Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone binding	ING3 BRD2 BRDT NAP1L3 KMT2A MLLT3 CHD8 CBX2	3.37e-07	265	51	8	GO:0042393
GeneOntologyMolecularFunction	modification-dependent protein binding	ING3 BRD2 BRDT KMT2A MLLT3 CHD8 CBX2	8.85e-07	206	51	7	GO:0140030
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD2 BRDT KMT2A MLLT3	9.85e-07	30	51	4	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD2 BRDT KMT2A MLLT3	1.13e-06	31	51	4	GO:0140033
GeneOntologyMolecularFunction	chromatin binding	TNRC18 BRD2 NFE2L1 NAP1L3 KMT2A MLLT3 CHD8 E2F4 NKX6-1 CBX2	1.47e-05	739	51	10	GO:0003682
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1A KMT2A	1.77e-04	8	51	2	GO:0140945
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	SETD1A KMT2A PRDM2	1.93e-04	44	51	3	GO:0140938
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1A KMT2A	2.84e-04	10	51	2	GO:0140999
GeneOntologyMolecularFunction	transcription regulator activator activity	MBTPS2 JMJD6	2.84e-04	10	51	2	GO:0140537
GeneOntologyMolecularFunction	histone modifying activity	SETD1A ING3 JMJD6 KMT2A PRDM2	2.90e-04	229	51	5	GO:0140993
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	SETD1A KMT2A PRDM2	7.00e-04	68	51	3	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	SETD1A KMT2A PRDM2	7.30e-04	69	51	3	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	SETD1A KMT2A PRDM2	7.94e-04	71	51	3	GO:0042054
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1A KMT2A	1.18e-03	20	51	2	GO:0042800
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	NFE2L1 ZBTB4 DACH1 NKX6-1 PRDM2	1.32e-03	320	51	5	GO:0001227
GeneOntologyMolecularFunction	methylated histone binding	ING3 CHD8 CBX2	1.38e-03	86	51	3	GO:0035064
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	NFE2L1 ZBTB4 DACH1 NKX6-1 PRDM2	1.43e-03	326	51	5	GO:0001217
GeneOntologyMolecularFunction	methylation-dependent protein binding	ING3 CHD8 CBX2	1.48e-03	88	51	3	GO:0140034
GeneOntologyMolecularFunction	protein methyltransferase activity	SETD1A KMT2A PRDM2	2.32e-03	103	51	3	GO:0008276
GeneOntologyMolecularFunction	N-methyltransferase activity	SETD1A KMT2A PRDM2	2.45e-03	105	51	3	GO:0008170
GeneOntologyMolecularFunction	transcription corepressor activity	ATN1 RLIM CIR1 SPEN	2.76e-03	229	51	4	GO:0003714
GeneOntologyMolecularFunction	transcription coregulator activity	ATN1 BRDT PPRC1 RLIM CIR1 SPEN	2.98e-03	562	51	6	GO:0003712
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD9 CHD8	4.02e-03	37	51	2	GO:0140658
GeneOntologyBiologicalProcess	chromatin organization	SETD1A ING3 BRD2 BRDT JMJD6 RLIM NAP1L3 KMT2A CHD9 MLLT3 CHD8 PRDM2 CBX2	1.10e-07	896	49	13	GO:0006325
GeneOntologyBiologicalProcess	protein-DNA complex organization	SETD1A ING3 BRD2 BRDT JMJD6 RLIM NAP1L3 KMT2A CHD9 MLLT3 CHD8 PRDM2 CBX2	3.86e-07	999	49	13	GO:0071824
GeneOntologyBiologicalProcess	mRNA processing	ARL6IP4 PNN BRDT RNPS1 JMJD6 CIR1 ACIN1 CHD8 SRRM2 CLASRP	5.49e-07	551	49	10	GO:0006397
GeneOntologyBiologicalProcess	chromatin remodeling	SETD1A ING3 BRD2 BRDT JMJD6 RLIM NAP1L3 KMT2A CHD9 CHD8 PRDM2	1.00e-06	741	49	11	GO:0006338
GeneOntologyBiologicalProcess	RNA splicing	ARL6IP4 PNN BRDT RNPS1 JMJD6 CIR1 ACIN1 SRRM2 CLASRP	2.41e-06	502	49	9	GO:0008380
GeneOntologyBiologicalProcess	regulation of chromatin organization	SETD1A ING3 KMT2A MLLT3	2.41e-06	40	49	4	GO:1902275
GeneOntologyBiologicalProcess	mRNA metabolic process	ARL6IP4 PNN BRDT RNPS1 JMJD6 CIR1 ACIN1 CHD8 EDC4 SRRM2 CLASRP	7.79e-06	917	49	11	GO:0016071
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	ATN1 NFE2L1 ZBTB4 RLIM DACH1 CIR1 CHD8 NKX6-1 SPEN PRDM2 CBX2	2.84e-05	1053	49	11	GO:0000122
GeneOntologyBiologicalProcess	RNA processing	ARL6IP4 NOLC1 PNN BRDT RNPS1 JMJD6 NAF1 CIR1 ACIN1 CHD8 SRRM2 CLASRP	1.54e-04	1500	49	12	GO:0006396
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ING3 MBTPS2 PPRC1 JMJD6 NFE2L1 KMT2A CHD8 E2F4 NKX6-1 OLIG1 PRDM2	3.37e-04	1390	49	11	GO:0045944
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	ATN1 NFE2L1 ZBTB4 RLIM DACH1 CIR1 CHD8 NKX6-1 SPEN PRDM2 CBX2	3.56e-04	1399	49	11	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	ATN1 NFE2L1 ZBTB4 RLIM DACH1 CIR1 CHD8 NKX6-1 SPEN PRDM2 CBX2	3.88e-04	1413	49	11	GO:1902679
GeneOntologyCellularComponent	nuclear speck	ARL6IP4 SETD1A FAM193B BRD2 PNN RNPS1 DACH1 CIR1 ACIN1 SRRM2	7.51e-08	431	51	10	GO:0016607
GeneOntologyCellularComponent	nuclear body	ARL6IP4 NOLC1 SETD1A FAM193B BRD2 PNN RNPS1 ZBTB4 DACH1 CIR1 ACIN1 SRRM2 HSPB7	1.73e-07	903	51	13	GO:0016604
GeneOntologyCellularComponent	exon-exon junction complex	PNN RNPS1 ACIN1	1.76e-05	21	51	3	GO:0035145
GeneOntologyCellularComponent	ASAP complex	RNPS1 ACIN1	3.49e-05	4	51	2	GO:0061574
GeneOntologyCellularComponent	nuclear protein-containing complex	NOLC1 SETD1A ING3 PNN RNPS1 KMT2A ACIN1 MLLT3 CHD8 E2F4 SRRM2 CBX2	9.12e-05	1377	51	12	GO:0140513
GeneOntologyCellularComponent	chromatin	SETD1A ING3 BRD2 BRDT NFE2L1 NAP1L3 CHD8 E2F4 NKX6-1 OLIG1 CBX2	7.37e-04	1480	51	11	GO:0000785
GeneOntologyCellularComponent	histone methyltransferase complex	SETD1A KMT2A CHD8	8.16e-04	75	51	3	GO:0035097
GeneOntologyCellularComponent	Cajal body	NOLC1 SRRM2 HSPB7	1.13e-03	84	51	3	GO:0015030
GeneOntologyCellularComponent	methyltransferase complex	SETD1A KMT2A CHD8	2.33e-03	108	51	3	GO:0034708
GeneOntologyCellularComponent	sno(s)RNA-containing ribonucleoprotein complex	NOLC1 NAF1	2.76e-03	32	51	2	GO:0005732
GeneOntologyCellularComponent	MLL1 complex	KMT2A CHD8	2.76e-03	32	51	2	GO:0071339
GeneOntologyCellularComponent	MLL1/2 complex	KMT2A CHD8	2.94e-03	33	51	2	GO:0044665
HumanPheno	Abnormality of upper lip vermillion	SETD1A ATN1 KCNMA1 KMT2A CHD8 SRRM2 SPEN	2.63e-05	464	12	7	HP:0011339
MousePheno	decreased rib number	SETD1A BRD2 CIR1 KMT2A MLLT3 CBX2	8.75e-09	57	38	6	MP:0003345
MousePheno	abnormal rib morphology	SETD1A BRD2 PNN CIR1 KMT2A MLLT3 CBX2	5.07e-06	257	38	7	MP:0000150
MousePheno	vertebral transformation	PNN KMT2A MLLT3 MEX3B CBX2	1.12e-05	110	38	5	MP:0003036
MousePheno	abnormal vertebrae morphology	BRD2 PNN BRDT RLIM CIR1 KMT2A MLLT3 MEX3B CBX2	1.17e-05	546	38	9	MP:0000137
MousePheno	abnormal presacral vertebrae morphology	PNN BRDT CIR1 KMT2A MLLT3 CBX2	2.92e-05	225	38	6	MP:0000459
MousePheno	rib fusion	BRD2 PNN CIR1 KMT2A	5.73e-05	78	38	4	MP:0000154
MousePheno	absent costovertebral joint	BRD2 CIR1	7.16e-05	5	38	2	MP:0013913
MousePheno	vertebral fusion	BRD2 RLIM CIR1 KMT2A MLLT3	7.45e-05	163	38	5	MP:0004609
MousePheno	fused joints	BRD2 RLIM CIR1 KMT2A MLLT3	9.10e-05	170	38	5	MP:0003189
MousePheno	abnormal vertebral arch morphology	BRD2 RLIM CIR1 KMT2A MEX3B	1.02e-04	174	38	5	MP:0004599
MousePheno	abnormal vertebral column morphology	BRD2 PNN BRDT RLIM CIR1 KMT2A MLLT3 MEX3B CBX2	2.02e-04	787	38	9	MP:0004703
MousePheno	abnormal thoracic cage morphology	SETD1A BRD2 PNN CIR1 KMT2A MLLT3 CBX2	2.16e-04	463	38	7	MP:0004624
MousePheno	decreased presacral vertebrae number	BRDT CIR1 MLLT3	2.43e-04	45	38	3	MP:0000461
MousePheno	abnormal cervical vertebrae morphology	CIR1 KMT2A MLLT3 CBX2	3.04e-04	120	38	4	MP:0003048
MousePheno	abnormal synovial joint morphology	BRD2 MBTPS2 CIR1 MLLT3	3.45e-04	124	38	4	MP:0030804
MousePheno	abnormal cervical atlas morphology	KMT2A MLLT3 CBX2	3.53e-04	51	38	3	MP:0004607
MousePheno	abnormal pancreatic beta cell number	BRD2 DACH1 NKX6-1	4.18e-04	54	38	3	MP:0020578
MousePheno	abnormal sternebra number	KMT2A CBX2	5.51e-04	13	38	2	MP:0012282
MousePheno	fusion of vertebral arches	BRD2 RLIM CIR1	5.98e-04	61	38	3	MP:0004613
MousePheno	persistent trigeminal artery	BRD2 CIR1	6.41e-04	14	38	2	MP:0020500
MousePheno	abnormal costovertebral joint morphology	BRD2 CIR1	6.41e-04	14	38	2	MP:0008149
MousePheno	abnormal joint morphology	BRD2 MBTPS2 RLIM CIR1 KMT2A MLLT3	6.46e-04	397	38	6	MP:0002932
MousePheno	decreased vertebrae number	BRDT CIR1 MLLT3	6.58e-04	63	38	3	MP:0004645
MousePheno	ventricular septal defect	HEG1 BRD2 PNN JMJD6 CIR1	6.62e-04	261	38	5	MP:0010402
MousePheno	perinatal lethality	BRD2 PNN JMJD6 NFE2L1 DACH1 KMT2A MLLT3 NKX6-1 MEX3B CBX2	6.65e-04	1130	38	10	MP:0002081
Domain	Fam133	FAM133B FAM133A	7.02e-06	2	50	2	IPR026766
Domain	Chromo_domain	CHD9 CHD8 CBX2	3.51e-05	24	50	3	IPR023780
Domain	BET	BRD2 BRDT	4.20e-05	4	50	2	PF17035
Domain	NET_dom	BRD2 BRDT	4.20e-05	4	50	2	IPR027353
Domain	NET	BRD2 BRDT	4.20e-05	4	50	2	PS51525
Domain	Chromo	CHD9 CHD8 CBX2	4.49e-05	26	50	3	PF00385
Domain	CHROMO_2	CHD9 CHD8 CBX2	5.64e-05	28	50	3	PS50013
Domain	CHROMO_1	CHD9 CHD8 CBX2	5.64e-05	28	50	3	PS00598
Domain	Chromodomain-like	CHD9 CHD8 CBX2	8.48e-05	32	50	3	IPR016197
Domain	CHROMO	CHD9 CHD8 CBX2	9.31e-05	33	50	3	SM00298
Domain	Chromo/shadow_dom	CHD9 CHD8 CBX2	9.31e-05	33	50	3	IPR000953
Domain	BRK	CHD9 CHD8	1.05e-04	6	50	2	SM00592
Domain	BRK_domain	CHD9 CHD8	1.05e-04	6	50	2	IPR006576
Domain	BRK	CHD9 CHD8	1.05e-04	6	50	2	PF07533
Domain	BROMODOMAIN_2	BRD2 BRDT KMT2A	1.79e-04	41	50	3	PS50014
Domain	SET	SETD1A KMT2A PRDM2	1.79e-04	41	50	3	PF00856
Domain	BROMO	BRD2 BRDT KMT2A	1.93e-04	42	50	3	SM00297
Domain	Bromodomain	BRD2 BRDT KMT2A	1.93e-04	42	50	3	IPR001487
Domain	-	BRD2 BRDT KMT2A	1.93e-04	42	50	3	1.20.920.10
Domain	SET	SETD1A KMT2A PRDM2	2.53e-04	46	50	3	SM00317
Domain	RRM	SETD1A RNPS1 PPRC1 ACIN1 SPEN	2.80e-04	217	50	5	SM00360
Domain	SET_dom	SETD1A KMT2A PRDM2	3.24e-04	50	50	3	IPR001214
Domain	SET	SETD1A KMT2A PRDM2	3.24e-04	50	50	3	PS50280
Domain	RRM_dom	SETD1A RNPS1 PPRC1 ACIN1 SPEN	3.44e-04	227	50	5	IPR000504
Domain	-	SETD1A RNPS1 PPRC1 ACIN1 SPEN	4.79e-04	244	50	5	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	SETD1A RNPS1 PPRC1 ACIN1 SPEN	6.17e-04	258	50	5	IPR012677
Domain	Post-SET_dom	SETD1A KMT2A	8.23e-04	16	50	2	IPR003616
Domain	PostSET	SETD1A KMT2A	8.23e-04	16	50	2	SM00508
Domain	POST_SET	SETD1A KMT2A	8.23e-04	16	50	2	PS50868
Domain	Bromodomain_CS	BRD2 BRDT	2.19e-03	26	50	2	IPR018359
Domain	RRM_1	SETD1A RNPS1 PPRC1 SPEN	2.31e-03	208	50	4	PF00076
Domain	AT_hook	KMT2A CBX2	2.36e-03	27	50	2	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2A CBX2	2.36e-03	27	50	2	IPR017956
Domain	LisH	NOLC1 RANBP10	2.54e-03	28	50	2	IPR006594
Domain	LisH	NOLC1 RANBP10	2.54e-03	28	50	2	SM00667
Domain	LISH	NOLC1 RANBP10	2.54e-03	28	50	2	PS50896
Domain	SNF2_N	CHD9 CHD8	3.31e-03	32	50	2	PF00176
Domain	SNF2_N	CHD9 CHD8	3.31e-03	32	50	2	IPR000330
Domain	RRM	SETD1A RNPS1 PPRC1 SPEN	3.31e-03	230	50	4	PS50102
Domain	BROMODOMAIN_1	BRD2 BRDT	4.41e-03	37	50	2	PS00633
Domain	Bromodomain	BRD2 BRDT	4.64e-03	38	50	2	PF00439
Domain	Znf_FYVE_PHD	ING3 ZBTB4 KMT2A	7.15e-03	147	50	3	IPR011011
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	NOLC1 RANBP10 BRD2 PNN BRDT JMJD6 NAF1 DACH1 KMT2A ACIN1 CHD9 CHD8 SRRM2	6.23e-13	533	51	13	30554943
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	ARL6IP4 FAM133B NOLC1 SETD1A BRD2 KMT2A ACIN1 CHD8 SPEN	1.07e-10	251	51	9	31076518
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RANBP10 SETD1A FAM193B TNRC18 HEG1 BRD2 PPRC1 ZBTB4 CHD8 EDC4 SPEN ZNF865 ARHGAP33 CBX2	4.25e-10	1105	51	14	35748872
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	SETD1A BRD2 PNN KMT2A ACIN1 CHD8 EDC4 SPEN	4.38e-10	195	51	8	19454010
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NOLC1 BRD2 ATN1 PNN RNPS1 NAF1 KMT2A ACIN1 SRRM2 SPEN PRDM2 CLASRP	9.73e-10	774	51	12	15302935
Pubmed	Human transcription factor protein interaction networks.	NOLC1 SETD1A ING3 BRD2 ATN1 PNN RLIM DACH1 KMT2A CHD8 EDC4 SRRM2 SPEN PRDM2 CBX2	1.18e-09	1429	51	15	35140242
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	ING3 PNN KMT2A ACIN1 SRRM2	4.53e-09	42	51	5	35705031
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ARL6IP4 NOLC1 ING3 BRD2 ATN1 BRDT RNPS1 JMJD6 NAF1 CHD9 CHD8 SRRM2 ARHGAP33	5.48e-09	1116	51	13	31753913
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	NOLC1 BRD2 PNN KMT2A ACIN1 SPEN	9.41e-09	103	51	6	32744500
Pubmed	The structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complex.	PNN RNPS1 ACIN1	1.19e-08	4	51	3	22388736
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	NOLC1 SETD1A BRD2 ZCCHC10 KMT2A ACIN1 CHD8 SPEN CLASRP	2.52e-08	469	51	9	27634302
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	ING3 BRD2 PNN RNPS1 NFE2L1 KMT2A CHD8 SPEN	3.32e-08	339	51	8	30415952
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	NOLC1 SETD1A KMT2A ACIN1 CHD8 EDC4 SRRM2 SPEN	3.47e-08	341	51	8	32971831
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	SETD1A PNN RNPS1 NAF1 ACIN1 MLLT3 SRRM2	1.36e-07	270	51	7	24366813
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	ARL6IP4 FAM133B NOLC1 PNN RNPS1 NAF1 ACIN1 SRRM2 SPEN MEX3B	2.31e-07	807	51	10	22681889
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ARL6IP4 NOLC1 ING3 BRD2 PNN RNPS1 KMT2A ACIN1 SRRM2 SPEN PRDM2 CLASRP	2.77e-07	1294	51	12	30804502
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	BRD2 JMJD6 KMT2A CHD9 NKX6-1 SPEN	2.89e-07	183	51	6	36129980
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	ARL6IP4 FAM133B NOLC1 SETD1A ZCCHC10 PNN RNPS1 JMJD6 KMT2A ACIN1 CHD8 SRRM2	3.37e-07	1318	51	12	30463901
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ARL6IP4 NOLC1 TNRC18 DACH1 KMT2A CHD9 CHD8 EDC4 SRRM2 SPEN PRDM2	4.62e-07	1103	51	11	34189442
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	ARL6IP4 BRD2 PNN RNPS1 JMJD6 ACIN1 EDC4 SRRM2 SPEN	4.81e-07	665	51	9	30457570
Pubmed	UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.	ARL6IP4 NOLC1 PNN RNPS1 NAF1 ACIN1 SRRM2 PHLPP2	5.57e-07	491	51	8	36273042
Pubmed	Interaction network of human early embryonic transcription factors.	SETD1A TNRC18 ATN1 KMT2A CHD8 SPEN PRDM2	7.94e-07	351	51	7	38297188
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NOLC1 BRD2 PNN DACH1 KMT2A ACIN1 CHD8 SRRM2 SPEN CBX2	1.06e-06	954	51	10	36373674
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A PNN DACH1 KMT2A ACIN1 CHD8 EDC4 SPEN	1.28e-06	549	51	8	38280479
Pubmed	The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.	NOLC1 BRD2 JMJD6 MLLT3	1.53e-06	57	51	4	21555454
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	SETD1A ING3 KMT2A CHD8 SPEN	1.60e-06	134	51	5	25452129
Pubmed	MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome.	KMT2A MLLT3	2.11e-06	2	51	2	27344946
Pubmed	Acute myeloid leukemia with t(9;11)(p21-22;q23): common properties of dysregulated ras pathway signaling and genomic progression characterize de novo and therapy-related cases.	KMT2A MLLT3	2.11e-06	2	51	2	20395514
Pubmed	Heritable genetic background alters survival and phenotype of Mll-AF9-induced leukemias.	KMT2A MLLT3	2.11e-06	2	51	2	32768438
Pubmed	Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice.	CHD8 OLIG1	2.11e-06	2	51	2	32142125
Pubmed	Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.	KMT2A MLLT3	2.11e-06	2	51	2	11265751
Pubmed	Nuclear Pnn/DRS protein binds to spliced mRNPs and participates in mRNA processing and export via interaction with RNPS1.	PNN RNPS1	2.11e-06	2	51	2	14517304
Pubmed	Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain.	CHD8 OLIG1	2.11e-06	2	51	2	33228730
Pubmed	Impact of MLL::AF9 Gene Rearrangement on Survival of Acute Myeloid Leukaemia Patients: An Insight into Pakistani Population.	KMT2A MLLT3	2.11e-06	2	51	2	38576284
Pubmed	MLL-AF9 regulates transcriptional initiation in mixed lineage leukemic cells.	KMT2A MLLT3	2.11e-06	2	51	2	39002676
Pubmed	Immune response as a possible mechanism of long-lasting disease control in spontaneous remission of MLL/AF9-positive acute myeloid leukemia.	KMT2A MLLT3	2.11e-06	2	51	2	21959947
Pubmed	MLL-AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny.	KMT2A MLLT3	2.11e-06	2	51	2	23178754
Pubmed	An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.	KMT2A MLLT3	2.11e-06	2	51	2	22427200
Pubmed	Bioflavonoids promote stable translocations between MLL-AF9 breakpoint cluster regions independent of normal chromosomal context: Model system to screen environmental risks.	KMT2A MLLT3	2.11e-06	2	51	2	30387535
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	ARL6IP4 NOLC1 PNN RNPS1 ACIN1 SRRM2	2.19e-06	259	51	6	30404004
Pubmed	Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.	ARL6IP4 NOLC1 BRD2 PNN RNPS1 ACIN1	2.24e-06	260	51	6	36199071
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ING3 BRD2 BRDT JMJD6 NFE2L1 ACIN1 E2F4 OLIG1 CBX2	2.40e-06	808	51	9	20412781
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TNRC18 ATN1 PNN RNPS1 KMT2A CHD8	2.67e-06	268	51	6	33640491
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BRD2 RNPS1 KMT2A CHD9 CHD8 SPEN PRDM2 CBX2	2.74e-06	608	51	8	36089195
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SETD1A TNRC18 ING3 ATN1 NFE2L1 SPEN MEX3B	3.05e-06	430	51	7	35044719
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	NOLC1 PNN NAF1 ACIN1 SRRM2	3.39e-06	156	51	5	22952844
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	RANBP10 TNRC18 CHD9 CHD8 SPEN CBX2	3.57e-06	282	51	6	23667531
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	ARL6IP4 PNN NAF1 ACIN1 SRRM2	4.20e-06	163	51	5	22113938
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NOLC1 PNN KMT2A ACIN1 CHD8 EDC4 SRRM2 SPEN	4.63e-06	653	51	8	22586326
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	ARL6IP4 NOLC1 TNRC18 PNN RNPS1 CIR1 ACIN1 SRRM2	4.73e-06	655	51	8	35819319
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FAM133B NOLC1 TNRC18 BRD2 PNN FAM133A RNPS1 PPRC1 KMT2A ACIN1 SPEN	6.19e-06	1442	51	11	35575683
Pubmed	FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis.	KMT2A MLLT3	6.32e-06	3	51	2	30953031
Pubmed	Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.	KMT2A MLLT3	6.32e-06	3	51	2	18538732
Pubmed	Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations.	KMT2A CBX2	6.32e-06	3	51	2	26431491
Pubmed	Loss of Acinus inhibits oligonucleosomal DNA fragmentation but not chromatin condensation during apoptosis.	RNPS1 ACIN1	6.32e-06	3	51	2	16537548
Pubmed	ASAP, a novel protein complex involved in RNA processing and apoptosis.	RNPS1 ACIN1	6.32e-06	3	51	2	12665594
Pubmed	Set1/MLL complex is indispensable for the transcriptional ability of heat shock transcription factor 2.	SETD1A KMT2A	6.32e-06	3	51	2	26478434
Pubmed	Down-regulation of MLL-AF9, MLL and MYC expression is not obligatory for monocyte-macrophage maturation in AML-M5 cell lines carrying t(9;11)(p22;q23).	KMT2A MLLT3	6.32e-06	3	51	2	16328057
Pubmed	Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing.	PNN RNPS1	6.32e-06	3	51	2	30388411
Pubmed	Rac1 signaling protects monocytic AML cells expressing the MLL-AF9 oncogene from caspase-mediated apoptotic death.	KMT2A MLLT3	6.32e-06	3	51	2	23624644
Pubmed	Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.	BRD2 BRDT	6.32e-06	3	51	2	28945351
Pubmed	High BRE expression predicts favorable outcome in adult acute myeloid leukemia, in particular among MLL-AF9-positive patients.	KMT2A MLLT3	6.32e-06	3	51	2	21937695
Pubmed	Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia.	NOLC1 E2F4	6.32e-06	3	51	2	17001309
Pubmed	The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection.	SETD1A KMT2A	6.32e-06	3	51	2	17578910
Pubmed	The adverse impact of ecotropic viral integration site-1 (EVI1) overexpression on the prognosis of acute myeloid leukemia with KMT2A gene rearrangement in different risk stratification subtypes.	KMT2A MLLT3	6.32e-06	3	51	2	36358022
Pubmed	CRISPR Gene Editing of Murine Blood Stem and Progenitor Cells Induces MLL-AF9 Chromosomal Translocation and MLL-AF9 Leukaemogenesis.	KMT2A MLLT3	6.32e-06	3	51	2	32549410
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	NOLC1 SETD1A PNN RNPS1 RLIM SPEN	6.49e-06	313	51	6	38270169
Pubmed	The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.	PNN RNPS1 CHD8 SPEN	7.26e-06	84	51	4	26299517
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	BRD2 ATN1 CHD8 SRRM2 CLASRP	1.05e-05	197	51	5	20811636
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ARL6IP4 NOLC1 TNRC18 ATN1 PNN RNPS1 ACIN1 CHD9 MLLT3 SRRM2	1.13e-05	1247	51	10	27684187
Pubmed	Relationships between AML1-ETO and MLL-AF9 fusion gene expressions and hematological parameters in acute myeloid leukemia.	KMT2A MLLT3	1.26e-05	4	51	2	33431365
Pubmed	Polycomb repressive complex 2 is required for MLL-AF9 leukemia.	KMT2A MLLT3	1.26e-05	4	51	2	22396593
Pubmed	The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.	KMT2A MLLT3	1.26e-05	4	51	2	22469984
Pubmed	Rheb1 promotes tumor progression through mTORC1 in MLL-AF9-initiated murine acute myeloid leukemia.	KMT2A MLLT3	1.26e-05	4	51	2	27071307
Pubmed	MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.	KMT2A MLLT3	1.26e-05	4	51	2	31852898
Pubmed	Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin.	SETD1A KMT2A	1.26e-05	4	51	2	34012049
Pubmed	Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model.	KMT2A MLLT3	1.26e-05	4	51	2	27607576
Pubmed	DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.	KMT2A MLLT3	1.26e-05	4	51	2	21521783
Pubmed	Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells.	PNN SRRM2	1.26e-05	4	51	2	14578391
Pubmed	Expression of BET genes in testis of men with different spermatogenic impairments.	BRD2 BRDT	1.26e-05	4	51	2	22035730
Pubmed	Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.	KMT2A MLLT3	1.26e-05	4	51	2	27374225
Pubmed	Leukaemia lineage specification caused by cell-specific Mll-Enl translocations.	KMT2A MLLT3	1.26e-05	4	51	2	17906700
Pubmed	Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis.	KMT2A MLLT3	1.26e-05	4	51	2	16096649
Pubmed	Phosphoinositide-dependent kinase 1 regulates leukemia stem cell maintenance in MLL-AF9-induced murine acute myeloid leukemia.	KMT2A MLLT3	1.26e-05	4	51	2	25769952
Pubmed	Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing.	KMT2A MLLT3	1.26e-05	4	51	2	17581865
Pubmed	Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.	PNN RNPS1 KMT2A ACIN1	1.69e-05	104	51	4	26167872
Pubmed	A conserved acetylation switch enables pharmacological control of tubby-like protein stability.	RANBP10 JMJD6 NAF1 CHD9 MLLT3	1.91e-05	223	51	5	33187986
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	CHD9 CHD8 SPEN CBX2	2.04e-05	109	51	4	33554859
Pubmed	Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.	SETD1A KMT2A	2.10e-05	5	51	2	25561738
Pubmed	[Application of reverse transcription-multiplex nested PCR to detect MLL rearrangement in AML-M4/M5].	KMT2A MLLT3	2.10e-05	5	51	2	16086288
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	TNRC18 NFE2L1 KMT2A CHD9	2.11e-05	110	51	4	26841866
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	NOLC1 BRD2 PNN ACIN1 CHD8 EDC4 SRRM2	2.17e-05	582	51	7	20467437
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SETD1A BRD2 KMT2A CHD9 CHD8 EDC4	2.38e-05	394	51	6	27248496
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	PNN RNPS1 ACIN1 SRRM2	2.51e-05	115	51	4	17332742
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	NOLC1 BRD2 PNN KMT2A ACIN1 SRRM2 SPEN	2.78e-05	605	51	7	28977666
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SETD1A PNN RNPS1 ACIN1 CHD8 SPEN	2.98e-05	410	51	6	26949251
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	ING3 BRD2 RNPS1 KMT2A CHD8 SRRM2	3.02e-05	411	51	6	35182466
Pubmed	Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.	PNN ACIN1	3.15e-05	6	51	2	16314458
Pubmed	GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation.	SETD1A KMT2A	3.15e-05	6	51	2	34933446
Pubmed	Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.	KMT2A MLLT3	3.15e-05	6	51	2	21896721
Interaction	PIP4K2A interactions	ARL6IP4 NOLC1 BRD2 ZCCHC10 PNN RNPS1 PPRC1 JMJD6 NAF1 ACIN1 CHD9 MLLT3 CHD8 EDC4 SRRM2 SPEN MEX3B CLASRP	2.27e-23	216	50	18	int:PIP4K2A
Interaction	NFKBIL1 interactions	NOLC1 SETD1A TNRC18 BRD2 ZCCHC10 PNN RNPS1 JMJD6 NAP1L3 ACIN1 CHD9 CHD8 SRRM2 SPEN	5.86e-22	93	50	14	int:NFKBIL1
Interaction	CT45A5 interactions	NOLC1 RANBP10 SETD1A BRD2 JMJD6 NAF1 DACH1 NAP1L3 CHD9 MLLT3 CHD8 EDC4 SPEN	4.84e-21	78	50	13	int:CT45A5
Interaction	CAMKV interactions	NOLC1 TNRC18 BRD2 ZCCHC10 PNN RNPS1 NAF1 ACIN1 CHD9 MLLT3 SRRM2 SPEN	9.22e-17	118	50	12	int:CAMKV
Interaction	PLCD3 interactions	NOLC1 RANBP10 SETD1A BRD2 ZCCHC10 RNPS1 NAF1 CHD9 MLLT3 CHD8 SPEN	7.05e-15	121	50	11	int:PLCD3
Interaction	SULF2 interactions	SETD1A TNRC18 BRD2 ZCCHC10 NAF1 ACIN1 CHD9 MLLT3 SRRM2 SPEN	2.95e-13	119	50	10	int:SULF2
Interaction	NKAP interactions	ING3 BRD2 ZCCHC10 PNN RNPS1 JMJD6 ACIN1 CHD9 CHD8 SRRM2	8.46e-13	132	50	10	int:NKAP
Interaction	FAM9A interactions	NOLC1 PNN RNPS1 JMJD6 NAF1 NAP1L3 MLLT3 SRRM2	1.61e-12	59	50	8	int:FAM9A
Interaction	EPB41L3 interactions	SETD1A TNRC18 ZCCHC10 PNN RNPS1 NAF1 KCNMA1 DACH1 ACIN1 CHD9 MLLT3 SRRM2	2.21e-12	272	50	12	int:EPB41L3
Interaction	DAXX interactions	NOLC1 SETD1A TNRC18 BRD2 ZCCHC10 PNN RNPS1 NAF1 CHD9 MLLT3 SRRM2 SPEN CBX2	2.32e-12	353	50	13	int:DAXX
Interaction	DENND2D interactions	NOLC1 BRD2 PNN RNPS1 ACIN1 MLLT3 SRRM2	2.95e-12	36	50	7	int:DENND2D
Interaction	BRD9 interactions	NOLC1 BRD2 ZCCHC10 PNN RNPS1 JMJD6 NFE2L1 NAF1 SRRM2	1.13e-11	117	50	9	int:BRD9
Interaction	EPB41L1 interactions	SETD1A TNRC18 BRD2 ZCCHC10 PNN RNPS1 NAF1 ACIN1 MLLT3 SRRM2	2.77e-11	187	50	10	int:EPB41L1
Interaction	MDK interactions	SETD1A TNRC18 BRD2 PNN NAF1 CHD9 MLLT3 SRRM2	5.80e-11	91	50	8	int:MDK
Interaction	SYT2 interactions	NOLC1 RANBP10 SETD1A JMJD6 NAF1 DACH1 NAP1L3 CHD9 MLLT3	1.06e-10	150	50	9	int:SYT2
Interaction	NUP43 interactions	ARL6IP4 SETD1A ATN1 PNN RNPS1 RLIM KMT2A ACIN1 CHD9 CHD8 E2F4 SRRM2 SPEN PRDM2	2.21e-10	625	50	14	int:NUP43
Interaction	CSNK2A1 interactions	ARL6IP4 NOLC1 SETD1A BRD2 ATN1 ZCCHC10 PNN FAM133A RNPS1 JMJD6 NAF1 KMT2A ACIN1 E2F4 SRRM2 CBX2	6.25e-10	956	50	16	int:CSNK2A1
Interaction	SRSF11 interactions	ARL6IP4 ZCCHC10 PNN RNPS1 JMJD6 DACH1 ACIN1 E2F4 SRRM2	1.57e-09	203	50	9	int:SRSF11
Interaction	C1orf35 interactions	ARL6IP4 BRD2 PNN FAM133A RNPS1 JMJD6 DACH1 ACIN1 CHD9 SRRM2	3.17e-09	304	50	10	int:C1orf35
Interaction	NKAPD1 interactions	ARL6IP4 ZCCHC10 PNN FAM133A RNPS1 JMJD6 ACIN1 SRRM2	5.63e-09	161	50	8	int:NKAPD1
Interaction	EDA interactions	SETD1A TNRC18 PNN RNPS1 NAF1 MLLT3 SRRM2	1.18e-08	113	50	7	int:EDA
Interaction	NOS1AP interactions	BRD2 ZCCHC10 PNN FAM133A RNPS1 NAF1 MEX3B	1.18e-08	113	50	7	int:NOS1AP
Interaction	PES1 interactions	NOLC1 SETD1A TNRC18 BRD2 PNN RNPS1 NAF1 MLLT3 SRRM2	1.27e-08	258	50	9	int:PES1
Interaction	RNF151 interactions	TNRC18 PNN FAM133A RNPS1 ACIN1 MLLT3 SRRM2	2.13e-08	123	50	7	int:RNF151
Interaction	BRD3 interactions	ARL6IP4 NOLC1 BRD2 PNN RNPS1 DACH1 KMT2A ACIN1 CHD9 CHD8 SRRM2	2.71e-08	494	50	11	int:BRD3
Interaction	BRDT interactions	RANBP10 BRD2 PNN BRDT DACH1 CHD8	4.82e-08	81	50	6	int:BRDT
Interaction	RSBN1 interactions	SETD1A BRD2 ZCCHC10 PNN RNPS1 PPRC1 ZNF865	1.36e-07	161	50	7	int:RSBN1
Interaction	AKAP17A interactions	BRD2 ZCCHC10 PNN RNPS1 JMJD6 SRRM2	1.61e-07	99	50	6	int:AKAP17A
Interaction	SRRM1 interactions	NOLC1 BRD2 ZCCHC10 PNN BRDT RNPS1 ACIN1 E2F4 SRRM2	1.65e-07	348	50	9	int:SRRM1
Interaction	CEBPA interactions	ARL6IP4 NOLC1 TNRC18 PNN RNPS1 DACH1 KMT2A ACIN1 CHD9 CHD8 E2F4 EDC4 SRRM2 SPEN PRDM2	1.94e-07	1245	50	15	int:CEBPA
Interaction	C1orf226 interactions	BRD2 ZCCHC10 FAM133A RNPS1 NAF1	2.01e-07	53	50	5	int:C1orf226
Interaction	ZCCHC17 interactions	ING3 ZCCHC10 PNN RNPS1 JMJD6 SRRM2	2.16e-07	104	50	6	int:ZCCHC17
Interaction	TOP3B interactions	RANBP10 SETD1A FAM193B TNRC18 HEG1 BRD2 PPRC1 ZBTB4 ACIN1 CHD8 EDC4 SPEN ZNF865 MEX3B ARHGAP33 CBX2	2.70e-07	1470	50	16	int:TOP3B
Interaction	POLR1G interactions	NOLC1 BRD2 DACH1 KMT2A CHD9 CHD8 E2F4 SRRM2 PRDM2 CBX2	2.78e-07	489	50	10	int:POLR1G
Interaction	PPIE interactions	ZCCHC10 PNN RNPS1 KMT2A ACIN1 CHD9 E2F4 SRRM2	4.29e-07	282	50	8	int:PPIE
Interaction	EPB41L5 interactions	SETD1A BRD2 ZCCHC10 PNN RNPS1 NAF1 CHD9 MLLT3	6.52e-07	298	50	8	int:EPB41L5
Interaction	PPIG interactions	ZCCHC10 PNN RNPS1 JMJD6 DACH1 CHD8	7.04e-07	127	50	6	int:PPIG
Interaction	SSRP1 interactions	ARL6IP4 NOLC1 BRD2 PNN RNPS1 JMJD6 KMT2A ACIN1 E2F4 SRRM2 CBX2	7.20e-07	685	50	11	int:SSRP1
Interaction	SNIP1 interactions	ARL6IP4 NOLC1 BRD2 ZCCHC10 PNN RNPS1 ACIN1 SRRM2 CLASRP	7.54e-07	417	50	9	int:SNIP1
Interaction	PLCD4 interactions	NOLC1 NAP1L3 MLLT3 CBX2	1.15e-06	32	50	4	int:PLCD4
Interaction	PRP4K interactions	BRD2 ZCCHC10 PNN RNPS1 ACIN1 E2F4 SRRM2 SPEN	1.37e-06	329	50	8	int:PRP4K
Interaction	NFIX interactions	SETD1A ING3 BRD2 JMJD6 DACH1 KMT2A SPEN	1.39e-06	227	50	7	int:NFIX
Interaction	YAP1 interactions	FAM133B SETD1A TNRC18 BRD2 ATN1 PNN DACH1 KMT2A ACIN1 CHD8 EDC4 SRRM2 SPEN	1.81e-06	1095	50	13	int:YAP1
Interaction	U2AF1 interactions	ZCCHC10 RNPS1 JMJD6 CIR1 ACIN1 SRRM2 CLASRP	1.96e-06	239	50	7	int:U2AF1
Interaction	TAF6 interactions	NOLC1 SETD1A BRD2 ZCCHC10 BRDT RNPS1 KMT2A	2.30e-06	245	50	7	int:TAF6
Interaction	LUC7L2 interactions	ZCCHC10 PNN RNPS1 JMJD6 ACIN1 E2F4 SRRM2 CLASRP	2.31e-06	353	50	8	int:LUC7L2
Interaction	DDX23 interactions	NOLC1 BRD2 PNN BRDT RNPS1 NAF1 ACIN1 SRRM2 CLASRP	2.41e-06	480	50	9	int:DDX23
Interaction	ASF1A interactions	BRD2 KMT2A CHD8 E2F4 SPEN PRDM2 CBX2	2.57e-06	249	50	7	int:ASF1A
Interaction	CSNK2B interactions	NOLC1 ING3 BRD2 BRDT FAM133A RNPS1 KMT2A CHD8 E2F4 CBX2	2.57e-06	625	50	10	int:CSNK2B
Interaction	PIP4K2C interactions	ARL6IP4 NOLC1 BRD2 ZCCHC10 RNPS1 MEX3B	2.62e-06	159	50	6	int:PIP4K2C
Interaction	CFAP20 interactions	PNN RNPS1 ACIN1 SRRM2 CLASRP	3.03e-06	91	50	5	int:CFAP20
Interaction	DDX41 interactions	BRD2 PNN RNPS1 JMJD6 SRRM2 SPEN	3.36e-06	166	50	6	int:DDX41
Interaction	PIP4K2B interactions	ARL6IP4 BRD2 ZCCHC10 RNPS1 HSPB7	3.95e-06	96	50	5	int:PIP4K2B
Interaction	NOG interactions	BRD2 PNN NAP1L3 SRRM2	4.63e-06	45	50	4	int:NOG
Interaction	ARGLU1 interactions	NOLC1 ZCCHC10 PNN JMJD6 RLIM ACIN1	4.71e-06	176	50	6	int:ARGLU1
Interaction	SREK1 interactions	ARL6IP4 ZCCHC10 PNN RNPS1 JMJD6 E2F4	5.89e-06	183	50	6	int:SREK1
Interaction	TAF7 interactions	BRD2 ZCCHC10 BRDT JMJD6 CHD8	7.04e-06	108	50	5	int:TAF7
Interaction	TAF9B interactions	BRD2 ZCCHC10 RNPS1 CHD8 EDC4	7.04e-06	108	50	5	int:TAF9B
Interaction	DHX8 interactions	ZCCHC10 PNN RNPS1 JMJD6 SRRM2 SPEN CLASRP	7.31e-06	292	50	7	int:DHX8
Interaction	COIL interactions	NOLC1 BRD2 ZCCHC10 DACH1 CHD9 MLLT3 CHD8 E2F4 CLASRP	7.49e-06	552	50	9	int:COIL
Interaction	CHD8 interactions	SETD1A BRD2 BRDT NAF1 KMT2A CHD8	7.99e-06	193	50	6	int:CHD8
Interaction	KCNE3 interactions	BRD2 PNN NAF1 NAP1L3 MLLT3 SPEN CBX2	7.99e-06	296	50	7	int:KCNE3
Interaction	CLK2 interactions	ZCCHC10 PNN RNPS1 ACIN1 SRRM2 CLASRP	8.47e-06	195	50	6	int:CLK2
Interaction	EPB41L2 interactions	SETD1A PNN RNPS1 JMJD6 ACIN1 MLLT3 SRRM2	8.53e-06	299	50	7	int:EPB41L2
Interaction	CSNK2A2 interactions	ARL6IP4 NOLC1 BRD2 PNN BRDT FAM133A RNPS1 KMT2A SRRM2 CBX2	8.75e-06	718	50	10	int:CSNK2A2
Interaction	PHF20 interactions	SETD1A ATN1 KMT2A CHD8	8.97e-06	53	50	4	int:PHF20
Interaction	PNN interactions	BRD2 PNN BRDT FAM133A RNPS1 ACIN1 SRRM2	9.10e-06	302	50	7	int:PNN
Interaction	RSBN1L interactions	BRD2 ZCCHC10 PNN RNPS1 SRRM2	9.17e-06	114	50	5	int:RSBN1L
Interaction	AFF4 interactions	ARL6IP4 NOLC1 FAM133A KMT2A MLLT3	9.57e-06	115	50	5	int:AFF4
Interaction	SMOC1 interactions	PNN RNPS1 NAF1 MLLT3	9.67e-06	54	50	4	int:SMOC1
Interaction	SAP18 interactions	NOLC1 BRD2 PNN RNPS1 ACIN1 E2F4 SRRM2	9.71e-06	305	50	7	int:SAP18
Interaction	H3C1 interactions	SETD1A TNRC18 BRD2 JMJD6 RLIM KMT2A MLLT3 CHD8 SPEN PRDM2 CBX2	1.01e-05	901	50	11	int:H3C1
Interaction	RBM33 interactions	BRD2 PNN BRDT RNPS1 ACIN1	1.04e-05	117	50	5	int:RBM33
Interaction	JMJD6 interactions	ARL6IP4 BRD2 ZCCHC10 FAM133A JMJD6 NAF1	1.13e-05	205	50	6	int:JMJD6
Interaction	H3-3A interactions	SETD1A BRD2 RNPS1 KMT2A CHD9 MLLT3 CHD8 SPEN PRDM2 CBX2	1.26e-05	749	50	10	int:H3-3A
Interaction	PRPF40A interactions	ZCCHC10 PNN FAM133A RNPS1 JMJD6 ACIN1 SRRM2 SPEN	1.28e-05	446	50	8	int:PRPF40A
Interaction	ANKRD36B interactions	ZCCHC10 CHD9 CHD8 SPEN	1.48e-05	60	50	4	int:ANKRD36B
Interaction	RAD18 interactions	ARL6IP4 FAM133B NOLC1 SETD1A BRD2 ACIN1 SRRM2 SPEN	1.53e-05	457	50	8	int:RAD18
Interaction	CLK3 interactions	PNN RNPS1 JMJD6 ACIN1 SRRM2 CLASRP	1.68e-05	220	50	6	int:CLK3
Interaction	USP42 interactions	ZCCHC10 RNPS1 JMJD6 SRRM2	2.16e-05	66	50	4	int:USP42
Interaction	SNRNP40 interactions	ATN1 PNN ZBTB4 KMT2A ACIN1 SRRM2 SPEN CLASRP CBX2	2.34e-05	637	50	9	int:SNRNP40
Interaction	KANSL2 interactions	SETD1A ATN1 ZCCHC10 KMT2A	2.72e-05	70	50	4	int:KANSL2
Interaction	U2AF2 interactions	PNN RNPS1 JMJD6 DACH1 ACIN1 CHD8 SRRM2 MEX3B CLASRP	2.78e-05	651	50	9	int:U2AF2
Interaction	CACTIN interactions	BRD2 ZCCHC10 RNPS1 JMJD6 SPEN	2.84e-05	144	50	5	int:CACTIN
Interaction	LUC7L interactions	PNN RNPS1 JMJD6 ACIN1 SRRM2 CLASRP	2.88e-05	242	50	6	int:LUC7L
Interaction	SRSF6 interactions	PNN RNPS1 KMT2A ACIN1 E2F4 SRRM2 SPEN CLASRP	3.04e-05	503	50	8	int:SRSF6
Interaction	H2AC4 interactions	SETD1A BRD2 RLIM KMT2A CHD9 CHD8 EDC4 CBX2	3.17e-05	506	50	8	int:H2AC4
Interaction	MEN1 interactions	NOLC1 SETD1A ATN1 PNN RNPS1 KMT2A ACIN1 CHD8 EDC4 SRRM2 SPEN	3.47e-05	1029	50	11	int:MEN1
Interaction	RBPJ interactions	BRD2 JMJD6 CIR1 KMT2A NKX6-1 SPEN	3.77e-05	254	50	6	int:RBPJ
Interaction	ATXN1 interactions	ARL6IP4 FAM193B BRD2 PNN RNPS1 JMJD6 ACIN1 EDC4 SRRM2 SPEN CLASRP	3.79e-05	1039	50	11	int:ATXN1
Interaction	TAF1A interactions	ZCCHC10 RNPS1 JMJD6 NAF1	4.18e-05	78	50	4	int:TAF1A
Interaction	H2BC4 interactions	ARL6IP4 NOLC1 TNRC18 PNN KMT2A SRRM2	4.21e-05	259	50	6	int:H2BC4
Interaction	TOP1 interactions	ARL6IP4 BRD2 PNN RNPS1 JMJD6 KMT2A ACIN1 SRRM2 CBX2	4.67e-05	696	50	9	int:TOP1
Interaction	FAM133A interactions	FAM133B PNN FAM133A JMJD6	4.85e-05	81	50	4	int:FAM133A
Interaction	TERF2IP interactions	SETD1A DACH1 KMT2A CHD8 E2F4 SRRM2 SPEN CBX2	5.87e-05	552	50	8	int:TERF2IP
Interaction	SARNP interactions	PNN RNPS1 ACIN1 E2F4 SRRM2	5.93e-05	168	50	5	int:SARNP
Interaction	H2BC3 interactions	SETD1A BRD2 KMT2A CHD9 CHD8 EDC4 CBX2	6.05e-05	406	50	7	int:H2BC3
Interaction	CTBP1 interactions	PNN KCNMA1 KMT2A E2F4 SRRM2 SPEN PRDM2	6.05e-05	406	50	7	int:CTBP1
Interaction	TAF5 interactions	BRD2 ZCCHC10 BRDT RNPS1	6.13e-05	86	50	4	int:TAF5
Interaction	FGF11 interactions	SETD1A CHD9 MLLT3 EDC4 SRRM2	6.28e-05	170	50	5	int:FGF11
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	RANBP10 E2F4 EDC4 PHLPP2	5.27e-05	183	51	4	chr16q22
Cytoband	10q24.32	NOLC1 PPRC1	3.29e-04	24	51	2	10q24.32
GeneFamily	ASAP complex\|SIN3 histone deacetylase complex	RNPS1 ACIN1	6.44e-06	3	27	2	1236
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A KMT2A PRDM2	1.72e-05	34	27	3	487
GeneFamily	RNA binding motif containing	SETD1A RNPS1 PPRC1 SPEN	2.66e-04	213	27	4	725
GeneFamily	PHD finger proteins	ING3 KMT2A	7.93e-03	90	27	2	88
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	SETD1A ATN1 RNPS1 PPRC1 ACIN1 SRRM2 CLASRP	3.46e-06	338	50	7	M17094
Coexpression	EPPERT_HSC_R	ZBTB4 RLIM DACH1 KMT2A MLLT3	4.39e-06	127	50	5	M19231
Coexpression	YUAN_ZNF143_PARTNERS	BRD2 PNN CHD8	9.80e-06	22	50	3	M2355
Coexpression	GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN	PPRC1 JMJD6 NFE2L1 SPEN PRDM2	3.85e-05	199	50	5	M3517
Coexpression	GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_UP	BRD2 NFE2L1 KCNMA1 DACH1 KMT2A	3.85e-05	199	50	5	M3073
Coexpression	GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP	ATN1 PPRC1 ZBTB4 SHE SRRM2	3.94e-05	200	50	5	M9258
Coexpression	MENON_FETAL_KIDNEY_4_PODOCYTES	BRD2 NFE2L1 DACH1 KMT2A SRRM2	4.54e-05	206	50	5	M39254
Coexpression	LEE_BMP2_TARGETS_DN	NOLC1 ZCCHC10 PNN RNPS1 PPRC1 JMJD6 NAF1 MLLT3 CBX2	4.66e-05	904	50	9	M2325
Coexpression	LEE_BMP2_TARGETS_DN	NOLC1 ZCCHC10 PNN RNPS1 PPRC1 JMJD6 NAF1 MLLT3 CBX2	5.43e-05	922	50	9	MM1068
Coexpression	GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_DN	RANBP10 SETD1A FAM193B KCNMA1	1.44e-04	139	50	4	M8948
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	SETD1A TNRC18 HEG1 BRD2 PNN ZBTB4 RLIM ACIN1 CHD9 CHD8 MEX3B	1.75e-06	790	50	11	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000	SETD1A HEG1 BRD2 MBTPS2 JMJD6 RLIM NAP1L3 ACIN1 CHD9 CHD8 MEX3B	2.36e-06	815	50	11	gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500	SETD1A HEG1 MBTPS2 RLIM ACIN1 CHD9 CHD8 MEX3B	4.68e-06	409	50	8	gudmap_developingGonad_e12.5_ovary_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	SETD1A TNRC18 HEG1 RLIM ACIN1 CHD9 CHD8 MEX3B	5.03e-06	413	50	8	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	SETD1A HEG1 BRD2 MBTPS2 BRDT RLIM ACIN1 CHD9 CHD8 MEX3B	1.35e-05	795	50	10	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000	SETD1A HEG1 RLIM CHD9 CHD8 MEX3B	1.43e-05	225	50	6	gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	SETD1A TNRC18 BRD2 MBTPS2 BRDT RLIM ACIN1 CHD9 CHD8 MEX3B	1.52e-05	806	50	10	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500	SETD1A HEG1 RLIM CHD8	1.66e-05	65	50	4	gudmap_developingGonad_P2_ovary_500_k2
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_500	SETD1A TNRC18 BRD2 RLIM ACIN1 CHD8 MEX3B	4.16e-05	403	50	7	gudmap_developingGonad_e12.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	SETD1A TNRC18 HEG1 ACIN1 CHD9 CHD8 MEX3B	4.36e-05	406	50	7	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	SETD1A HEG1 MBTPS2 BRDT RLIM ACIN1 CHD9 CHD8 MEX3B	7.24e-05	776	50	9	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	SETD1A HEG1 BRD2 MBTPS2 BRDT RLIM ACIN1 CHD8 MEX3B	7.39e-05	778	50	9	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_500	SETD1A HEG1 CHD8 MEX3B	8.02e-05	97	50	4	gudmap_developingGonad_e18.5_ovary_500_k3
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	SETD1A TNRC18 HEG1 BRD2 RLIM ACIN1 CHD9 CHD8 MEX3B	9.06e-05	799	50	9	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	SETD1A TNRC18 HEG1 BRD2 RLIM ACIN1 CHD9 CHD8 MEX3B	9.23e-05	801	50	9	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000	SETD1A HEG1 RLIM NAP1L3 CHD9 CHD8	1.07e-04	323	50	6	gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500	SETD1A HEG1 RLIM CHD8	1.17e-04	107	50	4	gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_500	SETD1A HEG1 CHD8 MEX3B	1.26e-04	109	50	4	gudmap_developingGonad_e16.5_ovary_500_k5
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000	SETD1A HEG1 CHD9 CHD8 MEX3B	2.03e-04	230	50	5	gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500	SETD1A HEG1 MBTPS2 BRDT CHD8 MEX3B	2.65e-04	382	50	6	gudmap_developingGonad_e14.5_ ovary_500
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500	SETD1A HEG1 MBTPS2 RLIM CHD8 MEX3B	2.85e-04	387	50	6	gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#2_top-relative-expression-ranked_200	SETD1A RLIM CHD8	4.02e-04	61	50	3	gudmap_developingGonad_e12.5_epididymis_k2_200
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500	SETD1A MBTPS2 RLIM ACIN1 CHD8 MEX3B	4.24e-04	417	50	6	gudmap_developingGonad_e11.5_ovary + mesonephros_500
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_500	SETD1A TNRC18 RLIM CHD8	4.28e-04	150	50	4	gudmap_developingGonad_e12.5_epididymis_k5_500
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000	SETD1A HEG1 RLIM CHD8	4.39e-04	151	50	4	gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	SETD1A HEG1 RLIM CHD9 CHD8	4.62e-04	275	50	5	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000	SETD1A TNRC18 HEG1 BRD2 RLIM ACIN1 CHD9 CHD8	5.05e-04	797	50	8	gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	SETD1A HEG1 MBTPS2 RLIM ACIN1 CHD9 CHD8 MEX3B	5.35e-04	804	50	8	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_500	SETD1A HEG1 CHD9 CHD8	5.59e-04	161	50	4	gudmap_developingGonad_e12.5_ovary_k3_500
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_500	SETD1A TNRC18 HEG1 CHD9	5.72e-04	162	50	4	gudmap_developingGonad_e16.5_epididymis_500_k2
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_200	SETD1A HEG1 ACIN1 CHD8	6.27e-04	166	50	4	gudmap_developingGonad_e16.5_epididymis_200
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_200	SETD1A ACIN1 CHD8 MEX3B	6.41e-04	167	50	4	gudmap_developingGonad_e14.5_ epididymis_200
CoexpressionAtlas	DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000	NOLC1 BRD2 JMJD6 ACIN1 CHD8 MEX3B ARHGAP33 CBX2	7.30e-04	843	50	8	gudmap_developingGonad_e11.5_testes_1000
CoexpressionAtlas	DevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000	NOLC1 BRD2 PNN JMJD6 ACIN1 CHD8 MEX3B CBX2	7.35e-04	844	50	8	gudmap_developingGonad_e11.5_testes and mesonephros_1000
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FAM133B PNN KMT2A ACIN1 SRRM2 PRDM2	1.09e-07	200	51	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	FAM133B PNN JMJD6 CIR1 SRRM2	3.05e-06	197	51	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAM133B PNN JMJD6 CIR1 SRRM2	3.13e-06	198	51	5	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM133B PNN JMJD6 CIR1 SRRM2	3.13e-06	198	51	5	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|megakaryocytic / Lineage and Cell class	ARL6IP4 FAM133B PNN RNPS1 SRRM2	3.21e-06	199	51	5	99a65887d3c8a2cde26693dd74404b101bba9d58
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	FAM133B BRD2 PNN CIR1 SRRM2	3.28e-06	200	51	5	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FAM133B PNN CIR1 SPEN	2.84e-05	153	51	4	88ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-MEMP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BRDT FAM133A NAP1L3 NRG2	2.84e-05	153	51	4	14753baa9980f75206fefc3c8b43685fd4178a43
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FAM133B PNN CIR1 SPEN	2.84e-05	153	51	4	553dff9688a1996d8f4ba16e60c683593d781389
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NAP1L3 MLLT3 MEX3B CBX2	3.22e-05	158	51	4	4f3ea658e032555c2098d016475381c8d1071699
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	FAM133A ZBTB4 NAP1L3 KMT2A	5.01e-05	177	51	4	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	BRD2 JMJD6 NAF1 CIR1	6.07e-05	186	51	4	35f32fc2761435356c8f54b5bb2f026b8c070efe
ToppCell	hematopoetic_progenitors-CD34+_HSC\|World / Lineage and Cell class	FAM133A NAP1L3 MLLT3 CBX2	6.46e-05	189	51	4	51ff31c9cf5eff98ad01c0455dc4ae4908713575
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	FAM133B JMJD6 CIR1 SRRM2	7.01e-05	193	51	4	7256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCell	10x3'2.3-week_17-19\|World / cell types per 3 fetal stages;per 3',per 5'	FAM133B BRD2 SRRM2 PRDM2	7.58e-05	197	51	4	f5cfad0b42d0f817e22cc78b9bfb2b4b7e4330ed
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FAM133B PNN KMT2A MLLT3	7.58e-05	197	51	4	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAM133B BRD2 PNN PRDM2	7.73e-05	198	51	4	5f465cf5c7493e32d9afe9e9d05757d0a95acc33
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FAM133B BRD2 PNN PRDM2	7.73e-05	198	51	4	77ce3fe1ab161c0faf8987e73a64ab61294b9255
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HEG1 DACH1 SHE CBX2	7.89e-05	199	51	4	9735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	PNN KMT2A SRRM2 PRDM2	8.04e-05	200	51	4	7dec470c379cd89f05a0f37c8628b21f136e52f0
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	ING3 PPRC1 CHD9 PRDM2 PHLPP2	5.67e-05	184	51	5	2321_DN
Drug	tyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA	KMT2A CHD9 SPEN PRDM2 PHLPP2	5.82e-05	185	51	5	1114_DN
Drug	Neostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	NOLC1 MBTPS2 KMT2A SPEN PRDM2	6.28e-05	188	51	5	6735_DN
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	KMT2A CHD9 MLLT3 SPEN PRDM2	6.28e-05	188	51	5	4845_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	NOLC1 ING3 JMJD6 SRRM2 SPEN	6.44e-05	189	51	5	1045_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	NOLC1 RANBP10 JMJD6 MLLT3 E2F4	6.61e-05	190	51	5	5218_DN
Drug	Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A	NOLC1 ATN1 KMT2A SPEN PRDM2	6.61e-05	190	51	5	4322_DN
Drug	Solasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A	KCNMA1 DACH1 NRG2 KMT2A CBX2	6.77e-05	191	51	5	3830_UP
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A	NOLC1 ATN1 E2F4 SPEN PRDM2	7.11e-05	193	51	5	4321_DN
Drug	Droperidol [548-73-2]; Down 200; 10.6uM; HL60; HT_HG-U133A	FAM193B DACH1 E2F4 EDC4 CLASRP	7.47e-05	195	51	5	1290_DN
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A	SETD1A HEG1 ATN1 NRG2 ARHGAP33	7.47e-05	195	51	5	4326_DN
Drug	Domperidone maleate; Down 200; 7.4uM; HL60; HT_HG-U133A	DACH1 KMT2A E2F4 EDC4 PRDM2	7.65e-05	196	51	5	1301_DN
Drug	Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; HL60; HG-U133A	RANBP10 PPRC1 NFE2L1 E2F4 PHLPP2	7.84e-05	197	51	5	1385_UP
Drug	Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; MCF7; HT_HG-U133A	HEG1 DACH1 E2F4 ARHGAP33 PHLPP2	7.84e-05	197	51	5	2233_DN
Drug	Azathioprine [446-86-6]; Up 200; 14.4uM; PC3; HT_HG-U133A	SETD1A MBTPS2 MLLT3 E2F4 SRRM2	8.03e-05	198	51	5	4667_UP
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A	SETD1A ATN1 JMJD6 DACH1 SPEN	8.03e-05	198	51	5	4762_DN
Drug	Propidium iodide [25535-16-4]; Down 200; 6uM; MCF7; HT_HG-U133A	SETD1A DACH1 NRG2 E2F4 ARHGAP33	8.03e-05	198	51	5	6104_DN
Drug	dopamine hydrochloride; Down 200; 1uM; MCF7; HG-U133A	RANBP10 SETD1A ACIN1 CHD9 PRDM2	8.22e-05	199	51	5	491_DN
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD8	5.88e-05	7	50	2	DOID:0050834 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	KMT2A CHD9 CHD8	2.22e-04	69	50	3	DOID:1682 (implicated_via_orthology)
Disease	Intellectual Disability	SETD1A ATN1 RLIM ACIN1 CHD8	9.43e-04	447	50	5	C3714756
Disease	triacylglycerol 52:5 measurement	DACH1 MLLT3	1.62e-03	35	50	2	EFO_0010417
Disease	Mitral valve prolapse	MEIOSIN TMEM40	1.71e-03	36	50	2	HP_0001634
Disease	Gastric Adenocarcinoma	BRD2 BRDT	2.66e-03	45	50	2	C0278701
Disease	hepatocellular carcinoma (implicated_via_orthology)	ING3 NFE2L1	3.15e-03	49	50	2	DOID:684 (implicated_via_orthology)
Disease	S-6-hydroxywarfarin measurement	ING3 KMT2A CHD9 MLLT3	3.49e-03	368	50	4	EFO_0803326

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSSSRSSSSSSSSSR	ACIN1	576	Q9UKV3
SSSSSSSSSRSRSRS	ACIN1	581	Q9UKV3
SSSSSSSSSSSSSST	CHD8	2081	Q9HCK8
SSSSSSSSESESSSS	BRDT	641	Q58F21
SSSSSSSSSSSSSSS	MLLT3	151	P42568
SSSSSSSSSSSSSSS	MLLT3	156	P42568
SSSSSSSSSSSSSSS	MLLT3	161	P42568
SSSSSSSSSSSSSSS	MLLT3	166	P42568
SSSSSSSSSSSSSSS	MLLT3	171	P42568
SSSSSSSSSSSSSSS	MLLT3	176	P42568
SSSSSSSSSSTSFSK	MLLT3	181	P42568
SSSSSSSAAASSSSS	ATN1	376	P54259
SSAAASSSSSSSSSS	ATN1	381	P54259
ASTGSSSSSSSSSSS	DACH1	136	Q9UI36
SSSSSSSSSSSSSSS	DACH1	141	Q9UI36
SSSSSSSSSSSSSSS	DACH1	146	Q9UI36
SSSSSSSSSSSSSCG	DACH1	151	Q9UI36
SSSEGSSSSSSSSSS	NFE2L1	491	Q14494
SSSSSSSSSSSSSSA	NFE2L1	496	Q14494
SSSSSSSSSASSSAS	NFE2L1	501	Q14494
SSSSSSSSSSSSPSS	RANBP10	411	Q6VN20
SSSSSSSSSSSSDDS	NOLC1	216	Q14978
SSGSSSSSSSSSSSL	EDC4	616	Q6P2E9
DSSSDSSSSSSSSSS	JMJD6	341	Q6NYC1
SCRSSSSSSSSDSSS	FAM133A	101	Q8N9E0
SSSSSSDSSSSSSDS	FAM133A	106	Q8N9E0
SSSSSSSSSSSSSSS	KCNMA1	41	Q12791
SSSSSSSSSSSSSSS	KCNMA1	46	Q12791
SSSSSSLSSCSSSST	ING3	316	Q9NXR8
SKSRSRSSSSSSSSS	PNN	571	Q9H307
RSSSSSSSSSSSTSS	PNN	576	Q9H307
SSSSSSSTSSSSGSS	PNN	581	Q9H307
SSTSSSSGSSSSSGS	PNN	586	Q9H307
SSSGSSSSRSSSSSS	PNN	596	Q9H307
SSSRSSSSSSSSTSG	PNN	601	Q9H307
SASSDSSSSSSSSSS	CSNKA2IP	631	A0A1B0GTH6
SSSSSSSSSSFSISS	CSNKA2IP	636	A0A1B0GTH6
SSSSSERSSSSSSSS	NRG2	26	O14511
VSDSSSSSSSSSSSS	HEG1	656	Q9ULI3
SSSTSSTSSTSSSST	OLIG1	46	Q8TAK6
APSSSSSSSSSSSSS	MEIOSIN	451	C9JSJ3
HSSSSSSSSSTSSSA	HSPB7	16	Q9UBY9
SSSSESSSSESSSSS	ARHGAP33	681	O14559
SSCSSRSSSSSSSSS	CHD9	2141	Q3L8U1
SSSSSCSSASSSSSS	CHD9	2166	Q3L8U1
CSSASSSSSSSTSSS	CHD9	2171	Q3L8U1
SSSSSSTSSSSSSSS	CHD9	2176	Q3L8U1
SSSSSSSSTSSSSSS	CBX2	106	Q14781
DSSSSSSSSSSSSSN	E2F4	306	Q16254
SSSSSSSSSNSNSSS	E2F4	311	Q16254
SSSSSSSDSSSSSSD	FAM133B	106	Q5BKY9
SSSSSSSSSSSSSSS	FAM193B	171	Q96PV7
RTRSSSSSSSSSSSS	ARL6IP4	71	Q66PJ3
SSSSSSSSSSSSSSS	ARL6IP4	76	Q66PJ3
SSSSSSSSSSSSSSS	ARL6IP4	81	Q66PJ3
SSSSSSSSSSSSSDG	ARL6IP4	86	Q66PJ3
SSYSSSSSSSSSSSS	MBTPS2	111	O43462
SSSSSSSSSSSSSSS	MBTPS2	116	O43462
SSSSSSSSSSSSSSS	MBTPS2	121	O43462
SSSASSSSSSSSSAS	KMT2A	86	Q03164
SSSSSSSSSSSRSRS	PPRC1	1441	Q5VV67
SRRCSSSSSSSSSSS	PPRC1	1476	Q5VV67
SSSSSSSSSSSSSSS	PPRC1	1481	Q5VV67
SSSSSSSSSSSSSSR	PPRC1	1486	Q5VV67
SSSSSSSSSRSRSRS	PPRC1	1491	Q5VV67
LSSSSSSSSSSSSFS	PRDM2	1051	Q13029
SSSSSSSSFSSSSSS	PRDM2	1056	Q13029
SGSSSSSSSSSSSSS	MEX3B	491	Q6ZN04
SSSSSSSSSSSSSGL	MEX3B	496	Q6ZN04
SGSSSTSRSSSSSSS	RNPS1	106	Q15287
RSSSSSSSSSSSSSS	SRRM2	2531	Q9UQ35
SSSSSSSSSSSSSSS	SRRM2	2536	Q9UQ35
SSSSSSSSSSSSSSS	SRRM2	2541	Q9UQ35
SSSSSSSSSSSGSSS	SRRM2	2546	Q9UQ35
RSSSSSSSSSSSSSS	SRRM2	2606	Q9UQ35
SSSSSSSSSSSSSSS	SRRM2	2611	Q9UQ35
SSSSSSSSSSSSSSS	SRRM2	2616	Q9UQ35
SSSSSSSSSSSSSSS	SRRM2	2621	Q9UQ35
SSSSSSSSSSSSSSS	SRRM2	2626	Q9UQ35
SSSSSSSSSSSSSSS	SRRM2	2631	Q9UQ35
SSSSSSSSSSSSSPS	SRRM2	2636	Q9UQ35
SGSSSSSSSSASASS	NKX6-1	121	P78426
SSSSSSTSDSSSSSS	NAP1L3	36	Q99457
STSDSSSSSSTSGSS	NAP1L3	41	Q99457
SSSASSSSLSSSSSS	SETD1A	336	O15047
SSSLSSSSSSSSSSS	SETD1A	341	O15047
SSSSSSSSSSSSQFR	SETD1A	346	O15047
SDSESSSSSSSSSSS	SETD1A	1031	O15047
SSSSSSSSSSSSSSS	SETD1A	1036	O15047
SSSSSSSSSSSSSSS	SETD1A	1041	O15047
SSSSSSSSSSSSSES	SETD1A	1046	O15047
ASSSSSDSSSSSSSS	BRD2	776	P25440
SDSSSSSSSSSSSDT	BRD2	781	P25440
KSSSSSSSSSSSSSS	CIR1	256	Q86X95
RSSSSSSSSSASRTS	CLASRP	376	Q8N2M8
SSSSSASRTSSSRSS	CLASRP	381	Q8N2M8
SSSSSGSSSSSSSSS	TNRC18	2561	O15417
SPASSSSSSSSSSSS	TNRC18	2611	O15417
SSSSSSSSSSSSSSS	TNRC18	2616	O15417
SSSSSSSSSSSSSSS	TNRC18	2621	O15417
SSSSSSSSSSSSSSS	TNRC18	2626	O15417
SSSSSSSSSSSSSSS	TNRC18	2631	O15417
SSSSSSSSSSSSSSS	TNRC18	2636	O15417
SSSSSSSSSSSSSSS	TNRC18	2641	O15417
SSSSSSSSSSSSSSS	TNRC18	2646	O15417
SSSSSSSSSSSSSSS	TNRC18	2651	O15417
SSSSSSSSSSSSSSS	TNRC18	2656	O15417
SSSSSSSSSSSSSSS	ZNF865	96	P0CJ78
SSSSSSSSSSSSSSS	ZNF865	101	P0CJ78
SSSSTSSDSSDSSSS	SPEN	286	Q96T58
TTTTSSSSSSSSSSS	PHLPP2	46	Q6ZVD8
GSSSSSSSSSSSSSS	RLIM	456	Q9NVW2
SSSSSSSSSSSSSSS	RLIM	461	Q9NVW2
SSSSSSSSSSSPSSS	RLIM	466	Q9NVW2
SSSSSSSSSSSSSSS	TMEM40	51	Q8WWA1
SSSSSSSSSSSSSSS	TMEM40	56	Q8WWA1
TTAASSSSSSSSSSS	ZBTB4	81	Q9P1Z0
SSSSSSSSSSSSSSS	ZBTB4	86	Q9P1Z0
SSSSSSSSSSASSSS	ZBTB4	91	Q9P1Z0
SSSSSASSSSSSSSS	ZBTB4	96	Q9P1Z0
SSSTSSPSSSSSSSS	TPRXL	86	Q17RH7
SSSSSSSPSSSSSSS	TPRXL	111	Q17RH7
SSSSSSSSPSSSSSS	TPRXL	121	Q17RH7
SSSSSPSSSSSSSSS	TPRXL	131	Q17RH7
SSSPSSSSSSSSSSS	TPRXL	151	Q17RH7
SSSSSSSSSSSSPSS	TPRXL	156	Q17RH7
SSSSSSASSTTSSSS	ZCCHC10	146	Q8TBK6
DSSSSSSSSTSTDSS	ZCCHC10	166	Q8TBK6
SSSSSSSSSASSSPS	SHE	166	Q5VZ18
SDSSSSSSSSSSSSS	NAF1	126	Q96HR8
SSSSSSSSSSSSSSS	NAF1	131	Q96HR8