Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	sarcolemma	PSEN1 RYR1 CLTC SGCE FER1L5 ALOX12 ALOX5	7.44e-05	190	112	7	GO:0042383
GeneOntologyCellularComponent	intraciliary transport particle B	IFT57 RABL2B RABL2A	1.86e-04	21	112	3	GO:0030992
Domain	Clathrin_H-chain_propeller_rpt	CLTCL1 CLTC	3.44e-05	2	110	2	IPR022365
Domain	Clathrin-link	CLTCL1 CLTC	3.44e-05	2	110	2	PF09268
Domain	-	CLTCL1 CLTC	3.44e-05	2	110	2	2.130.10.110
Domain	Clathrin_heavy_chain	CLTCL1 CLTC	3.44e-05	2	110	2	IPR016341
Domain	Clathrin_H-chain_propeller_N	CLTCL1 CLTC	3.44e-05	2	110	2	IPR001473
Domain	Clathrin_H-chain_link/propller	CLTCL1 CLTC	3.44e-05	2	110	2	IPR016025
Domain	Clathrin_propel	CLTCL1 CLTC	3.44e-05	2	110	2	PF01394
Domain	Clathrin_H-chain_linker_core	CLTCL1 CLTC	3.44e-05	2	110	2	IPR015348
Domain	Clathrin_H-chain_linker	CLTCL1 CLTC	1.03e-04	3	110	2	IPR012331
Domain	DUF3446	EGR1 EGR3	1.03e-04	3	110	2	PF11928
Domain	DUF3446	EGR1 EGR3	1.03e-04	3	110	2	IPR021849
Domain	CLH	CLTCL1 CLTC	1.03e-04	3	110	2	SM00299
Domain	LipOase_mml	ALOX12 ALOX5	5.08e-04	6	110	2	IPR001885
Domain	LIPOXYGENASE_1	ALOX12 ALOX5	5.08e-04	6	110	2	PS00711
Domain	LipOase_C	ALOX12 ALOX5	5.08e-04	6	110	2	IPR013819
Domain	LIPOXYGENASE_2	ALOX12 ALOX5	5.08e-04	6	110	2	PS00081
Domain	LipOase_Fe_BS	ALOX12 ALOX5	5.08e-04	6	110	2	IPR020833
Domain	LipOase_CS	ALOX12 ALOX5	5.08e-04	6	110	2	IPR020834
Domain	Lipoxygenase	ALOX12 ALOX5	5.08e-04	6	110	2	PF00305
Domain	LIPOXYGENASE_3	ALOX12 ALOX5	5.08e-04	6	110	2	PS51393
Domain	LipOase	ALOX12 ALOX5	5.08e-04	6	110	2	IPR000907
Domain	UBA-like	USP24 USP25 TNRC6C TAB3	5.51e-04	64	110	4	IPR009060
Domain	Clathrin	CLTCL1 CLTC	7.08e-04	7	110	2	PF00637
Domain	CHCR	CLTCL1 CLTC	7.08e-04	7	110	2	PS50236
Domain	Clathrin_H-chain/VPS_repeat	CLTCL1 CLTC	9.40e-04	8	110	2	IPR000547
Domain	Glyco_hydro_47	USF3 EDEM1	9.40e-04	8	110	2	IPR001382
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DAB2IP ATG13 IST1 TNRC6C TENM2 STRIP1 RSBN1 CLTC KATNIP UBE3C	8.45e-07	407	112	10	12693553
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP CLTCL1 ACACA PIEZO1 DUSP5 TNRC6C RYR1 NCOR2 CELSR1 DIP2C UBE3C ALOX5 RAI1 HTT MVB12B	2.73e-06	1105	112	15	35748872
Pubmed	The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.	IFT57 RABL2B RABL2A	7.00e-06	12	112	3	28625565
Pubmed	The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma.	ALOX12 ALOX5	1.03e-05	2	112	2	30941737
Pubmed	RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.	RABL2B RABL2A	1.03e-05	2	112	2	27732084
Pubmed	Upregulation of NF-κB by USP24 aggravates ferroptosis in diabetic cardiomyopathy.	USP24 NFKB1	1.03e-05	2	112	2	38056575
Pubmed	Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin toxicity.	DGKE HTT	1.03e-05	2	112	2	22511757
Pubmed	Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing.	RABL2B RABL2A	1.03e-05	2	112	2	20138207
Pubmed	Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival.	EGR1 EGR3	1.03e-05	2	112	2	17513727
Pubmed	Common polymorphisms in 5-lipoxygenase and 12-lipoxygenase genes and the risk of incident, sporadic colorectal adenoma.	ALOX12 ALOX5	1.03e-05	2	112	2	17236225
Pubmed	The T cell receptor from an influenza-A specific murine CTL clone.	TRBV12-4 TRBV12-3	1.03e-05	2	112	2	2784852
Pubmed	Expression of lipoxygenase in human prostate cancer and growth reduction by its inhibitors.	ALOX12 ALOX5	1.03e-05	2	112	2	15010818
Pubmed	Inhibition of Early Growth Response 1 in the Hippocampus Alleviates Neuropathology and Improves Cognition in an Alzheimer Model with Plaques and Tangles.	PSEN1 EGR1	1.03e-05	2	112	2	28641077
Pubmed	Effect of nerve growth factor on AP-1, NF-kappa B, and Oct DNA binding activity in apoptotic PC12 cells: extrinsic and intrinsic elements.	PON1 NFKB1	1.03e-05	2	112	2	8811508
Pubmed	A dual role for EDEM1 in the processing of rod opsin.	RHO EDEM1	1.03e-05	2	112	2	19934218
Pubmed	Interaction between superantigen and T-cell receptor Vbeta element determines levels of superantigen-dependent cell-mediated cytotoxicity of CD8(+) T cells in induction and effector phases.	TRBV12-4 TRBV12-3	1.03e-05	2	112	2	19659929
Pubmed	Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.	CLTCL1 CLTC	1.03e-05	2	112	2	8733129
Pubmed	Consequences for enamel development and mineralization resulting from loss of function of ameloblastin or enamelin.	AMBN ENAM	1.03e-05	2	112	2	19758243
Pubmed	Relationship between lipoxygenase and human testicular cancer.	ALOX12 ALOX5	1.03e-05	2	112	2	14767568
Pubmed	Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies.	ALOX12 ALOX5	1.03e-05	2	112	2	20724598
Pubmed	A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease.	NFKB1 HTT	1.03e-05	2	112	2	25938884
Pubmed	Risk of non-medullary thyroid cancer influenced by polymorphic variation in the thyroglobulin gene.	TSHR TG	1.03e-05	2	112	2	14633662
Pubmed	CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.	CLTCL1 CLTC	1.03e-05	2	112	2	29097553
Pubmed	Upregulating DAB2IP expression via EGR-1 inhibition, a new approach for overcoming fractionated-irradiation-induced cross-tolerance to ionizing radiation and mitomycin C in tumor cells.	DAB2IP EGR1	1.03e-05	2	112	2	27834104
Pubmed	Human fibrocytes coexpress thyroglobulin and thyrotropin receptor.	TSHR TG	1.03e-05	2	112	2	22517745
Pubmed	Innate immune responses in NF-kappaB-repressing factor-deficient mice.	NKRF NFKB1	1.03e-05	2	112	2	16354699
Pubmed	Expression and prognostic value of the transcription factors EGR1 and EGR3 in gliomas.	EGR1 EGR3	1.03e-05	2	112	2	32518380
Pubmed	The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.	CLTCL1 CLTC	1.03e-05	2	112	2	20065094
Pubmed	Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.	RABL2B RABL2A	1.03e-05	2	112	2	10444334
Pubmed	A conserved sequence in the T-cell receptor beta-chain promoter region.	TRBV12-4 TRBV12-3	1.03e-05	2	112	2	3259318
Pubmed	Variants in RABL2A causing male infertility and ciliopathy.	RABL2B RABL2A	1.03e-05	2	112	2	33075816
Pubmed	Expression of lipoxygenase in human bladder carcinoma and growth inhibition by its inhibitors.	ALOX12 ALOX5	1.03e-05	2	112	2	14532840
Pubmed	A mutation in the enamelin gene in a mouse model.	AMBN ENAM	1.03e-05	2	112	2	17652207
Pubmed	Knockout of 5-lipoxygenase prevents dexamethasone-induced tau pathology in 3xTg mice.	PSEN1 ALOX5	1.03e-05	2	112	2	23634895
Pubmed	Immunoinhibitory effects of hypoxia-driven reprogramming of EGR1hi and EGR3 positive B cells in the nasopharyngeal carcinoma microenvironment.	EGR1 EGR3	1.03e-05	2	112	2	39197193
Pubmed	Modulation of lipopolysaccharide-induced memory insult, γ-secretase, and neuroinflammation in triple transgenic mice by 5-lipoxygenase.	PSEN1 ALOX5	1.03e-05	2	112	2	24332986
Pubmed	Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer's phenotype.	PSEN1 ALOX5	1.03e-05	2	112	2	28383037
Pubmed	RABL2 positively controls localization of GPCRs in mammalian primary cilia.	RABL2B RABL2A	1.03e-05	2	112	2	30578315
Pubmed	Nuclear factor kappa B-dependent Zif268 expression in hippocampus is required for recognition memory in mice.	EGR1 NFKB1	1.03e-05	2	112	2	25576790
Pubmed	Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.	USP25 SCARB2 RAI1	2.56e-05	18	112	3	21738487
Pubmed	Human 5-, 12- and 15-lipoxygenase-1 coexist in kidney but show opposite trends and their balance changes in cancer.	ALOX12 ALOX5	3.08e-05	3	112	2	22825379
Pubmed	5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.	ALOX12 ALOX5	3.08e-05	3	112	2	18346986
Pubmed	Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.	CLTCL1 CLTC	3.08e-05	3	112	2	19509056
Pubmed	TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.	TSHR TG	3.08e-05	3	112	2	34896620
Pubmed	Analysis of the T cell receptor (TcR) regions in the NOD, NON and CTS mouse strains define new TcR V alpha haplotypes and new deletions in the TcR V beta region.	TRBV12-4 TRBV12-3	3.08e-05	3	112	2	1532150
Pubmed	Targeted knockdown of EGR-1 inhibits IL-8 production and IL-8-mediated invasion of prostate cancer cells through suppressing EGR-1/NF-kappaB synergy.	EGR1 NFKB1	3.08e-05	3	112	2	19837667
Pubmed	Inhibition of Egr-1 by siRNA in prostate carcinoma cell lines is associated with decreased expression of AP-1 and NF-κB.	EGR1 NFKB1	3.08e-05	3	112	2	21743958
Pubmed	5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.	ALOX12 ALOX5	3.08e-05	3	112	2	30407793
Pubmed	Iodinated TG in Thyroid Follicles Regulate TSH/TSHR Signaling for NIS Expression.	TSHR TG	3.08e-05	3	112	2	28396984
Pubmed	Regulatory studies of murine methylenetetrahydrofolate reductase reveal two major promoters and NF-kappaB sensitivity.	CLCN6 NFKB1	3.08e-05	3	112	2	16274753
Pubmed	The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice.	ALOX12 ALOX5	3.08e-05	3	112	2	8944751
Pubmed	The Sp1/Egr1-tandem repeat polymorphism in the 5-lipoxygenase gene promoter is not associated with late onset Alzheimer disease.	EGR1 ALOX5	3.08e-05	3	112	2	18525291
Pubmed	The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors.	EGR1 EGR3	3.08e-05	3	112	2	16287845
Pubmed	Homology between TSH-R/Tg/TPO and Hashimoto's encephalopathy autoantigens.	TSHR TG	3.08e-05	3	112	2	31585887
Pubmed	HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain.	IFT57 HTT	3.08e-05	3	112	2	9140394
Pubmed	Amyloid beta peptide (Abeta42) activates PLC-delta1 promoter through the NF-kappaB binding site.	NFKB1 PLCD1	3.08e-05	3	112	2	14550290
Pubmed	Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles.	PSEN1 ALOX5	3.08e-05	3	112	2	23951061
Pubmed	Epidermal-growth-factor-induced proliferation of astrocytes requires Egr transcription factors.	EGR1 EGR3	3.08e-05	3	112	2	19706684
Pubmed	Overexpression of EGR-1 modulates the activity of NF-κB and AP-1 in prostate carcinoma PC-3 and LNCaP cell lines.	EGR1 NFKB1	3.08e-05	3	112	2	21617851
Pubmed	Early growth response transcriptional regulators are dispensable for macrophage differentiation.	EGR1 EGR3	3.08e-05	3	112	2	17312150
Pubmed	Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase.	ALOX12 ALOX5	3.08e-05	3	112	2	15328042
Pubmed	Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.	AKAP8L HTT	3.08e-05	3	112	2	16391387
Pubmed	Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG.	CLTCL1 CLTC	3.08e-05	3	112	2	22891263
Pubmed	Interleukin-6 upregulates paraoxonase 1 gene expression via an AKT/NF-κB-dependent pathway.	PON1 NFKB1	3.08e-05	3	112	2	23791833
Pubmed	Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration.	CLTCL1 CLTC	3.08e-05	3	112	2	15133132
Pubmed	Relationship of clinical features and laboratory parameters to thyroid echogenicity measured by standardized grey scale ultrasonography in patients with Hashimoto's thyroiditis.	TSHR TG	3.08e-05	3	112	2	12709678
Pubmed	Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability.	ALOX12 ALOX5	3.08e-05	3	112	2	23079635
Pubmed	T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments.	TRBV12-4 TRBV12-3	3.08e-05	3	112	2	3490968
Pubmed	The impact of astrocytic NF-κB on healthy and Alzheimer's disease brains.	PSEN1 NFKB1	3.08e-05	3	112	2	38906984
Pubmed	Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ.	TSHR TG	3.08e-05	3	112	2	27525530
Pubmed	Biological variation of thyroid autoantibodies and thyroglobulin.	TSHR TG	3.08e-05	3	112	2	17902201
Pubmed	Inhibition of arachidonate lipoxygenase12 targets lung cancer through inhibiting EMT and suppressing RhoA and NF-κB activity.	NFKB1 ALOX12	3.08e-05	3	112	2	32037090
Pubmed	Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2.	RHO EOMES UBE3C	4.79e-05	22	112	3	18460603
Pubmed	Functional characterization of genetic enzyme variations in human lipoxygenases.	ALOX12 ALOX5	6.14e-05	4	112	2	24282679
Pubmed	Relationships between protein and mineral during enamel development in normal and genetically altered mice.	AMBN ENAM	6.14e-05	4	112	2	22243238
Pubmed	Identification of 12/15-lipoxygenase as a regulator of axon degeneration through high-content screening.	ALOX12 ALOX5	6.14e-05	4	112	2	25698732
Pubmed	Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific.	RHO CRB1	6.14e-05	4	112	2	25793273
Pubmed	Utility of molecular testing for related retinal dystrophies.	RHO CRB1	6.14e-05	4	112	2	16767206
Pubmed	A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.	F5 DIP2C	6.14e-05	4	112	2	23703922
Pubmed	Human epsilon-sarcoglycan is highly related to alpha-sarcoglycan (adhalin), the limb girdle muscular dystrophy 2D gene.	PON1 SGCE	6.14e-05	4	112	2	9475163
Pubmed	Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter.	EGR1 NFKB1	6.14e-05	4	112	2	18718911
Pubmed	Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice.	ALOX12 ALOX5	6.14e-05	4	112	2	19509298
Pubmed	Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.	IFT57 HTT	6.14e-05	4	112	2	11788820
Pubmed	Novel regulatory action of ribosomal inactivation on epithelial Nod2-linked proinflammatory signals in two convergent ATF3-associated pathways.	EGR1 NFKB1	6.14e-05	4	112	2	24098051
Pubmed	MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3.	TAB3 NFKB1	6.14e-05	4	112	2	24565101
Pubmed	Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.	ALOX12 ALOX5	6.14e-05	4	112	2	20592751
Pubmed	Murine T-cell receptor mutants with deletions of beta-chain variable region genes.	TRBV12-4 TRBV12-3	6.14e-05	4	112	2	3456168
Pubmed	Levels of expression of lipoxygenases and cyclooxygenase-2 in human breast cancer.	ALOX12 ALOX5	6.14e-05	4	112	2	12907138
Pubmed	Genetic analysis of the rhabdomyolysis-associated genes in forensic autopsy cases of methamphetamine abusers.	CPT2 RYR1	6.14e-05	4	112	2	20952238
Pubmed	Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma.	FOXA3 FOXI1	6.14e-05	4	112	2	12695546
Pubmed	An amphioxus Krox gene: insights into vertebrate hindbrain evolution.	EGR1 EGR3	6.14e-05	4	112	2	11180801
Pubmed	Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes.	TRBV12-4 TRBV12-3	6.14e-05	4	112	2	3470773
Pubmed	Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF-kappaB.	EGR1 NFKB1	6.14e-05	4	112	2	17967787
Pubmed	EGR1, EGR2, and EGR3 activate the expression of their coregulator NAB2 establishing a negative feedback loop in cells of neuroectodermal and epithelial origin.	EGR1 EGR3	6.14e-05	4	112	2	20506119
Pubmed	The CCR4-NOT deadenylase activity contributes to generation of induced pluripotent stem cells.	EOMES CNOT7	6.14e-05	4	112	2	27037025
Pubmed	Immediate early genes krox-24 and krox-20 are rapidly up-regulated after wounding in the embryonic and adult mouse.	EGR1 EGR3	6.14e-05	4	112	2	11891986
Pubmed	Iodinated TG in Thyroid Follicular Lumen Regulates TTF-1 and PAX8 Expression via TSH/TSHR Signaling Pathway.	TSHR TG	6.14e-05	4	112	2	28322461
Pubmed	Minireview: thyrotropin receptor signaling in development and differentiation of the thyroid gland: insights from mouse models and human diseases.	TSHR TG	6.14e-05	4	112	2	15231702
Pubmed	Differential roles for ETS, CREB, and EGR binding sites in mediating VEGF receptor 1 expression in vivo.	EGR1 EGR3	6.14e-05	4	112	2	19822898
Pubmed	HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2.	CLTCL1 CLTC	6.14e-05	4	112	2	11517213
GeneFamily	RAB like GTPases	RABL2B RABL2A	1.92e-04	5	80	2	394
GeneFamily	Arachidonate lipoxygenases	ALOX12 ALOX5	2.87e-04	6	80	2	407
Coexpression	GSE15659_NAIVE_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_UP	THEMIS2 CLTCL1 BPIFB6 BCS1L DNAH12 CPNE3 ALOX12 MVB12B	1.81e-06	196	110	8	M3545
Coexpression	GSE15659_CD45RA_NEG_CD4_TCELL_VS_NONSUPPRESSIVE_TCELL_UP	CLTCL1 ATOH7 BPIFB6 BCS1L CPNE3 ALOX12 MVB12B	1.95e-05	196	110	7	M3553
Coexpression	GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_UP	COL17A1 DUSP5 PON1 TDG AKAP8L RYR1 NFKB1	2.22e-05	200	110	7	M5247
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP5 TENM2 NCOR2 CELSR1 PTPN14 EGR1 EGR3	4.63e-07	186	112	7	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PSEN1 DUSP5 HELB PTPN14 EGR1 EGR3 NFKB1	5.94e-07	193	112	7	dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	APOBEC4 BMX A2ML1 CREG2 ALOX5 FOXI1	7.43e-06	185	112	6	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DUSP5 BMX SULT1B1 PTPN14 EGR3 NDRG4	7.43e-06	185	112	6	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DUSP5 BMX SULT1B1 PTPN14 EGR3 NDRG4	8.65e-06	190	112	6	f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PLXDC1 DGKE TNRC6C HELB SLFN12L SAMD3	1.06e-05	197	112	6	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THEMIS2 ABCC4 ACY3 EGR3 ALOX5 LILRA4	1.13e-05	199	112	6	b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RBM11 PLXDC1 DUSP5 TENM2 NCOR2 EXOC6B	1.16e-05	200	112	6	24e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RBM11 PLXDC1 DUSP5 TENM2 NCOR2 EXOC6B	1.16e-05	200	112	6	f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLTCL1 COL17A1 RHO BMX A2ML1	1.68e-05	126	112	5	69b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CLTCL1 COL17A1 RHO BMX A2ML1	1.68e-05	126	112	5	6cb89754010d64875e115da6c5805efac7a4a82d
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMBN CRB1 TG BMX ALOX5	4.26e-05	153	112	5	3b1b0cc8e9dd2b1484649789330713282ee44414
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ACY3 ENAM UMODL1 A2ML1 LILRA4	4.82e-05	157	112	5	62f029831c420d3e9580822177545eb7fdf4d0a3
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACY3 ENAM CELSR1 UMODL1 ALOX12	4.82e-05	157	112	5	d12f343454202da86a06d0369f8ffe5662cd091b
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	STXBP5L GRM7 TENM2 RYR1 CDH8	5.12e-05	159	112	5	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP91 TSHR APOBEC4 RYR1 FOXI1	5.12e-05	159	112	5	00a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCell	LAM-Lymphoid-B-cell-2\|LAM / Condition, Lineage and Cell class	CLDN14 ACY3 DUSP5 TSHR ENAM	5.27e-05	160	112	5	0060c2b3304f411c682aa2ba20bcf80f346d2403
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DUSP5 GRM7 TENM2 CREG2 CDH8	5.43e-05	161	112	5	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PON1 TSHR TNRC6C TRBV12-3 EDEM1	5.59e-05	162	112	5	a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCell	facs-Spleen-nan-3m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP5 PON1 EOMES SAMD3 PEAK1	5.93e-05	164	112	5	a187bd5beca017ef657ef07c006e7f94ea3b911b
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLXDC1 DUSP5 EGR1 EGR3 RAI1	7.23e-05	171	112	5	ea60d9e9df28ab991fbdb596784b44f6a9fc5827
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACY3 TG UMODL1 ALOX12 IL9R	7.43e-05	172	112	5	37ff83f53e99df62691d078ca6801b2c0ec2b123
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLDN14 CRB1 BMX PTPN14 ALOX5	8.06e-05	175	112	5	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLTCL1 TENM2 PTPN14 EGR1 SGCE	8.50e-05	177	112	5	75cb2067a3f2d1b5a964890b02b604d1e79bd163
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	APOBEC4 BMX CREG2 ALOX5 FOXI1	8.73e-05	178	112	5	f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Late_pro-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ENAM UMODL1 CREG2 EDEM1 ALOX5	8.73e-05	178	112	5	4e28a8bd5a603518bfe993712ab785308691b5ff
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-MAIT_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DERL2 EOMES EGR3 PLCD1 SAMD3	8.73e-05	178	112	5	0290868dc990878eac5c182fe64968333bc52450
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKE TDG NCOR2 PTPN14 ALOX12	1.05e-04	185	112	5	60206c7322b4ddb2010040aac70561df842c9843
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFAP91 BMX SULT1B1 UMODL1 NDRG4	1.05e-04	185	112	5	b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CFAP91 BMX SULT1B1 UMODL1 NDRG4	1.05e-04	185	112	5	d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCell	mild-Myeloid-Immature_Neutrophils_1\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CLTCL1 COL17A1 BMX CPNE3 ALOX5	1.05e-04	185	112	5	d747bc91fc276f12a5572ab0223fc71f829a5110
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	DUSP5 BMX SULT1B1 EGR3 NDRG4	1.07e-04	186	112	5	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_Cytotoxic_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DUSP5 EOMES EGR1 NFKB1 SAMD3	1.13e-04	188	112	5	c80956649b10b7dd7540394a00fc2a0619b27e80
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	USF3 EGR3 SAMD3 HTT IL9R	1.13e-04	188	112	5	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	DUSP5 BMX SULT1B1 PTPN14 NDRG4	1.16e-04	189	112	5	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP5 TENM2 NCOR2 CELSR1 PTPN14	1.16e-04	189	112	5	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|lymph-node_spleen / Manually curated celltypes from each tissue	DAB2IP EOMES SLFN12L SAMD3 MVB12B	1.16e-04	189	112	5	e8ff2c4fd2481bfbc99a5a6f02e0db8c995b3a23
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DAB2IP TNRC6C EOMES SLFN12L SAMD3	1.19e-04	190	112	5	05e6af222d0ad97cb69f399a96c9038f9dd989b9
ToppCell	PBMC-Severe-Myeloid-Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL17A1 BMX EGR1 EGR3 ALOX5	1.19e-04	190	112	5	fedd266198d294d8da8c9e217e5e0cb8b2e1b566
ToppCell	COVID-19_Severe-Myeloid_G\|COVID-19_Severe / Disease group, lineage and cell class	COL17A1 BMX EGR1 EGR3 ALOX5	1.19e-04	190	112	5	8a81cb90273c361e9fdfaa0a31806da253fa1388
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	ABCC4 BMX SULT1B1 EGR1 NDRG4	1.22e-04	191	112	5	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	PBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMEM214 TSHR ENAM SCARB2 EDEM1	1.22e-04	191	112	5	dd1d38a531a272a746c16807688013d29cab823a
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL17A1 DUSP5 TENM2 NCOR2 PTPN14	1.22e-04	191	112	5	2f733d510a4862565a817f59829d8387d7ea26d9
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL17A1 DUSP5 TENM2 NCOR2 PTPN14	1.22e-04	191	112	5	8691eba35793e4e90f93d50c2145847ee51289f7
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HELB PTPN14 EGR1 EGR3 NFKB1	1.25e-04	192	112	5	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	ASK452-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP91 IFT57 RABL2B RABL2A DNAH12	1.28e-04	193	112	5	c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 CLDN14 DUSP5 TSHR ENAM	1.28e-04	193	112	5	5c5543e7c83ecea44d23521246592c0301044173
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 CLDN14 DUSP5 TSHR ENAM	1.34e-04	195	112	5	0b0615553b9a1b60d666d074ce4260919e2d5642
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AMBN F5 STPG2 BMX EGR1	1.34e-04	195	112	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AMBN F5 STPG2 BMX EGR1	1.34e-04	195	112	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	COVID_vent-Myeloid-Monocytic-Developing_Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CLTCL1 COL17A1 BMX CPNE3 ALOX5	1.34e-04	195	112	5	de23409b1b4146b8ae286850b829ec8dceed0117
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THEMIS2 PLXDC1 RYR1 ALOX5 MVB12B	1.34e-04	195	112	5	42bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytotoxic_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DAB2IP DUSP5 EOMES SAMD3 MVB12B	1.34e-04	195	112	5	730c613cf6f4d16ca51fd44de1f5a883f615c5c5
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP91 APOBEC4 RABL2B RABL2A DNAH12	1.37e-04	196	112	5	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP91 APOBEC4 RABL2B RABL2A DNAH12	1.37e-04	196	112	5	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	Parenchyma_Control_(B.)-Immune-TX-T_cells\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	DUSP5 HELB EOMES SLFN12L SAMD3	1.40e-04	197	112	5	3712eaa1d2ed200e0b0fdb2886f4cdf641fd2cdc
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 CLDN14 DUSP5 TSHR ENAM	1.40e-04	197	112	5	749e0e332644543cbdf2ee38c2b301ce0a019a7f
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PLAAT1 NKRF UMODL1 CREG2 FOXI1	1.40e-04	197	112	5	fd76cc5e12c7e7943a48f739e4f0626ff7211f51
ToppCell	Lung_Parenchyma-Control-Lymphocyte-T/NK-Other_T-T_cells\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DUSP5 HELB EOMES SLFN12L SAMD3	1.40e-04	197	112	5	7effa80fa97a97906a9e8e8d00513bebfef0f980
ToppCell	Lung_Parenchyma-Control-Lymphocyte-T/NK\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DUSP5 HELB EOMES SLFN12L SAMD3	1.40e-04	197	112	5	185e9a6bd9894a050604a1af66c2fc39cf1f8d7a
ToppCell	Lung_Parenchyma-Control-Lymphocyte-T/NK-Other_T-T_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DUSP5 HELB EOMES SLFN12L SAMD3	1.40e-04	197	112	5	af96ef0dbf89d4a2b78f48a1e1182b719025d67c
ToppCell	Lung_Parenchyma-Control-Lymphocyte-T/NK-Other_T\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DUSP5 HELB EOMES SLFN12L SAMD3	1.40e-04	197	112	5	6153f14a457c0b8452729aa301e5486a539e9cba
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP91 APOBEC4 RABL2B RABL2A DNAH12	1.44e-04	198	112	5	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 CLDN14 DUSP5 ENAM ALOX5	1.47e-04	199	112	5	1bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCell	medial-Endothelial-Artery\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DAB2IP BMX PTPN14 EGR1 NDRG4	1.47e-04	199	112	5	341c0be18bec66f4cc8bda232dce54edb34b9cda
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 CLDN14 DUSP5 ENAM ALOX5	1.47e-04	199	112	5	2f60682f1b82918a65e8851e99c9e3398845b62f
ToppCell	medial-2-Endothelial-Artery\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DAB2IP BMX PTPN14 EGR1 NDRG4	1.47e-04	199	112	5	53c17c0493f82351a039bc64def191311e0f4951
ToppCell	medial-Endothelial-Artery-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DAB2IP BMX PTPN14 EGR1 NDRG4	1.47e-04	199	112	5	c455f5a2802f2ec6f0e24266de1aaf3203ca8c78
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 CLDN14 DUSP5 ENAM ALOX5	1.47e-04	199	112	5	58242d78517c05fa367a7c6edac57ef79107453c
ToppCell	(10)_Ciliated\|World / shred by cell type by condition	CFAP91 IFT57 RABL2B RABL2A DNAH12	1.51e-04	200	112	5	1b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	THEMIS2 DUSP5 EOMES SLFN12L SAMD3	1.51e-04	200	112	5	5ad680b0e36428e485a4256a9d0ae70dcb80115e
ToppCell	(09)_Interm._secr.>cil.\|World / shred by cell type by condition	CFAP91 IFT57 RABL2B RABL2A DNAH12	1.51e-04	200	112	5	3305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCell	Control-Control-Lymphocyte-T/NK-MAIT\|Control / Disease, condition lineage and cell class	DAB2IP TNRC6C EOMES SLFN12L SAMD3	1.51e-04	200	112	5	888a8045e0457cd9d0c570360cca20a6efb44f13
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLTCL1 COL17A1 RHO BMX	1.90e-04	113	112	4	b795a0c65114b3c0758fe3720e8a80247f900971
Drug	epichlorohydrin triethanolamine	F5 RHO TG	4.37e-07	4	110	3	CID000163191
Drug	AC1L1IPS	CLTCL1 TG CLTC	2.17e-06	6	110	3	CID000004682
Drug	sodium linoleate	ACACA ACY3 PON1 DGKE CPT2 NCOR2 SCARB2 NFKB1 ALOX12 ALOX5	6.37e-06	342	110	10	CID000003931
Disease	Depressive disorder	PSEN1 PON1 GRM7 TG EGR3 SGCE MAP2K5 HTT	8.78e-06	289	104	8	C0011581
Disease	Autoimmune thyroiditis	TSHR TG	7.35e-05	4	104	2	C0920350
Disease	Amelogenesis imperfecta type 1	AMBN ENAM	1.22e-04	5	104	2	cv:C0399367
Disease	Membranoproliferative Glomerulonephritis, Type I	PON1 DGKE	1.83e-04	6	104	2	C0268742
Disease	Membranoproliferative Glomerulonephritis, Type III	PON1 DGKE	1.83e-04	6	104	2	C1720821
Disease	Amelogenesis imperfecta local hypoplastic form	AMBN ENAM	2.55e-04	7	104	2	C0399367
Disease	hereditary lymphedema (is_implicated_in)	PIEZO1 CELSR1	2.55e-04	7	104	2	DOID:0050580 (is_implicated_in)
Disease	retinal vein occlusion (is_implicated_in)	PON1 F5	2.55e-04	7	104	2	DOID:1727 (is_implicated_in)
Disease	uric acid measurement	CLDN14 TSHR F5 TENM2 CRB1 NDC1 NFKB1 DIP2C MTX1	3.13e-04	610	104	9	EFO_0004761
Disease	cystic fibrosis (implicated_via_orthology)	ABCC4 EDEM1	4.36e-04	9	104	2	DOID:1485 (implicated_via_orthology)
Disease	Hyperthyroidism	PON1 TSHR	4.36e-04	9	104	2	C0020550
Disease	Primary Hyperthyroidism	PON1 TSHR	4.36e-04	9	104	2	C3714618
Disease	Anxiety States, Neurotic	TG EOMES RAI1	5.07e-04	44	104	3	C0376280
Disease	Anxiety neurosis (finding)	TG EOMES RAI1	5.07e-04	44	104	3	C1279420
Disease	Anxiety Disorders	TG EOMES RAI1	5.07e-04	44	104	3	C0003469
Disease	glucagon-like peptide-1 measurement	AMBN ENAM	5.44e-04	10	104	2	EFO_0008465
Disease	WNT1-inducible-signaling pathway protein 1 measurement	SLC46A1 TG	5.44e-04	10	104	2	EFO_0008321
Disease	Hyperhomocysteinemia	PON1 SLC46A1	6.63e-04	11	104	2	C0598608
Disease	Complications of Diabetes Mellitus	ABCC4 PON1	6.63e-04	11	104	2	C0342257
Disease	Amelogenesis Imperfecta	COL17A1 ENAM	7.94e-04	12	104	2	C0002452
Disease	Congenital Hypothyroidism	TSHR TG	9.36e-04	13	104	2	C0010308
Disease	unipolar depression, mood disorder, response to antidepressant	NDC1 CDH8	1.09e-03	14	104	2	EFO_0003761, EFO_0004247, GO_0036276
Disease	congenital hypothyroidism (implicated_via_orthology)	TSHR TG	1.09e-03	14	104	2	DOID:0050328 (implicated_via_orthology)
Disease	3-hydroxyanthranilic acid measurement	TG CREG2	1.25e-03	15	104	2	EFO_0010447
Disease	Brain Ischemia	F5 EGR1 NFKB1	1.26e-03	60	104	3	C0007786
Disease	Cerebral Ischemia	F5 EGR1 NFKB1	1.26e-03	60	104	3	C0917798
Disease	Amelogenesis imperfecta	AMBN ENAM	1.62e-03	17	104	2	cv:C0002452
Disease	basophil percentage of leukocytes	RYR1 HELB RSBN1 ZDHHC6 NFKB1	1.72e-03	243	104	5	EFO_0007992
Disease	Colonic Neoplasms	F5 EOMES NFKB1 ALOX5	2.09e-03	152	104	4	C0009375
Disease	Mental Depression	PSEN1 GRM7 EGR3 SGCE HTT	2.09e-03	254	104	5	C0011570
Disease	eosinophil count	THEMIS2 FOXA3 RBCK1 TG EOMES NCOR2 SLFN12L CELSR1 NFKB1 PEAK1 FER1L5 RAI1 IL9R	2.21e-03	1488	104	13	EFO_0004842
Disease	Malignant tumor of colon	F5 EOMES NFKB1 ALOX5	2.46e-03	159	104	4	C0007102
Disease	Alcoholic Intoxication, Chronic	SLC46A1 GRM7 NFKB1 SGCE CDH8	2.64e-03	268	104	5	C0001973
Disease	pulmonary hypertension (biomarker_via_orthology)	RYR1 EGR1 ALOX5	2.87e-03	80	104	3	DOID:6432 (biomarker_via_orthology)
Disease	airway responsiveness measurement	ABCC4 USP24	3.23e-03	24	104	2	EFO_0006897
Disease	response to mTOR inhibitor	STPG2 MVB12B	3.50e-03	25	104	2	EFO_0005417
Disease	Deafness	CLDN14 FOXI1	3.50e-03	25	104	2	C0011053

Protein segments in the cluster

Peptide	Gene	Start	Entry
MQLFIGDSPIPQNYS	UMODL1	1116	Q5DID0
AFYTFPFQQLMAEAP	TDG	16	Q13569
LMDFFQTYGAIQGPP	COL17A1	1426	Q9UMD9
MFPFLSFNINGLNPT	EOMES	296	O95936
MDLGTFYREFQNPPQ	ATG13	461	O75143
LAAQLQMLFSNFPDP	ALG1	416	Q9BT22
DFQPLQPGAPIFQMF	ACY3	251	Q96HD9
MLYVPFGANQLNAPA	AMBN	241	Q9NP70
YPLNNAFPGQFFQMP	APOBEC4	261	Q8WW27
SQPNFNMQYIPREDF	BMX	226	P51813
LTQMFQRFYPGQAPS	BCS1L	361	Q9Y276
FQQDTLPNVPGMYTL	A2ML1	1286	A8K2U0
FPMNFNPSNPYCNGI	CPNE3	361	O75131
VNVMNGYCLPDPFFS	ACACA	861	Q13085
GSLKFPMPNYQVALF	CELSR1	241	Q9NYQ6
DGPFNNSTGIPFFYM	CREG2	161	Q8IUH2
LFSQNIIPEYGMFQG	AKAP8L	221	Q9ULX6
FERPFLPFFQQMPFN	CFAP91	146	Q7Z4T9
SVVLNFNPFMAFNPD	CPT2	126	P23786
SPLMPNLENFPYSQQ	RAI1	361	Q7Z5J4
SFPMQYFPINNTSLP	RBM11	121	P57052
MNGTEGPNFYVPFSN	RHO	1	P08100
AYNFCVPGDQMNPEF	PCDHGB7	751	Q9Y5F8
FLMDGFQPQQLSTYA	RABL2A	41	Q9UBK7
FLMDGFQPQQLSTYA	RABL2B	41	Q9UNT1
TDPRLNTPMYFFLGN	OR9K2	76	Q8NGE7
LSFQNPVYQMAAGLP	DAB2IP	826	Q5VWQ8
YNISQPGTEIFNMPA	NCOR2	2301	Q9Y618
NSLYPATLNFMKGFP	SLC46A1	411	Q96NT5
FQALFPMGPLTFSNR	LILRA4	176	P59901
DMVFLDYGFPPVLQQ	RBCK1	86	Q9BYM8
YEAPLMPCGFIFQFQ	KATNIP	1391	O60303
FIYMDPVFNTEPNPN	FRMD7	416	Q6ZUT3
GFQVPMIPDYLFPQQ	EGR1	246	P18146
TENDIYNFFSPLNPM	HNRNPH2	301	P55795
FMELALGRFPYPQIQ	MAP2K5	346	Q13163
TVFNTPNLNTPMYFL	OR4K17	51	Q8NGC6
PNLNTPMYFLLGNLS	OR4K17	56	Q8NGC6
NDPQLHIPMYFFLGS	OR5H2	56	Q8NGV7
NSYNNAGMPPFPIII	PEAK1	596	Q9H792
NPNCFVAITMNPGYA	DNAH12	1346	Q6ZR08
TLQVYGFPVNQLFDM	EXOC6B	411	Q9Y2D4
ELFSYQFLNGANPML	ALOX12	226	P18054
QAPPQYTFIGELNSM	MVB12B	171	Q9H7P6
ALNFQTPGPEMDVYQ	PLCD1	576	P51178
IIFDNVNFMYSPGGP	ABCC4	1041	O15439
QLGLTFMNEQGEYPP	CNOT7	76	Q9UIV1
PNDTYNDMATLFFNP	CLCN6	431	P51797
FLSNQQPYPQFMATV	HTT	3001	P42858
LPTNPGEQFYMFCTL	IFT57	76	Q9NWB7
NFYNPLLPSGMKFEI	CLDN14	146	O95500
PALDSNLFPMIPDYN	EGR3	181	Q06889
YSQRLFGFQPEPFQM	ATOH7	136	Q8N100
LVFPNNDPAAFMAAF	DIP2C	386	Q9Y2E4
QVGLPLPDFLAMNYN	BPIFB6	421	Q8NFQ5
DPPLYVNVNMFSGQL	EDEM1	416	Q92611
QQAALPQMPLFENFY	MIDEAS	261	Q6PJG2
PSDFNGLPMGTYQAF	IST1	251	P53990
PENFNEAKPIGFTMY	GRM7	781	Q14831
SEGYMPVPNFNSVDQ	ENAM	476	Q9NRM1
PEMNLYYENFFHPQG	FOXI1	26	Q12951
FLYSLLPEMVNNPNF	CDH8	531	P55286
NNYFSVGPDALMALN	DGKE	371	P52429
MNFFGLLNFQAPFLP	DERL2	141	Q9GZP9
ALLNFYNMPSTPSFV	CRB1	626	P82279
MPVAFLEPQLNEYNA	RYR1	3201	P21817
SPNFGFMGQLLQYES	DUSP5	301	Q16690
VQGFPSYFLQSDMSP	HELB	106	Q8NG08
FIPAMQDNYALTFGN	FAM166A	286	Q6J272
SDPRLQNPMYFFLSI	OR1L3	51	Q8NH93
NMFYFFPPLQILAEN	OR10R2	11	Q8NGX6
AMIIFNLSSYNPGPF	OR52H1	6	Q8NGJ2
IQLLFMYQIPFCGPN	OR4C6	156	Q8NH72
YAEAMPFPLNFFLPG	MTX1	276	Q13505
LDYFAFNFPNTPVKM	RSBN1	426	Q5VWQ0
TFAPYPLAGLNPNMN	TNRC6C	1261	Q9HCJ0
PNGMKIFFYDSENPP	PON1	286	P27169
MTELPAPLSYFQNAQ	PSEN1	1	P49768
VAATPNYNPFFMNEQ	TAB3	131	Q8N5C8
QEFNESFPYPDLGQM	F5	1476	P12259
YQPNTLDPIFGMMFE	FER1L5	1526	A0AVI2
LMFGYQFLNGCNPVL	ALOX5	231	P09917
QPVTANMYFDSGNPA	NKRF	126	O15226
MPSFYPAENLDNGLI	SAMD3	106	Q8N6K7
APYNFNHPFSINNLM	FOXA3	296	P55318
NEPLLFFGVMFYVPN	PTPN14	91	Q15678
ELGSPLYNNEPFAIM	STRIP1	251	Q5VSL9
NGAPIIMSFPHFYQA	SCARB2	331	Q14108
EPAPFNLYMFKSNNP	TENM2	2451	Q9NT68
GASQFPQGYQFPSME	NDRG4	76	Q9ULP0
FYQNVPSPAMFFQPL	IL9R	301	Q01113
SNDPITFNTNLMGYP	SGCE	81	O43556
FPLPYQAEFFIKNMN	SGCE	156	O43556
YHFDLMNNLQPFPGT	SULT1B1	141	O43704
LTQSNFPIFENPYPM	STXBP5L	391	Q9Y2K9
FFPPEAQNDFPVAMQ	CLTC	251	Q00610
FFPPEAQNDFPVAMQ	CLTCL1	251	P53675
NYFNAMFVGPGFVPL	ZDHHC6	71	Q9H6R6
PFVPNFLDFMQNGNY	SLFN12L	106	Q6IEE8
MPGPGFYNVLNNTII	STPG2	256	Q8N412
MELAPNFQGYFTPLN	THEMIS2	71	Q5TEJ8
FPLLDFAYMPNNSLT	TMEM214	321	Q6NUQ4
FAYMPNNSLTPSLQE	TMEM214	326	Q6NUQ4
NTEMFGQYPLQVNGF	USP25	316	Q9UHP3
IYFNNNVPIDDSGMP	TRBV12-3	66	P01733
LSNDISIPYFPNQMF	USF3	2121	Q68DE3
MAFNDCFSLNYPGNP	PLAAT1	1	Q9HDD0
IYFNNNVPIDDSGMP	TRBV12-4	66	A0A0B4J2E0
NAVFQQLYMQPGLPE	USP24	1701	Q9UPU5
LGGYEPLFTMSAQQP	PIEZO1	2216	Q92508
QFDPQPLAMQFISQY	PIEZO1	2246	Q92508
ATQYVAPLMANFNPG	PLXDC1	171	Q8IUK5
APLMANFNPGYSDNS	PLXDC1	176	Q8IUK5
GFQNMLSGLYNPIVF	TG	1696	P01266
YPNPAAQMLVGDSFA	UBE3C	801	Q15386
NPYMTSIPVNAFQGL	TSHR	161	P16473
SLLYFVNNMNYLPFP	NDC1	181	Q9BTX1
FQPQMALPTDGPYLQ	NFKB1	31	P19838