Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K36me/H3K36me2 demethylase activity

KDM2A KDM2B

1.35e-064102GO:0140680
GeneOntologyMolecularFunctionunmethylated CpG binding

KDM2A KDM2B

1.01e-0510102GO:0045322
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

KDM2A KDM2B

1.24e-0511102GO:0051864
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM2A KDM2B

8.47e-0528102GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM2A KDM2B

1.04e-0431102GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM2A KDM2B

1.11e-0432102GO:0140457
GeneOntologyMolecularFunctiondemethylase activity

KDM2A KDM2B

2.11e-0444102GO:0032451
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM2A KDM2B

4.62e-0465102GO:0016706
GeneOntologyMolecularFunctiondioxygenase activity

KDM2A KDM2B

1.05e-0398102GO:0051213
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

KDM2A KDM2B

4.01e-03194102GO:0016705
GeneOntologyMolecularFunctionhistone modifying activity

KDM2A KDM2B

5.55e-03229102GO:0140993
GeneOntologyBiologicalProcessprotein demethylation

KDM2A KDM2B

7.60e-061092GO:0006482
GeneOntologyBiologicalProcessprotein dealkylation

KDM2A KDM2B

7.60e-061092GO:0008214
GeneOntologyBiologicalProcessregionalization

KDM2A NKX3-2 KDM2B NKX3-1

3.27e-0547894GO:0003002
GeneOntologyBiologicalProcessdemethylation

KDM2A KDM2B

4.65e-052492GO:0070988
GeneOntologyBiologicalProcesspattern specification process

KDM2A NKX3-2 KDM2B NKX3-1

4.76e-0552694GO:0007389
GeneOntologyBiologicalProcessembryonic organ morphogenesis

KDM2A NKX3-2 KDM2B

3.80e-0435193GO:0048562
GeneOntologyBiologicalProcesschordate embryonic development

KDM2A NKX3-2 KDM2B NKX3-1

3.90e-0490694GO:0043009
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

KDM2A NKX3-2 KDM2B NKX3-1

4.30e-0492994GO:0009792
GeneOntologyBiologicalProcesspositive regulation of intrinsic apoptotic signaling pathway

ADCY10 NKX3-1

4.74e-047692GO:2001244
GeneOntologyBiologicalProcessepithelial tube morphogenesis

KDM2A KDM2B NKX3-1

6.47e-0442193GO:0060562
GeneOntologyBiologicalProcessneural tube closure

KDM2A KDM2B

1.04e-0311392GO:0001843
GeneOntologyBiologicalProcesstube closure

KDM2A KDM2B

1.06e-0311492GO:0060606
GeneOntologyBiologicalProcessprimary neural tube formation

KDM2A KDM2B

1.18e-0312092GO:0014020
GeneOntologyBiologicalProcessmembrane depolarization

ADCY10 CNGA2

1.20e-0312192GO:0051899
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

ADCY10 OAZ3 KDM2B NKX3-1

1.26e-03123594GO:0003006
GeneOntologyBiologicalProcessanimal organ morphogenesis

KDM2A NKX3-2 KDM2B NKX3-1

1.40e-03126994GO:0009887
GeneOntologyBiologicalProcessneural tube formation

KDM2A KDM2B

1.46e-0313492GO:0001841
GeneOntologyBiologicalProcessembryonic organ development

KDM2A NKX3-2 KDM2B

1.49e-0356193GO:0048568
GeneOntologyBiologicalProcessdetermination of left/right symmetry

KDM2A NKX3-2

1.93e-0315492GO:0007368
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

KDM2A KDM2B NKX3-1

1.97e-0361993GO:0002009
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

KDM2A NKX3-2 KDM2B NKX3-1

2.01e-03139994GO:0045892
GeneOntologyBiologicalProcesstube development

KDM2A NKX3-2 KDM2B NKX3-1

2.03e-03140294GO:0035295
GeneOntologyBiologicalProcessembryonic epithelial tube formation

KDM2A KDM2B

2.05e-0315992GO:0001838
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

KDM2A NKX3-2 KDM2B NKX3-1

2.09e-03141394GO:1902679
GeneOntologyBiologicalProcessleft/right pattern formation

KDM2A NKX3-2

2.13e-0316292GO:0060972
GeneOntologyBiologicalProcesscolumnar/cuboidal epithelial cell differentiation

KDM2A NKX3-2

2.18e-0316492GO:0002065
GeneOntologyBiologicalProcessdetermination of bilateral symmetry

KDM2A NKX3-2

2.21e-0316592GO:0009855
GeneOntologyBiologicalProcessspecification of symmetry

KDM2A NKX3-2

2.21e-0316592GO:0009799
GeneOntologyBiologicalProcessembryo development

KDM2A NKX3-2 KDM2B NKX3-1

2.22e-03143794GO:0009790
GeneOntologyBiologicalProcessepithelium development

KDM2A NKX3-2 KDM2B NKX3-1

2.41e-03146994GO:0060429
GeneOntologyBiologicalProcessepithelial tube formation

KDM2A KDM2B

2.42e-0317392GO:0072175
GeneOntologyBiologicalProcesspositive regulation of apoptotic signaling pathway

ADCY10 NKX3-1

2.45e-0317492GO:2001235
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

KDM2A NKX3-2 KDM2B NKX3-1

2.50e-03148394GO:0048646
GeneOntologyBiologicalProcesstube formation

KDM2A KDM2B

2.82e-0318792GO:0035148
GeneOntologyBiologicalProcessmorphogenesis of embryonic epithelium

KDM2A KDM2B

2.91e-0319092GO:0016331
GeneOntologyBiologicalProcessembryonic morphogenesis

KDM2A NKX3-2 KDM2B

2.96e-0371393GO:0048598
GeneOntologyBiologicalProcesssensory organ development

XRN2 NKX3-2 KDM2B

3.16e-0373093GO:0007423
GeneOntologyBiologicalProcessneural tube development

KDM2A KDM2B

3.28e-0320292GO:0021915
GeneOntologyBiologicalProcessspermatogenesis

ADCY10 OAZ3 KDM2B

3.34e-0374493GO:0007283
GeneOntologyBiologicalProcesstissue morphogenesis

KDM2A KDM2B NKX3-1

3.41e-0375093GO:0048729
GeneOntologyBiologicalProcessmale gamete generation

ADCY10 OAZ3 KDM2B

3.57e-0376293GO:0048232
GeneOntologyBiologicalProcesspositive regulation of cell growth

ADCY10 KDM2B

3.64e-0321392GO:0030307
GeneOntologyBiologicalProcessregulation of intrinsic apoptotic signaling pathway

ADCY10 NKX3-1

3.74e-0321692GO:2001242
GeneOntologyBiologicalProcessanterior/posterior pattern specification

KDM2B NKX3-1

4.86e-0324792GO:0009952
MousePhenoabnormal neuron proliferation

KDM2A KDM2B

1.70e-039892MP:0009967
MousePhenoincreased embryonic tissue cell apoptosis

KDM2A KDM2B

4.07e-0315392MP:0013504
MousePhenoabnormal neuron physiology

KDM2A KDM2B CNGA2

5.55e-0360493MP:0004811
MousePhenoabnormal embryonic tissue cell apoptosis

KDM2A KDM2B

5.59e-0318092MP:0013503
MousePhenoabnormal cell proliferation

KDM2A NKX3-2 KDM2B NKX3-1

6.29e-03129494MP:0000350
DomainPHD_4

KDM2A KDM2B

7.74e-073102PF16866
Domainzf-CXXC

KDM2A KDM2B

1.42e-0511102PF02008
DomainZF_CXXC

KDM2A KDM2B

1.42e-0511102PS51058
DomainZnf_CXXC

KDM2A KDM2B

1.42e-0511102IPR002857
DomainLeu-rich_rpt_Cys-con_subtyp

KDM2A KDM2B

4.39e-0519102IPR006553
DomainLRR_CC

KDM2A KDM2B

4.39e-0519102SM00367
DomainJmjC

KDM2A KDM2B

7.08e-0524102PF02373
DomainJMJC

KDM2A KDM2B

1.27e-0432102PS51184
DomainJmjC_dom

KDM2A KDM2B

1.27e-0432102IPR003347
DomainJmjC

KDM2A KDM2B

1.35e-0433102SM00558
DomainFBOX

KDM2A KDM2B

3.37e-0452102SM00256
DomainF-box

KDM2A KDM2B

5.60e-0467102PF00646
DomainHTH_motif

NKX3-2 NKX3-1

5.94e-0469102IPR000047
DomainFBOX

KDM2A KDM2B

6.46e-0472102PS50181
DomainF-box_dom

KDM2A KDM2B

7.01e-0475102IPR001810
DomainZnf_PHD-finger

KDM2A KDM2B

7.78e-0479102IPR019787
DomainPHD

KDM2A KDM2B

9.86e-0489102SM00249
DomainHomeobox_metazoa

NKX3-2 NKX3-1

1.01e-0390102IPR020479
DomainZnf_PHD

KDM2A KDM2B

1.03e-0391102IPR001965
DomainZF_PHD_2

KDM2A KDM2B

1.12e-0395102PS50016
DomainZF_PHD_1

KDM2A KDM2B

1.15e-0396102PS01359
DomainZnf_FYVE_PHD

KDM2A KDM2B

2.66e-03147102IPR011011
DomainHomeobox_CS

NKX3-2 NKX3-1

4.21e-03186102IPR017970
DomainHomeobox

NKX3-2 NKX3-1

6.58e-03234102PF00046
DomainHOMEOBOX_1

NKX3-2 NKX3-1

6.69e-03236102PS00027
DomainHOX

NKX3-2 NKX3-1

6.75e-03237102SM00389
DomainHomeobox_dom

NKX3-2 NKX3-1

6.86e-03239102IPR001356
DomainHOMEOBOX_2

NKX3-2 NKX3-1

6.86e-03239102PS50071
Domain-

NKX3-2 NKX3-1

9.50e-032831021.10.10.60
Domain-

KDM2A KDM2B

1.21e-023211023.80.10.10
DomainL_dom-like

KDM2A KDM2B

1.26e-02328102IPR032675
DomainHomeodomain-like

NKX3-2 NKX3-1

1.29e-02332102IPR009057
Domain-

KDM2A KDM2B

2.28e-024491023.30.40.10
DomainZnf_RING/FYVE/PHD

KDM2A KDM2B

2.38e-02459102IPR013083
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM2A KDM2B

1.46e-042992MM14934
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM2A KDM2B

4.37e-045092M27232
Pubmed

Biological Functions of the KDM2 Family of Histone Demethylases.

KDM2A KDM2B

7.44e-08210237751135
Pubmed

Expression of an Nkx3.1-CRE gene using ROSA26 reporter mice.

NKX3-2 NKX3-1

7.44e-08210217078065
Pubmed

KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity.

KDM2A KDM2B

7.44e-08210231363749
Pubmed

Combined expression levels of KDM2A and KDM2B correlate with nucleolar size and prognosis in primary breast carcinomas.

KDM2A KDM2B

7.44e-08210232901907
Pubmed

Transcription factors Nkx3.1 and Nkx3.2 (Bapx1) play an overlapping role in sclerotomal development of the mouse.

NKX3-2 NKX3-1

7.44e-08210212204261
Pubmed

Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin.

KDM2A KDM2B

2.23e-07310226004508
Pubmed

A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.

KDM2A KDM2B

2.23e-07310230033217
Pubmed

Histone demethylation by a family of JmjC domain-containing proteins.

KDM2A KDM2B

4.46e-07410216362057
Pubmed

Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome.

NKX3-2 NKX3-1

1.12e-06610212490554
Pubmed

Vertebrate homologs of tinman and bagpipe: roles of the homeobox genes in cardiovascular development.

NKX3-2 NKX3-1

1.12e-0661029621431
Pubmed

Sequence and chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia.

NKX3-2 NKX3-1

2.68e-0691029344671
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

KDM2A KDM2B

3.34e-061010229276034
Pubmed

Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly.

KDM2A KDM2B

6.76e-061410221220025
Pubmed

SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins.

KDM2A KDM2B

6.76e-061410217463251
Pubmed

Deletion of the sclerotome-enriched lncRNA PEAT augments ribosomal protein expression.

NKX3-2 NKX3-1

7.80e-061510227986952
Pubmed

The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators.

KDM2A KDM2B

7.80e-061510225463925
Pubmed

Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation.

NKX3-2 NKX3-1

8.91e-061610217477400
Pubmed

The histone H3K36 demethylase Fbxl11 plays pivotal roles in the development of retinal late-born cell types.

KDM2A KDM2B

1.41e-052010237073980
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM2A KDM2B

1.56e-052110227626377
Pubmed

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

KDM2A KDM2B

4.15e-053410230894540
Pubmed

A family of mammalian F-box proteins.

KDM2A KDM2B

6.37e-054210210531037
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM2A KDM2B

8.69e-054910234368113
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM2A KDM2B

1.18e-045710218022353
Pubmed

A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.

KDM2A KDM2B

1.31e-046010220682791
Pubmed

Systematic analysis and nomenclature of mammalian F-box proteins.

KDM2A KDM2B

1.35e-046110215520277
GeneFamilyZinc fingers CXXC-type

KDM2A KDM2B

6.05e-061262136
GeneFamilyF-box and leucine rich repeat proteins

KDM2A KDM2B

1.92e-052162558
GeneFamilyPHD finger proteins|Lysine demethylases

KDM2A KDM2B

2.52e-052462485
GeneFamilyNKL subclass homeoboxes and pseudogenes

NKX3-2 NKX3-1

2.01e-046762519
GeneFamilyPHD finger proteins

KDM2A KDM2B

3.63e-04906288
CoexpressionGSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_HET_DN

ADCY10 OAZ3 NKX3-1

4.54e-05193103M8725
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Adora1_(Striatum,_interneuron)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADCY10 CNGA2

9.47e-0566102d6b202d9f5bebaac23b34b689ad306549dec0593
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Adora1_(Striatum,_interneuron)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADCY10 CNGA2

9.47e-05661024a714cf035b22da103054098f85f9170c56e9e83
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6_(Thalamus,_glutamatergic)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NKX3-1 CNGA2

1.19e-04741026ecbdf4186039a031410e09ecd5afa66b6d5e2dc
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6_(Thalamus,_glutamatergic)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NKX3-1 CNGA2

1.19e-0474102ef4c9eafc794c7d50aef28b37d21b52d3c511499
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADCY10 NKX3-1

1.29e-0477102a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NKX3-2 CNGA2

1.72e-04891022e5da863e68a8fe378a34b67e4703013b731a7a4
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NKX3-2 CNGA2

1.72e-0489102a4c2e364f8017dd9631f5ef06bdabdb2ebed1db8
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NKX3-2 CNGA2

1.72e-0489102c9c3fce307f14e90cc0d24e9611c454010a60869
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Zbtb20_(Ventral_Hippocampus)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADCY10 NKX3-1

2.63e-0411010246635a130453c2fa304f0e09561b2a267c9ceb31
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADCY10 NKX3-1

2.63e-041101023639fb5fc02eca509cb220295bc3e6064c23baab
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADCY10 NKX3-1

2.63e-04110102438bf761ab0a25e3dc9244c23ae2c2d68a169c7f
ToppCellEntopeduncular-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Zbtb20_(Ventral_Hippocampus)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADCY10 NKX3-1

2.63e-04110102ff196c71aa2a21cdd812958bd163fa6b91bd2352
ToppCellTCGA-Prostate|World / Sample_Type by Project: Shred V9

OAZ3 NKX3-1

3.29e-0412310222b38555652b7a426a6277ed385361ae275310a3
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VOPP1 KDM2B

5.01e-0415210287a7116d0064a6051bdf28ce1e48bfc168273e66
ToppCell18-Airway-Epithelial-Goblet-like_secretory|Airway / Age, Tissue, Lineage and Cell class

OAZ3 NKX3-1

5.08e-0415310214a60220e169ce642771636de982a7b02e5b2608
ToppCell368C-Myeloid-Dendritic-cDC_activated|368C / Donor, Lineage, Cell class and subclass (all cells)

VOPP1 KDM2B

5.55e-04160102bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VOPP1 NKX3-2

5.90e-04165102c042cde64b61ae195e1054f7b560151dabbfdf0d
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VOPP1 KDM2B

5.97e-0416610275d719617c61409860f298ce91cbe3a0aafa0553
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VOPP1 KDM2B

5.97e-04166102da10d0be6b616199d49dd922591c2901f9681583
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VOPP1 KDM2B

6.12e-041681026dd58fd981750da49afd53796f244e1803cce97f
ToppCell(7)_MNP-(7)_DC_activated|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ADCY10 KDM2B

6.26e-041701024ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

VOPP1 KDM2B

6.33e-04171102ce290930385cac35dbd21a5e91cf0f93cf3e99f8
ToppCellfacs-Heart-RV-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX3-2 LMBR1L

6.41e-04172102d061ea21bee179df5a525842e9a48621a8e1461b
ToppCell367C-Myeloid-Dendritic-cDC_activated|367C / Donor, Lineage, Cell class and subclass (all cells)

VOPP1 KDM2B

6.48e-0417310294f99f7e7813d6e53e0bedf97087400b1bf00129
ToppCellwk_15-18-Hematologic-Myeloid-aDC_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

VOPP1 KDM2B

6.78e-04177102ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCell367C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

VOPP1 KDM2B

6.78e-04177102a0ff337f11bdb11959ac71805ff94be6b4ec1083
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

6.78e-04177102aa56129d2d5a73a10e33b7162233a4d9337ee535
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

VOPP1 KDM2B

6.78e-04177102370aee11a6dc2c6f4366a13c3171f37bc5b32d65
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

6.78e-0417710270ca5b6fde2e38af1eb88a7d6e8746edba298191
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

6.78e-04177102d78a6003ce2d15d7771ae385de252eec7e3c3eea
ToppCelldroplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAZ3 NKX3-1

7.01e-04180102b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCellwk_20-22-Hematologic-Myeloid-aDC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

VOPP1 KDM2B

7.09e-041811028f7e5c310f4cdc4b2fb54fea950d01e56bd298e1
ToppCellCOPD-Myeloid-DC_Mature|World / Disease state, Lineage and Cell class

VOPP1 KDM2B

7.09e-04181102675603a401d92cf9fdcd44e211ec899fa86a0d49
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VOPP1 KDM2B

7.25e-04183102e01dacb08a9c36cf09c0b6764ce032a7232d4cdc
ToppCell(7)_DC_activated|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ADCY10 KDM2B

7.33e-04184102b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

VOPP1 KDM2B

7.41e-041851027e3d9f5050e71e91021245c11101e994ae41d22b
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|normal_Lung / Location, Cell class and cell subclass

VOPP1 KDM2B

7.48e-041861020987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCellIPF-Myeloid-DC_Mature|IPF / Disease state, Lineage and Cell class

VOPP1 KDM2B

7.56e-0418710263e0304a0183b69aebb0d1a4640a506a0d6fb6e9
ToppCellCOPD-Myeloid-DC_Mature|COPD / Disease state, Lineage and Cell class

VOPP1 KDM2B

7.65e-04188102de93ccb53edb8599da9e312db0e3af604c21f673
ToppCell(3)_DC_activated|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

VOPP1 KDM2B

7.73e-04189102e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

7.81e-041901025175bf022d55a52988014abe7cece326a8406a38
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

7.81e-0419010229e60b9b1c86b44550619c01306b8b1bb2e340dc
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

7.81e-041901022ff4b50b864a35f22c558d7d585cd2b54612b50c
ToppCell(3)_MNP-(3)_DC_activated|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

VOPP1 KDM2B

7.89e-041911020353bf797c4ef237b9bb82460c173c7d03cb8883
ToppCell367C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

VOPP1 KDM2B

7.97e-04192102e44e37e5aeba8628556020d05e1606b28e2faa4f
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

VOPP1 KDM2B

8.05e-04193102024d30eb143d8278c0851c3a6c9426226fa3b480
ToppCellPBMC-Control-cDC_5|Control / Compartment, Disease Groups and Clusters

VOPP1 LMBR1L

8.05e-0419310253ddee444dcfb9fe568e9e8fb64bc8304c262530
ToppCellILEUM-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

VOPP1 KDM2B

8.05e-04193102d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

VOPP1 KDM2B

8.14e-0419410230f683725cb13ae32ef6846618801ec78e12397d
ToppCelltumor_Lung-Myeloid_cells-Activated_DCs|tumor_Lung / Location, Cell class and cell subclass

VOPP1 KDM2B

8.14e-04194102a85d958aff84f2296c330a7dcd442bd2344738df
ToppCelltumor_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

VOPP1 KDM2B

8.22e-0419510272a7c4beb880390b29f3c5d6dd9dbb082af50fe2
ToppCell390C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

VOPP1 KDM2B

8.22e-04195102ecf7d9856a5b507ec17c325c9a772dc5a184bc8e
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

8.39e-041971022a140c61e81aa18de2c9c1c443e314d6f09cdc18
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

8.39e-04197102fa3fe934bd5fd8c6520a9c46357f9e441c794aba
ToppCellCOVID-19-Myeloid-Migratory_DC|COVID-19 / Condition, Lineage and Cell class

VOPP1 KDM2B

8.39e-04197102b6d6cdae33753c1e38394f1f879e00b87f9c0496
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VOPP1 KDM2B

8.39e-0419710232eb4437cc608b8369e376446d639497ecfdd17a
ToppCell390C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

VOPP1 KDM2B

8.39e-04197102311438418f3d697e54222da111014c887fd815f5
ToppCellBronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VOPP1 KDM2B

8.39e-0419710268d8546dfe7dffd017756a11d3333061f576d0ef
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VOPP1 KDM2B

8.56e-0419910282759af613ebfffe037afda55159bf6af812c3ac
ToppCell390C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

VOPP1 KDM2B

8.64e-042001023935b6ff3ae32d170a268538c756ee34ed2308d4
DrugPuromycin dihydrochloride [58-58-2]; Up 200; 7.4uM; MCF7; HT_HG-U133A

KDM2A OAZ3 NKX3-1

4.56e-051681035310_UP
DrugQuipazine dimaleate salt [4774-24-7]; Up 200; 9uM; MCF7; HT_HG-U133A

NKX3-2 ADCY10 LMBR1L

7.21e-051961037240_UP
DrugSulfathiazole [72-14-0]; Down 200; 15.6uM; MCF7; HT_HG-U133A

NKX3-2 LMBR1L NKX3-1

7.32e-051971031463_DN

Protein segments in the cluster

PeptideGeneStartEntry
WRIYSYSYLFHCKYY

ADCY10

1216

Q96PN6
YPIWSPYAYYLYCYK

OAZ3

26

Q9UMX2
YYYPYYCLPGWALST

NKX3-2

311

P78367
YPFYYEMCWYVLERY

KDM2A

326

Q9Y2K7
YPFYYEMCWYVLERY

KDM2B

356

Q8NHM5
LYDFWEYYLPYLYSC

LMBR1L

186

Q6UX01
SYPYYPYLYCVGSWS

NKX3-1

216

Q99801
EYGYLAREYIYCLYW

CNGA2

316

Q16280
CWYFEGLYPTYYICR

VOPP1

26

Q96AW1
RYYYQGCASWKWYYP

XRN2

551

Q9H0D6