Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH11

1.75e-0418222GO:0008569
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO10 DNAH3 DNAH11

2.85e-04118223GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH11

4.30e-0428222GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH11

7.54e-0437222GO:0045505
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DNAH11

2.67e-0370222GO:0003777
GeneOntologyCellularComponentdynein complex

CCDC65 DYNC2LI1 DNAH3 DNAH11

2.81e-0754224GO:0030286
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

CCDC65 DYNC2LI1 BLOC1S5 DNAH3 DNAH11

1.66e-05317225GO:0032838
GeneOntologyCellularComponentmicrotubule associated complex

CCDC65 DYNC2LI1 DNAH3 DNAH11

2.23e-05161224GO:0005875
GeneOntologyCellularComponentcytoplasmic region

CCDC65 DYNC2LI1 BLOC1S5 DNAH3 DNAH11

3.05e-05360225GO:0099568
GeneOntologyCellularComponentaxoneme

CCDC65 DYNC2LI1 DNAH3 DNAH11

5.94e-05207224GO:0005930
GeneOntologyCellularComponentciliary plasm

CCDC65 DYNC2LI1 DNAH3 DNAH11

6.05e-05208224GO:0097014
GeneOntologyCellularComponenttriglyceride-rich plasma lipoprotein particle

VLDLR APOL1

2.88e-0424222GO:0034385
GeneOntologyCellularComponentvery-low-density lipoprotein particle

VLDLR APOL1

2.88e-0424222GO:0034361
GeneOntologyCellularComponentaxonemal dynein complex

CCDC65 DNAH3

3.13e-0425222GO:0005858
GeneOntologyCellularComponentmotile cilium

CCDC65 DYNC2LI1 DNAH3 DNAH11

4.70e-04355224GO:0031514
GeneOntologyCellularComponentlipoprotein particle

VLDLR APOL1

9.74e-0444222GO:1990777
GeneOntologyCellularComponentplasma lipoprotein particle

VLDLR APOL1

9.74e-0444222GO:0034358
GeneOntologyCellularComponentprotein-lipid complex

VLDLR APOL1

1.11e-0347222GO:0032994
GeneOntologyCellularComponentclathrin-coated pit

VLDLR SGIP1

3.18e-0380222GO:0005905
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH11

1.09e-0414212IPR011704
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH11

1.09e-0414212IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH11

1.09e-0414212IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH11

1.09e-0414212IPR013602
DomainDHC_N2

DNAH3 DNAH11

1.09e-0414212PF08393
DomainMT

DNAH3 DNAH11

1.09e-0414212PF12777
DomainAAA_8

DNAH3 DNAH11

1.09e-0414212PF12780
DomainAAA_5

DNAH3 DNAH11

1.09e-0414212PF07728
DomainDHC_fam

DNAH3 DNAH11

1.25e-0415212IPR026983
DomainDynein_heavy_dom

DNAH3 DNAH11

1.25e-0415212IPR004273
DomainDynein_heavy

DNAH3 DNAH11

1.25e-0415212PF03028
DomainSEA

MUC3A TMPRSS11B

3.00e-0423212PS50024
DomainSEA_dom

MUC3A TMPRSS11B

3.00e-0423212IPR000082
DomainARM-type_fold

PIK3CB HEATR1 VPS35

6.19e-03339213IPR016024
DomainAAA+_ATPase

DNAH3 DNAH11

1.13e-02144212IPR003593
DomainAAA

DNAH3 DNAH11

1.13e-02144212SM00382
DomainP-loop_NTPase

DYNC2LI1 MYO10 DNAH3 DNAH11

1.36e-02848214IPR027417
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH3 DNAH11

8.01e-0672229256245
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH11

3.46e-05142229373155
Pubmed

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.

DYNC2LI1 DNAH11

7.21e-052022217251353
Pubmed

Primary Ciliary Dyskinesia

CCDC65 DNAH11

1.87e-043222220301301
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

DYNC2LI1 DNAH11

2.94e-044022232317081
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

CACNA1A MUC3A HEATR1 DNAH11

3.66e-0455222410737800
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

AHR PIK3CB VLDLR

4.16e-0423322332290105
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

CACNA1A DNAH3 DNAH11

4.16e-0423322337704626
CytobandEnsembl 112 genes in cytogenetic band chr15q25

ADAMTSL3 HYKK

2.66e-03160222chr15q25
CytobandEnsembl 112 genes in cytogenetic band chr1p31

DEPDC1 SGIP1

5.13e-03224222chr1p31
GeneFamilyDyneins, axonemal

DNAH3 DNAH11

1.26e-0417182536
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 PIK3CB SGIP1 DNAH11

1.60e-06177224da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 PIK3CB SGIP1 DNAH11

1.87e-06184224da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 PIK3CB SGIP1 DNAH11

2.08e-06189224904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC65 DYNC2LI1 DNAH3 DNAH11

2.40e-0619622427b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC65 DYNC2LI1 DNAH3 DNAH11

2.50e-06198224ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTSL3 DEPDC1 SGIP1

3.65e-0513222302491930097b75aaeedab9e8200711b0dc610944
ToppCellPND07-28-samps-Mesenchymal-Pericyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ADAMTSL3 HYKK SGIP1

5.34e-051502235b111ec11a642d63fafa7e1422e36f81a2776531
ToppCellPND07-28-samps-Mesenchymal-Pericyte-pericyte_F|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ADAMTSL3 HYKK SGIP1

5.34e-051502232d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CCDC65 DNAH3 DNAH11

7.34e-0516722326cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AHR CACNA1A PIK3CB

8.01e-05172223490745024730df6357f6c2b81d7a64e21557c0d5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 SGIP1 DNAH11

8.58e-05176223327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 SGIP1 DNAH11

8.72e-05177223a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 SGIP1 DNAH11

8.72e-051772233645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CCDC65 DNAH3 DNAH11

8.72e-05177223c38138fb5ad9766c2d240811210c854338cd612e
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

8.87e-05178223185b44700f06ec58b3c09c80520502166c965fd6
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC65 DNAH3 DNAH11

8.87e-05178223255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTSL3 MYO10 SGIP1

9.02e-05179223dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

9.32e-05181223451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 SGIP1 DNAH11

9.32e-051812236a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 PIK3CB SGIP1

9.32e-05181223071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 PIK3CB SGIP1

9.63e-05183223738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

9.63e-05183223fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 PIK3CB SGIP1

9.63e-0518322392fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 SGIP1 DNAH11

9.63e-05183223cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

9.94e-05185223a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

CCDC65 DNAH3 DNAH11

9.94e-051852230998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellP28-Epithelial-airway_epithelial_cell-club_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCDC65 DNAH3 DNAH11

1.01e-04186223a26811481668fa25c48a064a56c198685693ad8d
ToppCellP28-Epithelial-airway_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CCDC65 DNAH3 DNAH11

1.01e-04186223df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC65 DNAH3 DNAH11

1.01e-04186223f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC65 DNAH3 DNAH11

1.01e-0418622376033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTSL3 MYO10 SGIP1

1.01e-04186223888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC65 DNAH3 DNAH11

1.01e-0418622385787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTSL3 MYO10 DNAH11

1.03e-04187223ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A MYO10 VLDLR

1.03e-04187223cfdc1585c80d2bb475d9145395fb50a88c53f838
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

1.03e-04187223a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

1.03e-0418722386250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

1.04e-04188223ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A MYO10 VLDLR

1.04e-041882232b630b0609d4ac61338d6533cb7893cfe1241e44
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DYNC2LI1 SGIP1 DNAH11

1.04e-0418822363a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

CCDC65 DNAH3 DNAH11

1.04e-041882236833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CCDC65 DNAH3 DNAH11

1.04e-04188223606907c865bd2f11bb6474932716550f7723d858
ToppCellMulticiliated|World / shred by cell class for nasal brushing

CCDC65 DNAH3 DNAH11

1.06e-0418922334b110aef839376228c5a403a6b5047a945f472b
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

1.06e-04189223d7ed96add29f219183c802895fbff519b627f635
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC65 DNAH3 DNAH11

1.06e-0418922302c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC65 DNAH3 DNAH11

1.06e-04189223a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC65 DNAH3 DNAH11

1.06e-04189223dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC65 DNAH3 DNAH11

1.06e-04189223164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTSL3 MYO10 SGIP1

1.08e-041902234eb92aef1ee868f4537483d19014d947b7684612
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC65 DNAH3 DNAH11

1.08e-04190223833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTSL3 MYO10 SGIP1

1.08e-041902237be4341e2909101d756f14031c21e705eb45e69a
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

CCDC65 DNAH3 DNAH11

1.08e-04190223426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

CCDC65 DNAH3 DNAH11

1.08e-041902237031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTSL3 ST3GAL2 SGIP1

1.08e-04190223951e067d14412db67dc3babcdf61e41717d7b429
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL3 SGIP1 DNAH11

1.08e-041902235681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC65 DNAH3 DNAH11

1.08e-041902239ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC65 DNAH3 DNAH11

1.08e-04190223a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A MYO10 VLDLR

1.08e-041902237179f980f895d3e5b839b5ae26b5c991787bfe3a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A MYO10 VLDLR

1.08e-04190223600b9674197f743dea1d19d3df0fc993b6e6aa25
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTSL3 MYO10 SGIP1

1.09e-04191223716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellP07-Mesenchymal-developing_mesenchymal_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTSL3 DEPDC1 SGIP1

1.09e-04191223ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCellASK428-Epithelial-Ciliated|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC65 DNAH3 DNAH11

1.09e-041912230c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTSL3 MYO10 SGIP1

1.09e-041912231626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A MYO10 VLDLR

1.11e-04192223c5f77c2103841505d13e09173549811312ef2f01
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.11e-041922231b6cac8156e608061e1405e36e18d185b6fa8f6f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A MYO10 VLDLR

1.11e-0419222332927ef3b93e0497e9bbe63c2754da03cf178202
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A MYO10 VLDLR

1.11e-04192223e981162f387a31111c0ae8355dbe9db5785c4838
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC65 DNAH3 DNAH11

1.11e-04192223be592e661367affced9ebe80849b466e6adb3a34
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1A MYO10 VLDLR

1.11e-041922233b0a52e4e77ae4539a034dcb419773b8e2aa5d51
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC65 DNAH3 DNAH11

1.13e-041932230b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.13e-04193223e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTSL3 MYO10 SGIP1

1.13e-04193223b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.14e-041942233cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC65 DNAH3 DNAH11

1.14e-041942231ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

ADAMTSL3 MYO10 SGIP1

1.14e-041942233892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC65 DNAH3 DNAH11

1.14e-041942235aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC65 DNAH3 DNAH11

1.14e-04194223c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellwk_15-18-Epithelial-Proximal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CCDC65 DNAH3 DNAH11

1.14e-04194223b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC65 DNAH3 DNAH11

1.16e-041952233486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC65 DNAH3 DNAH11

1.16e-04195223e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.16e-0419522393b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.16e-041952236365e3893e38231090ec2dbef010dec71dea3d07
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC65 DNAH3 DNAH11

1.16e-0419522307a6bcef6af93ed87df455dee624037cb75e011a
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CCDC65 DNAH3 DNAH11

1.16e-04195223cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.16e-04195223581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.16e-04195223db4270c135c392ed443670981656e3cd5b95939d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.16e-04195223d211a836cf711fdb91b10d512f09d462be937cc5
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC65 DNAH3 DNAH11

1.16e-0419522334e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.16e-041952230e763f36786515698b593e5c93f6a56619c1242d
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

CCDC65 DNAH3 DNAH11

1.18e-04196223de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC65 DNAH3 DNAH11

1.18e-04196223d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC65 DNAH3 DNAH11

1.18e-04196223ca56311edc6788e032e7635fa69b1e07035202b5
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC65 DNAH3 DNAH11

1.18e-04196223686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CCDC65 DNAH3 DNAH11

1.18e-041962231cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC65 DNAH3 DNAH11

1.18e-0419622369f5081e06d84ec1d9695762df801a9d0df1984b
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCDC65 DNAH3 DNAH11

1.18e-0419622367aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.20e-041972233bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.20e-0419722387db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC65 DNAH3 DNAH11

1.20e-04197223d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC65 DNAH3 DNAH11

1.20e-041972236865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC65 DNAH3 DNAH11

1.20e-0419722391637bdeab85024b5a02d1066f76cb803a2d6420
ComputationalGenes in the cancer module 236.

VLDLR APOL1

3.13e-0418162MODULE_236
Drugmonorden

AHR VLDLR

6.91e-0513222ctd:C035359
DrugH 17

AHR CACNA1A

1.20e-0417222CID000476867
Drugoctylmethoxycinnamate

AHR CACNA1A VLDLR

3.15e-04139223ctd:C118580
Drugherbimycin

AHR VLDLR

4.07e-0431222ctd:C020754
Druglavendustin A

AHR CACNA1A PIK3CB

5.77e-04171223CID000003894
Drug15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A

PIK3CB DNAH3 ZNF84

6.92e-041822231231_DN
DrugBiliton

DNAH3 DNAH11

7.14e-0441222CID000002974
Drugorthovanadate

MYO10 PIK3CB DNAH3 DNAH11

7.32e-04435224CID000061672
DrugICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A_EA

AHR DYNC2LI1 ST3GAL2

7.48e-041872231043_UP
DrugFk 888

AHR CACNA1A

7.50e-0442222CID000107967
Drug17-DMAG; Down 200; 0.1uM; PC3; HT_HG-U133A

PIK3CB ST3GAL2 ZNF84

7.60e-041882231213_DN
DrugFluticasone propionate [80474-14-2]; Down 200; 8uM; HL60; HT_HG-U133A

MYO10 DNAH3 TPD52L1

7.72e-041892232928_DN
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A

AHR DYNC2LI1 TPD52L1

7.96e-041912231561_UP
DrugDiltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; PC3; HT_HG-U133A

PIK3CB ST3GAL2 TPD52L1

7.96e-041912236710_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

AHR DYNC2LI1 ST3GAL2

7.96e-04191223998_DN
Druganthraflavic acid

AHR APOL1

8.23e-0444222CID000006776
DrugAcetopromazine maleate salt [3598-37-6]; Down 200; 9uM; MCF7; HT_HG-U133A

AHR MYO10 ST3GAL2

8.32e-041942236832_DN
DrugFamprofazone [22881-35-2]; Down 200; 10.6uM; PC3; HT_HG-U133A

MYO10 PIK3CB TPD52L1

8.32e-041942234309_DN
DrugRapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A

MYO10 DNAH3 ST3GAL2

8.45e-041952236180_DN
DrugTiapride hydrochloride [51012-33-0]; Down 200; 11uM; MCF7; HT_HG-U133A

AHR MYO10 ST3GAL2

8.45e-041952234686_DN
DrugBenzbromarone [3562-84-3]; Down 200; 9.4uM; PC3; HT_HG-U133A

CACNA1A DYNC2LI1 TPD52L1

8.58e-041962236669_DN
DrugMidecamycin [35457-80-8]; Down 200; 5uM; MCF7; HT_HG-U133A

DYNC2LI1 MYO10 PIK3CB

8.70e-041972231526_DN
Drugaspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A_EA

DYNC2LI1 ST3GAL2 ZNF84

8.70e-041972231042_UP
DrugLorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A

DYNC2LI1 MYO10 VLDLR

8.70e-041972236456_DN
DrugEthacrynic acid [58-54-8]; Down 200; 13.2uM; PC3; HT_HG-U133A

PIK3CB DNAH3 ZNF84

8.83e-041982235742_DN
DrugUrapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; PC3; HT_HG-U133A

PIK3CB DNAH3 ST3GAL2

8.83e-041982236696_DN
DrugNetilmicin sulfate [56931-57-2]; Down 200; 2.8uM; PC3; HT_HG-U133A

DYNC2LI1 DNAH3 TPD52L1

8.83e-041982237302_DN
DrugIsoetharine mesylate salt [7279-75-6]; Up 200; 12uM; MCF7; HT_HG-U133A

CACNA1A VLDLR ST3GAL2

8.96e-041992233451_UP
DiseaseWeight Gain

AHR MYO10 DNAH11

5.89e-05102223C0043094
DiseaseDyslipidemias

AHR DNAH11

1.45e-0424222C0242339
DiseaseDyslipoproteinemias

AHR DNAH11

1.45e-0424222C0598784
DiseasePrimary ciliary dyskinesia

CCDC65 DNAH11

3.29e-0436222cv:C0008780
Diseasekynurenine measurement

AHR DNAH11

3.87e-0439222EFO_0008529
Diseaseglioblastoma (is_marker_for)

PIK3CB HEATR1

4.93e-0444222DOID:3068 (is_marker_for)
DiseasePrimary Ciliary Dyskinesia

CCDC65 DNAH11

5.62e-0447222C4551720
Diseasefrontal fibrosing alopecia

CACNA1A MYO10

5.86e-0448222EFO_0009855
Diseasesquamous cell carcinoma

AHR DNAH11

1.14e-0367222EFO_0000707
DiseaseNon-alcoholic Fatty Liver Disease

AHR VLDLR

1.24e-0370222C0400966
DiseaseNonalcoholic Steatohepatitis

AHR VLDLR

1.24e-0370222C3241937
Diseasenon-high density lipoprotein cholesterol measurement

AHR CACNA1A VLDLR DNAH11

1.75e-03713224EFO_0005689
Diseasesunburn

AHR SGIP1

2.32e-0396222EFO_0003958

Protein segments in the cluster

PeptideGeneStartEntry
KMKHMQVNGMFENWN

AHR

641

P35869
HMPQNKQSFQYRMWQ

CACNA1A

1546

O00555
ASEKQHMLQWDNFMK

BLOC1S5

136

Q8TDH9
HMLQWDNFMKEQPNK

BLOC1S5

141

Q8TDH9
MWNDLKNMNLEEKHF

CCDC65

196

Q8IXS2
KNMPFTSGNMKWAQQ

DNAH11

626

Q96DT5
MRQKIWNNMPKDHPD

DYNC2LI1

156

Q8TCX1
KTFWNQMQKIFADMQ

MUC3A

3051

Q02505
MKCLANWPRSNDMNN

DEPDC1

251

Q5TB30
DKWRKFQGMNQEQAM

MYO10

1926

Q9HD67
GWKHLQQMFDMGQKA

HYKK

341

A2RU49
MIDPHGQANKWIKNM

DNAH3

3081

Q8TD57
QMIMKDKNWHDKGQQ

APOL1

121

O14791
KQIEKNWKNHMGPFM

HEATR1

1831

Q9H583
NWKNHMGPFMSILQE

HEATR1

1836

Q9H583
PMSNNVKMKWQFEHT

MT-ND2

306

P03891
WWMMLQPQFKSHNTN

ST3GAL2

111

Q16842
KQMLWKQVHNYPMFN

PIK3CB

56

P42338
HQMLKNNMASWNAVP

TMPRSS11B

136

Q86T26
NTKEFWVNMPNLMTH

SGIP1

641

Q9BQI5
NFAEMNKLWVRMQHQ

VPS35

186

Q96QK1
GNMMWHQDNQDKLKI

ZNF84

86

P51523
MNELKQNFSKSWHDM

TPD52L1

76

Q16890
NWQHKNMKSMNFDNP

VLDLR

821

P98155
HKMRQMWNNKNDLYL

ADAMTSL3

1031

P82987