Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD2 RANBP2 RGPD3

2.24e-0720544GO:0061665
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RGPD2 RANBP2 RGPD3

2.64e-0636544GO:0019789
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RGPD2 RANBP2 RGPD3

1.00e-0550544GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RGPD2 RANBP2 RGPD3

1.27e-0553544GO:0016859
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

SETD2 NSD2 MECOM METTL22

3.42e-0568544GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

SETD2 NSD2 MECOM METTL22

3.62e-0569544GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

SETD2 NSD2 MECOM METTL22

4.06e-0571544GO:0042054
GeneOntologyMolecularFunctionhistone H3K36 trimethyltransferase activity

SETD2 NSD2

7.14e-055542GO:0140955
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

SETD2 NSD2 MECOM METTL22 DNMT3B

1.01e-04172545GO:0008757
GeneOntologyMolecularFunctionprotein methyltransferase activity

SETD2 NSD2 MECOM METTL22

1.73e-04103544GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

SETD2 NSD2 MECOM METTL22

1.87e-04105544GO:0008170
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 RGPD2 RANBP2 ABCA1 RGPD3 ARFIP2

2.22e-04321546GO:0031267
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

SETD2 NSD2 MECOM

2.29e-0444543GO:0140938
GeneOntologyMolecularFunctionmethyltransferase activity

SETD2 NSD2 MECOM METTL22 DNMT3B

2.72e-04213545GO:0008168
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

SETD2 NSD2 MECOM METTL22 DNMT3B

3.44e-04224545GO:0016741
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

ABCC4 KCNAB2 AKR1B15 ME1

3.86e-04127544GO:0016616
GeneOntologyMolecularFunctionGTPase binding

RGPD4 RGPD2 RANBP2 ABCA1 RGPD3 ARFIP2

4.10e-04360546GO:0051020
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

ABCC4 KCNAB2 AKR1B15 ME1

5.28e-04138544GO:0016614
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

SETD2 NSD2

5.49e-0413542GO:0046975
GeneOntologyMolecularFunctionGTP binding

ARFRP1 ADSS2 SEPTIN9 GNA15 RAB39B ARFIP2

6.86e-04397546GO:0005525
GeneOntologyMolecularFunctionprotein-folding chaperone binding

DNAJB1 AGO2 AHSA2P DNAJB5

9.41e-04161544GO:0051087
GeneOntologyMolecularFunctionoxidoreductase activity

CYP4Z2P ABCC4 PLOD3 CYP4Z1 KCNAB2 AIFM3 AKR1B15 ME1

9.86e-04766548GO:0016491
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

ARFRP1 ADSS2 SEPTIN9 GNA15 RAB39B ARFIP2

1.15e-03439546GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

ARFRP1 ADSS2 SEPTIN9 GNA15 RAB39B ARFIP2

1.15e-03439546GO:0019001
GeneOntologyMolecularFunctionisomerase activity

RGPD4 RGPD2 RANBP2 RGPD3

1.80e-03192544GO:0016853
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

KCNAB2 AKR1B15

3.38e-0332542GO:0004033
GeneOntologyMolecularFunctionATPase activator activity

DNAJB1 AHSA2P

3.38e-0332542GO:0001671
GeneOntologyMolecularFunctionhistone modifying activity

SETD2 NSD2 MECOM METTL22

3.40e-03229544GO:0140993
GeneOntologyMolecularFunctiontranscription corepressor activity

DNAJB1 MAP3K10 COPS2 DNMT3B

3.40e-03229544GO:0003714
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RGPD4 RGPD2 RANBP2 RGPD3 TRIM50

4.35e-03398545GO:0061659
GeneOntologyMolecularFunctionbHLH transcription factor binding

MAP3K10 SMAD3

4.50e-0337542GO:0043425
GeneOntologyMolecularFunctionunfolded protein binding

DNAJB1 CHAF1B DNAJB5

4.81e-03126543GO:0051082
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD2 RANBP2 RGPD3

4.85e-099534GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RGPD2 RANBP2 RGPD3

8.06e-0910534GO:1903301
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RGPD2 RANBP2 RGPD3

2.73e-0813534GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RGPD2 RANBP2 RGPD3

3.81e-0814534GO:1903299
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RGPD2 RANBP2 RGPD3

1.83e-0720534GO:0006607
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RGPD2 RANBP2 RGPD3

2.69e-0638534GO:0000413
GeneOntologyBiologicalProcessprotein folding

RGPD4 DNAJB1 RGPD2 RANBP2 RGPD3 AHSA2P DNAJB5

3.04e-06246537GO:0006457
GeneOntologyBiologicalProcessnuclear export

RGPD4 RGPD2 RANBP2 SETD2 RBM10 RGPD3

7.77e-06185536GO:0051168
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RGPD2 RANBP2 RGPD3

1.12e-0554534GO:0018208
GeneOntologyBiologicalProcessregulation of gluconeogenesis

RGPD4 RGPD2 RANBP2 RGPD3

3.32e-0571534GO:0006111
GeneOntologyBiologicalProcessmRNA transport

RGPD4 RGPD2 RANBP2 SETD2 RGPD3

3.50e-05145535GO:0051028
GeneOntologyBiologicalProcessnucleobase-containing compound transport

RGPD4 RGPD2 RANBP2 SETD2 ABCC4 RGPD3

4.16e-05249536GO:0015931
GeneOntologyBiologicalProcessnuclear transport

RGPD4 RGPD2 RANBP2 SETD2 RBM10 RGPD3 SMAD3

4.90e-05378537GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

RGPD4 RGPD2 RANBP2 SETD2 RBM10 RGPD3 SMAD3

4.90e-05378537GO:0006913
GeneOntologyBiologicalProcesspericardium development

SETD2 MECOM SMAD3

5.01e-0528533GO:0060039
GeneOntologyBiologicalProcessRNA transport

RGPD4 RGPD2 RANBP2 SETD2 RGPD3

8.57e-05175535GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

RGPD4 RGPD2 RANBP2 SETD2 RGPD3

8.57e-05175535GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

RGPD4 RGPD2 RANBP2 SETD2 RGPD3

9.28e-05178535GO:0051236
GeneOntologyBiologicalProcessprotein import into nucleus

RGPD4 RGPD2 RANBP2 RGPD3 SMAD3

1.42e-04195535GO:0006606
GeneOntologyBiologicalProcessimport into nucleus

RGPD4 RGPD2 RANBP2 RGPD3 SMAD3

1.64e-04201535GO:0051170
GeneOntologyBiologicalProcessprotein maturation

RGPD4 DNAJB1 RGPD2 RANBP2 RGPD3 AHSA2P DNAJB5 GSN

1.69e-04619538GO:0051604
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

DNAJB1 ZNF469 NSD2 RBM10 PDX1 MAP3K10 MECOM NOSTRIN DNAJB5 COPS2 SMAD3 DNMT3B

1.78e-0413995312GO:0045892
GeneOntologyBiologicalProcessgluconeogenesis

RGPD4 RGPD2 RANBP2 RGPD3

1.90e-04111534GO:0006094
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

DNAJB1 ZNF469 NSD2 RBM10 PDX1 MAP3K10 MECOM NOSTRIN DNAJB5 COPS2 SMAD3 DNMT3B

1.96e-0414135312GO:1902679
GeneOntologyBiologicalProcesshexose biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD3

2.17e-04115534GO:0019319
GeneOntologyBiologicalProcessRNA localization

RGPD4 RGPD2 RANBP2 SETD2 RGPD3

2.34e-04217535GO:0006403
GeneOntologyBiologicalProcessmonosaccharide biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD3

2.64e-04121534GO:0046364
GeneOntologyBiologicalProcessmethylation

SETD2 NSD2 MECOM METTL22 DNMT3B

3.32e-04234535GO:0032259
GeneOntologyBiologicalProcesstransdifferentiation

PDX1 SMAD3

3.51e-0411532GO:0060290
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD3

3.68e-04132534GO:0043255
GeneOntologyBiologicalProcessregulation of glucose metabolic process

RGPD4 RGPD2 RANBP2 RGPD3

3.90e-04134534GO:0010906
GeneOntologyBiologicalProcessglucose metabolic process

RGPD4 RGPD2 RANBP2 RGPD3 PDX1

4.02e-04244535GO:0006006
GeneOntologyBiologicalProcessregulation of ribonucleoprotein complex localization

SETD2 RBM10

4.96e-0413532GO:2000197
GeneOntologyBiologicalProcesspositive regulation of non-motile cilium assembly

TTBK2 SEPTIN9

4.96e-0413532GO:1902857
GeneOntologyBiologicalProcessintracellular protein transport

RGPD4 RGPD2 RANBP2 ARFRP1 STXBP2 RGPD3 ARFIP2 SMAD3

5.61e-04740538GO:0006886
GeneOntologyBiologicalProcessribonucleoprotein complex localization

SETD2 RBM10

5.78e-0414532GO:0071166
GeneOntologyBiologicalProcesshexose metabolic process

RGPD4 RGPD2 RANBP2 RGPD3 PDX1

7.99e-04284535GO:0019318
GeneOntologyBiologicalProcessregulation of non-motile cilium assembly

TTBK2 SEPTIN9

9.65e-0418532GO:1902855
GeneOntologyBiologicalProcessmonosaccharide metabolic process

RGPD4 RGPD2 RANBP2 RGPD3 PDX1

1.18e-03310535GO:0005996
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD2 RANBP2 RGPD3

2.76e-098544GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD2 RANBP2 RGPD3

8.25e-0910544GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD2 RANBP2 RGPD3

3.90e-0814544GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RGPD2 RANBP2 RGPD3

1.18e-0718544GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RGPD2 RANBP2 RGPD3

1.87e-0720544GO:0042405
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RGPD2 RANBP2 RGPD3

2.30e-0721544GO:0106068
GeneOntologyCellularComponentinclusion body

RGPD4 RGPD2 RANBP2 RGPD3 TRIM50

3.54e-0690545GO:0016234
GeneOntologyCellularComponentnuclear pore

RGPD4 RGPD2 RANBP2 RGPD3

1.35e-04101544GO:0005643
GeneOntologyCellularComponentnuclear membrane

RGPD4 RGPD2 RANBP2 RGPD3 SMAD3

2.04e-03349545GO:0031965
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RGPD2 RANBP2 RGPD3

2.16e-0716484MP:0003701
MousePhenoabnormal morula morphology

RGPD4 RGPD2 RANBP2 RGPD3

1.73e-0626484MP:0012058
MousePhenodecreased tumor latency

RGPD4 RGPD2 RANBP2 RGPD3

3.14e-0630484MP:0010308
MousePhenofailure of blastocyst formation

RGPD4 RGPD2 RANBP2 RGPD3

3.60e-0631484MP:0012129
MousePhenoabnormal tumor latency

RGPD4 RGPD2 RANBP2 RGPD3

5.26e-0634484MP:0010307
MousePhenoabnormal blastocyst formation

RGPD4 RGPD2 RANBP2 RGPD3

9.21e-0639484MP:0012128
MousePhenoaneuploidy

RGPD4 RGPD2 RANBP2 RGPD3

5.53e-0561484MP:0004024
MousePhenoincreased hepatocellular carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD3

9.50e-0570484MP:0003331
MousePhenoincreased incidence of tumors by chemical induction

RGPD4 RGPD2 RANBP2 RGPD3 AKR1B15

1.17e-04141485MP:0004499
MousePhenoincreased lung carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD3

1.45e-0478484MP:0008714
MousePhenoabnormal chromosome number

RGPD4 RGPD2 RANBP2 RGPD3

2.11e-0486484MP:0004023
MousePhenoabnormal preimplantation embryo development

RGPD4 RGPD2 RANBP2 PLOD3 RGPD3

2.89e-04171485MP:0009781
MousePhenoincreased incidence of induced tumors

RGPD4 RGPD2 RANBP2 RGPD3 AKR1B15

3.05e-04173485MP:0002021
MousePhenoenlarged epididymis

RGPD4 RGPD2 RANBP2 RGPD3

3.63e-0499484MP:0004931
MousePhenoincreased sarcoma incidence

RGPD4 RGPD2 RANBP2 RGPD3

4.06e-04102484MP:0002032
MousePhenoincreased physiological sensitivity to xenobiotic

RGPD4 RGPD2 RANBP2 RGPD3 AKR1B15 ARFIP2

4.15e-04286486MP:0008873
MousePhenoincreased lung tumor incidence

RGPD4 RGPD2 RANBP2 RGPD3

4.87e-04107484MP:0008014
MousePhenofailure of blastocyst to hatch from the zona pellucida

RGPD4 RGPD2 RANBP2 RGPD3

4.87e-04107484MP:0003694
MousePhenoincreased respiratory system tumor incidence

RGPD4 RGPD2 RANBP2 RGPD3

4.87e-04107484MP:0010298
MousePhenoincreased carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD3 SMAD3

5.53e-04197485MP:0002038
MousePhenoincreased liver tumor incidence

RGPD4 RGPD2 RANBP2 RGPD3

5.60e-04111484MP:0008019
MousePhenoincreased hepatobiliary system tumor incidence

RGPD4 RGPD2 RANBP2 RGPD3

5.60e-04111484MP:0010297
MousePhenoabnormal blastocyst hatching

RGPD4 RGPD2 RANBP2 RGPD3

5.99e-04113484MP:0003693
MousePhenoabnormal rod electrophysiology

RGPD4 RGPD2 RANBP2 RGPD3

7.28e-04119484MP:0004021
MousePhenoabnormal extraembryonic tissue morphology

SLC25A3 SETD2 ABCA1 AGO2 PLOD3 ARFRP1 ARID3A MECOM COPS2 DNMT3B

8.66e-049084810MP:0002086
MousePhenoabnormal chromosome morphology

RGPD4 RGPD2 RANBP2 RGPD3

9.01e-04126484MP:0003702
MousePhenoabnormal mitosis

RGPD4 RGPD2 RANBP2 RGPD3

9.56e-04128484MP:0004046
DomainRan_BP1

RGPD4 RGPD2 RANBP2 RGPD3

2.60e-0812524PF00638
DomainRANBD1

RGPD4 RGPD2 RANBP2 RGPD3

2.60e-0812524PS50196
DomainRanBD

RGPD4 RGPD2 RANBP2 RGPD3

3.75e-0813524SM00160
DomainRan_bind_dom

RGPD4 RGPD2 RANBP2 RGPD3

3.75e-0813524IPR000156
DomainGCC2_Rab_bind

RGPD4 RGPD2 RGPD3

7.07e-077523IPR032023
DomainRab_bind

RGPD4 RGPD2 RGPD3

7.07e-077523PF16704
Domain-

RGPD4 RGPD2 RGPD3

2.41e-06105231.10.220.60
DomainGrip

RGPD4 RGPD2 RGPD3

3.31e-0611523SM00755
DomainGRIP

RGPD4 RGPD2 RGPD3

3.31e-0611523PF01465
DomainGRIP_dom

RGPD4 RGPD2 RGPD3

4.40e-0612523IPR000237
DomainGRIP

RGPD4 RGPD2 RGPD3

4.40e-0612523PS50913
DomainAWS

SETD2 NSD2

7.56e-055522SM00570
DomainAWS

SETD2 NSD2

7.56e-055522PS51215
DomainAWS_dom

SETD2 NSD2

7.56e-055522IPR006560
DomainDnaJ_C

DNAJB1 DNAJB5

2.70e-049522IPR002939
DomainDnaJ_C

DNAJB1 DNAJB5

2.70e-049522PF01556
DomainHSP40/DnaJ_pept-bd

DNAJB1 DNAJB5

2.70e-049522IPR008971
Domain-

RGPD4 RGPD2 RANBP2 RGPD3 COPS2

2.71e-042075251.25.40.10
DomainTPR

RGPD4 RGPD2 RANBP2 RGPD3

4.55e-04129524SM00028
DomainTPR-like_helical_dom

RGPD4 RGPD2 RANBP2 RGPD3 COPS2

4.67e-04233525IPR011990
DomainTPR_repeat

RGPD4 RGPD2 RANBP2 RGPD3

5.11e-04133524IPR019734
DomainTPR-contain_dom

RGPD4 RGPD2 RANBP2 RGPD3

8.02e-04150524IPR013026
DomainPost-SET_dom

SETD2 NSD2

8.90e-0416522IPR003616
DomainPostSET

SETD2 NSD2

8.90e-0416522SM00508
Domain-

KCNAB2 AKR1B15

8.90e-04165223.20.20.100
DomainPOST_SET

SETD2 NSD2

8.90e-0416522PS50868
DomainNADP_OxRdtase_dom

KCNAB2 AKR1B15

1.01e-0317522IPR023210
DomainAldo_ket_red

KCNAB2 AKR1B15

1.01e-0317522PF00248
DomainAldo/ket_red/Kv-b

KCNAB2 AKR1B15

1.01e-0317522IPR001395
DomainTPR_REGION

RGPD4 RGPD2 RANBP2 RGPD3

1.14e-03165524PS50293
DomainTPR

RGPD4 RGPD2 RANBP2 RGPD3

1.14e-03165524PS50005
DomainPWWP

NSD2 DNMT3B

1.40e-0320522SM00293
Domainzf-RanBP

RANBP2 RBM10

1.69e-0322522PF00641
DomainPWWP

NSD2 DNMT3B

1.85e-0323522PF00855
DomainZnF_RBZ

RANBP2 RBM10

1.85e-0323522SM00547
DomainPWWP_dom

NSD2 DNMT3B

1.85e-0323522IPR000313
DomainZF_RANBP2_2

RANBP2 RBM10

1.85e-0323522PS50199
DomainPWWP

NSD2 DNMT3B

2.02e-0324522PS50812
DomainZF_RANBP2_1

RANBP2 RBM10

2.02e-0324522PS01358
DomainZnf_RanBP2

RANBP2 RBM10

2.19e-0325522IPR001876
DomainP-loop_NTPase

ABCC4 ABCA1 ARFRP1 ADSS2 STARD9 SEPTIN9 GNA15 RAB39B

2.23e-03848528IPR027417
DomainDnaJ_domain_CS

DNAJB1 DNAJB5

2.55e-0327522IPR018253
DomainSET

SETD2 NSD2

5.82e-0341522PF00856
DomainABC_transporter_CS

ABCC4 ABCA1

6.10e-0342522IPR017871
DomainSET

SETD2 NSD2

7.28e-0346522SM00317
DomainDnaJ

DNAJB1 DNAJB5

7.90e-0348522PF00226
DomainABC_tran

ABCC4 ABCA1

7.90e-0348522PF00005
DomainABC_TRANSPORTER_2

ABCC4 ABCA1

7.90e-0348522PS50893
DomainABC_TRANSPORTER_1

ABCC4 ABCA1

8.22e-0349522PS00211
DomainDNAJ_1

DNAJB1 DNAJB5

8.22e-0349522PS00636
DomainDNAJ_2

DNAJB1 DNAJB5

8.22e-0349522PS50076
DomainDnaJ

DNAJB1 DNAJB5

8.22e-0349522SM00271
Domain-

DNAJB1 DNAJB5

8.22e-03495221.10.287.110
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RGPD2 RANBP2 AGO2 RGPD3

1.43e-0741435MM15200
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RGPD2 RANBP2 RGPD3

2.23e-0718434MM1549
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RGPD2 RANBP2 AGO2 RGPD3

3.59e-0749435MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RGPD2 RANBP2 RGPD3 CPSF2

3.98e-0750435MM14610
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 DNAJB1 RGPD2 RANBP2 RGPD3

2.68e-0673435MM14948
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RGPD2 RANBP2 RGPD3 CPSF2

6.03e-0686435MM15413
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RGPD2 RANBP2 RGPD3

6.33e-0640434MM14945
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD3

7.72e-0642434MM15039
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 DNAJB1 RGPD2 RANBP2 RGPD3

8.40e-0692435MM14951
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RGPD2 RANBP2 RGPD3

8.49e-0643434MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD3

1.22e-0547434MM14939
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD3

1.69e-0551434MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RGPD2 RANBP2 RGPD3

2.29e-0555434MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD3

2.82e-0558434MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RGPD2 RANBP2 RGPD3

2.82e-0558434MM14736
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD3

4.44e-0565434MM15147
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RGPD2 RANBP2 RGPD3

1.10e-0482434MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD3

1.21e-0484434MM14929
PathwayREACTOME_SUMOYLATION

RGPD4 RGPD2 RANBP2 RGPD3 DNMT3B

1.55e-04169435MM14919
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

RGPD4 RGPD2 RANBP2 RBM10 RGPD3 CPSF2

1.80e-04277436MM15414
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

RGPD4 RGPD2 RANBP2 RGPD3

2.38e-04100434MM14561
PathwayKEGG_LYSINE_DEGRADATION

SETD2 PLOD3 NSD2

3.21e-0444433M13720
PathwayREACTOME_MITOTIC_PROPHASE

RGPD4 RGPD2 RANBP2 RGPD3

3.93e-04114434MM15361
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

RGPD4 RGPD2 RANBP2 RGPD3

4.33e-04117434MM15387
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

RGPD4 RGPD2 RANBP2 RGPD3

6.27e-04129434MM14894
PathwayREACTOME_RHO_GTPASES_ACTIVATE_FORMINS

RGPD4 RGPD2 RANBP2 RGPD3

8.74e-04141434MM15266
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

SETD2 NSD2 MECOM

1.26e-0370433M27231
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

RGPD4 RGPD2 RANBP2 NSD2 RGPD3

1.34e-03271435MM15388
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754421205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754418949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754425187515
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-1075449037092
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-1075448603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754426632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754424403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754423818861
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754411353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754430944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754438838144
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754423536549
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-1075447559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754417372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754438657106
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754412191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754422821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RGPD2 RANBP2 RGPD3

1.81e-10754420682751
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RGPD2 RANBP2 RGPD3

3.62e-10854422262462
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RGPD2 RANBP2 RGPD3

3.62e-10854421670213
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RGPD2 RANBP2 RGPD3

3.62e-10854428745977
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RGPD2 RANBP2 RGPD3

3.62e-10854427412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RGPD2 RANBP2 RGPD3

3.62e-10854421310149
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD2 RANBP2 RGPD3

6.50e-10954418394993
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RGPD2 RANBP2 RGPD3

6.50e-10954411553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RGPD2 RANBP2 RGPD3

6.50e-10954410601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RGPD2 RANBP2 RGPD3

6.50e-1095449733766
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RGPD2 RANBP2 RGPD3

6.50e-10954428100513
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RGPD2 RANBP2 RGPD3

6.50e-10954428877029
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RGPD2 RANBP2 RGPD3

6.50e-10954417887960
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RGPD2 RANBP2 RGPD3

1.08e-09105448857542
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RGPD2 RANBP2 RGPD3

1.08e-091054427160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RGPD2 RANBP2 RGPD3

1.08e-091054416332688
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RGPD2 RANBP2 RGPD3

1.08e-091054421859863
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RGPD2 RANBP2 RGPD3

1.70e-091154435771867
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RGPD2 RANBP2 RGPD3

1.70e-091154417069463
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RGPD2 RANBP2 RGPD3

1.70e-091154434110283
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RGPD2 RANBP2 RGPD3

3.67e-091354431427429
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RGPD2 RANBP2 RGPD3

6.99e-091554414697343
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

SLC25A3 RGPD4 DNAJB1 RGPD2 RANBP2 ARID3A RBM10 RGPD3 ZCCHC17 CPSF2 SMAD3

8.99e-09701541130196744
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RGPD2 RANBP2 RGPD3

3.72e-082254427717094
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD2 RGPD3

1.23e-07754315710750
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

RGPD4 RGPD2 RANBP2 NSD2 RGPD3

2.36e-078654537253089
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RGPD2 RANBP2 RGPD3

3.68e-073854412791264
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RGPD4 RGPD2 RANBP2 GAS2L3 NSD2 RGPD3 GSN

1.68e-0637054722922362
Pubmed

Hsc40, a new member of the hsp40 family, exhibits similar expression profile to that of hsc70 in mammalian cells.

DNAJB1 DNAJB5

2.37e-06254210570961
Pubmed

The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1.

CYP4Z2P CYP4Z1

2.37e-06254225701119
Pubmed

The competing endogenous RNA network of CYP4Z1 and pseudogene CYP4Z2P exerts an anti-apoptotic function in breast cancer.

CYP4Z2P CYP4Z1

2.37e-06254228236635
Pubmed

Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma.

CYP4Z2P CYP4Z1

2.37e-06254215059886
Pubmed

The miRISC component AGO2 has multiple binding sites for Nup358 SUMO-interacting motif.

RANBP2 AGO2

2.37e-06254233838501
Pubmed

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3.

MECOM SMAD3

2.37e-0625429665135
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

RGPD4 RGPD2 RANBP2 CHAF1B RGPD3

4.10e-0615354526365490
Pubmed

ABC transporters as differentiation markers in glioblastoma cells.

ABCC4 ABCA1

7.09e-06354225028266
Pubmed

The COP9 signalosome controls ubiquitinylation of ABCA1.

ABCA1 COPS2

7.09e-06354219268428
Pubmed

The oncoprotein EVI1 and the DNA methyltransferase Dnmt3 co-operate in binding and de novo methylation of target DNA.

MECOM DNMT3B

7.09e-06354221695170
Pubmed

Rbm10 regulates inflammation development via alternative splicing of Dnmt3b.

RBM10 DNMT3B

7.09e-06354229309623
Pubmed

Apolipoprotein A-1 binding protein promotes macrophage cholesterol efflux by facilitating apolipoprotein A-1 binding to ABCA1 and preventing ABCA1 degradation.

ABCA1 COPS2

7.09e-06354227017521
Pubmed

Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells.

CYP4Z2P CYP4Z1

7.09e-06354230832689
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RGPD4 RGPD2 RANBP2 TRNT1 STXBP2 NSD2 STARD9 RGPD3 RAB39B NOSTRIN DNMT3B

1.11e-051442541135575683
Pubmed

Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP.

MECOM SMAD3

1.42e-05454215897867
Pubmed

Small RNAs Recruit Chromatin-Modifying Enzymes MMSET and Tip60 to Reconfigure Damaged DNA upon Double-Strand Break and Facilitate Repair.

AGO2 NSD2

1.42e-05454226822153
Pubmed

Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.

RGPD4 RGPD2 RANBP2 RGPD3

1.75e-059954427746211
Pubmed

Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation.

SETD2 NSD2

2.36e-05554239390582
Pubmed

TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway.

TTBK2 AGO2

2.36e-05554228219405
Pubmed

Mixed lineage kinase 2 enhances trans-repression of Alien and nuclear receptors.

MAP3K10 COPS2

2.36e-05554215062575
Pubmed

A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation.

SETD2 NSD2

2.36e-05554233135541
Pubmed

Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development.

SMAD3 DNMT3B

2.36e-05554229637597
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

DNAJB1 RANBP2 CHAF1B SETD2 TRNT1 ADSS2 NSD2 CPSF2 COPS2

2.40e-05101454932416067
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SLC25A3 RANBP2 CHAF1B STXBP2 GAS2L3 RBM10 SEPTIN9 CPSF2 GSN

2.60e-05102454924711643
Pubmed

Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.

SETD2 NSD2

3.54e-05654224019522
Pubmed

Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1.

MECOM SMAD3

3.54e-05654215849193
Pubmed

The corepressor activity of Alien is controlled by CREB-binding protein/p300.

MAP3K10 COPS2

4.94e-05754223441852
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

SLC25A3 RGPD4 RANBP2 GAS2L3 SEPTIN9 RGPD3 GSN

5.03e-0562654733644029
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

RGPD4 RGPD2 RANBP2 RGPD3

5.91e-0513554431077711
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

SLC25A3 RGPD4 DNAJB1 RGPD2 TTBK2 RANBP2 GSN

6.19e-0564754726618866
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

DNAJB1 RANBP2 STXBP2 RBM10 SEPTIN9 AMOTL1 COPS2 ME1 GSN

6.34e-05114954935446349
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

RGPD4 RGPD2 RANBP2 PLOD3 RBM10 RGPD3 COPS2

7.35e-0566554730457570
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

RGPD4 RGPD2 RANBP2 RGPD3

8.01e-0514654423892456
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 RGPD2 RANBP2 AGO2 RGPD3 KCNAB2 CPSF2 GSN

1.13e-0496354828671696
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SLC25A3 RANBP2 CHAF1B SETD2 NSD2 RBM10 RGPD3 MECOM CPSF2

1.56e-04129454930804502
Pubmed

Smad signaling pathways regulate pancreatic endocrine development.

PDX1 SMAD3

1.83e-041354223603491
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SLC25A3 DNAJB1 SETD2 AGO2 RBM10 AMOTL1

2.05e-0454954638280479
Pubmed

A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.

NSD2 DNMT3B

2.13e-041454226912663
Pubmed

Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells.

PDX1 SMAD3

2.13e-041454215277382
Pubmed

DNA cloning using in vitro site-specific recombination.

TRNT1 RBM10 AMOTL1 PDX1 MAP3K10 RAB39B DNMT3B

2.19e-0479454711076863
Pubmed

Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase.

COPS2 DNMT3B

2.45e-041554229691401
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SLC25A3 RANBP2 SETD2 NSD2 RBM10 ZCCHC17 CPSF2 DNMT3B

2.50e-04108254838697112
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

SLC25A3 ABCA1 AGO2 ARID3A PDX1

2.77e-0437154515747579
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD4 DNAJB1 RGPD2 TTBK2 RANBP2 RGPD3 COPS2 SMAD3

3.87e-04115554820360068
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

RGPD4 RGPD2 RANBP2 RGPD3

4.26e-0422654437839992
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

SLC25A3 DNAJB1 RANBP2 ARID3A DNMT3B

4.42e-0441154535182466
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

RGPD4 RGPD2 RANBP2 RGPD3

4.62e-0423154416452087
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 RGPD2 RANBP2 RGPD3 MECOM

4.77e-0441854534709266
Pubmed

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.

NSD2 RBM10

4.88e-042154224923560
Pubmed

Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.

DNAJB1 DNAJB5

5.36e-042254211147971
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

AGO2 STARD9 AMOTL1 KCNAB2 CPSF2

5.42e-0443054532581705
Pubmed

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.

DNAJB1 DNAJB5

5.86e-042354221231916
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

SLC25A3 RANBP2 AGO2 PLOD3 ADSS2 SEPTIN9 ME1 SMAD3

6.42e-04124754827684187
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

SLC25A3 RGPD4 DNAJB1 RGPD2 RANBP2 AGO2 RGPD3 CPSF2

6.76e-04125754837317656
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

ADSS2 GAS2L3 SEPTIN9 AMOTL1 TRIM50 SMAD3

6.81e-0468954636543142
InteractionRGPD4 interactions

RGPD4 RGPD2 RANBP2 RGPD3

2.78e-0722524int:RGPD4
InteractionRGPD2 interactions

RGPD4 RGPD2 RANBP2 RGPD3

6.62e-0727524int:RGPD2
InteractionRGPD3 interactions

RGPD4 RGPD2 RANBP2 RGPD3

6.47e-0647524int:RGPD3
InteractionRGPD1 interactions

RGPD4 RGPD2 RANBP2 RGPD3

7.66e-0649524int:RGPD1
InteractionRGPD8 interactions

RGPD4 RGPD2 RANBP2 RGPD3

3.97e-0574524int:RGPD8
Cytoband15q15.2

TTBK2 STARD9

1.61e-041654215q15.2
Cytoband2q12.3

RGPD4 RANBP2

1.83e-04175422q12.3
Cytoband1p33

CYP4Z2P CYP4Z1

7.88e-04355421p33
CytobandEnsembl 112 genes in cytogenetic band chr1p33

CYP4Z2P CYP4Z1

2.38e-0361542chr1p33
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD2 NSD2 MECOM

5.72e-0534403487
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RGPD2 RANBP2 RGPD3

1.19e-04115404769
GeneFamilyAldo-keto reductases

KCNAB2 AKR1B15

4.92e-0415402399
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RANBP2 RBM10

9.76e-042140289
GeneFamilyPWWP domain containing

NSD2 DNMT3B

1.07e-03224021147
GeneFamilyCytochrome P450 family 4

CYP4Z2P CYP4Z1

2.87e-03364021003
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

DNAJB1 DNAJB5

5.26e-0349402584
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RGPD2 RANBP2 RGPD3

6.30e-0733544MM477
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RGPD2 RANBP2 RGPD3

1.87e-0643544MM3857
CoexpressionGSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP

MRC1 DNAJB1 AGO2 PLOD3 GNA15 DNAJB5

3.39e-06199546M7656
CoexpressionGSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_DN

ABCC4 TRNT1 KCNAB2 DNAJB5 GSN

5.74e-05200545M8958
CoexpressionGSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN

MRC1 AGO2 PLOD3 GNA15 DNAJB5

5.74e-05200545M7653
CoexpressionGSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN

NSD2 STARD9 MECOM NOSTRIN GSN

5.74e-05200545M7162
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 KCNAB2 MAP3K10 GNA15 METTL22

2.76e-0618254557f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

CYP4Z1 STARD9 MECOM GSN SMAD3

3.49e-0619154570c067c54084bfb02c29bab085f4defd477194fb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ABCA1 GAS2L3 ME1 GSN

3.77e-0619454545708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ABCA1 GAS2L3 ME1 GSN

3.87e-06195545247803cf58c6d9c561a52aa34e581188ddad197e
ToppCellBronchus_Control_(B.)-Immune-TX-MoAM-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

MRC1 DNAJB1 ABCA1 STXBP2 GAS2L3

4.17e-061985451d92b09aeb03a95fa9e221813002045c4f41dd24
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MRC1 ABCA1 GAS2L3 ME1 GSN

4.27e-06199545b827dd8a249f904a0ff930a6c4d3b00fb7bc6fb1
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MRC1 ABCA1 GAS2L3 ME1 GSN

4.27e-06199545c0dcdda30485bb920d3706dcfb06f11b76b6ea37
ToppCellmLN-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

MRC1 PLOD3 STXBP2 ADSS2 KCNAB2

4.37e-06200545e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 SEPTIN9 MFSD6 GSN

3.38e-051515443105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MRC1 ZNF469 GSN DNMT3B

4.14e-051595446115cb03c2ad08e4c1b65893d522f685ff0bc692
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MRC1 ZNF469 GSN DNMT3B

4.24e-05160544a90eb621481fd07a821495db07d1032e109fd386
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MRC1 STXBP2 KCNAB2 GNA15

4.89e-05166544ce570b768988e30898cf0387c2aa99989631f13f
ToppCellfacs-Heart-LV-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 STXBP2 GAS2L3 KCNAB2

5.37e-051705444eaa22040e475100061475123aefa32b56481464
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 STXBP2 GAS2L3 KCNAB2

5.37e-0517054460041b2e57e958f300a5bc76851705c8baf297c2
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 STXBP2 GAS2L3 KCNAB2

5.37e-05170544793dde64f5517538b66de5f461a445c4ad6dd7b3
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHAF1B ARID3A NSD2 GNA15

5.88e-0517454409b091e24317c3f7bac043f04762a533e30793de
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

MRC1 STXBP2 GAS2L3 KCNAB2

6.01e-05175544d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ARID3A RGPD3 ME1

6.42e-0517854424e8c62060455159235985f456af0c5023a7f3f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ARID3A RGPD3 ME1

6.42e-051785444f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1B STARD9 NOSTRIN GSN

6.42e-05178544375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCell10x5'-GI_large-bowel-Myeloid_Dendritic|GI_large-bowel / Manually curated celltypes from each tissue

MRC1 GAS2L3 GNA15 GSN

6.70e-05180544400f48aa2851d89bf3b60d721bc0f635f3ad86eb
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 GAS2L3 NSD2 ME1

6.70e-0518054443fd5c498a87bb078d101298b472656f3294686a
ToppCell10x5'-GI_large-bowel-Myeloid_Dendritic-DC2|GI_large-bowel / Manually curated celltypes from each tissue

MRC1 GAS2L3 GNA15 GSN

6.70e-05180544d4ebe67a2735e244c08b238320bbb441ca88ee6f
ToppCellfacs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGO2 AMOTL1 AIFM3 RAB39B

7.15e-05183544b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MRC1 ABCA1 TRIM50 ME1

7.45e-051855448207f9eff113eed429e961748c6b17d672a13b33
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN9 MECOM GSN SMAD3

7.77e-0518754477886f99c229610abd28c4c370d2c7d1536c9782
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 ABCA1 GNA15 TRIM50

7.93e-05188544cb091912f9b627a78a8793a37df7f1de839f887f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ABCA1 GAS2L3 ME1

8.43e-0519154451f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ABCA1 GAS2L3 ME1

8.43e-051915448fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

CYP4Z1 MECOM GSN SMAD3

8.60e-05192544356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D175|Adult / Lineage, Cell type, age group and donor

MRC1 ABCA1 GAS2L3 SEPTIN9

8.60e-05192544733491e932350e3c216a626cc49c3cd3fe970a82
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

MRC1 ABCA1 GAS2L3 ME1

8.78e-05193544a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellControl-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

MRC1 ABCA1 ARID3A GNA15

8.95e-05194544c35bf04d5e7450cb6679a036fcabb1b28f409f29
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ABCA1 GNA15 ME1

8.95e-051945441dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 CHAF1B GAS2L3 NSD2

9.13e-05195544c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

MRC1 ABCA1 ME1 GSN

9.13e-0519554410fa47bdcf6c9784ea930b75a5861e139421feed
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ABCA1 GAS2L3 ME1

9.13e-0519554442bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

CYP4Z1 MECOM GSN SMAD3

9.13e-05195544ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MRC1 ABCA1 STXBP2 KCNAB2

9.13e-051955440ec1b572bbb92b6da3440139366a4c1743b1ad92
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 ABCA1 GNA15 TRIM50

9.13e-05195544028622b234551b185977fbee10c06851a45456a5
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

MRC1 ABCA1 GAS2L3 KCNAB2

9.13e-0519554455e25f702af19146a161861cfd15f40bbda1dc35
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 ABCA1 GNA15 ME1

9.13e-0519554434a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ABCC4 MFSD6 NOSTRIN GSN

9.50e-0519754466339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCellHealthy_donor-cDC|Healthy_donor / disease group, cell group and cell class (v2)

MRC1 ZNF469 GNA15 GSN

9.50e-05197544b57a27e5b855bbdd1dfa352540599d260dc482aa
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DNAJB1 RANBP2 ABCC4 GSN

9.50e-05197544b597c292fc1cb381a4325fed15a32966c38def28
ToppCellHealthy/Control-cDC|Healthy/Control / Disease group and Cell class

MRC1 ZNF469 GNA15 GSN

9.50e-05197544926423aae9fcf654f84b0f7621103a6a22d3aced
ToppCellmild_COVID-19-cDC|mild_COVID-19 / disease group, cell group and cell class (v2)

MRC1 ZNF469 GNA15 GSN

9.50e-0519754444ebd3f967779bb7753fc6dcd9fde6d682f9ccd6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 ABCA1 ME1 GSN

9.69e-05198544579a22199643440b98e381147779ced630d4ed66
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 ABCA1 GAS2L3 ME1

9.69e-05198544c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 ABCA1 GAS2L3 KCNAB2

9.69e-051985446a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 ABCA1 GAS2L3 KCNAB2

9.69e-051985440b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 ABCA1 ME1 GSN

9.88e-05199544c4fc638a8dad3a9b77634e8912a9326c8a2f11f5
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 ABCA1 GAS2L3 TRIM50

9.88e-051995449545ac59c8d75f5747dff86cb511a149dc103b31
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 ABCA1 ME1 GSN

9.88e-05199544697a9a58c0cdb77222700d029873355d37f6ab28
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 GAS2L3 KCNAB2 GNA15

1.01e-042005446e50272d172b491200d9a255ed08e6d6998cfe02
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 GAS2L3 KCNAB2 GNA15

1.01e-04200544840be665639a53ba9bafc19f7a81ca1e0436e329
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AIFM3 MECOM TRIM50

5.86e-0413554388f86bab637f1ca1439c7de2d12be4329cf662b8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AIFM3 MECOM TRIM50

6.51e-041405435e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCellprimary_visual_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC25A3 STXBP2 SMAD3

6.65e-04141543605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RGPD4 AGO2 AHSA2P

6.93e-04143543bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADSS2 SEPTIN9 MECOM

7.65e-041485439fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ABCC4 MECOM NOSTRIN

7.80e-04149543d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCell(00)_Basal|World / shred by cell type and Timepoint

ABCA1 AMOTL1 GSN

7.80e-0414954349e39206f37cee124ca4763c79425b805e50624b
ToppCellE16.5-samps-Myeloid-Fetal_macrophage-macrophage_-_intermediate_-_unactivated|E16.5-samps / Age Group, Lineage, Cell class and subclass

MRC1 KCNAB2 GNA15

7.95e-0415054360fdd266aaca1b589b9a77465a4a7fad4921339a
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MRC1 ZNF469 DNMT3B

8.11e-04151543a937e3e5a63bfeb37d2cabb3177760ec583dbf11
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MRC1 ZNF469 DNMT3B

8.11e-04151543cba0939a6dd3519f6890695f5b237266ca1a7941
ToppCellSevere-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZNF469 RGPD3 AIFM3

8.42e-0415354344572f87d403e314050ab935d2cd676c33d9c287
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RGPD2 RGPD3 PDX1

8.42e-041535437480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

MRC1 STXBP2 GSN

8.74e-0415554303fd443740272dcb547e39deaf7ae89b8307f241
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK|Thalamus / BrainAtlas - Mouse McCarroll V32

ABCC4 MECOM NOSTRIN

8.74e-04155543fe6c4aba0e98cda84bf178aeac2e9fa834477f22
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RGPD2 RGPD3 PDX1

8.91e-0415654353ded973358e3e48054130131e959f0d1f4ef60f
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXW10 STXBP2 DNMT3B

8.91e-041565435b56217336771baf57d791efcb4e206c6aea83b1
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 MECOM TRIM50

8.91e-041565434d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZNF469 RGPD3 AIFM3

9.07e-04157543a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4Z1 MECOM TRIM50

9.58e-041605436005948e400e781cdb876ba350b3ec8991e3945f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

AMOTL1 AIFM3 GNA15

9.58e-04160543529034a1101d7772d82f86beb5c6fa9c9dd97067
ToppCellsevere_influenza-cDC|World / disease group, cell group and cell class (v2)

AMOTL1 MECOM DNMT3B

9.76e-04161543802f8cafb5f499e3b2ec0193d6eb1ac9320b9287
ToppCellE18.5-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|E18.5-samps / Age Group, Lineage, Cell class and subclass

MRC1 KCNAB2 GNA15

9.93e-0416254360d3fe1f5cec4285b8774ff078ebcc6bfaec26ed
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN9 MECOM RAB39B

9.93e-04162543285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCellE18.5-samps-Myeloid|E18.5-samps / Age Group, Lineage, Cell class and subclass

MRC1 KCNAB2 GNA15

9.93e-0416254318e4a807e25f754a69e9eaaddfde40f8de9b8512
ToppCellE18.5-samps-Myeloid-Macrophage|E18.5-samps / Age Group, Lineage, Cell class and subclass

MRC1 KCNAB2 GNA15

9.93e-041625430970e4eda60e3f015335e2726e6d565fb2f43372
ToppCellInfluenza_Severe-cDC|World / Disease group and Cell class

MECOM GNA15 DNMT3B

1.03e-03164543c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCellfacs-BAT-Fat-18m-Lymphocytic-NK_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN9 KCNAB2 GNA15

1.03e-03164543ab9c17f86b98e1a4d5db1bd3086edab1320ebda8
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHAF1B NSD2 GNA15

1.03e-031645435621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 ABCA1 GNA15

1.05e-031655438d3d5860a4785c4908160ae5fcb421ee80bd78ce
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 ABCA1 GNA15

1.05e-0316554317ee6f269ed8d378465cf00ca59d48d8b106808e
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic|TCGA-Mesothelium / Sample_Type by Project: Shred V9

CHAF1B ZNF469 RBM10

1.08e-031675439062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

MRC1 ABCA1 GSN

1.10e-031685438ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCelldroplet-Heart-4Chambers-21m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 STXBP2 KCNAB2

1.10e-031685438ff4666fdda562913060b1cfa2dfab34e0606794
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 STXBP2 KCNAB2

1.12e-031695433296305dc4fa40c466dab56aab4eac302ae3d7f7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

ABCC4 MECOM TRIM50

1.14e-03170543269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

MRC1 GAS2L3 ME1

1.14e-031705434232fe937909f93d3736988c707b8f95ce993398
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 STXBP2 KCNAB2

1.14e-031705438ea5ab8c890eb91c5b0aae3996e1d1c61c97f0c7
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l12-45|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 ABCA1 GAS2L3

1.14e-03170543e028e22ad051c2628248b212b5d28b891e0ee782
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRNT1 GNA15 DNMT3B

1.18e-0317254337ff83f53e99df62691d078ca6801b2c0ec2b123
ToppCellMS-CD8-proli_CD4|MS / Condition, Cell_class and T cell subcluster

RGPD2 ABCC4 RBM10

1.18e-031725430b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCellControl-MAIT|Control / Disease group and Cell class

CHAF1B ABCA1 ME1

1.18e-03172543552bc62e8e8bb0ac1cd0452f4410a3af087787eb
ToppCellmetastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

GNA15 UNC80 GSN

1.18e-0317254338d17e769fe8eac8b57b820490d4ddd969243ee7
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

MRC1 STXBP2 UNC80

1.20e-031735434efa0878ed1ede8fa5d6c191a76d4f70558ba761
ToppCellfacs-Heart-LA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 ABCA1 GNA15

1.22e-0317454330c083fe4711735e83dccfd00fcd746ae673d353
Diseaseautosomal dominant limb-girdle muscular dystrophy type 1 (implicated_via_orthology)

DNAJB1 DNAJB5

1.62e-054492DOID:0110305 (implicated_via_orthology)
Diseasecongenital myopathy 21 (implicated_via_orthology)

DNAJB1 DNAJB5

1.62e-054492DOID:0081353 (implicated_via_orthology)
Disease10-undecenoate 11:1n1 measurement

CYP4Z2P CYP4Z1

5.64e-057492EFO_0021099
Diseaselung adenocarcinoma (is_implicated_in)

SETD2 RBM10 DNMT3B

7.51e-0549493DOID:3910 (is_implicated_in)
DiseaseBMI-adjusted waist-hip ratio, asthma

MECOM SMAD3

1.21e-0410492EFO_0007788, MONDO_0004979
Diseasealpha-hydroxybutyric acid measurement

ABCC4 NOSTRIN

1.76e-0412492EFO_0010458
Diseasekeratoconus

ZNF469 AIFM3 SMAD3

1.83e-0466493MONDO_0015486
Diseaseintraocular pressure measurement

ZNF469 ABCA1 ADSS2 SEPTIN9 MECOM SMAD3

1.91e-04509496EFO_0004695
Diseaseskin melanoma (is_marker_for)

CHAF1B DNMT3B

2.08e-0413492DOID:8923 (is_marker_for)
Diseaseextrahepatic cholestasis (biomarker_via_orthology)

ABCC4 ABCA1

3.62e-0417492DOID:13619 (biomarker_via_orthology)
DiseaseMyeloid Leukemia

AGO2 MECOM

4.06e-0418492C0023470
DiseaseLeukemia, Monocytic, Chronic

AGO2 MECOM

4.06e-0418492C0023466
Diseasegastric ulcer

PDX1 MECOM

5.56e-0421492EFO_0009454
DiseaseAntiglaucoma preparations and miotics use measurement

ABCA1 MECOM

8.56e-0426492EFO_0009944
Diseasespine bone mineral density

CHAF1B MECOM SMAD3

1.03e-03119493EFO_0007701
Diseasecolorectal cancer (is_implicated_in)

SETD2 RBM10 SEPTIN9

1.08e-03121493DOID:9256 (is_implicated_in)
Diseasebasophil count

SETD2 ZNF469 TRNT1 ARFRP1 NOSTRIN

1.21e-03483495EFO_0005090
Diseasepeptic ulcer disease

PDX1 MECOM

1.38e-0333492MONDO_0004247
Diseasehepatocellular carcinoma (is_marker_for)

ABCA1 PLOD3 RBM10 DNMT3B

1.57e-03301494DOID:684 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
KLGWKGIVKESGVKH

AHSA2P

86

Q719I0
VGRGLVTLDGSKWKK

CYP4Z2P

121

Q8N1L4
LHIVIKRGWKEGTKI

DNAJB5

211

O75953
KVLELEGEKGEWGFK

COPS2

56

P61201
GGTIWKIVKDGEEEI

CPSF2

156

Q9P2I0
KEFGIGDLVWGKIKG

DNMT3B

221

Q9UBC3
VELGWGKVLLVKDNG

AIFM3

86

Q96NN9
GKVSKAAWIRKIKGL

FBXW10

1016

Q5XX13
VGKVGEWAIRKLGLV

ABCA1

2021

O95477
VRIWKVEKGPDGKAI

CHAF1B

41

Q13112
EEKTWKGSIGLLLGK

AMOTL1

821

Q8IY63
RGIAGEKFDIVKKWG

ARFIP2

86

P53365
DKILTIEVKKGWKEG

DNAJB1

201

P25685
GEGKDRIFKVSIKWV

AGO2

121

Q9UKV8
VGQWKERGIGDIKIL

RANBP2

2346

P49792
WKEGSGLGRKKQGIV

RBM10

871

P98175
KRGEITIQEGWEGVK

RAB39B

176

Q96DA2
GLGIWTKRKIEVGEK

MECOM

91

Q03112
ARTVGGGQKVRWLKK

PLOD3

81

O60568
LVLKRLGFKGVWKGL

SLC25A3

301

Q00325
KEELVGGKKKGRTWG

MAP3K10

546

Q02779
IWLVDSKGLIVKGRA

ME1

331

P48163
GKGLEWVGRIKSKTD

IGHV3-15

61

A0A0B4J1V0
WKKEEDKKRGGGTAV

PDX1

201

P52945
KIIKTDGKGWGLVAK

NSD2

1066

O96028
IVDVGGQKSERKKWI

GNA15

206

P30679
WGVVADRFKKGKIVL

MFSD6

121

Q6ZSS7
EVVLGNIIKKKGWRR

KCNAB2

96

Q13303
GKIWIDKILTTEIGL

ABCC4

1096

O15439
VGQWKERGIGDIKIL

RGPD3

1371

A6NKT7
LTGKGVREGIEWMVK

ARFRP1

171

Q13795
IWLSGLLGIKVKAEK

GAS2L3

56

Q86XJ1
KAGKEPGLQIWRVEK

GSN

61

P06396
CRVVKGKLVEVGKWP

PRSS46P

41

E5RG02
KGDIVIIHEKKEGGW

NOSTRIN

461

Q8IVI9
EIVEVEKGCRKGWKK

MRC1

496

P22897
VGQWKERGIGDIKIL

RGPD4

1371

Q7Z3J3
AGISGERIWVELKKI

TRNT1

231

Q96Q11
KDVGQWKERGIGDIK

RGPD2

1361

P0DJD1
KRILGRKTKWGTIEV

SEPTIN9

511

Q9UHD8
KGKGLEGWEKRLIIS

ADSS2

116

P30520
KWEGKNETGLLEKGL

STARD9

1971

Q9P2P6
TGGGIVRVKELDWLK

METTL22

256

Q9BUU2
VGLGTWRSLLGKVKE

AKR1B15

16

C9JRZ8
EKGGLVEVINKKLWR

ARID3A

281

Q99856
VGRGLVTLDGSKWKK

CYP4Z1

121

Q86W10
GIEKGGWQTTILGKL

UNC80

506

Q8N2C7
VDVGDKVWVKLIGRE

ZCCHC17

61

Q9NP64
IVKRLLGWKKGEQNG

SMAD3

11

P84022
SGVIRSVKKDGEWKV

STXBP2

16

Q15833
LVKERWKVLRKIGGG

TTBK2

16

Q6IQ55
DVEVILTEKKGWGLR

SETD2

1551

Q9BYW2
ARGGAWGKELILKIV

ZNF469

1041

Q96JG9
WRLGVIKGTASRKGK

TRIM50

361

Q86XT4