Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

2.90e-0521082GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

2.90e-0521082GO:0044017
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP KAT7 EP300

6.68e-05151083GO:0010484
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

8.66e-0531082GO:0043993
GeneOntologyMolecularFunctionprocollagen-proline 3-dioxygenase activity

P3H2 P3H1

8.66e-0531082GO:0019797
GeneOntologyMolecularFunctionpeptidyl-proline 3-dioxygenase activity

P3H2 P3H1

1.73e-0441082GO:0031544
GeneOntologyMolecularFunctionneuroligin family protein binding

NRXN1 NRXN2

2.87e-0451082GO:0097109
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

TET2 P3H2 P3H1 KDM2B

4.25e-04651084GO:0016706
GeneOntologyMolecularFunctiontransition metal ion binding

TET2 FLG FBXO40 CP FBXO11 GRIN2B CREBBP ZKSCAN5 KAT7 ACE2 AEBP1 P3H2 P3H1 PRICKLE2 KDM2B EP300

6.45e-04118910816GO:0046914
GeneOntologyMolecularFunctionprocollagen-proline dioxygenase activity

P3H2 P3H1

7.94e-0481082GO:0019798
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN1 GRIN2B

7.94e-0481082GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN1 GRIN2B

7.94e-0481082GO:0004972
GeneOntologyMolecularFunctionacyltransferase activity

CUL4A FBXO40 RGPD1 FBXO11 HUWE1 CREBBP KAT7 UBE2O RNF103 FBXO21 EP300 CDC23

9.87e-0477510812GO:0016746
GeneOntologyMolecularFunctionhistone modifying activity

HUWE1 KMT2E CREBBP KAT7 KDM2B EP300

1.54e-032291086GO:0140993
GeneOntologyMolecularFunctionpeptidyl-proline dioxygenase activity

P3H2 P3H1

1.85e-03121082GO:0031543
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

CUL4A FBXO40 RGPD1 FBXO11 HUWE1 UBE2O RNF103 FBXO21 CDC23

1.85e-035121089GO:0019787
GeneOntologyMolecularFunctioncarboxylic acid binding

GRIN1 GRIN2B TYMS IGF2R P3H2 P3H1

1.91e-032391086GO:0031406
GeneOntologyMolecularFunctiondioxygenase activity

TET2 P3H2 P3H1 KDM2B

1.98e-03981084GO:0051213
GeneOntologyBiologicalProcesscellular component maintenance

GRIN1 GRIN2B NRXN1 PRICKLE2 BSN CTTN

1.44e-051011076GO:0043954
GeneOntologyBiologicalProcessmonocyte activation involved in immune response

DYSF FER1L5

2.67e-0521072GO:0002280
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

GRIN1 GRIN2B CPLX4 DYSF PPP3CB NRXN1 NRXN2 CPLX3 NISCH BSN FER1L5 BEGAIN EPHA7

3.93e-0566310713GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

GRIN1 GRIN2B CPLX4 DYSF PPP3CB NRXN1 NRXN2 CPLX3 NISCH BSN FER1L5 BEGAIN EPHA7

3.99e-0566410713GO:0099177
GeneOntologyBiologicalProcessregulation of postsynapse organization

GRIN1 GRIN2B NRXN1 NRXN2 CAPRIN2 PRICKLE2 EPHA7

5.11e-051851077GO:0099175
GeneOntologyBiologicalProcessregulation of organelle organization

TPR NUMA1 ATL3 SSBP1 HUWE1 NEB DYSF FCHSD2 TFPT DLC1 PPP3CB NRXN1 CPLX3 PRICKLE2 SMARCA2 CTTN PREX1 EP300 CDC23

5.59e-05134210719GO:0033043
GeneOntologyBiologicalProcesscognition

CHL1 AFF2 GRIN1 GRIN2B CREBBP PPP3CB NRXN1 NRXN2 ANKRD11 EP300

7.08e-0542310710GO:0050890
GeneOntologyBiologicalProcesschromatin remodeling

TET2 TPR HUWE1 KMT2E IFI16 CREBBP KAT7 TFPT BRDT EPC1 SMARCA2 KDM2B EP300

1.21e-0474110713GO:0006338
GeneOntologyBiologicalProcessneuroligin clustering involved in postsynaptic membrane assembly

NRXN1 NRXN2

1.59e-0441072GO:0097118
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

1.59e-0441072GO:0018076
GeneOntologyBiologicalProcessregulation of DNA repair

CUL4A CREBBP KAT7 TFPT EPC1 SMARCA2 PNP

2.20e-042341077GO:0006282
GeneOntologyBiologicalProcesspostsynapse organization

GRIN1 GRIN2B NRXN1 NRXN2 CAPRIN2 PRICKLE2 CTTN EPHA7

2.28e-043131078GO:0099173
GeneOntologyBiologicalProcessgephyrin clustering involved in postsynaptic density assembly

NRXN1 NRXN2

2.64e-0451072GO:0097116
GeneOntologyBiologicalProcesspresynaptic active zone assembly

NRXN1 BSN

2.64e-0451072GO:1904071
GeneOntologyBiologicalProcesspositive regulation of protein localization to nucleus

TPR CREBBP KAT7 PPP3CB EP300

3.21e-041141075GO:1900182
GeneOntologyBiologicalProcessneuron projection development

CHL1 PRTG GRIN1 ITGA1 CREBBP PTPN9 ARSB PPP3CB NRXN1 PTPRM P3H1 CAPRIN2 PRICKLE2 CTTN PREX1 EP300 EPHA7

3.23e-04128510717GO:0031175
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

GRIN1 GRIN2B CPLX4 DYSF FCHSD2 PPP3CB NRXN1 NRXN2 CPLX3 NISCH BSN FER1L5 BEGAIN EPHA7

3.23e-0493110714GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

GRIN1 GRIN2B CPLX4 DYSF FCHSD2 PPP3CB NRXN1 NRXN2 CPLX3 NISCH BSN FER1L5 BEGAIN EPHA7

3.23e-0493110714GO:0007268
GeneOntologyBiologicalProcesspositive regulation of DNA metabolic process

SSBP1 CREBBP KAT7 TFPT EPC1 CST3 SMARCA2 PNP

3.46e-043331078GO:0051054
GeneOntologyBiologicalProcesstrans-synaptic signaling

GRIN1 GRIN2B CPLX4 DYSF FCHSD2 PPP3CB NRXN1 NRXN2 CPLX3 NISCH BSN FER1L5 BEGAIN EPHA7

3.52e-0493910714GO:0099537
GeneOntologyBiologicalProcesspeptidyl-lysine acetylation

CREBBP KAT7 EP300

4.05e-04281073GO:0018394
GeneOntologyBiologicalProcessprotein acetylation

CREBBP KAT7 ANKRD11 EP300

4.32e-04681074GO:0006473
GeneOntologyBiologicalProcessDNA damage response

CUL4A NUGGC IRF3 RECQL HUWE1 IFI16 CREBBP KAT7 TFPT EPC1 SMARCA2 MTREX EP300 PNP

4.35e-0495910714GO:0006974
GeneOntologyBiologicalProcessregulation of nucleotide-excision repair

CUL4A KAT7 SMARCA2

4.50e-04291073GO:2000819
GeneOntologyBiologicalProcessdendritic spine maintenance

GRIN1 GRIN2B CTTN

4.98e-04301073GO:0097062
GeneOntologyBiologicalProcessneuron development

CHL1 PRTG CDHR1 GRIN1 ITGA1 CREBBP PTPN9 ARSB PPP3CB NRXN1 PTPRM P3H1 CAPRIN2 PRICKLE2 CTTN PREX1 EP300 EPHA7

5.06e-04146310718GO:0048666
GeneOntologyBiologicalProcesssynaptic signaling

GRIN1 GRIN2B CPLX4 DYSF FCHSD2 PPP3CB NRXN1 NRXN2 CPLX3 NISCH BSN FER1L5 BEGAIN EPHA7

5.18e-0497610714GO:0099536
GeneOntologyBiologicalProcesssignal release from synapse

CPLX4 DYSF NRXN1 NRXN2 CPLX3 FER1L5

5.42e-041951076GO:0099643
GeneOntologyBiologicalProcessneurotransmitter secretion

CPLX4 DYSF NRXN1 NRXN2 CPLX3 FER1L5

5.42e-041951076GO:0007269
GeneOntologyBiologicalProcessvocal learning

NRXN1 NRXN2

5.50e-0471072GO:0042297
GeneOntologyBiologicalProcessimitative learning

NRXN1 NRXN2

5.50e-0471072GO:0098596
GeneOntologyCellularComponentpresynaptic active zone membrane

GRIN1 GRIN2B NRXN1 NRXN2 CPLX3

5.25e-05781085GO:0048787
GeneOntologyCellularComponentmitotic spindle midzone

TTC28 NUMA1 CTTN

7.15e-05161083GO:1990023
GeneOntologyCellularComponentpresynaptic active zone

GRIN1 GRIN2B NRXN1 NRXN2 CPLX3 BSN

9.21e-051411086GO:0048786
GeneOntologyCellularComponentnuclear inclusion body

TPR RGPD1 IFI16

1.43e-04201083GO:0042405
GeneOntologyCellularComponentexocytic vesicle membrane

GRIN1 DYSF RAB3C CPLX3 BSN FER1L5

3.37e-041791086GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

GRIN1 DYSF RAB3C CPLX3 BSN FER1L5

3.37e-041791086GO:0030672
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

GRIN1 GRIN2B BSN EPHA7

4.02e-04671084GO:0098686
GeneOntologyCellularComponentdendritic branch

GRIN1 GRIN2B

5.46e-0471082GO:0044307
GeneOntologyCellularComponenttransport vesicle membrane

GRIN1 GRIN2B DYSF RAB3C CPLX3 BSN FER1L5

8.26e-042931087GO:0030658
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex, eIF3m

EIF3CL EIF3D

9.30e-0491082GO:0071541
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN1 GRIN2B

9.30e-0491082GO:0017146
GeneOntologyCellularComponentsynaptic vesicle

GRIN1 GRIN2B DYSF RAB3C CPLX3 BSN FER1L5

9.48e-043001087GO:0008021
GeneOntologyCellularComponentspindle midzone

TTC28 NUMA1 CTTN

1.15e-03401083GO:0051233
GeneOntologyCellularComponentneuron projection terminus

GRIN1 GRIN2B CPLX4 PTPN9 CPLX3 BSN

1.34e-032331086GO:0044306
GeneOntologyCellularComponentexocytic vesicle

GRIN1 GRIN2B DYSF RAB3C CPLX3 BSN FER1L5

1.37e-033201087GO:0070382
GeneOntologyCellularComponenthistone acetyltransferase complex

CREBBP KAT7 EPC1 EP300

1.44e-03941084GO:0000123
GeneOntologyCellularComponentterminal bouton

GRIN1 GRIN2B CPLX4 CPLX3

1.55e-03961084GO:0043195
GeneOntologyCellularComponentendoplasmic reticulum lumen

CP ACE2 ARSB P3H2 P3H1 CST3 OS9

1.70e-033321087GO:0005788
GeneOntologyCellularComponentnuclear speck

NUGGC SRSF4 AFF2 KMT2E IFI16 PRPF18 RBM8A MTREX

1.79e-034311088GO:0016607
GeneOntologyCellularComponentprotein acetyltransferase complex

CREBBP KAT7 EPC1 EP300

2.08e-031041084GO:0031248
GeneOntologyCellularComponentexcitatory synapse

GRIN1 GRIN2B NRXN1 BSN

2.31e-031071084GO:0060076
GeneOntologyCellularComponentacetyltransferase complex

CREBBP KAT7 EPC1 EP300

2.47e-031091084GO:1902493
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex

EIF3CL EIF3D

3.03e-03161082GO:0005852
HumanPhenoHumoral immunodeficiency

CREBBP EP300 PNP

6.44e-073453HP:0005363
HumanPhenoSyringomyelia

FBXO11 ACY1 CREBBP RBM8A EP300

8.46e-0633455HP:0003396
HumanPhenoSpinal cord lesion

FBXO11 ACY1 CREBBP RBM8A EP300

4.48e-0546455HP:0100561
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

7.63e-052452HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

7.63e-052452HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

7.63e-052452HP:0001042
HumanPhenoBroad distal phalanx of finger

FBXO11 CREBBP SMARCA2 EP300

8.04e-0527454HP:0009836
HumanPhenoFacial grimacing

CP CREBBP EP300

1.73e-0413453HP:0000273
HumanPhenoKeloids

CREBBP AEBP1 EP300

1.73e-0413453HP:0010562
HumanPhenoSmooth philtrum

TPR RECQL FBXO11 CREBBP DHPS SMARCA2 ANKRD11 EP300

1.77e-04185458HP:0000319
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

2.28e-043452HP:0008752
HumanPhenoPhobia

CREBBP EP300

2.28e-043452HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

2.28e-043452HP:0000756
HumanPhenoProminent nasal septum

CREBBP EP300

2.28e-043452HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

2.28e-043452HP:0005895
HumanPhenoPoor coordination

AFF2 HUWE1 CREBBP EP300

3.49e-0439454HP:0002370
HumanPhenoDeeply set eye

TPR RECQL FBXO11 GRIN1 HUWE1 KMT2E CREBBP DHPS EP300

4.25e-04266459HP:0000490
HumanPhenoTrichiasis

CREBBP EP300

4.53e-044452HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

4.53e-044452HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

4.53e-044452HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

4.53e-044452HP:0006200
HumanPhenoVascular ring

CREBBP EP300

4.53e-044452HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

4.53e-044452HP:0031207
HumanPhenoLow posterior hairline

HUWE1 CREBBP AEBP1 SMARCA2 ANKRD11 EP300

5.06e-04117456HP:0002162
HumanPhenoAbnormality of the posterior hairline

HUWE1 CREBBP AEBP1 SMARCA2 ANKRD11 EP300

5.06e-04117456HP:0030141
DomainTPR_REGION

TTC28 RGPD1 P3H2 P3H1 TTC21B CFAP70 CLUH CDC23

5.21e-061651088PS50293
DomainTPR

TTC28 RGPD1 P3H2 P3H1 TTC21B CFAP70 CLUH CDC23

5.21e-061651088PS50005
DomainBromodomain_CS

CREBBP BRDT SMARCA2 EP300

1.43e-05261084IPR018359
Domain-

TTC28 RGPD1 P3H2 P3H1 TTC21B CFAP70 CLUH CDC23

2.71e-0520710881.25.40.10
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

3.31e-0521082IPR014744
DomainZnF_TAZ

CREBBP EP300

3.31e-0521082SM00551
Domain-

CREBBP EP300

3.31e-05210821.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

3.31e-0521082IPR010303
Domain-

CREBBP EP300

3.31e-05210821.10.1630.10
DomainCreb_binding

CREBBP EP300

3.31e-0521082PF09030
Domainzf-TAZ

CREBBP EP300

3.31e-0521082PF02135
DomainZF_TAZ

CREBBP EP300

3.31e-0521082PS50134
DomainKAT11

CREBBP EP300

3.31e-0521082SM01250
DomainZnf_TAZ

CREBBP EP300

3.31e-0521082IPR000197
DomainKIX

CREBBP EP300

3.31e-0521082PF02172
DomainHAT_KAT11

CREBBP EP300

3.31e-0521082PF08214
DomainKIX

CREBBP EP300

3.31e-0521082PS50952
DomainCBP_P300_HAT

CREBBP EP300

3.31e-0521082IPR031162
DomainDUF902

CREBBP EP300

3.31e-0521082PF06001
Domain-

CREBBP EP300

3.31e-05210821.10.246.20
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

3.31e-0521082IPR013178
DomainKIX_dom

CREBBP EP300

3.31e-0521082IPR003101
DomainCBP_P300_HAT

CREBBP EP300

3.31e-0521082PS51727
DomainBROMODOMAIN_1

CREBBP BRDT SMARCA2 EP300

6.03e-05371084PS00633
DomainTPR-like_helical_dom

TTC28 RGPD1 P3H2 P3H1 TTC21B CFAP70 CLUH CDC23

6.27e-052331088IPR011990
DomainBromodomain

CREBBP BRDT SMARCA2 EP300

6.71e-05381084PF00439
DomainBROMODOMAIN_2

CREBBP BRDT SMARCA2 EP300

9.08e-05411084PS50014
DomainFerA

DYSF FER1L5

9.90e-0531082SM01200
DomainFerlin_A-domain

DYSF FER1L5

9.90e-0531082IPR012560
DomainFerA

DYSF FER1L5

9.90e-0531082PF08165
DomainBromodomain

CREBBP BRDT SMARCA2 EP300

9.99e-05421084IPR001487
DomainBROMO

CREBBP BRDT SMARCA2 EP300

9.99e-05421084SM00297
Domain-

CREBBP BRDT SMARCA2 EP300

9.99e-054210841.20.920.10
DomainSynaphin

CPLX4 CPLX3

1.97e-0441082PF05835
DomainDysFC

DYSF FER1L5

1.97e-0441082SM00694
DomainDysFN

DYSF FER1L5

1.97e-0441082SM00693
DomainSynaphin

CPLX4 CPLX3

1.97e-0441082IPR008849
DomainPeroxin/Ferlin

DYSF FER1L5

1.97e-0441082IPR006614
DomainTPR-contain_dom

TTC28 RGPD1 P3H1 TTC21B CFAP70 CDC23

2.37e-041501086IPR013026
DomainTPR_8

TTC28 TTC21B CFAP70 CDC23

2.49e-04531084PF13181
DomainFerI

DYSF FER1L5

3.28e-0451082SM01202
DomainFerB

DYSF FER1L5

3.28e-0451082SM01201
DomainFerlin_B-domain

DYSF FER1L5

3.28e-0451082IPR012561
DomainFerlin_C

DYSF FER1L5

3.28e-0451082PF16165
DomainFerlin_C

DYSF FER1L5

3.28e-0451082IPR032362
DomainFerIin_dom

DYSF FER1L5

3.28e-0451082IPR012968
DomainFerI

DYSF FER1L5

3.28e-0451082PF08151
DomainFerB

DYSF FER1L5

3.28e-0451082PF08150
DomainNuc_rcpt_coact

CREBBP EP300

4.89e-0461082IPR009110
Domain-

IGF2R OS9

4.89e-04610822.70.130.10
DomainF-box

FBXO40 FBXO11 KDM2B FBXO21

6.12e-04671084PF00646
DomainSyndecan

NRXN1 NRXN2

6.83e-0471082PF01034
DomainSyndecan/Neurexin_dom

NRXN1 NRXN2

6.83e-0471082IPR027789
DomainFBOX

FBXO40 FBXO11 KDM2B FBXO21

8.04e-04721084PS50181
DomainPectin_lyase_fold/virulence

FBXO11 CEMIP2

9.07e-0481082IPR011050
DomainMan6P_isomerase_rcpt-bd_dom

IGF2R OS9

9.07e-0481082IPR009011
DomainTPR

TTC28 RGPD1 TTC21B CFAP70 CDC23

9.18e-041291085SM00028
DomainF-box_dom

FBXO40 FBXO11 KDM2B FBXO21

9.37e-04751084IPR001810
DomainTPR_repeat

TTC28 RGPD1 TTC21B CFAP70 CDC23

1.05e-031331085IPR019734
DomainPTPc

PTPN3 PTPN9 PTPRM

1.17e-03361083SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN3 PTPN9 PTPRM

1.48e-03391083PS50055
DomainPTPase_domain

PTPN3 PTPN9 PTPRM

1.71e-03411083IPR000242
DomainY_phosphatase

PTPN3 PTPN9 PTPRM

1.71e-03411083PF00102
Domain2OG-FeII_Oxy_3

P3H2 P3H1

1.76e-03111082PF13640
Domainfn3

CHL1 PRTG IGDCC4 PTPRM EPHA7

2.51e-031621085PF00041
DomainWHTH_DNA-bd_dom

CUL4A IRF3 RECQL EIF3CL KAT7 PREX1

2.83e-032421086IPR011991
DomainNeurexin-like

NRXN1 NRXN2

2.88e-03141082IPR003585
Domain4.1m

NRXN1 NRXN2

2.88e-03141082SM00294
DomainHelicase_C

DDX60 RECQL SMARCA2 MTREX

3.46e-031071084PF00271
DomainHELICc

DDX60 RECQL SMARCA2 MTREX

3.46e-031071084SM00490
DomainHelicase_C

DDX60 RECQL SMARCA2 MTREX

3.57e-031081084IPR001650
DomainHELICASE_CTER

DDX60 RECQL SMARCA2 MTREX

3.69e-031091084PS51194
DomainHELICASE_ATP_BIND_1

DDX60 RECQL SMARCA2 MTREX

3.69e-031091084PS51192
DomainDEXDc

DDX60 RECQL SMARCA2 MTREX

3.69e-031091084SM00487
DomainP4Hc

P3H2 P3H1

3.77e-03161082SM00702
DomainPro_4_hyd_alph

P3H2 P3H1

3.77e-03161082IPR006620
DomainHelicase_ATP-bd

DDX60 RECQL SMARCA2 MTREX

3.82e-031101084IPR014001
DomainFN3

CHL1 PRTG IGDCC4 PTPRM EPHA7

4.43e-031851085SM00060
DomainLig_chan-Glu_bd

GRIN1 GRIN2B

4.77e-03181082PF10613
DomainGlu/Gly-bd

GRIN1 GRIN2B

4.77e-03181082IPR019594
DomainLig_chan-Glu_bd

GRIN1 GRIN2B

4.77e-03181082SM00918
DomainZF_ZZ_2

CREBBP EP300

4.77e-03181082PS50135
DomainZF_ZZ_1

CREBBP EP300

4.77e-03181082PS01357
DomainIontro_rcpt

GRIN1 GRIN2B

4.77e-03181082IPR001320
DomainIono_rcpt_met

GRIN1 GRIN2B

4.77e-03181082IPR001508
DomainZZ

CREBBP EP300

4.77e-03181082PF00569
DomainLig_chan

GRIN1 GRIN2B

4.77e-03181082PF00060
DomainPBPe

GRIN1 GRIN2B

4.77e-03181082SM00079
DomainPTPc_motif

PTPN3 PTPN9 PTPRM

4.83e-03591083SM00404
DomainTyr_Pase_cat

PTPN3 PTPN9 PTPRM

4.83e-03591083IPR003595
DomainZnf_ZZ

CREBBP EP300

5.31e-03191082IPR000433
DomainZnF_ZZ

CREBBP EP300

5.31e-03191082SM00291
Domain2OG-FeII_Oxy

P3H2 P3H1

5.31e-03191082PF03171
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

IRF3 CREBBP EP300

2.17e-065863M27228
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

IRF3 CREBBP EP300

1.79e-059863M47451
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

GRIN1 GRIN2B NRXN1 NRXN2 BEGAIN

2.25e-0556865M27616
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

GRIN1 GRIN2B NRXN1 NRXN2

4.62e-0533864M39875
PathwayKEGG_LONG_TERM_POTENTIATION

GRIN1 GRIN2B CREBBP PPP3CB EP300

6.66e-0570865M3115
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

IRF3 CREBBP EP300

9.46e-0515863M953
PathwayWP_NRXN1_DELETION_SYNDROME

GRIN1 GRIN2B NRXN1

1.67e-0418863M48098
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

GRIN1 GRIN2B NRXN1 NRXN2 BEGAIN

1.87e-0487865M27617
PathwayBIOCARTA_NOS1_PATHWAY

GRIN1 GRIN2B PPP3CB

2.32e-0420863MM1445
PathwayBIOCARTA_NOS1_PATHWAY

GRIN1 GRIN2B PPP3CB

2.69e-0421863M11650
PathwayPID_AR_TF_PATHWAY

CREBBP KAT7 SMARCA2 EP300

3.01e-0453864M151
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

3.64e-045862MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

3.64e-045862M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

3.64e-045862M48023
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN1 GRIN2B

3.64e-045862M47667
PathwayPID_P53_REGULATION_PATHWAY

FBXO11 HUWE1 CREBBP EP300

4.55e-0459864M261
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

5.43e-046862M22062
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN1 GRIN2B

5.43e-046862M47668
PathwayREACTOME_CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA

IRF3 IFI16 CREBBP EP300

6.21e-0464864M27046
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

7.57e-047862MM1573
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

IRF3 CREBBP EP300

7.90e-0430863M936
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

CREBBP PPP3CB EP300

9.57e-0432863M39521
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.01e-038862M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

1.01e-038862M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

1.01e-038862M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

1.01e-038862M46443
PathwayPID_E2F_PATHWAY

CREBBP TYMS SMARCA2 EP300

1.02e-0373864M40
PathwayREACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES

IRF3 CREBBP EP300

1.25e-0335863M48246
PathwayBIOCARTA_PCAF_PATHWAY

IRF3 CREBBP

1.29e-039862MM1533
PathwayREACTOME_CHL1_INTERACTIONS

CHL1 ITGA1

1.29e-039862M27379
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TPR NUMA1 RGPD1 GRIN1 GRIN2B HUWE1 RAB3C PTPN9 UBE2O IGF2R PPP3CB NRXN1 ZC3H4 NISCH BSN CTTN BEGAIN

9.94e-099631101728671696
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

SRSF4 ATL3 HUWE1 CKB TYMS PTPN3 PTPN9 UBE2O GET4 PTPRM DHPS OS9 AKAP10 CTTN FBXO21 CLUH XPR1

1.17e-089741101728675297
Pubmed

Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.

GRIN1 GRIN2B CREBBP CTTN EP300

2.68e-0828110531600191
Pubmed

Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

IRF3 CREBBP EP300

3.08e-08311039488451
Pubmed

Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein-protein interactions.

IRF3 CREBBP EP300

3.08e-083110312473110
Pubmed

Kaposi's sarcoma-associated herpesvirus-encoded vIRF-3 stimulates the transcriptional activity of cellular IRF-3 and IRF-7.

IRF3 CREBBP EP300

3.08e-083110314668346
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

TPR NUMA1 HUWE1 IFI16 EIF3CL KAT7 ZC3H4 EPC1 RBM8A CTTN CDC23 BEGAIN

7.17e-085031101216964243
Pubmed

HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators.

IRF3 CREBBP EP300

1.23e-074110311314014
Pubmed

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo.

IRF3 CREBBP EP300

1.23e-07411039660935
Pubmed

Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivators.

IRF3 CREBBP EP300

1.23e-074110312604599
Pubmed

Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex.

IRF3 CREBBP EP300

1.23e-074110311940575
Pubmed

Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.

IRF3 CREBBP EP300

1.23e-074110317126870
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TTC28 RGPD1 SSBP1 NEB CREBBP PTPN9 SMARCA2 KDM2B RBM8A BSN FER1L5 PREX1 EP300

1.23e-076381101331182584
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TPR SRSF4 NUMA1 RECQL HUWE1 CKB UBE2O IGF2R SMARCA2 EIF3D MTREX CLUH PNP

1.60e-076531101322586326
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CUL4A TTC28 ACY1 CREBBP ZKSCAN5 KAT7 TFPT ARSB BRDT ZC3H4 EPC1 CAPRIN2 DHPS SMARCA2 EP300 CDC23

4.69e-0711161101631753913
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

CUL4A FLG TTC28 RBM45 FBXO11 HUWE1 CKB TFPT UBE2O GET4 IGF2R P3H1 SMARCA2 RBM8A EIF3D

6.72e-0710051101519615732
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

CREBBP KAT7 EPC1 SMARCA2 ANKRD11 KDM2B EP300

7.20e-07157110730186101
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

CP ITGA1 HUWE1 ACY1 NEB DYSF CEMIP2 CKB ACE2 IGF2R P3H1 CST3 RAB15 CFAP70 PNP

7.69e-0710161101519056867
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TET2 LAPTM4A RNMT CEMIP2 UBE2O NRXN2 ZC3H4 CAPRIN2 KDM2B MTREX BSN

9.99e-075291101114621295
Pubmed

New nomenclature for chromatin-modifying enzymes.

KMT2E CREBBP KAT7 KDM2B EP300

1.06e-0657110518022353
Pubmed

A switch from hBrm to Brg1 at IFNγ-activated sequences mediates the activation of human genes.

CREBBP SMARCA2 EP300

1.07e-067110321079652
Pubmed

Structurally and functionally unique complexins at retinal ribbon synapses.

CPLX4 CPLX3 BSN

1.07e-067110315911881
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

RNMT RECQL FBXO11 CREBBP TYMS PTPN9 UBE2O OS9 EP300 YTHDF3 CDC23

1.07e-065331101125544563
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TPR NUMA1 HUWE1 IFI16 EIF3CL PAXBP1 ZC3H4 SMARCA2 KDM2B RBM8A CTTN CLUH CDC23

1.09e-067741101315302935
Pubmed

Interaction network of human early embryonic transcription factors.

TET2 RGPD1 SSBP1 CREBBP EPC1 SMARCA2 KDM2B EP300 YTHDF3

1.86e-06351110938297188
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

CUL4A TPR SRSF4 NUMA1 RECQL FBXO11 HUWE1 PAXBP1 DHPS SMARCA2 KDM2B RBM8A EIF3D MTREX CTTN YTHDF3

1.99e-0612471101627684187
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TET2 RNMT CREBBP PAXBP1 ZC3H4 EPC1 SMARCA2 KDM2B

2.33e-06268110833640491
Pubmed

Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.

NRXN1 NRXN2 BSN

2.55e-069110321356198
Pubmed

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.

NRXN1 NRXN2 EPHA7

2.55e-06911039707552
Pubmed

Human transcription factor protein interaction networks.

TET2 FLG NUMA1 RGPD1 IRF3 SSBP1 CREBBP CKB TFPT UBE2O EPC1 SMARCA2 KDM2B EIF3D CTTN EP300 YTHDF3

2.56e-0614291101735140242
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

TPR CCPG1 SRSF4 NUMA1 SSBP1 IFI16 KAT7 PAXBP1 ZC3H4 RBM8A MTREX YTHDF3 PNP

2.92e-068471101335850772
Pubmed

Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

TPR NUMA1 UBE2O CTTN

3.18e-0632110427437069
Pubmed

Immune evasion strategy involving propionylation by the KSHV interferon regulatory factor 1 (vIRF1).

IRF3 CREBBP EP300

3.63e-0610110337023208
Pubmed

The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.

CUL4A CREBBP EP300

3.63e-0610110320347598
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

TET2 TTC28 NRXN1 NRXN2 FBXO21 CLUH

3.78e-06130110612421765
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CUL4A TPR RNMT NUMA1 RECQL IFI16 CREBBP KAT7 SMARCA2 RBM8A MTREX CTTN EP300 CDC23

4.01e-0610141101432416067
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

CUL4A HUWE1 EIF3CL CKB NISCH RAB15 RBM8A EIF3D CTTN FBXO21

4.10e-064951101028581483
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CHL1 AFF2 DDX60 SSBP1 CKB CAPRIN2 BSN

4.67e-06208110733230847
Pubmed

A cohesin-RAD21 interactome.

CUL4A TPR CP UBE2O EIF3D MTREX CTTN

4.67e-06208110722145905
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

CUL4A TPR FBXO11 HUWE1 KAT7 BRDT P3H1 KDM2B EIF3D

4.96e-06396110926687479
Pubmed

CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins.

GRIN1 GRIN2B NRXN2

4.99e-061111039647694
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

TPR SRSF4 NUMA1 RECQL SSBP1 KAT7 P3H1 RBM8A EIF3D MTREX CTTN

8.25e-066601101132780723
Pubmed

A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.

TET2 PRICKLE2 EPHA7

8.60e-0613110326989192
Pubmed

The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.

TPR TTC28 RECQL HUWE1 CEMIP2 TYMS NISCH EIF3D

9.57e-06325110836168628
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

RGPD1 HUWE1 EIF3CL KAT7 EIF3D CDC23

9.65e-06153110626365490
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

CUL4A TPR NUMA1 RECQL SSBP1 HUWE1 CKB UBE2O PAXBP1 ZC3H4 RBM8A EIF3D MTREX CTTN CLUH YTHDF3

9.84e-0614151101628515276
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

9.91e-062110227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

9.91e-062110234845315
Pubmed

Glutamatergic signaling maintains the epithelial phenotype of proximal tubular cells.

GRIN1 GRIN2B

9.91e-062110221597037
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

9.91e-062110219729597
Pubmed

Crystal structure of IRF-3 in complex with CBP.

IRF3 CREBBP

9.91e-062110216154084
Pubmed

Genetic variants of the NMDA receptor influence cortical excitability and plasticity in humans.

GRIN1 GRIN2B

9.91e-062110221753020
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

9.91e-062110239287984
Pubmed

Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV.

P3H2 P3H1

9.91e-062110218487197
Pubmed

Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.

NRXN1 NRXN2

9.91e-062110230709877
Pubmed

Pathogenic variants in EP300 and ANKRD11 in patients with phenotypes overlapping Cornelia de Lange syndrome.

ANKRD11 EP300

9.91e-062110232476269
Pubmed

Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association.

IRF3 CREBBP

9.91e-062110218272581
Pubmed

An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray.

GRIN1 GRIN2B

9.91e-062110215841096
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

9.91e-062110220717166
Pubmed

An endoplasmic reticulum retention signal located in the extracellular amino-terminal domain of the NR2A subunit of N-Methyl-D-aspartate receptors.

GRIN1 GRIN2B

9.91e-062110219487695
Pubmed

Light-dependent regulation of neurotransmitter release from rod photoreceptor ribbon synapses involves an interplay of Complexin 4 and Transducin with the SNARE complex.

CPLX4 CPLX3

9.91e-062110238481472
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

9.91e-062110225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

9.91e-062110211559821
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

9.91e-062110232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

9.91e-062110219822209
Pubmed

Functional Roles of Complexin 3 and Complexin 4 at Mouse Photoreceptor Ribbon Synapses.

CPLX4 CPLX3

9.91e-062110227335398
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

9.91e-062110224522976
Pubmed

Excitotoxic superoxide production and neuronal death require both ionotropic and non-ionotropic NMDA receptor signaling.

GRIN1 GRIN2B

9.91e-062110230504838
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

9.91e-062110221847097
Pubmed

Influence of Genetic Variants of the N-Methyl-D-Aspartate Receptor on Emotion and Social Behavior in Adolescents.

GRIN1 GRIN2B

9.91e-062110226819771
Pubmed

GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome.

GRIN1 GRIN2B

9.91e-062110226041915
Pubmed

Computationally Discovered Potentiating Role of Glycans on NMDA Receptors.

GRIN1 GRIN2B

9.91e-062110228378791
Pubmed

Redox regulation of neuronal migration in a Down Syndrome model.

GRIN1 GRIN2B

9.91e-062110212957649
Pubmed

Key amino acid residues within the third membrane domains of NR1 and NR2 subunits contribute to the regulation of the surface delivery of N-methyl-D-aspartate receptors.

GRIN1 GRIN2B

9.91e-062110222711533
Pubmed

Region-specific role for GluN2B-containing NMDA receptors in injury to Purkinje cells and CA1 neurons following global cerebral ischemia.

GRIN1 GRIN2B

9.91e-062110225450957
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

9.91e-062110234813504
Pubmed

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein.

IRF3 IFI16

9.91e-062110223027953
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

9.91e-062110220301699
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

9.91e-062110224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

9.91e-062110237816914
Pubmed

Polymorphisms in the N-methyl-D-aspartate receptor 1 and 2B subunits are associated with alcoholism-related traits.

GRIN1 GRIN2B

9.91e-062110214573320
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

9.91e-062110211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

9.91e-062110210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

9.91e-062110235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

9.91e-062110231898871
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

9.91e-062110230888860
Pubmed

Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors composed of an NR1/NR2B subunit assembly.

GRIN1 GRIN2B

9.91e-062110219224577
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

9.91e-062110227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

9.91e-062110219272189
Pubmed

Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1.

IRF3 CREBBP

9.91e-062110226773386
Pubmed

A Rare Variant Identified Within the GluN2B C-Terminus in a Patient with Autism Affects NMDA Receptor Surface Expression and Spine Density.

GRIN1 GRIN2B

9.91e-062110228283559
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

9.91e-062110232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

9.91e-062110230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

9.91e-062110221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

9.91e-06211029811832
Pubmed

Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.

NRXN1 NRXN2

9.91e-062110226595880
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

9.91e-062110224089570
Pubmed

Effects of cocaine-kindling on the expression of NMDA receptors and glutamate levels in mouse brain.

GRIN1 GRIN2B

9.91e-062110220927585
Pubmed

Activation of interferon regulatory factor 3 in response to DNA-damaging agents.

IRF3 CREBBP

9.91e-062110210521456
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

9.91e-062110215706485
InteractionEIF3L interactions

CUL4A DDX60 NUMA1 HUWE1 HTRA4 IFI16 EIF3CL ACE2 TTC21B RBM8A EIF3D EP300

8.41e-0924410912int:EIF3L
InteractionAPPL1 interactions

CUL4A RNMT GRIN1 HUWE1 DYSF EIF3CL ACE2 UBE2O CLUH EPHA7

5.55e-0818210910int:APPL1
InteractionEIF5A interactions

TPR RBM45 NUMA1 HUWE1 TYMS ACE2 PTPN3 UBE2O NRXN1 DHPS CTTN

3.91e-0728310911int:EIF5A
InteractionBMI1 interactions

CUL4A SRSF4 NUMA1 RECQL IFI16 CREBBP EIF3CL TFPT PAXBP1 ZC3H4 SMARCA2 KDM2B EIF3D MTREX EP300 YTHDF3

5.05e-0765910916int:BMI1
InteractionEIF3I interactions

CUL4A DDX60 NUMA1 HUWE1 EIF3CL ACE2 RBM8A EIF3D CLUH EP300

1.39e-0625810910int:EIF3I
InteractionAR interactions

TET2 TPR RNMT NUMA1 RECQL HUWE1 ACY1 IFI16 CREBBP CKB KAT7 PAXBP1 ZC3H4 NISCH EPC1 SMARCA2 KDM2B MTREX EP300

1.42e-0699210919int:AR
InteractionVCP interactions

ANKRD13B CUL4A RNMT NUMA1 ATL3 CP ITGA1 HUWE1 NEB EIF3CL ACE2 PTPN3 FCHSD2 PTPN9 GET4 NRXN1 RNF103 PTPRM OS9 RBM8A EP300 PNP

7.29e-06143510922int:VCP
InteractionCSNK2A2 interactions

CUL4A SSBP1 GRIN2B HUWE1 IFI16 CREBBP EIF3CL TFPT UBE2O PPP3CB BRDT ZC3H4 KDM2B EIF3D EP300

7.41e-0671810915int:CSNK2A2
InteractionKLF5 interactions

TET2 FLG CREBBP EPC1 SMARCA2 KDM2B EP300 YTHDF3

1.10e-051951098int:KLF5
InteractionUBE2M interactions

CUL4A HUWE1 EIF3CL CKB TYMS ACE2 IGF2R NISCH RAB15 RBM8A EIF3D CTTN FBXO21 EP300

1.11e-0565110914int:UBE2M
InteractionCIITA interactions

FBXO11 IFI16 CREBBP SMARCA2 EP300

1.18e-05551095int:CIITA
InteractionPWP1 interactions

CUL4A SSBP1 HUWE1 IFI16 UBE2O RBM8A EIF3D EP300

1.23e-051981098int:PWP1
InteractionSOX9 interactions

CUL4A RGPD1 CREBBP SMARCA2 KDM2B EP300

1.44e-05971096int:SOX9
InteractionBANF1 interactions

CUL4A NUMA1 RECQL HUWE1 ACE2 BRDT SMARCA2 EPHA7

1.52e-052041098int:BANF1
InteractionUSP7 interactions

CUL4A TET2 TPR SRSF4 RBM45 DDX60 NUMA1 HUWE1 NEB KMT2E IFI16 CREBBP ACE2 BTN2A2 UBE2O DLC1 MTREX BSN CTTN EP300

2.24e-05131310920int:USP7
InteractionEIF3H interactions

CUL4A DDX60 NUMA1 EIF3CL RBM8A EIF3D MTREX CTTN EP300

2.28e-052821099int:EIF3H
InteractionNUP98 interactions

TPR NUMA1 RGPD1 HUWE1 IFI16 CREBBP ACE2 EP300

2.62e-052201098int:NUP98
InteractionPAX8 interactions

TET2 CREBBP CKB SMARCA2 KDM2B EP300

3.11e-051111096int:PAX8
InteractionLZTR1 interactions

CUL4A IFI16 CKB PTPN9 UBE2O KDM2B

3.11e-051111096int:LZTR1
InteractionTP53BP1 interactions

RNMT NUMA1 RECQL GRIN1 HUWE1 IFI16 CREBBP TYMS PTPN9 ZC3H4 EP300 CDC23

3.16e-0553310912int:TP53BP1
InteractionCSNK2B interactions

GRIN2B IFI16 CREBBP KAT7 ACE2 TFPT UBE2O BRDT ZC3H4 ANKRD11 EIF3D MTREX EP300

3.31e-0562510913int:CSNK2B
InteractionGCM1 interactions

TET2 CREBBP SMARCA2 KDM2B EP300

3.35e-05681095int:GCM1
InteractionBSN interactions

GRIN1 NRXN1 BSN EP300

3.73e-05351094int:BSN
InteractionSNRNP200 interactions

CUL4A RBM45 HUWE1 HTRA4 CREBBP ACE2 UBE2O PAXBP1 RBM8A MTREX EP300

4.00e-0546010911int:SNRNP200
InteractionEIF3K interactions

DDX60 HUWE1 IFI16 EIF3CL UBE2O RBM8A EIF3D

4.03e-051711097int:EIF3K
InteractionDTL interactions

CUL4A FLG FBXO11 ACE2 PTPN3 PREX1

4.61e-051191096int:DTL
InteractionSIRT7 interactions

CUL4A TPR SRSF4 NUMA1 RECQL HUWE1 CKB UBE2O IGF2R SMARCA2 EIF3D MTREX CLUH PNP

4.83e-0574410914int:SIRT7
InteractionCSE1L interactions

RBM45 HUWE1 CREBBP CKB ACE2 UBE2O PTPRM MTREX EP300

5.26e-053141099int:CSE1L
InteractionDLGAP1 interactions

GRIN1 GRIN2B HUWE1 UBE2O PPP3CB NRXN1 BEGAIN

5.59e-051801097int:DLGAP1
InteractionPAX7 interactions

SSBP1 CREBBP SMARCA2 KDM2B CTTN EP300

5.80e-051241096int:PAX7
InteractionH2BC12 interactions

RBM45 NUMA1 ATL3 HUWE1 NEB ACE2 AEBP1 ANKRD11 MTREX

6.38e-053221099int:H2BC12
InteractionCTBP1 interactions

CUL4A FBXO11 GRIN1 CREBBP ACE2 IGF2R NISCH KDM2B EP300 CDC23

7.13e-0540610910int:CTBP1
InteractionCUL1 interactions

CUL4A FBXO40 RNMT SRSF4 IRF3 FBXO11 SSBP1 HUWE1 KMT2E CKB DLC1 KDM2B MTREX FBXO21 EP300

7.42e-0587610915int:CUL1
InteractionPRP4K interactions

SRSF4 RECQL HTRA4 PRPF18 PAXBP1 RBM8A CTTN CLUH EP300

7.52e-053291099int:PRP4K
InteractionHNF1B interactions

TET2 SSBP1 CREBBP EPC1 SMARCA2 KDM2B EP300

7.85e-051901097int:HNF1B
InteractionSOX7 interactions

TET2 CREBBP SMARCA2 KDM2B EP300

8.27e-05821095int:SOX7
InteractionH2BC4 interactions

TET2 NUMA1 HUWE1 NEB AEBP1 SMARCA2 ANKRD11 MTREX

8.29e-052591098int:H2BC4
InteractionEIF3B interactions

DDX60 ATL3 HUWE1 EIF3CL ACE2 PTPN3 RBM8A EIF3D EP300

9.04e-053371099int:EIF3B
InteractionEIF3E interactions

DDX60 NUMA1 HUWE1 HTRA4 EIF3CL RBM8A EIF3D EP300

9.22e-052631098int:EIF3E
InteractionMAPK3 interactions

CUL4A GRIN1 GRIN2B HTRA4 CPLX4 IFI16 CREBBP DLC1 DHPS CDC23

9.63e-0542110910int:MAPK3
InteractionANAPC5 interactions

CUL4A ATL3 HUWE1 CREBBP EP300 CDC23

1.05e-041381096int:ANAPC5
InteractionCDH2 interactions

CUL4A GRIN1 GRIN2B CREBBP ACE2 EPHA7

1.09e-041391096int:CDH2
InteractionTHOC3 interactions

HUWE1 ZKSCAN5 ACE2 UBE2O CLUH

1.10e-04871095int:THOC3
InteractionBRD2 interactions

NUMA1 KAT7 ACE2 TFPT UBE2O ARSB BRDT ZC3H4 CAPRIN2 SMARCA2

1.12e-0442910910int:BRD2
InteractionKPNA2 interactions

RNMT NUMA1 IRF3 RECQL HUWE1 IFI16 CREBBP ACE2 UBE2O SMARCA2 EP300

1.17e-0451910911int:KPNA2
InteractionXRCC6 interactions

CUL4A TPR RBM45 NUMA1 SSBP1 HUWE1 DYSF IFI16 CREBBP CKB ACE2 UBE2O ZC3H4 CLUH EP300

1.41e-0492810915int:XRCC6
InteractionPRMT1 interactions

TET2 TPR RNMT RBM45 HUWE1 IFI16 ACE2 UBE2O PAXBP1 ZC3H4 RBM8A EIF3D MTREX CTTN EP300

1.42e-0492910915int:PRMT1
InteractionRCN2 interactions

DDX60 HUWE1 IFI16 PTPN9 TFPT UBE2O SMARCA2 EP300

1.49e-042821098int:RCN2
InteractionRBM39 interactions

CUL4A SRSF4 RBM45 NUMA1 KMT2E IFI16 CKB UBE2O PAXBP1 PPP3CB RBM8A EIF3D MTREX CTTN PREX1 EP300

1.49e-04104210916int:RBM39
InteractionTXNIP interactions

TPR FLG NUMA1 HUWE1 UBE2O GET4 CTTN

1.55e-042121097int:TXNIP
InteractionWDR82 interactions

CUL4A IRF3 HUWE1 PPP3CB ZC3H4 CTTN EP300

1.60e-042131097int:WDR82
InteractionCAPN1 interactions

GRIN2B HUWE1 HTRA4 ZC3H4 OS9 MTREX EP300

1.69e-042151097int:CAPN1
InteractionNUP153 interactions

TPR NUMA1 RECQL HUWE1 HTRA4 IFI16 ACE2

1.74e-042161097int:NUP153
InteractionACTL6A interactions

NUMA1 RECQL HUWE1 TFPT BRDT EPC1 SMARCA2 EP300

1.76e-042891098int:ACTL6A
InteractionNUDT21 interactions

HUWE1 EIF3CL ACE2 BRDT P3H2 P3H1 MTREX CTTN EP300

1.79e-043691099int:NUDT21
InteractionUSP10 interactions

CUL4A KMT2E IFI16 ACE2 RBM8A EIF3D CLUH YTHDF3

1.81e-042901098int:USP10
InteractionHOXB4 interactions

CUL4A CREBBP EP300

1.91e-04211093int:HOXB4
InteractionCSNK2A1 interactions

FLG GRIN2B IFI16 CREBBP EIF3CL KAT7 TFPT UBE2O IGF2R ZC3H4 ANKRD11 KDM2B EIF3D MTREX EP300

1.94e-0495610915int:CSNK2A1
InteractionDDOST interactions

CUL4A ATL3 RECQL HUWE1 KAT7 ACE2 UBE2O EP300 YTHDF3

2.02e-043751099int:DDOST
InteractionSRRM2 interactions

SRSF4 IFI16 ACE2 PTPN3 UBE2O DHPS SMARCA2 RBM8A MTREX EP300

2.05e-0446210910int:SRRM2
InteractionNUP85 interactions

TPR NUMA1 RGPD1 HUWE1 IFI16 GET4

2.05e-041561096int:NUP85
InteractionPTPN3 interactions

ACE2 PTPN3 UBE2O PTPRM XPR1

2.11e-041001095int:PTPN3
InteractionERG interactions

TET2 NUMA1 HUWE1 CREBBP SMARCA2 KDM2B EP300

2.12e-042231097int:ERG
InteractionSHANK2 interactions

GRIN1 GRIN2B ACE2 CTTN

2.23e-04551094int:SHANK2
InteractionFUS interactions

CUL4A SRSF4 RBM45 NUMA1 GRIN1 SSBP1 CREBBP CKB ACE2 ZC3H4 MTREX CLUH EP300

2.26e-0475710913int:FUS
InteractionMDM2 interactions

CUL4A TPR RECQL HUWE1 IFI16 CREBBP ACE2 UBE2O SMARCA2 RAB15 MTREX EP300

2.31e-0465810912int:MDM2
InteractionKLF4 interactions

SSBP1 HUWE1 CREBBP SMARCA2 KDM2B EP300

2.35e-041601096int:KLF4
InteractionSFPQ interactions

TPR SRSF4 RBM45 HUWE1 IFI16 ACE2 UBE2O DHPS SMARCA2 CTTN EP300

2.38e-0456310911int:SFPQ
InteractionPNN interactions

SRSF4 DDX60 NUMA1 IFI16 ACE2 UBE2O BRDT RBM8A

2.38e-043021098int:PNN
InteractionRPS6KA1 interactions

GRIN1 GRIN2B CREBBP KAT7 PTPN3 DLC1 CTTN

2.43e-042281097int:RPS6KA1
InteractionSRSF5 interactions

TPR SRSF4 HUWE1 IFI16 ACE2 UBE2O PPP3CB EIF3D CLUH EP300

2.52e-0447410910int:SRSF5
InteractionEIF2S3 interactions

DDX60 IFI16 EIF3CL ACE2 UBE2O RBM8A EIF3D CLUH

2.54e-043051098int:EIF2S3
InteractionDDX5 interactions

CUL4A RBM45 NUMA1 IFI16 CREBBP PRPF18 ACE2 GET4 RBM8A MTREX EP300

2.56e-0456810911int:DDX5
InteractionLSM12 interactions

CUL4A HUWE1 IFI16 NRXN1 CLUH YTHDF3

2.69e-041641096int:LSM12
InteractionSNRPA interactions

CUL4A SRSF4 HUWE1 ACE2 PAXBP1 ZC3H4 RBM8A MTREX EP300 YTHDF3

2.87e-0448210910int:SNRPA
InteractionCTSD interactions

CUL4A HUWE1 IFI16 KAT7 IGF2R CST3

2.96e-041671096int:CTSD
InteractionMAF interactions

HUWE1 CREBBP UBE2O EP300

3.13e-04601094int:MAF
InteractionNXPH1 interactions

IGF2R NRXN1 OS9

3.25e-04251093int:NXPH1
InteractionALX1 interactions

RBM45 CREBBP EP300

3.25e-04251093int:ALX1
InteractionNUPR1 interactions

TPR SRSF4 NUMA1 RECQL SSBP1 KAT7 P3H1 RBM8A EIF3D MTREX CTTN EP300

3.25e-0468310912int:NUPR1
InteractionEGR2 interactions

TET2 CREBBP EPC1 SMARCA2 KDM2B EP300

3.36e-041711096int:EGR2
InteractionBMAL1 interactions

HUWE1 CREBBP TFPT UBE2O EP300

3.43e-041111095int:BMAL1
InteractionCTSB interactions

CUL4A HUWE1 IGF2R RNF103 CST3 OS9 YTHDF3

3.48e-042421097int:CTSB
InteractionCCNT2 interactions

RECQL HTRA4 BRDT CTTN

3.55e-04621094int:CCNT2
InteractionH3C1 interactions

CUL4A TPR NUMA1 RECQL NEB CREBBP TYMS KAT7 ACE2 ZC3H4 SMARCA2 KDM2B EP300 CDC23

3.56e-0490110914int:H3C1
InteractionEIF3D interactions

DDX60 CREBBP EIF3CL ACE2 RBM8A EIF3D EP300

3.66e-042441097int:EIF3D
InteractionH2AX interactions

NUMA1 SSBP1 HUWE1 NEB IFI16 ACE2 UBE2O P3H1 SMARCA2 KDM2B EP300

3.69e-0459310911int:H2AX
InteractionTBR1 interactions

TET2 BRDT SMARCA2 KDM2B EP300

3.73e-041131095int:TBR1
InteractionTAF15 interactions

CUL4A TET2 TPR NUMA1 ACE2 UBE2O PAXBP1 MTREX EP300

3.75e-044081099int:TAF15
InteractionACTC1 interactions

TPR FBXO40 RBM45 NUMA1 GRIN1 GRIN2B CKB UBE2O PAXBP1 ZC3H4 SMARCA2 CTTN

3.75e-0469410912int:ACTC1
InteractionRBM15 interactions

RECQL IFI16 ACE2 UBE2O CTTN EP300

3.81e-041751096int:RBM15
InteractionH2BC21 interactions

CUL4A NUMA1 RECQL HUWE1 NEB IFI16 CREBBP KAT7 PTPRM ZC3H4 P3H1 EP300

3.85e-0469610912int:H2BC21
InteractionPDCD4 interactions

CUL4A DDX60 CKB ZC3H4 RBM8A EP300

3.92e-041761096int:PDCD4
InteractionTEAD1 interactions

SSBP1 CREBBP SMARCA2 KDM2B CTTN EP300

3.92e-041761096int:TEAD1
InteractionPDIA6 interactions

HUWE1 IFI16 ACE2 UBE2O PTPRM P3H1 CTTN EP300

4.05e-043271098int:PDIA6
InteractionEIF3G interactions

DDX60 EIF3CL ACE2 UBE2O RBM8A EIF3D EP300

4.13e-042491097int:EIF3G
InteractionPPP3CA interactions

GRIN1 GRIN2B PPP3CB P3H1 RBM8A CLUH

4.29e-041791096int:PPP3CA
InteractionPSMD12 interactions

CUL4A HUWE1 HTRA4 IFI16 ACE2 PTPN9 PTPRM EIF3D

4.39e-043311098int:PSMD12
InteractionLGALS1 interactions

CHL1 PRTG ITGA1 CEMIP2 IGDCC4 ACE2 IGF2R CLUH

4.48e-043321098int:LGALS1
InteractionKEAP1 interactions

CUL4A TET2 RBM45 NUMA1 HUWE1 GET4 CTTN EP300

4.48e-043321098int:KEAP1
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP KAT7 EP300

3.05e-0517663486
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC28 RGPD1 TTC21B CFAP70 CDC23

6.26e-05115665769
GeneFamilyCD molecules|MRH domain containing

IGF2R OS9

1.95e-0466621233
GeneFamilyFerlin family

DYSF FER1L5

1.95e-046662828
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN1 GRIN2B

2.72e-0476621201
GeneFamilyFibronectin type III domain containing

CHL1 PRTG IGDCC4 PTPRM EPHA7

2.95e-04160665555
GeneFamilyCyclins|F-boxes other

FBXO40 FBXO11 FBXO21

3.87e-0439663560
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN3 PTPN9

1.93e-0318662812
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.93e-031866291
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CHL1 PRTG IGDCC4 PTPRM

2.84e-03161664593
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TTC28 CREBBP TDRD7 FCHSD2 PTPN9 IGF2R DLC1 PPP3CB PTPRM ZC3H4 SMARCA2 AKAP10 MTREX YTHDF3

1.28e-0585610914M4500
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_UP

CHL1 CDHR1 CP RECQL GRIN1 AKAP10 CDC23

1.61e-051921097M2776
CoexpressionHAY_BONE_MARROW_STROMAL

CHL1 LAPTM4A PRTG CP ITGA1 IGDCC4 HOXC6 DLC1 NRXN1 NRXN2 PTPRM P3H2 PRICKLE2

1.84e-0576710913M39209
CoexpressionGSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP

ANKRD13B TET2 TTC28 TDRD7 ACE2 NRXN2 SMARCA2

2.09e-052001097M9348
CoexpressionIWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_UP

CHL1 CDHR1 CP RECQL GRIN1 AKAP10 CDC23

2.86e-052101097MM751
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 TPR RNMT DDX60 KMT2E IFI16 PAXBP1 ANKRD11

3.68e-08200110812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 ITGA1 IGF2R NRXN1 NRXN2 CST3 BEGAIN

5.63e-0719511074a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 ITGA1 IGF2R NRXN1 NRXN2 CST3 BEGAIN

5.63e-0719511077a32a8535c29b819dacba901d0658280a2631c94
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 HUWE1 SLC7A14 CKB NRXN1 NISCH ANKRD11

5.63e-0719511073e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 HUWE1 SLC7A14 CKB NRXN1 NISCH ANKRD11

5.63e-0719511077796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 RAB3C CKB DLC1 NRXN1 NRXN2 PREX1

5.83e-071961107e874aa82a20bb59582c8cd7f8d30b2ed02903a85
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AFF2 DDX60 ACY1 NEB IFI16 RUFY2

2.16e-06152110618194f757d319958f26e5a91f56d89f25711236f
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 ITGA1 CKB IGF2R NRXN1 P3H2

4.12e-0617011061f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B RAB3C RAB15 BSN BEGAIN

5.37e-061781106a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B RAB3C RAB15 BSN BEGAIN

5.37e-0617811061bddbc083c36657bd6910f7466126ab325e88176
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CHL1 TET2 GRIN2B HTRA4 CEMIP2 SMARCA2

5.54e-06179110614fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

CP ITGA1 CEMIP2 FCHSD2 DLC1 PTPRM

7.57e-061891106c81787a8c662db5d7814c583dd64562857629e81
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GRIN1 GRIN2B SLC7A14 RAB3C RAB15 BSN

7.80e-061901106416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 ITGA1 CKB IGF2R NRXN1 CST3

7.80e-061901106951e067d14412db67dc3babcdf61e41717d7b429
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 ITGA1 CKB IGF2R NRXN1 BEGAIN

8.28e-061921106430ef714bf2544d32f3fd96a55af010f79aa9be0
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTC28 ITGA1 DYSF PTPRM PRICKLE2 PREX1

8.53e-061931106f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TTC28 ITGA1 DYSF CEMIP2 PTPRM PRICKLE2

9.31e-061961106ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

ITGA1 IFI16 CEMIP2 PTPRM PRICKLE2 PREX1

9.58e-06197110630dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell5'-Adult-Distal_Rectal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDHR1 CKB AEBP1 P3H2 CST3 CLUH

9.86e-061981106db26c20321f9ab102d6484f22ddb2bde684067b1
ToppCellcontrol-Epithelial|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CHL1 CP CKB PTPN3 CST3 CTTN

1.04e-052001106f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRPM6 AFF2 GRIN2B DYSF IGF2R

2.74e-051421105191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRPM6 AFF2 GRIN2B DYSF IGF2R

2.83e-051431105b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ITGA1 DPH6 ARSB MTREX CTTN

6.82e-05172110584d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellPSB-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AFF2 RAB3C DLC1 AEBP1 BEGAIN

8.02e-05178110545bdbb96094c97756e1b6eebd80eadd8472143f2
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B RAB3C RAB15 BEGAIN

8.23e-051791105a3922476f33d2e4137a12dbda21a1703dff79684
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CHL1 SLC7A14 RAB3C NRXN1 BSN

8.23e-051791105e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 ITGA1 DYSF PRICKLE2 PREX1

8.45e-051801105d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF CEMIP2 DLC1 PRICKLE2 AKAP10

8.67e-0518111054df7972f88117108698efd06b124b232f8588981
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDHR1 CP DYSF PTPN3 BSN

8.67e-051811105b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDHR1 CP DYSF PTPN3 BSN

8.67e-051811105cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF CEMIP2 DLC1 PRICKLE2 AKAP10

8.67e-051811105cbb530566893281289026bfd93adf721decd4ca3
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDHR1 CP DYSF PTPN3 BSN

8.67e-051811105ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRIN2B RAB3C CKB NRXN2 OS9

8.90e-051821105fa23d5bed1147a423c42bd30029a06963410b16e
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CHL1 RGPD1 GRIN2B CEMIP2 KDM2B

8.90e-0518211057b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKB TYMS DLC1 NRXN2 PREX1

9.61e-0518511050149981d3818a6250f32c08456c28e7037c39d91
ToppCellCOPD-Stromal-Pericyte|World / Disease state, Lineage and Cell class

AFF2 ITGA1 DLC1 AEBP1 PRICKLE2

9.86e-0518611058adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GRIN1 GRIN2B RAB3C RAB15 BSN

9.86e-0518611053f889083fcffe516388e9b03a5e23af2010ced33
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DYSF BTN2A2 PTPRM PRICKLE2 SMARCA2

1.01e-041871105ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDX60 ITGA1 DYSF BTN2A2 PTPRM

1.01e-041871105f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

TTC28 ITGA1 DYSF CEMIP2 PRICKLE2

1.01e-041871105f3548817f2fded5978137bb252cb628ac199e4f6
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRIN2B RAB3C CKB NRXN1 OS9

1.01e-04187110585645de9069bd9a8a02d53b0d3d73bf9c2b57189
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

TTC28 DYSF PTPRM PRICKLE2 PREX1

1.01e-041871105fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B RAB3C NRXN2 BSN

1.01e-041871105e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B RAB3C NRXN2 BSN

1.01e-04187110524cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B RAB3C NRXN2 BSN

1.01e-0418711052f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCPG1 SLC7A14 RAB3C ACE2 CST3

1.04e-041881105e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ITGA1 HUWE1 CEMIP2 IGF2R ANKRD11

1.04e-041881105ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTC28 ITGA1 DYSF PTPRM PRICKLE2

1.04e-041881105117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D122|Adult / Lineage, Cell type, age group and donor

ITGA1 DYSF CEMIP2 PTPRM PRICKLE2

1.04e-04188110502a62888e9db29d20133eeca1686d302545a39c9
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 SLC7A14 CKB NRXN1 NISCH

1.04e-041881105a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

TTC28 DYSF PTPRM PRICKLE2 PREX1

1.04e-0418811053953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 ITGA1 CKB IGF2R NRXN1

1.04e-041881105a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHL1 ITGA1 PTPRM PRICKLE2 PREX1

1.06e-041891105b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGA1 IGF2R DLC1 NRXN1 BEGAIN

1.06e-04189110526cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 IGDCC4 PTPN3 P3H2 PRICKLE2

1.06e-041891105aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 IGDCC4 PTPN3 P3H2 PRICKLE2

1.06e-0418911058977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 ITGA1 CKB IGF2R NRXN1

1.06e-041891105ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA1 CKB IGF2R NRXN1 BEGAIN

1.09e-041901105106862ef44fcaa0971c3ba0147d13eb08015ca77
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 ITGA1 DYSF PRICKLE2 PREX1

1.12e-0419111051de0bdfd13bd930691564c2673f2e66393bc0255
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 ITGA1 DYSF PRICKLE2 PREX1

1.14e-0419211057197e401e563441ab94815f7619e032ebef9e586
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CHL1 GRIN2B RAB3C RAB15 BSN

1.14e-0419211054c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA1 CEMIP2 DLC1 PTPRM PRICKLE2

1.14e-0419211054bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAB3C CKB TYMS DLC1 PREX1

1.17e-0419311054f4f430d7e1b65e19ca829f55ca93edeb6c1c85d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B SLC7A14 RAB15 BSN

1.17e-041931105461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B SLC7A14 RAB15 BSN

1.17e-0419311050dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEMIP2 HOXC6 DLC1 NRXN1 NRXN2

1.17e-0419311052483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

TTC28 ITGA1 DLC1 AEBP1 PRICKLE2

1.17e-041931105e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellThalamus-Neuronal|Thalamus / BrainAtlas - Mouse McCarroll V32

GRIN1 SLC7A14 PPP3CB RAB15 BSN

1.17e-041931105712a4acd1167e43543950bc819ff11984e6f718d
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTC28 ITGA1 DYSF PTPRM PRICKLE2

1.17e-041931105ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA1 CKB IGF2R NRXN1 CST3

1.17e-0419311057386fadc13a437f3b0c99b5d116cd3c5f893529c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAPTM4A ITGA1 CEMIP2 DLC1 SMARCA2

1.20e-0419411056115c20ffe414378508f3879e67815b6062341a7
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2|World / Primary Cells by Cluster

CHL1 SLC7A14 NRXN1 NRXN2 PTPRM

1.20e-041941105b42fd64b0fb95434a9e4e6586f31d26114a4074b
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-MGE2-10|World / Primary Cells by Cluster

CHL1 SLC7A14 NRXN1 NRXN2 PTPRM

1.20e-04194110581e7bc6516ab8d02ccd1c76a56a3533b788c27c8
ToppCellPND28-Endothelial-Endothelial_blood-vessel|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAPTM4A ITGA1 CEMIP2 DLC1 SMARCA2

1.20e-0419411056317e9cdf96eb020f84d50bf41f803db5c9c04a0
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA1 CEMIP2 DLC1 PTPRM SMARCA2

1.20e-0419411052c78e754cac848fd47172f94e392749eb0ab50d4
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA1 CEMIP2 DLC1 PTPRM PRICKLE2

1.20e-041941105f159ef8541d75a4e98468947f231bb463bec922c
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA1 CEMIP2 DLC1 PTPRM SMARCA2

1.20e-0419411051b382508453c5b08fb617f626b230adf3b6cff99
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTC28 ITGA1 DYSF PTPRM PRICKLE2

1.20e-04194110571ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA1 CEMIP2 DLC1 PTPRM SMARCA2

1.20e-04194110592a8e6e3e3f6fd9dacb723b58e7a8b63473e403e
ToppCellPND28-Endothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAPTM4A ITGA1 CEMIP2 DLC1 SMARCA2

1.20e-041941105b592c713204db7ae2f34a54f2d03d13834593c57
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTC28 ITGA1 DYSF PTPRM PRICKLE2

1.20e-04194110540842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA1 CKB IGF2R NRXN1 CST3

1.23e-0419511056e875c83f838241b5fcaf4a3249b1408d74521dc
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ITGA1 DYSF CEMIP2 PTPRM PNP

1.23e-0419511054658fb197657d7692ee344ae76b11b0210c418ba
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 GRIN2B SLC7A14 RAB15 BSN

1.23e-041951105ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CP DYSF FCHSD2 PREX1 XPR1

1.23e-041951105d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAB3C CKB DLC1 NRXN2 PREX1

1.23e-0419511059fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA1 CEMIP2 PTPRM PRICKLE2 MTREX

1.23e-0419511057f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGA1 CEMIP2 DLC1 PTPRM SMARCA2

1.23e-041951105cd011433b3b9bfb1adb13eca2f3f2a5db024cd94
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDHR1 CP CEMIP2 IGF2R EPHA7

1.26e-0419611057d5eaed189aa6116f3799be010139fb675ec65e0
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAPTM4A ITGA1 CKB NRXN1 CST3

1.26e-041961105acbb493dbb49a33f20cf11106363f7ed51209706
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

HUWE1 PTPN9 IGF2R SMARCA2 ANKRD11

1.26e-0419611057bced0cc2112697593c478fa291b8ed3941fb811
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHL1 CP CKB PTPN3 CTTN

1.26e-0419611053e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHL1 CP CKB PTPN3 CTTN

1.26e-0419611051efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 ITGA1 IGF2R NRXN1 CST3

1.26e-0419611056708026bafd19c35c5c4e81911344d36a0f508cd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

CHL1 GRIN2B DLC1 NRXN1 XPR1

1.29e-04197110579b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

TTC28 ITGA1 DYSF CEMIP2 PTPRM

1.29e-0419711057e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellnucseq-Endothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTC28 ITGA1 DYSF PTPRM PRICKLE2

1.29e-041971105ebf9be068eaa658493fa7884fd19f34642922acb
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

CHL1 GRIN2B DLC1 NRXN1 XPR1

1.29e-041971105d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCell5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDHR1 CKB P3H2 CST3 CLUH

1.29e-041971105e14a0e8a893c72356afc5508e3531ae0b23bfe16
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 SLC7A14 NRXN1 NRXN2 XPR1

1.29e-041971105f7eaac1c321710a55e09ffb047a7db2baf7b7e28
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

1.33e-0521082180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

1.33e-0521082cv:C4551859
DiseaseMenke-Hennekam syndrome

CREBBP EP300

1.33e-0521082cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

1.33e-0521082DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

1.33e-0521082cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

1.33e-0521082C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

1.33e-0521082DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

1.33e-0521082C0035934
DiseaseIntellectual Disability

CHL1 GRIN1 GRIN2B ACY1 KMT2E ACE2 NRXN1 NRXN2 DHPS

4.04e-054471089C3714756
DiseaseSmall cell carcinoma of lung

CREBBP CKB EP300 EPHA7

4.66e-05541084C0149925
Diseaseautism spectrum disorder (implicated_via_orthology)

GRIN1 CREBBP NRXN1 NRXN2 PREX1

2.47e-041521085DOID:0060041 (implicated_via_orthology)
DiseaseDrug toxicity

CP TYMS CST3 EPHA7

2.61e-04841084C0013221
DiseaseAdverse reaction to drug

CP TYMS CST3 EPHA7

2.61e-04841084C0041755
DiseaseAutism Spectrum Disorders

GRIN2B NRXN1 NRXN2 ANKRD11

2.74e-04851084C1510586
DiseaseInvoluntary Movements

CP GRIN1

2.75e-0471082C0427086
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

DYSF FER1L5

2.75e-0471082DOID:11724 (implicated_via_orthology)
Diseasecreatinine measurement

TET2 SPEGNB NEB RUFY2 PTPN3 PTPN9 IGF2R DLC1 NRXN2 ANKRD11 CFAP70 BSN

2.89e-0499510812EFO_0004518
Diseaseepilepsy (implicated_via_orthology)

CHL1 GRIN2B RAB3C PRICKLE2 BSN

3.41e-041631085DOID:1826 (implicated_via_orthology)
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN1 GRIN2B

3.66e-0481082DOID:3891 (biomarker_via_orthology)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN1 GRIN2B

3.66e-0481082DOID:1561 (biomarker_via_orthology)
DiseaseNeurodevelopmental Disorders

GRIN2B KMT2E ZC3H4 ANKRD11

3.86e-04931084C1535926
DiseaseAutistic Disorder

FBXO40 CP GRIN2B KMT2E NRXN1 NRXN2

4.07e-042611086C0004352
DiseaseEndomyocardial Fibrosis

ACE2 IGF2R

4.70e-0491082C0553980
Diseasevascular dementia (is_marker_for)

GRIN1 GRIN2B

7.14e-04111082DOID:8725 (is_marker_for)
Diseaseresponse to cisplatin, platinum measurement

FBXO11 DYSF NRXN1

9.78e-04531083EFO_0010154, GO_0072718
DiseaseDiffuse Large B-Cell Lymphoma

FBXO11 CREBBP EP300

1.09e-03551083C0079744
DiseaseSquamous cell carcinoma

CREBBP TYMS CTTN EP300

1.14e-031241084C0007137
Diseaseschizophrenia (biomarker_via_orthology)

GRIN2B PPP3CB

1.35e-03151082DOID:5419 (biomarker_via_orthology)
DiseaseLymphoma, Follicular, Grade 2

CREBBP TYMS

1.35e-03151082C1956132
DiseaseLymphoma, Follicular, Grade 3

CREBBP TYMS

1.35e-03151082C1956131
DiseaseLymphoma, Follicular, Grade 1

CREBBP TYMS

1.35e-03151082C1956130
Diseasemyelodysplastic syndrome (implicated_via_orthology)

TET2 CREBBP

1.35e-03151082DOID:0050908 (implicated_via_orthology)
DiseaseLymphoma, Large-Cell, Follicular

CREBBP TYMS

1.35e-03151082C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

CREBBP TYMS

1.35e-03151082C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

CREBBP TYMS

1.35e-03151082C0079758
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

DYSF FCHSD2 RNF103 CTTN

1.39e-031311084C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

DYSF FCHSD2 RNF103 CTTN

1.39e-031311084C4552091
DiseaseJuvenile arthritis

DYSF FCHSD2 RNF103 CTTN

1.39e-031311084C3495559
DiseaseJuvenile psoriatic arthritis

DYSF FCHSD2 RNF103 CTTN

1.39e-031311084C3714758
Diseasealcohol use disorder (is_implicated_in)

GRIN1 GRIN2B

1.54e-03161082DOID:1574 (is_implicated_in)
DiseaseJuvenile-Onset Still Disease

DYSF FCHSD2 RNF103 CTTN

1.55e-031351084C0087031
DiseaseDementia

CP CST3

1.74e-03171082C0497327
Diseaseheart disease (biomarker_via_orthology)

CP EP300

1.74e-03171082DOID:114 (biomarker_via_orthology)
DiseaseFEV/FEC ratio

TET2 RNMT ITGA1 NEB CEMIP2 KAT7 DLC1 BRDT PTPRM EPC1 ANKRD11 CTTN

1.80e-03122810812EFO_0004713
Diseasemagnesium measurement

TRPM6 TTC28 DLC1

1.85e-03661083EFO_0004845
Diseasep-tau:beta-amyloid 1-42 ratio measurement

TTC28 EPHA7

2.18e-03191082EFO_0007709
DiseaseAlzheimer disease, educational attainment

TET2 IGDCC4 NRXN1 SMARCA2 BSN

2.18e-032471085EFO_0011015, MONDO_0004975
Diseaseparental longevity

GRIN2B PRPF18 IGF2R PRICKLE2 SMARCA2 BSN EPHA7

2.31e-034941087EFO_0007796
DiseaseLymphoma, Follicular

CREBBP TYMS

2.42e-03201082C0024301
Diseaseprostate cancer (is_marker_for)

KMT2E SMARCA2 PREX1 EP300

2.63e-031561084DOID:10283 (is_marker_for)
Diseasenicotine dependence symptom count, depressive symptom measurement

GRIN2B P3H2 PREX1

2.66e-03751083EFO_0007006, EFO_0009262
Diseaseotitis media (implicated_via_orthology)

FBXO11 NISCH

2.92e-03221082DOID:10754 (implicated_via_orthology)
DiseaseHepatolenticular Degeneration

CP PPP3CB

3.48e-03241082C0019202
DiseaseHepatic Form of Wilson Disease

CP PPP3CB

3.48e-03241082C1527352
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

TET2 DYSF CKB TTC21B BSN PREX1

3.50e-033981086EFO_0003756, EFO_0003888, EFO_0004337

Protein segments in the cluster

PeptideGeneStartEntry
MEKEQAYTDAALNYE

TTC21B

1241

Q7Z4L5
YARKVEGDMYESANN

EP300

611

Q09472
KRYNLGDYNGEIMSE

EPC1

271

Q9H2F5
AQDMDAYTLAKAYFD

CDC23

81

Q9UJX2
TARYNFYVKAEDMEG

CDHR1

541

Q96JP9
FLEADAYGVSYNMKA

ANKRD11

1396

Q6UB99
AYGVSYNMKADIEDE

ANKRD11

1401

Q6UB99
MDNQEYKDAYKFAAD

BRDT

326

Q58F21
NQELEDKLYRMGQHY

BEGAIN

71

Q9BUH8
YDGQEAQNDAMILYD

AKAP10

426

O43572
RLNMQTGATEDDYYD

AEBP1

416

Q8IUX7
DDSVHNADYYMQEAK

AFF2

1066

P51816
AENQVGSDELDSYMY

DPH6

36

Q7L8W6
AYAKKVEGDMYESAN

CREBBP

631

Q92793
EEGVYDYENTGRMTQ

FLG

211

P20930
YQKARGMDNVEYQFA

IGDCC4

466

Q8TDY8
GQQLAKEYGMDFYET

RAB15

136

P59190
EQDYYSNMRQEALGH

RBM45

201

Q8IUH3
YETYKEAQAAMEGLN

RBM8A

121

Q9Y5S9
RYGQKDSSDQNFDYM

RAB3C

16

Q96E17
QNLDYYQTMSGVKEA

P3H1

181

Q32P28
GNEDYINASYVNMEI

PTPN3

691

P26045
DYINASFMDGYKQKN

PTPN9

356

P43378
EMVNGYEAKVYGASN

ANKRD13B

266

Q86YJ7
EDFQESNRMYSVNGY

CP

251

P00450
DQLKFKGNRMDYYNA

FBXO21

271

O94952
YYNGLKVLNMAAEND

NRXN1

266

P58400
EKYMEHRQTYGNTRE

KAT7

281

O95251
YMSQKGDLYFANVEE

CHL1

181

O00533
GRYYALKSMTEAEQQ

CKB

171

P12277
VIGNYYSSERMADNA

LAPTM4A

66

Q15012
VYEQQKYYGMSSRDA

BSN

3416

Q9UPA5
QDNRMNEGDAYYLLK

DDX60

1656

Q8IY21
AMYKYRNRDEGSYQV

NRXN2

1656

Q9P2S2
MDRYEEANNNQYSEG

KMT2E

281

Q8IZD2
YYNGLKVLNMAAEND

NRXN1

1271

Q9ULB1
MESYNAGVKHYEADD

P3H2

211

Q8IVL5
RYILMAFQNSEYGDD

PAXBP1

806

Q9Y5B6
MFGYTVQQYENEEGK

ITGA1

46

P56199
KMERYKDNFTAAGYN

EPHA7

936

Q15375
QDMGDDVYQQYRSLT

HUWE1

1981

Q7Z6Z7
AYSVHYMKAEGLNNE

PRTG

451

Q2VWP7
DYGSNSFYQEKDMLS

HOXC6

71

P09630
MYKYRNRDEGSYQVD

NRXN2

611

P58401
SREEPYHYGNKMEQN

PRICKLE2

396

Q7Z3G6
AQGMSREEYEEYQKQ

CPLX3

36

Q8WVH0
FRDQKDGYRKNEGYM

EIF3CL

886

B5ME19
FKYGDAERRFYEQMN

EEF1DP3

16

Q658K8
AAQGMTREEYEEYQK

CPLX4

36

Q7Z7G2
DYLRNMKEYEVDNDG

CCPG1

706

Q9ULG6
DMDYVQIDATINYGN

HTRA4

311

P83105
AMEGKDFNYEYVQRE

KDM2B

86

Q8NHM5
KGRENMLYYDTIEDA

FBXO11

261

Q86XK2
AKAEEYLQQAAQMDY

CFAP70

946

Q5T0N1
ANANLMRNGADYAVY

DHPS

291

P49366
DRDYMERDKDNPNQY

CUL4A

741

Q13619
DDMDKNEIASVAYRY

EIF3D

346

O15371
LKNEMARANHYEDYG

ACE2

186

Q9BYF1
SVTGYKDAYVGRMDN

CEMIP2

956

Q9UHN6
AASAKDIYYNNMEEV

ATL3

356

Q6DD88
NRRYMTEVDYSNKQG

CAPRIN2

371

Q6IMN6
AVDAKDYNMYLVHNG

FBXO40

301

Q9UH90
EFTYYEIQDNTGKME

IFI16

701

Q16666
DYEHAAKYMKNSQVR

RNMT

436

O43148
FRDGEEVATGYKNMY

ARSB

196

P15848
GVKADDRNDYRSMYP

FCHSD2

71

O94868
DYEAGDVSFYNMRDR

BTN2A2

451

Q8WVV5
EAQDAGYRMYRKSQT

PPP3CB

291

P16298
KGRSYGSYNTNEDME

RNF103

591

O00237
IYMSDNYTDVNGEKV

DYSF

966

O75923
MENGYTYEDYKNTAE

PNP

1

P00491
AVGEYNKASNDMYHS

CST3

56

P01034
DENRMKNRYGNIIAY

PTPRM

921

P28827
RYEDSQQEEAQYGAM

NUMA1

816

Q14980
KMGRGLNSSYDQQEY

RGPD1

576

P0DJD0
DQYKAYLQDLVEGMD

IRF3

406

Q14653
SGDMRTNGDNYLYEI

IGF2R

2161

P11717
KDYMRQAGEVTYADA

SRSF4

121

Q08170
QMIYGNGAESKNYEE

NUGGC

201

Q68CJ6
TYKHSRQGLDEMYNE

RUFY2

286

Q8WXA3
AKQDVDDEYSMQYSA

SMARCA2

681

P51531
LRQGDTAVYAEMYEN

FER1L5

776

A0AVI2
RASVEKGDYYEAHQM

GET4

31

Q7L5D6
KNEQVMYRFRYDDGT

PREX1

486

Q8TCU6
GKYEVYVENSLGMDQ

SPEGNB

216

A0A087WV53
RYVGKDYSAAQELME

TDRD7

481

Q8NHU6
AAAAVYREMYRNEDG

NDUFAF5

281

Q5TEU4
VNYEGQSAYDVADML

DLC1

1136

Q96QB1
MAYVQRQADSKQYGD

OS9

256

Q13438
DSEGYIYARGAQDMK

ACY1

101

Q03154
YIMGDYAEALSNQQK

CLUH

1031

O75153
REEMTDNTGYVSGYK

TPPP2

146

P59282
ENYYQESGRAGRDDM

RECQL

396

P46063
DKGFYYQQMSDAKAN

SLC7A14

726

Q8TBB6
QYEAFKDMLYSAQDQ

XPR1

21

Q9UBH6
VAEMKSVVDYNAYAG

YTHDF3

476

Q7Z739
EKYMTGEFRKYNNNN

TRPM6

1876

Q9BX84
MRVLDSYGDDYRASQ

TFPT

121

P0C1Z6
NQKYREMYEEFQDVG

MTREX

196

P42285
YSMEAADYREASSQQ

CTTN

446

Q14247
ASKRYEMLQDNVEGY

TPR

721

P12270
YGEYMDKNNVRRQAT

SSBP1

116

Q04837
VYSDKRMVQTAAGDY

NISCH

861

Q9Y2I1
QEGYENSRCYNEMAL

UBE2O

1091

Q9C0C9
YRDMESDYSGQGVDQ

TYMS

146

P04818
DSKSYGMYEDYENEQ

ZC3H4

186

Q9UPT8
GNAYNALGMYDQAVK

TTC28

521

Q96AY4
ALGMYDQAVKYHRQE

TTC28

526

Q96AY4
SSERYLKQNEMNGAY

TET2

366

Q6N021
EYVKANDAYLQMAIG

PRPF18

261

Q99633
DRKENYGSITSMGYE

ZKSCAN5

246

Q9Y2L8
YDAAVLNYMAGRDEG

GRIN2B

731

Q13224
KVNAYNISENMYKAD

NEB

1041

P20929
MQIQSDNQYKADYAD

NEB

1916

P20929
DNQYKADYADFMKGI

NEB

1921

P20929
NEDGDRKFANYSIMN

GRIN1

341

Q05586