Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ROR2 PTK7

1.07e-0365152GO:0004714
GeneOntologyMolecularFunctioncoreceptor activity

ROR2 PTK7

1.31e-0372152GO:0015026
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ROR2 PTK7

1.81e-0385152GO:0019199
GeneOntologyBiologicalProcesssynapse organization

PCDHB6 IL1RAPL2 ROR2 PTK7 SHANK2

9.06e-05685155GO:0050808
HumanPhenoUmbilical hernia

FGD1 ROR2 MYLK

2.15e-0430633HP:0001537
HumanPhenoInguinal hernia

FGD1 ROR2 MYLK

2.28e-0431233HP:0000023
HumanPhenoAbnormal umbilicus morphology

FGD1 ROR2 MYLK

2.30e-0431333HP:0001551
HumanPhenoAbnormality of external features of the abdomen

FGD1 ROR2 MYLK

2.60e-0432633HP:0001462
HumanPhenoShort 5th finger

FGD1 ROR2

4.62e-046432HP:0009237
HumanPhenoAplasia/Hypoplasia of the 5th finger

FGD1 ROR2

4.92e-046632HP:0006262
HumanPhenoAplasia/Hypoplasia involving the vertebral column

FGD1 ROR2

5.86e-047232HP:0008518
HumanPhenoVertebral fusion

FGD1 ROR2

6.19e-047432HP:0002948
HumanPhenoAbnormal sternum morphology

FGD1 ROR2 MYLK

8.01e-0447433HP:0000766
HumanPhenoHernia of the abdominal wall

FGD1 ROR2 MYLK

9.75e-0450633HP:0004299
HumanPhenoThoracoabdominal wall defect

FGD1 ROR2 MYLK

1.00e-0351133HP:0100656
HumanPhenoAbdominal wall defect

FGD1 ROR2 MYLK

1.00e-0351133HP:0010866
HumanPhenoMulticystic kidney dysplasia

ROR2 MYLK

1.09e-039832HP:0000003
HumanPhenoAbnormality of the abdominal wall

FGD1 ROR2 MYLK

1.32e-0356033HP:0004298
HumanPhenoHernia

FGD1 ROR2 MYLK

1.54e-0358933HP:0100790
HumanPhenoShort palm

FGD1 ROR2

1.57e-0311832HP:0004279
HumanPhenoSmall hand

FGD1 ROR2

1.68e-0312232HP:0200055
DomainIg-like_fold

NFAT5 IL1RAPL2 ROR2 PTK7 SHANK2 MYLK

1.07e-05706156IPR013783
Domain-

NFAT5 IL1RAPL2 ROR2 PTK7 MYLK

1.24e-046631552.60.40.10
DomainIg_sub

IL1RAPL2 ROR2 PTK7 MYLK

2.85e-04421154IPR003599
DomainIG

IL1RAPL2 ROR2 PTK7 MYLK

2.85e-04421154SM00409
DomainI-set

ROR2 PTK7 MYLK

4.31e-04190153PF07679
DomainIg_I-set

ROR2 PTK7 MYLK

4.31e-04190153IPR013098
DomainIG_LIKE

IL1RAPL2 ROR2 PTK7 MYLK

5.11e-04491154PS50835
DomainIg-like_dom

IL1RAPL2 ROR2 PTK7 MYLK

5.60e-04503154IPR007110
DomainIg_sub2

ROR2 PTK7 MYLK

8.00e-04235153IPR003598
DomainIGc2

ROR2 PTK7 MYLK

8.00e-04235153SM00408
DomainTyrKc

ROR2 PTK7

2.21e-0388152SM00219
DomainTyr_kinase_cat_dom

ROR2 PTK7

2.21e-0388152IPR020635
DomainTRYPSIN_SER

TPSAB1 TPSB2

2.31e-0390152IPR033116
DomainPROTEIN_KINASE_TYR

ROR2 PTK7

2.68e-0397152PS00109
DomainTyr_kinase_AS

ROR2 PTK7

2.68e-0397152IPR008266
DomainTRYPSIN_HIS

TPSAB1 TPSB2

3.02e-03103152IPR018114
DomainTRYPSIN_SER

TPSAB1 TPSB2

3.19e-03106152PS00135
DomainTRYPSIN_HIS

TPSAB1 TPSB2

3.25e-03107152PS00134
DomainPeptidase_S1A

TPSAB1 TPSB2

3.62e-03113152IPR001314
DomainTRYPSIN_DOM

TPSAB1 TPSB2

3.74e-03115152PS50240
DomainTryp_SPc

TPSAB1 TPSB2

3.87e-03117152SM00020
DomainTrypsin

TPSAB1 TPSB2

4.14e-03121152PF00089
DomainTrypsin_dom

TPSAB1 TPSB2

4.14e-03121152IPR001254
DomainPeptidase_S1_PA

TPSAB1 TPSB2

4.27e-03123152IPR009003
DomainPkinase_Tyr

ROR2 PTK7

4.69e-03129152PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

ROR2 PTK7

5.34e-03138152IPR001245
DomainProt_kinase_dom

ROR2 PTK7 MYLK

6.42e-03489153IPR000719
DomainPROTEIN_KINASE_DOM

ROR2 PTK7 MYLK

6.56e-03493153PS50011
DomainKinase-like_dom

ROR2 PTK7 MYLK

8.52e-03542153IPR011009
Pubmed

Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft.

TPSAB1 TPSB2

1.74e-07215210391906
Pubmed

The human mast cell tryptase tetramer: a fascinating riddle solved by structure.

TPSAB1 TPSB2

1.74e-07215210708850
Pubmed

Cloning and characterization of a second complementary DNA for human tryptase.

TPSAB1 TPSB2

1.74e-0721522203827
Pubmed

Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels.

TPSAB1 TPSB2

1.74e-07215217449330
Pubmed

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia.

TPSAB1 TPSB2

1.74e-07215231337736
Pubmed

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore.

TPSAB1 TPSB2

1.74e-0721529521329
Pubmed

The structure of the human betaII-tryptase tetramer: fo(u)r better or worse.

TPSAB1 TPSB2

1.74e-07215210500112
Pubmed

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family.

TPSAB1 TPSB2

1.74e-0721522187193
Pubmed

Characterization of a tryptase mRNA expressed in the human basophil cell line KU812.

TPSAB1 TPSB2

1.74e-0721528434231
Pubmed

Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog.

TPSAB1 TPSB2

1.74e-07215210898108
Pubmed

Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase.

TPSAB1 TPSB2

1.74e-07215215567416
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

KIF13A TPSAB1 TPSB2 SHANK2 MYLK

2.04e-0732915517474147
Pubmed

Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations.

TPSAB1 TPSB2

5.21e-07315219748655
Pubmed

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

TPSAB1 TPSB2

5.21e-0731529920877
Pubmed

Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.

TPSAB1 TPSB2

1.73e-06515210843716
Pubmed

New developments in the genetics and activation of mast cell proteases.

TPSAB1 TPSB2

2.60e-06615212217407
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

IL1RAPL2 ROR2 PTK7 SHANK2

2.58e-0542015428065597
Pubmed

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment.

ROR2 PTK7

6.06e-052715230516471
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

ROR2 PTK7

1.34e-044015230898150
Pubmed

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.

ROR2 PTK7

3.45e-046415224431302
Pubmed

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.

TPSAB1 TPSB2

3.78e-046715222046132
InteractionTPSAB1 interactions

TPSAB1 TPSB2

4.68e-0514152int:TPSAB1
InteractionTPSB2 interactions

TPSAB1 TPSB2

7.86e-0518152int:TPSB2
Cytoband16p13.3

TPSAB1 TPSB2

2.82e-0324415216p13.3
CytobandEnsembl 112 genes in cytogenetic band chr16p13

TPSAB1 TPSB2

8.33e-03426152chr16p13
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ROR2 PTK7 MYLK

1.44e-04161123593
GeneFamilyReceptor Tyrosine Kinases|CD molecules

ROR2 PTK7

3.11e-0440122321
GeneFamilyImmunoglobulin like domain containing

IL1RAPL2 PTK7

6.97e-03193122594
CoexpressionAtlasgeo_heart_top-relative-expression-ranked_500_k-means-cluster#5

TPSAB1 TPSB2

1.30e-058152geo_heart_500_K5
CoexpressionAtlasgeo_heart_top-relative-expression-ranked_1000_k-means-cluster#3

TPSAB1 TPSB2

7.08e-0518152geo_heart_1000_K3
CoexpressionAtlasPP_MEG_top-relative-expression-ranked_500_k-means-cluster#1

TPSAB1 ARHGAP30 TPSB2

1.54e-04152153PP_MEG_500_K1
CoexpressionAtlasfacebase_RNAseq_e9.5_OlfPlac_2500_K1

TOX2 MYLK

1.87e-0429152facebase_RNAseq_e9.5_OlfPlac_2500_K1
CoexpressionAtlasPP_MEG_top-relative-expression-ranked_500

TPSAB1 ARHGAP30 TPSB2 MYLK

3.22e-04494154PP_MEG_500
CoexpressionAtlasPP_HSC_top-relative-expression-ranked_500_k-means-cluster#5

TPSAB1 ARHGAP30 TPSB2

3.92e-04209153PP_HSC_500_K5
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#3

TPSAB1 TPSB2

5.16e-0448152Arv_SC_fibroblast_1000_K3
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#5

TPSAB1 TPSB2

5.60e-0450152Arv_SC-HD_1000_K5
CoexpressionAtlasPP_GMP_top-relative-expression-ranked_500_k-means-cluster#3

TPSAB1 ARHGAP30 TPSB2

6.53e-04249153PP_GMP_500_K3
ToppCelllymphoid-B_cell-pro-B|B_cell / Lineage, cell class and subclass

TPSAB1 TPSB2 ROR2 MYLK

2.72e-07172154da1e2e54f442f5c2032c857c4812e9060f2053cd
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDHB6 ROR2 PTK7 MYLK

3.97e-07189154f7e2ee5047792ab9ef6472fa88e2d193cdea6fa0
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-basophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 TPSB2 PTK7

1.60e-05150153408b7c2c3a42f5455c8c26a83d9e366a1c8d5ecc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 IL1RAPL2 ROR2

1.64e-0515115310da94037225a71844281ddcb395072250a78094
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF13A IL1RAPL2 MYLK

1.67e-051521530cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF13A IL1RAPL2 MYLK

1.67e-05152153ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PCDHB6 ROR2 MYLK

2.10e-05164153e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

TOX2 IL1RAPL2 MYLK

2.13e-05165153f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD1 TPSB2 PTK7

2.25e-05168153b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPSAB1 ARHGAP30 TPSB2

2.29e-05169153bca5322880c09b78ef10d9dda6420a80c1ba7e62
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IL1RAPL2 TPSAB1 TPSB2

2.29e-05169153f47c4fbdc2a38745ec1b35104b85121c1413875a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPSAB1 ARHGAP30 TPSB2

2.33e-05170153c4f00c1acde1d3b521101e469101d10fd257653e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPSAB1 ARHGAP30 TPSB2

2.33e-05170153d3c1edaf0190d8927578043c372dba7477e75e14
ToppCellBronchial_Biopsy-Immune-Mast_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

TPSAB1 ARHGAP30 TPSB2

2.42e-05172153c477008444d2d71071177807870d7455e90c2fad
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IL1RAPL2 ROR2 MYLK

2.50e-05174153df5664da3b93c233509781429a9c6d7edf1b8944
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IL1RAPL2 ROR2 PTK7

2.54e-05175153030f93af5a96848b9118e2a8116e19ddae438d92
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PCDHB6 ROR2 MYLK

2.63e-05177153b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCellcontrol-Others-CD34+_GATA2+_cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TPSAB1 TPSB2 PTK7

2.68e-051781532120bd3e099b0b271bf079db9827a2f3eee2f909
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPSAB1 TPSB2 PTK7

2.72e-051791532f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCellCOVID-19_Mild-Hematopoietic_SC-HSPC|COVID-19_Mild / Disease group, lineage and cell class

TPSAB1 TPSB2 PTK7

2.72e-0517915319fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPSAB1 TPSB2 PTK7

2.72e-051791534bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPSAB1 TPSB2 PTK7

2.72e-051791533e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCellCOVID-19_Mild-Hematopoietic_SC|COVID-19_Mild / Disease group, lineage and cell class

TPSAB1 TPSB2 PTK7

2.72e-0517915350a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL2 ROR2 SHANK2

2.77e-05180153023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPSAB1 ARHGAP30 TPSB2

2.77e-051801531c5515f29ead129bee3b4ca27799796956811a39
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ROR2 PTK7 MYLK

2.81e-0518115325915e2500430a902db37d79a749ce2990b69810
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TPSAB1 TPSB2 PTK7

2.81e-0518115354a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TPSAB1 TPSB2 PTK7

2.81e-051811535b84625b1d3737708001b64f6da9360330d39a27
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TPSAB1 TPSB2 PTK7

2.81e-05181153e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCellCOVID-19_Severe-Hematopoietic_SC-HSPC|COVID-19_Severe / Disease group, lineage and cell class

TPSAB1 TPSB2 PTK7

2.91e-051831534146b1c0e5f76d25226745abfa28f77127a444fc
ToppCellCOVID-19_Severe-Hematopoietic_SC|COVID-19_Severe / Disease group, lineage and cell class

TPSAB1 TPSB2 PTK7

2.91e-0518315392aab7ce65aca17988bc2add4ff9fb8384e2c21b
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IL1RAPL2 ROR2 MYLK

2.91e-05183153bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCellPBMC-Severe-Hematopoietic-HSPC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPSAB1 TPSB2 PTK7

2.95e-05184153a6169613c6493b947a176493f542368bfa935dab
ToppCellPBMC-Severe-Hematopoietic-HSPC-HSPC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPSAB1 TPSB2 PTK7

2.95e-05184153cc01c19180861f491a8dc16d60fabd1215fc4525
ToppCellIPF-Myeloid-Mast|Myeloid / Disease state, Lineage and Cell class

TPSAB1 TPSB2 ROR2

2.95e-051841537326a16d7d3ae41b8c9d2beaec7f977b374f3469
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

ROR2 PTK7 MYLK

2.95e-051841530b336489c10e8c3c957795dd845454f03404382b
ToppCellPBMC-Severe-Hematopoietic-HSPC-HSPC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TPSAB1 TPSB2 PTK7

2.95e-05184153492c680f0769ba4e651d09c2e8e5d5d271ed08aa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 IL1RAPL2 ROR2

3.15e-05188153e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

TPSAB1 TPSB2 SHANK2

3.15e-05188153186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TPSAB1 ARHGAP30 TPSB2

3.15e-05188153ab95a97db1a84bf3e53a4616a83ee81a6ce5ec12
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDHB6 ROR2 MYLK

3.20e-0518915363449d9f1e78ff2bc8786eb88a0d177fe30c7f4d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 IL1RAPL2 ROR2

3.25e-0519015311d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

ROR2 PTK7 MYLK

3.25e-05190153645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFAT5 IL1RAPL2 ROR2

3.25e-05190153078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 ARHGAP30 TPSB2

3.30e-0519115314b11244c330cc4fe897253aaaf0df80caa01a55
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

MAP1LC3C ROR2 MYLK

3.30e-051911531726add3f392a061536b7aff72ba84303f4a0b1f
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 ARHGAP30 TPSB2

3.30e-0519115347f20686001f945bc31d5a0b974958e4009edb34
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

MAP1LC3C ROR2 MYLK

3.30e-05191153e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ROR2 PTK7 MYLK

3.35e-0519215367e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

TOX2 ROR2 MYLK

3.40e-05193153acad568621ed677031797b8c2e34dafea798d681
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TOX2 ROR2 MYLK

3.46e-05194153e93de9428c986b8943fc169258847c650cfab0e5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TOX2 ROR2 MYLK

3.46e-05194153011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 ARHGAP30 TPSB2

3.46e-051941539116451614431e3cf9bd7d4d626bf4bd23420e36
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_Granulocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TPSAB1 ARHGAP30 TPSB2

3.46e-0519415385c5d07189eb7bb413f708a3ca40de08af3cb106
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 ARHGAP30 TPSB2

3.46e-05194153bf7bf75bbc2035be25d3605e6a1a59e6bc573be7
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

TOX2 ROR2 MYLK

3.51e-0519515361c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

TOX2 ROR2 MYLK

3.51e-05195153603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ROR2 PTK7 MYLK

3.62e-05197153f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellproximal-3-Hematologic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 ARHGAP30 TPSB2

3.73e-05199153dff0ca657bfb42083000e3d0125b54480b034a93
ToppCellwk_15-18-Mesenchymal-Fibroblast-Alveolar_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TOX2 PTK7 MYLK

3.73e-051991536bce8e65859a35cfea1c210f9c9765952d492ed2
ToppCellproximal-Hematologic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TPSAB1 ARHGAP30 TPSB2

3.73e-05199153183e388ac837585c50fed1189496167c9e61511e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TOX2 ROR2 MYLK

3.79e-05200153e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TOX2 ROR2 MYLK

3.79e-05200153f692b602bc989d35c9162e73dda813dbef8d5267
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

TPSAB1 TPSB2

5.12e-0532152b2d87153b4aefefd7b5e31ea67aa43e5f599e734
ToppCellTCGA-Pancreas-Primary_Tumor|TCGA-Pancreas / Sample_Type by Project: Shred V9

TPSAB1 TPSB2

5.12e-0532152f5bcaacbddfb85439ebf5908762bf39cb72b727c
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Thalamus / BrainAtlas - Mouse McCarroll V32

TPSAB1 TPSB2

6.20e-04111152567e5ac2c78d45db207067f0f152bb24ed048c50
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Thalamus / BrainAtlas - Mouse McCarroll V32

TPSAB1 TPSB2

6.20e-04111152d1ec8e8e9adb11511b4ef363cc6f99286e2cc842
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Thalamus / BrainAtlas - Mouse McCarroll V32

TPSAB1 TPSB2

6.20e-04111152fd7aa25e83a0d762969e3966a658652da40c490e
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TPSAB1 TPSB2

6.20e-041111521847dde68d349114286bc3317be6339666df4aa2
ToppCellThalamus-Hematopoietic-MACROPHAGE|Thalamus / BrainAtlas - Mouse McCarroll V32

TPSAB1 TPSB2

6.20e-04111152d48561078c387ac856c1c30e3d7a3e75ebde942e
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Thalamus / BrainAtlas - Mouse McCarroll V32

TPSAB1 TPSB2

6.20e-04111152a1b7940c6fa0e5a58aa4798b604469d79f33fa44
ToppCellParenchymal-10x5prime-Immune_Myeloid-Myeloid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 TPSB2

6.89e-04117152f0c738b6b850733f9af68704172554177a1c1198
ToppCellParenchymal-10x5prime-Immune_Myeloid-Myeloid-Megakaryocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TPSAB1 TPSB2

6.89e-04117152b5cb9d69ddd42331134f7e4bd51bd1c31030893c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TPSAB1 TPSB2

7.48e-04122152032b5da8befcb1a159245f8d0c67f91795883ee0
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-basophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 TPSB2

7.85e-04125152dec39707624529689f68dd46f910a71db5e91ab2
ToppCellControl-dn_T|Control / Disease condition and Cell class

TOX2 PTK7

8.23e-04128152e492684b2eafc6c91d2e7d7b9f54defb6642069e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTK7 MYLK

8.36e-041291526abdba987c8528f7cb90b32dc01796e02c7352c9
ToppCellMyeloid-D_(Mast_cell)|World / shred on cell class and cell subclass (v4)

TPSAB1 TPSB2

8.49e-04130152574e262eb4ed2d69c3da68be061cebac9fefc29e
ToppCellFetal_29-31_weeks-Immune-mast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TPSAB1 TPSB2

9.01e-041341521d6e74612fd91a2ef9d14bf77262b2d08e1052ca
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TPSAB1 TPSB2

9.15e-0413515216ae3e31af2430ba5be1523fc18d491974940576
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 ROR2

9.42e-041371526d90da42dcc06aa895f920218055068f3c76d57d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK7 SHANK2

9.55e-041381526b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCellCOVID-19-Mast_cells-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

TPSAB1 TPSB2

9.97e-041411520fc06c2325249aa4ae65c0ace1ec3f953372f2e4
ToppCellCOVID-19_Severe-dn_T|COVID-19_Severe / Disease condition and Cell class

TOX2 PTK7

1.01e-031421522008033881b9e1b20926c3508d6ebdb6f1a1528f
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDHB6 MYLK

1.03e-0314315239060dc1d87505a16e2df95140087c731f099570
ToppCellfacs-Trachea-3m-Hematologic-myeloid-granulocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TPSAB1 TPSB2

1.05e-03145152e381fd90fdaf2ff8c0d2584b6e0a4506418c9593
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-dnT|Multiple_Sclerosis / Disease, Lineage and Cell Type

TOX2 PTK7

1.05e-03145152d24894be1d6664df9a6af8ea33f2ffce0c718635
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TOX2 IL1RAPL2

1.05e-031451528b13b576fd2e6e33ccb146860a91a53cee0cdd4d
ToppCellSevere-Myeloid-Mast-|Severe / Condition, Lineage, Cell class and cell subclass

TPSAB1 TPSB2

1.05e-03145152ce307d45425a5191882078f049f85477eec40b69
ToppCellSevere-Myeloid-Mast|Severe / Condition, Lineage, Cell class and cell subclass

TPSAB1 TPSB2

1.05e-03145152e0bfd2ffdbd6c197ef0a04e983396ebd87ef7127
ToppCellChildren_(3_yrs)-Immune-mast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TPSAB1 TPSB2

1.07e-03146152f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL2 ROR2

1.08e-0314715264fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCell356C-Myeloid-Mast_cell-|356C / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 TPSB2

1.10e-0314815218511ba10765eda937c5a710626361f7e6b9b321
ToppCellASK454-Immune|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

TPSAB1 ARHGAP30

1.10e-031481521076c69bf2a5e4557aa35643fd9bd86e8610815b
ToppCell356C-Myeloid-Mast_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

TPSAB1 TPSB2

1.10e-031481521668d8a9e680da335362744f36b05446c499347e
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 TPSB2

1.11e-031491526a28dd4530ed411747fdfe743db138a1b5547ed7
ToppCellfacs-Trachea-nan-3m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPSAB1 TPSB2

1.11e-031491529c4837aa63e46382ff45a41c72beb5722b3ada19
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TPSAB1 TPSB2

1.11e-03149152c9334f319a0c943268e54b6f0c9446736172c3a9
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TPSAB1 TPSB2

1.11e-03149152e99b7cd3728ce76b365526734c2e7f845b2e62c8
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-7|TCGA-Bladder / Sample_Type by Project: Shred V9

MAP1LC3C TOX2

1.13e-031501523ab17045b2c43bb4f0ebba6aa0cfb22e076a24f9
ComputationalGenes in the cancer module 199.

ROR2 PTK7 MYLK

1.16e-055793MODULE_199
ComputationalResponse to DNA damage.

ROR2 PTK7 MYLK

4.03e-0418793MODULE_244
ComputationalRTK signaling.

PTK7 MYLK

6.33e-044692MODULE_259
ComputationalGenes in the cancer module 85.

ROR2 PTK7

7.78e-045192MODULE_85
ComputationalGenes in the cancer module 138.

ROR2 MYLK

2.25e-038792MODULE_138
Drugthymidine glycol monophosphate

TPSAB1 TPSB2

1.21e-063152CID000165415
DrugBrunfelsamidine

TPSAB1 TPSB2

2.43e-064152CID005281683
DrugAttpsa

TPSAB1 TPSB2

6.07e-066152CID005487511
Drugioxaglate

TPSAB1 TPSB2

8.49e-067152CID000003742
DrugTelebrix

TPSAB1 TPSB2

8.49e-067152CID000034536
Drugdaphnodorin C

TPSAB1 TPSB2

1.45e-059152CID000072428
DrugAC1L1DDL

TPSAB1 TPSB2 PTK7

1.78e-0579153CID000002304
Drug1c5s

TPSAB1 TPSB2

1.82e-0510152CID000444753
DrugAC1NUP69

TPSAB1 TPSB2

1.82e-0510152CID005487154
DrugZ-ala-ala-lys-mna

TPSAB1 TPSB2

2.22e-0511152CID005486901
Drugpimaradiene

TPSAB1 TPSB2

2.22e-0511152CID000440909
Drugdaphnodorin A

TPSAB1 TPSB2

2.22e-0511152CID000072426
DrugAC1NSU64

TPSAB1 TPSB2

2.22e-0511152CID005316303
Drugmethylhistamine

TPSAB1 TPSB2

2.22e-0511152CID000000912
Drugbis(5-amidino-2-benzimidazolyl)methane

TPSAB1 TPSB2

2.66e-0512152CID000002386
DrugNSC-648146

TPSAB1 TPSB2

2.66e-0512152CID000372649
Drug4-amidinophenylpyruvic acid

TPSAB1 TPSB2

2.66e-0512152CID000151496
DrugElocom

TPSAB1 TPSB2

2.66e-0512152CID000123620
DrugZ-ARR-AFC

TPSAB1 TPSB2

3.15e-0513152CID000125067
DrugNk3201

TPSAB1 TPSB2

3.15e-0513152CID000213050
DrugABPH

TPSAB1 TPSB2

3.67e-0514152CID000092377
Drug[(E)-ethylideneamino]thiourea

PTK7 SHANK2

4.23e-0515152CID009604626
DrugAC1L9K4M

TPSAB1 TPSB2

4.23e-0515152CID000446820
DrugFdTTP

TPSAB1 TPSB2

4.23e-0515152CID000162005
Drug5 alpha-androstan-3-one

TPSAB1 TPSB2

4.84e-0516152CID000102028
Drugthymidine glycol

TPSAB1 TPSB2

4.84e-0516152CID003035041
Drug(E)-4-aminohex-4-enoic acid

TPSAB1 TPSB2

4.84e-0516152CID005288385
Drugthiopental

IL1RAPL2 TPSAB1 TPSB2

5.05e-05112153CID003000715
DrugEpiamastatin hydrochloride

TPSAB1 TPSB2 PTK7

5.46e-05115153CID000003237
Drugmethylimidazoleacetic acid

TPSAB1 TPSB2

5.48e-0517152CID000075810
DrugH 17

TPSAB1 TPSB2

5.48e-0517152CID000476867
Drug2-azetidinone

TPSAB1 TPSB2

6.16e-0518152CID000136721
DrugNSC49103

TPSAB1 TPSB2

7.64e-0520152CID000005251
DrugA80a

TPSAB1 TPSB2

7.64e-0520152CID005487000
Drugatracurium besylate

TPSAB1 TPSB2

9.29e-0522152CID000047320
DrugMedroxyprogesterone Acetate

FGD1 TOX2 PTK7 MYLK

9.87e-05389154ctd:D017258
Drugtryptophanyl-5'AMP

TPSAB1 TPSB2

1.02e-0423152CID000446202
DrugKinetensin

TPSAB1 TPSB2

1.02e-0423152CID000147043
DrugPL 0

TPSAB1 TPSB2

1.11e-0424152CID000016157
DrugAC1L8VEV

TPSAB1 TPSB2

1.11e-0424152CID000433433
DrugCAS 79547-78-7

TPSAB1 TPSB2

1.20e-0425152CID000003915
DrugCAS 83919-23-7

TPSAB1 TPSB2

1.30e-0426152CID000004240
Drug2-methylundecanal

TPSAB1 TPSB2

1.41e-0427152CID000061031
DrugB Ba

TPSAB1 TPSB2

1.63e-0429152CID000001499
Drug5(G)-TASP

PTK7 MYLK

1.63e-0429152CID000488931
Drugbutter yellow

TPSAB1 TPSB2

1.74e-0430152CID000007340
DrugcKP

TPSAB1 TPSB2

1.74e-0430152CID005494415
DrugAC1NS1E4

TPSAB1 TPSB2

1.86e-0431152CID005326963
Drug1,1/t,t

TPSAB1 TPSB2

1.86e-0431152CID000444372
DruguPA inhibitor

TPSAB1 TPSB2

1.99e-0432152CID000001746
Drugatracurium

TPSAB1 TPSB2

2.38e-0435152CID000047319
DrugCI-U

TPSAB1 TPSB2

2.38e-0435152CID000004357
DrugPropoxycaine hydrochloride [550-83-4]; Down 200; 12uM; PC3; HT_HG-U133A

FGD1 U2SURP PTK7

2.49e-041921537155_DN
DrugAG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A

FGD1 SHANK2 MYLK

2.53e-041931535904_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; HL60; HT_HG-U133A

IL1RAPL2 ROR2 MYLK

2.53e-041931533015_UP
DrugEquilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A

KIF13A NFAT5 FGD1

2.57e-041941533377_DN
DrugAztreonam [78110-38-0]; Down 200; 9.2uM; PC3; HT_HG-U133A

NFAT5 U2SURP SHANK2

2.57e-041941532118_DN
DrugCyproterone acetate [427-51-0]; Up 200; 9.6uM; HL60; HT_HG-U133A

KIF13A FGD1 SHANK2

2.61e-041951536124_UP
DrugMethacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

NFAT5 FGD1 PTK7

2.61e-041951533452_UP
Drug0173570-0000 [211245-44-2]; Down 200; 1uM; PC3; HT_HG-U133A

FGD1 U2SURP SHANK2

2.65e-041961537391_DN
DrugMebeverine hydrochloride [2753-45-9]; Down 200; 8.6uM; PC3; HT_HG-U133A

FGD1 U2SURP MYLK

2.65e-041961537147_DN
DrugPHA-00851261E [724719-49-7]; Down 200; 1uM; MCF7; HT_HG-U133A

NFAT5 IL1RAPL2 SHANK2

2.65e-041961533857_DN
DrugSulfadimethoxine [122-11-2]; Up 200; 12.8uM; PC3; HT_HG-U133A

KIF13A IL1RAPL2 MYLK

2.65e-041961537400_UP
DrugTriamterene [396-01-0]; Down 200; 15.8uM; PC3; HT_HG-U133A

FGD1 IL1RAPL2 MYLK

2.65e-041961531819_DN
DrugKawain [500-64-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A

KIF13A NFAT5 MYLK

2.69e-041971534693_DN
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

IL1RAPL2 SHANK2 MYLK

2.69e-041971532654_UP
DrugHarmol hydrochloride monohydrate [40580-83-4]; Up 200; 15.8uM; HL60; HG-U133A

NFAT5 FGD1 U2SURP

2.69e-041971531750_UP
DrugPimozide [2062-78-4]; Down 200; 8.6uM; PC3; HT_HG-U133A

FGD1 PTK7 MYLK

2.69e-041971537132_DN
Drugtrifluoperazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A

U2SURP PTK7 MYLK

2.69e-041971531224_DN
DrugAlthiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A

KIF13A FGD1 MYLK

2.73e-041981536089_DN
DrugThiocolchicoside [602-41-5]; Down 200; 7uM; PC3; HT_HG-U133A

NFAT5 FGD1 SHANK2

2.77e-041991535095_DN
DrugLeucomisine [17946-87-1]; Up 200; 16.2uM; HL60; HT_HG-U133A

FGD1 ROR2 SHANK2

2.77e-041991536125_UP
DrugFlurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A

FGD1 IL1RAPL2 MYLK

2.77e-041991536472_UP
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; MCF7; HT_HG-U133A

KIF13A NFAT5 IL1RAPL2

2.77e-041991531470_UP
Drugtele-methylhistamine

TPSAB1 TPSB2

2.81e-0438152CID000003614
DrugGPGR

TPSAB1 TPSB2

2.81e-0438152CID000485268
Drug2g6p

TPSAB1 TPSB2

2.81e-0438152CID002740174
DrugDrofenine hydrochloride [548-66-3]; Down 200; 11.4uM; PC3; HT_HG-U133A

FGD1 PTK7 SHANK2

2.81e-042001537129_DN
DrugClidinium bromide [3485-62-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A

ROR2 SHANK2 MYLK

2.81e-042001536837_UP
DrugDB04623

TPSAB1 TPSB2

2.96e-0439152CID005459358
Drugisocoumarin

TPSAB1 TPSB2

2.96e-0439152CID000068108
Drugethylene oxide

TPSAB1 TPSB2

2.96e-0439152CID000006354
DrugNSC89634

TPSAB1 TPSB2

2.96e-0439152CID000070877
Drugcromoglicate

TPSAB1 TPSB2

3.27e-0441152CID000027686
DrugPhe-pro-arg

TPSAB1 TPSB2

3.27e-0441152CID000133189
DrugNPGB

TPSAB1 TPSB2

3.27e-0441152CID000030744
DrugAC1L3S1M

TPSAB1 TPSB2

3.27e-0441152CID000121071
DrugDMAPP

TPSAB1 TPSB2

3.77e-0444152CID000000647
DrugAC1Q6RZL

TPSAB1 TPSB2

4.31e-0447152CID000001144
DrugAPMSF

TPSAB1 TPSB2

4.49e-0448152CID000001719
Drug2D7

TPSAB1 TPSB2

4.68e-0449152CID005327103
Drughexitol

NFAT5 TPSAB1 TPSB2

4.97e-04243153CID000000453
Drugisobutyrate

TPSAB1 TPSB2

5.07e-0451152CID000006590
Drugbisphenol F

TPSAB1 TPSB2

5.07e-0451152CID000012111
Drugnedocromil sodium

TPSAB1 TPSB2

5.27e-0452152CID000050294
Drugcetirizine

TPSAB1 TPSB2

5.48e-0453152CID000002678
Drugloratadine

TPSAB1 TPSB2

6.11e-0456152CID000003957
Drugketotifen

TPSAB1 TPSB2

6.33e-0457152CID000003827
DrugAC1LTNWX

TPSAB1 TPSB2

6.56e-0458152CID001536427
Diseasetryptase beta-2 measurement

TPSAB1 TPSB2

8.67e-069152EFO_0008306
Diseaseurticaria

TPSAB1 TPSB2

4.56e-0520152EFO_0005531
Diseasebasophil measurement

TPSAB1 TPSB2

4.20e-0460152EFO_0803539
DiseaseAdenocarcinoma of large intestine

ROR2 PTK7

1.07e-0396152C1319315
DiseaseStuttering

TOX2 ROR2

2.35e-03143152HP_0025268
Diseaseempathy measurement

ROR2 MYLK

3.30e-03170152EFO_0009183
Diseaseurate measurement

NFAT5 U2SURP SHANK2

9.63e-03895153EFO_0004531

Protein segments in the cluster

PeptideGeneStartEntry
PPKAAMPPQIIQFPE

MYLK

1231

Q15746
SPKQPPPNMIFNPNQ

NFAT5

1281

O94916
MPPPQKIPSVRPFKQ

MAP1LC3C

1

Q9BXW4
SVPVVPPKPQFAKMP

ARHGAP30

936

Q7Z6I6
EFKFLKPIMPNFPPQ

PCDHB6

761

Q9Y5E3
PQPPKFFKPLMPVKE

KIF13A

1461

Q9H1H9
PPFPLKQVKVPIMEN

TPSAB1

171

Q15661
PPFPLKQVKVPIMEN

TPSB2

171

P20231
TDKPPKPLFPMENQP

IL1RAPL2

236

Q9NP60
GPKPQVPPKPSYLQM

FGD1

156

P98174
QKAPPFPQPQFIPMK

ROR2

791

Q01974
FPQPQFIPMKGQIRP

ROR2

796

Q01974
GQAFMVDKPPVPPKP

SHANK2

1536

Q9UPX8
LKNPNAPMLPPPKNK

U2SURP

391

O15042
NPPAKMLPPKQPMYA

TOX2

316

Q96NM4
KLKFTPPPQPQQCME

PTK7

501

Q13308