Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Pubmed

Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.

FAM90A17 FAM90A19 FAM90A18 FAM90A9 FAM90A8 FAM90A16

1.17e-0925155617684299
Pubmed

Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.

FAM90A17 FAM90A19 FAM90A9 FAM90A8 FAM90A16

5.20e-0823155518602769
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TOM1L2 CARMIL2 RCHY1 HNRNPM BRSK2 PFKM GRM2 HNRNPC NDUFS2 MYEF2 SPTBN4 MAGI2 PARP1 MYH14 SV2A HECW2 TLN1 GNAI1 BRSK1 FLOT1 PC DAGLA

4.26e-0714311552237142655
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TOM1L2 HK2 MAGED1 JAGN1 HNRNPM SRPRB RNF43 NDUFS2 URGCP GTF3C3 ARHGEF40 TLN1 PVR UBAC2 ATIC ZNF598 SLC27A4

1.16e-069421551731073040
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

MAGED1 JAGN1 SMC6 HNRNPM ATL3 LAMB2 SRPRB HNRNPC GTF3C3 PARP1 SV2A SLC5A6 PVR RBM7 UBAC2 FLOT1 ABHD16A SLC27A4 AGTRAP

1.90e-0612031551929180619
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

TOM1L2 CTSF HK2 PIWIL1 BRSK2 LAMB2 SRPRB RGS12 SLC5A6 PIGO DCAF7

6.14e-064501551116751776
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

JAGN1 HNRNPM ATL3 LAMB2 RNF213 PFKM SRPRB NDUFS2 RHOC MAGI2 GCAT TLN1 ISCU PVR CPSF1 SLC9A6 ABHD16A PIGO SLC27A4 DCAF7

7.67e-0614511552030550785
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MPP3 ARHGEF19 MYO9B SHISA5 LAMB2 PAPLN BIRC6 SH2B2 RNF43 KANSL3 ARHGEF40 TLN1 CPSF1 ZNF324B PC ARHGAP33 AGTRAP

9.64e-0611051551735748872
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HK2 MYO9B HNRNPM ATL3 PFKM BIRC6 SRPRB HNRNPC GTF3C3 MYEF2 PARP1 ARHGEF40 MYH14 PIN1 TLN1 RBM7 CPSF1 ATIC SLC27A4

1.02e-0513531551929467282
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

MPP3 DPP10 GRM2 GPR162 RGS12 SV2A HGS GNAI1 FLOT1 DAGLA

1.51e-054051551038187761
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

TOM1L2 HTRA2 RCHY1 RNF213 BIRC6 NDUFS2 GTF3C3 GCAT HGS CPSF1 UBAC2 KIF22

1.84e-056041551238803224
Pubmed

Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network.

SLC9A7 SLC9A6

1.97e-052155211279194
Pubmed

Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.

BRSK2 BRSK1

1.97e-052155230307479
Pubmed

DNA polymerase beta and PARP activities in base excision repair in living cells.

POLB PARP1

1.97e-052155219748837
Pubmed

A membrane-proximal region in the C-terminal tail of NHE7 is required for its distribution in the trans-Golgi network, distinct from NHE6 localization at endosomes.

SLC9A7 SLC9A6

1.97e-052155220364249
Pubmed

SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release.

BRSK2 BRSK1

1.97e-052155216630837
Pubmed

Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation.

BRSK2 BRSK1

1.97e-052155218339622
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNHD1 HK2 HTRA2 SMC6 HNRNPM PFKM SRPRB HNRNPC NDUFS2 GTF3C3 PARP1 MYH14 TLN1 CPSF1 ATIC FLOT1 PC SLC27A4 DCAF7

2.09e-0514251551930948266
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

MAGED1 HNRNPM DNPH1 GFER HNRNPC GTF3C3 PARP1 MYH14 GNAI1 ATIC ZNF598 PC

2.53e-056241551233729478
Pubmed

Comparative analyses of the Dominant megacolon-SOX10 genomic interval in mouse and human.

GALR3 DMC1 GCAT

3.05e-0514155310384052
Pubmed

Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.

ACO1 PDYN MON1B

3.05e-0514155324811271
Pubmed

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

MAGED1 HTRA2 NDUFS2 SETDB1 GCAT UBAC2 SLC27A4

4.49e-05209155726389662
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

HNRNPM PFKM SRPRB HNRNPC NDUFS2 PARP1 MYH14 UBAC2 PC PGM2 SLC27A4

4.97e-055651551133567341
Pubmed

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria.

ACO1 SLC25A37

5.90e-053155224509859
Pubmed

Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit.

RCHY1 SRPRB

5.90e-053155218344599
Pubmed

Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells.

BRSK2 BRSK1

5.90e-053155222669945
Pubmed

Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly.

ACO1 ISCU

5.90e-053155216527810
Pubmed

ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.

ACO1 SLC25A37

5.90e-053155235121990
Pubmed

Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity.

POLB PARP1

5.90e-053155215731342
Pubmed

Replication of genetic variation in the MYO9B gene in Crohn's disease.

MYO9B MAGI2

5.90e-053155221515326
Pubmed

The Role of Pentraxin-3, Fetuin-A and Sirtuin-7 in the Diagnosis of Prostate Cancer.

SIRT7 PTX3

5.90e-053155234655076
Pubmed

Intestinal barrier gene variants may not explain the increased levels of antigliadin antibodies, suggesting other mechanisms than altered permeability.

MYO9B MAGI2

5.90e-053155220096742
Pubmed

Pin1-mediated Modification Prolongs the Nuclear Retention of β-Catenin in Wnt3a-induced Osteoblast Differentiation.

PIN1 WNT3A

5.90e-053155226740630
Pubmed

Comparative expression analysis of the MAGED genes during embryogenesis and brain development.

MAGED1 TRO

5.90e-053155215162511
Pubmed

Neuroimaging, nutrition, and iron-related genes.

ACO1 TFR2

5.90e-053155223817740
Pubmed

Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity.

BRSK2 BRSK1

5.90e-053155220026642
Pubmed

Microtubule stabilization specifies initial neuronal polarization.

BRSK2 BRSK1

5.90e-053155218268107
Pubmed

Overexpression of Pin1 and rho signaling partners correlates with metastatic behavior and poor recurrence-free survival of hepatocellular carcinoma patients.

RHOC PIN1

5.90e-053155231324164
Pubmed

Expression of HK2, PKM2, and PFKM Is Associated with Metastasis and Late Disease Onset in Breast Cancer Patients.

HK2 PFKM

5.90e-053155235328104
Pubmed

Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure.

POLB PARP1

5.90e-053155215701627
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

HK2 MAGED1 BIRC6 GFER NDUFS2 GTF3C3 ATRIP GCAT FDX1 ISCU CPSF1 UBAC2

6.30e-056861551228380382
Pubmed

Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo.

SFRP5 WNT6 WNT3A

6.74e-0518155322166339
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ACO1 STARD10 HNRNPM HNRNPC MYEF2 RHOC PARP1 MYH14 TLN1 ATIC BRSK1 PC PGM2

7.14e-058071551330575818
Pubmed

Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne.

TOM1L2 HGS OTUD7A UBAC2

7.45e-0550155431699778
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

HK2 MAGED1 ATL3 SRPRB NDUFS2 RHOC GCAT CPSF1 UBAC2 PC DCAF7

9.26e-056061551136538041
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

HK2 HNRNPM LAMB2 PFKM SRPRB HNRNPC NDUFS2 HEPH TFR2 CILP2 GCAT

1.02e-046131551122268729
Pubmed

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.

RNF213 ATIC ZNF598

1.09e-0421155337422473
Pubmed

Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenoma.

POLB PARP1

1.18e-044155217283177
Pubmed

HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells.

HTRA2 BIRC6

1.18e-044155215781261
Pubmed

Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration.

WNT6 WNT3A

1.18e-044155218697834
Pubmed

Transient OGG1, APE1, PARP1 and Polβ expression in an Alzheimer's disease mouse model.

POLB PARP1

1.18e-044155224121118
Pubmed

Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.

TPRN RHOC

1.18e-044155227269051
Pubmed

Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina.

ACO1 HEPH

1.18e-044155215354085
Pubmed

Tuberous sclerosis complex proteins control axon formation.

BRSK2 BRSK1

1.18e-044155218794346
Pubmed

An optimized procedure for whole-mount in situ hybridization on mouse embryos and embryoid bodies.

SFRP5 WNT6

1.18e-044155218600225
Pubmed

Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions.

SLC9A7 SLC9A6

1.18e-044155221171650
Pubmed

RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners.

HNRNPM HNRNPC

1.18e-044155234244793
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

HK2 ATL3 PFKM NDUFS2 PARP1 TLN1 GNAI1 ATIC FLOT1

1.24e-04422155927342126
Pubmed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

HK2 ACO1 PFKM PC PGM2

1.64e-04114155528245920
Pubmed

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

SHISA5 LAMB2 GRM2 SEMA3B

1.73e-0462155419367581
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

CELF6 CELF5 PIWIL1 HNRNPM HNRNPC MYEF2 ADAD2 CPSF1

1.75e-04347155816033648
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

TOM1L2 MAGED1 HNRNPM RNF213 MYH14 GNAI1 FLOT1

1.92e-04264155732814769
Pubmed

Two-color in situ hybridization of whole-mount mouse embryos.

TBX18 WNT3A

1.96e-045155224318811
Pubmed

A role for WNT proteins in induction of dermomyotome.

WNT6 WNT3A

1.96e-04515529356179
Pubmed

Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.

HTRA2 BIRC6

1.96e-045155236758105
Pubmed

Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases.

HTRA2 BIRC6

1.96e-045155236758104
Pubmed

Human SAD1 kinase is involved in UV-induced DNA damage checkpoint function.

BRSK2 BRSK1

1.96e-045155215150265
Pubmed

Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation.

SLC9A7 SLC9A6

1.96e-045155215522866
Pubmed

Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function.

POLB PARP1

1.96e-045155225378300
Pubmed

C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest.

BRSK2 BRSK1

1.96e-045155218854318
Pubmed

p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.

POLB PARP1

1.96e-045155220303835
Pubmed

RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity.

RGS12 GNAI1

1.96e-045155211387333
Pubmed

Decreased PARP-1 levels accelerate embryonic lethality but attenuate neuronal apoptosis in DNA polymerase beta-deficient mice.

POLB PARP1

1.96e-045155217257586
Pubmed

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.

ARHGEF19 SFRP5 RNF43 WNT3A

1.96e-0464155424431302
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

DPP10 HNRNPM PFKM SRPRB HNRNPC MYEF2 RHOC PARP1 MYH14 TLN1 ATIC FLOT1

2.71e-048031551236517590
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

HK2 HTRA2 ACO1 GFER NDUFS2 SLC25A37 TATDN3 PSTK GCAT FDX1 ISCU ATIC PC

2.75e-049261551320877624
Pubmed

LKB1 and AMPK regulate synaptic remodeling in old age.

BRSK2 BRSK1

2.93e-046155225086610
Pubmed

Mammalian SAD kinases are required for neuronal polarization.

BRSK2 BRSK1

2.93e-046155215705853
Pubmed

Phosphorylation of microtubule-associated protein tau by AMPK-related kinases.

BRSK2 BRSK1

2.93e-046155221985311
Pubmed

Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3.

NAA80 SEMA3B

2.93e-046155211929860
Pubmed

SAD kinases control the maturation of nerve terminals in the mammalian peripheral and central nervous systems.

BRSK2 BRSK1

2.93e-046155224395778
Pubmed

Involvement of p114-RhoGEF and Lfc in Wnt-3a- and dishevelled-induced RhoA activation and neurite retraction in N1E-115 mouse neuroblastoma cells.

ARHGEF19 WNT3A

2.93e-046155220810787
Pubmed

Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties.

WNT6 WNT3A

2.93e-04615527556445
Pubmed

A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.

CELF6 CELF5

2.93e-046155210893231
Pubmed

Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function.

HTRA2 BIRC6

2.93e-046155215300255
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

MAGED1 JAGN1 TRO ACO1 SMC6 HNRNPM RNF213 NDUFS2 MYEF2 ANGPT4 PVR PC ABHD16A PIGO

3.00e-0410611551433845483
Pubmed

Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.

SFRP5 WNT6 WNT3A

3.23e-0430155315880404
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

TRHDE TOM1L2 ACO1 HNRNPM LAMB2 DNPH1 SPTBN4 CILP2 CLN5 TLN1 ATIC FLOT1 PGM2 ALOX15B

3.26e-0410701551423533145
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

HNRNPM ATL3 PARP1 SLC5A6 TLN1 PVR HGS FLOT1 PC

3.41e-04484155931995728
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

DNHD1 RNF213 PFKM PARP1 ANGPT4 TLN1

3.55e-04208155633230847
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

TOM1L2 HK2 HTRA2 RNF213 PFKM BIRC6 SRPRB HNRNPC NDUFS2 PARP1 FDX1 ISCU RBM7 CPSF1 UBAC2 ZNF598 FLOT1

3.87e-0414961551732877691
Pubmed

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

HK2 HGSNAT MON1B SRPRB UBAC2 FLOT1 PC AGTRAP

3.96e-04392155833144569
Pubmed

Pol β associated complex and base excision repair factors in mouse fibroblasts.

POLB PARP1

4.08e-047155223042675
Pubmed

DLX5, FGF8 and the Pin1 isomerase control ΔNp63α protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations.

PIN1 WNT3A

4.08e-047155224569166
Pubmed

Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation.

SIRT7 PARP1

4.08e-047155230166529
Pubmed

Nerve growth factor stimulates the concentration of TrkA within lipid rafts and extracellular signal-regulated kinase activation through c-Cbl-associated protein.

SH2B2 FLOT1

4.08e-047155217548467
Pubmed

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.

SETDB1 PARP1

4.08e-047155221983785
Pubmed

MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors.

MAGED1 ARNT2

4.08e-047155227472814
Pubmed

Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo.

HGS FLOT1

4.08e-047155228581508
Pubmed

Taperin (c9orf75), a mutated gene in nonsyndromic deafness, encodes a vertebrate specific, nuclear localized protein phosphatase one alpha (PP1α) docking protein.

TPRN PARP1

4.08e-047155223213405
Cytoband8p23.1

FAM90A17 FAM90A19 FAM90A18 FAM90A9 FAM90A8 FAM90A16

1.50e-0515415568p23.1
CytobandEnsembl 112 genes in cytogenetic band chr3p21

SHISA5 LAMB2 NAA80 GRM2 ATRIP SEMA3B KLHDC8B

1.07e-043161557chr3p21
CytobandEnsembl 112 genes in cytogenetic band chr8p23

FAM90A17 FAM90A19 FAM90A18 FAM90A9 FAM90A8 FAM90A16

1.53e-042341556chr8p23
Cytoband22q13.1

GALR3 APOL1 DMC1 GCAT

2.05e-0485155422q13.1
Cytoband7q21

MAGI2 GNAI1

8.62e-041315527q21
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#2

MAGED1 POLB ATL3 DNPH1 NDUFS2 SLC25A37 KANSL3 SETDB1 ARHGEF40 GCAT PVR HGS ABHD16A DCAF7

1.51e-0552514514Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K2
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF19 SFRP5 WNT6 PIWIL1 STARD10 MYH14 SEMA3B

3.07e-061841507a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

TRHDE HK2 ACO1 GNAI1 PNPLA3 PC

2.12e-0516615067e5852891714465c6228c9f955fd511ec79d0e02
ToppCellLV-11._Adipocyte|LV / Chamber and Cluster_Paper

TRHDE HK2 ACO1 GNAI1 PNPLA3 PC

2.68e-051731506c2d3fcb3de71015d03d14c63450853d2b03ffa71
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPLN RNF43 HECW2 CLN5 PC ALOX15B

2.86e-0517515061b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPLN RNF43 HECW2 CLN5 PC ALOX15B

2.86e-051751506a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

TRHDE HK2 ACO1 GNAI1 PNPLA3 PC

3.05e-051771506f0edf04930692418953e4f00a917257804ec0ffd
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

TRHDE HK2 ACO1 GNAI1 PNPLA3 PC

3.15e-051781506278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPP3 SLC13A2 RNF43 MAST4 MYH14 SLC22A31

3.25e-051791506fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

WNT6 PAPLN COL22A1 XPNPEP2 DMC1

3.26e-051081505db82e0273ce10627462ff0402f4c1d4c9cb3875b
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

WNT6 PAPLN COL22A1 XPNPEP2 DMC1

3.26e-0510815052a00a9d3c9ef0c9c743939ee6e79ccbd401eccf7
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

WNT6 PAPLN COL22A1 XPNPEP2 DMC1

3.26e-0510815050c8bac6c520a3600765327c44705675927bc2f60
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

MPP3 RGS12 RHOC TBX18 GNAI1 FUT7

3.35e-051801506289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCellHSPCs-Erythroblasts|World / Lineage and Cell class

STARD10 PFKM SLC25A37 RGS12 TFR2 KIF22

3.45e-051811506ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

TRHDE HK2 DPP10 ACO1 PNPLA3 PC

3.67e-051831506b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

TRHDE HK2 DPP10 ACO1 PNPLA3 PC

3.67e-0518315063f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPP3 SLC13A2 SRPRB RNF43 MYH14 SLC22A31

3.90e-051851506fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPP3 SLC13A2 RNF43 MAST4 MYH14 SLC22A31

4.02e-051861506e83718fabb057100835d3357df407f283d23fe16
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP5 WNT6 PIWIL1 STARD10 MYH14 SEMA3B

4.27e-0518815068385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPP3 SLC13A2 RNF43 MAST4 MYH14 SLC22A31

4.27e-0518815064bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP5 WNT6 PIWIL1 STARD10 MYH14 SEMA3B

4.27e-051881506cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCellC_05|World / shred on cell type and cluster

HK2 RNF213 APOL1 TYMP GFER RHOC

5.38e-051961506bf4dfb460a153dbafb2b9b12b360c8757cec22cd
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MPP3 MROH5 RNF43 MYH14 PVR SLC22A31

5.53e-051971506b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellControl_saline-Epithelial_alveolar-AT_2|Control_saline / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.53e-051971506b8f62fcd6eb8f47b3cc41f616126f82c68a36e87
ToppCellControl_saline-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|Control_saline / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.69e-051981506030ef63e2fc5b3d601c1a48462d797aa19ee7ff5
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.69e-05198150653e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.69e-05198150682bcd44f8744e7e8477fbfd871a52f3d1a8b3adc
ToppCellLPS_only-Epithelial_alveolar-AT_1-2_Progenitor|LPS_only / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.85e-0519915063a0af1a13b1760f4213d87d0958dbe3bf3b9a42b
ToppCellLPS_IL1RA-Epithelial_alveolar|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.85e-0519915065b140ac88ebc25ce397ae577e48f3e271faf46e7
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSF HK2 COL22A1 CILP2 SEMA3B GNAI1

5.85e-051991506edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.85e-051991506bb2e839197b9a44b632c1bb716e48d885a1c8713
ToppCellLPS_only-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2|LPS_only / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.85e-0519915060447f8f53389fe7c6ddc04a97d86e74122ea16f4
ToppCellLPS_only-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_only / Treatment groups by lineage, cell group, cell type

MPP3 STARD10 SLC13A2 RNF43 MYH14 SLC22A31

5.85e-0519915067b21447bb39cdba37539a12cb475f463010fc23f
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TPRN HEPH SPTBN4 GCAT ZNF324B

6.80e-05126150510e1448a03f79965b72922fd83ef51de1b7b474f
Diseaseserine/threonine-protein kinase BRSK2 measurement

BRSK2 BRSK1

7.57e-0531492EFO_0803063
Diseaseobsolete_red blood cell distribution width

MPP3 TSR2 CARMIL2 MYO9B SHISA5 PAPLN TYMP BIRC6 GFER SLC25A37 TFR2 C9orf153 CILP2 MAST4 HECW2 PNPLA3 DAGLA SLC22A31

1.61e-04134714918EFO_0005192
DiseaseAutosomal Dominant Parkinsonism

HTRA2 PDYN PARP1

3.77e-04281493C0752098
DiseaseAutosomal Dominant Juvenile Parkinson Disease

HTRA2 PDYN PARP1

3.77e-04281493C0752097
DiseaseParkinsonism, Experimental

HTRA2 PDYN PARP1

3.77e-04281493C0752101
DiseaseAutosomal Recessive Parkinsonism

HTRA2 PDYN PARP1

3.77e-04281493C0752100
DiseaseFamilial Juvenile Parkinsonism

HTRA2 PDYN PARP1

3.77e-04281493C0752104
DiseaseRamsay Hunt Paralysis Syndrome

HTRA2 PDYN PARP1

3.77e-04281493C0242423
DiseasePARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE

HTRA2 PDYN PARP1

3.77e-04281493C1868675
DiseaseParkinsonism, Juvenile

HTRA2 PDYN PARP1

4.64e-04301493C0752105
DiseaseParkinsonian Disorders

HTRA2 PDYN PARP1

4.64e-04301493C0242422
DiseaseX-23641 measurement

PSTK PNPLA3

5.23e-0471492EFO_0800854
Diseasemembrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 measurement

MAGI2 GNAI1

6.95e-0481492EFO_0802739
Diseasethioredoxin domain-containing protein 12 measurement

SHISA5 NAA80 GRM2

1.01e-03391493EFO_0008298
Diseasehepatocellular carcinoma

HNRNPC WNT3A PNPLA3

1.17e-03411493EFO_0000182
Diseasecryptorchidism (biomarker_via_orthology)

HTRA2 GFER

1.35e-03111492DOID:11383 (biomarker_via_orthology)
Diseasestomach carcinoma (is_implicated_in)

RNF43 PARP1

1.62e-03121492DOID:5517 (is_implicated_in)
DiseaseRespiratory Depression

CACNA1S PDYN

1.90e-03131492C0235063
DiseaseRespiratory Insufficiency

CACNA1S PDYN

1.90e-03131492C0035229
DiseaseRespiratory Failure

CACNA1S PDYN

1.90e-03131492C1145670
Diseasetyrosine-protein phosphatase non-receptor type 1 measurement

PDYN HNRNPC

1.90e-03131492EFO_0020834
Diseasedecreased susceptibility to hepatitis C infection

COL22A1 PSTK

2.90e-03161492EFO_0010101
Diseasefocal segmental glomerulosclerosis

APOL1 PPCS

2.90e-03161492EFO_0004236
DiseaseEndometrial Neoplasms

RNF43 MLH3 SEMA3B

3.18e-03581493C0014170
DiseaseTactile Amnesia

PDYN GNAI1

3.28e-03171492C0750906
DiseaseAmnestic State

PDYN GNAI1

3.28e-03171492C0750907
DiseaseDissociative Amnesia

PDYN GNAI1

3.28e-03171492C0236795
DiseaseHysterical amnesia

PDYN GNAI1

3.28e-03171492C0233750
DiseaseTemporary Amnesia

PDYN GNAI1

3.28e-03171492C0233796
DiseaseAmnesia

PDYN GNAI1

3.28e-03171492C0002622
DiseaseGlobal Amnesia

PDYN GNAI1

3.28e-03171492C0262497
Diseaseprion disease

RCHY1 ATRIP

4.09e-03191492EFO_0004720
Diseaseblood lead measurement

MON1B MAGI2 TBX18

4.58e-03661493EFO_0007040
DiseaseNeutropenia

HTRA2 JAGN1

4.99e-03211492C0027947

Protein segments in the cluster

PeptideGeneStartEntry
MGEDDAALRAGSRGL

TRHDE

1

Q9UKU6
SRRGNDAVMARGTFA

ACO1

711

P21399
MASASQGADDDGSRR

ADAD2

1

Q8NCV1
AGTFQEMRALALDLG

ARHGEF40

916

Q8TER5
GTRIERDDAMSSFGV

BIRC6

1576

Q9NR09
VLSAMIRGAADGSRF

DNPH1

126

O43598
MAAAGGARLLRAASA

FDX1

1

P10109
MRALGRALATNAAFD

CARMIL2

321

Q6F5E8
VGRAMSRAAFEGVVR

GRM2

241

Q14416
GEDMSADGRRQLALF

ABHD16A

516

O95870
AGAKAISSDMFFGRE

ARFGAP2

426

Q8N6H7
AELTLLGAGMRDAFQ

DNHD1

1836

Q96M86
MALFRVDFSGRGELA

DMC1

226

Q14565
ASEGRGEDRKLFVGM

CELF6

126

Q96J87
AFSRAGGGRDMFASV

DCAF7

181

P61962
MDNVIVARFDGRGSG

DPP10

591

Q8N608
SFGRRLGQALLDSMD

ANKRD19P

6

Q9H560
ARGGKRRSGMDFDDE

ARNT2

41

Q9HBZ2
RAMGRLKIDFGDSAR

GNAI1

86

P63096
ESAILDRVADGMVFG

PARP1

276

P09874
MAAAGAFRLRRAASA

ISCU

1

Q9H1K1
ALGAMRALGEAASFS

MON1B

376

Q7L1V2
TGAAREGKASGMEAR

ARHGEF19

226

Q8IW93
GGLIMFSRASRADDG

HECW2

486

Q9P2P5
RNARAAVAGEDGRMI

HNRNPC

61

P07910
MEERERGARSAGAGS

LSM11

1

P83369
ARAEARTRMGIGDEA

MAGED1

686

Q9Y5V3
AVIAMGSADRDGRLH

MAGI2

806

Q86UL8
GNTVRDDGARSMAEA

NLRC3

731

Q7RTR2
GTDGSDFQHRERVAM

JAGN1

11

Q8N5M9
MARGGAGAEEASLRS

GPR162

1

Q16538
GFGRRLMEGLEVFAR

NAA80

151

Q93015
LMEGLEVFARARGFR

NAA80

156

Q93015
EMSRGLLAVRGAFVG

GPR137

131

Q96N19
GASFDRAIEMERGNF

HNRNPM

616

P52272
RAIEMERGNFGGSFA

HNRNPM

621

P52272
RIADFGMASLQVGDS

BRSK2

156

Q8IWQ3
IRMNLGGRVDFDDFV

CABP5

76

Q9NP86
RFLRSEDGSGKGAAM

HK2

441

P52789
GMFTTESRLGGARDE

CPSF1

706

Q10570
VRMRGEAEAFAIGAR

FLOT1

316

O75955
LGSRVRAMEAEAAGL

MYH14

1351

Q7Z406
AFNARIGGVRMLDGT

PCSK4

221

Q6UW60
AKARGDLGAFSRGQM

PIN1

116

Q13526
GFRGEALANIADMAS

MLH3

91

Q9UHC1
RREMAAASAAAISGA

KIF22

11

Q14807
GFREGAESELMRDAQ

PDYN

136

P01213
SAFDRILGSRMGVEA

PFKM

306

P08237
LLRDARMLFGASAGA

PNPLA3

36

Q9NST1
DFGSARELAAFLTGM

FUT7

276

Q11130
FGARMEFGTAGLRAA

PGM2

51

Q96G03
VLEMFSGGDAAALER

LAMB2

726

P55268
MAGAERALSSAGERA

LAMB2

1646

P55268
LRLVATDGAFSMDGD

GCAT

196

O75600
VVADTMLRDSGGEAF

OTUD7A

321

Q8TE49
ADRSAAEMSGRGSVL

FAM90A17

166

P0DV74
ADRSAAEMSGRGSVL

FAM90A16

166

P0DV73
ADRSAAEMSGRGSVL

FAM90A19

166

P0DV76
SDGAMRVARAFERGI

IRGC

351

Q6NXR0
MAALRALCGFRGVAA

NDUFS2

1

O75306
EVMARFAARLGAQGR

PPCS

21

Q9HAB8
ADRSAAEMSGRGSVL

FAM90A8

166

A6NJQ4
EAARGARMVALERGG

FJX1

146

Q86VR8
RSGEMDSRGRTVFGA

FCHSD1

71

Q86WN1
VGMGGAAAFREVRVQ

ARHGAP33

481

O14559
GRAGRAMLAVAALYA

GALR3

231

O60755
MAAAGRGREQDSARF

C5orf47

1

Q569G3
GRSADVRQGEFVVAM

HTRA2

246

O43464
AAMEEGIFRRTGGLF

CACNA1S

1591

Q13698
GIDFGDVSSRMALRE

GALNT8

456

Q9NY28
SESRGGRDRKLFVGM

CELF5

126

Q8N6W0
LNVMSFTRGADVRGD

C9orf153

61

Q5TBE3
ALEMFNRGRAAGTRA

CTSF

46

Q9UBX1
ERANASAPAFIMAGE

ANGPT4

271

Q9Y264
MSALFLGVGVRAEEA

APOL1

16

O14791
GAMKDAVRVVFRGSR

COL22A1

341

Q8NFW1
RVAAAASRGADDAME

ATL3

6

Q6DD88
RIADFGMASLQVGDS

BRSK1

171

Q8TDC3
ASVRASEGAMSDGRV

MAST4

1611

O15021
EMVLSQAFGRDLGRG

DAGLA

446

Q9Y4D2
MAHRGGERDFQTSAR

KANSL3

1

Q9P2N6
RRAFAGCAMAEGSVF

KLHDC8B

211

Q8IXV7
DMGRRNAGIDFGSRK

KIAA1210

616

Q9ULL0
RAAERAAGMSGAGRA

HGSNAT

21

Q68CP4
SAEDIFFRRAKEGMG

CACTIN

601

Q8WUQ7
RLSDGDMTSALRGVA

ATRIP

516

Q8WXE1
MEQEARVLRAAGGFG

SLC22A31

1

A6NKX4
FSFGDLKVLDMARAG

SLC13A2

526

Q13183
FRRGAESSGDMDVLL

POLB

181

P06746
MGSAEFEDIRAFLGA

COL6A6

1976

A6NMZ7
DAGRRLARMEGAEAQ

PTX3

126

P26022
SEEGRDMANRISAFG

RHOC

141

P08134
GRANFSGMSERNDLF

SERPINB2

336

P05120
VVARIMRGGAADRSG

MPP3

161

Q13368
FNDERDGIRAAAMAL

MROH5

1131

Q6ZUA9
DGIRAAAMALFGDLV

MROH5

1136

Q6ZUA9
FGDLVAAMADRELSG

MROH5

1146

Q6ZUA9
MAEFRVRVSTGEAFG

ALOX15B

1

O15296
DMTAGRRSIAGFVAS

PIWIL1

636

Q96J94
ASLRMFGLRVEDEGN

PVR

106

P15151
MGAAAAEADRTLFVG

RBM7

1

Q9Y580
MASADSRRVADGGGA

SRPRB

1

Q9Y5M8
AFDGRPSVAMEGVRA

TATDN3

171

Q17R31
SAVAESREERMGGAG

STARD10

266

Q9Y365
GLRGAMAFALAIRDT

SLC9A6

456

Q92581
SRFLMGSARGDKEGD

TMCO3

396

Q6UWJ1
MRAAAAGGGVRTAAL

SFRP5

1

Q5T4F7
SSMERDFGRGDIGIN

MYEF2

411

Q9P2K5
SEARAIMLSRGLAFG

SLC5A6

391

Q9Y289
ADRSAAEMSGRGSVL

FAM90A9

166

A6NNJ1
HGGRSDMDREFALLF

HEPH

911

Q9BQS7
QAVARRMDGDSRDGG

SLC25A37

11

Q9NYZ2
ARMAGERGASAVLFD

RNF43

126

Q68DV7
MNGDDTFARRPTVGA

SSX3

1

Q99909
ARGEVCMASRGLSLF

SHISA5

26

Q8N114
MAAGGLSRSERKAAE

SIRT7

1

Q9NRC8
MEEGFRDRAAFIRGA

SV2A

1

Q7L0J3
EGRAGGSRMEAEKAS

SETDB1

1011

Q15047
GLMGEANIRFARGER

GTF3C3

151

Q9Y5Q9
MMDDLATDARGRGAG

GFER

26

P55789
DTAQGAEMRRGAGAA

CLN5

6

O75503
DGFSREMKADAGTAV

CILP2

1086

Q8IUL8
AQRDSIDAISMFLGG

AGTRAP

46

Q6RW13
AGLGYRVSMEETADR

RNF213

2541

Q63HN8
GMGSFREDSVVLSRA

URGCP

246

Q8TCY9
MAGAAEDARALFRAG

TSR2

1

Q969E8
EGSRERAQGMATLVF

TEX13D

601

A0A0J9YY54
LIEGMRARAFLDGDA

RGS12

396

O14924
EAEARAEARAQMGIG

TRO

656

Q12816
GGDMAVLSEAELSRF

PAPLN

996

O95428
RGLASGDVAAIFMEN

SLC27A4

121

Q6P1M0
KGFRDSGRNRMGLEA

TBX18

326

O95935
ADLMGRDFTIFRSLG

SEMA3B

191

Q13214
REAAEGLRMATNAAA

TLN1

891

Q9Y490
DDVMPDAFLAGARAR

PSTK

56

Q8IV42
MGLTAAGDARDTADA

SPAG16

21

Q8N0X2
MGRGSGTFERLLDKA

HGS

1

O14964
LERFHGASRVMGTND

WNT6

251

Q9Y6F9
FNDMRALSGGERSFS

SMC6

981

Q96SB8
EFASETGMAGRERLA

SPTBN4

1771

Q9H254
REGALRFMVADDAAA

SH2B2

196

O14492
ARGADRMSSFGDFVA

ATIC

306

P31939
GFSEMGRSRFEEGRL

nan

71

Q6ZWC4
MAAAGGAEGRRAALE

ZNF598

1

Q86UK7
FMLLEAERRRGGGAA

TPRN

61

Q4KMQ1
FGGMVSREFADAREN

WNT3A

161

P56704
QLTSAGRRVVFMGDD

PIGO

166

Q8TEQ8
MAATAREDGASGQER

RCHY1

1

Q96PM5
AATSGRMVEAFARRA

XPNPEP2

496

O43895
MGFSRGDALEALRAS

UBAC2

316

Q8NBM4
SGLRGAMAFALAIRD

SLC9A7

486

Q96T83
RDGFDMFAQTRGNSL

TOM1L2

381

Q6ZVM7
VFRSGEGMGIRLDNA

PC

396

P11498
SLRERVAGSAGMAAL

TFR2

161

Q9UP52
DGSALGRFERMLAAQ

TYMP

336

P19971
MEAAATPAAAGAARR

SLC36A4

1

Q6YBV0
AARAALGMEAADAVT

SIGLEC16

466

A6NMB1
SDLKAASGGRDRRMG

ZNF324B

211

Q6AW86
MRLGLAAAAAAAAAE

ZIC5

281

Q96T25
ADRSAAEMSGRGSVL

FAM90A18

166

P0DV75
AGRLRAERAEKAAGM

MYO9B

701

Q13459