Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionflavin adenine dinucleotide binding

MAOA ACADVL AOX1 DLD MTO1 NOS2 CYB5R2

1.76e-0794877GO:0050660
GeneOntologyMolecularFunctionoxidoreductase activity

PCYOX1L HSD3B7 NOX1 MAOA ACADVL AOX1 DLD DECR2 CYP2S1 HADH IDH3G NOS2 CYB5R2

2.62e-057668713GO:0016491
GeneOntologyMolecularFunctionshort-chain fatty acid transmembrane transporter activity

SLC22A9 SLC22A10

1.86e-045872GO:0015636
GeneOntologyMolecularFunctionNAD binding

AOX1 DLD HADH IDH3G

2.91e-0473874GO:0051287
GeneOntologyMolecularFunctionglycerol channel activity

AQP7B AQP7

3.89e-047872GO:0015254
GeneOntologyMolecularFunctionurea transmembrane transporter activity

AQP7B AQP7

6.62e-049872GO:0015204
GeneOntologyMolecularFunctionglycerol transmembrane transporter activity

AQP7B AQP7

6.62e-049872GO:0015168
GeneOntologyCellularComponentapicolateral plasma membrane

MPDZ CLDN7 CLDN8

2.12e-0428873GO:0016327
GeneOntologyCellularComponentbasolateral plasma membrane

SLC22A9 SLC22A10 AQP7B CLDN7 AQP7 CLDN8 SLC4A1

3.78e-04320877GO:0016323
GeneOntologyCellularComponentaggresome

TRIM73 TRIM50 TRIM74

6.15e-0440873GO:0016235
GeneOntologyCellularComponentbasal plasma membrane

SLC22A9 SLC22A10 AQP7B CLDN7 AQP7 CLDN8 SLC4A1

6.89e-04354877GO:0009925
GeneOntologyCellularComponentanchoring junction

MPP3 PTPN6 FAT2 NOX1 CD9 PTPRK MPDZ CLDN7 AQP7 CLDN8 SLC4A1 EHD3

7.04e-049768712GO:0070161
GeneOntologyCellularComponentcell-cell junction

MPP3 PTPN6 FAT2 PTPRK MPDZ CLDN7 AQP7 CLDN8 SLC4A1

7.85e-04591879GO:0005911
GeneOntologyCellularComponentbasal part of cell

SLC22A9 SLC22A10 AQP7B CLDN7 AQP7 CLDN8 SLC4A1

1.01e-03378877GO:0045178
MousePhenohypochlorhydria

TRIM73 TRIM50 TRIM74

5.11e-067753MP:0008001
MousePhenoabnormal digestive secretion

TRIM73 TRIM50 NOS2 TRIM74

3.53e-0535754MP:0000501
DomainFd_Rdtase_FAD-bd

NOX1 NOS2 CYB5R2

8.66e-0519863IPR017927
DomainFAD_FR

NOX1 NOS2 CYB5R2

8.66e-0519863PS51384
DomainRiboflavin_synthase-like_b-brl

NOX1 NOS2 CYB5R2

8.66e-0519863IPR017938
Domain-

PCYOX1L MAOA DLD MTO1

1.28e-04568643.50.50.60
DomainFAD/NAD-binding_dom

PCYOX1L MAOA DLD MTO1

1.37e-0457864IPR023753
DomainPeptidase_M13

MMEL1 ECE2

4.34e-047862PF01431
DomainPeptidase_M13_C

MMEL1 ECE2

4.34e-047862IPR018497
DomainPeptidase_M13

MMEL1 ECE2

4.34e-047862IPR000718
DomainPeptidase_M13_N

MMEL1 ECE2

4.34e-047862PF05649
DomainPeptidase_M13_N

MMEL1 ECE2

4.34e-047862IPR008753
DomainZnf-RING_LisH

TRIM73 TRIM50 TRIM74

5.09e-0434863IPR027370
Domainzf-RING_UBOX

TRIM73 TRIM50 TRIM74

5.09e-0434863PF13445
DomainConA-like_dom

MEP1A FAT2 PTPRK TRIM50 ADGRV1 RYR2

5.23e-04219866IPR013320
DomainTYR_PHOSPHATASE_2

PTPN6 DUSP23 STYX PTPRK

6.97e-0487864PS50056
DomainTYR_PHOSPHATASE_dom

PTPN6 DUSP23 STYX PTPRK

6.97e-0487864IPR000387
Domain-

PTPN6 DUSP23 STYX PTPRK

8.60e-04928643.90.190.10
DomainFlavoprot_Pyr_Nucl_cyt_Rdtase

NOS2 CYB5R2

9.21e-0410862IPR001709
DomainProt-tyrosine_phosphatase-like

PTPN6 DUSP23 STYX PTPRK

1.13e-0399864IPR029021
DomainOxRdtase_FAD/NAD-bd

NOS2 CYB5R2

1.34e-0312862IPR001433
DomainDHS-like_NAD/FAD-binding_dom

DHPS HACL1

1.34e-0312862IPR029035
DomainNAD_binding_1

NOS2 CYB5R2

1.34e-0312862PF00175
DomainL27

MPP3 MPDZ

1.58e-0313862SM00569
DomainL27

MPP3 MPDZ

1.58e-0313862PS51022
DomainL27_dom

MPP3 MPDZ

1.58e-0313862IPR004172
DomainMAM_1

MEP1A PTPRK

2.41e-0316862PS00740
DomainPTPc_motif

PTPN6 DUSP23 PTPRK

2.54e-0359863SM00404
DomainTyr_Pase_cat

PTPN6 DUSP23 PTPRK

2.54e-0359863IPR003595
DomainMAM

MEP1A PTPRK

2.72e-0317862SM00137
DomainMAM

MEP1A PTPRK

3.06e-0318862PF00629
DomainMAM_dom

MEP1A PTPRK

3.06e-0318862IPR000998
DomainMAM_2

MEP1A PTPRK

3.06e-0318862PS50060
DomainBBOX

TRIM73 TRIM50 TRIM74

3.97e-0369863SM00336
Domain-

TRIM73 TRIM50 TRIM74

4.30e-03718634.10.45.10
Domainzf-B_box

TRIM73 TRIM50 TRIM74

4.47e-0372863PF00643
DomainClaudin_CS

CLDN7 CLDN8

4.56e-0322862IPR017974
DomainCLAUDIN

CLDN7 CLDN8

4.56e-0322862PS01346
DomainTyr_Pase_AS

PTPN6 DUSP23 PTPRK

4.65e-0373863IPR016130
DomainMFS_1

SLC22A9 SLC18A3 SLC22A10

5.39e-0377863PF07690
DomainMFS

SLC22A9 SLC18A3 SLC22A10

5.39e-0377863IPR011701
DomainZF_BBOX

TRIM73 TRIM50 TRIM74

6.00e-0380863PS50119
DomainZnf_B-box

TRIM73 TRIM50 TRIM74

6.21e-0381863IPR000315
DomainMetalloPept_cat_dom

MEP1A MMEL1 ECE2

6.21e-0381863IPR024079
Domain-

MEP1A MMEL1 ECE2

6.21e-03818633.40.390.10
DomainTYR_PHOSPHATASE_1

PTPN6 DUSP23 PTPRK

7.33e-0386863PS00383
DomainClaudin

CLDN7 CLDN8

7.33e-0328862IPR006187
PathwayKEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM

MAOA GAMT DLD ALAS2

1.50e-0531694M766
PathwayWP_TRYPTOPHAN_METABOLISM

MAOA AOX1 DLD HADH

1.93e-0533694M39500
PathwayKEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION

HIBCH AOX1 DLD HADH

6.16e-0544694M11835
Pubmed

Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.

TRIM73 TRIM50 TRIM74

1.51e-08387326196062
Pubmed

TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.

TRIM73 TRIM50 TRIM74

1.51e-08387322872646
Pubmed

Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.

TRIM73 TRIM50 TRIM74

1.51e-07587318398435
Pubmed

Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.

TRIM73 TRIM50 TRIM74

1.51e-07587320049703
Pubmed

TRIM50 regulates Beclin 1 proautophagic activity.

TRIM73 TRIM50 TRIM74

3.01e-07687329604308
Pubmed

TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.

TRIM73 TRIM50 TRIM74

3.01e-07687336178239
Pubmed

Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.

TRIM73 TRIM50 TRIM74

5.25e-07787326025256
Pubmed

Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.

CLDN7 CLDN8

6.19e-06287218799195
Pubmed

NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes.

NOX1 NOS2

6.19e-06287223801050
Pubmed

Two pools of IRE1α in cardiac and skeletal muscle cells.

ERN1 RYR2

6.19e-06287231051095
Pubmed

Hypoxia induces nitric oxide synthase in rheumatoid synoviocytes: consequences on NADPH oxidase regulation.

NOX1 NOS2

6.19e-06287222329647
Pubmed

Expression of claudin-7 and -8 along the mouse nephron.

CLDN7 CLDN8

6.19e-06287214722018
Pubmed

iNOS- and NOX1-dependent ROS production maintains bacterial homeostasis in the ileum of mice.

NOX1 NOS2

6.19e-06287229210363
Pubmed

Course of Brugia malayi infection in C57BL/6J NOS2 +/+ and -/- mice.

PRKDC NOS2

6.19e-06287211426950
Pubmed

Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guérin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity.

PRKDC NOS2

6.19e-06287217982083
Pubmed

PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease.

GAMT PFN2

6.19e-06287229449460
Pubmed

METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction.

ERN1 NOS2

6.19e-06287226228140
Pubmed

Mitochondrial diaphorases as NAD⁺ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.

DLD CYB5R2

6.19e-06287224391134
Pubmed

DNA-PKcs function regulated specifically by protein phosphatase 5.

PPP5C PRKDC

6.19e-06287214734805
Pubmed

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.

TRIM73 TRIM50 TRIM74

8.27e-061687322792322
Pubmed

Identification of a novel murine organic anion transporter like protein 1 (OATLP1) expressed in the kidney.

SLC22A9 SLC22A10

1.85e-05387217079864
Pubmed

Characterization of mouse organic anion transporter 5 as a renal steroid sulfate transporter.

SLC22A9 SLC22A10

1.85e-05387216150593
Pubmed

Differences in the expression profiles of claudin proteins in human gastric carcinoma compared with non‑neoplastic mucosa.

CLDN7 CLDN8

1.85e-05387229901188
Pubmed

Renal expression of organic anion transporter Oat5 in rats and mice exhibits the female-dominant sex differences.

SLC22A9 SLC22A10

1.85e-05387220865662
Pubmed

Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney.

SLC22A9 SLC22A10

1.85e-05387220332632
Pubmed

Interactions of the scid or beige mutations with the viable motheaten mutation.

PTPN6 PRKDC

1.85e-0538728781712
Pubmed

ATF4 and IRE1α inhibit DNA repair protein DNA-dependent protein kinase 1 induced by heat shock.

ERN1 PRKDC

1.85e-05387223001845
Pubmed

Molecular assembly of CD46 with CD9, alpha3-beta1 integrin and protein tyrosine phosphatase SHP-1 in human macrophages through differentiation by GM-CSF.

PTPN6 CD9

1.85e-05387211858824
Pubmed

Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target.

NOX1 NOS2

1.85e-05387225317947
Pubmed

Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host.

PRKDC NOS2

1.85e-05387221576322
Pubmed

Attenuated nephritis in inducible nitric oxide synthase knockout C57BL/6 mice and pulmonary hemorrhage in CB17 SCID and recombination activating gene 1 knockout C57BL/6 mice infected with Leptospira interrogans.

PRKDC NOS2

1.85e-05387221576342
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

MPP3 PTPN6 DUSP23 STYX PPP5C PTPRK DHPS MPDZ DLD PRKDC VBP1

3.16e-05974871128675297
Pubmed

Anticancer Mechanisms in Two Murine Bone Marrow-Derived Dendritic Cell Subsets Activated with TLR4 Agonists.

NOX1 NOS2

3.70e-05487229500244
Pubmed

Expression of claudin-5, -7, -8 and -9 in cervical carcinoma tissues and adjacent non-neoplastic tissues.

CLDN7 CLDN8

3.70e-05487226464708
Pubmed

A natural model of Leishmania major infection reveals a prolonged "silent" phase of parasite amplification in the skin before the onset of lesion formation and immunity.

PRKDC NOS2

3.70e-05487210878373
Pubmed

Neuronal nitric oxide synthase is necessary for elimination of Giardia lamblia infections in mice.

PRKDC NOS2

3.70e-05487216365445
Pubmed

Identification of claudin‑1, ‑3, ‑7 and ‑8 as prognostic markers in human laryngeal carcinoma.

CLDN7 CLDN8

3.70e-05487231115553
Pubmed

Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members.

SLC22A9 SLC22A10

3.70e-05487219417012
Pubmed

Isolation of a family of organic anion transporters from human liver and kidney.

SLC22A9 SLC22A10

3.70e-05487211327718
Pubmed

G-CSF mobilizes CD34+ regulatory monocytes that inhibit graft-versus-host disease.

PRKDC NOS2

3.70e-05487225834108
Pubmed

Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease.

PRKDC CLDN8

3.70e-05487234296202
Pubmed

Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney.

SLC22A9 SLC22A10

3.70e-05487215068970
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

CERK MAOA HIBCH ACADVL TCIRG1 DLD ALAS2 HADH MTO1 IDH3G CYB5R2

6.06e-051047871118614015
Pubmed

a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a.

TCIRG1 SLC4A1

6.16e-05587211498539
Pubmed

Both inducible nitric oxide synthase and NADPH oxidase contribute to the control of virulent phase I Coxiella burnetii infections.

NOX1 NOS2

6.16e-05587215501800
Pubmed

Defects in cell-mediated immunity affect chronic, but not innate, resistance of mice to Mycobacterium avium infection.

PRKDC NOS2

6.16e-0558729144497
Pubmed

Interferon-gamma is required for innate immunity to Cryptosporidium parvum in mice.

PRKDC NOS2

6.16e-05587210950807
Pubmed

Bone Morphogenic Protein 4 Mediates NOX1-Dependent eNOS Uncoupling, Endothelial Dysfunction, and COX2 Induction in Type 2 Diabetes Mellitus.

NOX1 NOS2

6.16e-05587226121233
Pubmed

T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells.

PRKDC NOS2

9.22e-05687227622331
Pubmed

Differential expression and subcellular localization of claudin-7, -8, -12, -13, and -15 along the mouse intestine.

CLDN7 CLDN8

9.22e-05687216651389
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

CERK KCNA4 SRGAP3 DYNC2I1 DECR2 ADGRV1 PFN2

1.05e-0443087732581705
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

FAU KCNA4 PPP5C ACADVL SRGAP3 DLD DARS1 ACTL6B IDH3G PFN2 RYR2

1.28e-041139871136417873
Pubmed

Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation.

EIF4A3 DARS1 IDH3G PFN2

1.29e-0410287431722399
Pubmed

Genetic polymorphisms associated with priapism in sickle cell disease.

NOS2 SLC4A1

1.72e-04887217408468
Pubmed

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.

CLDN7 CLDN8

1.72e-0488729892664
Pubmed

Claudins in human cancer: a review.

CLDN7 CLDN8

1.72e-04887219924644
Pubmed

A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities.

HACL1 DECR2 NOS2

1.86e-044487320178365
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

HIBCH ACADVL DLD HADH IDH3G RYR2

1.88e-0433187629199018
Pubmed

Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model.

PRKDC NOS2

2.20e-04987216239576
Pubmed

Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations.

ATG3 RYR2

2.20e-04987223829686
Pubmed

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry.

MAOA HIBCH ACADVL DLD HADH IDH3G

2.27e-0434387628130547
Pubmed

SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart.

ALAS2 RYR2

2.75e-041087219386262
Pubmed

Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening.

ERN1 PRKDC

2.75e-041087225495526
Pubmed

claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing.

CLDN7 CLDN8

2.75e-041087211585919
Pubmed

Permeability barrier dysfunction in transgenic mice overexpressing claudin 6.

CLDN7 CLDN8

2.75e-041087211923212
Pubmed

Expression of claudins in murine tooth development.

CLDN7 CLDN8

3.35e-041187217075866
Pubmed

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development.

ALAS2 SLC4A1

3.35e-041187218094026
Pubmed

Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.

PRKDC NOS2

3.35e-041187228973896
Pubmed

Erythropoietin contributes to implantation: ectopic hemoglobin synthesis in decidual cells of mice.

ALAS2 SLC4A1

3.35e-041187217300687
Pubmed

Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease.

MMEL1 ECE2

4.02e-041287222027013
Pubmed

Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins.

CLDN7 CLDN8

4.02e-041287210601346
Pubmed

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

HIBCH ACADVL DLD HADH MTO1 IDH3G

4.03e-0438287629222160
Pubmed

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.

PTPN6 PRKDC

4.74e-041387222724066
Pubmed

Molecular physiology of renal organic anion transporters.

SLC22A9 SLC22A10

4.74e-041387216403838
Pubmed

cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner.

ACADVL EIF4A3

4.74e-041387218337751
Pubmed

Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.

SLC22A9 SLC22A10

4.74e-041387215369770
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

MPP3 MPDZ DLD ADCY3 SLC4A1 EHD3

5.48e-0440587638187761
Pubmed

Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.

NOS2 NLRC3

5.52e-041487226320999
Pubmed

Genome-wide association study of alcohol dependence implicates a region on chromosome 11.

CARS1 ADCY3

5.52e-041487220201924
Pubmed

Mitochondrial FAD shortage in SLC25A32 deficiency affects folate-mediated one-carbon metabolism.

ACADVL DLD

5.52e-041487235727412
Pubmed

Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland.

CLDN7 CLDN8

5.52e-041487215366020
Pubmed

Loss of inherited genomic imprints in mice leads to severe disruption in placental lipid metabolism.

ACADVL HADH

6.36e-041587225662615
Pubmed

Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.

PTPN6 PTPRK

7.26e-04168728875997
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

ADGRV1 ADCY3

7.26e-041687217567809
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

SLC22A9 SLC22A10

7.26e-041687219679677
Pubmed

The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.

EIF4A3 DARS1 PRKDC

7.33e-047087330559450
Pubmed

Identification of a polymorphic, neuron-specific chromatin remodeling complex.

SRGAP3 ACTL6B

8.21e-041787212368262
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPN6 PTPRK

8.21e-041787219727691
Pubmed

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2.

CLDN7 CLDN8

8.21e-041787231171776
Pubmed

BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites.

EIF4A3 DARS1 PRKDC

8.29e-047387332347575
Pubmed

The Mediator complex protein Med31 is required for embryonic growth and cell proliferation during mammalian development.

ALAS2 SLC4A1

9.22e-041887220347762
Pubmed

Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.

MAOA SLC18A3 RYR2

9.68e-047787329445148
Pubmed

Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function.

CLDN7 CLDN8

1.03e-031987222155109
Pubmed

Biology of claudins.

CLDN7 CLDN8

1.03e-031987218480174
Pubmed

Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.

ECE2 RYR2

1.14e-032087219626040
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

FAU EIF4A3 DLD DARS1 PRKDC IDH3G PFN2 GPAT4 VBP1 LRRC41

1.18e-031257871037317656
Pubmed

An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.

MPP3 KCNA4 PFN2

1.24e-038487315123239
Pubmed

Multifunctional strands in tight junctions.

CLDN7 CLDN8

1.26e-032187211283726
Pubmed

Claudin-based barrier in simple and stratified cellular sheets.

CLDN7 CLDN8

1.26e-032187212231346
Pubmed

Tight junction proteins.

CLDN7 CLDN8

1.26e-032187212475568
Cytoband6q16.2

USP45 PRDM13

1.27e-0498726q16.2
GeneFamilyAtypical dual specificity phosphatases

DUSP23 STYX

1.40e-0318562896
GeneFamilyClaudins

CLDN7 CLDN8

2.29e-0323562488
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM73 TRIM50 TRIM74

3.18e-039556359
CoexpressionHALLMARK_FATTY_ACID_METABOLISM

MAOA HIBCH ACADVL DLD HADH IDH3G AQP7

9.12e-07158867M5935
CoexpressionFAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON

ERICH3 PTPRK ACADVL DYNC2I1 PTCHD4 RYR2

1.82e-05166866M39026
ToppCelldroplet-Liver-Npc-21m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1A GAMT ACADVL HACL1 DECR2 HADH

3.79e-071438760cd332c128710291a39957d3da22953352f5c382
ToppCelldroplet-Liver-Npc-21m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1A GAMT ACADVL HACL1 DECR2 HADH

4.28e-0714687624e63124116b9a6796ae0495fc69dc6b6af28c38
ToppCelldroplet-Liver-Npc-21m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1A GAMT ACADVL HACL1 DECR2 HADH

4.28e-07146876ae43d418492177546b7f85afffb4287d40815f88
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT2 CD9 SERPINB3 CYP2S1 NOS2 UNC5D

1.46e-06180876535a890bde0d978b461c2d4c571529b585c76b21
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOX1 CD9 TMPRSS13 HADH IDH3G CLDN8

1.99e-06190876a124e1c12af70161b9ead5d677afa660610444ee
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERICH3 TRIM73 SRGAP3 DYNC2I1 ADGRV1 DNAH7

2.18e-06193876ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOX1 MAOA CD9 CLDN7 HADH NOS2

2.46e-061978769ae6d987e65972e1fb21aa407788d5e3ff41ad64
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOX1 MAOA CD9 CLDN7 HADH NOS2

2.46e-06197876c0250509836f1be04f5e54386191d7bb1e1da652
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT2 CD9 PTPRK SRGAP3 CLDN7 CYP2S1

2.68e-06200876ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3|TCGA-Thryoid / Sample_Type by Project: Shred V9

AOX1 ADGRV1 KLHL33 DNAH7 RYR2

1.30e-051548754e9203c220a44c70cd7979796a0b461991422257
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SMIM10 AOX1 ALAS2 CYB5R2 SLC4A1

1.61e-051618758ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAMT ACADVL HACL1 ALAS2 CLDN8

1.81e-05165875dba630e205eb3725195f8861e4af5b745ccfdc74
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAMT ACADVL HACL1 ALAS2 CLDN8

1.81e-05165875a508d66031c1a46b062afbee3cde1cbd0c163a03
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAMT ACADVL HACL1 ALAS2 CLDN8

1.81e-05165875b03c8c3110f32257e78838885b313a922af73c98
ToppCell368C-Lymphocytic-NK_cells-NK_cell_C|368C / Donor, Lineage, Cell class and subclass (all cells)

ERN1 SRGAP3 ALAS2 KLHL20 SLC4A1

1.97e-051688750372c06b70f0ba95bf8cd1363ca7c5f31207f094
ToppCellFrontal_cortex-Macroglia|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABHD4 CD9 GAMT ATG3 CYB5R2

2.27e-05173875ac70145e093ef0df43811e7c67a865ccdd45a5e3
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 PTPRK SLC22A10 PTCHD4 UNC5D

2.60e-051788755522b179c2e7dd707de01e2df10556349d0382a6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 PTPRK SLC22A10 PTCHD4 UNC5D

2.60e-05178875731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOX1 CD9 TRIM50 NOS2 TRIM74

2.67e-051798756405010e8136a4d9bab356f628e36e3194911112
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMEL1 CD9 SERPINB3 CDC20B CLDN7

3.05e-05184875c2ca984551baf4becbefbe58bd1889828542b045
ToppCellHippocampus-Macroglia|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABHD4 CD9 EIF4A3 HACL1 HADH

3.05e-05184875a1d039ddf1e2a87b870f3ce6d139be56090349df
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT2 TMPRSS13 CLDN7 CYP2S1 CLDN8

3.21e-0518687537b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERICH3 SLC18A3 ACTL6B ECE2 RYR2

3.21e-0518687515f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCellfacs-MAT-Fat-3m-Epithelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP3 ALAS2 ADGRV1 SLC4A1

3.34e-0593874dbfaa7f23d25f5c286ab7ca3ca795b734cb95153
ToppCellfacs-MAT-Fat-3m-Epithelial-epithelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP3 ALAS2 ADGRV1 SLC4A1

3.34e-05938740d6d1d8dd9c91ba31eb35a4b5979d087890936c1
ToppCellfacs-MAT-Fat-3m-Epithelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP3 ALAS2 ADGRV1 SLC4A1

3.34e-0593874abffb1fd5a919b7c08e62e1c3c08a8dd8783a4ca
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT2 TMPRSS13 CLDN7 CYP2S1 CLDN8

3.56e-0519087547e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FAT2 TMPRSS13 CLDN7 CYP2S1 CLDN8

3.56e-05190875261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEP1A MAOA CD9 SLC39A2 CLDN7

3.74e-051928759f7e0d610741288d0779bd7c02852c791431e4ea
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD9 CLDN7 PFN2 CLDN8 SLC4A1

3.74e-051928754842a55650fc4687c9184d498a8c05c259d15186
ToppCellfacs-Lung-EPCAM-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT2 TMPRSS13 CLDN7 CYP2S1 CLDN8

3.74e-0519287512096302a3a4d26e21ca04357aa557143f482155
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT2 CD9 SERPINB3 CYP2S1 UNC5D

3.83e-051938757c34abdcb8839b9fb25457a79af6c5e7b9714b21
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD9 CLDN7 PFN2 CLDN8 SLC4A1

3.93e-0519487533e63160fc3308d9b95d657b0d20fa3d9960ece6
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEP1A MAOA AQP7B DECR2 CLDN7

3.93e-05194875fcbf9c4f3801ab1a34fcd62c752fabc97fc7bde1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD9 CLDN7 PFN2 CLDN8 SLC4A1

4.02e-051958750ac7762197cdd8d643f87148573a8df6e936c1b0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD9 CLDN7 PFN2 CLDN8 SLC4A1

4.12e-05196875cd8c22c6f52f068a33525723108d6b5b23fe822d
ToppCellcellseq-Epithelial-Epithelial_Airway|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT2 SERPINB3 SRGAP3 CYP2S1 PFN2

4.12e-05196875faa39c567f24403e511b240c1d1a654ffadd8473
ToppCell3'-Broncho-tracheal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT2 CD9 SERPINB3 SRGAP3 CYP2S1

4.22e-051978755d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCell3'-Adult|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOX1 MAOA CD9 CLDN7 CLDN8

4.33e-05198875302adb42089ff22fffc4f01af572ca2e151f7ce7
ToppCell3'-Broncho-tracheal-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT2 CD9 SERPINB3 SRGAP3 CYP2S1

4.33e-05198875aa6e7218ee6230902854e66c444b544218b30c0e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT2 DUSP23 CD9 SERPINB3 CYP2S1

4.33e-0519887522935a8afac54021f68b5f7a5accf51523e2f336
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT2 CD9 SERPINB3 CYP2S1 NOS2

4.33e-051988755374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellcellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT2 CD9 SERPINB3 SRGAP3 CYP2S1

4.43e-05199875974f71b56f66243c78f2f297a1540e0e186df530
ToppCellsuprabasal_cell|World / shred by cell class for turbinate

FAT2 CD9 SERPINB3 CLDN7 NOS2

4.43e-05199875bfab5380ef074d14f0b5ed10851ad5c898eb9a58
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT2 CD9 SERPINB3 SRGAP3 CYP2S1

4.43e-051998754099df3c052a9536d72ba01492317be7d83a79ad
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FAT2 CD9 SRGAP3 CLDN7 CYP2S1

4.54e-0520087597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellBronchus_Control_(B.)-Epithelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ERICH3 CD9 SERPINB3 CLDN7 DNAH7

4.54e-05200875f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCelldroplet-Heart-nan-3m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP210L ALAS2 CYP2S1 SLC4A1

1.64e-04140874ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MEP1A NOS2 CLDN8

1.70e-0455873c4889dc9658c215f370bbe0b668ba66bd99eb749
ToppCellcritical-Lymphoid-NKT|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ERICH3 SERPINB3 CLDN7 DNAH7

1.77e-04143874dca035bfbfd1665c04076c43da8bc18a1502b9de
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell|E18.5-samps / Age Group, Lineage, Cell class and subclass

TMPRSS13 CYP2S1 CLDN8 SLC4A1

2.08e-0414987482edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar|E18.5-samps / Age Group, Lineage, Cell class and subclass

TMPRSS13 CYP2S1 CLDN8 SLC4A1

2.08e-0414987414a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FAT2 PRDM13 CLDN8

2.21e-046087348adafeec1810bce5f118fa63d4a8ee7ab9ca0f7
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

FAT2 PRDM13 CLDN8

2.21e-0460873a83afb89dbfc2e1cdfce57320d89c980bd8fb820
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SRGAP3 SMIM10 TMEM218 HADH

2.30e-0415387491e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SRGAP3 SMIM10 TMEM218 HADH

2.30e-04153874f17f62646633cf95c810dcd5328978058741b276
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAMT HACL1 DECR2 ALAS2

2.30e-04153874d9e2c386875bc15e1e6e75dc7acf05c0dc8c306b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NOX1 ALAS2 SLC4A1 EHD3

2.41e-04155874a16e3a72badafa78a3efc4f4ab62396f0ce99d1e
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FAT2 SLC18A3 CLDN7

2.43e-04628733eec7f31de7cc24762c5b180475650676437dc76
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FAT2 SLC18A3 CLDN7

2.43e-0462873f5f5441f5be00ab80a7827c4af1afbe45c552c2e
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FAT2 SLC18A3 CLDN7

2.43e-04628736e81a37b9defa96528654bee1b23152108d9c0b7
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAMT HACL1 DECR2 HADH

2.54e-041578745af1b77dd08cf7f3b629e0f59defdf1ebee5cc3e
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINB3 CDC20B CLDN7 AQP7

2.54e-04157874c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

AOX1 ADGRV1 DNAH7 RYR2

2.60e-041588748e48952af0831a1fc71ad422e8216b5a92a75991
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

AOX1 ADGRV1 DNAH7 RYR2

2.60e-04158874e5b55c15a8c99c8d7fc94949f0d3c22e0c3fee7b
ToppCellTCGA-Thryoid-Solid_Tissue_Normal|TCGA-Thryoid / Sample_Type by Project: Shred V9

AOX1 ADGRV1 DNAH7 RYR2

2.60e-0415887455214d674808584e4d48f8c5e3b8c0e206cb9bb8
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1A ALAS2 HADH SLC4A1

2.66e-04159874c34a7d227dbda2d7c76f937e1a58552b14bd40b5
ToppCellBL-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NOX1 SLC22A10 CDC20B NOS2

2.73e-041608743f737451d5713deed20061aa72a9ef77a9a2bc06
ToppCellHealthy/Control-RBC|World / Disease group and Cell class

PTPRK SRGAP3 ALAS2 SLC4A1

2.73e-04160874f10871238e7bdf3e1f65a17070000477196e50fe
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MMEL1 SRGAP3 CLDN8 SLC4A1

2.79e-04161874176a4a72bb4892932da3c834d1fea5e211847f92
ToppCellfacs-SCAT-Fat-18m-Epithelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1A ALAS2 CLDN7 SLC4A1

2.86e-04162874341fa357ad7bdbef30864e8062f161e60185ffc9
ToppCellfacs-SCAT-Fat-18m-Epithelial-epithelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1A ALAS2 CLDN7 SLC4A1

2.86e-041628747215f6eb2b65dea455e2eec722a9c38e6958b120
ToppCellfacs-SCAT-Fat-18m-Epithelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEP1A ALAS2 CLDN7 SLC4A1

2.86e-041628747fa93efa2039d68a4e8214fa143bcd3368349a2d
ToppCell11.5-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

TMPRSS13 DECR2 ALAS2 SLC4A1

2.92e-04163874e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-4|TCGA-Stomach / Sample_Type by Project: Shred V9

FAT2 SLC39A2 SERPINB3 CLDN8

2.92e-041638746a12b802cb181f979ebc72674f3626fb855024e3
ToppCell11.5-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

TMPRSS13 DECR2 ALAS2 SLC4A1

2.92e-0416387431b60e065bac4ad380247964e7574f210106ebae
ToppCellCOVID-mono3|COVID / Condition, Cell_class and T cell subcluster

HSD3B7 MAOA CD9 PTCHD4

2.92e-041638746ab4cbcd411b40920b81162c0f4b03ea67408f52
ToppCellCOVID-mono3-|COVID / Condition, Cell_class and T cell subcluster

HSD3B7 MAOA CD9 PTCHD4

2.92e-0416387426661c7a3a0a449ed32d4b3b28fc2fc0b237025d
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAMT SERPINB3 SRGAP3 PTCHD4

2.99e-041648748d1d0424943d3e98c8b6399dbf702e0035d0db7b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD9 PFN2 CLDN8 SLC4A1

2.99e-0416487483141be8dfed85511ea6afda7c76ff4b6b5ef021
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 CDC20B CLDN7 CLDN8

2.99e-041648746ea188e17895961cd112152fb111d08641cc5e45
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERICH3 AOX1 ACTL6B ADGRV1

3.06e-041658744b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CERK ERN1 PRDM13 NLRC3

3.13e-04166874bb93db4613c067c56614ab1ca39e73ee46484387
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CERK ERN1 PRDM13 NLRC3

3.13e-04166874c1f17a028bb27b8f202bcfffa7de7373b1cdd990
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD9 PFN2 CLDN8 SLC4A1

3.21e-04167874166b7b4ca0663cde6d88219ee0bcc1988d03dab8
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP210L ALAS2 NOS2 SLC4A1

3.21e-04167874bad33497ceeab968a7eb8a48b921c6f936390743
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 CLDN7 CYP2S1 CLDN8

3.35e-0416987408ac28c5ad8f5c5f9f54af341bf39e8f9417636e
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 CLDN7 CYP2S1 CLDN8

3.35e-04169874e5abd41db1e6724ad900e37658fa063b8e522908
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-hematopoietic_progenitor-erythroid_progenitor_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNA4 SLC39A2 ALAS2 SLC4A1

3.43e-0417087474bb46826141bd1e80b4ce16e6bbfc770bd427d3
ToppCellCiliated_cells-A-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ERICH3 NOX1 SERPINB3 CLDN8

3.43e-041708743d3a03979014df3a05c49be18010c6b94d786707
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-hematopoietic_progenitor|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNA4 SLC39A2 ALAS2 SLC4A1

3.43e-041708746592ebe204b43b81c6b6da99e05da72c0983b3fa
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOX1 SLC39A2 CLDN7 KLHL33

3.51e-04171874f2b31c97bbcc5164fc279ed0362007878887ad5e
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMPRSS13 CDC20B CYP2S1 CLDN8

3.51e-041718744f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCellBAL-Mild-Myeloid-MoAM-MoAM4-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HSD3B7 CDC42EP2 ALAS2 SLC4A1

3.75e-04174874fe105550a43b935affc73e32796115d20328a2f8
ToppCellBAL-Mild-Myeloid-MoAM-MoAM4|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

HSD3B7 CDC42EP2 ALAS2 SLC4A1

3.75e-041748749191f6abb37ca65da5105f91e21689d11ec1059b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 SLC22A10 PTCHD4 UNC5D

3.83e-04175874030f93af5a96848b9118e2a8116e19ddae438d92
ToppCellBAL-Mild-Myeloid-MoAM-MoAM4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HSD3B7 CDC42EP2 ALAS2 SLC4A1

3.83e-04175874b2099b4ab1bf74497f454a99fffe5f5561b1f968
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD9 CLDN7 CYP2S1 CLDN8

3.83e-0417587438dec78efc99fe23479cba68cfa441e62bd6a08b
ToppCellBAL-Mild-Myeloid-MoAM-MoAM4-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HSD3B7 CDC42EP2 ALAS2 SLC4A1

3.83e-041758746e54b74c735f249c7bfab7087c1638065ec1dd2e
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOX1 CD9 NOS2 TRIM74

3.83e-041758740431897d7fcc9cefb516cd36987cf18b7f19a26a
Drugreduced diphosphopyridine nucleotide

HSD3B7 NOX1 MAOA HIBCH AOX1 DHPS TCIRG1 DLD HADH IDH3G NOS2

5.93e-083428511CID000000928
Drugcoenzyme 1

HSD3B7 NOX1 MAOA HIBCH AOX1 DHPS DLD DECR2 HADH IDH3G NOS2 ADCY3 RYR2

3.13e-075968513CID000000925
Drughydroxyl radicals

PCYOX1L HSD3B7 PTPN6 MMEL1 NOX1 MAOA PPP5C GAMT HIBCH PTPRK ACADVL AOX1 TCIRG1 DLD CYP2S1 HADH IDH3G NOS2

1.80e-0613418518CID000000961
Drughydride

HSD3B7 NOX1 MAOA HIBCH SLC18A3 DHPS TCIRG1 DLD DECR2 CYP2S1 HADH IDH3G NOS2 SLC4A1

2.42e-068358514CID000000783
Drugoxygen

PCYOX1L HSD3B7 NOX1 MAOA AOX1 DHPS TCIRG1 CYP2S1 ADGRV1 PFN2 NOS2

2.48e-064998511CID000000977
DrugNADP(H

HSD3B7 KCNA4 NOX1 AOX1 DLD DECR2 CYP2S1 HADH IDH3G NOS2 SLC4A1

4.19e-065278511CID000000930
DrugCoA group

HIBCH ACADVL SLC18A3 DLD HACL1 ACTL6B ALAS2 HADH IDH3G GPAT4

4.89e-064338510CID000000317
DrugAC1Q68Z5

HSD3B7 ACADVL SLC18A3 DLD HACL1 ALAS2 HADH IDH3G PFN2

1.39e-05386859CID000000181
DrugC015407

DLD IDH3G NOS2

1.40e-0513853CID003014226
Drugmeprobamate

MEP1A MMEL1 PTPRK ALAS2 CLDN8

1.98e-0588855CID000004064
DrugAC1N3SS3

ACADVL CARS1 DLD HADH

2.40e-0545854CID000000592
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

PPP5C ERN1 PTPRK DLD NOS2 ADCY3

2.14e-04295856EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Diseaserenal tubular acidosis (implicated_via_orthology)

TCIRG1 SLC4A1

2.27e-048852DOID:14219 (implicated_via_orthology)
Diseaseestrogen measurement

SLC22A9 SLC22A10

3.64e-0410852EFO_0011007
DiseaseSeizures

GAMT DHPS MPDZ ACTL6B NOS2

4.27e-04218855C0036572
DiseaseCognitive impairment

RYR2 DMXL1

4.44e-0411852HP_0100543
DiseaseHepatic Encephalopathy

MAOA PRKDC

6.27e-0413852C0019151
DiseaseHepatic Coma

MAOA PRKDC

6.27e-0413852C0019147
DiseaseFulminant Hepatic Failure with Cerebral Edema

MAOA PRKDC

6.27e-0413852C0751197
DiseaseHepatic Stupor

MAOA PRKDC

6.27e-0413852C0751198
Disease–

NOS2 SLC4A1

9.59e-0416852611162
DiseaseMalaria, susceptibility to

NOS2 SLC4A1

9.59e-0416852cv:C1970028
DiseaseMalaria

NOS2 SLC4A1

1.51e-0320852C0024530
Diseasepulmonary hypertension (biomarker_via_orthology)

NOX1 NOS2 RYR2

1.62e-0380853DOID:6432 (biomarker_via_orthology)
DiseaseHodgkins lymphoma

PTPRK SLC18A3 DECR2

1.73e-0382853EFO_0000183

Protein segments in the cluster

PeptideGeneStartEntry
GMGGGRVVAVEVLHG

ERICH3

1331

Q5RHP9
GFHLDLLLVVGMGGV

SLC4A1

701

P02730
VKGLSGNTMLGVGHV

ACTL6B

311

O94805
GGCGFLGEHVVRMLL

HSD3B7

16

Q9H2F3
IVGGIFSTTGMLHGI

ERGIC2

321

Q96RQ1
GIFMFHVTRGAGEVI

ADGRV1

3911

Q8WXG9
NDRTPLVMVHGFGGG

ABHD4

66

Q8TB40
LVMVHGFGGGVGLWI

ABHD4

71

Q8TB40
GSHGGGLASVRMELI

DMXL1

2141

Q9Y485
TVAEGGGELGVHMYL

ATG3

276

Q9NT62
VMCHVRRVGGAFGGK

AOX1

796

Q06278
GSVLVTHGGIEMGQG

AOX1

1036

Q06278
LADHLGMIAGGTGIT

CYB5R2

146

Q6BCY4
HRLDAGTFGTMGVGL

HACL1

416

Q9UJ83
VALIHGITMGGGVGL

HIBCH

136

Q6NVY1
GHMFDVVVIGGGISG

MAOA

11

P21397
QHKGVRGGRMTLVFG

NOS2

1001

P35228
HGIGGIVRGQTEESM

NOX1

221

Q9Y5S8
HVMAALGGRLYVAGG

KLHL33

411

A6NCF5
HGGRKMVGTLGRLAF

NLRC3

391

Q7RTR2
FGGIGKGHLMREVDA

MTO1

81

Q9Y2Z2
IVKHVTVIGGGLMGA

HADH

26

Q16836
GVTMGVHVAGRISGA

AQP7B

81

A0A075B734
GQHVVAGTPGRVFDM

EIF4A3

156

P38919
FIIGTDMGLISHGTR

DYNC2I1

876

Q8WVS4
RGTVAMLEGTFDGHG

CYP2S1

101

Q96SQ9
ALNFGGIGVVMGHEL

ECE2

636

P0DPD6
GEMATGNGRRLHLGI

VBP1

11

P61758
VVGRSAIFGGEHFML

PCYOX1L

106

Q8NBM8
HMVGVISVEGRPGLF

FAT2

1366

Q9NYQ8
GGSGIGFRIAEIFMR

DECR2

36

Q9NUI1
FGVTMGVHVAGRISG

AQP7

76

O14520
KLQGIEVGHFMGGDV

PRSS37

201

A4D1T9
ALNFGGIGMVIGHEI

MMEL1

601

Q495T6
GSRGAGIGERDGIMH

ALAS2

366

P22557
AGRVLVFVMGKEGVH

PFN2

106

P35080
IGAVGIGIAVVMIFG

CD9

196

P21926
FFVVMGVIGGLLGAT

CLCN6

336

P51797
YGGRHTVTMIPGDGI

IDH3G

51

P51553
RLGGGVGVIKMTHCE

KLHL20

591

Q9Y2M5
IHIGSGGGSDMFGDI

CDC42EP2

41

O14613
VGQVHGGLMGVIQRA

GPAT4

266

Q86UL3
VLGHGAEGTIVYRGM

ERN1

576

O75460
GDGMFSEVLHGLIGR

CERK

196

Q8TCT0
TGMIILGGGVVKHHI

DHPS

276

P49366
VRHGFMIVGEPFGGK

DNAH7

1601

Q8WXX0
MRVGVHTGTVLGGVL

ADCY3

411

O60266
AVEFLGHVGGVGIDM

DLD

241

P09622
VLAIGGGMKDGRLHI

CDC20B

416

Q86Y33
GGRVLEVGFGMAIAA

GAMT

61

Q14353
MGAGVGVAGCTRGHR

FIMP

1

Q96LL3
MSGAARGQGHFLGIV

PRDM13

261

Q9H4Q3
HMYVGVRAGGGIGDE

RYR2

4816

Q92736
GVGVARSPGTAMIFH

NUP210L

1526

Q5VU65
RTIIHCLNGGGRSGM

PTPRK

1371

Q15262
MRGGAADRSGLVHVG

MPP3

166

Q13368
IVPDYIAHMRGGGEG

SLC18A3

56

Q16572
LGASMDIHGGGFDLR

CARS1

356

P49589
GRAVSAHMGVLESGV

LRRC41

51

Q15345
MMVGGILGGHLSDRF

SLC22A9

156

Q8IVM8
MLVGGIIGGHVSDRF

SLC22A10

156

Q63ZE4
GKVLIMHGGLFSEDG

PPP5C

346

P53041
AMGHGTKGVFELLSG

PTCHD4

301

Q6ZW05
AVQVHGSVLGMVIGG

MEP1A

711

Q16819
LRSVVGIGVSGQMHG

SHPK

81

Q9UHJ6
HAGGGIGLERVTMLF

DARS1

466

P14868
IDGSLQMGGKVLVHG

STYX

106

Q8WUJ0
GMTGSRGLVLSGVLH

SERPINB3

316

P29508
IQMVKGGAFEGTLHG

EHD3

406

Q9NZN3
VVFGVGMRLVHLGTS

SLC39A2

206

Q9NP94
IVGMHDLGVGITLGA

ACADVL

166

P49748
ARIAMGGGIIFIVAG

CLDN7

116

O95471
LFLGGVGMVGTVAVT

CLDN8

11

P56748
GIGGHTRGLVASLDM

TRIM74

196

Q86UV6
HCGLRAMTGRIVGGA

TMPRSS13

316

Q9BYE2
GLYGIVEHSGSMREG

USP45

731

Q70EL2
KDGLGMIVRSIIHGG

MPDZ

1026

O75970
HISDYGFGGVMGRVR

SRGAP3

841

O43295
GVFGHLGGRLVMPNT

UNC5D

546

Q6UXZ4
MEALGSGHYVGGSIR

SMIM10

1

Q96HG1
AMETGGVIGIDFGHA

PRKDC

3931

P78527
HIKVMCEGGRYTVGG

PTPN6

166

P29350
GIGGHTRGLVASLDM

TRIM73

196

Q86UV7
MAGTVLGVGAGVFIL

TMEM218

1

A2RU14
EVAGRMLGGKVHGSL

FAU

66

P62861
GIGGHTRGLVASLDM

TRIM50

196

Q86XT4
LGVVHMAFGVVLGVF

TCIRG1

541

Q13488
VGVHCALGFGRTGTM

DUSP23

91

Q9BVJ7
RDLVMALSAGGHGGL

KCNA4

336

P22459
HSQILGGTMILVIGG

LRFN2

526

Q9ULH4