Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ZINC_FINGER_C2H2_2	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZNF280C ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	1.12e-03	775	89	11	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZNF280C ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	1.14e-03	777	89	11	PS00028
Domain	Znf_C2H2-like	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZNF280C ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	1.39e-03	796	89	11	IPR015880
Domain	-	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	1.44e-03	679	89	10	3.30.160.60
Domain	Znf_C2H2	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZNF280C ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	1.52e-03	805	89	11	IPR007087
Domain	ZnF_C2H2	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZNF280C ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	1.56e-03	808	89	11	SM00355
Domain	KRAB	ZNF630 ZNF26 ZNF555 ZNF268 ZFP14 ZFP69B ZNF891	1.61e-03	358	89	7	PS50805
Domain	KRAB	ZNF630 ZNF26 ZNF555 ZNF268 ZFP14 ZFP69B ZNF891	1.61e-03	358	89	7	PF01352
Domain	zf-C2H2	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	1.68e-03	693	89	10	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	1.70e-03	694	89	10	IPR013087
Domain	KRAB	ZNF630 ZNF26 ZNF555 ZNF268 ZFP14 ZFP69B ZNF891	1.91e-03	369	89	7	SM00349
Domain	KRAB	ZNF630 ZNF26 ZNF555 ZNF268 ZFP14 ZFP69B ZNF891	1.94e-03	370	89	7	IPR001909
Domain	zf-C2H2_6	ZNF26 ZNF555 ZFP14 ZFP69B ZNF236 ZNF891	3.89e-03	314	89	6	PF13912
Domain	Cupredoxin	PRPF8 HEPH	4.87e-03	22	89	2	IPR008972
Pubmed	Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13.	PDS5B N4BP2L2 ARPC2	1.06e-06	8	94	3	8812419
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	STK4 CDKL5 PNPLA6 AP1G1 DOCK8 ACO2 SCAMP1 RPS17 SSB PLEKHA7 NOS1 THRAP3 CNP LRRFIP2 ARPC2	6.67e-06	1431	94	15	37142655
Pubmed	Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescence.	CDKN1A HNF4A	7.23e-06	2	94	2	31695151
Pubmed	The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis.	SFRP1 DKK1	7.23e-06	2	94	2	23698475
Pubmed	p21CIP-1/WAF-1 induction is required to inhibit prostate cancer growth elicited by deficient expression of the Wnt inhibitor Dickkopf-1.	CDKN1A DKK1	7.23e-06	2	94	2	21098705
Pubmed	BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer.	CDKN1A PBRM1	7.23e-06	2	94	2	18339845
Pubmed	Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial.	SFRP1 DKK1	7.23e-06	2	94	2	28178355
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	STK4 PDS5B POLR3B PNPLA6 AP1G1 ACO2 ANXA5 RPF2 ANKRD17 RPS17 VTA1 PRPF8 THRAP3 CNP	1.62e-05	1353	94	14	29467282
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PDS5B CDK5RAP3 POLR3B AP1G1 ANKRD17 RPS17 VTA1 PRPF8 MAP3K4 ARPC2	2.12e-05	704	94	10	29955894
Pubmed	Activation of p21CIP1/WAF1 gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha.	CDKN1A HNF4A	2.16e-05	3	94	2	15541721
Pubmed	Nitric oxide is an activity-dependent regulator of target neuron intrinsic excitability.	KCNB2 NOS1	2.16e-05	3	94	2	21791288
Pubmed	Mutations in MAP3K1 that cause 46,XY disorders of sex development disrupt distinct structural domains in the protein.	MAP3K1 MAP3K4	2.16e-05	3	94	2	30608580
Pubmed	BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21.	CDKN1A PBRM1	2.16e-05	3	94	2	26992241
Pubmed	c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1.	SFRP1 DKK1	2.16e-05	3	94	2	17485441
Pubmed	INMAP overexpression inhibits cell proliferation, induces genomic instability and functions through p53/p21 pathways.	CDKN1A POLR3B	2.16e-05	3	94	2	25635878
Pubmed	Gremlin 1, frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis.	SFRP1 DKK1	2.16e-05	3	94	2	22576962
Pubmed	Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity.	CDKN1A ANXA5 BHLHE40	2.45e-05	21	94	3	21040902
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B PBRM1 AP1G1 ACO2 ANXA5 ZNF280C RPF2 RPS17 SSB PRPF8 PLEKHA7 THRAP3 LRRFIP2 ARPC2	2.86e-05	1425	94	14	30948266
Pubmed	Medulloblastoma comprises four distinct molecular variants.	SFRP1 DKK1	4.32e-05	4	94	2	20823417
Pubmed	Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation.	MAP3K1 MAP3K4	4.32e-05	4	94	2	12878610
Pubmed	MST kinases monitor actin cytoskeletal integrity and signal via c-Jun N-terminal kinase stress-activated kinase to regulate p21Waf1/Cip1 stability.	CDKN1A STK4	4.32e-05	4	94	2	19822666
Pubmed	Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery.	HRH1 CNP	4.32e-05	4	94	2	27671734
Pubmed	Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse.	DKK1 AP1G1 HNF4A	5.34e-05	27	94	3	31308417
Pubmed	Diverse Functions of Retinoic Acid in Brain Vascular Development.	SFRP1 RARG DKK1	5.96e-05	28	94	3	27445154
Pubmed	LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development.	CDKN1A STK4 HNF4A	6.64e-05	29	94	3	27358050
Pubmed	Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate.	CDKN1A DKK1 HNF4A	6.64e-05	29	94	3	18038450
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	CDKN1A STK4 DKK1 HRH1 HNF4A MAP3K1 MAP3K4	6.86e-05	371	94	7	25241761
Pubmed	Expression profile of WNT molecules in prostate cancer and its regulation by aminobisphosphonates.	SFRP1 DKK1	7.19e-05	5	94	2	21344486
Pubmed	Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter.	CDKN1A HNF4A	7.19e-05	5	94	2	17885207
Pubmed	Conditional ablation of the Notch2 receptor in the ocular lens.	CDKN1A SFRP1 DKK1	8.14e-05	31	94	3	22173065
Pubmed	p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.	CDKN1A HNF4A	1.08e-04	6	94	2	11172041
Pubmed	MEKK1/MEKK4 are responsible for TRAIL-induced JNK/p38 phosphorylation.	MAP3K1 MAP3K4	1.08e-04	6	94	2	21152872
Pubmed	Tumor susceptibility of p21(Waf1/Cip1)-deficient mice.	CDKN1A CNP	1.50e-04	7	94	2	11507077
Pubmed	A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida.	MAP3K1 MAP3K4	1.50e-04	7	94	2	17681137
Pubmed	Oligomerization of human Gadd45a protein.	CDKN1A MAP3K4	1.50e-04	7	94	2	11498536
Pubmed	A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity.	LHX3 NOS1	1.50e-04	7	94	2	14766174
Pubmed	Stimulation of Ly-6G on neutrophils in LPS-primed mice induces platelet-activating factor (PAF)-mediated anaphylaxis-like shock.	HRH1 PTAFR	1.50e-04	7	94	2	22131343
Pubmed	Diverse expression patterns of LIM-homeodomain transcription factors (LIM-HDs) in mammalian inner ear development.	LHX3 LHX9	1.50e-04	7	94	2	18942141
Pubmed	Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat.	TBC1D1 PTAFR	1.50e-04	7	94	2	12107726
Pubmed	G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells.	MAP3K1 MAP3K4	2.00e-04	8	94	2	18187455
Pubmed	Functional proteomics mapping of a human signaling pathway.	USP13 PBRM1 DKK1 AP1G1 DOCK8 EXPH5 TBC1D1 ZNF76	2.05e-04	591	94	8	15231748
Pubmed	Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.	AP1G1 ACO2 ANXA5 PRPF8 THRAP3	2.07e-04	198	94	5	24337577
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	EEFSEC PDS5B POLR3B PBRM1 CENPE SSB PRPF8 MAP3K1 LRRFIP2	2.18e-04	759	94	9	35915203
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	EEFSEC PNPLA6 AP1G1 RPS17 PRPF8 PLEKHA7 THRAP3 CNP	2.30e-04	601	94	8	33658012
Pubmed	Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells.	LHX3 NOS1	2.57e-04	9	94	2	25868900
Pubmed	ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway.	MAP3K1 MAP3K4	2.57e-04	9	94	2	19270716
Pubmed	Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.	MAP3K1 MAP3K4	2.57e-04	9	94	2	15866172
Pubmed	Genetic variations strongly influence phenotypic outcome in the mouse retina.	SFRP1 RARG THRAP3	2.67e-04	46	94	3	21779340
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	PBRM1 ZNF280C RPF2 RPS17 PRPF8 THRAP3	2.82e-04	330	94	6	33301849
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	STK4 PDS5B PBRM1 CENPE SNX24 ANXA5 SSB PRPF8 THRAP3 TUFT1 LRRFIP2	2.88e-04	1155	94	11	20360068
Pubmed	Defining the membrane proteome of NK cells.	CDK5RAP3 PNPLA6 AP1G1 CENPE DOCK8 ANXA5 ANKRD17 RPS17 PRPF8 GPAT4 CNP	3.16e-04	1168	94	11	19946888
Pubmed	Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.	MAP3K1 MAP3K4	3.21e-04	10	94	2	21559298
Pubmed	Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j mice.	HRH1 SSB	3.21e-04	10	94	2	10051620
Pubmed	Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.	SFRP1 DKK1 HNF4A	3.22e-04	49	94	3	19562671
Pubmed	BAALC potentiates oncogenic ERK pathway through interactions with MEKK1 and KLF4.	AP1G1 MAP3K1	3.91e-04	11	94	2	26050649
Pubmed	Cdk5 selectively affects the migration of different populations of neurons in the developing spinal cord.	LHX3 NOS1	3.91e-04	11	94	2	17492640
Pubmed	Ablation of Dido3 compromises lineage commitment of stem cells in vitro and during early embryonic development.	CDKN1A HNF4A	4.69e-04	12	94	2	21660050
Pubmed	Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists.	CDKN1A SFRP1	4.69e-04	12	94	2	27713059
Pubmed	Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes.	LHX3 LHX9	4.69e-04	12	94	2	15053981
Pubmed	FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development.	AP1G1 SSB	4.69e-04	12	94	2	29142217
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	PBRM1 PNPLA6 RPF2 ANKRD17 RPS17 SSB PRPF8 THRAP3 LRRFIP2	4.85e-04	847	94	9	35850772
Pubmed	Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns.	CDKN1A LHX3 NOS1	5.30e-04	58	94	3	27568519
Pubmed	SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis.	SFRP1 DKK1	5.53e-04	13	94	2	21490069
Pubmed	The zinc finger gene Fezf2 is required for the development of excitatory neurons in the basolateral complex of the amygdala.	NOS1 LHX9	5.53e-04	13	94	2	24723342
Pubmed	Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis.	STK4 HNF4A	5.53e-04	13	94	2	29712669
Pubmed	Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans.	NOS1 LHX9	6.44e-04	14	94	2	12379852
Pubmed	Several common variants modulate heart rate, PR interval and QRS duration.	CDKN1A DKK1	6.44e-04	14	94	2	20062063
Pubmed	Nuclear receptor NR5A2 is required for proper primitive streak morphogenesis.	DKK1 HNF4A	6.44e-04	14	94	2	17075876
Pubmed	p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease.	CDKN1A NOS1	6.44e-04	14	94	2	18786355
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	EEFSEC PDS5B ACO2 VTA1 SSB PRPF8 THRAP3 CNP	6.97e-04	711	94	8	33022573
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	CDK5RAP3 DNAJC28 CENPE AASS ACO2 RPF2 TRMT11 VTA1 SSB ZDHHC17 GPAT4 CNP	7.04e-04	1496	94	12	32877691
Pubmed	Lack of aspartoacylase activity disrupts survival and differentiation of neural progenitors and oligodendrocytes in a mouse model of Canavan disease.	CDKN1A CNP	7.42e-04	15	94	2	19739253
Pubmed	PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development.	PBRM1 CNP	7.42e-04	15	94	2	37371026
Pubmed	Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings.	SFRP1 DKK1	7.42e-04	15	94	2	17481602
Pubmed	MAP3Ks as central regulators of cell fate during development.	MAP3K1 MAP3K4	7.42e-04	15	94	2	18855897
Pubmed	A census of human transcription factors: function, expression and evolution.	ZNF26 RARG ZNF268 ZNF76 LHX3 ZNF236 HNF4A BHLHE40 LHX9	7.96e-04	908	94	9	19274049
Pubmed	Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse.	SFRP1 DKK1	8.46e-04	16	94	2	18257070
Pubmed	Transcription factor Sp3 is essential for post-natal survival and late tooth development.	CDKN1A TUFT1	8.46e-04	16	94	2	10675334
Pubmed	Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development.	LHX3 NOS1	8.46e-04	16	94	2	19800948
Pubmed	Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina.	LHX3 LHX9	8.46e-04	16	94	2	24333658
Pubmed	Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients.	CDKN1A DKK1	8.46e-04	16	94	2	35421372
Pubmed	Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia.	ACO2 ANXA5 SSB	9.18e-04	70	94	3	35008187
Pubmed	Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.	CDKN1A DKK1	9.57e-04	17	94	2	21076409
Pubmed	Ectodermal Wnt/β-catenin signaling shapes the mouse face.	CDKN1A DKK1	9.57e-04	17	94	2	21087601
Pubmed	Sonic hedgehog expressing and responding cells generate neuronal diversity in the medial amygdala.	NOS1 LHX9	9.57e-04	17	94	2	20507551
Pubmed	Hoxc10 and Hoxd10 regulate mouse columnar, divisional and motor pool identity of lumbar motoneurons.	LHX3 NOS1	9.57e-04	17	94	2	18065432
Pubmed	Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk.	S100Z ARPC2	9.57e-04	17	94	2	19861958
Pubmed	Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.	LHX3 NOS1	1.08e-03	18	94	2	31969659
Pubmed	Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification.	DKK1 HNF4A	1.08e-03	18	94	2	27521049
Pubmed	Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo.	SFRP1 DKK1	1.08e-03	18	94	2	22166339
Pubmed	Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors.	CDKN1A DKK1	1.08e-03	18	94	2	32243674
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	CDKN1A STK4 CABLES2 SNX24 RPS17 THRAP3	1.15e-03	432	94	6	23455922
Pubmed	ARPC1B promotes mesenchymal phenotype maintenance and radiotherapy resistance by blocking TRIM21-mediated degradation of IFI16 and HuR in glioma stem cells.	ANXA5 RPS17 LRRFIP2	1.17e-03	76	94	3	36380368
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	EEFSEC PBRM1 DKK1 ANXA5 ANKRD17 SSB PRPF8 THRAP3 CNP MAP3K1 LRRFIP2	1.19e-03	1371	94	11	36244648
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PBRM1 CENPE ANKRD17 LMTK3 NOS1 THRAP3 CNP LRRFIP2 ARPC2	1.20e-03	963	94	9	28671696
Pubmed	Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation.	SFRP1 DKK1	1.20e-03	19	94	2	12490556
Pubmed	Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges.	SFRP1 DKK1	1.20e-03	19	94	2	27671872
Pubmed	The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice.	CDKN1A DKK1	1.33e-03	20	94	2	21248711
Pubmed	Chromatin-remodeling factor, RSF1, controls p53-mediated transcription in apoptosis upon DNA strand breaks.	CDKN1A CNP	1.33e-03	20	94	2	30348983
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	LHX3 NOS1	1.33e-03	20	94	2	35177643
Cytoband	12q24.33	ZNF26 ZNF268 ZNF891	1.34e-04	48	94	3	12q24.33
Cytoband	8p11.21	SFRP1 GPAT4	8.49e-04	21	94	2	8p11.21
Cytoband	11q23.1	BCO2 FDXACB1	2.64e-03	37	94	2	11q23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr18q23	ATP9B ZNF236	3.08e-03	40	94	2	chr18q23
Cytoband	15q26.3	ARRDC4 OR4F6	3.23e-03	41	94	2	15q26.3
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF438 ZNF630 ZNF26 ZNF555 ZNF268 ZFP14 ZNF76 ZFP69B ZNF236 ZNF891	8.50e-05	718	58	10	28
GeneFamily	LIM class homeoboxes	LHX3 LHX9	6.54e-04	12	58	2	522
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K1 MAP3K4	2.67e-03	24	58	2	654
Coexpression	GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN	CDKN1A AP1G1 AASS ANXA5 TRPC5 BHLHE40 MAP3K1	7.38e-06	200	93	7	M5135
Coexpression	GSE360_CTRL_VS_T_GONDII_MAC_UP	CDKN1A ZNF268 ANXA5 ATP9B PTAFR KCNB2 ARPC2	7.38e-06	200	93	7	M5162
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	CDKN1A ZNF438 HRH1 PTAFR TUFT1 MAP3K1	9.62e-07	155	94	6	84221a285277292f7225eb69508c887541abeed1
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	IPPK CDKL5 ZNF630 ZNF268 ZDHHC17 ZNF891	1.65e-06	170	94	6	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	IPPK CDKL5 ZNF630 ZNF268 ZDHHC17 ZNF891	1.82e-06	173	94	6	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PNPLA6 DOCK8 ARRDC4 ANXA5 PTAFR ARPC2	3.86e-06	197	94	6	aec598543d9a6bd20670bc9855d6531a5ba995fa
Disease	RENAL CELL CARCINOMA, NONPAPILLARY	PBRM1 FLCN	1.87e-04	7	89	2	144700
Disease	Nonpapillary renal cell carcinoma	PBRM1 FLCN	1.87e-04	7	89	2	cv:CN074294
Disease	Malignant neoplasm of breast	ZNF438 SFRP1 PBRM1 RARG GFRAL DKK1 KCNT2 KCNH1 ACO2 TRMT11 MAP3K1	3.85e-04	1074	89	11	C0006142
Disease	hemopexin measurement	KCNT2 LHX9	4.86e-04	11	89	2	EFO_0008149
Disease	neurodegenerative disease (implicated_via_orthology)	STK4 PNPLA6 ACO2 TRPC5	9.88e-04	145	89	4	DOID:1289 (implicated_via_orthology)
Disease	level of Sterol ester (27:1/18:1) in blood serum	ANKRD17 HNF4A	1.05e-03	16	89	2	OBA_2045195
Disease	serum alanine aminotransferase measurement	CDKN1A PDS5B SLC13A1 EXPH5 N4BP2L2 ZNF76 HNF4A MAP3K1 OR4F6	1.24e-03	869	89	9	EFO_0004735
Disease	epilepsy (implicated_via_orthology)	KCNT2 SLC13A1 KCNH1 NOS1	1.52e-03	163	89	4	DOID:1826 (implicated_via_orthology)
Disease	glaucoma (is_marker_for)	HNF4A HEPH	1.65e-03	20	89	2	DOID:1686 (is_marker_for)
Disease	Ovarian Serous Adenocarcinoma	CDKL5 MAP3K4	2.18e-03	23	89	2	C1335177
Disease	level of Sterol ester (27:1/18:2) in blood serum	ANKRD17 HNF4A	2.79e-03	26	89	2	OBA_2045194
Disease	Neurodevelopmental Disorders	CDKL5 DOCK8 KCNH1	2.83e-03	93	89	3	C1535926

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRNKIAGYVTHLMKR	RPS17	46	P08708
GATTSVFPYNHRMKK	ACO2	291	Q99798
FVKFTHDQIMRRYGT	AKIRIN1	171	Q9H9L7
KRRQTSMTDFYHSKR	CDKN1A	141	P38936
VKNKERGTLLTTHYM	ABCA10	1386	Q8WWZ4
AHMYQVYKSRRGIKR	BHLHE40	31	O14503
YIHTRMRAKTSDFLK	ARPC2	261	O15144
MSRKTYAFFSHTIKA	AASS	101	Q9UDR5
RSVSHLRKVFDKYMT	ANXA5	201	P08758
MAAFRKGHVKVVRYL	ANKRD17	1391	O75179
QFRMAKGTVTYRSKF	BCO2	111	Q9BYV7
QTYLASGKTKTIRHM	ARRDC4	236	Q8NCT1
MAHSKTRTNDGKITY	PDS5B	1	Q9NTI5
KGFFRRSIQKNMVYT	RARG	111	P13631
YSGNKQRMHFALKSL	IPPK	186	Q9H8X2
YSNNRLIKMHEKVGS	MORC1	371	Q86VD1
HGSTYSLKRVEMKIR	ANGPTL7	326	O43827
QLRMRIKLTYNHKGS	AP1G1	791	O43747
FYGRKIMRKVSQSTS	PNPLA6	106	Q8IY17
RIQNGSYKSIHAMAK	PBRM1	236	Q86U86
HKNRTLKYLRMTGNK	LRRC34	176	Q8IZ02
QMRRTLHKAFKGSIF	SSB	141	P05455
GLSKTYKSHLMSTVR	FLCN	556	Q8NFG4
QVKGRIYSKFHQKRM	MMS22L	506	Q6ZRQ5
RYTQAKLSMHDRSLK	ATP9B	706	O43861
RKRKMVSFHGDVTVY	LMTK3	1346	Q96Q04
KGFFRRSVRKNHMYS	HNF4A	81	P41235
RTSFKHHQLRTMKSY	LHX9	271	Q9NQ69
MIYDLFRKHKTISFG	OR4F6	81	Q8NGB9
YSMRKLSSHIFKSRK	OR4K3	296	Q96R72
YFGIIRNRMMSTHKS	DNAJC28	31	Q9NX36
MTVGEYRHLANSKKY	KDM4D	96	Q6B0I6
KLSGYHRAEVMQKSS	KCNH1	51	O95259
RVFSRKDTSKMYIPH	EXPH5	771	Q8NEV8
QYFRNMKRSRGGSKS	LHX3	226	Q9UBR4
VKNRMKHLGLSTVGY	KCNT2	1056	Q6UVM3
LSIRSVGSHRYDMFK	LRRFIP2	101	Q9Y608
HRYRMTSDGTLFIKN	HMCN1	656	Q96RW7
YSSIKRFGSKAHMER	NOS1	371	P29475
FTSILNFYRTGKLHM	KCNB2	96	Q92953
SIVNKDHKRMFGTYF	DOCK8	1781	Q8NF50
TLSNVKGMALYTRKH	GFRAL	321	Q6UXV0
LYSKMIVGNHKDRSR	GPAT4	441	Q86UL3
STKNIFGRYSSQRMK	CDK5RAP3	81	Q96JB5
MNRGFSRKSHTFLPK	CNP	1	P09543
RRMAKYFSTPNKSFH	GPR156	326	Q8NFN8
YVSGLHMNRERKAAK	HRH1	401	P35367
FMANTYLRKDRHLGK	CCDC168	2531	Q8NDH2
LQSNGKDYMIRVKTH	FDXACB1	441	Q9BRP7
HSMYVTRDKVRAKGL	CDKL5	611	O76039
RTTLSSKMYHTKGQE	DKK1	171	O94907
NSGMRTKYRTKKGHV	SLC13A1	221	Q9BZW2
GKHKRVLIFASYMTT	CABLES2	316	Q9BTV7
EKSRHYGETKMNQRS	CENPE	186	Q02224
DNSHSMVGKLSRRIY	MAP3K1	806	Q13233
KSYDNVMHVGLRKVT	MAP3K4	1326	Q9Y6R4
GSLSFSRHKYKMLAD	C8orf17	41	Q9NRJ1
YSVKKRHFIGNTSMD	TRMT11	186	Q7Z4G4
LKSFQKMGYVRRDSH	SPATA2L	121	Q8IUW3
IAMVGKYFSRRKALA	SLC16A12	161	Q6ZSM3
RKHLTEKFYSMRSSR	PTAFR	301	P25105
SHFRDGMQALYKVKS	HEPH	351	Q9BQS7
SRKYSFKAVHTGMRA	PLEKHA7	226	Q6IQ23
MFKKVHGLYRTTGAS	SCAMP1	281	O15126
MGRKVKSQYLLTAIH	SFRP1	271	Q8N474
TTYGRIHMQKQDLSK	RPF2	261	Q9H7B2
MYTLHTKRVKAAARQ	CCDC54	1	Q8NEL0
MTNRKFRHDKRVYLG	PRPF8	76	Q6P2Q9
HIAQKAGRKTYAMVS	TUFT1	41	Q9NNX1
FKRYVFDTHKRMVQS	EEFSEC	581	P57772
SGMTLHERFTKYLKR	THRAP3	646	Q9Y2W1
NTYGKVFMHRRTSLK	ZNF555	146	Q8NEP9
GKAFSSKSYLIIHMR	ZNF268	786	Q14587
VLMNGRKHFVEKRYS	SNX24	26	Q9Y343
RAGRFHKNMIKSFYT	VTA1	106	Q9NP79
GVSQRKLMRYHSVST	TBC1D1	616	Q86TI0
TMIRIFHRYSGKERK	S100Z	11	Q8WXG8
KSRTNMAVKQGRFYL	POLR3B	211	Q9NW08
KSQMITYQRRHTGEK	ZNF630	611	Q2M218
RMNARRYKHFKVTTT	ZDHHC17	566	Q8IUH5
LVNHSRSYTKMKTFE	ZFP69B	266	Q9UJL9
KAFRSKSYLLVHIRM	ZNF26	321	P17031
RTSGRRKTHMQFHYK	ZNF236	1261	Q9UL36
QSTLKGLEYLHFMRK	STK4	131	Q13043
VKRYVAAMIRNSKTH	TRPC5	721	Q9UL62
TSEKMTTYKRHNFLT	ZFP14	146	Q9HCL3
IFREGMKNTSYVLKH	ZNF280C	161	Q8ND82
RKFNSYIHRKSAMIP	TECRL	346	Q5HYJ1
KNHSMKEIGSLLARY	WDR35	906	Q9P2L0
RKSYVRPGSLSTHMK	ZNF438	541	Q7Z4V0
FRKTGQSVYMHLKRH	USP13	81	Q92995
RISNLTLYKKSHMGE	ZNF891	331	A8MT65
GKTYRQTSTLAMHKR	ZNF76	351	P36508
HGVSRKKIAQMLDRY	N4BP2L2	521	Q92802