Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbeta-adrenergic receptor kinase activity

GRK2 GRK3

3.11e-054462GO:0047696
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC9A7 SLC36A3 SLC28A3 SLC13A4 CLCN6 SLC30A6

5.74e-05296466GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC9A7 SLC36A3 SLC28A3 SLC13A4 CLCN6 CYB561D2 SLC30A6

1.02e-04477467GO:0022804
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK2 GRK3

1.08e-047462GO:0004703
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC9A7 SLC36A3 SLC28A3 SLC13A4 SLC30A6

6.22e-04301465GO:0022853
GeneOntologyMolecularFunctionopsonin binding

CLEC7A CR1

1.51e-0325462GO:0001846
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A7 SLC30A6

1.76e-0327462GO:0051139
DomainGPCR_kinase

GRK2 GRK3

1.24e-047462IPR000239
DomainMAM_1

ALK MAMDC2

6.97e-0416462PS00740
DomainMAM

ALK MAMDC2

8.85e-0418462PF00629
DomainMAM_dom

ALK MAMDC2

8.85e-0418462IPR000998
DomainMAM_2

ALK MAMDC2

8.85e-0418462PS50060
DomainRGS

GRK2 GRK3

3.35e-0335462PF00615
DomainRGS

GRK2 GRK3

3.35e-0335462SM00315
DomainRGS

GRK2 GRK3

3.54e-0336462PS50132
DomainRGS

GRK2 GRK3

4.15e-0339462IPR016137
DomainPH

OBSCN ARHGEF28 GRK2 GRK3

4.80e-03278464SM00233
DomainPH_DOMAIN

OBSCN ARHGEF28 GRK2 GRK3

4.86e-03279464PS50003
DomainPH_domain

OBSCN ARHGEF28 GRK2 GRK3

4.92e-03280464IPR001849
DomainAGC-kinase_C

GRK2 GRK3

8.40e-0356462IPR000961
DomainAGC_KINASE_CTER

GRK2 GRK3

8.40e-0356462PS51285
DomainS_TK_X

GRK2 GRK3

8.40e-0356462SM00133
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_EXTRINSIC_APOPTOTIC_PATHWAY

CASP3 IFT57

4.97e-055322M48989
Pubmed

Cloning of GRK2 cDNA from S49 murine lymphoma cells.

GRK2 GRK3

1.79e-0624728638670
Pubmed

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.

GRK2 GRK3

1.79e-06247233060647
Pubmed

G protein--coupled receptor kinases.

GRK2 GRK3

1.79e-0624728035170
Pubmed

Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.

GRK2 GRK3

1.79e-06247210198406
Pubmed

G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.

GRK2 GRK3

1.79e-06247211762794
Pubmed

Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.

GRK2 GRK3

5.36e-06347210754297
Pubmed

Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.

GRK2 GRK3

5.36e-06347210085131
Pubmed

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.

GRK2 GRK3

5.36e-0634727761854
Pubmed

The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors.

GRK2 GRK3

5.36e-06347231604529
Pubmed

Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.

GRK2 GRK3

5.36e-06347212130708
Pubmed

Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.

GRK2 GRK3

1.07e-05447221784156
Pubmed

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.

GRK2 GRK3

1.07e-0544728917529
Pubmed

Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C.

GRK2 GRK3

1.07e-0544728662816
Pubmed

Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus.

GRK2 GRK3

1.07e-05447223734232
Pubmed

Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma.

CASP3 ALK

1.07e-05447212036886
Pubmed

Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine.

GRK2 GRK3

1.78e-05547210338466
Pubmed

Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis.

TENM4 ALK

1.78e-05547223991058
Pubmed

Generation of conditional ALK F1174L mutant mouse models for the study of neuroblastoma pathogenesis.

CASP3 ALK

1.78e-05547231218818
Pubmed

Developmental and tumoral vascularization is regulated by G protein-coupled receptor kinase 2.

CASP3 GRK2

1.78e-05547224135140
Pubmed

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

GRK2 GRK3

2.67e-0564729826657
Pubmed

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2.

GRK2 GRK3

2.67e-05647220074556
Pubmed

Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.

GRK2 GRK3

2.67e-05647236451830
Pubmed

Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.

GRK2 GRK3

3.74e-0574728672451
Pubmed

Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.

GRK2 GRK3

3.74e-05747211517230
Pubmed

Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells.

GRK2 GRK3

6.40e-05947234873237
Pubmed

Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein.

CASP3 GRK2

6.40e-05947223729591
Pubmed

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.

GRK2 GRK3

7.99e-05104721869533
Pubmed

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing.

CASP3 CLEC7A

1.86e-041547230606613
Pubmed

Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice.

CASP3 ZFHX4

3.01e-041947234732852
Pubmed

Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease.

CASP3 CLEC7A

5.26e-042547226100917
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

OBSCN PCNX2 SLC9A7 CPAMD8 GALNT10 GRK3 SMG7 SH3RF3

7.85e-04148947828611215
Pubmed

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

CPAMD8 C1GALT1

1.28e-033947219010793
Pubmed

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

CASP3 KIF21B

1.35e-034047229078390
GeneFamilySolute carriers

SLC9A7 SLC36A3 SLC28A3 SLC13A4 SLC30A6

6.96e-04395335752
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A7 SLC28A3 GRK3 IFT57

2.26e-05157474d8e283414a770f05d71f0455d0822e9a9660b115
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A7 SLC28A3 GRK3 IFT57

2.26e-05157474165e98bf944572cafbc06ef43c9eab7bd6bea1c2
ToppCellControl-Myeloid-Monocytes,_Macrophages-Mast-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CASP3 ARL5B IFT57 CYB561D2

2.38e-0515947481782e9e370558d61af5e0c760ac9759d69fb725
ToppCellfacs-Lung-EPCAM-18m-Hematologic-Proliferating_Immune|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 CLEC7A GDPD2 GRK3

2.44e-051604747217730ae14840b935b3bf9aa49becbcbcd8a682
ToppCellfacs-Lung-EPCAM-18m-Hematologic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 CLEC7A GDPD2 GRK3

2.44e-05160474317ef81460c1a31b51119a6309b11be6a8d4ea3e
ToppCellfacs-Lung-EPCAM-18m-Hematologic-leukocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 CLEC7A GDPD2 GRK3

2.44e-05160474e6191240c93da34fc4431a35ef496edf323cb41e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

LHFPL6 CPAMD8 DNAH5 IFT57

2.62e-05163474e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

LHFPL6 CPAMD8 DNAH5 IFT57

3.54e-051764743fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LHFPL6 TENM4 ZFHX4 MAMDC2

3.78e-0517947402c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN TENM4 ZFHX4 DNAH5

4.21e-05184474ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN TENM4 ZFHX4 DNAH5

4.21e-051844742cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN TENM4 ZFHX4 DNAH5

4.21e-051844742b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

LHFPL6 CPAMD8 DNAH5 IFT57

4.30e-05185474673f0c688ae6984bc8027df2da335787924f4137
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LHFPL6 TENM4 ZFHX4 MAMDC2

4.30e-051854746712512100ccef456d2e2bd201d0987986c92ac9
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

SLC9A7 GRK3 CR1 IFT57

4.48e-05187474af1327559f7e01bec070881cae52834917c3da65
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CLEC7A TENM4 ARHGEF28 ALK

4.58e-05188474d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

LHFPL6 TENM4 MAMDC2 TLL2

4.58e-05188474fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

GDPD2 LHFPL6 TENM4 ZFHX4

4.67e-0518947446c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

CLEC7A GRK3 CR1 MAMDC2

4.67e-051894742586f4088721c5debec86c2b211b739fd33713eb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CLEC7A LIPN GRK3 CR1

4.87e-0519147447a2afc4102199b4bc76bd01b2967c8016186462
ToppCell356C-Lymphocytic-B_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC9A7 GRK3 IFT57 IGHE

4.97e-05192474f1ac7fa8159f573d140f0e4cbd15256dcb142980
ToppCell356C-Lymphocytic-B_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC9A7 GRK3 IFT57 IGHE

4.97e-051924741d7a5d15c76ae45551ce104327a2241fbf7d1827
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC7A LIPN GRK2 GRK3

5.07e-05193474cb0fb21510124883e716780bea46575620c366b8
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC7A LIPN GRK2 GRK3

5.07e-051934740c207879f994c227dcd1322faa69ec9e3749cdaa
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC7A LIPN GRK2 GRK3

5.07e-051934740fbbfcc803edc3cd96b35467ad5cc573af07fd67
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC7A LIPN GRK2 GRK3

5.17e-0519447416c6fcbd36d473b883fb5361caca86eb134767ab
ToppCellmedial-2-Hematologic-Nonclassical_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLEC7A LIPN GRK2 GRK3

5.17e-05194474202e5070728191c46161fa7d931f00be1c7559d4
ToppCellmedial-Hematologic-Nonclassical_Monocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLEC7A LIPN GRK2 GRK3

5.17e-05194474002cd317732fc6b0d9a72fb46199f71db5a638a7
ToppCellmedial-Hematologic-Nonclassical_Monocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLEC7A LIPN GRK2 GRK3

5.17e-05194474ac203d388a3a3884e316dec0dcbd408e43c6ef6c
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

PCNX2 LHFPL6 GALNT10 MAMDC2

5.27e-05195474a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellmedial-2-Hematologic-Intermediate_Monocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLEC7A SLC28A3 LIPN GRK2

5.60e-05198474432a26ace5b486695c9a933c0d44b73305b01ded
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LHFPL6 TENM4 ZFHX4 MAMDC2

5.60e-051984749541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCellmedial-Hematologic-Intermediate_Monocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLEC7A SLC28A3 LIPN GRK2

5.60e-05198474dbd7869483c5a67944cb94ced0ee2c7b999adc2e
ToppCellmedial-Hematologic-Intermediate_Monocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CLEC7A SLC28A3 LIPN GRK2

5.60e-051984748f64bb5cd8c3e2d5ef651821b0d59f67d1ca1a12
ToppCellSigmoid-(4)_Monocyte-(40)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

CLEC7A LIPN TENM4 CR1

5.82e-05200474576c0a1098e6a934448705de3673ef798fcf1b26
ToppCellSigmoid-(4)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

CLEC7A LIPN TENM4 CR1

5.82e-052004747f3920a0434d5199c6c8f0b3064a305bb0d87b60
ToppCellSigmoid-Monocyte-Monocyte|Sigmoid / Region, Cell class and subclass

CLEC7A LIPN TENM4 CR1

5.82e-05200474010ca36970cb8894bdbca08779c0ecf56be22fc9
ToppCellSigmoid-Monocyte|Sigmoid / Region, Cell class and subclass

CLEC7A LIPN TENM4 CR1

5.82e-05200474c41bd6ec0f2262fce5cadb37a400d487e6662f49
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC28A3 SLC13A4 TLL2

2.89e-041224737dabf8b4c34a3714f45c3a99c1aa159e2d0b7e9c
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC28A3 SLC13A4 TLL2

2.89e-04122473489a01c71882be5a6d71a19d06574698988c20f6
ToppCellNS-control-d_0-4-Epithelial-Ciliated-diff|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GDPD2 DNAH5 IFT57

4.51e-041424731e57c75e9f28aae2ca99543448433fa7326398ad
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-9|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC9A7 IFT57 IGHE

5.39e-041514732314c004434aed9b7fa1ad01c61c43e5ed4a18ce
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCNX2 CLEC7A GRK3

5.60e-04153473596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCNX2 CLEC7A GRK3

5.60e-041534738cc2667213bfac37545bb63181e88ef1f1834413
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C-8|TCGA-Thymus / Sample_Type by Project: Shred V9

SLC9A7 SLC28A3 IGHE

5.82e-0415547300eef9f93a753a1fe1ab5fd8dae026e7be556cde
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLEC7A SLC9A7 GRK2

5.82e-041554739f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK3 ALK

5.93e-041564735b56217336771baf57d791efcb4e206c6aea83b1
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCNX2 SLC28A3 ZFHX4

5.93e-04156473b28bbdb515317368f1231b0b15d7442352f3b400
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC9A7 CLCN6 TLL2

6.15e-0415847341cf950983f47a9e55d56041b301006b42853b37
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLEC7A LIPN CR1

6.38e-041604732586035a1380bc56814a6db0ca773ad835666042
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLEC7A LIPN CR1

6.38e-041604733b5a335786165391fe983ff0585cd508733793aa
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 C12orf56 ZKSCAN5

6.38e-04160473f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellcontrol-Epithelial-Ciliated-diff|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GDPD2 DNAH5 IFT57

6.50e-04161473ef4b946914a4e2727ed57362dc6965c299520f35
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LHFPL6 TENM4 MAMDC2

6.73e-04163473431221a41d396b09170476179590eaf8a55266d8
ToppCellfacs-Marrow-T_cells-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A XIRP1 GRK3

6.73e-0416347330cd95d4f37bd54c1fde54960cb005db58bdd30c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LHFPL6 TENM4 MAMDC2

6.73e-041634731e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellfacs-Marrow-T_cells-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A XIRP1 GRK3

6.73e-04163473ab934cb986495adfc8dbe5a276577f2a8fb6ee03
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21B SLC9A7 GRK2

6.98e-041654738a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellInfluenza_Severe-cDC|Influenza_Severe / Disease group and Cell class

SLC9A7 SEC61A2 LHFPL6

7.10e-04166473b40bdf0f7f381e25be61188e9f6c294d25a8b824
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

OBSCN PCNX2 SMG7

7.10e-0416647332d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GDPD2 GRK3

7.10e-0416647391eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

PCNX2 ARL5B DCUN1D4

7.10e-04166473a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

LHFPL6 TENM4 SH3RF3

7.35e-04168473968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRK3 SMG7 CLCN6

7.35e-0416847327cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK2 GRK3

7.48e-041694732d3618f78484bd3508b7bdae3a0d0183cdae5057
ToppCellcontrol-Epithelial-Ciliated-diff|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

GDPD2 DNAH5 IFT57

7.61e-04170473334c4103eb6e021766f5638a4ab14b59ad085ac7
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK2 GRK3

7.61e-04170473f08aa6168ff0c20b2083dbf588dd3294e3d9580e
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

OBSCN CLEC7A GRK3

7.61e-041704734232fe937909f93d3736988c707b8f95ce993398
ToppCellfacs-Lung-EPCAM-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 CTRB1 DNAH5

7.61e-0417047382ccba6ec53f6ca0d19949a1277434c565af2983
ToppCellfacs-SCAT-Fat-24m-Myeloid-myeloid_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK2 GRK3

7.61e-0417047313480e5f2de50425e42be0144b876e9aa4006a68
ToppCellfacs-SCAT-Fat-24m-Myeloid-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK2 GRK3

7.61e-04170473d22cd09a43a14045bb1181189fe8accf78fdde3b
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 CTRB1 DNAH5

7.61e-04170473ab19ea729ed8c8361c870e79893d1a95a1e487fa
ToppCellfacs-SCAT-Fat-24m-Myeloid|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK2 GRK3

7.61e-04170473f9968d3735328a39157764343dd40f1ad8bf710d
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

OBSCN LHFPL6 SH3RF3

7.74e-04171473bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK3 MAMDC2

7.74e-0417147325493a4a7b636920e2cfd984542cc500709c9dcf
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK3 MAMDC2

7.74e-04171473508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC9A7 GRK3 CR1

7.74e-041714738e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

PCNX2 CPAMD8 ZFHX4

7.87e-04172473c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLEC7A SLC9A7 GRK3

8.00e-0417347373f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC7A GRK3 MAMDC2

8.00e-0417347363f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A7 GDPD2 GRK3

8.13e-04174473f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

LHFPL6 ALK MAMDC2

8.13e-041744734c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OBSCN ALK MAMDC2

8.13e-04174473f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLEC7A KIF21B LIPN

8.13e-04174473b6e3fa995def40a8fbdfc249fe108c303931a171
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDPD2 GRK3 MAMDC2

8.27e-04175473cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellClub-club-15|World / Class top

SLC9A7 SEC61A2 C12orf56

8.27e-04175473ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

OBSCN CASP3 CLCN6

8.27e-0417547369ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

XIRP1 ZFHX4 MAMDC2

8.41e-041764734ed73c73972334f6dc4229920205547823252fa0
ToppCellEntopeduncular-Endothelial-MURAL|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LHFPL6 XIRP1 MAMDC2

8.41e-04176473b8e52bec78876562a25f0b0de502aa9372b28bd2
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LHFPL6 XIRP1 MAMDC2

8.41e-0417647310c1f31c27e54b70f58f0b0086ac74dee2ce4197
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC36A3 XIRP1 MAMDC2

8.55e-041774731b153fbfe1323dc589de4af73a52149ea5ce6763
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC9A7 LHFPL6 TENM4

8.55e-04177473cbedac0bddb8fc330a464815c905928c553b0fc0
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LHFPL6 XIRP1 MAMDC2

8.55e-041774734553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LHFPL6 SLC28A3 ZFHX4

8.55e-04177473b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

LHFPL6 ALK MAMDC2

8.55e-04177473470f54fe2b21c7350ea471e02039461a3808f700
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC36A3 XIRP1 MAMDC2

8.55e-0417747332fecefba1a55e1f418c9a055236fa11175c692d
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLEC7A SLC9A7 TENM4

8.55e-04177473345cebc19f93970a9a46be139208b300081f5493
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9A7 GDPD2 CTRB1

8.69e-04178473fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC9A7 LHFPL6 TENM4

8.69e-0417847304bfecf5ea5d85c843e48d08718b5d69e7bf834e
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC28A3 TENM4 ARHGEF28

8.83e-04179473fd2cbee532e7b44113410dca82aec7db1a7fb69f
DiseaseRetinal Detachment

CASP3 CPAMD8

1.30e-0411462C0035305
Diseasepreeclampsia

LHFPL6 TENM4 CLCN6

2.49e-0478463EFO_0000668
DiseaseAcute Confusional Senile Dementia

CASP3 CR1 SLC30A6

5.01e-0499463C0546126
DiseasePresenile dementia

CASP3 CR1 SLC30A6

5.01e-0499463C0011265
DiseaseAlzheimer's Disease, Focal Onset

CASP3 CR1 SLC30A6

5.01e-0499463C0750900
DiseaseAlzheimer Disease, Early Onset

CASP3 CR1 SLC30A6

5.01e-0499463C0750901
DiseaseAlzheimer Disease, Late Onset

CASP3 CR1 SLC30A6

5.01e-0499463C0494463
DiseaseFamilial Alzheimer Disease (FAD)

CASP3 CR1 SLC30A6

5.16e-04100463C0276496
DiseaseAlzheimer's Disease

CASP3 CR1 SLC30A6

5.31e-04101463C0002395
DiseaseParkinson's disease (biomarker_via_orthology)

GRK2 GRK3

1.01e-0330462DOID:14330 (biomarker_via_orthology)
Diseaseandrosterone sulfate measurement

ZKSCAN5 ALK

1.22e-0333462EFO_0021117
Diseasepancreatitis (biomarker_via_orthology)

CASP3 CTRB1

1.70e-0339462DOID:4989 (biomarker_via_orthology)
Diseasecolorectal health

PCNX2 LHFPL6 XIRP1

3.81e-03201463EFO_0008460
Diseasemigraine disorder, type 2 diabetes mellitus

SLC28A3 C1GALT1

3.97e-0360462MONDO_0005148, MONDO_0005277
DiseaseUlcerative Colitis

CASP3 KIF21B

4.37e-0363462C0009324
Diseasehypertension (biomarker_via_orthology)

CASP3 GRK2 GRK3

5.35e-03227463DOID:10763 (biomarker_via_orthology)
DiseaseManic Disorder

TENM4 GRK3

5.52e-0371462C0024713

Protein segments in the cluster

PeptideGeneStartEntry
GNHFWKCLFMSGLSE

TDG

156

Q13569
FTLQEWLKGMTSLQC

DCUN1D4

156

Q92564
SADWFSLGCMLFKLL

GRK3

371

P35626
MGLIFAKLWSLFCNQ

ARL5B

1

Q96KC2
DGSWFIQSLCAMLKQ

CASP3

211

P42574
SADWFSLGCMLFKLL

GRK2

371

P25098
FMSLCKSFWDCGLVA

MAMDC2

471

Q7Z304
MRWGLAKLSQFFLCL

ARHGEF28

171

Q8N1W1
CSEFMSLWAGSNKKN

LIPN

256

Q5VXI9
LRSSLNCKSFKWFMT

GALNT10

426

Q86SR1
LSNSRQLKWLSCGFM

FBXO33

246

Q7Z6M2
GFLTLSQGFCKDMWV

PCNX2

856

A6NKB5
SQGFCKDMWVLLFCL

PCNX2

861

A6NKB5
LFTGSKDRSCKMWNL

KIF21B

1321

O75037
MQTSKCDCIWFGLLF

GDPD2

31

Q9HCC8
MNAFLLSALCLLGAW

GUCA2A

1

Q02747
MLLCTWLACFSGKKQ

LHFPL6

181

Q9Y693
SAAQCLSHPWFLKSM

OBSCN

6711

Q5VST9
LTWKVLFCSMSATFT

CLCN6

276

P51797
MFCTLAAWLINKAGR

IFT57

86

Q9NWB7
FGKMFSISCLENLVW

CR1

1431

P17927
SGSMWLTAFVLKSFA

CPAMD8

1206

Q8IZJ3
LLTVSGAWAKQMFTC

IGHE

71

P01854
MASKSWLNFLTFLCG

C1GALT1

1

Q9NS00
WMTQFSLLNKTCLEG

CST9L

131

Q9H4G1
MHWLFLGCNFKETCS

SLC13A4

331

Q9UKG4
SASLLLGMCSLWFTA

CYB561D2

171

O14569
MASLWLLSCFSLVGA

CTRB1

1

P17538
LCSWTKAMASFFSIN

DNAH5

3406

Q8TE73
SLGISRFCLQWASML

TAS2R16

51

Q9NYV7
IFMLGSCAFFSKTWI

SEC61A2

366

Q9H9S3
LCWTQLLALFMSFLG

SMG7

326

Q92540
AFLALLSFMNSALSW

SLC28A3

456

Q9HAS3
LMANWKTFLLFFGTA

SLC36A3

246

Q495N2
PGSKMALQSSFTCWN

ALK

431

Q9UM73
CYLFSMSLNSWDGSK

CLEC7A

131

Q9BXN2
TKFAISWIMSFLQSC

C12orf56

511

Q8IXR9
TLSFWLAGQCMSLKA

C11orf40

141

Q8WZ69
CFSMKSWPNILFQAS

ZFHX4

3471

Q86UP3
MLLGASWLCASKAAA

SH3RF3

1

Q8TEJ3
LNFTSMDLFKSRLCW

TLL2

391

Q9Y6L7
CFMTDVNSWLLTFGF

TENM4

2466

Q6N022
NLICTGFLLMWCSST

SLC30A6

41

Q6NXT4
GFLLMWCSSTNSIAL

SLC30A6

46

Q6NXT4
YGRALKLMSTSNTWC

TTC37

766

Q6PGP7
LMSWSTFLLAEACGF

SLC9A7

366

Q96T83
QLCKMLFLATFFPTW

TMEM147

46

Q9BVK8
HKFTWLFENCPMGSL

XIRP1

726

Q702N8
CGMNFSWSCSLFKHL

ZKSCAN5

806

Q9Y2L8
CSDKMSLLLVYGSWF

WDR43

341

Q15061