Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-1,4-glucosidase activity

MGAM GANC

7.14e-055542GO:0004558
GeneOntologyMolecularFunctionalpha-glucosidase activity

MGAM GANC

1.49e-047542GO:0090599
GeneOntologyMolecularFunctiondeacetylase activity

MIER3 NDST2 MIER1

1.72e-0440543GO:0019213
GeneOntologyMolecularFunctionpotassium channel inhibitor activity

WNK3 WNK2

3.89e-0411542GO:0019870
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

MIER3 NDST2 CDADC1 MIER1

6.53e-04146544GO:0016810
GeneOntologyMolecularFunctionglucosidase activity

MGAM GANC

7.37e-0415542GO:0015926
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

MIER3 NDST2 MIER1

1.37e-0381543GO:0016811
GeneOntologyMolecularFunctionhistone deacetylase activity

MIER3 MIER1

1.91e-0324542GO:0004407
GeneOntologyMolecularFunctionprotein lysine deacetylase activity

MIER3 MIER1

2.07e-0325542GO:0033558
GeneOntologyBiologicalProcessmaltose metabolic process

MGAM GANC

1.94e-053532GO:0000023
MousePhenoepididymis epithelium degeneration

BMP8B BMP8A

2.90e-053442MP:0004934
DomainKinase_OSR1/WNK_CCT

WNK3 WNK2

1.22e-046542IPR024678
DomainOSR1_C

WNK3 WNK2

1.22e-046542PF12202
DomainGlyco_hydro_31_AS

MGAM GANC

1.22e-046542IPR030458
DomainGlyco_hydro_31

MGAM GANC

1.71e-047542IPR000322
DomainGlyco_hydro_31

MGAM GANC

1.71e-047542PF01055
DomainGLYCOSYL_HYDROL_F31_1

MGAM GANC

1.71e-047542PS00129
DomainER_TARGET

HSP90B1 RCN1 RCN2

3.39e-0447543PS00014
DomainInhibin_asu

BMP8B BMP8A

6.27e-0413542IPR002405
DomainELM2

MIER3 MIER1

6.27e-0413542PF01448
DomainELM2

MIER3 MIER1

6.27e-0413542PS51156
DomainELM2_dom

MIER3 MIER1

6.27e-0413542IPR000949
DomainELM2

MIER3 MIER1

6.27e-0413542SM01189
DomainGal_mutarotase_SF_dom

MGAM GANC

1.09e-0317542IPR011013
DomainbZIP_2

CEBPD TEF

1.09e-0317542PF07716
DomainEF-hand_5

RCN1 RCN2

2.36e-0325542PF13202
DomainSANT_dom

MIER3 MIER1

2.55e-0326542IPR017884
DomainSANT

MIER3 MIER1

2.96e-0328542PS51293
DomainTGFb_propeptide

BMP8B BMP8A

2.96e-0328542PF00688
DomainTGF-b_N

BMP8B BMP8A

2.96e-0328542IPR001111
DomainTGF-beta-rel

BMP8B BMP8A

3.85e-0332542IPR015615
DomainTGFb_CS

BMP8B BMP8A

3.85e-0332542IPR017948
DomainMyb_DNA-binding

MIER3 MIER1

4.59e-0335542PF00249
DomainTGFB

BMP8B BMP8A

5.12e-0337542SM00204
DomainTGF-b_C

BMP8B BMP8A

5.12e-0337542IPR001839
DomainTGF_BETA_2

BMP8B BMP8A

5.12e-0337542PS51362
DomainTGF_beta

BMP8B BMP8A

5.12e-0337542PF00019
DomainTGF_BETA_1

BMP8B BMP8A

5.12e-0337542PS00250
DomainSANT

MIER3 MIER1

9.20e-0350542SM00717
DomainBRLZ

CEBPD TEF

9.92e-0352542SM00338
DomainSANT/Myb

MIER3 MIER1

9.92e-0352542IPR001005
DomainBZIP

CEBPD TEF

1.03e-0253542PS50217
DomainBZIP_BASIC

CEBPD TEF

1.03e-0253542PS00036
DomainGlycoside_hydrolase_SF

MGAM GANC

1.03e-0253542IPR017853
DomainbZIP

CEBPD TEF

1.07e-0254542IPR004827
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

SBNO1 ZC3H4 CPSF6 G3BP2 RCN1 RCN2 BAZ1B BUB3 MIER1

6.87e-0765354933742100
Pubmed

PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas.

PIM1 BCL6

2.37e-06254222451912
Pubmed

Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.

BMP8B BMP8A

2.37e-06254231940275
Pubmed

Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.

BMP8B BMP8A

2.37e-0625429463357
Pubmed

The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

2.37e-0625428682296
Pubmed

The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells.

BMP8B BMP8A

2.37e-06254221277400
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

CACTIN MDN1 MAPT ZC3H4 BAZ1B BUB3 MN1 MIER1 AGTPBP1

2.78e-0677454915302935
Pubmed

The functional interactome landscape of the human histone deacetylase family.

MDN1 MIER3 RCN1 RCN2 BAZ1B MIER1

5.78e-0628954623752268
Pubmed

Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

7.09e-0635429076678
Pubmed

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).

BMP8B BMP8A

7.09e-06354212925636
Pubmed

Requirement of Bmp8b for the generation of primordial germ cells in the mouse.

BMP8B BMP8A

7.09e-06354210894154
Pubmed

WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway.

WNK3 WNK2

7.09e-06354218768590
Pubmed

BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions.

BMP8B BMP8A

7.09e-06354222579288
Pubmed

Mutation in Bmp7 exacerbates the phenotype of Bmp8a mutants in spermatogenesis and epididymis.

BMP8B BMP8A

7.09e-06354211784057
Pubmed

Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a.

BMP8B BMP8A

7.09e-06354225451979
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NID2 CACTIN FAT1 MAPT ZC3H4 RCN1 RCN2 BAZ1B P3H4 AGTPBP1

7.37e-061116541031753913
Pubmed

Characterization and chromosomal localization of PTPRO, a novel receptor protein tyrosine phosphatase, expressed in hematopoietic stem cells.

BMP8B BMP8A

1.42e-0545429434160
Pubmed

Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development.

BMP8B BMP8A

1.42e-0545428843393
Pubmed

Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.

WNK3 WNK2

1.42e-05454234384519
Pubmed

Common variants at 12q15 and 12q24 are associated with infant head circumference.

SBNO1 MAPT

1.42e-05454222504419
Pubmed

Analysis of BCL-6, CD95, PIM1, RHO/TTF and PAX5 mutations in splenic and nodal marginal zone B-cell lymphomas suggests a particular B-cell origin.

PIM1 BCL6

1.42e-05454217476282
Pubmed

WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.

WNK3 WNK2

1.42e-05454211571656
Pubmed

Human hypertension caused by mutations in WNK kinases.

WNK3 WNK2

1.42e-05454211498583
Pubmed

The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors.

USP5 OTULIN

2.36e-05554226235645
Pubmed

Differential HDAC1 and 2 Recruitment by Members of the MIER Family.

MIER3 MIER1

2.36e-05554228046085
Pubmed

Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation.

BMP8B BMP8A

3.54e-0565429878243
Pubmed

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development.

BMP8B BMP8A

3.54e-0565427605753
Pubmed

A General in Vitro Assay for Studying Enzymatic Activities of the Ubiquitin System.

USP5 MAPT

3.54e-05654231951392
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

MDN1 CPSF6 G3BP2 BAZ1B RIOK2

4.46e-0525154528077445
Pubmed

Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.

WNK3 WNK2

4.94e-05754220525693
Pubmed

The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4.

BMP8B BMP8A

4.94e-0575429070944
Pubmed

Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat.

BMP8B BMP8A

4.94e-05754212107726
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ADCY4 HSP90B1 MDN1 SBNO1 CPSF6 PIM1 G3BP2 RCN2 BAZ1B BUB3

5.96e-051425541030948266
Pubmed

KLHL2 interacts with and ubiquitinates WNK kinases.

WNK3 WNK2

6.59e-05854223838290
Pubmed

The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.

WNK3 WNK2

6.59e-05854223387299
Pubmed

Gene structure and evolution of testicular haploid germ cell-specific genes, Oxct2a and Oxct2b.

BMP8B BMP8A

8.46e-05954215028287
Pubmed

Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis.

BMP8B BMP8A

8.46e-0595421460021
Pubmed

The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers.

MGAM MYO5C

8.46e-05954225857663
Pubmed

Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.

BMP8B BMP8A

1.29e-041154210721728
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

MAGEA1 HSP90B1 MDN1 ZC3H4 CPSF6 RCN1 BAZ1B BUB3

1.36e-0498954836424410
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

USP5 FAT1 MDN1 EFS

1.44e-0417054423314748
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

MAGEA1 HSP90B1 FAT1 CTSC RCN1 RCN2 BUB3 RIOK2 P3H4

1.59e-04129754933545068
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

USP5 HSP90B1 CPSF6 G3BP2 BAZ1B BUB3 TEF

1.60e-0475454735906200
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

FAT1 CEBPD ZC3H4 BAZ1B BMP8A

1.66e-0433254537433992
Pubmed

Bmp7 regulates germ cell proliferation in mouse fetal gonads.

BMP8B BMP8A

1.83e-041354218391523
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

USP5 HSP90B1 MDN1 CPSF6 CTSC

1.95e-0434454530333137
Pubmed

New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.

BMP8B BMP8A

2.13e-041454211526197
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

MDN1 ZC3H4 CTSC BUB3 MIER1

2.50e-0436354514691545
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

NPHS1 HSP90B1 EFS PIM1 CLEC7A BMP8A BCL6

2.75e-0482454720237496
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

HSP90B1 MDN1 OTULIN CPSF6 G3BP2 BUB3

2.80e-0458254620467437
Pubmed

Global comparative transcriptome analysis of cartilage formation in vivo.

BMP8B BMP8A

2.80e-041654219272164
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

USP5 HSP90B1 SBNO1 ZC3H4 CPSF6 G3BP2 RCN1 BUB3 RIOK2

3.03e-04141554928515276
Pubmed

Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.

BMP8B BMP8A

3.17e-041754214736746
Pubmed

Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.

HSP90B1 CTSC

3.17e-041754221795745
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

HSP90B1 MDN1 ZC3H4 G3BP2 RCN1 BAZ1B BUB3

3.24e-0484754735850772
Pubmed

Dysfunction of programmed embryo senescence is linked to genetic developmental defects.

BMP8B BMP8A

3.56e-041854237017267
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

NID2 HSP90B1 FAT1 CPSF6 CTSC RCN2 MIER1 P3H4 LCLAT1

3.65e-04145154930550785
Pubmed

PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.

HSP90B1 MDN1 RCN1 BUB3

3.65e-0421754431685992
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

USP5 HSP90B1 MDN1 ZC3H4 CPSF6 G3BP2 RCN1 RCN2

3.74e-04114954835446349
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

NID2 MDN1 CPSF6 RCN2

3.78e-0421954431353912
Pubmed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

HSP90B1 FAT1 RCN1 RCN2 BUB3

3.95e-0440154525852190
Pubmed

Risk of non-Hodgkin lymphoma associated with germline variation in genes that regulate the cell cycle, apoptosis, and lymphocyte development.

PIM1 BCL6

4.42e-042054219336552
Pubmed

Neonatal Respiratory Failure with Retarded Perinatal Lung Maturation in Mice Caused by Reticulocalbin 3 Disruption.

RCN1 RCN2

4.42e-042054226252542
Pubmed

Regulation of the endosomal SNX27-retromer by OTULIN.

USP5 OTULIN

4.88e-042154231541095
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

USP5 HSP90B1 FAT1 CTSC RCN1 RCN2 NCAPH2 P3H4

5.01e-04120154835696571
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZNF317 MIER1 WNK3

5.29e-0410154310997877
Pubmed

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.

PIM1 BCL6

5.36e-042254228334989
Pubmed

Mapping wild-type and R345W fibulin-3 intracellular interactomes.

HSP90B1 RCN1

5.36e-042254227777122
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

CACTIN USP5 FAT1 ZC3H4 CTSC NDST2 BCL6 AGTPBP1

5.41e-04121554815146197
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

ZC3H4 CPSF6 BAZ1B BUB3

6.31e-0425154431076518
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

CACTIN HSP90B1 CPSF6 G3BP2 BUB3 RIOK2 MYO5C

6.39e-0494954736574265
Pubmed

Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.

BMP8B CLEC7A BMP8A

6.44e-0410854331202927
Pubmed

Global landscape of HIV-human protein complexes.

HSP90B1 LIMD1 G3BP2 RCN1 RCN2

7.14e-0445754522190034
Pubmed

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.

HSP90B1 CPSF6 CTSC G3BP2 RCN2

7.57e-0446354534901782
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

HSP90B1 OTULIN RCN1 RCN2 LCLAT1

7.94e-0446854531056421
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

CACTIN CRYBG2 ZC3H4 CPSF6 BUB3

8.02e-0446954527634302
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

MAGEA1 HSP90B1 CPSF6 G3BP2 RCN1 RCN2

8.20e-0471454628302793
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

LIMD1 MAPT ZC3H4 G3BP2 BUB3 AGTPBP1

8.81e-0472454636232890
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

HSP90B1 MDN1 CPSF6 G3BP2 RCN2 BUB3

8.87e-0472554627025967
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

ZC3H4 CPSF6 G3BP2 RCN2 BUB3

9.40e-0448654530940648
Pubmed

Phosphorylated tau interactome in the human Alzheimer's disease brain.

USP5 HSP90B1 MAPT

9.83e-0412554332812023
Pubmed

Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.

HSP90B1 RCN2 MYO5C

9.83e-0412554336030824
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

CACTIN ZC3H4 CPSF6 BAZ1B

9.86e-0428354430585729
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

HSP90B1 MDN1 ZC3H4 CPSF6 RCN1 BAZ1B MYO5C

9.96e-04102454724711643
Pubmed

SARS-CoV-2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets.

HSP90B1 G3BP2

1.00e-033054234780058
Pubmed

Hepatic lipase maturation: a partial proteome of interacting factors.

HSP90B1 RCN1

1.07e-033154219136429
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CACTIN CPSF6 CTSC G3BP2 RCN2 BUB3 RIOK2 AGTPBP1

1.18e-03137154836244648
Pubmed

Forkhead box a2 (FOXA2) is essential for uterine function and fertility.

BMP8B BMP8A

1.21e-033354228049832
Pubmed

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis.

BMP8B BMP8A

1.21e-033354232640236
Pubmed

In silico prediction of physical protein interactions and characterization of interactome orphans.

MAPT PIM1 BCL6

1.25e-0313654325402006
Pubmed

Proteomic analysis of the NOS2 interactome in human airway epithelial cells.

FAT1 RCN1 RCN2

1.31e-0313854323438482
Pubmed

[IMAGE: molecular integration of the analysis of the human genome and its expression].

BMP8B WNK3

1.36e-03355427757816
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

FAT1 CPSF6 RCN1 RCN2 P3H4

1.41e-0353354525544563
Pubmed

Analysis of phosphatase and tensin homolog tumor suppressor interacting proteins by in vitro and in silico proteomics.

G3BP2 P3H4

1.44e-033654215717329
Pubmed

Human transcription factor protein interaction networks.

FAT1 LIMD1 G3BP2 RCN1 RCN2 BAZ1B MIER1 MYO5C

1.54e-03142954835140242
InteractionEP300 interactions

USP5 CEBPD SBNO1 MAPT ZC3H4 CPSF6 G3BP2 RCN1 RCN2 BAZ1B BCL6 BUB3 MN1 MIER1

1.34e-0514015414int:EP300
InteractionTMEM106B interactions

HSP90B1 FAT1 CTSC RCN1 RCN2 BUB3 P3H4

1.78e-05309547int:TMEM106B
InteractionTAFAZZIN interactions

NID2 BMP8B FAT1 NDST2 BMP8A P3H4

1.87e-05207546int:TAFAZZIN
GeneFamilyBone morphogenetic proteins|Astacins

BMP8B BMP8A

2.10e-0411362455
GeneFamilyC-type lectin domain family

CLEC7A CLEC16A

3.94e-0347362494
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MIER3 MIER1

4.98e-0353362532
ToppCelldistal-3-Hematologic-Plasma|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSP90B1 BMP8B PIM1 TENT5C PAIP2B

3.77e-06194545d6e2e17732ad75604525fd65b2a3171e86cd01c7
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|390C / Donor, Lineage, Cell class and subclass (all cells)

MGAM BMP8B PIM1 G3BP2

2.73e-0514354410473c0f030d5ff760263042dc4b584787cb4a7f
ToppCellInfluenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class

MGAM BCL6 WNK2 MYO5C

4.35e-0516154498c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

CEBPD MAPT PREX2 LCLAT1

4.56e-05163544f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellICU-SEP-Lymphocyte-B-Plasmablast|ICU-SEP / Disease, Lineage and Cell Type

BMP8B TENT5C BMP8A WNK2

4.89e-0516654498ce43e14133418f676f1c88c001add9e28259a7
ToppCellInfluenza_Severe-Neutrophil|World / Disease group and Cell class

MGAM CEBPD BCL6 WNK2

5.25e-051695446e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCellsevere_influenza-Neutrophil|World / disease group, cell group and cell class (v2)

MGAM CEBPD BCL6 WNK2

5.88e-05174544f9f07436b7d3f190800cd85d229f007032f391e1
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HSP90B1 BMP8B TENT5C PAIP2B

6.85e-05181544f7b08f662eb77ee7a777c6525ddc3195046aaf65
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT1 EFS RCN1 BMP8A

7.00e-05182544193cb2df3d7ea4cb9a11390b92955e7d9b0a053a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM CEBPD CLEC7A BCL6

7.15e-05183544340621a8e720bd98da335f90598096833681834c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM CEBPD CLEC7A BCL6

7.15e-0518354475da8c05b6d636f434c5684e0166fed0de3547b4
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

HSP90B1 BMP8B TENT5C BMP8A

7.61e-05186544e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MGAM CEBPD CLEC7A BCL6

7.77e-0518754475bc05a0ba2727fecc236903ace792a28f3d3c9a
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MGAM CEBPD CLEC7A BCL6

7.77e-05187544a0d59bf1043ff5a1e8110b39ecc2d3932675edd4
ToppCellcontrol-Myeloid-Neutrophils_4|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

7.93e-0518854422d76c222fb0e3da08e10191af0090f14e03f2ad
ToppCellhealthy_donor-Lymphocytic-Plasma_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

HSP90B1 BMP8B TENT5C BMP8A

7.93e-05188544bd53b0371154cff680226897b61c9809a239d1b6
ToppCellCOVID-19_Severe-Myeloid_G-Neutrophil|COVID-19_Severe / Disease group, lineage and cell class

MGAM CEBPD CLEC7A BCL6

8.10e-05189544a62f4c445ede00d15b74bee65f4e4fb54cfd4d32
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MGAM CEBPD CLEC7A BCL6

8.10e-05189544f6b2b4824505f0119a017fdb73c55418fb651645
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MGAM CEBPD CLEC7A BCL6

8.10e-05189544db8e314ce95c32542bb4015a77032a33211fea0b
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSP90B1 EFS RCN1 MN1

8.26e-05190544947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSP90B1 EFS RCN1 MN1

8.43e-05191544db4943dd19207663fb9e27f8940fa4b06a933625
ToppCellmetastatic_Brain-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

CTSC CLEC7A TENT5C MYO5C

8.60e-051925447c6f44716fc684b0297f266f04968e26fabdf6e3
ToppCellmild-Lymphocytic-CD4_T_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

8.60e-051925444cd8f572e067bf5fe22f62fa868d7d332f097a8c
ToppCellCOPD-Myeloid-ncMonocyte|COPD / Disease state, Lineage and Cell class

CEBPD LIMD1 CLEC7A AGTPBP1

8.78e-05193544936ca95995599356b794fba32bfd82d8de339365
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MGAM CEBPD CLEC7A BCL6

8.95e-05194544e2d0dfb92356fa7ad7008aa8ac4198e2ac5d2495
ToppCellcontrol-Lymphocytic-CD4_T_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

8.95e-05194544c2ae2ea848d78725455dcb6be9f1d8933745fa80
ToppCellCOVID_vent-Myeloid-Monocytic-Neutrophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

MGAM CEBPD CLEC7A BCL6

8.95e-05194544eb23b171e429165dd26a64377eae7fa2ce25f547
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NPHS1 RCN1 WNK3 WNK2

8.95e-051945442dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPHS1 NID2 FAT1 CTSC

8.95e-051945441374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellmild-Myeloid-Neutrophils_3|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

9.13e-05195544a1cfed0092debcc003eff6a62508556b7664d5e1
ToppCelldistal-Hematologic-Plasma-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BMP8B PIM1 TENT5C PAIP2B

9.13e-051955444280a5bc5ed9bb12e278b182e0be6cb88fa83d83
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT1 LIMD1 TENT5C WNK2

9.13e-05195544dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FAT1 CEBPD CTSC

9.32e-0519654434e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCelldistal-Hematologic-Plasma-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSP90B1 PIM1 TENT5C PAIP2B

9.32e-051965448201aded3c7109fae5e6ca12bac2076acc7bf070
ToppCellproximal-3-Hematologic-Plasma|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSP90B1 BMP8B TENT5C PAIP2B

9.32e-051965441ca453582b5db8f1ea20a846e698c54edf0a1f25
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 FAT1 CEBPD CTSC

9.32e-051965448f82e01ca50aa4cd6149547505b4474a02fad618
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MGAM CEBPD CLEC7A BCL6

9.32e-05196544ad193b231ff2f7c72590fab79919c179d5d2f327
ToppCellproximal-Hematologic-Plasma-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSP90B1 BMP8B TENT5C PAIP2B

9.32e-05196544f6e842b18765c2d923706cabb5d17efeff1da5aa
ToppCellcontrol-Others-Megakaryocytes|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

9.32e-0519654410d914f1612622f64ac71da04e1995a854a4bec9
ToppCelldistal-Hematologic-Plasma|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BMP8B PIM1 TENT5C PAIP2B

9.32e-051965442a11dc1e51c64af7705e1622a9da583a6634c563
ToppCellproximal-Hematologic-Plasma|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSP90B1 BMP8B TENT5C PAIP2B

9.32e-05196544621f112a71f3d82fd75da8addfb16d86f590fe33
ToppCellmild-Myeloid-Neutrophils_4|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

9.32e-05196544f8c98cded5550843322b1711e1a57c7e88cae861
ToppCellmild-Myeloid-Neutrophils_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

9.32e-05196544e9f30eb8a3915c3b2af009c832bff9b349b65ae5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPHS1 NID2 FAT1 CTSC

9.32e-05196544545d2e4469924d333e3f655f559c899fa1260196
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

FAT1 CTSC BCL6 MYO5C

9.50e-0519754444a59dfb889577b3160a5b13ada1276771a00241
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.50e-051975442ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RCN1 TENT5C WNK2 MYO5C

9.50e-05197544d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellsevere-Lymphocytic-CD4_T_cells_2|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

9.50e-051975443b71e523d8a68f131def17233385df371db70db5
ToppCell10x_3'_v3-blood_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MGAM CEBPD CLEC7A AGTPBP1

9.50e-051975442d3547107c88c7443fc6425742694e13368a71f5
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RCN1 TENT5C WNK2 MYO5C

9.50e-0519754480b05c8ad9c1edc5dea3236079372475431343fe
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.50e-0519754463b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.50e-05197544fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCellsevere-Others-Megakaryocytes|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAM CEBPD CLEC7A BCL6

9.50e-05197544fc0864e2de2d9f99084586b467551b6da535d933
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.69e-051985441f956e369e00d37835095a001db4b62a79014532
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.69e-05198544dc6fbad0ecdd057189f71afcdb6aca25207314a3
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NPHS1 RCN1 WNK3 WNK2

9.69e-05198544dd0465b45b02cb8edf0914d19afb52fcaaeb012c
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MGAM CEBPD BCL6 AGTPBP1

9.69e-05198544df546a9afc0e15398f33c1b511c7281771f9aea0
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.69e-051985446a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.88e-05199544d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.88e-051995447b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MGAM CEBPD CLEC7A BCL6

9.88e-051995440dde17381b8a95bfddb4d1052b13d33f37b05d13
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.88e-05199544f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCellASK454-Immune-B_cell|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CEBPD CTSC CLEC7A BCL6

9.88e-05199544b9b0ae81b9e7e35023c73d3b936e88167461ba54
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT1 RCN1 BMP8A P3H4

9.88e-05199544bf138cc692df727e087d140c014149ee5da00d9d
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6_(Thalamus,_glutamatergic)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MGAM GRID2IP MYO5C

9.97e-0574543ef4c9eafc794c7d50aef28b37d21b52d3c511499
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6_(Thalamus,_glutamatergic)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MGAM GRID2IP MYO5C

9.97e-05745436ecbdf4186039a031410e09ecd5afa66b6d5e2dc
ToppCell390C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

HSP90B1 CEBPD CTSC RCN1

1.01e-04200544019340e8b4b4944a49e14fdec7ce2954cbb8ba2e
ToppCellsevere-Neutrophil|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MGAM CEBPD CLEC7A BCL6

1.01e-04200544f9af7e77a8483ab4ae708b55514e64f5420fa0c1
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 BCL6 MN1 PREX2

1.01e-04200544862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 BCL6 MN1 PREX2

1.01e-04200544a91345f268f13170c27309333603eb82400c9947
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT1 EFS BMP8A P3H4

1.01e-042005443c898e81444b001835c3f1bbc68183078701b135
ToppCell390C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

HSP90B1 CEBPD CTSC RCN1

1.01e-04200544b6f21f5cc137eddf6ba90e81cae791b57d88d9d7
ToppCellsevere-Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MGAM CEBPD CLEC7A BCL6

1.01e-04200544f04d5951bac4dee47c22aaf7973312ca797f322e
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT1 EFS BMP8A P3H4

1.01e-042005443eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellCOVID-19-COVID-19_Severe-Myeloid-Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

MGAM CEBPD CLEC7A BCL6

1.01e-04200544fec2660c9a9977b3b3a2eaed063b9049c0b07ff2
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT1 BCL6 MN1 PREX2

1.01e-04200544d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellmild-Others-Megakaryocytes|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CEBPD CLEC7A BCL6

2.09e-049554374df0149882e2cd0d9aba0ef1ae4aac2cc1aeeac
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NPHS1 MDN1 CLEC16A

5.73e-0413454364979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM CLEC7A BCL6

6.65e-041415439f26b2a5ccdf8762f16b673e59543b694fbacc10
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM CLEC7A BCL6

6.93e-041435435d5ba2717126a0d4e4464f3604cb282cb977d5b2
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HSP90B1 BMP8B TENT5C

7.21e-04145543fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellfacs-Aorta-Heart-24m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTULIN CLEC7A TENT5C

8.26e-04152543525d65c5c8e5580947367afdb1f6e68b49e9e5bb
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIM1 CLEC7A BCL6

8.42e-041535438cc2667213bfac37545bb63181e88ef1f1834413
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIM1 CLEC7A BCL6

8.42e-04153543596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPHS1 NID2 FAT1

8.91e-04156543dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPHS1 NID2 FAT1

8.91e-04156543abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellfacs-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM CEBPD CLEC7A

8.91e-04156543f532ef4e92ac7661b1a8a4f2e98d80ce8d4e3655
ToppCellfacs-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM CEBPD CLEC7A

8.91e-04156543da4f35353a84d919e683554932f110e29568df33
ToppCellfacs-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM CEBPD CLEC7A

8.91e-04156543f1e25ff85c5f2f8555f9fb5ae5daed7ddb418fd1
ToppCell343B-Lymphocytic-Plasma_cell-|343B / Donor, Lineage, Cell class and subclass (all cells)

HSP90B1 TENT5C PAIP2B

9.07e-04157543554ddbaf83f5d6eb4669c673efdbb28fd87e2ba8
ToppCell343B-Lymphocytic-Plasma_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

HSP90B1 TENT5C PAIP2B

9.07e-041575432cb3deb5313ce734710c601935ca318e4179077e
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACTIN AGTPBP1 MYO5C

9.24e-041585432ae863ccef201414b82a2ecf7cf1bbb1b0ce4a3c
ToppCellfacs-Aorta-Heart-24m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTULIN PIM1 TENT5C

9.41e-04159543443f6df4a88fa8755adcde4cc12575dff614ecb4
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

HSP90B1 TENT5C PAIP2B

9.41e-04159543204e5a675f4684c9570c24c8d34bbf632fd8164a
ToppCell367C-Lymphocytic-ILC|367C / Donor, Lineage, Cell class and subclass (all cells)

NPHS1 G3BP2 TENT5C

9.58e-04160543f70ec054b6d51c1565e4a257cbe3c9537c0eb09f
ToppCellLAM-Lymphoid-B-cell-2|LAM / Condition, Lineage and Cell class

HSP90B1 TENT5C PAIP2B

9.58e-041605430060c2b3304f411c682aa2ba20bcf80f346d2403
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LIMD1 BMP8A PREX2

9.76e-04161543b19f82dd98a3064581793711bb70373f18abecd9
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

ADCY4 MDN1 PREX2

9.76e-041615431973b112d8d67aacc02751797d0148e7b53bfa66
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CEBPD CTSC CLEC7A

1.01e-03163543a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCelldroplet-Fat-Gat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM PIM1 CLEC7A

1.03e-03164543c7ad946829c655038b33748dddd7d68c15489034
DrugCP-863187 [668981-07-5]; Down 200; 10uM; PC3; HT_HG-U133A

NPHS1 CRYBG2 LIMD1 G3BP2 CDADC1 PAIP2B

6.51e-061945467558_DN
DrugDiltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; HL60; HG-U133A

SBNO1 CPSF6 RCN2 BUB3 RIOK2 AGTPBP1

7.53e-061995462032_DN
Drugcallyspongynic acid

MGAM GANC

1.65e-053542CID000636783
DrugIPG7F

MGAM GANC

1.65e-053542CID003083273
DrugPradimicin Q

MGAM GANC

1.65e-053542CID000073572
Drug7-deoxy-6-epi-castanospermine

MGAM GANC

1.65e-053542CID000125391
DrugAC1NUR2V

MGAM GANC

1.65e-053542CID005489114
Drug3-nitro-4-(6-aminohexylamido)phenylboronic acid

MGAM GANC

1.65e-053542CID000133488
Drugmyrciaphenone B

MGAM GANC

3.30e-054542CID000183139
Drugglycovir

MGAM GANC

3.30e-054542CID000060807
Drugthiochroman-4-one

MGAM GANC

3.30e-054542CID000019048
Drug2-deoxymaltose

MGAM GANC

3.30e-054542CID003081508
DrugAC1L3RZ0

MGAM GANC

3.30e-054542CID000145814
DrugNSC277293

MGAM GANC

3.30e-054542CID000321973
Druggamma-glutamyl-2-naphthylamide

MGAM GANC

3.30e-054542CID000164706
Drugatalaphyllidine

MGAM GANC

3.30e-054542CID005479542
DrugThiram

USP5 FAT1 CEBPD SBNO1 CPSF6 PIM1 CTSC TENT5C

3.45e-05533548ctd:D013893
Drugtetrachlorophthalimide

MGAM GANC

5.50e-055542CID000074077
DrugPCB 167

MGAM TEF

5.50e-055542CID000040479
Drug(-)-Lentiginosine

MGAM GANC

5.50e-055542CID000130407
DrugD-gluco-octenitol

MGAM GANC

5.50e-055542CID006438548
Drugbeta-D-glucopyranosyl azide

MGAM GANC

5.50e-055542CID000152302
Drugpulmatin

MGAM GANC

5.50e-055542CID000442731
DrugRo 22-0654

MGAM GANC

5.50e-055542CID000133753
Drugsodium amide

MGAM RCN1

5.50e-055542CID000024533
DrugAC1L1IZ2

MGAM ADCY4 HSP90B1 PIM1 RIOK2 MYO5C

8.13e-05304546CID000004795
DrugAC1OCFTL

MGAM GANC

8.23e-056542CID006918743
Drugconduritol aziridine

MGAM GANC

8.23e-056542CID000130051
DrugAC1NSXES

MGAM GANC

8.23e-056542CID005318890
DrugBAS 012416453; Down 200; 38uM; PC3; HT_HG-U133A

PIM1 BAZ1B PAIP2B NCAPH2 P3H4

9.61e-051945456876_DN
DrugLY 294002; Up 200; 10uM; PC3; HT_HG-U133A

MAPT PIM1 PAIP2B NCAPH2 BCL6

9.61e-051945451239_UP
DrugAmprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

PIM1 CDADC1 TENT5C PAIP2B NCAPH2

1.01e-041965451479_UP
DrugOxybenzone [131-57-7]; Down 200; 17.6uM; PC3; HT_HG-U133A

NID2 CACTIN MAPT CDADC1 NCAPH2

1.01e-041965456309_DN
Drugrosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A

CACTIN CRYBG2 PIM1 BAZ1B NCAPH2

1.01e-041965451658_UP
DrugChenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A

CACTIN NDST2 CDADC1 TENT5C NCAPH2

1.03e-041975456012_DN
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A

CACTIN CRYBG2 EFS CDADC1 TEF

1.03e-041975456497_UP
DrugDimenhydrinate [523-87-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A

EFS MAPT CDADC1 PAIP2B NCAPH2

1.03e-041975455450_UP
DrugChicago sky blue 6B [2610-05-1]; Up 200; 4uM; HL60; HT_HG-U133A

CACTIN USP5 CRYBG2 NCAPH2 BCL6

1.06e-041985451330_UP
DrugGramine [87-52-5]; Down 200; 23uM; MCF7; HT_HG-U133A

PIM1 BAZ1B PAIP2B NCAPH2 P3H4

1.06e-041985452799_DN
Drugvinblastine sulfate; Down 200; 0.1uM; PC3; HT_HG-U133A

NPHS1 CACTIN CRYBG2 LIMD1 CDADC1

1.06e-041985457556_DN
DrugMecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A

USP5 PIM1 NDST2 NCAPH2 PREX2

1.06e-041985457023_UP
DrugFurazolidone [67-45-8]; Up 200; 17.8uM; MCF7; HT_HG-U133A

PIM1 CLEC7A BMP8A BCL6 TEF

1.08e-041995453358_UP
DrugGlutethimide, para-amino [125-84-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A

CACTIN MAPT BAZ1B NCAPH2 CLEC16A

1.08e-041995457421_DN
DrugPHA-00816795 [212631-79-3]; Down 200; 10uM; PC3; HT_HG-U133A

NID2 USP5 HSP90B1 G3BP2 NCAPH2

1.08e-041995457072_DN
DrugDiperodon hydrochloride [537-12-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A

CACTIN MAPT PIM1 TENT5C NCAPH2

1.08e-041995456836_DN
Drug3KBG5CNP

MGAM GANC

1.15e-047542CID003083250
Drugmyrciacitrin I

MGAM GANC

1.15e-047542CID000183137
DrugMor-502

MGAM GANC

1.15e-047542CID003080955
DrugND2001

MGAM GANC

1.15e-047542CID000160207
DrugN-dodecylimidazole

MGAM GANC

1.15e-047542CID000078002
Drugheptenitol

MGAM GANC

1.15e-047542CID000188267
DrugVAL-TRP

MGAM GANC

1.15e-047542CID000168182
Drugisomaltotetraose

MGAM GANC

1.15e-047542CID003080783
Drugdesmanthin-1

MGAM GANC

1.15e-047542CID005316590
Drugcisapride

ADCY4 FAT1 CEBPD MAPT

1.45e-04112544CID000002769
Drugindeloxazine

MGAM GANC

1.53e-048542CID000003704
Drug9 mM of H

MGAM GANC

1.53e-048542CID000130464
Drug3,4,5-triCQA

MGAM GANC

1.53e-048542CID006440783
DrugNSC636590

MGAM GANC

1.53e-048542CID000072285
DrugAC1L6VJ8

MGAM GANC

1.53e-048542CID000300088
Drugcasuarictin

MGAM GANC

1.53e-048542CID000073644
DrugAC1NSUE6

MGAM GANC

1.53e-048542CID005316558
DrugN-dodecyl morpholine

MGAM GANC

1.53e-048542CID000073764
Drugpotassium bromide

MGAM HSP90B1 CTSC

1.78e-0446543CID000253877
Drugleucrose

MGAM GANC

1.97e-049542CID000165577
Drugm265

MGAM GANC

1.97e-049542CID000074189
Drugnectrisine

MGAM GANC

2.45e-0410542CID000122106
DrugAC1LCY75

MGAM GANC

2.45e-0410542CID000639298
Drug( )-Calystegine A3

MGAM GANC

2.45e-0410542CID000183073
DrugGlc)4

MGAM GANC

2.45e-0410542CID000189098
DrugRo 20-0083

MGAM GANC

2.45e-0410542CID003082332
DrugAC1L3M0Q

MGAM GANC

2.45e-0410542CID000118008
DrugTAK-013

MGAM GANC

2.45e-0410542CID003038517
Drugdesoxyrhaponticin

MGAM GANC

2.45e-0410542CID004430533
Drugtrehazolin

MGAM GANC

2.45e-0410542CID003081797
Drugmeso-erythritol

MGAM GANC MIER1

2.87e-0454543CID000008998
Drugglucosyl fluoride

MGAM GANC

3.00e-0411542CID000150967
DrugDDMU

CTSC TEF

3.00e-0411542CID000098491
DrugCNP-G5

MGAM GANC

3.00e-0411542CID000127309
Druggalactosylarabinose

MGAM GANC

3.00e-0411542CID000193417
Drugtrehalulose

MGAM GANC

3.00e-0411542CID000162104
DrugAC1NUSO2

MGAM GANC

3.00e-0411542CID005460006
Drugnicotinoylprocaine

MGAM GANC

3.59e-0412542CID000159667
DrugAC1LCT6N

MGAM GANC

3.59e-0412542CID000606283
Drugscutellarein

MGAM GANC

3.59e-0412542CID005281697
Drugcolestimide

MGAM GANC

4.24e-0413542CID000065840
DrugMDL 25,637

MGAM GANC

4.24e-0413542CID000128548
Drugvaliolamine

MGAM GANC

4.24e-0413542CID000174312
Drugcast 3

MGAM GANC

4.24e-0413542CID000072360
Drugmaltal

MGAM GANC

4.24e-0413542CID000169427
Drugmethyl 1'-epiacarviosin

MGAM GANC

4.24e-0413542CID000197426
Drugisoacarbose

MGAM GANC

4.24e-0413542CID000449165
Druggalloylglucose

MGAM GANC

4.24e-0413542CID000124375
DrugNSC77009

MGAM GANC

4.24e-0413542CID000253775
Drugmannostatin A

MGAM GANC

4.24e-0413542CID000124189
Diseasepseudohypoaldosteronism (implicated_via_orthology)

WNK3 WNK2

4.73e-056532DOID:4479 (implicated_via_orthology)
Diseasenephrotic syndrome

NPHS1 BCL6 CLEC16A

2.87e-0471533EFO_0004255
Diseaseglucose homeostasis measurement, glucose effectiveness measurement

BCL6 MYO5C

3.27e-0415532EFO_0006833, EFO_0006896
Diseaseosteoarthritis

GRID2IP SBNO1 MAPT CPSF6

6.84e-04222534MONDO_0005178
Diseaseneutrophil percentage of leukocytes

CEBPD SBNO1 MAPT BCL6 TEF CLEC16A

7.67e-04610536EFO_0007990
Diseasenephrotic syndrome (implicated_via_orthology)

NPHS1 FAT1

8.52e-0424532DOID:1184 (implicated_via_orthology)
Diseasebasophil percentage of leukocytes

CEBPD GANC CTSC BCL6

9.57e-04243534EFO_0007992
Diseasediabetes mellitus (implicated_via_orthology)

BMP8B BMP8A

1.00e-0326532DOID:9351 (implicated_via_orthology)
Diseasecortex volume change measurement, age at assessment

CTSC WNK2

1.16e-0328532EFO_0008007, EFO_0021500
Diseaseallergic disease

SBNO1 BCL6 TEF CLEC16A

1.19e-03258534MONDO_0005271
Diseaseasthma, Eczema, allergic rhinitis

OTULIN TEF CLEC16A

1.36e-03121533EFO_0005854, HP_0000964, MONDO_0004979
DiseaseCCL2 measurement

LIMD1 ZC3H4 CLEC16A

1.52e-03126533EFO_0004749
Diseaseallergic rhinitis

BCL6 CLEC16A MIER1

1.78e-03133533EFO_0005854
DiseaseCOVID-19 symptoms measurement

LIMD1 MAPT

1.81e-0335532EFO_0600019
Diseasemonocyte count

CRYBG2 CEBPD CTSC TENT5C BCL6 MN1 MIER1 PREX2

2.32e-031320538EFO_0005091
DiseaseEczema

BCL6 TEF CLEC16A LCLAT1

2.33e-03310534HP_0000964
Diseaseunipolar depression, age at onset

FAT1 PAIP2B

2.36e-0340532EFO_0003761, EFO_0004847
Diseasesubiculum volume

MAPT WNK2

2.73e-0343532EFO_0009399
Diseaseoverall survival, pancreatic carcinoma

PAIP2B PREX2

3.53e-0349532EFO_0000638, EFO_0002618
Diseaseneutrophil measurement

CTSC TENT5C BCL6

3.99e-03177533EFO_0803548
Diseaseurinary albumin to creatinine ratio

MGAM FAT1 CTSC

4.12e-03179533EFO_0007778
DiseaseIGFBP-3 measurement

CACTIN CLEC16A

4.27e-0354532EFO_0004626

Protein segments in the cluster

PeptideGeneStartEntry
DEAEDYYDVITHPMD

BAZ1B

1371

Q9UIG0
SYMYEMDDTEHPEDG

BUB3

296

O43684
AYAVEDAGMEHRDPY

ADCY4

421

Q8NFM4
VGSEYADFPHMDDKQ

CDADC1

371

Q9BWV3
MYEHLFPELVDDFQD

AGTPBP1

421

Q9UPW5
AFEHPEEVDYMTEFV

RCN2

176

Q14257
GFVDQDEYIADMFSH

RCN1

221

Q15293
DEYIADMFSHEENGP

RCN1

226

Q15293
LSGHDEKENPFAEYM

PAIP2B

21

Q9ULR5
YGGHEDFSKMIDEAE

RIMKLA

131

Q8IXN7
MSDYESGDDGHFEEV

FAT1

4561

Q14517
DEDMAFPGHLYDEVE

NPHS1

1166

O60500
MEDSAGEGATEFHDY

MDN1

4661

Q9NU22
MEVYDGREHSAYGEP

MAGEA1

221

P43355
LEREMDAHPKADYFG

LIMD1

456

Q9UGP4
PYDVQHADIDYMDER

MGAM

406

O43451
HFEDMIDYFCDIHEP

LCLAT1

181

Q6UWP7
VDAGFDEHDIPYDAM

GANC

381

Q8TET4
DFDPTAEMLVHDYDD

MIER3

21

Q7Z3K6
AFTHDMEVTFYPGEE

NID2

611

Q14112
SDDPMAYIHFTAEGE

HSP90B1

366

P14625
QCPAEHEEDMYRAAD

OTULIN

46

Q96BN8
LTPENDYEEMSFHDD

GRID2IP

701

A4D2P6
MADGVDHIDIYADVG

CPSF6

1

Q16630
GAAAPAMYDDESAID

CEBPD

46

P49716
VHNDMFRYEDEVFGD

G3BP2

126

Q9UN86
DPAVVLFEAMDFEGH

CRYBG2

1261

Q8N1P7
MGQLYEDSHEEDDFL

GABARAPL3

91

Q9BY60
YHAMAGDDDEDGAPA

BMP8A

81

Q7Z5Y6
HHGPMAVAFEVYDDF

CTSC

366

P53634
MEDDPAGHHNEYEGI

EFS

361

O43281
PEEARSDMHYSVAEG

BCL6

266

P41182
SAEDDDLAVEMHEPY

CACTIN

316

Q8WUQ7
LGDMFYDEDLADSLH

ETFBKMT

186

Q8IXQ9
YHAMAGDDDEDGAPA

BMP8B

81

P34820
EDEEEMGHAETYAEY

SBNO1

231

A3KN83
EFDPSADMLVHDFDD

MIER1

21

Q8N108
EGYEHMAESQGPESF

MN1

151

Q10571
LLYDMVCGDIPFEHD

PIM1

231

P11309
GESFHLEYMDLDEFL

TEF

91

Q10587
IGESMYGDFEEAFDH

TENT5C

211

Q5VWP2
MEYHPDLENLDEDGY

CLEC7A

1

Q9BXN2
DLGAADDFLEPEEYM

NCAPH2

431

Q6IBW4
FLDMVYHALDSPDDD

CLEC16A

481

Q2KHT3
EEEDFQPREEAMLYH

P3H4

346

Q92791
FYHTGTEEEDAGDDM

NDST2

361

P52849
QEFEVMEDHAGTYGL

MAPT

6

P10636
SYFHSDEMDSGDELP

PREX2

1131

Q70Z35
HVEDPASVYDEAMEL

RIOK2

201

Q9BVS4
GSMGGDHPEDEEDFY

ZC3H4

271

Q9UPT8
DGDAPDEIATYMVEH

WNK2

1221

Q9Y3S1
TEYAHLFEVFGMDPH

ZNF317

166

Q96PQ6
YDEDDMVLDPSLAEH

USP5

261

P45974
DVDGDAPEDIADYMV

WNK3

776

Q9BYP7
GDMDPHIFAVAEEAY

MYO5C

131

Q9NQX4