| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | ZNF597 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZSCAN12 ZNF613 HDAC4 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 ZNF658B CASZ1 STAT6 ZNF771 SP8 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 KLF18 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF880 ZNF510 ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 SMAD4 ZNF124 ZNF304 | 1.07e-41 | 1459 | 226 | 88 | GO:0000977 |
| GeneOntologyMolecularFunction | RNA polymerase II cis-regulatory region sequence-specific DNA binding | ZNF597 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZSCAN12 ZNF613 HDAC4 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 ZNF658B STAT6 ZNF771 SP8 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 KLF18 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF211 ZNF48 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF880 ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF197 ZFP1 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 SMAD4 ZNF304 | 1.75e-39 | 1244 | 226 | 80 | GO:0000978 |
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | ZNF597 SP2 SP3 SP4 ZNF845 ZNF140 ZFP42 ZNF143 ZNF586 ZSCAN12 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 ZNF658B CASZ1 STAT6 ZNF771 SP8 ZNF600 ZNF320 ZNF394 WIZ ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 KLF18 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF880 ZNF510 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 SMAD4 ZNF124 ZNF304 | 4.17e-39 | 1412 | 226 | 84 | GO:0000981 |
| GeneOntologyMolecularFunction | cis-regulatory region sequence-specific DNA binding | ZNF597 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZSCAN12 ZNF613 HDAC4 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 ZNF658B STAT6 ZNF771 SP8 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 KLF18 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF211 ZNF48 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF880 ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF197 ZFP1 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 SMAD4 ZNF304 | 8.38e-39 | 1271 | 226 | 80 | GO:0000987 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity, RNA polymerase II-specific | ZNF597 ZNF845 ZFP42 ZNF143 ZNF658 ZNF227 RREB1 ZNF658B CASZ1 STAT6 ZNF771 ZNF600 GLI2 GLIS2 PLAGL2 ZNF615 ZFP62 ZNF574 ZNF48 ZNF484 WT1 ZNF300 ZNF850 ZNF786 HINFP ZNF668 ZNF197 SMAD4 | 4.74e-11 | 560 | 226 | 28 | GO:0001228 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity | ZNF597 ZNF845 ZFP42 ZNF143 ZNF658 ZNF227 RREB1 ZNF658B CASZ1 STAT6 ZNF771 ZNF600 GLI2 GLIS2 PLAGL2 ZNF615 ZFP62 ZNF574 ZNF48 ZNF484 WT1 ZNF300 ZNF850 ZNF786 HINFP ZNF668 ZNF197 SMAD4 | 6.07e-11 | 566 | 226 | 28 | GO:0001216 |
| GeneOntologyMolecularFunction | peptide alpha-N-acetyltransferase activity | NAA10 NAA80 NAA11 | 7.68e-05 | 8 | 226 | 3 | GO:0004596 |
| GeneOntologyMolecularFunction | peptide-glutamate-alpha-N-acetyltransferase activity | NAA10 NAA11 | 1.28e-04 | 2 | 226 | 2 | GO:1990190 |
| GeneOntologyMolecularFunction | N-acylphosphatidylethanolamine-specific phospholipase D activity | PLD1 PLD2 | 3.80e-04 | 3 | 226 | 2 | GO:0070290 |
| GeneOntologyMolecularFunction | peptide-serine-alpha-N-acetyltransferase activity | NAA10 NAA11 | 3.80e-04 | 3 | 226 | 2 | GO:1990189 |
| GeneOntologyBiologicalProcess | positive regulation of transcription by RNA polymerase II | ZNF597 SP3 ZNF845 ZFP42 ZNF143 HDAC4 ZNF658 MAZ ZNF227 RREB1 ZNF658B CASZ1 STAT6 ZNF462 PRDM9 ZNF600 GLI2 GLIS2 PLAGL2 ZNF615 ZFP62 IQCE ZNF574 ZNF48 ZNF484 WT1 ZNF300 ZNF407 ZNF850 ZNF786 RBCK1 HINFP ZNF668 PPARGC1B ZNF197 ZFHX3 SMAD4 ZNF304 | 1.23e-07 | 1390 | 224 | 38 | GO:0045944 |
| GeneOntologyBiologicalProcess | N-terminal protein amino acid acetylation | NAA10 NAA80 NAA35 NAA11 | 2.22e-05 | 16 | 224 | 4 | GO:0006474 |
| GeneOntologyCellularComponent | N-terminal protein acetyltransferase complex | NAA10 NAA35 NAA11 | 1.34e-04 | 10 | 222 | 3 | GO:0031414 |
| Domain | ZnF_C2H2 | ZNF597 BNC2 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 CASZ1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 ZFR2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF385A ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 DHX34 ZNF124 ZNF304 | 5.68e-68 | 808 | 221 | 93 | SM00355 |
| Domain | zf-C2H2 | ZNF597 BNC2 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZNF143 ZNF586 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 CASZ1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 ZNF124 ZNF304 | 1.14e-67 | 693 | 221 | 88 | PF00096 |
| Domain | Znf_C2H2-like | ZNF597 BNC2 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 CASZ1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 ZFR2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF385A ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 DHX34 ZNF124 ZNF304 | 2.57e-67 | 796 | 221 | 92 | IPR015880 |
| Domain | ZINC_FINGER_C2H2_2 | ZNF597 BNC2 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 CASZ1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF385A ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 ZNF124 ZNF304 | 4.02e-67 | 775 | 221 | 91 | PS50157 |
| Domain | ZINC_FINGER_C2H2_1 | ZNF597 BNC2 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 CASZ1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF385A ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 ZNF124 ZNF304 | 5.09e-67 | 777 | 221 | 91 | PS00028 |
| Domain | Znf_C2H2 | ZNF597 BNC2 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 CASZ1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 ZFR2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF385A ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 ZNF124 ZNF304 | 7.22e-67 | 805 | 221 | 92 | IPR007087 |
| Domain | - | ZNF597 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 ZNF124 ZNF304 | 7.16e-66 | 679 | 221 | 86 | 3.30.160.60 |
| Domain | Znf_C2H2/integrase_DNA-bd | ZNF597 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF70 SP5 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 ZNF124 ZNF304 | 4.76e-65 | 694 | 221 | 86 | IPR013087 |
| Domain | zf-C2H2_6 | ZNF597 ZNF845 ZNF671 ZNF140 ZNF586 ZNF613 ZNF658 ZKSCAN8 ZNF227 RREB1 ZNF771 PRDM9 ZNF600 ZNF320 ZNF497 ZNF530 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF316 ZNF880 ZNF865 ZNF850 ZNF546 ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF197 ZNF561 ZNF761 ZNF543 ZBTB11 | 2.92e-38 | 314 | 221 | 47 | PF13912 |
| Domain | KRAB | ZNF597 ZNF845 ZNF671 ZNF140 ZNF586 ZNF613 ZNF658 ZKSCAN8 ZNF214 ZNF227 ZSCAN25 PRDM9 ZNF320 ZNF394 ZNF530 ZNF324 ZNF479 ZNF480 ZNF616 ZNF615 ZNF860 ZNF468 ZNF211 ZNF560 ZNF484 ZNF316 ZNF300 ZNF343 ZNF880 ZNF510 ZNF850 ZNF786 ZNF546 ZNF2 ZNF10 ZNF514 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZNF747 ZNF561 ZNF761 ZNF543 ZNF124 ZNF304 | 3.89e-36 | 369 | 221 | 48 | SM00349 |
| Domain | KRAB | ZNF597 ZNF845 ZNF671 ZNF140 ZNF586 ZNF613 ZNF658 ZKSCAN8 ZNF214 ZNF227 ZSCAN25 PRDM9 ZNF320 ZNF394 ZNF530 ZNF324 ZNF479 ZNF480 ZNF616 ZNF615 ZNF860 ZNF468 ZNF211 ZNF560 ZNF484 ZNF316 ZNF300 ZNF343 ZNF880 ZNF510 ZNF850 ZNF786 ZNF546 ZNF2 ZNF10 ZNF514 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZNF747 ZNF561 ZNF761 ZNF543 ZNF124 ZNF304 | 4.43e-36 | 370 | 221 | 48 | IPR001909 |
| Domain | KRAB | ZNF597 ZNF845 ZNF671 ZNF140 ZNF586 ZNF613 ZNF658 ZKSCAN8 ZNF214 ZNF227 PRDM9 ZNF320 ZNF394 ZNF530 ZNF324 ZNF479 ZNF480 ZNF616 ZNF615 ZNF860 ZNF468 ZNF211 ZNF560 ZNF484 ZNF316 ZNF300 ZNF343 ZNF880 ZNF510 ZNF850 ZNF786 ZNF546 ZNF2 ZNF10 ZNF514 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZNF747 ZNF561 ZNF761 ZNF543 ZNF124 ZNF304 | 1.47e-35 | 358 | 221 | 47 | PF01352 |
| Domain | KRAB | ZNF597 ZNF845 ZNF671 ZNF140 ZNF586 ZNF613 ZNF658 ZKSCAN8 ZNF214 ZNF227 ZNF320 ZNF394 ZNF530 ZNF324 ZNF479 ZNF480 ZNF616 ZNF615 ZNF860 ZNF468 ZNF211 ZNF560 ZNF484 ZNF316 ZNF300 ZNF343 ZNF880 ZNF510 ZNF850 ZNF786 ZNF546 ZNF2 ZNF10 ZNF514 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZNF747 ZNF561 ZNF761 ZNF543 ZNF124 ZNF304 | 2.29e-34 | 358 | 221 | 46 | PS50805 |
| Domain | Sp1_fam | SP2 SP3 SP4 SP8 SP5 | 5.32e-08 | 10 | 221 | 5 | IPR030450 |
| Domain | SCAN | ZNF165 ZKSCAN8 ZSCAN25 ZNF394 ZNF449 ZSCAN31 ZNF197 | 4.19e-06 | 56 | 221 | 7 | SM00431 |
| Domain | SCAN_BOX | ZNF165 ZKSCAN8 ZSCAN25 ZNF394 ZNF449 ZSCAN31 ZNF197 | 5.32e-06 | 58 | 221 | 7 | PS50804 |
| Domain | SCAN | ZNF165 ZKSCAN8 ZSCAN25 ZNF394 ZNF449 ZSCAN31 ZNF197 | 5.32e-06 | 58 | 221 | 7 | PF02023 |
| Domain | SCAN_dom | ZNF165 ZKSCAN8 ZSCAN25 ZNF394 ZNF449 ZSCAN31 ZNF197 | 5.32e-06 | 58 | 221 | 7 | IPR003309 |
| Domain | Retrov_capsid_C | ZNF165 ZKSCAN8 ZSCAN25 ZNF394 ZNF449 ZSCAN31 ZNF197 | 5.98e-06 | 59 | 221 | 7 | IPR008916 |
| Domain | K_chnl_inward-rec_Kir2.2 | KCNJ12 KCNJ18 | 1.39e-04 | 2 | 221 | 2 | IPR003272 |
| Domain | PLipase_D1/D2 | PLD1 PLD2 | 1.39e-04 | 2 | 221 | 2 | IPR016555 |
| Domain | PLipase_D_fam | PLD1 PLD2 | 1.39e-04 | 2 | 221 | 2 | IPR015679 |
| Domain | Znf_U1 | ZFR2 ZNF407 ZNF385A ZFHX3 | 3.59e-04 | 29 | 221 | 4 | IPR003604 |
| Domain | ZnF_U1 | ZFR2 ZNF407 ZNF385A ZFHX3 | 3.59e-04 | 29 | 221 | 4 | SM00451 |
| Domain | PH | OBSCN AFAP1L1 PLD1 PLD2 PLEKHA7 ARHGAP21 AGAP1 TIAM1 ARHGEF4 PLEKHO1 | 4.14e-04 | 229 | 221 | 10 | PF00169 |
| Domain | K_chnl_inward-rec_Kir_N | KCNJ12 KCNJ18 | 4.15e-04 | 3 | 221 | 2 | IPR013673 |
| Domain | PLDc_2 | PLD1 PLD2 | 4.15e-04 | 3 | 221 | 2 | PF13091 |
| Domain | PLD-like_dom | PLD1 PLD2 | 4.15e-04 | 3 | 221 | 2 | IPR025202 |
| Domain | IRK_N | KCNJ12 KCNJ18 | 4.15e-04 | 3 | 221 | 2 | PF08466 |
| Domain | PLDc | PLD1 PLD2 | 8.23e-04 | 4 | 221 | 2 | PF00614 |
| Pathway | REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION | ZNF597 ZNF671 ZNF140 ZNF143 ZNF586 ZNF613 KMT2B HDAC4 ZNF658 ZKSCAN8 BARD1 ZNF214 ZNF227 ZSCAN25 BCL6 DDB2 ZNF771 ZNF600 ZNF320 ZNF394 ZNF530 GLI2 ZNF324 ZNF479 ZNF480 ZNF616 ZNF615 ZNF860 ZNF468 ZNF775 ZNF211 ZNF560 ZNF484 ZNF300 ZNF343 ZNF510 SIN3A ZNF385A ZNF786 ZNF546 ZNF2 ZNF10 ZNF514 ZNF668 PPARGC1B ZNF26 ZNF334 ZNF37A CBX6 ZNF45 ZNF197 ZFP1 ZNF747 ZNF70 ZNF561 ZFHX3 ZNF761 ZNF543 SMAD4 ZNF124 ZNF304 | 4.42e-21 | 1387 | 165 | 61 | M734 |
| Pubmed | Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells. | ZNF845 ZNF140 ZKSCAN8 ZNF227 ZNF320 ZNF324 ZNF480 ZNF615 ZNF468 ZNF211 ZNF316 ZNF45 ZNF197 ZFP1 ZNF561 ZNF543 ZBTB11 ZNF124 | 3.03e-16 | 181 | 229 | 18 | 37372979 |
| Pubmed | Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. | BNC2 SP2 SP3 SP4 ZNF143 ZSCAN12 ZKSCAN8 ZNF462 ZNF394 WIZ GLIS2 ZNF324 ZNF616 PLAGL2 KLF11 ZNF775 ZNF48 WT1 ZNF300 ZNF385A ZNF786 ZNF2 HINFP ZNF668 ZNF334 ZFHX3 SMAD4 | 5.79e-12 | 808 | 229 | 27 | 20412781 |
| Pubmed | The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. | ZNF597 USP34 ZNF845 ZNF143 ZSCAN12 ZNF658 MAZ ZKSCAN8 ZNF227 DDB2 CASZ1 ZNF462 ZNF771 NAA35 ZNF320 GLI2 RBM15B ZNF468 ZFP62 ZNF574 USP13 RPL36 ZNF316 ZNF407 SIN3A ZNF850 ZNF668 LRP1 ZNF70 LRPAP1 ZNF525 | 1.01e-10 | 1203 | 229 | 31 | 29180619 |
| Pubmed | Mammalian SP/KLF transcription factors: bring in the family. | SP2 SP3 SP4 SP8 KLF11 SP5 | 1.22e-08 | 25 | 229 | 6 | 15820306 |
| Pubmed | Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. | USP34 KMT2B ERC1 BCORL1 ZNF217 KEAP1 RREB1 ZNF462 WIZ ARHGAP21 HUWE1 ZBTB10 LRP1 ZFHX3 ZBTB11 PCNT | 2.22e-08 | 418 | 229 | 16 | 34709266 |
| Pubmed | Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells. | SP2 SP3 SP4 SP5 | 2.72e-08 | 6 | 229 | 4 | 16201967 |
| Pubmed | O-GlcNAc modification of Sp3 and Sp4 transcription factors negatively regulates their transcriptional activities. | SP2 SP3 SP4 | 2.82e-07 | 3 | 229 | 3 | 26431879 |
| Pubmed | Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease. | USP34 ERC1 ZNF214 ZNF227 DCAF5 STAT6 WIZ USP32 AMOTL2 UROD ARHGAP21 AGAP1 USP13 DMXL2 POLG ZNF343 HUWE1 RBCK1 THOP1 ZNF334 TIAM1 ZNF197 LRP1 LRPAP1 ZBTB11 PCNT | 4.37e-07 | 1285 | 229 | 26 | 35914814 |
| Pubmed | Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. | KIF21B ZSCAN12 HDAC4 ERC1 TRPC4 KEAP1 ZNF462 MDN1 ZNF394 WIZ UNC79 ARHGAP21 DMXL2 HUWE1 SLC1A3 TXLNA ICAM5 LRP1 ADGRA1 RIMS1 SSH2 PCNT | 4.91e-07 | 963 | 229 | 22 | 28671696 |
| Pubmed | Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. | ZSCAN12 ZNF165 ZKSCAN8 | 1.12e-06 | 4 | 229 | 3 | 9244436 |
| Pubmed | Three novel spermatogenesis-specific zinc finger genes. | ZSCAN12 ZNF394 ZNF45 | 1.12e-06 | 4 | 229 | 3 | 12860387 |
| Pubmed | Sp2 is the only glutamine-rich specificity protein with minor impact on development and differentiation in myelinating glia. | SP2 SP3 SP4 | 1.12e-06 | 4 | 229 | 3 | 27889927 |
| Pubmed | Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. | ZNF227 ZNF462 WIZ ZNF324 ZNF45 ZFP1 ZNF747 | 1.33e-06 | 83 | 229 | 7 | 20562864 |
| Pubmed | Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity. | USP34 ERC1 MAZ KEAP1 RREB1 DCAF5 ZNF771 NAA35 WIZ ZNF324 PLD1 ZNF574 GOPC ZNF316 SIN3A ZNF526 VANGL1 ZFP1 ZBTB10 LRP1 ZFHX3 DHX34 UNC80 | 1.55e-06 | 1116 | 229 | 23 | 31753913 |
| Pubmed | Multiple genes encoding zinc finger domains are expressed in human T cells. | ZNF10 ZNF26 ZNF37A ZNF45 ZFP1 | 1.75e-06 | 31 | 229 | 5 | 2288909 |
| Pubmed | Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter. | SP2 SP3 SP4 | 2.79e-06 | 5 | 229 | 3 | 10547281 |
| Pubmed | Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells. | NCF1 PLD1 PLD2 | 2.79e-06 | 5 | 229 | 3 | 19366706 |
| Pubmed | A census of human transcription factors: function, expression and evolution. | SP2 SP3 SP4 ZNF143 MAZ BCL6 RREB1 STAT6 GLI2 PLAGL2 KLF11 WT1 ZNF385A HINFP ZNF26 ZNF37A ZNF197 SP5 ZFHX3 SMAD4 | 2.88e-06 | 908 | 229 | 20 | 19274049 |
| Pubmed | Impact of cytosine methylation on DNA binding specificities of human transcription factors. | ZNF597 SP2 SP3 ZNF140 ZFP42 BCL6 ZNF771 SP8 GLI2 GLIS2 ZNF449 KLF11 ZSCAN31 ZNF343 ZFP1 | 3.79e-06 | 544 | 229 | 15 | 28473536 |
| Pubmed | Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. | SP3 SP4 HDAC4 KEAP1 GLI2 PLEKHA7 WNK4 IQCE WT1 SIN3A PLEKHO1 PCNT ZNF304 | 6.40e-06 | 430 | 229 | 13 | 35044719 |
| Pubmed | An atlas of combinatorial transcriptional regulation in mouse and man. | ZNF597 SP2 ZFP42 HDAC4 BARD1 BCL6 STAT6 SP8 PLAGL2 ZSCAN31 WT1 ZNF407 SIN3A ZNF2 PPARGC1B CBX6 ZNF747 ZNF70 SMAD4 | 6.50e-06 | 877 | 229 | 19 | 20211142 |
| Pubmed | Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. | ACSS1 DCAF5 ZNF462 WDR97 ADGRA1 HYDIN UNC80 | 7.30e-06 | 107 | 229 | 7 | 11347906 |
| Pubmed | Multi-omics profiling visualizes dynamics of cardiac development and functions. | SP4 MAZ KLF11 | 9.67e-06 | 7 | 229 | 3 | 36577384 |
| Pubmed | POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1. | SP3 SP4 BCL6 | 9.67e-06 | 7 | 229 | 3 | 12004059 |
| Pubmed | The in vivo Interaction Landscape of Histones H3.1 and H3.3. | ZNF845 KMT2B MAZ BCORL1 ZKSCAN8 BARD1 RREB1 CASZ1 ZNF462 WIZ UNG SIN3A ZFP1 ZBTB10 ZBTB11 | 1.42e-05 | 608 | 229 | 15 | 36089195 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | USP34 KMT2B OBSCN SFI1 CNTROB CASZ1 MDN1 WIZ ARHGAP21 PKN3 IQCE ZNF48 POLG ZNF316 ARHGAP17 HUWE1 ZNF865 MROH6 ARHGEF4 DHX34 PCNT | 1.53e-05 | 1105 | 229 | 21 | 35748872 |
| Pubmed | Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? | MDN1 UNC79 USP13 GARNL3 HUWE1 TIAM1 SOCS5 HYDIN | 1.83e-05 | 170 | 229 | 8 | 23314748 |
| Pubmed | Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. | SP2 ACSS1 SYTL2 CASZ1 ZNF462 ZNF616 DMXL2 ZNF407 ZNF526 SOCS5 SSH2 TMCC1 UNC80 | 2.69e-05 | 493 | 229 | 13 | 15368895 |
| Pubmed | FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia. | KIF21B MRPL23 OBSCN MDN1 USP32 SCN9A UNG ARHGAP21 WNK4 ZNF211 ACAD9 EIF2AK4 HYDIN | 2.93e-05 | 497 | 229 | 13 | 36774506 |
| Pubmed | Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. | USP34 LGMN OBSCN UNC13D DCAF5 STAT6 ZNF600 PLD1 PLEKHA7 ARHGAP21 ACAD9 POLG PHTF2 HUWE1 SLC1A3 THOP1 SOCS5 ZBTB10 EIF2AK4 PCNT | 3.71e-05 | 1084 | 229 | 20 | 11544199 |
| Pubmed | Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation. | HDAC4 ZKSCAN8 ST6GALNAC6 ZNF574 ZNF449 RPL36 ZNF2 SOCS5 ZNF747 TMCC1 | 3.84e-05 | 305 | 229 | 10 | 21244100 |
| Pubmed | Cloning, characterization, and expression analysis of the novel acetyltransferase retrogene Ard1b in the mouse. | NAA10 NAA11 | 4.32e-05 | 2 | 229 | 2 | 19246321 |
| Pubmed | Genomic analysis of murine phospholipase D1 and comparison to phospholipase D2 reveals an unusual difference in gene size. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 9813240 |
| Pubmed | Mono- and Poly-unsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine Cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 32814056 |
| Pubmed | Functional analysis of mammalian phospholipase D enzymes. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 30369483 |
| Pubmed | Differential regulation of apoptosis by caspase-mediated cleavage of phospholipase D isozymes. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 18694819 |
| Pubmed | Increased phospholipase D activity contributes to tumorigenesis in prostate cancer cell models. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 32661773 |
| Pubmed | Phospholipase D is involved in the formation of Golgi associated clathrin coated vesicles in human parotid duct cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 24618697 |
| Pubmed | Phospholipase D is essential for keratocyte-like migration of NBT-II cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 18344600 |
| Pubmed | Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 12615079 |
| Pubmed | Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching. | BCL6 STAT6 | 4.32e-05 | 2 | 229 | 2 | 10490661 |
| Pubmed | Metabolism of activated complement component C3 is mediated by the low density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor. | C3 LRP1 | 4.32e-05 | 2 | 229 | 2 | 10608878 |
| Pubmed | Exosome Secretion and Epithelial-Mesenchymal Transition in Ovarian Cancer Are Regulated by Phospholipase D. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 36362078 |
| Pubmed | Platelet derived growth factor increases phospholipase D1 but not phospholipase D2 expression via NFkappaB signaling pathway and enhances invasion of breast cancer cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 20188462 |
| Pubmed | 39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 1718973 |
| Pubmed | Organization and alternative splicing of the murine phospholipase D2 gene. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 9560313 |
| Pubmed | STAT6 and LRP1 polymorphisms are associated with food allergen sensitization in Mexican children. | STAT6 LRP1 | 4.32e-05 | 2 | 229 | 2 | 22534531 |
| Pubmed | Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 32209478 |
| Pubmed | Cross-talk between phospholipase D and MAP kinases activities. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 19896495 |
| Pubmed | Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 3266596 |
| Pubmed | A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 1374383 |
| Pubmed | β-1,3-Glucan-induced host phospholipase D activation is involved in Aspergillus fumigatus internalization into type II human pneumocyte A549 cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 21760893 |
| Pubmed | HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion. | HUWE1 TIAM1 | 4.32e-05 | 2 | 229 | 2 | 25543140 |
| Pubmed | Overexpressed PLAGL2 transcriptionally activates Wnt6 and promotes cancer development in colorectal cancer. | PLAGL2 WNT6 | 4.32e-05 | 2 | 229 | 2 | 30535429 |
| Pubmed | Pharmacological inhibition of phospholipase D protects mice from occlusive thrombus formation and ischemic stroke--brief report. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 23868933 |
| Pubmed | The transcription factor Sp3 regulates the expression of a metastasis-related marker of sarcoma, actin filament-associated protein 1-like 1 (AFAP1L1). | SP3 AFAP1L1 | 4.32e-05 | 2 | 229 | 2 | 23326307 |
| Pubmed | Phospholipase D isoforms differentially regulate leukocyte responses to acute lung injury. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 29437245 |
| Pubmed | Cloning and initial characterization of a human phospholipase D2 (hPLD2). ADP-ribosylation factor regulates hPLD2. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 9582313 |
| Pubmed | Low-density lipoprotein receptor-related protein polymorphisms in patients with elevated factor VIII coagulant activity and venous thrombosis. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 16175004 |
| Pubmed | PLD1 promotes reactive oxygen species production in vascular smooth muscle cells and injury-induced neointima formation. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 34610470 |
| Pubmed | PLD1 and PLD2 differentially regulate the balance of macrophage polarization in inflammation and tissue injury. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 33368247 |
| Pubmed | The phospholipase D pathway mediates the inflammatory response of the retinal pigment epithelium. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 25172550 |
| Pubmed | Role of Kir2.2 in hypercapnic ventilatory response during postnatal development of mouse. | KCNJ12 KCNJ18 | 4.32e-05 | 2 | 229 | 2 | 15705530 |
| Pubmed | Importance of PLD2 in an IL-23 driven psoriasiform dermatitis model and potential link to human psoriasis. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 37455419 |
| Pubmed | Phospholipase D1 and D2 Synergistically Regulate Thrombus Formation. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 32971863 |
| Pubmed | Involvement of Phospholipase D 1 and 2 in the subcellular localization and activity of formyl-peptide-receptors in the human colonic cell line HT29. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 19707939 |
| Pubmed | Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. | SP2 SP3 | 4.32e-05 | 2 | 229 | 2 | 1341900 |
| Pubmed | Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 31090437 |
| Pubmed | An mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation. | KLF11 SIN3A | 4.32e-05 | 2 | 229 | 2 | 12970187 |
| Pubmed | Phospholipase D in human platelets: presence of isoenzymes and participation of autocrine stimulation during thrombin activation. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 18432522 |
| Pubmed | Differential expression of the alpha(2)-macroglobulin receptor and the receptor associated protein in normal human endometrium and endometrial carcinoma. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 11006321 |
| Pubmed | Deubiquitinase USP13 promotes extracellular matrix expression by stabilizing Smad4 in lung fibroblast cells. | USP13 SMAD4 | 4.32e-05 | 2 | 229 | 2 | 32434004 |
| Pubmed | Molecular chaperone RAP interacts with LRP1 in a dynamic bivalent mode and enhances folding of ligand-binding regions of other LDLR family receptors. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 34058195 |
| Pubmed | Dominant thermodynamic role of the third independent receptor binding site in the receptor-associated protein RAP. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 11735425 |
| Pubmed | Phagocyte cell migration is mediated by phospholipases PLD1 and PLD2. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 16873675 |
| Pubmed | Generation of choline for acetylcholine synthesis by phospholipase D isoforms. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 11734063 |
| Pubmed | Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 23383154 |
| Pubmed | STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL). | BCL6 STAT6 | 4.32e-05 | 2 | 229 | 2 | 23852366 |
| Pubmed | Characterization of human PLD2 and the analysis of PLD isoform splice variants. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 9761774 |
| Pubmed | The molecular basis of leukocyte adhesion involving phosphatidic acid and phospholipase D. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 25187519 |
| Pubmed | Phospholipase D in TCR-Mediated Signaling and T Cell Activation. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 29386256 |
| Pubmed | Phospholipase D1 is a regulator of platelet-mediated inflammation. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 28711718 |
| Pubmed | Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorage-independent growth of colorectal cancer cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 20711340 |
| Pubmed | Key roles for the lipid signaling enzyme phospholipase d1 in the tumor microenvironment during tumor angiogenesis and metastasis. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 23131846 |
| Pubmed | Phospholipase D: A new mediator during high phosphate-induced vascular calcification associated with chronic kidney disease. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 30207376 |
| Pubmed | Redundant functions of phospholipases D1 and D2 in platelet α-granule release. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 22974101 |
| Pubmed | Phospholipase D is a target for inhibition of astroglial proliferation by ethanol. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 24262632 |
| Pubmed | The influence of polyunsaturated fatty acids on the phospholipase D isoforms trafficking and activity in mast cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 23698760 |
| Pubmed | Phosphatidic acid, phospholipase D and tumorigenesis. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 24103483 |
| Pubmed | High Affinity Binding of the Receptor-associated Protein D1D2 Domains with the Low Density Lipoprotein Receptor-related Protein (LRP1) Involves Bivalent Complex Formation: CRITICAL ROLES OF LYSINES 60 AND 191. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 27402839 |
| Pubmed | Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 25523098 |
| Pubmed | Phospholipase D messenger RNA expression and clinical role in high-grade serous carcinoma. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 28087476 |
| Pubmed | Impaired brain development and reduced cognitive function in phospholipase D-deficient mice. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 24813107 |
| Pubmed | Differential expression of phospholipases D1 and D2 in mouse tissues. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 17085061 |
| Pubmed | Histone deacetylase 4 mediates SMAD family member 4 deacetylation and induces 5-fluorouracil resistance in breast cancer cells. | HDAC4 SMAD4 | 4.32e-05 | 2 | 229 | 2 | 23817620 |
| Pubmed | The YXXL motif, but not the two NPXY motifs, serves as the dominant endocytosis signal for low density lipoprotein receptor-related protein. | LRP1 LRPAP1 | 4.32e-05 | 2 | 229 | 2 | 10747918 |
| Pubmed | Transcriptional repression of cyclin-dependent kinase inhibitor p21 gene by phospholipase D1 and D2. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 12782287 |
| Pubmed | Structure and regulation of human phospholipase D. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 33495125 |
| Pubmed | Phospholipases D1 and D2 Suppress Appetite and Protect against Overweight. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 27299737 |
| Pubmed | Expression of MARCKS effector domain mutants alters phospholipase D activity and cytoskeletal morphology of SK-N-MC neuroblastoma cells. | PLD1 PLD2 | 4.32e-05 | 2 | 229 | 2 | 16341931 |
| Interaction | NOTCH2 interactions | SP2 MAZ ZKSCAN8 ZSCAN25 ZNF771 ZNF320 ZNF497 PXDN ZNF324 ZNF480 ZNF574 ZNF775 ZNF48 ZNF316 ZNF407 SIN3A ZNF865 ZNF668 ZNF526 CBX6 ZNF747 ZNF761 | 2.24e-09 | 423 | 224 | 22 | int:NOTCH2 |
| Interaction | LTBP2 interactions | ZNF320 ZNF497 ZNF324 ZNF480 PLD1 ZNF574 ZNF775 ZNF316 ZNF865 ZNF526 ZNF747 | 2.60e-09 | 85 | 224 | 11 | int:LTBP2 |
| Interaction | CACNG5 interactions | ZNF324 PLD1 PLD2 ZNF574 ZNF775 ZNF316 ZNF865 | 3.11e-07 | 41 | 224 | 7 | int:CACNG5 |
| Interaction | TRIM28 interactions | ZNF845 ZNF140 ZFP42 HDAC4 ZNF658 ZKSCAN8 KEAP1 ZNF227 STAT6 ZNF462 ZNF600 ZNF320 ZNF324 ZNF480 ZNF616 ZNF615 ZNF468 ZNF211 ZNF484 ZNF316 SIN3A HUWE1 ZNF2 ZNF10 ZNF514 ZNF26 ZNF37A ZNF45 ZNF197 ZFP1 ZNF747 ZNF561 ZNF761 ZNF543 ZBTB11 DHX34 ZNF124 ZNF304 | 9.42e-07 | 1474 | 224 | 38 | int:TRIM28 |
| Interaction | ZNF169 interactions | ZKSCAN8 ZSCAN25 ZNF324 ZNF316 ZNF865 ZNF45 ZBTB10 | 2.17e-06 | 54 | 224 | 7 | int:ZNF169 |
| Interaction | ZBTB47 interactions | ZSCAN25 ZNF394 ZNF616 ZFP62 ZNF574 ZNF48 ZNF668 MRPS2 ZNF70 ZBTB11 | 4.94e-06 | 144 | 224 | 10 | int:ZBTB47 |
| Interaction | ZNF467 interactions | ZNF845 ZKSCAN8 ZNF320 ZNF324 ZNF480 ZFP62 ZNF574 ZNF211 ZNF48 ZNF668 ZNF761 | 5.41e-06 | 179 | 224 | 11 | int:ZNF467 |
| Interaction | CEP70 interactions | ZNF140 ZSCAN12 HDAC4 ZNF165 BARD1 ZNF227 ZNF860 IQCE ZNF574 ZNF775 WT1 ZFP1 ZFHX3 | 7.96e-06 | 262 | 224 | 13 | int:CEP70 |
| Interaction | ZNF121 interactions | ZKSCAN8 BARD1 KEAP1 ZNF48 ZNF2 CBX6 | 1.14e-05 | 46 | 224 | 6 | int:ZNF121 |
| Interaction | XAGE2 interactions | ZNF462 WIZ POT1 THOP1 | 1.84e-05 | 15 | 224 | 4 | int:XAGE2 |
| Interaction | GOLGA6L9 interactions | HDAC4 ZNF165 ZNF497 GLIS2 ZNF479 C3 ZNF574 ZNF48 ZFP1 ZFHX3 ZNF124 | 3.15e-05 | 216 | 224 | 11 | int:GOLGA6L9 |
| Interaction | PHF21A interactions | USP34 SP3 KMT2B ERC1 BCORL1 ZNF217 KEAP1 RREB1 ARHGAP21 PKN3 HUWE1 ZFHX3 ZBTB11 PCNT | 3.20e-05 | 343 | 224 | 14 | int:PHF21A |
| Interaction | TRIM41 interactions | ZNF165 ZNF497 ZNF575 PLAGL2 ZNF574 ZNF48 ZNF343 ZNF2 ZNF526 ZNF26 ZFP1 | 4.22e-05 | 223 | 224 | 11 | int:TRIM41 |
| Interaction | OASL interactions | ZNF845 ZKSCAN8 ZSCAN25 ZNF771 ZNF616 ZNF574 ACAD9 ZNF316 ZNF865 ZNF668 ZBTB11 | 4.22e-05 | 223 | 224 | 11 | int:OASL |
| Interaction | ELK3 interactions | SP2 SP4 KMT2B BCORL1 ZNF217 RREB1 WIZ ZBTB10 | 5.94e-05 | 120 | 224 | 8 | int:ELK3 |
| Interaction | ZNF397 interactions | ZSCAN12 ZKSCAN8 ZNF394 RPL36 ZNF26 ZNF197 | 6.45e-05 | 62 | 224 | 6 | int:ZNF397 |
| Interaction | MTUS2 interactions | ZSCAN12 ZNF613 HDAC4 BARD1 BCL6 ZNF497 C2CD6 PKN3 IQCE ZNF775 ZNF48 ZFP1 ZFHX3 ZNF124 | 7.25e-05 | 370 | 224 | 14 | int:MTUS2 |
| Interaction | SMARCAD1 interactions | ZFP42 ZNF214 MDN1 WIZ ZNF324 ZNF211 ZNF484 SIN3A HUWE1 ZNF514 | 7.42e-05 | 197 | 224 | 10 | int:SMARCAD1 |
| Interaction | CBX6 interactions | BCORL1 ZKSCAN8 ZNF214 ZNF771 RPL36 ZNF316 PCDHB3 ZNF668 CBX6 ZNF70 ZBTB11 DDX28 | 8.22e-05 | 283 | 224 | 12 | int:CBX6 |
| Interaction | ZSCAN20 interactions | ZKSCAN8 ZSCAN25 ZNF394 C3 ZNF449 ZNF197 | 8.43e-05 | 65 | 224 | 6 | int:ZSCAN20 |
| Interaction | CARD10 interactions | ZNF613 ZNF165 KEAP1 ZSCAN25 ZNF575 ZNF775 ZNF10 ZFP1 | 8.87e-05 | 127 | 224 | 8 | int:CARD10 |
| Interaction | RNF4 interactions | ZNF597 USP34 ZNF845 ZFP42 ZNF143 ZSCAN12 ZNF658 MAZ ZKSCAN8 ZNF227 DDB2 CASZ1 ZNF462 ZNF771 NAA35 ZNF320 GLI2 RBM15B ZNF468 ZFP62 ZNF574 USP13 RPL36 ZNF316 ZNF407 SIN3A ZNF850 ZNF668 LRP1 ZNF70 LRPAP1 ZNF525 | 9.44e-05 | 1412 | 224 | 32 | int:RNF4 |
| Interaction | CBX3 interactions | KMT2B BCORL1 BARD1 ZNF217 ZNF227 RREB1 ZNF462 WIZ ZNF324 ZNF615 KLF11 ZNF316 ZNF850 ZNF10 THOP1 CBX6 ZFP1 ZNF747 HDLBP | 1.17e-04 | 646 | 224 | 19 | int:CBX3 |
| Interaction | CCDC136 interactions | HDAC4 BARD1 ZNF497 WT1 ZNF865 TXLNA ZNF197 ZFP1 ZNF124 | 1.18e-04 | 169 | 224 | 9 | int:CCDC136 |
| Interaction | ZFP62 interactions | ZFP3 GLI2 ZFP62 RPL36 ZNF48 ZNF2 ZNF668 | 1.19e-04 | 99 | 224 | 7 | int:ZFP62 |
| Interaction | DHX57 interactions | HDAC4 ZKSCAN8 NAA10 BARD1 PLAGL2 ZNF574 ZSCAN31 R3HDM2 ZNF668 CBX6 HDLBP | 1.26e-04 | 252 | 224 | 11 | int:DHX57 |
| Interaction | SCAND1 interactions | ZSCAN12 ZNF165 ZKSCAN8 ZSCAN25 ZNF394 ZNF449 | 1.28e-04 | 70 | 224 | 6 | int:SCAND1 |
| Interaction | ZSCAN32 interactions | ZSCAN12 ZKSCAN8 KEAP1 ZNF394 ZNF197 | 1.38e-04 | 45 | 224 | 5 | int:ZSCAN32 |
| Interaction | RBM4B interactions | ZNF845 DDB2 ZNF320 ZNF324 ZNF574 ACAD9 ZNF668 CBX6 ZNF761 ZBTB11 HDLBP | 1.77e-04 | 262 | 224 | 11 | int:RBM4B |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19q13 | ZNF845 ZNF671 ZNF586 ZNF613 KMT2B ZNF227 ZNF600 ZNF320 ZNF497 ZNF530 ZNF575 ZNF324 ZNF480 ZNF616 ZNF615 ZNF468 ZNF574 ZNF211 ZNF880 ZNF865 ZNF850 ZNF546 ZNF526 ZNF45 ZNF525 ZNF761 ZNF543 DHX34 ZNF304 | 2.53e-12 | 1192 | 229 | 29 | chr19q13 |
| Cytoband | 19q13.41 | ZNF613 ZNF600 ZNF320 ZNF480 ZNF616 ZNF615 ZNF468 ZNF880 | 5.89e-09 | 78 | 229 | 8 | 19q13.41 |
| Cytoband | 19q13.43 | ZNF671 ZNF586 ZNF497 ZNF530 ZNF324 ZNF543 | 5.20e-06 | 87 | 229 | 6 | 19q13.43 |
| GeneFamily | Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes | ZNF597 BNC2 SP2 SP3 SP4 ZNF845 ZNF671 ZNF140 ZFP42 ZNF143 ZNF586 ZSCAN12 ZNF613 ZFP3 ZNF658 ZNF165 MAZ ZKSCAN8 ZNF214 ZNF217 ZNF227 ZSCAN25 BCL6 RREB1 CASZ1 ZNF462 ZNF771 SP8 PRDM9 ZNF600 ZNF320 ZNF497 ZNF394 WIZ ZNF530 GLI2 GLIS2 ZNF575 ZNF324 ZNF479 ZNF480 ZNF616 PLAGL2 ZNF615 ZNF860 ZNF468 ZFP62 ZNF574 ZNF449 KLF11 ZNF775 ZNF211 ZNF48 ZNF560 ZSCAN31 ZNF484 ZNF316 WT1 ZNF300 ZNF343 ZNF407 ZNF880 ZNF510 ZNF865 ZNF850 ZNF786 ZNF546 ZNF2 HINFP ZNF10 ZNF514 ZNF668 ZNF526 ZNF26 ZNF334 ZNF37A ZNF45 ZNF197 ZFP1 ZBTB10 ZNF747 ZNF70 SP5 ZNF525 ZNF561 ZFHX3 ZNF761 ZNF543 ZNF853 ZBTB11 ZNF124 ZNF304 | 5.07e-78 | 718 | 189 | 92 | 28 |
| GeneFamily | Zinc fingers C2H2-type|Sp transcription factors | SP2 SP3 SP4 SP8 SP5 | 1.44e-08 | 9 | 189 | 5 | 755 |
| GeneFamily | N(alpha)-acetyltransferase subunits|GCN5 related N-acetyltransferases | NAA10 NAA35 NAA11 | 2.31e-04 | 12 | 189 | 3 | 660 |
| GeneFamily | Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing | AFAP1L1 PLD1 PLEKHA7 ARHGAP21 AGAP1 TIAM1 ARHGEF4 PLEKHO1 | 1.49e-03 | 206 | 189 | 8 | 682 |
| GeneFamily | GCN5 related N-acetyltransferases | NAA10 NAA80 NAA11 | 1.94e-03 | 24 | 189 | 3 | 1134 |
| ToppCell | kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | ZNF320 PXDN ZNF615 WT1 PCDHB3 PHTF2 LRP1 STAG3 | 3.57e-06 | 175 | 229 | 8 | 12f5fd83c7710fc0c77406f765d9cbd133433b8b |
| ToppCell | 368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells) | MRPL23 SP2 ZNF845 ZNF586 UNG SPATA6L SIN3A ZNF525 | 5.16e-06 | 184 | 229 | 8 | 9cbfb9f09476b4d09eb8f92c6f21e449dabcfa98 |
| ToppCell | LPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | ZNF165 DDB2 MDN1 ZNF616 C3 ZNF316 DDX28 | 6.13e-06 | 134 | 229 | 7 | 64979e1a056b7406e1be39c5ebe2f8d731ac3c17 |
| ToppCell | Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | ZNF597 ZNF671 ZNF143 PTHLH ZNF615 ZNF449 DDX28 SMAD4 | 8.20e-06 | 196 | 229 | 8 | 7e98380d815fbf6254289ace2af37aac6fef51e8 |
| ToppCell | 10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue | LGMN MID1 ZNF775 GARNL3 ZNF300 ZNF546 ZNF2 | 8.56e-06 | 141 | 229 | 7 | 7671d300b1722711fd2d8034b96a3aa7e3ccb560 |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | SP2 ZNF140 CASZ1 ZNF575 SPATA6L ZNF48 POLG DDX28 | 9.16e-06 | 199 | 229 | 8 | 26bb93347e6722abd174dfa62cab692ce2b7eb23 |
| Drug | vinylene | SP4 ZFP42 MAZ ZNF462 SP8 ZNF394 GLIS2 ZNF324 ZNF480 PLAGL2 KLF11 WT1 ZNF300 ZNF197 ZNF304 | 2.70e-08 | 245 | 227 | 15 | CID000006326 |
| Drug | Brinzolamide [138890-62-7]; Down 200; 10.4uM; PC3; HT_HG-U133A | ZNF671 SYTL2 WIZ C3 PLD2 PHTF2 TIAM1 ZNF197 ZNF747 ARHGEF4 DHX34 | 4.44e-06 | 195 | 227 | 11 | 6670_DN |
| Drug | Liothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A | MAZ ZNF214 PLD2 PHTF2 ZNF510 THOP1 LRP1 ARHGEF4 PLEKHO1 DDX28 SMAD4 | 4.67e-06 | 196 | 227 | 11 | 6602_DN |
| Drug | palladium | SP2 SP3 MID1 UNG UROD ZNF2 PAM | 5.16e-06 | 68 | 227 | 7 | CID000023938 |
| Disease | Ogden syndrome (implicated_via_orthology) | NAA10 NAA11 | 5.33e-05 | 2 | 216 | 2 | DOID:0050781 (implicated_via_orthology) |
| Disease | developmental cardiac valvular defect (implicated_via_orthology) | PLD1 PLD2 | 5.33e-05 | 2 | 216 | 2 | DOID:0080633 (implicated_via_orthology) |
| Disease | Idiopathic pulmonary arterial hypertension | HDAC4 EIF2AK4 SMAD4 | 2.02e-04 | 16 | 216 | 3 | C3203102 |
| Disease | C-reactive protein measurement | USP34 BNC2 SP3 NCF1 RIPOR3 CCDC168 ZNF227 RREB1 DDB2 HSPA12A PXDN PLD2 ARHGAP21 DMXL2 ZNF316 R3HDM2 MROH6 CBX6 THNSL2 ZNF853 HDLBP | 2.27e-04 | 1206 | 216 | 21 | EFO_0004458 |
| Disease | Familial primary pulmonary hypertension | HDAC4 EIF2AK4 SMAD4 | 2.44e-04 | 17 | 216 | 3 | C0340543 |
| Disease | Brachydactyly | HDAC4 SMAD4 | 3.17e-04 | 4 | 216 | 2 | C0221357 |
| Disease | Chromosome 2q37 deletion syndrome | HDAC4 HDLBP | 3.17e-04 | 4 | 216 | 2 | C2931817 |
| Disease | freckles | BNC2 HSPA12A PPARGC1B | 4.02e-04 | 20 | 216 | 3 | EFO_0003963 |
| Disease | mitogen-activated protein kinase 3 measurement | ZNF771 ZNF48 | 5.26e-04 | 5 | 216 | 2 | EFO_0020579 |
| Disease | low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram | ZFP42 ZFHX3 RIMS1 | 6.99e-04 | 24 | 216 | 3 | EFO_0004611, EFO_0006329, EFO_0007871 |
| Disease | Cerebral ventriculomegaly | SIN3A HYDIN | 1.09e-03 | 7 | 216 | 2 | C1531647 |
| Disease | Hydrocephalus Ex-Vacuo | SIN3A HYDIN | 1.09e-03 | 7 | 216 | 2 | C0270720 |
| Disease | Communicating Hydrocephalus | SIN3A HYDIN | 1.09e-03 | 7 | 216 | 2 | C0009451 |
| Disease | Fetal Cerebral Ventriculomegaly | SIN3A HYDIN | 1.09e-03 | 7 | 216 | 2 | C2936718 |
| Disease | Post-Traumatic Hydrocephalus | SIN3A HYDIN | 1.09e-03 | 7 | 216 | 2 | C0477432 |
| Disease | Obstructive Hydrocephalus | SIN3A HYDIN | 1.09e-03 | 7 | 216 | 2 | C0549423 |
| Disease | RS-10-hydroxywarfarin to RS-warfarin ratio measurement | TAS2R9 ARHGAP21 SPATA6L EIF2AK4 SMAD4 | 1.32e-03 | 110 | 216 | 5 | EFO_0803335 |
| Disease | Congenital Hydrocephalus | SIN3A HYDIN | 1.45e-03 | 8 | 216 | 2 | C0020256 |
| Disease | Aqueductal Stenosis | SIN3A HYDIN | 1.45e-03 | 8 | 216 | 2 | C2936786 |
| Disease | diabetes mellitus | RREB1 NUCB2 ZFP1 PAM | 1.58e-03 | 68 | 216 | 4 | EFO_0000400 |
| Disease | Nonorganic psychosis | SP8 ZSCAN31 TDO2 PCNT | 1.66e-03 | 69 | 216 | 4 | C0349204 |
| Disease | Idiopathic pulmonary hypertension | EIF2AK4 SMAD4 | 1.86e-03 | 9 | 216 | 2 | C0152171 |
| Disease | Hydrocephalus | SIN3A HYDIN | 1.86e-03 | 9 | 216 | 2 | C0020255 |
| Disease | membranous glomerulonephritis (implicated_via_orthology) | C3 LRPAP1 | 1.86e-03 | 9 | 216 | 2 | DOID:10976 (implicated_via_orthology) |
| Disease | blood urea nitrogen measurement | RREB1 DDB2 CASZ1 ZNF462 WNT9B PHTF2 R3HDM2 LINC02694 DHX34 HCRTR2 | 1.94e-03 | 452 | 216 | 10 | EFO_0004741 |
| Disease | balding measurement | SP3 HDAC4 KRT74 UNC13D RREB1 PTHLH CASZ1 ZNF462 GLI2 MAP3K14 SLC1A3 LRP1 PAM HDLBP | 2.22e-03 | 792 | 216 | 14 | EFO_0007825 |
| Disease | Pulmonary arterial hypertension | EIF2AK4 SMAD4 | 2.31e-03 | 10 | 216 | 2 | C2973725 |
| Disease | congenital diaphragmatic hernia (implicated_via_orthology) | WT1 LRP1 | 3.35e-03 | 12 | 216 | 2 | DOID:3827 (implicated_via_orthology) |
| Disease | age at onset, alcohol dependence | CASZ1 ZNF407 LINC02694 | 3.60e-03 | 42 | 216 | 3 | EFO_0004847, MONDO_0007079 |
| Disease | Profound Mental Retardation | HDAC4 STRA6 SIN3A ZNF526 BBS7 | 3.65e-03 | 139 | 216 | 5 | C0020796 |
| Disease | Mental Retardation, Psychosocial | HDAC4 STRA6 SIN3A ZNF526 BBS7 | 3.65e-03 | 139 | 216 | 5 | C0025363 |
| Disease | Mental deficiency | HDAC4 STRA6 SIN3A ZNF526 BBS7 | 3.65e-03 | 139 | 216 | 5 | C0917816 |
| Disease | intercellular adhesion molecule 5 measurement | KEAP1 ICAM5 | 3.95e-03 | 13 | 216 | 2 | EFO_0008164 |
| Disease | 2-oxo-hept-3-ene-1,7-dioate hydratase activity | EIF2AK4 SMAD4 | 4.58e-03 | 14 | 216 | 2 | C1150929 |
| Disease | anxiety, stress-related disorder, major depressive disorder | ZSCAN12 ZKSCAN8 ZSCAN31 | 4.66e-03 | 46 | 216 | 3 | EFO_0005230, EFO_0010098, MONDO_0002009 |
| Disease | Gastrointestinal Stromal Sarcoma | GLI2 GLIS2 ZBTB11 | 4.95e-03 | 47 | 216 | 3 | C3179349 |
| Disease | pulmonary function measurement, smoking behaviour measurement, FEV/FEC ratio | HDAC4 BCL6 LRP1 | 4.95e-03 | 47 | 216 | 3 | EFO_0003892, EFO_0004713, EFO_0005671 |
| Disease | red blood cell density measurement | SP3 SP4 ZNF217 RREB1 CASZ1 ZNF462 KCNJ12 AGAP1 KLF11 R3HDM2 CCDC92 EIF2AK4 SSH2 HCRTR2 | 5.61e-03 | 880 | 216 | 14 | EFO_0007978 |
| Disease | Malignant neoplasm of breast | HDAC4 TRPC4 BCORL1 OBSCN BARD1 KEAP1 PTHLH PLD2 WT1 ZNF546 ZNF668 PPARGC1B TRMT10A ICAM5 ARHGEF4 HDLBP | 5.87e-03 | 1074 | 216 | 16 | C0006142 |
| Disease | Gastrointestinal Stromal Tumors | GLI2 GLIS2 ZBTB11 | 5.89e-03 | 50 | 216 | 3 | C0238198 |
| Disease | Paroxysmal atrial fibrillation | USP34 CASZ1 ZNF462 GOPC ZFHX3 | 5.93e-03 | 156 | 216 | 5 | C0235480 |
| Disease | familial atrial fibrillation | USP34 CASZ1 ZNF462 GOPC ZFHX3 | 5.93e-03 | 156 | 216 | 5 | C3468561 |
| Disease | Persistent atrial fibrillation | USP34 CASZ1 ZNF462 GOPC ZFHX3 | 5.93e-03 | 156 | 216 | 5 | C2585653 |
| Disease | behavioural inhibitory control measurement | STRA6 ZBTB10 | 5.98e-03 | 16 | 216 | 2 | EFO_0008467 |
| Disease | Psychotic Disorders | SP8 ZSCAN31 TDO2 PCNT | 6.56e-03 | 101 | 216 | 4 | C0033975 |
| Disease | non-high density lipoprotein cholesterol measurement | USP34 N4BP2L1 BNC2 KEAP1 PKN3 ZNF574 R3HDM2 CCDC92 RBCK1 THOP1 THNSL2 HYDIN | 6.58e-03 | 713 | 216 | 12 | EFO_0005689 |
| Disease | Atrial Fibrillation | USP34 CASZ1 ZNF462 GOPC ZFHX3 | 6.59e-03 | 160 | 216 | 5 | C0004238 |
| Disease | creatinine measurement | KIF21B OBSCN RREB1 CASZ1 USP32 PLEKHA7 MAP3K14 PHTF2 R3HDM2 SIN3A SLC1A3 ZFHX3 LINC02694 UNC80 HCRTR2 | 6.80e-03 | 995 | 216 | 15 | EFO_0004518 |
| Disease | pulse pressure measurement | USP34 BNC2 UNC13D RREB1 PTHLH CASZ1 PRDM9 PLEKHA7 GOPC WNT9B NUCB2 WT1 PHTF2 LRP1 ZFHX3 EIF2AK4 LINC02694 DHX34 HYDIN | 6.97e-03 | 1392 | 216 | 19 | EFO_0005763 |
