 ITPR2 SUN2 BBOF1 DMXL2 CEP162 OVOL1 SMO

1.34e-042002179643_UP
DrugAC1NQGK1

ABCC3 UGT2B15 UGT2B17 ABCC2 ABCC5

1.36e-04522175CID005195977
DrugTexas Red

ABCC3 ABCC4 ABCC2 ABCC5

1.37e-04282174CID000452705
DrugButylated Hydroxyanisole

ABCC3 ABCC4 AHR ABCC2 ABCC5 CCNE1 HELLS

1.40e-041182177ctd:D002083
Drugdiallyl disulfide

ABCC3 ABCC4 CASP9 GSR SNAI1

1.77e-04552175ctd:C028009
DrugPGF1|A

ABCC3 ABCC4 PTGIS ABCC5

1.81e-04302174CID000004957
Drugedatrexate

ABCC3 ABCC4 SYNE1 ABCC5

1.81e-04302174CID000054586
DiseaseColorectal Carcinoma

ABCC3 ABCC4 STARD8 TRPM7 OBSCN KMT2C NF1 ABCC2 KDM6A MYOT SYNE1 ABCC5 ARHGEF10L ARAP3 NEURL1 ZNF432

3.98e-0570220716C0009402
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

1.46e-0432072EFO_0800574
Diseaseneutrophil gelatinase-associated lipocalin measurement

CHD7 ELL2

1.46e-0432072EFO_0021964
DiseaseColorectal Neoplasms

ABCC3 ABCC4 STARD8 TRPM7 ABCC2 SYNE1 ABCC5 NEURL1 ZNF432

1.59e-042772079C0009404
Diseaseattention deficit hyperactivity disorder, conduct disorder

ATP8B1 RGL1 KIAA2012 PKD1L3

1.76e-04402074EFO_0003888, EFO_0004216
DiseaseX-25937 measurement

UGT2B15 UGT2B17

2.91e-0442072EFO_0800937
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

2.91e-0442072DOID:0060809 (implicated_via_orthology)
Diseaseetiocholanolone glucuronide measurement

NLRC4 UGT2B15 UGT2B17

3.03e-04192073EFO_0800362
Diseasecholestasis (biomarker_via_orthology)

ABCC3 ABCC4 MAOB ABCC2

3.89e-04492074DOID:13580 (biomarker_via_orthology)
Diseaseadenoid cystic carcinoma (is_implicated_in)

KMT2C KDM6A

4.83e-0452072DOID:0080202 (is_implicated_in)
Diseasecomplement C1s subcomponent measurement

CFHR4 C1S

7.21e-0462072EFO_0008091
Diseaseautism spectrum disorder (implicated_via_orthology)

ARHGAP32 KDM5C KDM5D CSDE1 CHD7 CNTNAP4

7.35e-041522076DOID:0060041 (implicated_via_orthology)
Diseasepancreatic cancer (is_marker_for)

ABCC3 AHR ABCC2 ABCC5 SMO

7.43e-041012075DOID:1793 (is_marker_for)
Diseaseobesity (implicated_via_orthology)

HNF4A ITPR2 STIM1 TCF12 THADA ZFHX4 ZFHX2

8.44e-042152077DOID:9970 (implicated_via_orthology)
Diseasemean platelet volume

ARHGAP32 STARD8 DOCK11 MYO9B TEX2 SPTBN1 RSF1 ITGA6 MCM3 CUEDC1 STIM1 QRFPR KIF28P TCF12 ABCC5 CHD7 LRRC8D

9.11e-04102020717EFO_0004584
DiseaseX-12244--N-acetylcarnosine measurement

ABCC4 GADL1

1.00e-0372072EFO_0021299
Diseasecentronuclear myopathy (implicated_via_orthology)

MTMR8 MTMR7

1.00e-0372072DOID:14717 (implicated_via_orthology)
DiseaseX-24574 measurement

UGT2B15 UGT2B17

1.00e-0372072EFO_0800897
Diseaseblood N-acetylcarnosine measurement

ABCC4 GADL1

1.00e-0372072EFO_0022217
Diseasebilirubin metabolic disorder (biomarker_via_orthology)

ABCC3 ABCC2

1.00e-0372072DOID:2741 (biomarker_via_orthology)
DiseaseCholestasis

ABCC3 CYP8B1 ABCC2 GTPBP2 SNAI1

1.09e-031102075C0008370
DiseaseIntellectual Disability

FRMPD4 KDM5C GTF3C3 CSDE1 KMT2C NF1 SRGAP3 SYNE1 RGS7 GTPBP2

1.31e-0344720710C3714756
DiseaseAmyotrophic Lateral Sclerosis, Guam Form

TRPM7 CFAP410 GSR

1.32e-03312073C0543859
DiseaseN-acetylcarnosine measurement

ABCC4 GADL1

1.33e-0382072EFO_0022101
DiseaseCholestasis of pregnancy

ATP8B1 ABCC2

1.33e-0382072C0268318
Diseasedeoxycholic acid glucuronide measurement

UGT2B15 UGT2B17

1.33e-0382072EFO_0800575
DiseaseRheumatoid Arthritis

ABCC3 ABCC4 ITGA6 AHR ABCC2 ABCC5

1.48e-031742076C0003873
DiseaseMalignant neoplasm of breast

STARD8 OBSCN ATP8B1 RGL1 NF1 SRGAP3 AHR AGAP2 SYNE1 MTMR8 IFNB1 CCNE1 ARAP3 ANKEF1 ZNF432 SNAI1 HSPA14

1.58e-03107420717C0006142
Diseasefatty liver disease (biomarker_via_orthology)

ABCC3 ABCC2 SLC27A4

1.59e-03332073DOID:9452 (biomarker_via_orthology)
Diseaseandrosterone sulfate measurement

FAM200A UGT2B15 UGT2B17

1.59e-03332073EFO_0021117
Diseasecentronuclear myopathy X-linked (implicated_via_orthology)

MTMR8 MTMR7

1.71e-0392072DOID:0111225 (implicated_via_orthology)
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

2.12e-03102072EFO_0022090
Diseasetriacylglycerol 54:1 measurement

ZFHX4 ZNF432

2.12e-03102072EFO_0010419
DiseaseGlobal developmental delay

FRMPD4 KDM5C GTF3C3 CSDE1 GTPBP2

2.52e-031332075C0557874
DiseaseDNA repair protein RAD51 homolog 4 measurement

UGT2B15 UGT2B17

2.58e-03112072EFO_0801531
DiseaseCarcinoma, Transitional Cell

KMT2C KDM6A IFNB1

2.98e-03412073C0007138
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

UGT2B15 UGT2B17

3.09e-03122072EFO_0800291
Diseaseglycochenodeoxycholate glucuronide (1) measurement

ABCC3 ABCC2

3.63e-03132072EFO_0800474
DiseaseX-24588 measurement

ABCC3 ABCC2

3.63e-03132072EFO_0800898
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

UGT2B15 UGT2B17

3.63e-03132072EFO_0800293
DiseaseX-19141 measurement

UGT2B15 UGT2B17

3.63e-03132072EFO_0800799
Diseasephosphatidylcholine measurement

SPTLC3 ZGRF1 HNF4A PLEKHH1 CEP162 CHD7 GRIK5

4.06e-032842077EFO_0010226
Diseasemalignant pleural mesothelioma (is_marker_for)

KDM6A SMO

4.22e-03142072DOID:7474 (is_marker_for)
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

UGT2B15 UGT2B17

4.22e-03142072EFO_0800283
DiseaseNeurodevelopmental Disorders

NCKAP1 KMT2C SRGAP3 DNM1

4.22e-03932074C1535926
Diseaseautism

MYO9B KDM5D CSDE1

4.67e-03482073EFO_0003758
Diseasenon-high density lipoprotein cholesterol measurement

ATP8B1 HNF4A AHR UGT2B15 UGT2B17 SLC25A17 TCF12 ADNP2 DGKZ CHD7 GRIK5 THADA

4.73e-0371320712EFO_0005689
Diseaselevel of C-X-C motif chemokine 3 in blood serum

TNFAIP8L2 NCSTN

4.84e-03152072OBA_2041208
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

CEP68 NF1 UGT2B15

4.94e-03492073EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Diseaseacute myeloid leukemia (is_marker_for)

ABCC3 NF1 GSR

4.94e-03492073DOID:9119 (is_marker_for)
Diseasefree androgen index

HNF4A UGT2B15 UGT2B17 TCF12 CHD7 THADA OVOL1 ZFHX4

5.10e-033742078EFO_0007005
DiseaseMedulloblastoma

KDM6A CCNE1 SMO

5.23e-03502073C0025149
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

5.51e-03162072DOID:0050888 (implicated_via_orthology)
DiseaseInherited oocyte maturation defect

ZP2 FBXO43

5.51e-03162072cv:CN238505
DiseasePheochromocytoma, Extra-Adrenal

MAOB NF1

5.51e-03162072C1257877
DiseaseEndometrioma

MTA2 ABCC4 MAOB PLA2G2A MED1

5.67e-031612075C0269102
DiseaseEndometriosis

MTA2 ABCC4 MAOB PLA2G2A MED1

5.67e-031612075C0014175
DiseaseSquamous cell carcinoma of the head and neck

ABCC2 WEE1 CCNE1

5.84e-03522073C1168401
Diseasemuscular dystrophy (is_implicated_in)

MYOT SYNE1

6.21e-03172072DOID:9884 (is_implicated_in)
Diseaseextrahepatic cholestasis (biomarker_via_orthology)

ABCC4 CYP8B1

6.21e-03172072DOID:13619 (biomarker_via_orthology)
DiseaseX-21441 measurement

ABCC3 ABCC2

6.21e-03172072EFO_0800814
Diseasemetabolite measurement

ABCC3 ABCC4 ITPR2 AHR UGT2B15 UGT2B17 ABCC2 CASP9 ICE1 GADL1

6.45e-0356020710EFO_0004725
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

UGT2B15 UGT2B17

6.96e-03182072EFO_0800288
Diseasedisease free survival

CCDC168 ICE1

6.96e-03182072EFO_0000409

Protein segments in the cluster

PeptideGeneStartEntry
MVEFLLKKKASSHAV

ANKRD20A1

181

Q5TYW2
SSIAVLRMKAKEHTA

ALX1

306

Q15699
GTEHLRKRNTKLPFM

AHR

391

P35869
MRKVSFLHRKDVLGD

ARHGEF10L

266

Q9HCE6
KMVLTRAKASELHSV

CFAP410

6

O43822
FIDPLMNKKARISHL

ELL2

326

O00472
DIKRASQLASKMHSL

CAGE1

606

Q8TC20
LRTGMLELRGHKAKV

ARAP3

396

Q8WWN8
MVEFLLKKKASTHAV

ANKRD20A8P

181

Q5CZ79
SRDGKFIHRMKLESA

CWC25

381

Q9NXE8
AKDRLTIGKHLDMGS

CEP68

421

Q76N32
ITMLRKKIVHFTGSD

CDC14B

111

O60729
MVEFLLKKKASSHAV

ANKRD20A4P

181

Q4UJ75
RVGKIVMTAAAKHLT

ALDH3B1

191

P43353
HERMQLSKDGKILTI

CEACAM20

111

Q6UY09
RLSHSRKKLMEIFHI

ASCC2

311

Q9H1I8
AITISKGKIMIHSRE

CCDC65

271

Q8IXS2
KTSLMIRHDKVLRSF

GSR

256

P00390
RASLKTLHRMAEKVG

GTPBP2

121

Q9BX10
FKSLDLTTRKMIHEG

ARHGEF11

956

O15085
MVIRETGSSKLKHFR

CCNE1

336

P24864
KFKTMQSDGILLHRE

CNTNAP4

211

Q9C0A0
DMFADRLSKSIIKHS

AKAP11

936

Q9UKA4
THGKEMDLLRTTVKV

AGAP2

721

Q99490
LGHELSMEILAKAKA

ANKEF1

91

Q9NU02
KHTGAVSARNIMLLK

CSDE1

166

O75534
MDLGKVRRAKAILSH

DMXL2

1356

Q8TDJ6
SKGKTDLLVLFLMDH

DEPDC7

401

Q96QD5
AKEIGMIHTELKAVR

BBOF1

136

Q8ND07
ITMLRKKIVHFTGSD

CDC14C

81

A4D256
RKNVEGLDLLFMSHK

CHD7

2516

Q9P2D1
GLDLLFMSHKRTSLS

CHD7

2521

Q9P2D1
NMTGKHSRLTEKLLE

FAM200A

216

Q8TCP9
HRGLSLAKAFQMVKS

DUSP28

121

Q4G0W2
KRFFVSLLHGVLTSM

ATP8B1

1031

O43520
LGFDMSELKNVKHRL

ADNP2

1111

Q6IQ32
TARDALGIKHTMVKI

R3HCC1L

691

Q7Z5L2
GLKFARKHSMLFIEA

RAB18

136

Q9NP72
IALRSHLKSFSMAKG

RAB40AL

216

P0C0E4
KDTRALRKALTHLEM

MTA2

611

O94776
SVLRTIHGKEMSKIA

QRFPR

251

Q96P65
HLTSRELLMKEGTSK

RGL1

371

Q9NZL6
RMRSNLLKTHKFIVG

INTS6L

526

Q5JSJ4
IAEIIRSFKGHVRKM

PUM3

231

Q15397
RVRDSTLHLKEGMKG

ITPR2

1851

Q14571
RGYIILSHLSKLKMV

ABCC3

61

O15438
KHFTRDLMEKLKGRT

NCSTN

101

Q92542
ITLEGFRGLMKLKHL

LRRC9

751

Q6ZRR7
HRMIKLTTGKEAALS

PLA2G2A

26

P14555
MVEFLLKRKASSHAV

ANKRD20A2P

181

Q5SQ80
MGFILAHKARKLARL

MAOB

341

P27338
KLRALQSHSVMESKL

DZIP1L

291

Q8IYY4
MIQSLSLRKVEGIHK

DZIP1L

401

Q8IYY4
LKKRGHKVLLFSQMT

HELLS

611

Q9NRZ9
DKEGNSMSRHILKTL

LILRA4

61

P59901
SEPKMSAHVKRFVLR

KMT2C

4711

Q8NEZ4
RAHAEIRKMSLLKFL

MAGEA10

301

P43363
SVDVGRKHSITRKLM

MAGEE2

431

Q8TD90
ETSKMLVLRFLAKLH

MAGEL2

1191

Q9UJ55
ARGIIHMILKKGSES

NLRC4

51

Q9NPP4
RHIKAIMDAGIFIAK

MTMR7

311

Q9Y216
RHIKAIMDAGIFITK

MTMR8

311

Q96EF0
SHSKMLDKEVRAVFL

SBF2

346

Q86WG5
LHSIPKSFAELRKMT

LRRIQ4

246

A6NIV6
KLRDVEKGFMSSKHI

DNM1

571

Q05193
RLSLKAKVSDNMSHL

FSD1

131

Q9BTV5
HMGVLGTSKLYDIRK

PHKA1

501

P46020
KLSMHDRSLKVAAVV

ATP9B

711

O43861
AAMVTALRKLHAGKV

INHBB

101

P09529
AKEIHLRLGLMFKVN

KDM6A

166

O15550
LPTMLHKLKIRAESF

KDM5D

746

Q9BY66
LVSHLMSCKKGRVAI

DDX60L

1556

Q5H9U9
EHLLLGATKRSMVFK

HNF4A

226

P41235
GATKRSMVFKDVLLL

HNF4A

231

P41235
RARHKMTIAALESKL

MYH14

1826

Q7Z406
NLHMKRFVKDLGLSA

PCYOX1

96

Q9UHG3
KRMKLSSLDVFIIGA

SLC25A17

196

O43808
LLTVHRMNSAEGRKK

OR2T5

226

Q6IEZ7
KHSKFCRMGLILLVV

MINAR2

161

P59773
KDSKITDHFMRLPKA

PARG

406

Q86W56
ASLGLKFNKIVHSSM

PGAM5

136

Q96HS1
DALFRDKLKHMGKST

CUEDC1

301

Q9NWM3
AFKELGRMCQLHLKS

TCF12

596

Q99081
KAVELLDRSIHMKSL

MAP3K2

101

Q9Y2U5
RSKSLAFHTMLTKGV

VEPH1

446

Q14D04
ELGSVRMTLKKFHVL

MPHOSPH9

1011

Q99550
RKLHIDMTPFLKESG

KIAA2012

706

Q0VF49
KGKTRLLVTHSMHFL

ABCC2

811

Q92887
CRVFLGKKDHLSMST

LCN15

46

Q6UWW0
GAVVLLKRDMKSAHL

ITGA6

326

P23229
LQKTTGTMIHKLAAR

PARP4

1116

Q9UKK3
MLLNDRKVFVGHFKS

PABPC1L

161

Q4VXU2
MLAQLETLTGRKAKH

FOXRED2

476

Q8IWF2
VLKMPSLEGRHKAFS

OR5AP2

231

Q8NGF4
SKKHGKLITFLRTFM

ARHGAP32

336

A7KAX9
METGKRVGKVLHASL

EXOSC7

256

Q15024
KASLGLADHRELGKM

NCKAP1

501

Q9Y2A7
MGRAVKVLQLFKTLH

LYRM7

1

Q5U5X0
SKVHRALYSKGILLM

NUP155

406

O75694
LVSPKHALMVFRVAK

SMPD4

496

Q9NXE4
RDHGFLRTKMKVTLG

OVOL1

96

O14753
LLTVHRMNSAEGRKK

OR2T29

226

Q8NH02
VHDLHVGITKRLKTM

OBSCN

2731

Q5VST9
LTASAHIRMTDKKIL

OBSCN

5301

Q5VST9
LIRLATAHAKARMSK

MCM3

621

P25205
TEIGLHDLRKKMSII

ABCC4

1106

O15439
HAKFIASTGMDRSLK

PRPF19

486

Q9UMS4
PALQLVHELFMKSKR

FBXO43

441

Q4G163
GTKASAVSAIHKLMR

MON1A

621

Q86VX9
SSLARVAHKKGELSM

ABCC5

116

O15440
KKVMSILLHGDAAFA

OGDH

401

Q02218
MQRLSISKGHAFILV

DIRAS1

71

O95057
SLFRIRTIMKHDGTK

FZD7

446

O75084
MVEFLLKRKASSHAV

ANKRD20A3P

181

Q5VUR7
AKTMALTKARLVRAG

DNAH6

2951

Q9C0G6
GLTKIHSLPRSVFMK

ICE1

731

Q9Y2F5
EVMHTKKRLLGTFFR

DOCK11

1751

Q5JSL3
MRKNKAEHITVLLSG

CTTNBP2

1076

Q8WZ74
MQRLSISKGHAFILV

DIRAS2

71

Q96HU8
KLSIKGIEHFSLMLE

FRMPD4

236

Q14CM0
LLDTKSTDRKMTLLH

FMNL3

796

Q8IVF7
SLHFMVEVKGDLTAK

CASP9

196

P55211
DFTRGKLMSSLHLKR

IFNB1

131

P01574
FLKILAMHGLVSKEF

CXCR1

316

P25024
RLAKSKMLTPEHVFI

C1S

496

P09871
KRSLLSMLVEVHKGV

CPD

1201

O75976
VASLKEQMHKSRFLS

CEP162

756

Q5TB80
VKREHALTSGTIKAM

ELOC

31

Q15369
AKSNGMRFKLHDTLD

CFHR4

406

Q92496
FLAKMRGILKSIASA

COMMD1

51

Q8N668
DKAHILSMQKFGLRD

INPP5B

311

P32019
SRMSHALEEIKKFLV

KHDRBS2

146

Q5VWX1
GSALMSRKHRKLLHG

GADL1

306

Q6ZQY3
KGKLLMHFSVKTLEI

CCDC168

6546

Q8NDH2
DFLMGSSKDLAKHIR

DGKZ

491

Q13574
SISHLILRKASELGM

GRIK5

221

Q16478
MKKIEISGTCLSFHL

C9orf57

1

Q5W0N0
HLKLMRKIGKSVTAD

RSF1

71

Q96T23
KRKGEIAASIATHMR

SCO1

281

O75880
RQGFLERATLKKHML

SALL2

946

Q9Y467
IILRAKGRMHGKFSL

KIF2C

476

Q99661
SVLADAAMGKKVLHI

KIF28P

291

B7ZC32
FLKRMRTKHGDVFTV

CYP8B1

56

Q9UNU6
IILKSGRIMHGKFSL

KIF2B

431

Q8N4N8
EKLSKMSSLLERLHA

MED1

11

Q15648
RMLKKSGLVVEDHLF

LRRC8D

821

Q7L1W4
VARLIFSKMKETAHS

HSPA14

116

Q0VDF9
THNRLKSLMKILSEV

OIP5

206

O43482
ATGNAKTRFHVLKML

GPRASP1

1286

Q5JY77
VMRALLIHEKKTSSA

GTF2E1

321

P29083
RHRLKMSKVADSLLS

RGS7

271

P49802
AFDLLMKLSKTAVHF

THADA

806

Q6YHU6
RTKQTMHGILERSKF

TIGAR

61

Q9NQ88
KLLHERNASLVMTKA

RPGRIP1

281

Q96KN7
ESLGRAMTGLIKKHE

SYNE1

2376

Q8NF91
GLARMFSVTGKLLVK

LMBR1L

216

Q6UX01
ASFLTRMKEKHGDIF

PTGIS

51

Q16647
KLARGSLSVGDKDHM

PTGIS

216

Q16647
LMSKKIHLTENGIRV

LARS1

1151

Q9P2J5
SHKLMLEFHTLLRKS

TAF1A

306

Q15573
HLKLVLRFSDFGKAM

FAM20A

221

Q96MK3
LMELGLTAAKFARKR

SMG1

1421

Q96Q15
HKLHRMLSFGFTDKV

MORC4

96

Q8TE76
VSAILMAFGKERKSL

PKD1L3

1671

Q7Z443
AGKTTLLHMLKDDRL

SAR1A

36

Q9NR31
IKLIKDMAAGHLSEA

MYCBP2

4176

O75592
IMHLKHLIKFRTSEA

WDR17

781

Q8IZU2
KLVHFFMSRGQLKEA

WDR17

891

Q8IZU2
VAAFARHMLEKKIGV

SPTLC3

471

Q9NUV7
GTVLKMTDRSHRQKL

STIM1

176

Q13586
LILAVKLETHASMRK

RANBP6

101

O60518
HKGSLLRLTAFMEKY

STARD8

526

Q92502
YGKDLTSVMRLLSKH

SPTBN1

666

Q01082
DGVRKSVHKVFASML

GTF3C3

76

Q9Y5Q9
TILGAMKDVVKHRTS

ABCB7

646

O75027
GTRMAALKAKYTLLH

CCDC146

61

Q8IYE0
RVKNFHSGLLLSRVM

CFAP210

151

Q0VFZ6
AILHLFSADMKKVGI

CLHC1

496

Q8NHS4
SLMRHAKGLDQDTFK

C17orf64

36

Q86WR6
LLKKHILVMSFIGHD

RIOK3

351

O14730
HRKSVKKGFDFTLMV

SEPTIN1

21

Q8WYJ6
KLHISMLALEKESGV

WDR47

26

O94967
KEYLSLGALKMHIRS

SNAI1

161

O95863
TRKMLDHIAREVGLK

ZFHX4

2586

Q86UP3
MALVKHSVLLSASRK

WEE1

561

P30291
KLLSKMAGRSVAHLF

TNFAIP8L2

16

Q6P589
GKLFSNMLILKTHEE

ZFHX2

1486

Q9C0A1
GSQILMDLSHKAVKR

NEURL1

71

O76050
KILTHVAEMQGKSAR

SUN2

491

Q9UH99
IRLFKKSKEIGLQMH

SRGAP3

136

O43295
CLLHGMTVVIRKKFS

SLC27A4

301

Q6P1M0
HLEFTMSKARQLEGK

SPIDR

531

Q14159
MLALGIDFATRKIAK

RBP7

21

Q96R05
GVLRKLAKVSHMTSD

STX10

211

O60499
TLSAGLKFHERMGTK

ZDBF2

281

Q9HCK1
LKFHERMGTKGSLRV

ZDBF2

286

Q9HCK1
IFKRIGFLNKHAMTV

ZNF654

756

Q8IZM8
DAMLRALLGSKHKVS

TNNI1

121

P19237
ALLGSKHKVSMDLRA

TNNI1

126

P19237
KHRKSLLLTDISMEN

NF1

2456

P21359
TAPLMFSRRHSLKKV

TEX13C

681

A0A0J9YWL9
SLLKLKMVQVVFRHG

ACP6

46

Q9NPH0
SKMIAKAFSKRHELL

SMO

566

Q99835
GKSHIEKLIFRMAAP

PLEKHH1

1296

Q9ULM0
LDLSETFKFMKRHTL

ZNF844

541

Q08AG5
ALSSEFVMKDLLHKG

ZNF347

91

Q96SE7
KVDSLLHGTFSAKML

TRMT6

261

Q9UJA5
LHFLNLEGMKKSRSL

ZGRF1

1036

Q86YA3
KGFTVKSMLIIHQRT

ZNF432

436

O94892
AFSTKGSLKVHMRLH

ZNF236

1231

Q9UL36
LDRLKVFMQVHASKT

SLC25A23

206

Q9BV35
IHRESLAMKKISAEL

ZBED9

1001

Q6R2W3
HTMGRALLSLQKFKE

TTC23

141

Q5W5X9
HLKDSEGMGRTKFLS

TTC23

301

Q5W5X9
TKELKDTMRTSHGLR

TASOR2

1931

Q5VWN6
HMKAKGAALSVDIRT

UGT2B15

406

P54855
ALKHMKTSVHSRLGI

UGGT2

761

Q9NYU1
GHRTSKIMRFVDKIT

TEX2

981

Q8IWB9
AGKTTLLHMLKDDRL

SAR1B

36

Q9Y6B6
KKGMFASTHLILKER

TOPBP1

686

Q92547
LEATNGMKLHFSKTL

ZP2

306

Q05996
KEMKGSIRHLRLTEA

THAP11

276

Q96EK4
CMKRKELITVFHIGS

TRPM7

371

Q96QT4
KLLIENGVSMHKFLT

TRPM7

456

Q96QT4
HMKAKGAALSVDIRT

UGT2B17

406

O75795
GRLLKDMLPFTKHSA

WDR64

801

B1ANS9
LPAMLHKLKVRAESF

KDM5C

756

P41229
AFLRTHVPKDMKLVL

LDAH

121

Q9H6V9
FFSICGKHVTLKMLL

NALCN

1311

Q8IZF0
SKSLKLIISMTLHDR

MYO9B

796

Q13459
HKMIVSEKGLHSLIF

MYOT

296

Q9UBF9