Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	chromatin binding	LDB1 TLE1 FOSL2 ASH1L GATA2 AUTS2 PAX3 TBR1 ARID1A TCF7L1 SVEP1 STPG4	6.14e-07	739	55	12	GO:0003682
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	PAX8 NEUROD4 FOSL2 GATA2 ETV3 E2F7 DMRTA1 KLF17 PAX3 TBR1 MYRF TCF7L1 MEIS2	9.21e-05	1412	55	13	GO:0000981
GeneOntologyMolecularFunction	transcription coregulator activity	LDB1 ATN1 PPRC1 TLE1 RAD54L2 SSBP3 ARID1A SF1	1.42e-04	562	55	8	GO:0003712
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CECR2 RAD54L2 ARID1A	1.44e-04	37	55	3	GO:0140658
GeneOntologyMolecularFunction	disaccharide binding	LGALS9C LGALS9B	1.55e-04	7	55	2	GO:0048030
GeneOntologyMolecularFunction	galactoside binding	LGALS9C LGALS9B	2.65e-04	9	55	2	GO:0016936
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	PAX8 NEUROD4 FOSL2 GATA2 E2F7 DMRTA1 KLF17 PAX3 TBR1 TCF7L1 MEIS2	4.96e-04	1244	55	11	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	PAX8 NEUROD4 FOSL2 GATA2 ETV3 E2F7 DMRTA1 KLF17 PAX3 TBR1 TCF7L1 MEIS2	5.10e-04	1459	55	12	GO:0000977
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	PAX8 NEUROD4 FOSL2 GATA2 E2F7 DMRTA1 KLF17 PAX3 TBR1 TCF7L1 MEIS2	5.94e-04	1271	55	11	GO:0000987
GeneOntologyMolecularFunction	oligosaccharide binding	LGALS9C LGALS9B	1.37e-03	20	55	2	GO:0070492
GeneOntologyMolecularFunction	transcription coactivator activity	LDB1 ATN1 PPRC1 SSBP3 ARID1A	1.46e-03	303	55	5	GO:0003713
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	LDB1 PAX8 PPRC1 NEUROD4 FOSL2 ASH1L GATA2 E2F7 AUTS2 PAX3 RAD54L2 TBR1 SSBP3 TCF7L1 MEIS2	2.28e-06	1390	55	15	GO:0045944
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	LDB1 ATN1 TLE1 GATA2 ETV3 E2F7 KLF17 PAX3 TBR1 ARID1A TCF7L1 SF1 MEIS2 HNRNPL ZNF503	2.47e-06	1399	55	15	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	LDB1 ATN1 TLE1 GATA2 ETV3 E2F7 KLF17 PAX3 TBR1 ARID1A TCF7L1 SF1 MEIS2 HNRNPL ZNF503	2.79e-06	1413	55	15	GO:1902679
GeneOntologyBiologicalProcess	stem cell population maintenance	FZD7 LDB1 PAX8 GATA2 ARID1A TCF7L1	3.91e-05	237	55	6	GO:0019827
GeneOntologyBiologicalProcess	negative regulation of natural killer cell degranulation	LGALS9C LGALS9B	4.17e-05	4	55	2	GO:0043322
GeneOntologyBiologicalProcess	maintenance of cell number	FZD7 LDB1 PAX8 GATA2 ARID1A TCF7L1	4.39e-05	242	55	6	GO:0098727
GeneOntologyBiologicalProcess	commitment of neuronal cell to specific neuron type in forebrain	GATA2 TBR1	1.04e-04	6	55	2	GO:0021902
GeneOntologyBiologicalProcess	specification of animal organ identity	PAX8 PAX3 TBR1	1.78e-04	41	55	3	GO:0010092
GeneOntologyBiologicalProcess	primitive erythrocyte differentiation	LDB1 GATA2	1.93e-04	8	55	2	GO:0060319
GeneOntologyBiologicalProcess	regulation of natural killer cell degranulation	LGALS9C LGALS9B	1.93e-04	8	55	2	GO:0043321
GeneOntologyBiologicalProcess	somatic stem cell population maintenance	LDB1 PAX8 GATA2 TCF7L1	1.97e-04	108	55	4	GO:0035019
GeneOntologyBiologicalProcess	forebrain neuron fate commitment	GATA2 TBR1	2.48e-04	9	55	2	GO:0021877
GeneOntologyBiologicalProcess	embryo development	FZD7 LDB1 PAX8 CECR2 KIAA1217 GATA2 E2F7 PAX3 SSBP3 ARID1A TCF7L1 MEIS2	3.31e-04	1437	55	12	GO:0009790
GeneOntologyCellularComponent	transcription regulator complex	LDB1 PAX8 TLE1 FOSL2 GATA2 ETV3 E2F7 PAX3 SSBP3 TCF7L1	3.03e-06	596	55	10	GO:0005667
GeneOntologyCellularComponent	chromatin	LDB1 PAX8 NEUROD4 CECR2 FOSL2 ETV3 E2F7 DMRTA1 KLF17 PAX3 TBR1 ARID1A TCF7L1 MEIS2 HNRNPL	4.19e-06	1480	55	15	GO:0000785
GeneOntologyCellularComponent	beta-catenin-TCF complex	LDB1 TLE1 TCF7L1	4.84e-06	13	55	3	GO:1990907
GeneOntologyCellularComponent	RNA polymerase II transcription regulator complex	LDB1 TLE1 FOSL2 E2F7 TCF7L1	7.35e-04	272	55	5	GO:0090575
MousePheno	increased somite number	LDB1 TCF7L1	3.46e-05	3	48	2	MP:0012181
Domain	PAX	PAX8 PAX3	3.02e-04	9	55	2	SM00351
Domain	Paired_dom	PAX8 PAX3	3.02e-04	9	55	2	IPR001523
Domain	PAIRED_2	PAX8 PAX3	3.02e-04	9	55	2	PS51057
Domain	PAX	PAX8 PAX3	3.02e-04	9	55	2	PF00292
Domain	PAIRED_1	PAX8 PAX3	3.02e-04	9	55	2	PS00034
Domain	Gal-bind_lectin	LGALS9C LGALS9B	8.72e-04	15	55	2	PF00337
Domain	Gal-bind_lectin	LGALS9C LGALS9B	8.72e-04	15	55	2	SM00908
Domain	GALECTIN	LGALS9C LGALS9B	8.72e-04	15	55	2	PS51304
Domain	Galectin_CRD	LGALS9C LGALS9B	8.72e-04	15	55	2	IPR001079
Domain	GLECT	LGALS9C LGALS9B	8.72e-04	15	55	2	SM00276
Domain	-	LGALS9C LGALS9B SVEP1	2.76e-03	95	55	3	2.60.120.200
Domain	-	PAX8 ETV3 E2F7 PAX3	3.87e-03	218	55	4	1.10.10.10
Domain	BROMODOMAIN_1	CECR2 ASH1L	5.31e-03	37	55	2	PS00633
Domain	WHTH_DNA-bd_dom	PAX8 ETV3 E2F7 PAX3	5.59e-03	242	55	4	IPR011991
Domain	Bromodomain	CECR2 ASH1L	5.59e-03	38	55	2	PF00439
Domain	KH_1	ANKHD1 SF1	5.59e-03	38	55	2	PF00013
Domain	KH	ANKHD1 SF1	6.18e-03	40	55	2	SM00322
Domain	KH_dom	ANKHD1 SF1	6.18e-03	40	55	2	IPR004087
Domain	-	HELZ MBNL3	6.18e-03	40	55	2	4.10.1000.10
Domain	BROMODOMAIN_2	CECR2 ASH1L	6.49e-03	41	55	2	PS50014
Domain	KH_TYPE_1	ANKHD1 SF1	6.80e-03	42	55	2	PS50084
Domain	BROMO	CECR2 ASH1L	6.80e-03	42	55	2	SM00297
Domain	Bromodomain	CECR2 ASH1L	6.80e-03	42	55	2	IPR001487
Domain	-	CECR2 ASH1L	6.80e-03	42	55	2	1.20.920.10
Domain	KH_dom_type_1	ANKHD1 SF1	7.44e-03	44	55	2	IPR004088
Domain	ZnF_C3H1	HELZ MBNL3	8.81e-03	48	55	2	SM00356
Pubmed	A census of human transcription factors: function, expression and evolution.	PAX8 NEUROD4 FOSL2 ASH1L GATA2 ETV3 E2F7 DMRTA1 PAX3 TBR1 MYRF TCF7L1 MEIS2 MBNL3	9.98e-11	908	55	14	19274049
Pubmed	Human transcription factor protein interaction networks.	LDB1 ATN1 PAX8 TLE1 GATA2 ETV3 AUTS2 HELZ RAD54L2 TBR1 SSBP3 ARID1A ANKHD1 MRPL24 HNRNPL ZNF503	3.97e-10	1429	55	16	35140242
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	LDB1 NEUROD4 FOSL2 GATA2 KLF17 PAX3 ARID1A MRPL24 TCF7L1 SF1 MEIS2	1.24e-08	709	55	11	22988430
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	LDB1 FOSL2 ASH1L GATA2 ETV3 KLF17 ARID1A TCF7L1 SF1 MEIS2 MBNL3	4.69e-08	808	55	11	20412781
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	LDB1 ATN1 AUTS2 SSBP3 SF1 ZNF503	1.53e-07	152	55	6	38360978
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	PAX8 GATA2 ETV3 E2F7 DMRTA1 KLF17 PAX3 TCF7L1 MEIS2	1.76e-07	544	55	9	28473536
Pubmed	Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.	E2F7 SSBP3 ANKHD1 TCF7L1 MEIS2	3.44e-07	91	55	5	21194568
Pubmed	LMO4 functions as a co-activator of neurogenin 2 in the developing cortex.	LDB1 NEUROD4 TBR1	4.46e-07	10	55	3	21652654
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	ATN1 TLE1 AUTS2 HELZ FNDC3A ARID1A ANKHD1 ZNF503	5.93e-07	457	55	8	32344865
Pubmed	LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons.	LDB1 GATA2 SSBP3	8.15e-07	12	55	3	19323994
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FZD7 PPRC1 SHISA5 FOSL2 GATA2 ATG2A ARID1A ANKHD1 MYRF ABCA7 ZNF503	1.05e-06	1105	55	11	35748872
Pubmed	Interaction network of human early embryonic transcription factors.	LDB1 ATN1 TLE1 AUTS2 RAD54L2 ARID1A ZNF503	1.34e-06	351	55	7	38297188
Pubmed	Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition.	NEUROD4 TBR1 MEIS2 ZNF503	1.93e-06	56	55	4	34170322
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	LDB1 ATN1 TLE1 FOSL2 ETV3 ARID1A	4.18e-06	268	55	6	33640491
Pubmed	T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration.	FZD7 NEUROD4 GATA2	4.88e-06	21	55	3	17119020
Pubmed	The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer.	PAX8 GATA2 PAX3 MEIS2	6.26e-06	75	55	4	37298722
Pubmed	Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.	LGALS9C LGALS9B	7.36e-06	3	55	2	29458010
Pubmed	Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.	LGALS9C LGALS9B	7.36e-06	3	55	2	19776007
Pubmed	Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.	LGALS9C LGALS9B	7.36e-06	3	55	2	26582205
Pubmed	Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.	LGALS9C LGALS9B	7.36e-06	3	55	2	9153289
Pubmed	Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.	LGALS9C LGALS9B	7.36e-06	3	55	2	33316546
Pubmed	Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.	LGALS9C LGALS9B	7.36e-06	3	55	2	18974023
Pubmed	Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.	LGALS9C LGALS9B	7.36e-06	3	55	2	9038233
Pubmed	Single-stranded DNA-binding proteins regulate the abundance and function of the LIM-homeodomain transcription factor LHX2 in pituitary cells.	LDB1 SSBP3	7.36e-06	3	55	2	18565323
Pubmed	Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.	LGALS9C LGALS9B	7.36e-06	3	55	2	23144904
Pubmed	Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.	LGALS9C LGALS9B	7.36e-06	3	55	2	29651447
Pubmed	Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.	LGALS9C LGALS9B	7.36e-06	3	55	2	28704475
Pubmed	The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.	LGALS9C LGALS9B	7.36e-06	3	55	2	21146220
Pubmed	Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.	LGALS9C LGALS9B	7.36e-06	3	55	2	23836896
Pubmed	Modifier locus for exencephaly in Cecr2 mutant mice is syntenic to the 10q25.3 region associated with neural tube defects in humans.	CECR2 PAX3	7.36e-06	3	55	2	17623803
Pubmed	Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.	LGALS9C LGALS9B	7.36e-06	3	55	2	7890611
Pubmed	Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.	LGALS9C LGALS9B	7.36e-06	3	55	2	22341088
Pubmed	Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.	LGALS9C LGALS9B	7.36e-06	3	55	2	28990062
Pubmed	Galectin-9 Is a Novel Regulator of Epithelial Restitution.	LGALS9C LGALS9B	7.36e-06	3	55	2	32380082
Pubmed	Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.	LGALS9C LGALS9B	7.36e-06	3	55	2	23667648
Pubmed	Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.	LGALS9C LGALS9B	7.36e-06	3	55	2	18579572
Pubmed	Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.	LGALS9C LGALS9B	7.36e-06	3	55	2	28877989
Pubmed	Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.	LGALS9C LGALS9B	7.36e-06	3	55	2	19800850
Pubmed	The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.	LGALS9C LGALS9B	7.36e-06	3	55	2	38987795
Pubmed	Ssdp proteins bind to LIM-interacting co-factors and regulate the activity of LIM-homeodomain protein complexes in vivo.	LDB1 SSBP3	7.36e-06	3	55	2	12642495
Pubmed	Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.	LGALS9C LGALS9B	7.36e-06	3	55	2	16990264
Pubmed	Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.	LGALS9C LGALS9B	7.36e-06	3	55	2	18005988
Pubmed	Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.	LGALS9C LGALS9B	7.36e-06	3	55	2	23585851
Pubmed	Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.	LGALS9C LGALS9B	7.36e-06	3	55	2	24477688
Pubmed	A unique role for galectin-9 in angiogenesis and inflammatory arthritis.	LGALS9C LGALS9B	7.36e-06	3	55	2	29433546
Pubmed	Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.	LGALS9C LGALS9B	7.36e-06	3	55	2	37105392
Pubmed	Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.	LGALS9C LGALS9B	7.36e-06	3	55	2	36479526
Pubmed	Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.	LGALS9C LGALS9B	7.36e-06	3	55	2	23242525
Pubmed	Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.	LGALS9C LGALS9B	7.36e-06	3	55	2	19851072
Pubmed	The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.	LGALS9C LGALS9B	7.36e-06	3	55	2	33923930
Pubmed	Alarmin function of galectin-9 in murine respiratory tularemia.	LGALS9C LGALS9B	7.36e-06	3	55	2	25898318
Pubmed	Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.	LGALS9C LGALS9B	7.36e-06	3	55	2	31937306
Pubmed	Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.	LGALS9C LGALS9B	7.36e-06	3	55	2	21426359
Pubmed	Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.	LGALS9C LGALS9B	7.36e-06	3	55	2	31969388
Pubmed	Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.	LGALS9C LGALS9B	7.36e-06	3	55	2	18282810
Pubmed	Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.	LGALS9C LGALS9B	7.36e-06	3	55	2	35241678
Pubmed	Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.	LGALS9C LGALS9B	7.36e-06	3	55	2	24083426
Pubmed	Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.	LGALS9C LGALS9B	7.36e-06	3	55	2	37279535
Pubmed	The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.	LGALS9C LGALS9B	7.36e-06	3	55	2	25931247
Pubmed	Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.	LGALS9C LGALS9B	7.36e-06	3	55	2	22627368
Pubmed	Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.	LGALS9C LGALS9B	7.36e-06	3	55	2	33153471
Pubmed	T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.	LGALS9C LGALS9B	7.36e-06	3	55	2	22052881
Pubmed	Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.	LGALS9C LGALS9B	7.36e-06	3	55	2	17560833
Pubmed	Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.	LGALS9C LGALS9B	7.36e-06	3	55	2	35643073
Pubmed	Galectin-9 functionally impairs natural killer cells in humans and mice.	LGALS9C LGALS9B	7.36e-06	3	55	2	23408620
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	LDB1 PAX8 NEUROD4 TLE1 ASH1L GATA2 PAX3 SSBP3 MEIS2	8.90e-06	877	55	9	20211142
Pubmed	SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.	LGALS9C LGALS9B	1.47e-05	4	55	2	38686388
Pubmed	Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.	LGALS9C LGALS9B	1.47e-05	4	55	2	22677125
Pubmed	Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.	LGALS9C LGALS9B	1.47e-05	4	55	2	19234217
Pubmed	Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.	LGALS9C LGALS9B	1.47e-05	4	55	2	35715604
Pubmed	Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.	LGALS9C LGALS9B	1.47e-05	4	55	2	19017954
Pubmed	Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification.	LDB1 PAX3	1.47e-05	4	55	2	31127120
Pubmed	Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.	LGALS9C LGALS9B	1.47e-05	4	55	2	33963043
Pubmed	Galectin-9: A novel promoter of atherosclerosis progression.	LGALS9C LGALS9B	1.47e-05	4	55	2	36459823
Pubmed	Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.	LGALS9C LGALS9B	1.47e-05	4	55	2	33107565
Pubmed	Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.	LGALS9C LGALS9B	1.47e-05	4	55	2	29611821
Pubmed	Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.	LGALS9C LGALS9B	1.47e-05	4	55	2	30763585
Pubmed	Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.	LGALS9C LGALS9B	1.47e-05	4	55	2	33727589
Pubmed	Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.	LGALS9C LGALS9B	1.47e-05	4	55	2	19362679
Pubmed	The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.	LGALS9C LGALS9B	1.47e-05	4	55	2	25578313
Pubmed	Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.	LGALS9C LGALS9B	1.47e-05	4	55	2	29844236
Pubmed	Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.	LGALS9C LGALS9B	1.47e-05	4	55	2	20463811
Pubmed	Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.	LGALS9C LGALS9B	1.47e-05	4	55	2	32855403
Pubmed	Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.	LGALS9C LGALS9B	1.47e-05	4	55	2	23657851
Pubmed	Fine genetic mapping of the proximal part of mouse chromosome 2 excludes Pax-8 as a candidate gene for Danforth's short tail (Sd).	PAX8 KIAA1217	1.47e-05	4	55	2	8318736
Pubmed	[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].	LGALS9C LGALS9B	1.47e-05	4	55	2	18826117
Pubmed	The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.	LGALS9C LGALS9B	1.47e-05	4	55	2	24333756
Pubmed	The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.	LGALS9C LGALS9B	1.47e-05	4	55	2	38853593
Pubmed	Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development.	LDB1 SSBP3	1.47e-05	4	55	2	12381786
Pubmed	Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.	LGALS9C LGALS9B	1.47e-05	4	55	2	24958847
Pubmed	Galectin-9 binds IgM-BCR to regulate B cell signaling.	LGALS9C LGALS9B	1.47e-05	4	55	2	30120235
Pubmed	[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].	LGALS9C LGALS9B	1.47e-05	4	55	2	21575348
Pubmed	Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.	LGALS9C LGALS9B	1.47e-05	4	55	2	18346632
Pubmed	Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.	LGALS9C LGALS9B	1.47e-05	4	55	2	11839756
Pubmed	Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.	LGALS9C LGALS9B	1.47e-05	4	55	2	19670381
Pubmed	Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.	LGALS9C LGALS9B	1.47e-05	4	55	2	25450716
Pubmed	The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.	LGALS9C LGALS9B	1.47e-05	4	55	2	16286920
Pubmed	Galectin-9 regulates the threshold of B cell activation and autoimmunity.	LGALS9C LGALS9B	1.47e-05	4	55	2	34369876
Pubmed	Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.	LGALS9C LGALS9B	1.47e-05	4	55	2	33203936
Pubmed	Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.	LGALS9C LGALS9B	1.47e-05	4	55	2	22021615
Interaction	TLE3 interactions	LDB1 ATN1 PAX8 TLE1 CECR2 GATA2 AUTS2 HELZ RAD54L2 TBR1 ARID1A SVEP1 HNRNPL ZNF503	1.06e-12	376	55	14	int:TLE3
Interaction	NFIB interactions	LDB1 PAX8 TLE1 GATA2 ETV3 TBR1 SSBP3 ARID1A HNRNPL	1.60e-10	142	55	9	int:NFIB
Interaction	EYA4 interactions	LDB1 ATN1 MAPK1IP1L GATA2 AUTS2 HELZ SSBP3 SF1 ZNF503	1.82e-08	243	55	9	int:EYA4
Interaction	TLX1 interactions	LDB1 ATN1 TLE1 AUTS2 SSBP3 ARID1A MEIS2 ZNF503	2.37e-08	175	55	8	int:TLX1
Interaction	NFIA interactions	PAX8 TLE1 GATA2 ETV3 TBR1 SSBP3 ARID1A HNRNPL	4.14e-08	188	55	8	int:NFIA
Interaction	ZNF608 interactions	ATN1 PAX8 GATA2 AUTS2 TBR1 HNRNPL	1.98e-07	93	55	6	int:ZNF608
Interaction	PRRC2B interactions	ATN1 PAX8 TLE1 CECR2 GATA2 HELZ ANKHD1 SF1	5.74e-07	265	55	8	int:PRRC2B
Interaction	TBR1 interactions	LDB1 TLE1 TBR1 SSBP3 ARID1A ZNF503	6.30e-07	113	55	6	int:TBR1
Interaction	LDB1 interactions	LDB1 PAX8 GATA2 TBR1 SSBP3 HNRNPL	6.99e-07	115	55	6	int:LDB1
Interaction	TBXT interactions	LDB1 ATN1 TLE1 TBR1 SSBP3 ARID1A	7.35e-07	116	55	6	int:TBXT
Interaction	SSBP3 interactions	LDB1 PAX8 GATA2 TBR1 SSBP3 HNRNPL	8.55e-07	119	55	6	int:SSBP3
Interaction	ZNF609 interactions	ATN1 PAX8 GATA2 AUTS2 TBR1 HNRNPL	2.82e-06	146	55	6	int:ZNF609
Interaction	CHD7 interactions	RHBDD1 PAX8 GATA2 ETV3 TBR1 ARID1A	3.30e-06	150	55	6	int:CHD7
Interaction	BCL9 interactions	LDB1 PAX8 GATA2 TBR1 SSBP3	3.70e-06	86	55	5	int:BCL9
Interaction	GSC interactions	LDB1 ATN1 TLE1 AUTS2 ZNF503	3.92e-06	87	55	5	int:GSC
Interaction	TLE4 interactions	PAX8 TLE1 GATA2 PAX3 TBR1	5.16e-06	92	55	5	int:TLE4
Interaction	DPF1 interactions	PAX8 GATA2 ETV3 TBR1 ARID1A	6.04e-06	95	55	5	int:DPF1
Interaction	SS18L1 interactions	ATN1 PAX8 MAPK1IP1L SSBP3 ARID1A	7.04e-06	98	55	5	int:SS18L1
Interaction	PAX8 interactions	LDB1 PAX8 TLE1 SSBP3 ARID1A	1.29e-05	111	55	5	int:PAX8
Interaction	LHX8 interactions	LDB1 TLE1 FOSL2 SSBP3	1.32e-05	53	55	4	int:LHX8
Interaction	GATA2 interactions	LDB1 TLE1 GATA2 SSBP3 ARID1A ZNF503	1.67e-05	199	55	6	int:GATA2
Interaction	ZNF503 interactions	ATN1 GATA2 TBR1 ZNF503	1.76e-05	57	55	4	int:ZNF503
Interaction	SP7 interactions	LDB1 ATN1 TLE1 TBR1 SSBP3 ARID1A ZNF503	1.81e-05	304	55	7	int:SP7
Interaction	NUP35 interactions	ATN1 TLE1 AUTS2 HELZ FNDC3A ARID1A ANKHD1 ZNF503	1.84e-05	424	55	8	int:NUP35
Interaction	FEV interactions	LDB1 TLE1 RAD54L2 SSBP3 ARID1A ZNF503	1.86e-05	203	55	6	int:FEV
Interaction	PAX7 interactions	LDB1 TLE1 SSBP3 ARID1A ZNF503	2.21e-05	124	55	5	int:PAX7
Interaction	NFIC interactions	PAX8 TLE1 GATA2 TBR1 ARID1A HNRNPL	2.26e-05	210	55	6	int:NFIC
Interaction	FBRSL1 interactions	PAX8 GATA2 TBR1 HNRNPL	2.31e-05	61	55	4	int:FBRSL1
Interaction	TLE5 interactions	ATN1 PAX8 TLE1 GATA2 TBR1 SPATA25 HNRNPL ZNF503	2.52e-05	443	55	8	int:TLE5
Interaction	PAX9 interactions	LDB1 ATN1 TLE1 ARID1A ZNF503	2.78e-05	130	55	5	int:PAX9
Interaction	KMT2C interactions	ATN1 PAX8 GATA2 TBR1 HNRNPL	3.21e-05	134	55	5	int:KMT2C
Interaction	RBPMS interactions	LGALS9C ATN1 GATA2 RAD54L2 ANKHD1 SF1 MEIS2	3.70e-05	340	55	7	int:RBPMS
Interaction	ATXN1L interactions	PAX8 GATA2 RAD54L2 TBR1 ANKHD1	5.51e-05	150	55	5	int:ATXN1L
Interaction	TAF1 interactions	LDB1 ATN1 PAX3 ABCA7 TCF7L1 SPATA25	7.43e-05	260	55	6	int:TAF1
Interaction	KRTAP6-3 interactions	MAPK1IP1L GATA2 AUTS2 RAD54L2 MEIS2	7.71e-05	161	55	5	int:KRTAP6-3
Interaction	KDM6A interactions	PAX8 TLE1 GATA2 TBR1 HNRNPL	7.93e-05	162	55	5	int:KDM6A
Interaction	NCOR2 interactions	PAX8 GATA2 HELZ TBR1 SF1 HNRNPL	8.08e-05	264	55	6	int:NCOR2
Interaction	IRF4 interactions	LDB1 TLE1 SSBP3 ARID1A	8.53e-05	85	55	4	int:IRF4
Interaction	ATXN1 interactions	GPD2 LDB1 PAX8 GATA2 PTPN23 RAD54L2 TBR1 ARID1A ANKHD1 SF1 HNRNPL	9.60e-05	1039	55	11	int:ATXN1
Interaction	EGR2 interactions	LDB1 ATN1 TLE1 RAD54L2 ARID1A	1.02e-04	171	55	5	int:EGR2
Interaction	ZSWIM4 interactions	SSBP3 HNRNPL	1.09e-04	6	55	2	int:ZSWIM4
Interaction	SOX10 interactions	LDB1 TLE1 PAX3 ARID1A	1.16e-04	92	55	4	int:SOX10
Interaction	LMX1B interactions	LDB1 SSBP3 MEIS2	1.18e-04	35	55	3	int:LMX1B
Interaction	ARID1B interactions	PAX8 GATA2 TBR1 ARID1A ZNF503	1.20e-04	177	55	5	int:ARID1B
Interaction	RBFOX2 interactions	ATN1 MAPK1IP1L HELZ ANKHD1 SF1 HNRNPL	1.21e-04	284	55	6	int:RBFOX2
Interaction	DNTTIP1 interactions	PAX8 GATA2 TBR1 HNRNPL	1.31e-04	95	55	4	int:DNTTIP1
Interaction	ALG13 interactions	ATN1 TLE1 HELZ ARID1A SF1	1.41e-04	183	55	5	int:ALG13
Interaction	SSPOP interactions	ATN1 HNRNPL	1.52e-04	7	55	2	int:SSPOP
Interaction	ATN1 interactions	ATN1 TLE1 AUTS2 RAD54L2 ZNF503	1.56e-04	187	55	5	int:ATN1
Interaction	KRTAP6-2 interactions	LGALS9C ATN1 PAX3 MEIS2 ZNF503	1.56e-04	187	55	5	int:KRTAP6-2
Interaction	QSER1 interactions	PAX8 GATA2 TBR1 HNRNPL	1.60e-04	100	55	4	int:QSER1
Interaction	PCGF5 interactions	PAX8 GATA2 AUTS2 HELZ	1.67e-04	101	55	4	int:PCGF5
Interaction	HNF1B interactions	LDB1 PAX8 TLE1 TBR1 ARID1A	1.68e-04	190	55	5	int:HNF1B
Interaction	FBRS interactions	GATA2 AUTS2 HELZ TBR1	1.73e-04	102	55	4	int:FBRS
Interaction	AUTS2 interactions	ATN1 AUTS2 HNRNPL	1.77e-04	40	55	3	int:AUTS2
Interaction	LHX1 interactions	LDB1 TLE1 SSBP3 ARID1A	1.80e-04	103	55	4	int:LHX1
Interaction	ADCY1 interactions	FZD7 HNRNPL	2.03e-04	8	55	2	int:ADCY1
Interaction	DAB1 interactions	LGALS9C LGALS9B MBNL3 HNRNPL	2.08e-04	107	55	4	int:DAB1
Interaction	ZFHX3 interactions	LDB1 GATA2 TBR1 HNRNPL	2.23e-04	109	55	4	int:ZFHX3
Interaction	PDCD6 interactions	RHBDD1 MAPK1IP1L PTPN23 FNDC3A ARID1A	2.33e-04	204	55	5	int:PDCD6
Interaction	PLCXD1 interactions	CECR2 HNRNPL	2.60e-04	9	55	2	int:PLCXD1
Interaction	BCL7C interactions	PAX8 GATA2 TBR1 ARID1A	2.74e-04	115	55	4	int:BCL7C
Interaction	TLE1 interactions	ATN1 PAX8 TLE1 GATA2 TBR1	2.85e-04	213	55	5	int:TLE1
Interaction	ALX4 interactions	LDB1 PAX3 HNRNPL	3.05e-04	48	55	3	int:ALX4
Interaction	BCL9L interactions	LDB1 TBR1 SSBP3	3.05e-04	48	55	3	int:BCL9L
Interaction	HMG20B interactions	PAX8 GATA2 TBR1 HNRNPL	3.43e-04	122	55	4	int:HMG20B
Interaction	SLC12A6 interactions	LGALS9C LGALS9B ERLIN1 HNRNPL	3.65e-04	124	55	4	int:SLC12A6
Interaction	NFIX interactions	PAX8 TLE1 TBR1 ARID1A HNRNPL	3.82e-04	227	55	5	int:NFIX
Interaction	ITCH interactions	RHBDD1 ATN1 ARID1A SF1 LDLRAD4 HNRNPL	4.07e-04	356	55	6	int:ITCH
Interaction	CIC interactions	LDB1 PAX8 GATA2 E2F7 PAX3 RAD54L2 TBR1 HNRNPL	4.51e-04	673	55	8	int:CIC
Interaction	ABCC4 interactions	LGALS9C LGALS9B HNRNPL	4.81e-04	56	55	3	int:ABCC4
Interaction	POU2AF1 interactions	PAX8 GATA2 MEIS2	4.81e-04	56	55	3	int:POU2AF1
Interaction	DCAF7 interactions	PAX8 GATA2 E2F7 AUTS2 RAD54L2 ZNF503	4.85e-04	368	55	6	int:DCAF7
Interaction	TOP3B interactions	FZD7 PPRC1 SHISA5 FOSL2 GATA2 HELZ ATG2A ARID1A ANKHD1 MYRF ABCA7 ZNF503	5.02e-04	1470	55	12	int:TOP3B
Interaction	NKX2-4 interactions	PAX8 TBR1	5.60e-04	13	55	2	int:NKX2-4
Interaction	NSUN5P1 interactions	ETV3 HELZ HNRNPL	5.61e-04	59	55	3	int:NSUN5P1
Interaction	SOX15 interactions	LDB1 TLE1 SSBP3 ARID1A	5.94e-04	141	55	4	int:SOX15
Interaction	TRPS1 interactions	PAX8 GATA2 TBR1 HNRNPL	6.26e-04	143	55	4	int:TRPS1
Interaction	IDI2 interactions	LDB1 SSBP3	6.52e-04	14	55	2	int:IDI2
Interaction	CRYBB3 interactions	ETV3 HELZ ANKHD1	6.80e-04	63	55	3	int:CRYBB3
Interaction	MAGI3 interactions	FZD7 LDLRAD4 HNRNPL	6.80e-04	63	55	3	int:MAGI3
Interaction	EWSR1 interactions	ATN1 MAPK1IP1L CECR2 ASH1L ETV3 SSBP3 ARID1A SF1 HNRNPL	7.12e-04	906	55	9	int:EWSR1
Interaction	PLEKHG7 interactions	GPD2 ETV3 HELZ ANKHD1	7.49e-04	150	55	4	int:PLEKHG7
Interaction	SH3YL1 interactions	HELZ HNRNPL	7.51e-04	15	55	2	int:SH3YL1
Interaction	GCM1 interactions	TLE1 ARID1A ZNF503	8.50e-04	68	55	3	int:GCM1
Interaction	MEGF6 interactions	ATN1 HNRNPL	8.56e-04	16	55	2	int:MEGF6
Interaction	SOX6 interactions	LDB1 TLE1 SSBP3 ZNF503	8.88e-04	157	55	4	int:SOX6
Interaction	ARID1A interactions	PAX8 GATA2 TBR1 ARID1A HNRNPL	9.24e-04	276	55	5	int:ARID1A
Interaction	SMYD3 interactions	HELZ MRPL24 HNRNPL	9.64e-04	71	55	3	int:SMYD3
Cytoband	Ensembl 112 genes in cytogenetic band chr10q24	LDB1 PPRC1 SEC31B ERLIN1	8.05e-05	189	55	4	chr10q24
GeneFamily	Paired boxes	PAX8 PAX3	1.53e-04	9	38	2	675
GeneFamily	Galectins	LGALS9C LGALS9B	4.44e-04	15	38	2	629
GeneFamily	Zinc fingers CCCH-type	HELZ MBNL3	2.45e-03	35	38	2	73
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	FZD7 ELFN1 KIAA1217 GATA2 E2F7 PAX3 FHDC1 TBR1 SEC31B SVEP1 MBNL3 ZNF503	1.81e-06	1074	55	12	M1941
Coexpression	MARSON_BOUND_BY_FOXP3_UNSTIMULATED	GPD2 FZD7 LDB1 SHISA5 FOSL2 ETV3 HELZ SSBP3 ARID1A ABCA7 SF1 HNRNPL	7.84e-06	1239	55	12	M1743
Coexpression	MARSON_BOUND_BY_FOXP3_UNSTIMULATED	GPD2 FZD7 LDB1 SHISA5 FOSL2 ETV3 HELZ SSBP3 ARID1A ABCA7 SF1 HNRNPL	1.06e-05	1277	55	12	MM1032
Coexpression	TABULA_MURIS_SENIS_GONADAL_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING	LGALS9C ATN1 LGALS9B SHISA5 FOSL2 SSBP3 MRPL24 TCF7L1 ZNF503	1.74e-05	720	55	9	MM3700
Coexpression	GENTILE_UV_HIGH_DOSE_DN	FZD7 TLE1 FOSL2 GATA2 AUTS2 MEIS2	3.14e-05	289	55	6	M13630
Coexpression	NAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN	GPD2 ATN1 TLE1 PAX3 SSBP3 ARID1A	3.46e-05	294	55	6	M41112
Coexpression	TABULA_MURIS_SENIS_BRAIN_NON_MYELOID_ASTROCYTE_AGEING	LGALS9C SFXN5 LGALS9B SHISA5 MAPK1IP1L FOSL2 FNDC3A	5.80e-05	474	55	7	MM3685
Coexpression	GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN	GPD2 PTPN23 FNDC3A PAX3 SF1	6.28e-05	200	55	5	M5132
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	ATN1 PPRC1 RAD54L2 SEC31B ABCA7 SF1	7.49e-05	338	55	6	M17094
Coexpression	TABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING	ATN1 SHISA5 MAPK1IP1L FOSL2 SSBP3 ARID1A TCF7L1 ZNF503	8.60e-05	685	55	8	MM3782
Coexpression	TABULA_MURIS_SENIS_AORTA_FIBROBLAST_OF_CARDIAC_TISSUE_AGEING	FZD7 ATN1 SHISA5 FOSL2 KIAA1217 HELZ FNDC3A MEIS2	1.25e-04	723	55	8	MM3672
CoexpressionAtlas	DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000	LDB1 NEUROD4 AUTS2 HELZ PAX3 SSBP3 ARID1A MYRF SF1 MEIS2 MBNL3 ZNF503	1.05e-06	843	54	12	gudmap_developingGonad_e11.5_testes_1000
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	ELFN1 FOSL2 KIAA1217 E2F7 FNDC3A DMRTA1 PAX3 ATG2A SEC31B MEIS2 ZNF503	2.61e-05	967	54	11	PCBC_ratio_ECTO_vs_MESO-5_cfr-2X-p05
CoexpressionAtlas	DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#5_top-relative-expression-ranked_1000	LDB1 AUTS2 HELZ SSBP3 ARID1A MYRF SF1 ZNF503	3.49e-05	498	54	8	gudmap_developingGonad_e11.5_testes_k5_1000
CoexpressionAtlas	ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#1	NEUROD4 DMRTA1 PAX3 SEC31B MEIS2 ZNF503	7.42e-05	279	54	6	ratio_ECTO_vs_SC_500_K1
CoexpressionAtlas	kidney_P2_CapMes_Crym_top-relative-expression-ranked_500	FZD7 PAX8 CECR2 TCF7L1 MEIS2 ERLIN1	9.35e-05	291	54	6	gudmap_kidney_P2_CapMes_Crym_500
CoexpressionAtlas	kidney single cell_e11.5_MetanephMesench_StemCellamp_k-means-cluster#2_top-relative-expression-ranked_200	SSBP3 TCF7L1 MEIS2	1.44e-04	40	54	3	gudmap_kidney single cell_e11.5_MetanephMesench_Scamp_k2_200
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	KIAA1217 ASH1L FNDC3A DMRTA1 SSBP3 ARID1A MEIS2 MBNL3 ZNF503	1.76e-04	804	54	9	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3	ELFN1 NEUROD4 DMRTA1 PAX3 SEC31B MEIS2 ZNF503	1.82e-04	471	54	7	ratio_ECTO_vs_SC_1000_K3
CoexpressionAtlas	ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500	NEUROD4 GATA2 DMRTA1 PAX3 SEC31B MEIS2 ZNF503	2.46e-04	495	54	7	PCBC_ratio_ECTO_vs_SC_500
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PAX8 TLE1 FOSL2 AUTS2 TCF7L1 LDLRAD4	1.28e-07	190	55	6	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LGALS9C LGALS9B TLE1 FOSL2 AUTS2	3.37e-06	186	55	5	c984e5729958237b101df96d1c89a236faacded6
ToppCell	10x5'-blood-Lymphocytic_NK-NK_CD16\|blood / Manually curated celltypes from each tissue	LGALS9B TLE1 FOSL2 AUTS2 HNRNPL	4.13e-06	194	55	5	c34a32f1cfe3e597cb0f91ba5bdd3e114e9f3d2e
ToppCell	10x5'-blood-Lymphocytic_NK\|blood / Manually curated celltypes from each tissue	LGALS9B TLE1 FOSL2 AUTS2 HNRNPL	4.24e-06	195	55	5	c1db871e8e8e8b8d6a5798bc43eaf54e102b75eb
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	KLHL29 FZD7 ELFN1 TCF7L1 MEIS2	4.24e-06	195	55	5	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	TLE1 KIAA1217 GATA2 MEIS2 ZNF503	4.79e-06	200	55	5	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	ELFN1 TLE1 GATA2 FHDC1 MEIS2	4.79e-06	200	55	5	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Cajal-Retzius\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ELFN1 DMRTA1 SVEP1 ZNF503	4.79e-05	162	55	4	1f589a763f3fd4e1e612809ef3903879d47dc1d8
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Cajal-Retzius\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	ELFN1 DMRTA1 SVEP1 ZNF503	4.90e-05	163	55	4	c1484e4de8b10e2f5fb14a7c02b2a015ffe0305e
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ETV3 ATG2A ABCA7 LDLRAD4	5.26e-05	166	55	4	c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	ETV3 HELZ ANKHD1 LDLRAD4	6.32e-05	174	55	4	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ELFN1 NEUROD4 DMRTA1 SVEP1	6.75e-05	177	55	4	84116796ca4c7007508c0f1a68a1135c7b922278
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL29 ELFN1 CECR2 FHDC1	6.90e-05	178	55	4	76e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL29 ELFN1 CECR2 FHDC1	6.90e-05	178	55	4	82f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCell	droplet-Lung-30m-Epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL29 ELFN1 CECR2 FHDC1	6.90e-05	178	55	4	5442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KLHL29 ELFN1 CECR2 FHDC1	6.90e-05	178	55	4	523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	CECR2 AUTS2 FHDC1 TCF7L1	7.21e-05	180	55	4	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	droplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL29 ELFN1 CECR2 FHDC1	7.36e-05	181	55	4	cadb18fc73031eb9f779599e15cd7861337fee78
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL29 ELFN1 CECR2 FHDC1	7.36e-05	181	55	4	85bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCell	10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GATA2 PTPN23 SSBP3 MEIS2	7.68e-05	183	55	4	f9a3af96c0fb7d5c4d7df6db8b2c42e322418c08
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TLE1 FOSL2 HELZ MYRF	8.01e-05	185	55	4	25781cf68e693e97dc1885e2879ab24fa946b51e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FOSL2 GATA2 FNDC3A TCF7L1	8.01e-05	185	55	4	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	LGALS9C LGALS9B TLE1 ATG2A	8.01e-05	185	55	4	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	CECR2 AUTS2 FHDC1 TCF7L1	8.70e-05	189	55	4	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIAA1217 AUTS2 SVEP1 MEIS2	9.25e-05	192	55	4	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 PPRC1 FOSL2 FNDC3A	9.25e-05	192	55	4	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	CECR2 AUTS2 FHDC1 TCF7L1	9.25e-05	192	55	4	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CECR2 AUTS2 FHDC1 TCF7L1	9.43e-05	193	55	4	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	CECR2 AUTS2 FHDC1 TCF7L1	9.43e-05	193	55	4	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CECR2 AUTS2 FHDC1 TCF7L1	9.43e-05	193	55	4	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-22\|World / Primary Cells by Cluster	KLHL29 AUTS2 FHDC1 MEIS2	9.43e-05	193	55	4	3b927d4b8ecb21a408424ef91a23746c21741f49
ToppCell	T_cells-CD56_dim_CD16+_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	LGALS9B FOSL2 SSBP3 MYRF	9.62e-05	194	55	4	335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell	mild_COVID-19\|World / disease group, cell group and cell class (v2)	MAPK1IP1L FOSL2 AUTS2 SF1	9.82e-05	195	55	4	6dbe9db5f0e94f2e91b3d1282855d200051ab0ba
ToppCell	facs-Skin-nan-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL29 FZD7 SVEP1 STPG4	9.82e-05	195	55	4	ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_NK\|lymph-node_spleen / Manually curated celltypes from each tissue	LGALS9B TLE1 FOSL2 AUTS2	1.00e-04	196	55	4	93ff94fc2b2ca8bd6a6492cbc0b402daf5d63ea2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	NEUROD4 AUTS2 FHDC1 MEIS2	1.00e-04	196	55	4	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	NEUROD4 AUTS2 FHDC1 MEIS2	1.00e-04	196	55	4	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LGALS9C LGALS9B TLE1 SSBP3	1.00e-04	196	55	4	9b3848dd4256cd6d9a21ef6bfdbd0cb7c0030005
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ELFN1 GATA2 SEC31B SF1	1.02e-04	197	55	4	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	T/NK_cells-CD56dim_NK_cell\|T/NK_cells / Lineage and Cell class	LGALS9C LGALS9B TLE1 FOSL2	1.02e-04	197	55	4	722d00a218755cc8cb7b5ab2a7fca40269247c3a
ToppCell	severe-Lymphocytic-NK_cells\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	LGALS9B FOSL2 AUTS2 SSBP3	1.04e-04	198	55	4	6ef22f33b43e9adceea11738e3cba0e8b59b4ec6
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 CECR2 AUTS2 TBR1	1.04e-04	198	55	4	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	mild_COVID-19-NK\|World / disease group, cell group and cell class (v2)	LGALS9B TLE1 FOSL2 AUTS2	1.04e-04	198	55	4	c0334e31772ab691be29cbaa78e43ee3b00425f5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LGALS9B TLE1 AUTS2 SSBP3	1.04e-04	198	55	4	eb5407908f1e43b5775d50006cc6c71e90b73660
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 CECR2 AUTS2 TBR1	1.04e-04	198	55	4	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	LGALS9B TLE1 AUTS2 SSBP3	1.04e-04	198	55	4	08e031cacded172bf85c8541b4724f97f19a0b99
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CECR2 AUTS2 FHDC1 TCF7L1	1.04e-04	198	55	4	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LGALS9B TLE1 AUTS2 SSBP3	1.04e-04	198	55	4	56a39e44c6f97b8093e3a3815b94a1ddf906f59d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CECR2 AUTS2 FHDC1 TCF7L1	1.04e-04	198	55	4	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-Neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	YDJC FHDC1 TBR1 MEIS2	1.04e-04	198	55	4	90ebefc9ba8dc2a81471e5693384f5ce56f06298
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK\|COVID-19_Mild / Disease group, lineage and cell class	LGALS9B TLE1 AUTS2 SSBP3	1.04e-04	198	55	4	52f9ed4b89bbce53104179bee194c0456c4b7a3c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LGALS9B TLE1 AUTS2 SSBP3	1.04e-04	198	55	4	a89de373e4287a104d4df2c40fb0e406d729b1df
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-OPC_related-Oligodendrocyte/OPC\|2m / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 AUTS2 PAX3 SSBP3	1.08e-04	200	55	4	3c9a2f02294a9fb892b89e856291bd6423ffa0a9
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Cortical_neuron\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	AUTS2 FHDC1 TBR1 MEIS2	1.08e-04	200	55	4	7bba2ff09349c8db3d1ccf53520b12cbf7b0abac
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-OPC_related\|2m / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 AUTS2 PAX3 SSBP3	1.08e-04	200	55	4	8e49e7e9b02d8411e4ffae1f5113a2c18f5bf179
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	AUTS2 FHDC1 MEIS2 HNRNPL	1.08e-04	200	55	4	fd6b4ff4330db11c03f1eb4e06b43a162326f744
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-GLP2R--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TLE1 FOSL2 KIAA1217 MEIS2	1.08e-04	200	55	4	dc8702e3cb4ac8c1a9849fc8abf8777f12d55b0b
ToppCell	mLN-Mast_cell-Mast\|mLN / Region, Cell class and subclass	GATA2 MEIS2 CD300C ZNF503	1.08e-04	200	55	4	81ea6e7a3940277751faf9097b30198159998c7b
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-GLP2R---L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TLE1 FOSL2 KIAA1217 MEIS2	1.08e-04	200	55	4	d92d51021ab6d78e9c8f89f7c150181004dcbcbd
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-GLP2R-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TLE1 FOSL2 KIAA1217 MEIS2	1.08e-04	200	55	4	cbbb9044283ff9ab63bbfc24d7a9f006b1372705
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	AUTS2 FHDC1 MEIS2 HNRNPL	1.08e-04	200	55	4	8795920911ee75c09a97cc948c14ad7301b27796
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ELFN1 TLE1 GATA2 MEIS2	1.08e-04	200	55	4	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK\|COVID-19_Mild / Disease, condition lineage and cell class	LGALS9B TLE1 AUTS2 SSBP3	1.08e-04	200	55	4	885fcb6c6c744f89fc983a617303e6f57126d908
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ASH1L HELZ SF1 HNRNPL	1.08e-04	200	55	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	mLN-Mast_cell\|mLN / Region, Cell class and subclass	GATA2 MEIS2 CD300C ZNF503	1.08e-04	200	55	4	9a5f1d99d8d160923d4d0fbbf9ad48a26f8a4fad
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIAA1217 GATA2 MEIS2 ZNF503	1.08e-04	200	55	4	f15fffefe372005c33e31845982e2d2714ac26af
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL29 SVEP1 MEIS2 ZNF503	1.08e-04	200	55	4	3dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIAA1217 GATA2 MEIS2 ZNF503	1.08e-04	200	55	4	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Neuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 DMRTA1 FHDC1 MEIS2	1.08e-04	200	55	4	3d134ae3c48ff4d1849db4fbe44ff73fb6c8c779
ToppCell	mLN-(7)_Mast_cell-(70)_Mast\|mLN / shred on region, Cell_type, and subtype	GATA2 MEIS2 CD300C ZNF503	1.08e-04	200	55	4	a6c258cae678be581b1d85cf3446c65c34b13499
ToppCell	COVID-19_Mild-NK\|COVID-19_Mild / Disease condition and Cell class	LGALS9B TLE1 FOSL2 AUTS2	1.08e-04	200	55	4	b586b0f1127293c2f8529be16b24229359041da2
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-GLP2R\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TLE1 FOSL2 KIAA1217 MEIS2	1.08e-04	200	55	4	a3e36bbeed19431d07bc205f14f4e0f12bd8f730
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / Treatment groups by lineage, cell group, cell type	ELFN1 TLE1 GATA2 MEIS2	1.08e-04	200	55	4	b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell	mLN-(7)_Mast_cell\|mLN / shred on region, Cell_type, and subtype	GATA2 MEIS2 CD300C ZNF503	1.08e-04	200	55	4	13bca944fbdbc0be6687eca82c62a4d231ab94f0
Drug	F-L-Leu	GPD2 PAX8 PPRC1 GATA2 E2F7	1.72e-06	83	55	5	CID000004308
Drug	ICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A	PAX8 NEUROD4 TLE1 AUTS2 FNDC3A SVEP1	7.04e-06	193	55	6	7490_UP
Drug	Ceforanide [60925-61-3]; Down 200; 7.6uM; PC3; HT_HG-U133A	TLE1 ASH1L GATA2 HELZ FNDC3A ARID1A	7.04e-06	193	55	6	6751_DN
Drug	Probenecid [57-66-9]; Up 200; 14uM; MCF7; HT_HG-U133A	ATN1 AUTS2 ARID1A LDLRAD4 SVEP1 MEIS2	7.26e-06	194	55	6	2825_UP
Drug	Trimeprazine tartrate [4330-99-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A	LDB1 FOSL2 RAD54L2 SF1 LDLRAD4 SVEP1	7.47e-06	195	55	6	3478_UP
Drug	Alverine citrate salt [5560-59-8]; Up 200; 8.4uM; PC3; HT_HG-U133A	LDB1 FOSL2 ASH1L TBR1 ARID1A ABCA7	8.15e-06	198	55	6	6345_UP
Drug	Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	GPD2 ASH1L GATA2 FNDC3A RAD54L2 MEIS2	8.39e-06	199	55	6	6209_DN
Drug	13-HODE	GPD2 PAX8 PPRC1 GATA2 E2F7	1.93e-05	136	55	5	CID000001424
Drug	9-HODE	GPD2 PAX8 PPRC1 GATA2 E2F7	2.38e-05	142	55	5	CID000001927
Drug	13-hydroxyoctadecanoic acid	GPD2 PAX8 PPRC1 GATA2	3.26e-05	75	55	4	CID005282911
Drug	Methotrexate [59-05-2]; Up 200; 8.8uM; MCF7; HT_HG-U133A	ATN1 FOSL2 ARID1A ABCA7 TCF7L1	8.83e-05	187	55	5	5419_UP
Drug	Azacyclonol [115-46-8]; Up 200; 15uM; PC3; HT_HG-U133A	FOSL2 GATA2 RAD54L2 ARID1A CD300C	9.06e-05	188	55	5	6298_UP
Drug	biochanin A	ATN1 PPRC1 FOSL2 LDLRAD4	1.05e-04	101	55	4	CID005280373
Drug	clofibrate; Up 200; 150uM; MCF7; HG-U133A	ATN1 PAX8 FOSL2 FNDC3A ARID1A	1.05e-04	194	55	5	263_UP
Drug	PF-00539758-00 [351321-34-1]; Up 200; 10uM; PC3; HT_HG-U133A	ATN1 FOSL2 ARID1A SVEP1 CD300C	1.08e-04	195	55	5	6379_UP
Drug	Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	FZD7 LDB1 TLE1 FNDC3A RAD54L2	1.10e-04	196	55	5	7226_DN
Drug	Trimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A	ATN1 PAX8 ASH1L MYRF SVEP1	1.10e-04	196	55	5	4100_DN
Drug	Piribedil hydrochloride [78213-63-5]; Up 200; 12uM; HL60; HT_HG-U133A	FZD7 RAD54L2 MYRF ABCA7 CD300C	1.10e-04	196	55	5	2951_UP
Drug	Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A	GPD2 PAX8 ARID1A SVEP1 CD300C	1.13e-04	197	55	5	3174_UP
Drug	Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A	ATN1 PAX3 LDLRAD4 SVEP1 CD300C	1.13e-04	197	55	5	6094_UP
Drug	Vancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; PC3; HT_HG-U133A	KLHL29 LDB1 ATN1 MYRF SVEP1	1.13e-04	197	55	5	4598_UP
Drug	Xylazine [7361-61-7]; Down 200; 18.2uM; PC3; HT_HG-U133A	PAX8 TLE1 FOSL2 LDLRAD4 SVEP1	1.13e-04	197	55	5	4066_DN
Drug	Etilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	FZD7 ATN1 TLE1 MEIS2 MBNL3	1.13e-04	197	55	5	7350_UP
Drug	Proglumide [6620-60-6]; Down 200; 12uM; PC3; HT_HG-U133A	GPD2 ATN1 FNDC3A MYRF SVEP1	1.13e-04	197	55	5	4337_DN
Drug	Glycopyrrolate [596-51-0]; Up 200; 10uM; PC3; HT_HG-U133A	ATN1 PAX8 TLE1 FOSL2 ASH1L	1.13e-04	197	55	5	3687_UP
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	ATN1 NEUROD4 ARID1A ABCA7 MBNL3	1.16e-04	198	55	5	2279_DN
Drug	Hecogenin [467-55-0]; Up 200; 9.2uM; PC3; HT_HG-U133A	ATN1 FOSL2 GATA2 FNDC3A RAD54L2	1.16e-04	198	55	5	5818_UP
Drug	Theophylline monohydrate [5967-84-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A	NEUROD4 AUTS2 ARID1A LDLRAD4 SVEP1	1.16e-04	198	55	5	3326_UP
Drug	Nimodipine [66085-59-4]; Up 200; 9.6uM; PC3; HT_HG-U133A	ATN1 RAD54L2 TBR1 ARID1A LDLRAD4	1.16e-04	198	55	5	6320_UP
Drug	AC1L1JLU	GPD2 PAX8 PPRC1 GATA2	1.17e-04	104	55	4	CID000005098
Drug	ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A_EA	LDB1 ATN1 TLE1 LDLRAD4 HNRNPL	1.18e-04	199	55	5	985_UP
Drug	Ricinine [524-40-3]; Down 200; 24.4uM; PC3; HT_HG-U133A	GPD2 LDB1 GATA2 RAD54L2 ABCA7	1.18e-04	199	55	5	5725_DN
Drug	(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	ATN1 PAX8 GATA2 MYRF LDLRAD4	1.18e-04	199	55	5	4016_DN
Drug	Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; PC3; HT_HG-U133A	ATN1 FOSL2 ARID1A ABCA7 LDLRAD4	1.18e-04	199	55	5	7362_UP
Drug	Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; MCF7; HT_HG-U133A	LDB1 ATN1 FOSL2 ABCA7 MBNL3	1.21e-04	200	55	5	3503_UP
Disease	lymphocyte percentage of leukocytes	CECR2 GATA2 HELZ YDJC DMRTA1 ARID1A ABCA7 TCF7L1	2.00e-05	665	52	8	EFO_0007993
Disease	Cardiovascular Abnormalities	ATN1 GATA2	3.60e-04	16	52	2	C0243050
Disease	leukemia (implicated_via_orthology)	ASH1L MEIS2	5.11e-04	19	52	2	DOID:1240 (implicated_via_orthology)
Disease	cortical surface area measurement	KLHL29 AUTS2 YDJC DMRTA1 PAX3 SSBP3 TCF7L1 SVEP1 MEIS2	5.18e-04	1345	52	9	EFO_0010736
Disease	neutrophil percentage of leukocytes	GATA2 HELZ DMRTA1 ARID1A ABCA7 TCF7L1	6.92e-04	610	52	6	EFO_0007990
Disease	spontaneous preterm birth	NEUROD4 KIAA1217 SVEP1	7.62e-04	101	52	3	EFO_0006917
Disease	Drugs used in diabetes use measurement	TLE1 AUTS2 DMRTA1 ERLIN1	1.06e-03	255	52	4	EFO_0009924
Disease	Iniencephaly	CECR2 PAX3	1.12e-03	28	52	2	C0152234
Disease	Tethered Cord Syndrome	CECR2 PAX3	1.12e-03	28	52	2	C0080218
Disease	Spinal Cord Myelodysplasia	CECR2 PAX3	1.12e-03	28	52	2	C0344479
Disease	Exencephaly	CECR2 PAX3	1.12e-03	28	52	2	C0266453
Disease	Neurenteric Cyst	CECR2 PAX3	1.12e-03	28	52	2	C0027806
Disease	Acrania	CECR2 PAX3	1.12e-03	28	52	2	C0702169
Disease	Diastematomyelia	CECR2 PAX3	1.12e-03	28	52	2	C0011999
Disease	Craniorachischisis	CECR2 PAX3	1.20e-03	29	52	2	C0152426
Disease	Neural Tube Defects	CECR2 PAX3	1.28e-03	30	52	2	C0027794
Disease	acylcarnitine measurement	KLHL29 RHBDD1 MYRF	1.48e-03	127	52	3	EFO_0005059
Disease	Burkitt Lymphoma	AUTS2 ARID1A	1.85e-03	36	52	2	C0006413
Disease	hepatocyte growth factor-like protein measurement	SHISA5 RAD54L2	2.06e-03	38	52	2	EFO_0008154
Disease	nasopharyngeal neoplasm	RHBDD1 ETV3 HELZ	2.42e-03	151	52	3	EFO_0004252
Disease	subiculum volume	SSBP3 MEIS2	2.63e-03	43	52	2	EFO_0009399
Disease	nasopharynx carcinoma (is_marker_for)	FOSL2 ARID1A	2.63e-03	43	52	2	DOID:9261 (is_marker_for)
Disease	childhood gender nonconformity	FOSL2 SSBP3	2.63e-03	43	52	2	EFO_0020103
Disease	pulse pressure measurement	KLHL29 LDB1 FOSL2 KIAA1217 GATA2 YDJC TCF7L1 SVEP1	2.85e-03	1392	52	8	EFO_0005763
Disease	Agents acting on the renin-angiotensin system use measurement	FOSL2 AUTS2 ARID1A SVEP1	2.88e-03	335	52	4	EFO_0009931

Protein segments in the cluster

Peptide	Gene	Start	Entry
SFTTPLPPPSYMHAG	ASH1L	1416	Q9NR48
PGPVPSPSTATHYIM	ELFN1	406	P0C7U0
PSGPGYHIMLPFITT	ERLIN1	46	O75477
RPGMYPDPHSPFAVS	ETV3	236	P41162
HPSVTPTGYHAPMEP	ATN1	186	P54259
HGYPVSGGFAMPPVS	RAD54L2	1286	Q9Y4B4
FPPHSVMLQTGPPYT	CECR2	1356	Q9BXF3
YVMSTGDLHPPPRPP	ATG2A	1236	Q2TAZ0
PPFGHYPALRLSPTM	ABCA7	1261	Q8IZY2
GYFPLSHPMTVAGPV	CD300C	21	Q08708
MVGPTLPGYPPHIPT	PAX8	366	Q06710
HAMPVAPGPALYPAP	PTPN23	811	Q9H3S7
HPPLAYGPAPSTRPM	PTPN23	1046	Q9H3S7
GIPPYGTLPPGRMSH	ARID1A	846	O14497
PPGLPPTTHMNGYSH	FHDC1	76	Q9C0D6
PSAGVHIVMPGYYSP	GPD2	311	P43304
PMYPPTYLEPGIGRH	LDB1	46	Q86U70
HPAYPMPFITTIPGG	LGALS9C	221	Q6DKI2
ASMYGDPHAPRPIPP	MEIS2	21	O14770
HPAYPMPFITTIPGG	LGALS9B	221	Q3B8N2
HSYPPAVSGIPPMIP	AUTS2	581	Q8WXX7
NHLMGPGFPYGLPPL	HELZ	1691	P42694
FNHLIPGGFPPTAMP	PAX3	286	P23760
MGTQPATHHPIPTYP	GATA2	236	P23769
PPGHFPPMSPDFTVF	FZD7	516	O75084
FPVLYSPAMPGPVSS	E2F7	756	Q96AV8
PPPRHMYSPVTGAGD	FNDC3A	131	Q9Y2H6
FMSPYLTPGLVPTLP	DMRTA1	451	Q5VZB9
PYSPLPGLASVPGHM	FOSL2	81	P15408
FNPYIPHPGMGLVPA	MBNL3	131	Q9NUK0
PPPEYGPHADSPVLM	HNRNPL	371	P14866
IPIMSHTGNPPVPYP	KLF17	166	Q5JT82
MGPVLPDPFTHYAPL	PPRC1	906	Q5VV67
MESLSPGGPPGHPYQ	PLA2G4D	1	Q86XP0
TVPFGPAPTGMYPSV	MAPK1IP1L	61	Q8NDC0
PHSQPFMSPRYAGGP	SSBP3	146	Q9BWW4
SPPPYGFHLSPEEMR	RHBDD1	291	Q8TEB9
SAMFPYPGQHGPAHP	TBR1	121	Q16650
HSMPPSPSRIPYGGT	KIAA1217	321	Q5T5P2
GYHTMPPQPGMPAAP	SHISA5	176	Q8N114
PAMPLAPSHPSPYQG	SEC31B	841	Q9NQW1
MEVPYVTPHPPYHLG	SVEP1	2641	Q4LDE5
PPHYRYGMSPPGSVA	MRPL24	16	Q96A35
MSYFRTPQTHPGPLP	SPATA25	1	Q9BR10
PISMYGGTIIPSHPQ	ANKHD1	2471	Q8IWZ3
GPYPAPFGMVPHAGM	TLE1	366	Q04724
VAYGRSPMVGFDPPP	TLE1	411	Q04724
GQPMYSLPPGGFRHP	TCF7L1	256	Q9HCS4
GPGPGHYNVKMPPTS	STPG4	176	Q8N801
ELMAHPGYPSVPPTG	YDJC	241	A8MPS7
GQTVFPLPPAGMTYP	ZNF503	346	Q96F45
PFRMSGYIPFGTPIV	SFXN5	106	Q8TD22
HHGPPPMDQYLGSTP	SF1	441	Q15637
PHVGPQLPLMPGHYS	KLHL29	191	Q96CT2
PPPTYSEVMGHHPGA	LDLRAD4	251	O15165
PPIPHYAAMGQGLVP	MYRF	211	Q9Y2G1
SPGLPSPPYGHMETH	NEUROD4	206	Q9HD90