Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D3E TBC1D3 RASAL3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.59e-102796812GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D3E TBC1D3 RASAL3 TBC1D3H TBC1D3L TBC1D3D NGEF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.37e-085076813GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D3E TBC1D3 RASAL3 TBC1D3H TBC1D3L TBC1D3D NGEF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.37e-085076813GO:0030695
GeneOntologyMolecularFunctionenzyme activator activity

TBC1D3E TBC1D3 RASAL3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.93e-066566812GO:0008047
GeneOntologyMolecularFunctionmolecular function activator activity

TBC1D3E BMP8B TBC1D3 RASAL3 TBC1D3H TBC1D3L TBC1D3D BMP8A TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

5.78e-0512336814GO:0140677
GeneOntologyMolecularFunctionenzyme regulator activity

TBC1D3E TBC1D3 RASAL3 TBC1D3H TBC1D3L TBC1D3D NGEF DMPK TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.54e-0414186814GO:0030234
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NGEF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.75e-151096912GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NGEF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.78e-112446912GO:0043547
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3E TBC1D3 RASAL3 TBC1D3H TBC1D3L TBC1D3D NGEF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

7.41e-113356913GO:0043087
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NGEF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

8.88e-084996912GO:0051345
GeneOntologyBiologicalProcessregulation of hydrolase activity

TBC1D3E TBC1D3 RASAL3 TBC1D3H TBC1D3L TBC1D3D NGEF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

5.84e-068786913GO:0051336
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D NGEF TBC1D3I TBC1D3G TBC1D3C TBC1D3B EDNRA TBC1D3K TBC1D3F

3.11e-0510286913GO:0043085
HumanPhenoRecurrent lower respiratory tract infections

DNAAF3 POLE PEPD IL17RA DNAH9 EDNRA DNAH11

1.26e-05288167HP:0002783
HumanPhenoAbnormal paranasal sinus morphology

DNAAF3 IL17RA FUCA1 DNAH9 EDNRA DNAH11

1.41e-05189166HP:0000245
HumanPhenoAbnormal bronchus morphology

DNAAF3 POLE IL17RA DNAH9 EDNRA DNAH11

2.96e-05215166HP:0025426
HumanPhenoAbnormal sputum

DNAAF3 IL17RA DNAH9 EDNRA DNAH11

4.34e-05136165HP:0032016
HumanPhenoAbnormality of the bronchi

DNAAF3 POLE IL17RA DNAH9 EDNRA DNAH11

6.35e-05246166HP:0002109
HumanPhenoNasal polyposis

DNAAF3 DNAH9 EDNRA DNAH11

6.55e-0574164HP:0100582
HumanPhenoAbnormal respiratory epithelium morphology

DNAAF3 DNAH9 DNAH11

7.94e-0528163HP:0012253
HumanPhenoAbnormal respiratory motile cilium morphology

DNAAF3 DNAH9 DNAH11

7.94e-0528163HP:0005938
HumanPhenoAbnormal nasal mucosa morphology

DNAAF3 DNAH9 EDNRA DNAH11

8.89e-0580164HP:0000433
HumanPhenoSinusitis

DNAAF3 IL17RA DNAH9 EDNRA DNAH11

1.26e-04170165HP:0000246
HumanPhenoBronchiectasis

DNAAF3 POLE DNAH9 EDNRA DNAH11

1.45e-04175165HP:0002110
HumanPhenoAbnormal respiratory motile cilium physiology

DNAAF3 DNAH9 DNAH11

1.70e-0436163HP:0012261
HumanPhenoRecurrent respiratory infections

DNAAF3 POLE PEPD IL17RA FUCA1 DNAH9 EDNRA DNAH11

3.76e-04660168HP:0002205
HumanPhenoPeribronchovascular interstitial thickening

DNAAF3 DNAH9 DNAH11

4.29e-0449163HP:0025177
HumanPhenoPulmonary situs ambiguus

DNAAF3 DNAH9 DNAH11

4.29e-0449163HP:0011617
HumanPhenoAbnormal pulmonary situs morphology

DNAAF3 DNAH9 DNAH11

4.29e-0449163HP:0011615
HumanPhenoLithoptysis

DNAAF3 DNAH9 DNAH11

4.29e-0449163HP:0032543
HumanPhenoEctopic pregnancy

DNAAF3 DNAH9 DNAH11

4.29e-0449163HP:0031456
HumanPhenoAtrial situs ambiguous

DNAAF3 DNAH9 DNAH11

4.56e-0450163HP:0011539
HumanPhenoRecurrent bacterial infections

DNAAF3 IL17RA DNAH9 EDNRA DNAH11

4.71e-04225165HP:0002718
HumanPhenoRecurrent otitis media

DNAAF3 ADAT3 IL17RA DNAH9 DNAH11

4.91e-04227165HP:0000403
HumanPhenoAbnormal inferior vena cava morphology

DNAAF3 DNAH9 DNAH11

5.41e-0453163HP:0025576
HumanPhenoAbnormal atrial arrangement

DNAAF3 DNAH9 DNAH11

5.72e-0454163HP:0011535
HumanPhenoRecurrent upper respiratory tract infections

DNAAF3 POLE IL17RA DNAH9 DNAH11

5.98e-04237165HP:0002788
HumanPhenoAirway obstruction

DNAAF3 DNAH9 EDNRA DNAH11

7.09e-04137164HP:0006536
HumanPhenoAbnormal nasopharynx morphology

DNAAF3 POLE IL17RA DNAH9 DNAH11

7.51e-04249165HP:0001739
HumanPhenoNasal congestion

DNAAF3 DNAH9 DNAH11

7.80e-0460163HP:0001742
HumanPhenoRecurrent mycobacterial infections

DNAAF3 DNAH9 DNAH11

8.59e-0462163HP:0011274
HumanPhenoAbnormal pharynx morphology

DNAAF3 POLE IL17RA DNAH9 DNAH11

9.15e-04260165HP:0033151
HumanPhenoAbnormality of the middle ear

DNAAF3 TRMT10C ADAT3 MOGS SLC26A5 PEPD IL17RA TECTA DNAH9 EDNRA DNAH11

9.25e-0414461611HP:0000370
HumanPhenoWheezing

DNAAF3 DNAH9 DNAH11

9.43e-0464163HP:0030828
HumanPhenoAbsent outer dynein arms

DNAAF3 DNAH9

9.48e-0415162HP:0012256
HumanPhenoAbnormality of the liver

TRMT10C MOGS POLE PEPD IL17RA FUCA1 LCAT DMPK KDM1A EDNRA

1.02e-0312051610HP:0001392
HumanPhenoPolysplenia

DNAAF3 DNAH9 DNAH11

1.03e-0366163HP:0001748
HumanPhenoAbnormal tracheobronchial morphology

DNAAF3 POLE IL17RA DNAH9 EDNRA DNAH11

1.04e-03410166HP:0005607
HumanPhenoNeonatal respiratory distress

DNAAF3 DMPK DNAH9 DNAH11

1.10e-03154164HP:0002643
HumanPhenoRecurrent upper and lower respiratory tract infections

DNAAF3 DNAH9 DNAH11

1.13e-0368163HP:0002873
HumanPhenoRecurrent sinopulmonary infections

DNAAF3 DNAH9 DNAH11

1.13e-0368163HP:0005425
HumanPhenoProductive cough

DNAAF3 DNAH9 DNAH11

1.13e-0368163HP:0031245
HumanPhenoAbnormal endocrine physiology

ADAT3 MOGS POLE KDM1A

1.16e-03156164HP:0031072
HumanPhenoChronic sinusitis

DNAAF3 DNAH9 DNAH11

1.17e-0369163HP:0011109
HumanPhenoAbsent/shortened dynein arms

DNAAF3 DNAH9

1.22e-0317162HP:0200106
HumanPhenoCough

DNAAF3 IL17RA DNAH9 DNAH11

1.27e-03160164HP:0012735
HumanPhenoRespiratory tract infection

DNAAF3 POLE PEPD IL17RA FUCA1 DNAH9 EDNRA DNAH11

1.38e-03797168HP:0011947
HumanPhenoChronic rhinitis

DNAAF3 DNAH9 DNAH11

1.38e-0373163HP:0002257
HumanPhenoAbnormal spleen morphology

DNAAF3 MOGS PEPD FUCA1 LCAT DNAH9 DNAH11

1.52e-03613167HP:0025408
HumanPhenoDynein arm defect of respiratory motile cilia

DNAAF3 DNAH9

1.53e-0319162HP:0012255
HumanPhenoRecurrent infections

DNAAF3 ADAT3 POLE PEPD IL17RA FUCA1 DNAH9 EDNRA DNAH11

1.57e-031030169HP:0002719
MousePhenoabnormal systemic artery morphology

DNAAF3 PEPD POLDIP2 SSR2 LCAT HECTD1 EDNRA DNAH11

6.86e-06304478MP:0011655
MousePhenoabnormal aorta morphology

DNAAF3 PEPD POLDIP2 SSR2 HECTD1 EDNRA DNAH11

9.27e-06225477MP:0000272
MousePhenoventricular septal defect

XIRP2 PEPD SSR2 HECTD1 KDM1A EDNRA DNAH11

2.43e-05261477MP:0010402
MousePhenoepididymis epithelium degeneration

BMP8B BMP8A

3.31e-053472MP:0004934
MousePhenoabnormal thoracic aorta morphology

DNAAF3 SSR2 HECTD1 EDNRA DNAH11

8.34e-05134475MP:0010468
MousePhenoabnormal artery morphology

DNAAF3 PEPD POLDIP2 SSR2 LCAT HECTD1 EDNRA DNAH11

9.67e-05440478MP:0002191
MousePhenomuscular ventricular septal defect

XIRP2 SSR2 HECTD1 DNAH11

1.27e-0477474MP:0010420
MousePhenoabnormal interventricular septum morphology

XIRP2 PEPD SSR2 HECTD1 KDM1A EDNRA DNAH11

1.34e-04342477MP:0000281
MousePhenoabnormal interventricular septum muscular part morphology

XIRP2 SSR2 HECTD1 DNAH11

1.40e-0479474MP:0010498
MousePhenodecreased cochlear microphonics

SLC26A5 TECTA

1.65e-046472MP:0004414
MousePhenoepididymis degeneration

BMP8B BMP8A

2.30e-047472MP:0004935
MousePhenoperimembraneous ventricular septal defect

SSR2 HECTD1 KDM1A EDNRA

2.52e-0492474MP:0010418
MousePhenoabnormal interventricular septum membranous part morphology

SSR2 HECTD1 KDM1A EDNRA

2.63e-0493474MP:0008823
MousePhenoabnormal heart septum morphology

XIRP2 PEPD SSR2 HECTD1 KDM1A EDNRA DNAH11

2.90e-04388477MP:0006113
MousePhenoaorta hypoplasia

HECTD1 EDNRA

3.92e-049472MP:0010541
MousePhenoabdominal situs inversus

DNAAF3 DNAH11

3.92e-049472MP:0011249
MousePhenointerrupted aorta

SSR2 EDNRA DNAH11

4.00e-0443473MP:0010544
MousePhenoabnormal pulmonary valve morphology

SSR2 HECTD1 DNAH11

4.58e-0445473MP:0002748
DomainTBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.29e-15496710SM00164
DomainRabGAP-TBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

3.02e-15536710PF00566
DomainTBC_RABGAP

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

4.51e-15556710PS50086
DomainRab-GTPase-TBC_dom

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

4.51e-15556710IPR000195
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG DMPK

7.57e-054672IPR014930
DomainMyotonic_dystrophy_kinase_coil

CDC42BPG DMPK

7.57e-054672PD011252
DomainDMPK_coil

CDC42BPG DMPK

7.57e-054672PF08826
DomainPH-BEACH_dom

NBEAL1 WDFY4

3.50e-048672IPR023362
Domain-

NBEAL1 WDFY4

3.50e-0486722.30.29.40
DomainDHC_N1

DNAH9 DNAH11

3.50e-048672PF08385
DomainPH_BEACH

NBEAL1 WDFY4

3.50e-048672PS51783
DomainDynein_heavy_dom-1

DNAH9 DNAH11

3.50e-048672IPR013594
DomainBEACH_dom

NBEAL1 WDFY4

4.49e-049672IPR000409
DomainBEACH

NBEAL1 WDFY4

4.49e-049672PS50197
DomainBeach

NBEAL1 WDFY4

4.49e-049672PF02138
Domain-

NBEAL1 WDFY4

4.49e-0496721.10.1540.10
DomainBeach

NBEAL1 WDFY4

4.49e-049672SM01026
DomainInhibin_asu

BMP8B BMP8A

9.64e-0413672IPR002405
DomainDynein_heavy_chain_D4_dom

DNAH9 DNAH11

1.12e-0314672IPR024317
DomainDynein_HC_stalk

DNAH9 DNAH11

1.12e-0314672IPR024743
DomainDynein_heavy_dom-2

DNAH9 DNAH11

1.12e-0314672IPR013602
DomainDHC_N2

DNAH9 DNAH11

1.12e-0314672PF08393
DomainMT

DNAH9 DNAH11

1.12e-0314672PF12777
DomainAAA_8

DNAH9 DNAH11

1.12e-0314672PF12780
DomainATPase_dyneun-rel_AAA

DNAH9 DNAH11

1.12e-0314672IPR011704
DomainAAA_5

DNAH9 DNAH11

1.12e-0314672PF07728
DomainDHC_fam

DNAH9 DNAH11

1.29e-0315672IPR026983
DomainDynein_heavy_dom

DNAH9 DNAH11

1.29e-0315672IPR004273
DomainDynein_heavy

DNAH9 DNAH11

1.29e-0315672PF03028
DomainTGFb_propeptide

BMP8B BMP8A

4.51e-0328672PF00688
DomainTGF-b_N

BMP8B BMP8A

4.51e-0328672IPR001111
DomainTGF-beta-rel

BMP8B BMP8A

5.87e-0332672IPR015615
DomainTGFb_CS

BMP8B BMP8A

5.87e-0332672IPR017948
Domain-

FUCA1 KLB

6.99e-03356723.20.20.80
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K

9.85e-1199539M46448
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

8.10e-3111691116863688
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3G TBC1D3B TBC1D3F

1.43e-107469716625196
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3 TBC1D3D TBC1D3F

2.99e-0846938406013
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3 TBC1D3D TBC1D3F

2.99e-08469312359748
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C

7.45e-08569312604796
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3 TBC1D3D TBC1D3F

7.45e-0856938471161
Pubmed

New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.

BMP8B BMP8A DMPK

2.68e-061469311526197
Pubmed

Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.

BMP8B BMP8A

3.88e-06269231940275
Pubmed

The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells.

BMP8B BMP8A

3.88e-06269221277400
Pubmed

Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.

BMP8B BMP8A

3.88e-0626929463357
Pubmed

The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

3.88e-0626928682296
Pubmed

Prestin regulation and function in residual outer hair cells after noise-induced hearing loss.

SLC26A5 TECTA

3.88e-06269224376553
Pubmed

Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

1.16e-0536929076678
Pubmed

Requirement of Bmp8b for the generation of primordial germ cells in the mouse.

BMP8B BMP8A

1.16e-05369210894154
Pubmed

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).

BMP8B BMP8A

1.16e-05369212925636
Pubmed

Prognostic value of histone marks H3K27me3 and H3K9me3 and modifying enzymes EZH2, SETDB1 and LSD-1 in colorectal cancer.

SETDB1 KDM1A

1.16e-05369230105513
Pubmed

BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions.

BMP8B BMP8A

1.16e-05369222579288
Pubmed

Mutation in Bmp7 exacerbates the phenotype of Bmp8a mutants in spermatogenesis and epididymis.

BMP8B BMP8A

1.16e-05369211784057
Pubmed

Deficient forward transduction and enhanced reverse transduction in the alpha tectorin C1509G human hearing loss mutation.

SLC26A5 TECTA

1.16e-05369220142329
Pubmed

Diversity of human copy number variation and multicopy genes.

TBC1D3E TBC1D3G

1.16e-05369221030649
Pubmed

Immunohistochemistry for histone h3 lysine 9 methyltransferase and demethylase proteins in human melanomas.

SETDB1 KDM1A

1.16e-05369224658378
Pubmed

Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a.

BMP8B BMP8A

1.16e-05369225451979
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

2.32e-05469236140829
Pubmed

Characterization and chromosomal localization of PTPRO, a novel receptor protein tyrosine phosphatase, expressed in hematopoietic stem cells.

BMP8B BMP8A

2.32e-0546929434160
Pubmed

Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development.

BMP8B BMP8A

2.32e-0546928843393
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH9 DNAH11

3.86e-05569226909801
Pubmed

Forkhead box a2 (FOXA2) is essential for uterine function and fertility.

BMP8B GCM1 BMP8A

3.91e-053369328049832
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH9 DNAH11

5.79e-05669233347437
Pubmed

Conserved chromosomal location and genomic structure of human and mouse fatty-acid amide hydrolase genes and evaluation of clasper as a candidate neurological mutation.

BMP8B BMP8A

5.79e-0566929878243
Pubmed

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development.

BMP8B BMP8A

5.79e-0566927605753
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SETDB1 CACTIN RASAL3 AGO3 AKAP17A CHD9 CLSTN2 POLDIP2 KDM1A DMAP1

6.78e-051116691031753913
Pubmed

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

CDC42BPG DMPK

8.09e-05769229162624
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH9 DNAH11

8.09e-05769231178125
Pubmed

The Bmp8 gene is expressed in developing skeletal tissue and maps near the Achondroplasia locus on mouse chromosome 4.

BMP8B BMP8A

8.09e-0576929070944
Pubmed

Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat.

BMP8B BMP8A

8.09e-05769212107726
Pubmed

Gene structure and evolution of testicular haploid germ cell-specific genes, Oxct2a and Oxct2b.

BMP8B BMP8A

1.38e-04969215028287
Pubmed

Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis.

BMP8B BMP8A

1.38e-0496921460021
Pubmed

Esco2 is a novel corepressor that associates with various chromatin modifying enzymes.

SETDB1 KDM1A

1.73e-041069218501190
Pubmed

Cohesion establishment factor, Eco1 represses transcription via association with histone demethylase, LSD1.

SETDB1 KDM1A

1.73e-041069220331966
Pubmed

Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.

BMP8B BMP8A

2.11e-041169210721728
Pubmed

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.

DNAAF3 DNAH9

2.11e-041169224421334
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

MOGS P2RY6 DMPK KDM1A FN3K

2.25e-0427669528319085
Pubmed

Bmp7 regulates germ cell proliferation in mouse fetal gonads.

BMP8B BMP8A

2.98e-041369218391523
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

CACTIN MOGS SCAF8 POLDIP2 DMAP1

3.31e-0430069528561026
Pubmed

Abnormal labyrinthine zone in the Hectd1-null placenta.

GCM1 HECTD1

3.48e-041469226907377
Pubmed

Global comparative transcriptome analysis of cartilage formation in vivo.

BMP8B BMP8A

4.57e-041669219272164
Pubmed

Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.

BMP8B BMP8A

5.18e-041769214736746
Pubmed

Dysfunction of programmed embryo senescence is linked to genetic developmental defects.

BMP8B BMP8A

5.81e-041869237017267
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

SETDB1 BMP8B FUCA1 SH2D2A BMP8A SSR2 KDM1A DMAP1

9.81e-04103169816710414
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

DNAAF3 HECTD1 DNAH11

1.05e-0310069325807483
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

CLSTN2 WDFY4 CACNA2D3

1.08e-0310169318519826
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

AGO3 MAGEE1 WDFY4

1.08e-0310169310997877
Pubmed

Gse1, a component of the CoREST complex, is required for placenta development in the mouse.

CLEC2L GCM1

1.13e-032569237019373
Pubmed

Aberrant differentiation of second heart field mesoderm prefigures cellular defects in the outflow tract in response to loss of FGF8.

CLEC2L GCM1

1.22e-032669237060937
Pubmed

Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation.

BMP8B KLB

1.22e-032669230352954
Pubmed

Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling.

BMP8B NGEF BMP8A

1.31e-0310869331202927
Pubmed

Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps.

CLSTN2 HS3ST2

1.42e-032869217698011
Pubmed

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

TBC1D3 TBC1D3F

1.85e-033269223535730
Pubmed

Primary Ciliary Dyskinesia

DNAAF3 DNAH11

1.85e-033269220301301
Pubmed

A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.

CLSTN2 DNAH9

1.85e-033269223049088
Pubmed

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis.

BMP8B BMP8A

1.97e-033369232640236
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

4.49e-161496911chr17q12
Cytoband17q12

TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F

4.24e-079969517q12
Cytoband1p34

AGO3 FUCA1 DMAP1

1.56e-05326931p34
CytobandEnsembl 112 genes in cytogenetic band chr1p34

BMP8B AGO3 BMP8A DMAP1

1.03e-03294694chr1p34
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 WDFY4

1.53e-0493821230
GeneFamilyBone morphogenetic proteins|Astacins

BMP8B BMP8A

2.34e-0411382455
GeneFamilyDyneins, axonemal

DNAH9 DNAH11

5.73e-0417382536
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.35e-1190699PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D IL17RA TBC1D3G TBC1D3C TBC1D3B EDNRA TBC1D3K TBC1D3F

3.42e-102426911PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D IL17RA TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.70e-092136910PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D IL17RA TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.70e-092136910PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D IL17RA TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.40e-082816910PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D IL17RA TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.40e-082816910PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B EDNRA TBC1D3K TBC1D3F

8.13e-083206910PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

CDC42BPG TBC1D3 TBC1D3H TBC1D3L TBC1D3D PEPD FUCA1 LCAT TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F KLB

5.74e-0610496914PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

P2RY6 HLA-DOA CLSTN2 FUCA1 WDFY4

5.15e-061616952f068ee643de2f647c289779a6624265ab9a749b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related|GW23 / Sample Type, Dataset, Time_group, and Cell type.

DNAAF3 P2RY6 C22orf39 SLC5A12 DNAH11

6.52e-0616969529db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC|GW23 / Sample Type, Dataset, Time_group, and Cell type.

DNAAF3 P2RY6 C22orf39 SLC5A12 DNAH11

6.52e-06169695b1611e61f635f8f9b87250e026ad30999cbee041
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NGEF CLSTN2 TECTA HS3ST2 VWA2

8.16e-061776954c069f0d044a96118090b85ca592a21d6b5d9399
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NGEF CLSTN2 TECTA HS3ST2 VWA2

9.10e-0618169508f44323bf71b6004a921bbc969c954c75feeb66
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN MYCBPAP DNAH9 EDNRA

9.10e-06181695c1b1e62440805800a3a600b1ddd79be1c9762598
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN MYCBPAP DNAH9 DNAH11

9.85e-06184695264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

P2RY6 HLA-DOA CLSTN2 FUCA1 WDFY4

9.85e-06184695ee295f6fa898da53883e1358b17f2c2dd177e9a7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN MYCBPAP DNAH9 DNAH11

9.85e-06184695d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN MYCBPAP DNAH9 DNAH11

9.85e-0618469522010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell10x5'-Liver-Myeloid_Dendritic-DC1|Liver / Manually curated celltypes from each tissue

CLEC2L P2RY6 HLA-DOA CLSTN2 WDFY4

1.04e-05186695e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCell10x5'-Liver-Myeloid_Dendritic|Liver / Manually curated celltypes from each tissue

P2RY6 HLA-DOA CLSTN2 WDFY4 CACNA2D3

1.27e-05194695e6391bc7073831847c469ef0b0c437118e1f151f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NBEAL1 PXDNL BMP8A VWA2 EDNRA

1.37e-051976952872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MOGS NGEF SH2D2A EDNRA KLB

1.47e-05200695fe772d98c461c973dfc082e1fc50117c27ced804
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_A|TCGA-Thymus / Sample_Type by Project: Shred V9

CDC42BPG FUCA1 TECTA VWA2

7.20e-051436942d77eaa8b4d8d2cec3f3e52d73502b3e2150f925
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY6 HLA-DOA WDFY4 CACNA2D3

1.03e-04157694e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B RASAL3 HLA-DOA SLC5A12

1.03e-041576947fdc0094dd5729990a91a30c1982a14c74650b52
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B RASAL3 HLA-DOA SLC5A12

1.03e-04157694c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP8B RASAL3 HLA-DOA SLC5A12

1.03e-041576946b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

P2RY6 HLA-DOA WDFY4 CACNA2D3

1.06e-04158694e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellSubstantia_nigra-Hematopoietic|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RASAL3 P2RY6 POLE WDFY4

1.11e-0416069419d71d02f06f34eff37d268a78e5eed34da4ca44
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CDC42BPG P2RY6 DMPK CACNA2D3

1.14e-041616941670108afc0af90861eb80a84e59995571c0da1b
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CDC42BPG P2RY6 DMPK CACNA2D3

1.14e-041616941d446f5ba57d84949823a35cbedaee8f448fe40f
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASAL3 HLA-DOA SH2D2A WDFY4

1.14e-041616947e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 CLEC2L HLA-DOA PEPD

1.19e-041636942a561aa4518cf52d8470eff083b84f942a2b2b5d
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NGEF CLSTN2 TECTA DNAH11

1.19e-041636941e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 P2RY6 DMPK WDFY4

1.34e-0416869404e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCellfacs-Trachea-nan-18m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY6 HLA-DOA PEPD WDFY4

1.37e-04169694c6ae131f0bfb757541322691311139fae8bdca21
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IQCA1L P2RY6 HLA-DOA CACNA2D3

1.40e-041706947bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IQCA1L P2RY6 HLA-DOA CACNA2D3

1.40e-04170694a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NGEF MYCBPAP DNAH9 DNAH11

1.50e-04173694c3762655caa79ac4879876f470d32578a3c93b01
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC-DC2|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TBC1D3L P2RY6 NBEAL1 CACNA2D3

1.54e-0417469460ee7c6f1b6972e6647a16848087cc60e0060bbe
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLEC2L TECTA HS3ST2 VWA2

1.54e-0417469499eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAAF3 P2RY6 HLA-DOA WDFY4

1.60e-041766947d1e2627d7ec5ddd6c87c55d2a6879255b76949e
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

P2RY6 CLSTN2 FUCA1 WDFY4

1.60e-04176694195393b38f1335f2cb96125616d75c164a6026c2
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CLSTN2 TECTA HS3ST2 VWA2

1.60e-0417669472a2a01618ce836bc843395d5095e9090759b4a6
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN DNAH9 DNAH11

1.64e-04177694e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN MYCBPAP DNAH9

1.64e-04177694ae01c19403a09f7ba5e4beafdfcd1b8eebdadcb7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN MYCBPAP DNAH9

1.64e-04177694bd3d07bdef6e903995d4bbfb6ff3a5e1d9fb70cc
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN DNAH9 DNAH11

1.68e-04178694b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

DNAAF3 MYCBPAP DNAH9 DNAH11

1.68e-04178694d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN DNAH9 DNAH11

1.68e-04178694579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NGEF CLSTN2 HS3ST2 VWA2

1.71e-04179694f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RY6 IL17RA WDFY4 CACNA2D3

1.71e-04179694ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NGEF CLSTN2 HS3ST2 VWA2

1.75e-04180694b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell390C-Myeloid-Dendritic-cDC1|390C / Donor, Lineage, Cell class and subclass (all cells)

P2RY6 HLA-DOA FUCA1 WDFY4

1.79e-04181694d1c69171600b2d2aec96fa86fa757b588c265f7c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

P2RY6 NGEF CLSTN2 HS3ST2

1.82e-04182694cc6f9d606a4f8717dc44928ceec2a257636043fd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN MYCBPAP DNAH9

1.82e-04182694587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CRYGN MYCBPAP DNAH9

1.82e-04182694adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NGEF CLSTN2 HS3ST2 VWA2

1.86e-0418369465f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-DC1|lymph-node_spleen / Manually curated celltypes from each tissue

P2RY6 CLSTN2 FUCA1 WDFY4

1.86e-04183694c9e3d91f4c3395a73295b92e25608e0effb5d241
ToppCell10x5'v1-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DNAAF3 CLEC2L XIRP2 FN3K

1.86e-041836949c66a40c355387f805dbdca4162dd05af5c1d8d4
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 RASAL3 HLA-DOA WDFY4

1.86e-0418369420f7b6ec2462032eda957a893ca76d5a5a01333d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

P2RY6 HLA-DOA FUCA1 WDFY4

1.90e-04184694667846c422cfa27e949a24844a305df859cb6760
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 RASAL3 HLA-DOA SH2D2A

1.90e-041846945cf7447faaec99fc37dfa8e92ff72cc2c7c05951
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBK1 RASAL3 HLA-DOA SH2D2A

1.90e-041846947126261a453c7e2f3f005016873b6adeb51e46f8
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY6 HLA-DOA FUCA1 WDFY4

1.90e-04184694a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAAF3 MYCBPAP DNAH9 DNAH11

1.94e-041856945e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCOVID_vent-Myeloid-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

P2RY6 HLA-DOA WDFY4 CACNA2D3

1.98e-0418669463a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell10x5'-Liver-Myeloid_Dendritic-DC2|Liver / Manually curated celltypes from each tissue

P2RY6 HLA-DOA PXDNL CACNA2D3

1.98e-0418669492ef569c8f864d3abaa087cd3ce0366e8f9f50c2
ToppCellCOVID_vent-Myeloid-Dendritic-cDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

P2RY6 HLA-DOA WDFY4 CACNA2D3

1.98e-0418669439457a7b43537f2c3e221f9375c95d4515424d7d
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 MYCBPAP DNAH9 DNAH11

2.02e-041876942b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellCOVID_non-vent-Myeloid-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.02e-04187694936aaca144b79a809617cbe3058bf434a4b3d46a
ToppCell10x5'v1-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DNAAF3 CLEC2L XIRP2 FN3K

2.02e-0418769434cad5ac8602fe88ca3d421257190c9a388d4cb0
ToppCellwk_08-11-Hematologic-Myeloid-DC1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

P2RY6 HLA-DOA TBC1D3G WDFY4

2.02e-041876942907cc0b8789c5e1468917caa21fa0feb025305e
ToppCellCOVID_non-vent-Myeloid-Dendritic-cDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.02e-0418769455fe4e8b4f301876716c1af15c34d42164f2358e
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DNAAF3 CLEC2L XIRP2 FN3K

2.06e-04188694c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAAF3 MYCBPAP DNAH9 DNAH11

2.11e-04189694dc440015949a768188c67661b6be63b1ead1a0f0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NGEF PEPD CLSTN2 SLC5A12

2.11e-04189694204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NGEF PEPD CLSTN2 SLC5A12

2.11e-0418969413fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell(01)_Dendritic_cell|World / immune cells in Peripheral Blood (logTPM normalization)

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.19e-041916941f4c8078e1a6cd14937c714330af608caced2acf
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.19e-04191694aa9c0b1b90cdb7a95d4e6332819f82cae0a79ff9
ToppCellCOVID-19-Myeloid-DC1|COVID-19 / Condition, Lineage and Cell class

P2RY6 HLA-DOA FUCA1 WDFY4

2.19e-041916949e44357cdeca46d2b26124bb063c8422ef930083
ToppCellVE-mDC1-|VE / Condition, Cell_class and T cell subcluster

P2RY6 HLA-DOA FUCA1 WDFY4

2.28e-041936945df6033bc0e4f96a20d526486a8e89c990e21831
ToppCellMS-mDC1|MS / Condition, Cell_class and T cell subcluster

P2RY6 HLA-DOA FUCA1 WDFY4

2.28e-041936944d08ebf555954d6a873a4b4c4d661dc5dd8a5bcb
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY6 HLA-DOA IL17RA WDFY4

2.28e-04193694697518bab1338dc441b2d93b410d957e692f20e6
ToppCellMS-mDC1-|MS / Condition, Cell_class and T cell subcluster

P2RY6 HLA-DOA FUCA1 WDFY4

2.28e-04193694ce873f20b93e3b57c9385ee10d4becebe32ada06
ToppCellVE-mDC1|VE / Condition, Cell_class and T cell subcluster

P2RY6 HLA-DOA FUCA1 WDFY4

2.28e-0419369412b2708db9db8b88365b8ebeb4908f28c50081bb
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.33e-04194694b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.33e-041946942210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.33e-0419469474d588de2f84a4ef112fd642f7e112a542d5ef11
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.33e-0419469459180fe75be386530f1be668a37e4ada2eb19ddc
ToppCell(010)_cDC|World / immune cells in Peripheral Blood (logTPM normalization)

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.37e-041956944aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.37e-041956944cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCellhealthy_donor-Myeloid-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.42e-04196694ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCellCOVID-mDC2|COVID / Condition, Cell_class and T cell subcluster

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.42e-04196694bb13926bb664be917017edb0ce7f184abe31744b
ToppCellCOVID-mDC2-|COVID / Condition, Cell_class and T cell subcluster

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.42e-041966946d02a4c5c19be7e036150cf945585cf5a773bc87
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.42e-04196694fe7410c639fe4d7df3f6dcdb058b9a38b712927e
ToppCellhealthy_donor-Myeloid-Dendritic-cDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.42e-04196694aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.47e-0419769489fe4885efc8db142c0dc0506840ae8aceba9ef9
ToppCellHealthy_donor-cDC|Healthy_donor / disease group, cell group and cell class (v2)

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.47e-04197694b57a27e5b855bbdd1dfa352540599d260dc482aa
ToppCelldistal-Hematologic-Platelet/Megakaryocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAAF3 MYCBPAP DNAH9 DNAH11

2.47e-04197694751ffb8792058384079ebfe94872b3525f1aea84
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLSTN2 MYCBPAP DNAH9 DNAH11

2.47e-0419769474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCelldistal-Hematologic-Platelet/Megakaryocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DNAAF3 MYCBPAP DNAH9 DNAH11

2.47e-04197694e28b1b154d9588dce07c123b36f7f01fa90a5fc1
ToppCellMonocytes-cDCs|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.47e-0419769415cb9fe1c3bab80bd24728fd9ac7ba385912ac33
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.47e-041976943388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCellHealthy/Control-cDC|World / Disease group and Cell class

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.47e-041976944497d4073f4d3e74de907325fba9eb4af5766bf4
ToppCellDendritic_cell|World / shred by cell class for turbinate

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.47e-04197694ab2213e3742f92798922ea318d76328b6ca18b13
ToppCellHealthy/Control-cDC|Healthy/Control / Disease group and Cell class

P2RY6 HLA-DOA WDFY4 CACNA2D3

2.47e-04197694926423aae9fcf654f84b0f7621103a6a22d3aced
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CLEC2L P2RY6 HLA-DOA WDFY4

2.47e-0419769481dd7f9318f0ba175352e5156c24772427e0b34f
DiseaseX-24307 measurement

RASAL3 DNAH9

4.20e-062612EFO_0800871
DiseasePrimary Ciliary Dyskinesia

DNAAF3 DNAH9 DNAH11

1.28e-0447613C4551720
Diseasemacrophage inflammatory protein 1b measurement

TBC1D3 SH2D2A TBC1D3B TBC1D3F

1.84e-04136614EFO_0008219
DiseaseKartagener syndrome (implicated_via_orthology)

DNAAF3 DNAH11

3.76e-0414612DOID:0050144 (implicated_via_orthology)
Diseaselung cancer (is_implicated_in)

SETDB1 POLE HS3ST2

4.91e-0474613DOID:1324 (is_implicated_in)
Diseaseresponse to acetylsalicylate

DNAAF3 SH2D2A

4.95e-0416612GO_1903492
DiseaseCCL4 measurement

TBC1D3 TBC1D3F

7.80e-0420612EFO_0004751
Diseasediabetes mellitus (implicated_via_orthology)

BMP8B BMP8A

1.32e-0326612DOID:9351 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RGQFEEARAHWPTSF

ADAT3

136

Q96EY9
VDHEVPFSSFFIGWR

C22orf39

11

Q6P5X5
RPWDFQSHLVFCRFD

DNAH11

451

Q96DT5
LLAGRWPFDHNDFGV

EDNRA

141

P25101
GREVWFGFHQSVRPA

AGO3

196

Q9H9G7
DHFWRPAAQFESARG

CLSTN2

641

Q9H4D0
DFRIWNRGDFPFRIG

NBEAL1

1006

Q6ZS30
PGQLFWAERFHFEAL

RASAL3

346

Q86YV0
RQESFFHWAFGVTEP

PEPD

66

P12955
FRNHPFFEGVDWERL

CDC42BPG

331

Q6DT37
WGTFRFERPDGSHFD

POLDIP2

331

Q9Y2S7
EPHFFDRNYGRGLDW

HS3ST2

146

Q9Y278
RWRFTFSHFVVDPDQ

IL17RA

141

Q96F46
ARAFAEGWQALPHFR

MAGEE1

696

Q9HCI5
WAPFHIDRLFFSFVE

NMUR2

281

Q9GZQ4
TARFFHPEEWADLFQ

FUCA1

111

P04066
FFDWPFVEARAAVHG

POLE

366

Q07864
QFILEHGDYPDFFRW

CRYGN

61

Q8WXF5
HPFFFGLDWDGLRDS

DMPK

336

Q09013
RSFFPRGFLWDEGFH

MOGS

441

Q13724
NQRRFPGHLFWDFQI

CBLL1

81

Q75N03
LRDGDRFWYENPGVF

PXDNL

1226

A1KZ92
VFDPDRGQFDWTKFR

CHD9

1856

Q3L8U1
WEDFELVNPHRARFL

HECTD1

2346

Q9ULT8
FDRVFWDPSVNLFGH

KDM1A

666

O60341
EAVWRLPEFGDFARF

HLA-DOA

66

P06340
HPQEFRRWRDTGVAF

DNAAF3

226

Q8N9W5
FNADHFPLWYRRAAE

CACNA2D3

761

Q8IZS8
FFHWRRAAEEGKDYP

DMAP1

111

Q9NPF5
VDFRRLGEEFCHWFF

C3orf38

136

Q5JPI3
FPVTNFWRHDGRFIF

GCM1

131

Q9NP62
RALGHQEPHWKEFRF

BMP8A

116

Q7Z5Y6
AERFLQFEIAWFAEP

KLB

761

Q86Z14
DFQRFFADLHFEEGW

LCAT

301

P04180
RKPRFFNRVHTGFEW

CACTIN

641

Q8WUQ7
QFWEQFHKEAPFRFD

DNAH9

1236

Q9NYC9
RALGHQEPHWKEFRF

BMP8B

116

P34820
PWNRGFGQEVHRDFD

SCAF8

1136

Q9UPN6
AFFEEFVRWQRGRLP

SBK1

261

Q52WX2
HWPFGDFACRLVRFL

P2RY6

91

Q15077
AAPAWFHGFITRREA

SH2D2A

91

Q9NP31
RFFENPALWELLFHS

SLC26A5

691

P58743
RQWFIECHDLTGRFP

IQCA1L

301

A6NCM1
QDDWPTFFARHRLQA

FN3K

161

Q9H479
FGERLHDQERGWFPS

NGEF

651

Q8N5V2
DLDVEGPWFRHYDFR

TBC1D3L

461

B9A6J9
FVDTHDLRFPWVAFF

SETDB1

1236

Q15047
FPTRHDWDSFFRDAK

AKAP17A

121

Q02040
RVGDEFHWVNGDPFD

CLEC2L

161

P0C7M8
GDPAHFLFRDSWEQT

C11orf53

96

Q8IXP5
DGRAFVAPFWADVHN

TECTA

91

O75443
DLDVEGPWFRHYDFR

TBC1D3B

461

A6NDS4
DLDVEGPWFRHYDFR

TBC1D3H

461

P0C7X1
NEINRWFREFEHGPV

XIRP2

3156

A4UGR9
QREFDRRFSPHFLDW

SSR2

136

P43308
RRFSPHFLDWAAFGV

SSR2

141

P43308
DLDVEGPWFRHYDFR

TBC1D3F

461

A6NER0
FAVGVRFPRWEELHA

VWA2

181

Q5GFL6
ALHWDPVNGYFFRRN

WDFY4

691

Q6ZS81
FREFWEFRTHPTLLG

MYCBPAP

511

Q8TBZ2
DLDVEGPWFRHYDFR

TBC1D3E

461

A0A087X179
DLDVEGPWFRHYDFR

TBC1D3D

461

A0A087WVF3
FDFDVDPLRRHTFWT

SLC5A12

226

Q1EHB4
DLDVEGPWFRHYDFR

TBC1D3G

461

Q6DHY5
DLDVEGPWFRHYDFR

TBC1D3

461

Q8IZP1
EGWNRRNVDPFHIYF

TRMT10C

231

Q7L0Y3
DLDVEGPWFRHYDFR

TBC1D3K

461

A0A087X1G2
PAFWAHFARLFGDEA

TYSND1

141

Q2T9J0
HFARLFGDEAAEQWR

TYSND1

146

Q2T9J0
DLDVEGPWFRHYDFR

TBC1D3I

461

A0A087WXS9
DLDVEGPWFRHYDFR

TBC1D3C

461

Q6IPX1
SDSWEAFRRFPAFGH

KLHL42

476

Q9P2K6