Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF597 TBX15 ZEB1 ZBTB7C FEZF2 NPAS3 ZNF343 MECOM POU3F1 ZNF880 ZBTB26 ZNF57 FOXA2 ZBTB7B TBX18 ZBTB7A SALL2 ZBTB32 ZNF550 FEZF1 NFIL3 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 TBX20 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513 TBX6	1.09e-15	1412	97	34	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF597 TBX15 ZEB1 ZBTB7C FEZF2 NPAS3 ZNF343 MECOM POU3F1 ZNF880 ZBTB26 ZNF57 FOXA2 ZBTB7B TBX18 ZBTB7A SALL2 ZBTB32 ZNF550 FEZF1 NFIL3 ZKSCAN3 ZNF264 ZNF799 ZNF664 TBX20 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513 TBX6	1.31e-13	1459	97	32	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF597 TBX15 ZEB1 ZBTB7C FEZF2 MECOM POU3F1 ZNF880 ZBTB26 FOXA2 ZBTB7B TBX18 ZBTB7A SALL2 ZBTB32 FEZF1 NFIL3 ZKSCAN3 ZNF264 ZNF664 TBX20 PRDM15 ZNF426 ZNF513 TBX6	7.56e-10	1244	97	25	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF597 TBX15 ZEB1 ZBTB7C FEZF2 MECOM POU3F1 ZNF880 ZBTB26 FOXA2 ZBTB7B TBX18 ZBTB7A SALL2 ZBTB32 FEZF1 NFIL3 ZKSCAN3 ZNF264 ZNF664 TBX20 PRDM15 ZNF426 ZNF513 TBX6	1.18e-09	1271	97	25	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	TBX15 ZEB1 FEZF2 POU3F1 ZBTB26 ZBTB7B TBX18 ZBTB7A ZBTB32 FEZF1 NFIL3 ZKSCAN3 ZBTB21	6.28e-09	326	97	13	GO:0001217
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	TBX15 ZEB1 FEZF2 POU3F1 ZBTB26 TBX18 ZBTB7A ZBTB32 FEZF1 NFIL3 ZKSCAN3 ZBTB21	4.93e-08	320	97	12	GO:0001227
GeneOntologyMolecularFunction	protein kinase activity	TRPM6 MAK TAOK2 BMX STRADA CLK3 TBCK RPS6KA6 MAPK6 MERTK MAP3K2	1.58e-04	600	97	11	GO:0004672
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TRPM6 MAK TAOK2 BMX STRADA CLK3 TBCK RPS6KA6 MAPK6 MERTK MAP3K2	6.50e-04	709	97	11	GO:0016773
GeneOntologyMolecularFunction	kinase activity	TRPM6 MAK TAOK2 BMX STRADA CLK3 TBCK RPS6KA6 MAPK6 MERTK MAP3K2	1.19e-03	764	97	11	GO:0016301
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	TRPM6 MAK TAOK2 STRADA CLK3 RPS6KA6 MAPK6 MAP3K2	1.48e-03	446	97	8	GO:0004674
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF597 FEZF2 MECOM FOXA2 ZBTB7B SALL2 PLAGL2 TBX20 PRDM15	1.61e-03	560	97	9	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF597 FEZF2 MECOM FOXA2 ZBTB7B SALL2 PLAGL2 TBX20 PRDM15	1.73e-03	566	97	9	GO:0001216
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TRPM6 MAK TAOK2 BMX STRADA CLK3 TBCK SELENOO RPS6KA6 MAPK6 MERTK MAP3K2	1.94e-03	938	97	12	GO:0016772
GeneOntologyMolecularFunction	protein serine kinase activity	TRPM6 MAK TAOK2 CLK3 RPS6KA6 MAPK6 MAP3K2	1.96e-03	363	97	7	GO:0106310
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	TBX15 ZEB1 FEZF2 SHC1 MECOM POU3F1 ZBTB26 RUNX1T1 CBFA2T3 ZBTB7B TBX18 ZBTB7A SALL2 ZBTB32 FEZF1 NFIL3 ZKSCAN3 ZBTB21 TBX20 TBX6	6.57e-06	1399	97	20	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	TBX15 ZEB1 FEZF2 POU3F1 ZBTB26 CBFA2T3 ZBTB7B TBX18 ZBTB7A SALL2 ZBTB32 FEZF1 NFIL3 ZKSCAN3 ZBTB21 TBX20 TBX6	7.57e-06	1053	97	17	GO:0000122
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	TBX15 ZEB1 FEZF2 SHC1 MECOM POU3F1 ZBTB26 RUNX1T1 CBFA2T3 ZBTB7B TBX18 ZBTB7A SALL2 ZBTB32 FEZF1 NFIL3 ZKSCAN3 ZBTB21 TBX20 TBX6	7.61e-06	1413	97	20	GO:1902679
GeneOntologyBiologicalProcess	cell fate specification	TBX15 APC FOXA2 TBX18 TBX20 TBX6	2.52e-05	123	97	6	GO:0001708
GeneOntologyBiologicalProcess	forebrain anterior/posterior pattern specification	FEZF2 FEZF1	1.31e-04	4	97	2	GO:0021797
GeneOntologyBiologicalProcess	anterior/posterior pattern specification	FEZF2 APC FOXA2 TBX18 FEZF1 PLD6 TBX6	1.67e-04	247	97	7	GO:0009952
GeneOntologyBiologicalProcess	pattern specification process	ZEB1 FEZF2 DYNC2H1 APC FOXA2 TBX18 FEZF1 PLD6 TBX20 TBX6	1.84e-04	526	97	10	GO:0007389
GeneOntologyBiologicalProcess	axis specification	APC FOXA2 TBX18 PLD6 TBX6	1.95e-04	113	97	5	GO:0009798
GeneOntologyBiologicalProcess	cell fate commitment	TBX15 FEZF2 APC FOXA2 TBX18 TBX20 PRDM15 TBX6	1.95e-04	338	97	8	GO:0045165
GeneOntologyBiologicalProcess	regulation of acinar cell proliferation	FA2H APC	2.17e-04	5	97	2	GO:1904697
GeneOntologyBiologicalProcess	acinar cell proliferation	FA2H APC	2.17e-04	5	97	2	GO:1990863
MousePheno	small intervertebral disk	ZEB1 TBX18	3.07e-05	2	78	2	MP:0004682
MousePheno	abnormal vertebral articular process morphology	MECOM TBX6	3.07e-05	2	78	2	MP:0004602
MousePheno	abnormal intervertebral disk morphology	ZEB1 MECOM TBX18 KIAA1217 TBX6	3.50e-05	67	78	5	MP:0004173
MousePheno	abnormal symphysis morphology	ZEB1 MECOM TBX18 KIAA1217 TBX6	4.64e-05	71	78	5	MP:0030877
MousePheno	abnormal cartilaginous joint morphology	ZEB1 MECOM TBX18 KIAA1217 TBX6	1.10e-04	85	78	5	MP:0030875
Domain	-	ZNF597 ZEB1 ZBTB7C FEZF2 ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A ZNF800 SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	3.11e-19	679	96	29	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF597 ZEB1 ZBTB7C FEZF2 ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A ZNF800 SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	5.63e-19	694	96	29	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF597 ZEB1 ZBTB7C FEZF2 APTX ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A ZNF800 SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	1.02e-18	775	96	30	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF597 ZEB1 ZBTB7C FEZF2 APTX ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A ZNF800 SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	1.10e-18	777	96	30	PS00028
Domain	Znf_C2H2-like	ZNF597 ZEB1 ZBTB7C FEZF2 APTX ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A ZNF800 SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	2.15e-18	796	96	30	IPR015880
Domain	Znf_C2H2	ZNF597 ZEB1 ZBTB7C FEZF2 APTX ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A ZNF800 SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	2.93e-18	805	96	30	IPR007087
Domain	ZnF_C2H2	ZNF597 ZEB1 ZBTB7C FEZF2 APTX ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A ZNF800 SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	3.25e-18	808	96	30	SM00355
Domain	zf-C2H2	ZNF597 ZBTB7C FEZF2 ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	6.85e-17	693	96	27	PF00096
Domain	BTB	ANKFY1 KLHL28 ZBTB7C ZBTB26 ZBTB7B KLHL29 ZBTB7A ZBTB32 ZBTB21	2.41e-08	131	96	9	PF00651
Domain	KRAB	ZNF597 ZIM2 ZNF343 ZNF880 ZNF57 ZNF285 ZNF550 ZKSCAN3 ZNF264 ZNF799 ZNF439 ZNF443 ZNF426	3.65e-08	358	96	13	PS50805
Domain	KRAB	ZNF597 ZIM2 ZNF343 ZNF880 ZNF57 ZNF285 ZNF550 ZKSCAN3 ZNF264 ZNF799 ZNF439 ZNF443 ZNF426	3.65e-08	358	96	13	PF01352
Domain	KRAB	ZNF597 ZIM2 ZNF343 ZNF880 ZNF57 ZNF285 ZNF550 ZKSCAN3 ZNF264 ZNF799 ZNF439 ZNF443 ZNF426	5.21e-08	369	96	13	SM00349
Domain	KRAB	ZNF597 ZIM2 ZNF343 ZNF880 ZNF57 ZNF285 ZNF550 ZKSCAN3 ZNF264 ZNF799 ZNF439 ZNF443 ZNF426	5.37e-08	370	96	13	IPR001909
Domain	BTB	ANKFY1 KLHL28 ZBTB7C ZBTB26 ZBTB7B KLHL29 ZBTB7A ZBTB32 ZBTB21	1.36e-07	160	96	9	PS50097
Domain	BTB	ANKFY1 KLHL28 ZBTB7C ZBTB26 ZBTB7B KLHL29 ZBTB7A ZBTB32 ZBTB21	3.71e-07	180	96	9	SM00225
Domain	BTB/POZ_dom	ANKFY1 KLHL28 ZBTB7C ZBTB26 ZBTB7B KLHL29 ZBTB7A ZBTB32 ZBTB21	4.67e-07	185	96	9	IPR000210
Domain	SKP1/BTB/POZ	ANKFY1 KLHL28 ZBTB7C ZBTB26 ZBTB7B KLHL29 ZBTB7A ZBTB32 ZBTB21	5.59e-07	189	96	9	IPR011333
Domain	zf-C2H2_6	ZNF597 FEZF2 MECOM ZNF880 SALL2 FEZF1 PLAGL2 ZNF799 ZNF439 ZNF443 ZNF426	6.30e-07	314	96	11	PF13912
Domain	TF_T-box	TBX15 TBX18 TBX20 TBX6	1.48e-06	17	96	4	IPR001699
Domain	TBOX	TBX15 TBX18 TBX20 TBX6	1.48e-06	17	96	4	SM00425
Domain	TF_T-box_CS	TBX15 TBX18 TBX20 TBX6	1.48e-06	17	96	4	IPR018186
Domain	-	TBX15 TBX18 TBX20 TBX6	1.48e-06	17	96	4	2.60.40.820
Domain	TBOX_3	TBX15 TBX18 TBX20 TBX6	1.48e-06	17	96	4	PS50252
Domain	T-box	TBX15 TBX18 TBX20 TBX6	1.48e-06	17	96	4	PF00907
Domain	TBOX_1	TBX15 TBX18 TBX20 TBX6	1.48e-06	17	96	4	PS01283
Domain	TBOX_2	TBX15 TBX18 TBX20 TBX6	1.48e-06	17	96	4	PS01264
Domain	NHR2	RUNX1T1 CBFA2T3	7.82e-05	3	96	2	IPR014896
Domain	NHR2	RUNX1T1 CBFA2T3	7.82e-05	3	96	2	PF08788
Domain	CBFA2T1/2/3	RUNX1T1 CBFA2T3	7.82e-05	3	96	2	IPR013289
Domain	Kinase-like_dom	TRPM6 MAK TAOK2 BMX STRADA CLK3 TBCK RPS6KA6 MAPK6 MERTK MAP3K2	1.05e-04	542	96	11	IPR011009
Domain	p53-like_TF_DNA-bd	TBX15 TBX18 TBX20 TBX6	1.58e-04	53	96	4	IPR008967
Domain	Prot_kinase_dom	MAK TAOK2 BMX STRADA CLK3 TBCK RPS6KA6 MAPK6 MERTK MAP3K2	2.08e-04	489	96	10	IPR000719
Domain	PROTEIN_KINASE_DOM	MAK TAOK2 BMX STRADA CLK3 TBCK RPS6KA6 MAPK6 MERTK MAP3K2	2.22e-04	493	96	10	PS50011
Domain	TAFH	RUNX1T1 CBFA2T3	2.59e-04	5	96	2	SM00549
Domain	TAFH	RUNX1T1 CBFA2T3	2.59e-04	5	96	2	PS51119
Domain	TAFH	RUNX1T1 CBFA2T3	2.59e-04	5	96	2	PF07531
Domain	TAFH_NHR1	RUNX1T1 CBFA2T3	2.59e-04	5	96	2	IPR003894
Domain	TF_Brachyury	TBX20 TBX6	3.87e-04	6	96	2	IPR002070
Domain	Protein_kinase_ATP_BS	MAK TAOK2 BMX CLK3 RPS6KA6 MAPK6 MERTK MAP3K2	7.49e-04	379	96	8	IPR017441
Domain	Pkinase	MAK TAOK2 STRADA CLK3 TBCK RPS6KA6 MAPK6 MAP3K2	7.75e-04	381	96	8	PF00069
Domain	Roc	AGAP1 AGAP3	1.97e-03	13	96	2	PF08477
Domain	MIRO-like	AGAP1 AGAP3	1.97e-03	13	96	2	IPR013684
Domain	CYTOCHROME_B5_2	FA2H FADS1	1.97e-03	13	96	2	PS50255
Domain	CYTOCHROME_B5_1	FA2H FADS1	1.97e-03	13	96	2	PS00191
Domain	Dynein_HC_stalk	DNHD1 DYNC2H1	2.29e-03	14	96	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DYNC2H1	2.29e-03	14	96	2	IPR013602
Domain	DHC_N2	DNHD1 DYNC2H1	2.29e-03	14	96	2	PF08393
Domain	MT	DNHD1 DYNC2H1	2.29e-03	14	96	2	PF12777
Domain	Cyt-b5	FA2H FADS1	2.29e-03	14	96	2	PF00173
Domain	Cyt_B5-like_heme/steroid-bd	FA2H FADS1	2.29e-03	14	96	2	IPR001199
Domain	Cyt-b5	FA2H FADS1	2.29e-03	14	96	2	SM01117
Domain	-	FA2H FADS1	2.29e-03	14	96	2	3.10.120.10
Domain	PROTEIN_KINASE_ATP	MAK TAOK2 BMX CLK3 RPS6KA6 MAPK6 MERTK MAP3K2	2.51e-03	459	96	8	PS00107
Domain	DHC_fam	DNHD1 DYNC2H1	2.63e-03	15	96	2	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DYNC2H1	2.63e-03	15	96	2	IPR004273
Domain	Dynein_heavy	DNHD1 DYNC2H1	2.63e-03	15	96	2	PF03028
Domain	Kelch	KLHL28 KLHL29 KLHDC8A	3.31e-03	58	96	3	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KLHL28 KLHL29 KLHDC8A	3.47e-03	59	96	3	IPR011043
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	ZBTB7C ZBTB26 ZBTB7B ZBTB7A ZBTB32 ZBTB21	2.56e-08	63	98	6	34351428
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ZNF597 TBX15 ZNF343 POU3F1 ZBTB26 FOXA2 ZBTB7B TBX18 ZBTB7A ZBTB32 TBX20 TBX6	4.56e-08	544	98	12	28473536
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TBX15 ZEB1 ANKFY1 POU3F1 BRD3 ZBTB7B ZBTB7A NFIL3 ZKSCAN3 ZBTB21 PLAGL2 TBX20 ZNF426 ZNF513	6.42e-08	808	98	14	20412781
Pubmed	Tbx18 and Tbx15 null-like phenotypes in mouse embryos expressing Tbx6 in somitic and lateral plate mesoderm.	TBX15 TBX18 TBX6	8.66e-08	4	98	3	20832395
Pubmed	The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.	ZBTB7C ZBTB7B ZBTB7A	2.16e-07	5	98	3	15729333
Pubmed	A census of human transcription factors: function, expression and evolution.	TBX15 ZEB1 NPAS3 POU3F1 FOXA2 ZBTB7B TBX18 ZBTB7A SALL2 NFIL3 PLAGL2 TBX20 TBX6	1.67e-06	908	98	13	19274049
Pubmed	Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression.	TBX15 TBX18 TBX20 TBX6	2.28e-06	33	98	4	18356246
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FASTKD2 LRCH1 NPLOC4 TAOK2 ZBTB21 ANKIB1 PLAGL2 CEP126 MTREX AGAP1	2.58e-06	529	98	10	14621295
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZEB1 ANKFY1 APC MECOM MSTO1 SALL2 KIF15 ZKSCAN3 ZBTB21	2.94e-06	418	98	9	34709266
Pubmed	Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors.	TBX15 TBX18 TBX6	3.52e-06	11	98	3	17584735
Pubmed	dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila.	FEZF2 FEZF1	7.86e-06	2	98	2	20152183
Pubmed	Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth.	APC BMX	7.86e-06	2	98	2	22593188
Pubmed	The hcKrox gene family regulates multiple extracellular matrix genes.	ZBTB7B ZBTB7A	7.86e-06	2	98	2	11691585
Pubmed	Fez family transcription factors: controlling neurogenesis and cell fate in the developing mammalian nervous system.	FEZF2 FEZF1	7.86e-06	2	98	2	24913420
Pubmed	An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division.	FEZF2 FEZF1	7.86e-06	2	98	2	28245922
Pubmed	Zbtb7a and Zbtb7b: Opening naïve loci to reprogram ESCs.	ZBTB7B ZBTB7A	7.86e-06	2	98	2	33627571
Pubmed	Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex.	FEZF2 FEZF1	7.86e-06	2	98	2	16314561
Pubmed	ETO-2, a new member of the ETO-family of nuclear proteins.	RUNX1T1 CBFA2T3	7.86e-06	2	98	2	10022820
Pubmed	The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.	PECAM1 TBX18 TBX20	1.18e-05	16	98	3	21350012
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PATL1 CPT1A NPLOC4 KLHL29 ZBTB7A DPP9 KIAA1217 TBCK KCNMA1 ANKIB1 MAPK6 PLOD1 PRDM15 AGAP1 AGAP3	1.79e-05	1489	98	15	28611215
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	NPAS3 ZBTB7B TAOK2 ZBTB32 CEP126 AGAP1 DNPEP TBX6	1.89e-05	402	98	8	24722188
Pubmed	A dorsal-ventral gradient of Wnt3a/β-catenin signals controls mouse hindgut extension and colon formation.	APC FOXA2 TBX6	2.03e-05	19	98	3	32156757
Pubmed	miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition.	ZEB1 SHC1	2.35e-05	3	98	2	21527937
Pubmed	CBFA2T1, a gene rearranged in human leukemia, is a member of a multigene family.	RUNX1T1 CBFA2T3	2.35e-05	3	98	2	9790752
Pubmed	PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via β-catenin-dependent regulation of ZEB1.	ZEB1 PLAGL2	2.35e-05	3	98	2	31827238
Pubmed	Myeloid translocation genes differentially regulate colorectal cancer programs.	APC CBFA2T3	2.35e-05	3	98	2	27270437
Pubmed	CNS erythroblastic sarcoma: a potential emerging pediatric tumor type characterized by NFIA::RUNX1T1/3 fusions.	RUNX1T1 CBFA2T3	2.35e-05	3	98	2	38243303
Pubmed	Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.	APC BRD3	2.35e-05	3	98	2	37043564
Pubmed	RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature.	CBFA2T3 ZBTB7A	2.35e-05	3	98	2	26968532
Pubmed	β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.	ZEB1 APC	2.35e-05	3	98	2	22080605
Pubmed	Zinc finger protein 277 is an intestinal transit-amplifying cell marker and colon cancer oncogene.	ZEB1 APC	2.35e-05	3	98	2	35015732
Pubmed	ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.	RUNX1T1 ZBTB7A	2.35e-05	3	98	2	27252013
Pubmed	Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo.	PECAM1 FOXA2 TBX6	2.78e-05	21	98	3	10421635
Pubmed	Murine embryonic stem cell-derived pyramidal neurons integrate into the cerebral cortex and appropriately project axons to subcortical targets.	FEZF2 POU3F1 FEZF1	3.69e-05	23	98	3	20089898
Pubmed	Molecular architecture of the developing mouse brain.	FEZF2 POU3F1 FOXA2 TBX18 FEZF1	3.74e-05	132	98	5	34321664
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	APC CCDC77 THOC2 LRCH1 MTREX PLOD1 MAP3K2 AGAP3	3.95e-05	446	98	8	24255178
Pubmed	Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19.	TBX18 TBX6	4.70e-05	4	98	2	9888994
Pubmed	The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function.	FOXA2 TBX20	4.70e-05	4	98	2	23988578
Pubmed	Presomitic mesoderm-specific expression of the transcriptional repressor Hes7 is controlled by E-box, T-box, and Notch signaling pathways.	TBX18 TBX6	4.70e-05	4	98	2	29895619
Pubmed	Selective role of a distinct tyrosine residue on Tie2 in heart development and early hematopoiesis.	PECAM1 SHC1	4.70e-05	4	98	2	15899871
Pubmed	Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins.	RUNX1T1 CBFA2T3	4.70e-05	4	98	2	14703694
Pubmed	ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription.	RUNX1T1 CBFA2T3	4.70e-05	4	98	2	16966434
Pubmed	Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart.	TBX18 TBX20	4.70e-05	4	98	2	16677630
Pubmed	Estrogen receptor α or β loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFβ and HNF3β signaling.	APC FOXA2	4.70e-05	4	98	2	24104551
Pubmed	A STAT3-dependent transcriptional circuitry inhibits cytotoxic gene expression in T cells.	ZBTB7B ZBTB7A	4.70e-05	4	98	2	29180433
Pubmed	Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.	PECAM1 FOXA2 TBX6	4.77e-05	25	98	3	19786569
Pubmed	APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart.	APC TBX18 TBX20	5.38e-05	26	98	3	26493106
Pubmed	Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2.	PECAM1 TBX18 TBX20	6.75e-05	28	98	3	15901664
Pubmed	Critical role of phosphodiesterase 2A in mouse congenital heart defects.	PECAM1 TBX18 TBX20	6.75e-05	28	98	3	29409032
Pubmed	Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2.	TBX18 TBX6	7.82e-05	5	98	2	18849530
Pubmed	Regional expression of MTG genes in the developing mouse central nervous system.	RUNX1T1 CBFA2T3	7.82e-05	5	98	2	19618476
Pubmed	Transcriptional repression by leukaemia-associated ETO family members can be independent of oligomerization and coexpressed hSIN3B and N-CoR.	RUNX1T1 CBFA2T3	7.82e-05	5	98	2	18586123
Pubmed	Neuropilin-1 expression in cancer and development.	PECAM1 APC	7.82e-05	5	98	2	22025255
Pubmed	The proto-oncoprotein KR-POK represses transcriptional activation of CDKN1A by MIZ-1 through competitive binding.	ZBTB7C ZBTB7A	7.82e-05	5	98	2	21804610
Pubmed	Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium.	PECAM1 BMX	7.82e-05	5	98	2	11416142
Pubmed	Cloning and characterization of mCtBP2, a co-repressor that associates with basic Krüppel-like factor and other mammalian transcriptional regulators.	ZEB1 MECOM	7.82e-05	5	98	2	9724649
Pubmed	The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation.	ZBTB7B ZBTB7A	7.82e-05	5	98	2	23041065
Pubmed	Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription.	RUNX1T1 CBFA2T3	7.82e-05	5	98	2	18039847
Pubmed	A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation.	FOXA2 TBX18 TBX6	8.33e-05	30	98	3	32597756
Pubmed	ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.	PECAM1 FOXA2 TBX6	8.33e-05	30	98	3	18462699
Pubmed	Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.	ZEB1 FEZF2 POU3F1 SALL2	8.76e-05	82	98	4	31073041
Pubmed	Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals.	FOXA2 TBX18 MAPK6	1.01e-04	32	98	3	38110169
Pubmed	MLL4 is required after implantation, whereas MLL3 becomes essential during late gestation.	PECAM1 FOXA2 TBX6	1.11e-04	33	98	3	32439762
Pubmed	Control of Regulatory T Cell Differentiation by the Transcription Factors Thpok and LRF.	ZBTB7B ZBTB7A	1.17e-04	6	98	2	28754678
Pubmed	Independent origins of fetal liver haematopoietic stem and progenitor cells.	PECAM1 MECOM	1.17e-04	6	98	2	36104564
Pubmed	The Sox17-mCherry fusion mouse line allows visualization of endoderm and vascular endothelial development.	PECAM1 FOXA2	1.17e-04	6	98	2	22121118
Pubmed	Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.	RUNX1T1 CBFA2T3	1.17e-04	6	98	2	23251453
Pubmed	Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors.	PECAM1 APC	1.17e-04	6	98	2	12626757
Pubmed	Canonical TGFβ signaling induces collective invasion in colorectal carcinogenesis through a Snail1- and Zeb1-independent partial EMT.	ZEB1 APC	1.17e-04	6	98	2	35075245
Pubmed	High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity.	APC CPT1A	1.17e-04	6	98	2	34107251
Pubmed	A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.	ZBTB7B ZBTB7A	1.17e-04	6	98	2	25129370
Pubmed	Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.	FEZF2 FOXA2 FEZF1	1.45e-04	36	98	3	18094027
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	SHC1 APC CCDC77 NPLOC4 ZBTB7A CLK3 ZBTB21 PRDM15 WDR48	1.46e-04	689	98	9	36543142
Pubmed	Ezh2 restricts the smooth muscle lineage during mouse lung mesothelial development.	TBX15 TBX18	1.64e-04	7	98	2	27578795
Pubmed	Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo.	PECAM1 FOXA2	1.64e-04	7	98	2	28926609
Pubmed	Primate gastrulation and early organogenesis at single-cell resolution.	FOXA2 TBX6	1.64e-04	7	98	2	36517595
Pubmed	An improved method for three-dimensional reconstruction of protein expression patterns in intact mouse and chicken embryos and organs.	PECAM1 FOXA2	1.64e-04	7	98	2	17478445
Pubmed	A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.	ZBTB32 WDR48	1.64e-04	7	98	2	18082604
Pubmed	PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.	PECAM1 ARHGEF12	1.64e-04	7	98	2	23467409
Pubmed	Ts65Dn -- localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome.	ZBTB21 PRDM15	1.64e-04	7	98	2	11528125
Pubmed	The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies.	RUNX1T1 CBFA2T3	1.64e-04	7	98	2	12242670
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF57 ZNF550 ZNF264 ZNF799 MTREX	1.66e-04	181	98	5	37372979
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	TBX15 ANKFY1 NPAS3 POU3F1 BRD3 ZBTB7B SALL2 PLAGL2 ZNF426	1.81e-04	709	98	9	22988430
Pubmed	Transcriptional network orchestrating regional patterning of cortical progenitors.	FEZF2 NPAS3 POU3F1	1.84e-04	39	98	3	34921112
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ZNF597 TBX15 APC RUNX1T1 ZBTB7B TBX18 ZBTB32 PLAGL2 TBX20 ZNF513	1.87e-04	877	98	10	20211142
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ANKFY1 RALGAPA2 KIAA1217 ZBTB21	2.12e-04	103	98	4	10574462
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	TBX15 POU3F1 RUNX1T1 TBX18 NFIL3	2.13e-04	191	98	5	24146773
Pubmed	Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.	FEZF2 PECAM1 FEZF1	2.14e-04	41	98	3	25810521
Pubmed	Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair.	PECAM1 TBX18	2.18e-04	8	98	2	34124060
Pubmed	Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis.	PECAM1 MERTK	2.18e-04	8	98	2	19729839
Pubmed	Intra-aortic clusters undergo endothelial to hematopoietic phenotypic transition during early embryogenesis.	PECAM1 MECOM	2.18e-04	8	98	2	22558218
Pubmed	ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain.	RUNX1T1 CBFA2T3	2.18e-04	8	98	2	11533236
Pubmed	BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis.	FOXA2 TBX6	2.18e-04	8	98	2	17117439
Pubmed	The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo.	PECAM1 SHC1	2.18e-04	8	98	2	10809671
Pubmed	Developmental origin of age-related coronary artery disease.	PECAM1 TBX18	2.18e-04	8	98	2	26054850
Pubmed	Extracardiac control of embryonic cardiomyocyte proliferation and ventricular wall expansion.	PECAM1 TBX18	2.18e-04	8	98	2	25560321
Pubmed	The orphan steroid receptor Nur77 family member Nor-1 is essential for early mouse embryogenesis.	FOXA2 TBX6	2.18e-04	8	98	2	13129926
Pubmed	Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis.	TBX18 TBX6	2.18e-04	8	98	2	19956724
Pubmed	Brachyury and related Tbx proteins interact with the Mixl1 homeodomain protein and negatively regulate Mixl1 transcriptional activity.	TBX20 TBX6	2.18e-04	8	98	2	22164283
Pubmed	A GO catalogue of human DNA-binding transcription factors.	ZIM2 ZNF285 ZNF800	2.30e-04	42	98	3	34673265
Interaction	ZBTB7C interactions	ZBTB7C ZBTB7B KLHL29 ZBTB7A	3.60e-06	22	98	4	int:ZBTB7C
Cytoband	19p13.2	ZNF799 ZNF439 ZNF443 ZNF426	1.51e-03	229	98	4	19p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	ZNF57 ZBTB7A DPP9 ZNF799 ZNF439 ZNF443 ZNF426	1.64e-03	797	98	7	chr19p13
Cytoband	17q23.3	PECAM1 STRADA	1.89e-03	30	98	2	17q23.3
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF597 ZEB1 ZBTB7C FEZF2 ZIM2 ZNF343 MECOM ZNF880 ZBTB26 ZNF57 ZNF285 ZBTB7B ZBTB7A ZNF800 SALL2 ZBTB32 ZNF550 FEZF1 ZKSCAN3 ZBTB21 PLAGL2 ZNF264 ZNF799 ZNF664 ZNF439 PRDM15 ZNF443 ZNF426 ZNF513	2.93e-21	718	77	29	28
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ANKFY1 KLHL28 ZBTB7C ZBTB26 ZBTB7B KLHL29 ZBTB7A ZBTB32 ZBTB21	5.42e-09	134	77	9	861
GeneFamily	T-boxes	TBX15 TBX18 TBX20 TBX6	8.89e-07	18	77	4	766
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP1 AGAP3	2.34e-03	17	77	2	1291
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	MECOM PRDM15	2.34e-03	17	77	2	1197
GeneFamily	Zinc fingers MYND-type	RUNX1T1 CBFA2T3	3.57e-03	21	77	2	87
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	TAOK2 MAP3K2	4.65e-03	24	77	2	654
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS	TBX15 POMT2 SHC1 ZIM2 FASTKD2 ZNF57 KLHL29 KIAA1217 KCNMA1 ZNF264 MAPK6 MTREX ZNF664 AGAP1 MAP3K2	5.02e-06	1009	98	15	M157
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	TRPM6 DYNC2H1 MECOM LRCH1 KIAA1217 NHS AGAP1	1.35e-05	208	98	7	M39233
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 MECOM RALGAPA2 TAOK2 KIAA1217	3.03e-07	200	98	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZEB1 PECAM1 MECOM RUNX1T1 BMX KIAA1217	2.83e-06	179	98	6	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	PDE1C ZEB1 PECAM1 ARHGEF12 RALGAPA2 KIAA1217	3.02e-06	181	98	6	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZEB1 ZBTB7C PECAM1 MECOM RUNX1T1 RALGAPA2	3.22e-06	183	98	6	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRPM6 DYNC2H1 FA2H MECOM RPS6KA6 NHS	3.76e-06	188	98	6	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SLC4A8 FA2H KIAA1217 KCNMA1 NHS AGAP1	3.76e-06	188	98	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PDE1C ZEB1 PECAM1 MECOM RALGAPA2 KIAA1217	4.00e-06	190	98	6	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZEB1 PECAM1 MECOM RUNX1T1 RALGAPA2 BMX	4.12e-06	191	98	6	50601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell	Control-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	ZEB1 PECAM1 ARHGEF12 RUNX1T1 RALGAPA2 KIAA1217	4.12e-06	191	98	6	c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE1C ZEB1 PECAM1 ARHGEF12 RALGAPA2 KIAA1217	4.78e-06	196	98	6	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	nucseq-Endothelial-Endothelial_Vascular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE1C ZEB1 PECAM1 RUNX1T1 RALGAPA2 KIAA1217	4.78e-06	196	98	6	686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	PDE1C ZEB1 PECAM1 ARHGEF12 RALGAPA2 KIAA1217	4.78e-06	196	98	6	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	PDE1C ZEB1 PECAM1 RALGAPA2 LRCH1 KIAA1217	4.92e-06	197	98	6	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	nucseq-Endothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE1C ZEB1 PECAM1 RUNX1T1 RALGAPA2 KIAA1217	4.92e-06	197	98	6	ebf9be068eaa658493fa7884fd19f34642922acb
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 ZEB1 ZBTB7C RUNX1T1 KLHL29 TBX18	5.21e-06	199	98	6	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 ZEB1 ZBTB7C RUNX1T1 KLHL29 TBX18	5.21e-06	199	98	6	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 RALGAPA2 ZNF800 KIAA1217	5.36e-06	200	98	6	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 MECOM TAOK2 KIAA1217	5.36e-06	200	98	6	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 MECOM TAOK2 KIAA1217	5.36e-06	200	98	6	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POMT2 ZBTB7C PECAM1 MECOM BMX	3.22e-05	165	98	5	62457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF597 ZBTB7C NPAS3 RUNX1T1 TAOK2	3.31e-05	166	98	5	9d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PECAM1 CBFA2T3 RALGAPA2 TAOK2 BMX	3.51e-05	168	98	5	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PECAM1 CBFA2T3 RALGAPA2 TAOK2 BMX	3.51e-05	168	98	5	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	3'_v3-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	TRPM6 MAK CBFA2T3 ZNF439 WDR48	3.71e-05	170	98	5	4dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	5.00e-05	181	98	5	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE1C PECAM1 MECOM CBFA2T3 BMX	5.27e-05	183	98	5	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ZEB1 PECAM1 MECOM RALGAPA2 BMX	5.41e-05	184	98	5	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ZEB1 SLC4A8 NPAS3 MECOM NHS	5.55e-05	185	98	5	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	5.55e-05	185	98	5	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PECAM1 MECOM LRCH1 BMX MERTK	5.69e-05	186	98	5	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PECAM1 APC CBFA2T3 TAOK2 BMX	5.69e-05	186	98	5	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPAS3 RUNX1T1 KIAA1217 KLHDC8A NHS	5.84e-05	187	98	5	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRPM6 ZEB1 PECAM1 RUNX1T1 RALGAPA2	5.84e-05	187	98	5	e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ZEB1 PECAM1 MECOM RUNX1T1 RALGAPA2	5.84e-05	187	98	5	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SLC4A8 ZBTB7C LRCH1 NHS AGAP1	5.84e-05	187	98	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 RUNX1T1 KIAA1217	5.84e-05	187	98	5	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|368C / Donor, Lineage, Cell class and subclass (all cells)	FOXA2 DENND11 KIAA1217 PLAGL2 PRDM15	5.84e-05	187	98	5	b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	FOXA2 DENND11 KIAA1217 PLAGL2 PRDM15	5.84e-05	187	98	5	61c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	5.84e-05	187	98	5	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	PECAM1 MECOM RUNX1T1 RALGAPA2 BMX	5.84e-05	187	98	5	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDE1C PECAM1 MECOM CBFA2T3 BMX	5.99e-05	188	98	5	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	ZEB1 PECAM1 MECOM RALGAPA2 BMX	5.99e-05	188	98	5	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZEB1 ZBTB7C RUNX1T1 TBX18 KIAA1217	5.99e-05	188	98	5	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	PDE1C PECAM1 CBFA2T3 KIAA1217 AGAP1	5.99e-05	188	98	5	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	ZEB1 PECAM1 MECOM RUNX1T1 BMX	6.14e-05	189	98	5	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZEB1 PECAM1 MECOM RALGAPA2 BMX	6.14e-05	189	98	5	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	ZEB1 PECAM1 MECOM RALGAPA2 BMX	6.14e-05	189	98	5	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	PDE1C ZEB1 PECAM1 RALGAPA2 KIAA1217	6.30e-05	190	98	5	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZEB1 PECAM1 MECOM RALGAPA2 BMX	6.30e-05	190	98	5	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PECAM1 MECOM RUNX1T1 BMX MERTK	6.30e-05	190	98	5	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	6.30e-05	190	98	5	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZEB1 PECAM1 MECOM RUNX1T1 BMX	6.30e-05	190	98	5	f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	6.45e-05	191	98	5	f229abf69a1217194f74b0502486907e07dba989
ToppCell	Control-Endothelial-VE_Capillary_B\|Control / Disease state, Lineage and Cell class	ZEB1 ARHGEF12 RUNX1T1 RALGAPA2 KIAA1217	6.45e-05	191	98	5	322237793a1278bafb14e63cab688b353e352dcc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZEB1 ZBTB7C PECAM1 NPAS3 RALGAPA2	6.61e-05	192	98	5	1ee4783051ec94ea94600f040edcb385fc4289f1
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	6.61e-05	192	98	5	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	PBMC-Severe-cDC_0\|Severe / Compartment, Disease Groups and Clusters	FADS1 MERTK PLOD1 SOD2 AGAP3	6.61e-05	192	98	5	4f4774b925058191673b4ba4b4d05b8b37f61795
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ZEB1 DYNC2H1 MECOM KLHL29 AGAP1	6.61e-05	192	98	5	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE1C ZEB1 PECAM1 RALGAPA2 KIAA1217	6.78e-05	193	98	5	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	6.78e-05	193	98	5	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	6.78e-05	193	98	5	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 ARHGEF12 RALGAPA2	6.78e-05	193	98	5	ad2df9b77999780860141be6ec366afc0172a331
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PDE1C ZEB1 PECAM1 RALGAPA2 KIAA1217	6.78e-05	193	98	5	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	Control-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	ARHGEF12 MECOM RUNX1T1 RALGAPA2 BMX	6.78e-05	193	98	5	52c0f2c7af57436f23e0c0e0c87086c47695e2c4
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	6.78e-05	193	98	5	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE1C ZEB1 PECAM1 RALGAPA2 KIAA1217	6.78e-05	193	98	5	ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PECAM1 CBFA2T3 RALGAPA2 TAOK2 BMX	6.95e-05	194	98	5	c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 RUNX1T1 KIAA1217	6.95e-05	194	98	5	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	6.95e-05	194	98	5	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 RUNX1T1 KIAA1217	6.95e-05	194	98	5	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZEB1 PECAM1 ARHGEF12 MECOM KIAA1217	6.95e-05	194	98	5	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE1C ZEB1 PECAM1 ARHGEF12 KIAA1217	6.95e-05	194	98	5	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZEB1 ZBTB7C PECAM1 NPAS3 RUNX1T1	6.95e-05	194	98	5	b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCell	Adult-Endothelial\|Adult / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 RUNX1T1 KIAA1217	6.95e-05	194	98	5	963b3fbee0575af8379baa397ace65949eaf34f7
ToppCell	Control-Endothelial\|Control / Disease state, Lineage and Cell class	ZEB1 ARHGEF12 RUNX1T1 RALGAPA2 KIAA1217	6.95e-05	194	98	5	485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DYNC2H1 ARHGEF12 KIAA1217 CEP126 AGAP1	7.12e-05	195	98	5	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PECAM1 CBFA2T3 RALGAPA2 TAOK2 BMX	7.12e-05	195	98	5	df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCell	Control-Endothelial-VE_Arterial\|Control / Disease state, Lineage and Cell class	ARHGEF12 MECOM RUNX1T1 RALGAPA2 BMX	7.12e-05	195	98	5	56c66a3655820961e1390b8f4bcc5618e8d0c5a8
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZEB1 PECAM1 RUNX1T1 RALGAPA2 BMX	7.12e-05	195	98	5	023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DYNC2H1 ARHGEF12 KIAA1217 CEP126 AGAP1	7.12e-05	195	98	5	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	Children_(3_yrs)-Endothelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 RUNX1T1 KIAA1217	7.12e-05	195	98	5	094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZEB1 PECAM1 MECOM RUNX1T1 BMX	7.29e-05	196	98	5	cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell	Endothelial\|World / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 RALGAPA2 KIAA1217	7.29e-05	196	98	5	96c6d78482a130ce4e29f6629972a06d10d7530e
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 PDE1C TBX18 NFIL3 NHS	7.47e-05	197	98	5	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZBTB7C NPAS3 KIAA1217 KCNMA1 NHS	7.47e-05	197	98	5	107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDE1C ZEB1 PECAM1 RALGAPA2 KIAA1217	7.47e-05	197	98	5	6a3c647af41fea923311562575a0d656fbc13cbe
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC4A8 NPAS3 KIAA1217 KCNMA1 NHS	7.65e-05	198	98	5	1fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	PDE1C ZEB1 PECAM1 RALGAPA2 KIAA1217	7.83e-05	199	98	5	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 RALGAPA2 KIAA1217	8.02e-05	200	98	5	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 RALGAPA2 KIAA1217	8.02e-05	200	98	5	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 TAOK2 KIAA1217	8.02e-05	200	98	5	eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1C ZEB1 RUNX1T1 KLHL29 NFIL3	8.02e-05	200	98	5	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 RALGAPA2 KIAA1217	8.02e-05	200	98	5	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 TAOK2 KIAA1217	8.02e-05	200	98	5	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 ARHGEF12 KIAA1217 PLOD1	8.02e-05	200	98	5	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-dn_T\|Int-URO / Disease, condition lineage and cell class	BRD3 LRCH1 TBCK MAPK6 ZNF513	8.02e-05	200	98	5	020439d9e70fff7246650ab0e9105236688c3ec3
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	PECAM1 MECOM RUNX1T1 BMX MERTK	8.02e-05	200	98	5	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ZEB1 PECAM1 SHC1 ARHGEF12 KIAA1217	8.02e-05	200	98	5	f15fffefe372005c33e31845982e2d2714ac26af
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)--\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	DNHD1 KIF15 RPS6KA6 PLD6	8.55e-05	105	98	4	c7528276fee8f6d2cb4639069bc87413b0288025
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Otx2_(ventral_lateral_geniculate_nucleus,_magnocellular_part_(VLGMC)?)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	DNHD1 KIF15 RPS6KA6 PLD6	8.55e-05	105	98	4	7bcf3345a21a1ade717128be127e9fe12ae40011
Drug	Bupropion hydrochloride [31677-93-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A	POMT2 ANKFY1 DYNC2H1 ARHGEF12 CPT1A ZBTB7A MSL3 WDR48	2.29e-06	198	98	8	6256_DN
Disease	Large cell carcinoma of lung	TRPM6 BMX RPS6KA6 MAP3K2	3.53e-06	32	96	4	C0345958
Disease	phosphatidylcholine (16:0/22:5n3, 18:1/20:4) measurement	CPT1A FADS1	1.04e-04	5	96	2	EFO_0800467
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 BRD3 KCNMA1 MERTK SOD2	1.26e-04	148	96	5	C0279702
Disease	osteoarthritis, knee, body mass index	TBX15 TAOK2 MAPK6	3.25e-04	41	96	3	EFO_0004340, EFO_0004616
Disease	diastolic blood pressure, systolic blood pressure	TBX15 ANKFY1 DYNC2H1 MECOM CBFA2T3 LRCH1 TBX18 ZNF800 TBX20	3.40e-04	670	96	9	EFO_0006335, EFO_0006336
Disease	Childhood Medulloblastoma	APC BRD3 STRADA	3.75e-04	43	96	3	C0278510
Disease	Melanotic medulloblastoma	APC BRD3 STRADA	3.75e-04	43	96	3	C1275668
Disease	Medullomyoblastoma	APC BRD3 STRADA	3.75e-04	43	96	3	C0205833
Disease	Desmoplastic Medulloblastoma	APC BRD3 STRADA	3.75e-04	43	96	3	C0751291
Disease	Adult Medulloblastoma	APC BRD3 STRADA	3.75e-04	43	96	3	C0278876
Disease	cortical surface area measurement	TRPM6 NPAS3 APC ARHGEF12 MECOM RUNX1T1 LRCH1 NPLOC4 KLHL29 MAPK6 AGAP1 AGAP3 TBX6	4.14e-04	1345	96	13	EFO_0010736
Disease	trypsin-3 measurement	CBFA2T3 ZNF799	5.65e-04	11	96	2	EFO_0020791
Disease	level of Sterol ester (27:1/20:5) in blood serum	CPT1A FADS1	5.65e-04	11	96	2	OBA_2045197
Disease	Medulloblastoma	APC BRD3 STRADA	5.85e-04	50	96	3	C0025149
Disease	Squamous cell carcinoma of the head and neck	TBCK MERTK SOD2	6.57e-04	52	96	3	C1168401
Disease	arachidonoylcarnitine (C20:4) measurement	CPT1A FADS1	6.77e-04	12	96	2	EFO_0800544
Disease	anemia (implicated_via_orthology)	SLC4A8 APC	1.07e-03	15	96	2	DOID:2355 (implicated_via_orthology)
Disease	Polyposis, Adenomatous Intestinal	APC SOD2	1.22e-03	16	96	2	C2713442
Disease	Familial Intestinal Polyposis	APC SOD2	1.22e-03	16	96	2	C2713443
Disease	Adenomatous Polyposis Coli	APC SOD2	1.38e-03	17	96	2	C0032580
Disease	Nuclear non-senile cataract	GJA3 NHS	1.55e-03	18	96	2	C1112705
Disease	Nuclear cataract	GJA3 NHS	1.55e-03	18	96	2	C0392557
Disease	Pancreatic carcinoma	APC SOD2	1.73e-03	19	96	2	C0235974
Disease	Retinitis pigmentosa	MAK MERTK ZNF513	1.83e-03	74	96	3	cv:C0035334
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	PDE1C NPAS3 RUNX1T1 ZNF800 ZNF799 ZNF443	1.94e-03	398	96	6	EFO_0003756, EFO_0003888, EFO_0004337
Disease	birth weight	TBX15 ZBTB26 ZBTB7B KLHL29 NFIL3 TBX20	1.96e-03	399	96	6	EFO_0004344
Disease	gastric ulcer	MECOM ZNF800	2.11e-03	21	96	2	EFO_0009454
Disease	Splenomegaly	APC MECOM	2.32e-03	22	96	2	C0038002
Disease	Cardiomegaly	SHC1 TBX20 SOD2	2.45e-03	82	96	3	C0018800
Disease	Cardiac Hypertrophy	SHC1 TBX20 SOD2	2.45e-03	82	96	3	C1383860
Disease	neuroimaging measurement	APC ARHGEF12 RUNX1T1 LRCH1 TAOK2 FADS1 ZBTB32 MAPK6 AGAP1 AGAP3	2.52e-03	1069	96	10	EFO_0004346
Disease	BMI-adjusted fasting blood glucose measurement	FOXA2 FADS1	2.53e-03	23	96	2	EFO_0008036
Disease	Dystonia	FA2H APTX FASTKD2	2.81e-03	86	96	3	C0013421

Protein segments in the cluster

Peptide	Gene	Start	Entry
YHPSLHDYMQNIHGK	AGAP3	401	Q96P47
HDYHDIIKHPMDLST	BRD3	346	Q15059
HPSLHDYMQNVHGKE	AGAP1	381	Q9UPQ3
DMAHAVHPNYLDKHE	DNPEP	356	Q9ULA0
PKLIHYHQHNSAGMI	BMX	371	P51813
RLGYHAIPSMSHVHL	APTX	261	Q7Z2E3
VLPVMHESHHAQSEY	CCDC77	331	Q9BR77
PHVRHMAYQLCHALR	CLK3	406	P49761
QHMRDSKHIVVYHRG	CPT1A	326	P50416
HNTPLHYAARHGMNK	ANKIB1	46	Q9P2G1
AKAMALIHLSATHYH	DNHD1	3086	Q96M86
HRHYIQTMQERVHPE	ARHGEF12	461	Q9NZN5
LIRHQMSHDSGKHYE	MECOM	306	Q03112
VHLQTPLHMAIAYNH	ANKFY1	541	Q9P2R3
SHQDHLRKDPYANLM	PATL1	391	Q86TB9
VMPLRASNFHYHELK	KCNMA1	861	Q12791
HHPRVAKYAMENHSL	KIF15	506	Q9NS87
NHEMYDYLLHGHRLK	MERTK	806	Q12866
PPQHYRLDDMAIAHH	RUNX1T1	296	Q06455
RIMDPHYSHKGHLSE	MAPK6	176	Q16659
HLHPRSICMIQKYNH	MSTO1	171	Q9BUK6
SKHKNPYHNLMHAAD	PDE1C	221	Q14123
SHYGHNDDVRNHAMK	PECAM1	661	P16284
RHFELEKHSAPSMVH	NFIL3	361	Q16649
YLNHLEPPVKHMSFH	NPLOC4	151	Q8TAT6
VHYLHSNMIVHRDIK	MAP3K2	471	Q9Y2U5
AAFSANERPRHHHVM	MSL3	221	Q8N5Y2
HAGAAYREVQKLMHH	POU3F1	41	Q03052
YLHTMERPHLHQHVE	LRCH1	301	Q9Y2L9
SHMLHMDPHQRYTAE	RPS6KA6	661	Q9UK32
DIAMAHHFRDAYRHP	CBFA2T3	346	O75081
RMVMAHLVNHLGHYP	RALGAPA2	1376	Q2PPJ7
LHYPQKHMRLFIHNH	PLOD1	311	Q02809
MLHFVMHGQHHKAPF	FA2H	251	Q7L5A8
RQTEHDHYPESRMLH	DYNC2H1	236	Q8NCM8
EALKYHFMPEHRLSH	KLHL28	256	Q9NXS3
KQMLDHFQATPHHGV	DPP9	106	Q86TI2
HHRPGSYLDMKIHLE	CEP126	36	Q9P2H0
RHQLEMPGHYSHLAA	DENND11	176	A4D1U4
HLFPTMPRHNYHKVA	FADS1	386	O60427
IHKHGFFHRDMKPEN	MAK	116	P20794
GLDLRPHNHLQHYDM	KLHDC8A	136	Q8IYD2
RHVYEVPSGKHLMDH	EML5	1846	Q05BV3
SAKLYNGHHHLLMTE	GJA3	311	Q9Y6H8
HRHREKYPHVQMNPH	SALL2	421	Q9Y467
FNAHYNLTRHMPVHT	FEZF2	286	Q8TBJ5
SHHHHQPHKMDLKAY	FOXA2	391	Q9Y261
VRHDQDPGYMHHKFA	PLD6	146	Q8N2A8
KALDYIHHMGYVHRS	STRADA	181	Q7RTN6
IHHMGYVHRSVKASH	STRADA	186	Q7RTN6
RNLHSHYHEAPMTRK	POMT2	421	Q9UKY4
HYHEAPMTRKHYQVT	POMT2	426	Q9UKY4
KHQFVMSRHHDKVPG	NHS	1341	Q6T4R5
LKATYHAHMVIHREN	PRDM15	1031	P57071
AHYNLTRHMPVHTGA	FEZF1	271	A0PJY2
VHLPHNYHIDFEIRM	FASTKD2	596	Q9NYY8
LDDQGHIILHSMHKY	TBX15	226	Q96SF7
HIILHSMHKYQPRVH	TBX15	231	Q96SF7
AEHVRVMHANNPKYV	SELENOO	581	Q9BVL4
HLKQKYPHHASAIMG	KIAA1217	96	Q5T5P2
YPHHASAIMGHQERL	KIAA1217	101	Q5T5P2
YLHSHNMIHRDVKAG	TAOK2	141	Q9UL54
KTPMEMLYHHVHRLN	NPAS3	866	Q8IXF0
RSMEGHAPHHFKLVS	PXYLP1	76	Q8TE99
LAETYPIHMHSQLDH	SLC4A8	616	Q2Y0W8
LSDVHLYTPNHRHLM	METTL22	21	Q9BUU2
YRHMATHSAQKPHQC	PLAGL2	86	Q9UPG8
PADLAHKIHSANHMD	APC	1001	P25054
PFATHYPNHLARHMK	ZNF513	366	Q8N8E2
YPNHLARHMKTHSGE	ZNF513	371	Q8N8E2
RHHRIHSMEKPYVCS	ZNF343	286	Q6P1L6
LHRHVNMYHNPEKPY	ZBTB21	561	Q9ULJ3
TNHHRMHTGEQPYKC	ZNF880	396	Q6PDB4
FLHSYDLKNHMHLHT	ZBTB7B	411	O15156
DLKNHMHLHTGDRPY	ZBTB7B	416	O15156
HDAAFFLSRPMYAHH	THOC2	811	Q8NI27
QHKQDPYIASMEHHT	WDR48	61	Q8TAF3
PHHHYSAIERNNLMR	TRPM6	1706	Q9BX84
KVEAFEHRMYSHPLH	MTREX	796	P42285
EHRMYSHPLHNDPNL	MTREX	801	P42285
GHIILHSMHKYQPRV	TBX18	256	O95935
LLHMHERTHTGEKPY	ZNF799	211	Q96GE5
GHLILHSMHKYQPRI	TBX6	206	O95947
HSMHKYQPRIHLVRA	TBX6	211	O95947
IMQLHHSKHHAAYVN	SOD2	46	P04179
YMNKHGIVHRALSPH	TBCK	106	Q8TEA7
HLIEHMRLHSGEKPY	ZEB1	946	P37275
YLMPHLNRHQKTHSG	ZIM2	366	Q9NZV7
LLQHHMIHTGERPYE	ZNF264	246	O43296
RSYLMQHHPIHTGEK	ZNF550	271	Q7Z398
HNYDLKNHMRIHTGV	ZBTB7C	431	A1YPR0
HLQIHMRVHTGEKPY	ZNF664	101	Q8N3J9
LLHMHERTHTGEKPY	ZNF443	211	Q9Y2A4
HHRIHTGEKPYQCSM	ZKSCAN3	416	Q9BRR0
YGTEDHHKNLRNHMV	ZNF57	91	Q68EA5
MPLRDKYCQTDHHHH	ZNF800	1	Q2TB10
HQMETHYRVHTGEKP	ZBTB32	386	Q9Y2Y4
HGHIILNSMHKYQPR	TBX20	216	Q9UMR3
HLSRHMNSHVKEKPY	ZNF597	226	Q96LX8
AFNYSTHLKIHMRIH	ZNF426	456	Q9BUY5
SVSHLISYHMDNHLP	SHC1	551	P29353
LHNHHRVHTGEMPYK	ZNF285	331	Q96NJ3
VFRHLENYANHLKMH	ZBTB26	281	Q9HCK0
AFAHNYDLKNHMRVH	ZBTB7A	446	O95365
HRHERSHMGEKAYQC	ZNF439	286	Q8NDP4
DLVNEAKRYHMLPHA	KLHL29	551	Q96CT2