Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	1.50e-05	12	78	3	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A5	1.50e-05	12	78	3	IPR027970
Domain	SINA-like	ZSWIM9 SIAH2	1.03e-04	4	78	2	IPR004162
Domain	PH	ANLN OSBPL3 GAB4 OSBPL7 TRIOBP ARHGAP21	3.92e-04	229	78	6	PF00169
Domain	PH	ANLN OSBPL3 GAB4 OSBPL7 TRIOBP ARHGAP21	1.08e-03	278	78	6	SM00233
Domain	PH_DOMAIN	ANLN OSBPL3 GAB4 OSBPL7 TRIOBP ARHGAP21	1.10e-03	279	78	6	PS50003
Domain	Oxysterol-bd	OSBPL3 OSBPL7	1.11e-03	12	78	2	IPR000648
Domain	Oxysterol-bd_CS	OSBPL3 OSBPL7	1.11e-03	12	78	2	IPR018494
Domain	Oxysterol_BP	OSBPL3 OSBPL7	1.11e-03	12	78	2	PF01237
Domain	OSBP	OSBPL3 OSBPL7	1.11e-03	12	78	2	PS01013
Domain	PH_domain	ANLN OSBPL3 GAB4 OSBPL7 TRIOBP ARHGAP21	1.12e-03	280	78	6	IPR001849
Domain	-	MAPK8IP1 ANLN OSBPL3 GAB4 OSBPL7 TRIOBP ARHGAP21	1.23e-03	391	78	7	2.30.29.30
Domain	PH_dom-like	MAPK8IP1 ANLN OSBPL3 GAB4 OSBPL7 TRIOBP ARHGAP21	2.01e-03	426	78	7	IPR011993
Domain	cEGF	FBLN2 LRP1	5.24e-03	26	78	2	IPR026823
Domain	cEGF	FBLN2 LRP1	5.24e-03	26	78	2	PF12662
Domain	DUSP	EPM2A SSH2	7.40e-03	31	78	2	IPR024950
Domain	EGF_Ca-bd_CS	EYS FBLN2 LRP1	7.80e-03	97	78	3	IPR018097
Domain	EGF_CA	EYS FBLN2 LRP1	8.25e-03	99	78	3	PS01187
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A5	2.42e-07	6	81	3	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A5	2.42e-07	6	81	3	25930072
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ALMS1 ZNF473 OSBPL3 COBLL1 RNF213 SSH2 FANCM WNK1 MED12	2.27e-06	493	81	9	15368895
Pubmed	CBX2-mediated suppression of SIAH2 triggers WNK1 accumulations to promote glycolysis in hepatocellular carcinoma.	SIAH2 WNK1	5.36e-06	2	81	2	36780970
Pubmed	Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway.	MAPK8IP1 MAP3K13	1.60e-05	3	81	2	11726277
Pubmed	The Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.	SIAH2 FOXA2	1.60e-05	3	81	2	21037926
Pubmed	Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia.	COBLL1 SH3BP1	1.60e-05	3	81	2	35352878
Pubmed	Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: the expression and intracellular localization of ORP3, ORP6, and ORP7.	OSBPL3 OSBPL7	1.60e-05	3	81	2	14593528
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A5	2.38e-05	24	81	3	32212159
Pubmed	Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.	FOXA2 MEOX1	3.20e-05	4	81	2	7958910
Pubmed	Mutational analysis of FANCL, FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer predisposition.	BRCA2 FANCM	3.20e-05	4	81	2	19737859
Pubmed	Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors.	SIAH2 FOXA2	5.33e-05	5	81	2	20609350
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ALMS1 BRCA2 LRP1 CHD6 ARHGAP21 MED12 NPAT	5.58e-05	418	81	7	34709266
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	CENPT LRP1 IREB2 RFTN2 MPHOSPH9 NUTF2	7.81e-05	303	81	6	25056061
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	ALMS1 PKD1 RNF213 CACNA1H SSH2	7.84e-05	187	81	5	26460568
Pubmed	A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.	SMARCB1 MYB	7.99e-05	6	81	2	10619021
Pubmed	Tulp3 Is a Ciliary Trafficking Gene that Regulates Polycystic Kidney Disease.	PKD1 TULP3	7.99e-05	6	81	2	30799240
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ALMS1 PER2 WNK1 ZNF646	1.05e-04	104	81	4	9205841
Pubmed	fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation.	FOXA2 MEOX1	1.12e-04	7	81	2	8001822
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	C2CD3 CENPT ALMS1 ANLN CHD6 MPHOSPH9 WNK1 MED12	1.31e-04	645	81	8	25281560
Pubmed	The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.	OSBPL3 OSBPL7	1.49e-04	8	81	2	17428193
Pubmed	Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.	CACNA1H FOXA2	1.49e-04	8	81	2	34478646
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	C2CD3 ALMS1 ANLN OSBPL3 COBLL1 MPHOSPH9 SSH2 WNK1 ARHGAP21	1.78e-04	861	81	9	36931259
Pubmed	Requirement for Lim1 in head-organizer function.	FOXA2 MEOX1	2.38e-04	10	81	2	7700351
Pubmed	Otx2 and HNF3beta genetically interact in anterior patterning.	FOXA2 MEOX1	2.38e-04	10	81	2	11291866
Pubmed	Importin alpha/beta mediates nuclear transport of a mammalian circadian clock component, mCRY2, together with mPER2, through a bipartite nuclear localization signal.	PER2 NUTF2	2.38e-04	10	81	2	15689618
Pubmed	Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation.	FOXA2 MEOX1	2.91e-04	11	81	2	10518210
Pubmed	The OSBP-related protein family in humans.	OSBPL3 OSBPL7	2.91e-04	11	81	2	11483621
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ALMS1 ASB6 ANLN TMEM131L RNF213 CHD6 MPHOSPH9 WNK1	3.11e-04	733	81	8	34672954
Pubmed	A family of 12 human genes containing oxysterol-binding domains.	OSBPL3 OSBPL7	3.48e-04	12	81	2	11735225
Pubmed	Pten regulates collective cell migration during specification of the anterior-posterior axis of the mouse embryo.	FOXA2 MEOX1	3.48e-04	12	81	2	22342906
Pubmed	Loss of late primitive streak mesoderm and interruption of left-right morphogenesis in the Ednrb(s-1Acrg) mutant mouse.	FOXA2 MEOX1	3.48e-04	12	81	2	10964471
Pubmed	WNK1 regulates uterine homeostasis and its ability to support pregnancy.	FOXA2 WNK1	3.48e-04	12	81	2	33048843
Pubmed	STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo.	FOXA2 MEOX1	3.48e-04	12	81	2	29203676
Pubmed	Fgf10 and Sox9 are essential for the establishment of distal progenitor cells during mouse salivary gland development.	ETV5 MYB	3.48e-04	12	81	2	28506998
Pubmed	An oxysterol-binding protein family identified in the mouse.	OSBPL3 OSBPL7	3.48e-04	12	81	2	12215260
Pubmed	Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK).	FOXA2 MEOX1	3.48e-04	12	81	2	11290295
Pubmed	Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6.	FOXA2 MEOX1	4.11e-04	13	81	2	9490412
Pubmed	NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction.	BRCA2 CHD6	4.11e-04	13	81	2	28416489
Pubmed	The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability.	CENPT FANCM	4.11e-04	13	81	2	24699063
Pubmed	Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo.	FOXA2 MEOX1	4.11e-04	13	81	2	12117810
Pubmed	Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.	FOXA2 MEOX1	4.11e-04	13	81	2	18268105
Pubmed	Tulp3 is a critical repressor of mouse hedgehog signaling.	FOXA2 TULP3	4.11e-04	13	81	2	19334287
Pubmed	A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain.	FOXA2 MEOX1	4.11e-04	13	81	2	8565836
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	ALMS1 BRCA2 YJU2B MPHOSPH9	4.49e-04	152	81	4	38360978
Pubmed	Genetic rescue of segmentation defect in MesP2-deficient mice by MesP1 gene replacement.	FOXA2 MEOX1	4.79e-04	14	81	2	9739106
Pubmed	The amn gene product is required in extraembryonic tissues for the generation of middle primitive streak derivatives.	FOXA2 MEOX1	4.79e-04	14	81	2	9851841
Pubmed	Zic3 is critical for early embryonic patterning during gastrulation.	FOXA2 MEOX1	4.79e-04	14	81	2	16397896
Pubmed	HNF-3 beta is essential for node and notochord formation in mouse development.	FOXA2 MEOX1	5.52e-04	15	81	2	8069909
Pubmed	Goosecoid and HNF-3beta genetically interact to regulate neural tube patterning during mouse embryogenesis.	FOXA2 MEOX1	5.52e-04	15	81	2	9226455
Pubmed	Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos.	FOXA2 MEOX1	5.52e-04	15	81	2	9334279
Pubmed	Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease.	MAPK8IP1 LRP1	5.52e-04	15	81	2	20205790
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	SMARCB1 INO80D MED12	5.71e-04	69	81	3	28481362
Pubmed	The zinc-finger protein CNBP is required for forebrain formation in the mouse.	FOXA2 MEOX1	6.29e-04	16	81	2	12588852
Pubmed	Bmpr1a is required for proper migration of the AVE through regulation of Dkk1 expression in the pre-streak mouse embryo.	FOXA2 MEOX1	6.29e-04	16	81	2	20211162
Pubmed	Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks.	FOXA2 MEOX1	6.29e-04	16	81	2	12431380
Pubmed	The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling.	FOXA2 TULP3	6.29e-04	16	81	2	31964774
Pubmed	Murine fibroblast growth factor receptor 1alpha isoforms mediate node regression and are essential for posterior mesoderm development.	FOXA2 MEOX1	6.29e-04	16	81	2	10191046
Pubmed	Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.	BRCA2 FANCM	6.29e-04	16	81	2	27760317
Pubmed	Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival.	FOXA2 MEOX1	6.29e-04	16	81	2	18332127
Pubmed	Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching.	FOXA2 MEOX1	7.12e-04	17	81	2	16831833
Pubmed	TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration.	FOXA2 MEOX1	7.12e-04	17	81	2	35950911
Pubmed	Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality.	FOXA2 MEOX1	7.12e-04	17	81	2	11884616
Pubmed	Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo.	FOXA2 MEOX1	8.00e-04	18	81	2	17490632
Pubmed	Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo.	FOXA2 MEOX1	8.00e-04	18	81	2	15084457
Pubmed	Gata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb Development.	ETV5 TULP3	8.00e-04	18	81	2	27352137
Pubmed	C2cd3 is required for cilia formation and Hedgehog signaling in mouse.	C2CD3 FOXA2	8.00e-04	18	81	2	19004860
Pubmed	Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.	MAPK8IP1 LRP1	8.00e-04	18	81	2	10827173
Pubmed	p120-catenin regulates WNT signaling and EMT in the mouse embryo.	FOXA2 MEOX1	8.93e-04	19	81	2	31371508
Pubmed	An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.	MED12 MYB	8.93e-04	19	81	2	16799563
Pubmed	The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo.	ETV5 MEOX1	8.93e-04	19	81	2	17507402
Pubmed	BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites.	FOXA2 MEOX1	9.91e-04	20	81	2	16943278
Pubmed	Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo.	FOXA2 MEOX1	9.91e-04	20	81	2	9790191
Pubmed	TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development.	ETV5 MEOX1	9.91e-04	20	81	2	36542062
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FAM114A1 ALMS1 TNKS2 WNK1 ARHGAP21 TULP3	1.09e-03	497	81	6	23414517
Pubmed	Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1.	FOXA2 MEOX1	1.09e-03	21	81	2	12471260
Pubmed	ETAA1 acts at stalled replication forks to maintain genome integrity.	BRCA2 FANCM	1.09e-03	21	81	2	27723720
Pubmed	Ureteric morphogenesis requires Fgfr1 and Fgfr2/Frs2α signaling in the metanephric mesenchyme.	ETV5 MYB	1.09e-03	21	81	2	22282599
Pubmed	Frs2α and Shp2 signal independently of Gab to mediate FGF signaling in lens development.	GAB4 ETV5	1.09e-03	21	81	2	24284065
Pubmed	Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion.	ETV5 MYB	1.09e-03	21	81	2	24603431
Pubmed	Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo.	FOXA2 MEOX1	1.09e-03	21	81	2	18701545
Pubmed	Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.	PKD1 FOXA2	1.09e-03	21	81	2	16291790
Pubmed	Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.	YAE1 IREB2 WNK1	1.20e-03	89	81	3	23891004
Pubmed	Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.	FOXA2 TULP3	1.20e-03	22	81	2	19223390
Pubmed	Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.	FOXA2 MEOX1	1.20e-03	22	81	2	9136933
Pubmed	E3 ubiquitin ligase RFWD2 controls lung branching through protein-level regulation of ETV transcription factors.	ETV5 FOXA2	1.20e-03	22	81	2	27335464
Pubmed	Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney.	ETV5 MYB	1.31e-03	23	81	2	21035938
Pubmed	Fanconi Anemia	BRCA2 FANCM	1.31e-03	23	81	2	20301575
Pubmed	Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo.	FOXA2 MEOX1	1.43e-03	24	81	2	21693517
Pubmed	MesP1 and MesP2 are essential for the development of cardiac mesoderm.	FOXA2 MEOX1	1.43e-03	24	81	2	10887078
Pubmed	Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis.	FOXA2 MEOX1	1.43e-03	24	81	2	37414952
Pubmed	Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.	ZSWIM9 ANLN SIGLEC11	1.44e-03	95	81	3	24029230
Pubmed	Discovery and refinement of loci associated with lipid levels.	BRCA2 COBLL1 OSBPL7 LRP1	1.52e-03	211	81	4	24097068
Pubmed	Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.	MAPK8IP1 FOXA2	1.55e-03	25	81	2	18324732
Pubmed	Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.	PKD1 TULP3	1.55e-03	25	81	2	28154160
Pubmed	Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation.	FOXA2 MEOX1	1.55e-03	25	81	2	19056886
Pubmed	Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation.	FBLN2 MEOX1	1.68e-03	26	81	2	22130515
Pubmed	Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.	FOXA2 MEOX1	1.68e-03	26	81	2	28087629
Pubmed	The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium.	ETV5 FOXA2	1.68e-03	26	81	2	26809587
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	C2CD3 ALMS1 MPHOSPH9	1.72e-03	101	81	3	24613305
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	8.55e-05	8	81	2	chr9q12
Cytoband	19q13.33	ZSWIM9 ZNF473 SIGLEC11	8.96e-04	106	81	3	19q13.33
Cytoband	16q22.1	CENPT PDPR NUTF2	9.97e-04	110	81	3	16q22.1
Cytoband	12p13.3	WNK1 TULP3	1.30e-03	30	81	2	12p13.3
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ANLN OSBPL3 GAB4 OSBPL7 TRIOBP ARHGAP21	7.58e-06	206	42	6	682
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL3 OSBPL7	3.43e-04	12	42	2	670
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	BRCA2 FANCM	9.75e-04	20	42	2	548
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	KIRREL3 SIGLEC11	3.89e-03	40	42	2	592
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	SH3BP1 ARHGAP21	6.01e-03	50	42	2	721
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	CHD6 MYB	6.73e-03	53	42	2	532
Coexpression	GSE22886_NAIVE_VS_MEMORY_TCELL_UP	SNIP1 ALMS1 YJU2B TRIOBP MPHOSPH9 FOXA2 MYB	2.02e-06	194	79	7	M4416
Coexpression	GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN	CENPT BRCA2 ANLN OSBPL3 MPHOSPH9 NUTF2	3.20e-05	200	79	6	M6614
Coexpression	GSE15930_STIM_VS_STIM_AND_IL12_24H_CD8_T_CELL_UP	YJU2B ANLN IREB2 MPHOSPH9 NUTF2 MEOX1	3.20e-05	200	79	6	M3620
Coexpression	GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_UP	YJU2B ANLN SMARCB1 IREB2 CACNA1H MPHOSPH9	3.20e-05	200	79	6	M3648
Disease	nucleus accumbens volume change measurement	MUC16 ITPRID1	3.55e-04	11	76	2	EFO_0021493
Disease	polycystic kidney disease (implicated_via_orthology)	PKD1 TULP3	5.84e-04	14	76	2	DOID:0080322 (implicated_via_orthology)
Disease	Familial Progressive Myoclonic Epilepsy	EPM2A KCNC1	8.68e-04	17	76	2	C0751777
Disease	Atypical Inclusion-Body Disease	EPM2A KCNC1	8.68e-04	17	76	2	C0751776
Disease	Myoclonic Epilepsies, Progressive	EPM2A KCNC1	8.68e-04	17	76	2	C0751778
Disease	Biotin-Responsive Encephalopathy	EPM2A KCNC1	8.68e-04	17	76	2	C0751780
Disease	May-White Syndrome	EPM2A KCNC1	8.68e-04	17	76	2	C0751782
Disease	Dentatorubral-Pallidoluysian Atrophy	EPM2A KCNC1	8.68e-04	17	76	2	C0751781
Disease	Bone marrow hypocellularity	BRCA2 FANCM	9.75e-04	18	76	2	C1855710
Disease	Action Myoclonus-Renal Failure Syndrome	EPM2A KCNC1	9.75e-04	18	76	2	C0751779
Disease	body mass index, high density lipoprotein cholesterol measurement	COBLL1 ETV5	1.09e-03	19	76	2	EFO_0004340, EFO_0004612
Disease	neutrophil measurement	TENT5C TMEM131L SSH2 MYB	1.15e-03	177	76	4	EFO_0803548
Disease	dilated cardiomyopathy	PKD1 SMARCB1	1.21e-03	20	76	2	EFO_0000407
Disease	triglyceride measurement, body fat percentage	KCNU1 COBLL1	1.33e-03	21	76	2	EFO_0004530, EFO_0007800
Disease	unipolar depression, neuroticism measurement	EYS ARHGAP21	1.74e-03	24	76	2	EFO_0003761, EFO_0007660
Disease	Fanconi Anemia	BRCA2 FANCM	1.89e-03	25	76	2	C0015625
Disease	Pancytopenia	BRCA2 FANCM	2.04e-03	26	76	2	C0030312
Disease	obesity (implicated_via_orthology)	ALMS1 ETV5 MED12 TULP3	2.33e-03	215	76	4	DOID:9970 (implicated_via_orthology)
Disease	Miller Dieker syndrome	BRCA2 FANCM	2.54e-03	29	76	2	C0265219

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASDPHSLEEFCSDPH	BARGIN	336	Q6ZT62
AHSVACPSDLVSAHP	EPM2A	236	B3EWF7
CTNTIPTHEGDHSVP	GVINP1	2296	Q7Z2Y8
PHSLEEFCSDPHAVA	SH3BP1	331	Q9Y3L3
HPVHLPSDQDICHES	ALMS1	3486	Q8TCU4
ADPSECPAHESLTHI	ASB6	251	Q9NWX5
HSEDPLTVKDPICAH	COBLL1	666	Q53SF7
SHLHVTEILPTCNPS	NWD2	966	Q9ULI1
TSSQPAESRHLPEEC	RFTN2	436	Q52LD8
VHPACPTDLTVDHSL	IREB2	116	P48200
CLAATPHSLPQEEHI	MEOX1	66	P50221
IDHDPQEIHLECSTS	OOSP2	101	Q86WS3
ENSHSLPPESVCSSV	NPAT	696	Q14207
TGVDAICTHHPDPKS	MUC16	13701	Q8WXI7
TETVSTCDPEHDPPH	EYS	2646	Q5T1H1
CPHTNHSLLVPESSS	ITPRID1	626	Q6ZRS4
TGEQTPPHEHICLSD	MAPK8IP1	201	Q9UQF2
TDEEDCEPPTAHTTH	LRP1	3726	Q07954
CQEHSKESPARSTPH	ANLN	381	Q9NQW6
DHPLPTHQVDHSDRC	FANCM	741	Q8IYD8
HIAEESAPNHSCQSP	CARMIL3	1226	Q8ND23
HSSSCHPQEVQRTVP	C9orf131	841	Q5VYM1
HVEEDTDPNSVHSIP	FBLN2	416	P98095
AHPCTEEKALHPSIQ	PER2	446	O15055
SNEEPVSIPLHACEH	PDPR	251	Q8NCN5
PSVSHPSDHIALVCD	PDE12	591	Q6L8Q7
TDNHVNHSSCPEPVP	MPHOSPH9	901	Q99550
HSITAQDHQPTPDSC	NUTF2	66	P61970
THFPIPQEESCSHEC	MED12	736	Q93074
SECHLSEEDTLPLTH	ETV5	471	P41161
TETHSDTNCPPTIDS	KCNU1	1066	A8MYU2
DSAPVSCLGEHHSTP	MYB	341	P10242
PLCNSSESTSHPELQ	PCDHGB5	786	Q9Y5G0
EHLSCSSSPHLPFSE	MAP3K13	6	O43283
GEETETQTCPPHTEH	PRSS36	571	Q5K4E3
DTATLCESKFPSPHH	CEFIP	241	Q711Q0
VNSPHHSTQSDTCPL	KCNC1	476	P48547
LCVPDPIFNSEHHHS	C2CD3	1066	Q4AC94
PSHATHSLFTCPENE	BRCA2	2246	P51587
HEDPGQATLSTTHPE	CHD6	2316	Q8TD26
CSHQHLPQEQEPTSE	GAB4	181	Q2WGN9
HSLPCTPHTGAEDAE	CENPT	256	Q96BT3
PVFDITHQTPLCEEH	INO80D	496	Q53TQ3
HHSTPTISLSSCQPD	KIRREL3	646	Q8IZU9
PPQEEVLGNEHSHCT	CRYBG1	596	Q9Y4K1
DPAGHSQTTVPCVTH	DGLUCY	141	Q7Z3D6
PADEEVSHITSSACP	CACNA1H	2096	O95180
PITHPNDQEAHSSIC	DYNAP	46	Q8N1N2
ASGCHSHPEEQPTSI	MLPH	251	Q9BV36
SEQVSHHPPISACHA	OSBPL3	626	Q9H4L5
LHSEPRPNEHNCSAS	PKD1	2946	P98161
EVHCDSAAVSHEPTP	FAM114A1	31	Q8IWE2
ISEQVSHHPPISACH	OSBPL7	576	Q9BZF2
TESPHSSASPCQEHK	FOXA2	301	Q9Y261
DIPIDHPSCSKQHAV	SNIP1	291	Q8TAD8
NEHSAHCPHTPEFSV	RPAIN	181	Q86UA6
ENCCPINPTTEHSTH	TMEM131L	1546	A2VDJ0
SVQQDHLSRHPPETC	SPATA31A7	296	Q8IWB4
PVSPQHHELTSLFEC	SIAH2	66	O43255
PNSSHHLDAVPCSTT	SMARCB1	136	Q12824
TSDAEHQCQSPQHEP	TRIOBP	1091	Q9H2D6
DCSNNPISEHFHPTV	TENT5C	196	Q5VWP2
SVQQDHLSRHPPETC	SPATA31A3	296	Q5VYP0
HNASLHPTPEQCEAV	RNF213	4386	Q63HN8
TECQLTHSHPACPLE	ZSWIM9	116	Q86XI8
SDSDLSDHHEPICKP	SSH2	461	Q76I76
SVQQDHLSRHPPETC	SPATA31A5	296	Q5VU36
SPNFTPGEHCEEHVA	RMC1	626	Q96DM3
SEEPEDSVHRSPCHA	ZNF646	1486	O15015
EEEPVHLPCNHSTIS	TRAV26-2	31	A0A0B4J265
SSQEAADTPDTRHPC	YJU2B	366	P13994
PQTHETALHCAAASP	TNKS2	361	Q9H2K2
CRTQEHAHSENPSPT	YAE1	186	Q9NRH1
SNQNSCLPSHELTHP	ZNF233	351	A6NK53
HSECILESPEHLPSN	ZBTB49	261	Q6ZSB9
PHTHCPEVDSDTQPK	WNK1	1631	Q9H4A3
SPCQSPSHPEELHSS	PRR30	141	Q53SZ7
TSPSIDHDIAHIPAS	ARHGAP21	811	Q5T5U3
DEQTPLVNCHTPHSN	TULP3	66	O75386
TPSPQDHDTDLTCHV	SIGLEC11	216	Q96RL6
TFPHPHETTGDAQCS	ZBBX	341	A8MT70
HPVTCSHFTQDLHPE	ZNF722	86	A0A1W2PQL4
PCKSQDSDHPPSHDT	ZNF473	291	Q8WTR7
VVESPSHCVSADSPD	GARIN5B	311	Q8N5Q1