Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat kinase activity	CCNK BRD4	1.41e-04	10	36	2	GO:0008353
GeneOntologyMolecularFunction	chromatin binding	KMT2A ZNF609 TOX4 ERCC6 TAF5 AHDC1 BRD4	3.02e-04	739	36	7	GO:0003682
GeneOntologyMolecularFunction	transcription coregulator activity	SIAH2 TCF20 TAF6 ATF7IP BRD4 ARID5B	4.59e-04	562	36	6	GO:0003712
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat modifying activity	CCNK BRD4	7.81e-04	23	36	2	GO:0140994
GeneOntologyMolecularFunction	lysine-acetylated histone binding	KMT2A BRD4	1.33e-03	30	36	2	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	KMT2A BRD4	1.42e-03	31	36	2	GO:0140033
GeneOntologyMolecularFunction	transcription coactivator activity	TCF20 TAF6 BRD4 ARID5B	2.09e-03	303	36	4	GO:0003713
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	AKAP4 TAF5 TAF6 CCNK PIK3CD BRD4	1.49e-05	335	34	6	GO:0061695
GeneOntologyCellularComponent	cyclin/CDK positive transcription elongation factor complex	CCNK BRD4	9.18e-05	9	34	2	GO:0008024
GeneOntologyCellularComponent	transcription elongation factor complex	ERCC6 CCNK BRD4	1.03e-04	56	34	3	GO:0008023
GeneOntologyCellularComponent	transferase complex	KMT2A DEPDC5 AKAP4 TAF5 TAF6 CCNK PIK3CD BRD4	1.23e-04	963	34	8	GO:1990234
GeneOntologyCellularComponent	nuclear cyclin-dependent protein kinase holoenzyme complex	CCNK BRD4	3.87e-04	18	34	2	GO:0019908
GeneOntologyCellularComponent	transcription factor TFTC complex	TAF5 TAF6	3.87e-04	18	34	2	GO:0033276
GeneOntologyCellularComponent	carboxy-terminal domain protein kinase complex	CCNK BRD4	6.93e-04	24	34	2	GO:0032806
GeneOntologyCellularComponent	MLL1 complex	KMT2A TAF6	1.24e-03	32	34	2	GO:0071339
GeneOntologyCellularComponent	MLL1/2 complex	KMT2A TAF6	1.31e-03	33	34	2	GO:0044665
GeneOntologyCellularComponent	SAGA-type complex	TAF5 TAF6	1.83e-03	39	34	2	GO:0070461
GeneOntologyCellularComponent	serine/threonine protein kinase complex	AKAP4 CCNK BRD4	2.10e-03	157	34	3	GO:1902554
GeneOntologyCellularComponent	protein kinase complex	AKAP4 CCNK BRD4	2.63e-03	170	34	3	GO:1902911
GeneOntologyCellularComponent	transcription factor TFIID complex	TAF5 TAF6	2.65e-03	47	34	2	GO:0005669
GeneOntologyCellularComponent	cyclin-dependent protein kinase holoenzyme complex	CCNK BRD4	4.42e-03	61	34	2	GO:0000307
GeneOntologyCellularComponent	nuclear protein-containing complex	KMT2A CPSF4 ERCC6 TAF5 TAF6 CCNK BRD4	5.92e-03	1377	34	7	GO:0140513
GeneOntologyCellularComponent	histone methyltransferase complex	KMT2A TAF6	6.62e-03	75	34	2	GO:0035097
HumanPheno	Thin vermilion border	KMT2A PACS1 ERCC6 TCF20 TAF6 CCNK PIK3CD BRD4	4.86e-06	433	14	8	HP:0000233
HumanPheno	Long eyelashes	KMT2A PACS1 DEPDC5 TAF6 BRD4	1.61e-05	129	14	5	HP:0000527
HumanPheno	Diagnostic behavioral phenotype	SYN2 KMT2A PACS1 DEPDC5 SLITRK2 TCF20 CCNK AHDC1 BRD4	3.00e-05	747	14	9	HP:0025783
HumanPheno	Abnormality of the hairline	KMT2A PACS1 TAF6 CCNK PIK3CD BRD4	7.11e-05	294	14	6	HP:0009553
HumanPheno	Congenital abnormal hair pattern	KMT2A PACS1 TAF6 CCNK PIK3CD BRD4	1.29e-04	327	14	6	HP:0011361
HumanPheno	Autistic behavior	KMT2A PACS1 DEPDC5 SLITRK2 TCF20 CCNK AHDC1 BRD4	1.36e-04	678	14	8	HP:0000729
Domain	EPHD	KMT2A TCF20	8.14e-04	22	36	2	PS51805
Domain	AT_hook	KMT2A AHDC1	1.23e-03	27	36	2	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2A AHDC1	1.23e-03	27	36	2	IPR017956
Domain	Znf_FYVE_PHD	KMT2A TCF20 MOBP	2.82e-03	147	36	3	IPR011011
Domain	BROMODOMAIN_2	KMT2A BRD4	2.83e-03	41	36	2	PS50014
Domain	BROMO	KMT2A BRD4	2.96e-03	42	36	2	SM00297
Domain	Bromodomain	KMT2A BRD4	2.96e-03	42	36	2	IPR001487
Domain	-	KMT2A BRD4	2.96e-03	42	36	2	1.20.920.10
Domain	PHD	KMT2A TCF20	1.27e-02	89	36	2	SM00249
Domain	Znf_PHD	KMT2A TCF20	1.33e-02	91	36	2	IPR001965
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	KMT2A CPSF4 ZNF609 TCF20 CCNK AHDC1 BRD4 ARID5B	2.81e-10	268	36	8	33640491
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2A TOX4 TAF5 TCF20 TAF6 CCNK BRD4 SEC16A	7.52e-08	549	36	8	38280479
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	CPSF4 ZNF609 TOX4 TCF20 TAF6 BRD4 KCMF1 NOBOX ARID5B	1.01e-07	808	36	9	20412781
Pubmed	Human transcription factor protein interaction networks.	KMT2A LARP4B CPSF4 ZNF609 TAF5 TCF20 TAF6 ATF7IP KCMF1 ARID5B SEC16A	1.26e-07	1429	36	11	35140242
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF609 TOX4 TCF20 ATF7IP BRD4 ARID5B SEC16A	2.13e-07	418	36	7	34709266
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	KMT2A ZNF609 TOX4 TCF20 TAF6 CCNK ATF7IP BRD4 SEC16A	4.10e-07	954	36	9	36373674
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	KMT2A CPSF4 ZNF609 TOX4 TAF5 TCF20 TAF6 AHDC1 BRD4 ARID5B	5.16e-07	1294	36	10	30804502
Pubmed	Interaction network of human early embryonic transcription factors.	KMT2A ZNF609 TCF20 AHDC1 ARID5B SEC16A	1.53e-06	351	36	6	38297188
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	ZNF609 ARID5B SEC16A	2.03e-06	24	36	3	33722704
Pubmed	TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein.	TAF5 TAF6	3.12e-06	3	36	2	22696218
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	ZNF609 TCF20 ATF7IP BRD4 ARID5B SEC16A	3.15e-06	398	36	6	35016035
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	KMT2A TCF20 TAF6 BRD4	3.97e-06	103	36	4	32744500
Pubmed	Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology?	KMT2A SIAH2	6.24e-06	4	36	2	15221006
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KMT2A LARP4B CPSF4 CCNK AHDC1 BRD4	8.05e-06	469	36	6	27634302
Pubmed	CTGC motifs within the HIV core promoter specify Tat-responsive pre-initiation complexes.	TAF5 TAF6	1.04e-05	5	36	2	22834489
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	KMT2A TCF20 CCNK BRD4	1.13e-05	134	36	4	25452129
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2A PACS1 TCF20 TAF6 CCNK BRD4 SEC16A	1.25e-05	774	36	7	15302935
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	AMBN LARP4B ZNF609 ERCC6 TAF5 TAF6 BRD4 SEC16A	1.49e-05	1116	36	8	31753913
Pubmed	Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation.	TAF5 TAF6	1.56e-05	6	36	2	7680771
Pubmed	Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130.	TAF5 TAF6	1.56e-05	6	36	2	8858156
Pubmed	Abnormal sperm in mice lacking the Taf7l gene.	TAF5 TAF6	1.56e-05	6	36	2	17242199
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KMT2A LARP4B CPSF4 ERCC6 TAF5 TAF6 CAMSAP2 CCNK AHDC1	1.62e-05	1497	36	9	31527615
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	KMT2A CPSF4 TOX4 CCNK BRD4	2.51e-05	339	36	5	30415952
Pubmed	Specific interactions and potential functions of human TAFII100.	TAF5 TAF6	2.91e-05	8	36	2	9045704
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	SIAH2 ZNF609 TOX4 CAMSAP2 CCNK AHDC1	3.47e-05	608	36	6	16713569
Pubmed	TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.	TAF5 TAF6	3.73e-05	9	36	2	15899866
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	KMT2A TOX4 TAF6 CAMSAP2 CCNK ATF7IP SEC16A	4.16e-05	934	36	7	33916271
Pubmed	The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners.	TAF5 TAF6	4.66e-05	10	36	2	15870280
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	KMT2A DEPDC5 ZNF609 TAF6 BRD4 KCMF1 ARID5B SEC16A	5.13e-05	1327	36	8	32694731
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	KMT2A TAF5 TCF20 TAF6 BRD4	5.14e-05	394	36	5	27248496
Pubmed	CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues.	TAF5 TAF6	5.70e-05	11	36	2	9153318
Pubmed	Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.	ERCC6 TAF5 TAF6	6.80e-05	76	36	3	22323595
Pubmed	The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity.	TAF5 TAF6	6.83e-05	12	36	2	10523658
Pubmed	A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes.	TAF5 TAF6	8.07e-05	13	36	2	20953165
Pubmed	SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors.	TAF5 TAF6	8.07e-05	13	36	2	23884650
Pubmed	Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA.	TAF5 TAF6	8.07e-05	13	36	2	9311784
Pubmed	Identification of a small TAF complex and its role in the assembly of TAF-containing complexes.	TAF5 TAF6	9.41e-05	14	36	2	17375202
Pubmed	Structure of promoter-bound TFIID and model of human pre-initiation complex assembly.	TAF5 TAF6	9.41e-05	14	36	2	27007846
Pubmed	Human TFIID binds to core promoter DNA in a reorganized structural state.	TAF5 TAF6	9.41e-05	14	36	2	23332750
Pubmed	Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action.	PACS1 PIK3CD	1.08e-04	15	36	2	20702582
Pubmed	The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.	TAF5 TAF6	1.08e-04	15	36	2	14580349
Pubmed	Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis.	TAF5 TAF6	1.08e-04	15	36	2	12601814
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	KMT2A ZNF609 TCF20 TAF6 CCNK AHDC1 BRD4	1.18e-04	1103	36	7	34189442
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	THAP8 SIAH2 DEPDC5 AHDC1 PIK3CD BRD4 SEC16A	1.19e-04	1105	36	7	35748872
Pubmed	Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro.	TAF5 TAF6	1.24e-04	16	36	2	8680883
Pubmed	Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly.	TAF5 TAF6	1.24e-04	16	36	2	8764009
Pubmed	Direct interaction of human TFIID with the HIV-1 transactivator tat.	TAF5 TAF6	1.24e-04	16	36	2	8121496
Pubmed	A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro.	TAF5 TAF6	1.24e-04	16	36	2	7836461
Pubmed	Novel mechanism and factor for regulation by HIV-1 Tat.	TAF5 TAF6	1.24e-04	16	36	2	7835343
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	KMT2A CPSF4 TOX4 CCNK	1.30e-04	251	36	4	31076518
Pubmed	Histone-like TAFs within the PCAF histone acetylase complex.	TAF5 TAF6	1.40e-04	17	36	2	9674425
Pubmed	The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.	KMT2A BRD4	1.58e-04	18	36	2	21030982
Pubmed	HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway.	PACS1 PIK3CD	1.58e-04	18	36	2	12526811
Pubmed	Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.	TAF5 TAF6	1.58e-04	18	36	2	29111974
Pubmed	Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.	TAF5 TAF6	1.58e-04	18	36	2	15053879
Pubmed	Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.	TAF5 TAF6	1.58e-04	18	36	2	7933101
Pubmed	Functional genomics identifies therapeutic targets for MYC-driven cancer.	PAK6 CCNK BRD4	1.68e-04	103	36	3	22623531
Pubmed	Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex.	TAF5 TAF6	1.76e-04	19	36	2	8764062
Pubmed	UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.	TAF5 TAF6	1.96e-04	20	36	2	11406595
Pubmed	Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II.	TAF5 TAF6	1.96e-04	20	36	2	9603525
Pubmed	Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.	TAF5 TAF6	1.96e-04	20	36	2	17884155
Pubmed	Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.	TAF5 TAF6	1.96e-04	20	36	2	10373431
Pubmed	STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.	TAF5 TAF6	1.96e-04	20	36	2	17967894
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	KMT2A LARP4B ERCC6 CCNK	2.00e-04	281	36	4	24163370
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	ZNF609 KCMF1 ARID5B SEC16A	2.03e-04	282	36	4	23667531
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	TOX4 TCF20 CCNK BRD4	2.06e-04	283	36	4	30585729
Pubmed	ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.	KMT2A TAF6	2.16e-04	21	36	2	12453419
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KMT2A PAK6 TCF20 CAMSAP2 BRD4 SEC16A	2.34e-04	861	36	6	36931259
Pubmed	Selective recognition of viral promoters by host cell transcription complexes: challenges and opportunities to control latency.	TAF5 TAF6	2.83e-04	24	36	2	23827503
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	TAF5 TAF6 AHDC1	2.90e-04	124	36	3	20850016
Pubmed	The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.	TAF5 TAF6	3.08e-04	25	36	2	19240132
Pubmed	Functional proteomics mapping of a human signaling pathway.	SIAH2 TOX4 ERCC6 ATF7IP BRD4	3.40e-04	591	36	5	15231748
Pubmed	Identification of 14-3-3epsilon substrates from embryonic murine brain.	SYN2 PACS1 GAB4	3.48e-04	132	36	3	16944949
Pubmed	Rebalancing gene haploinsufficiency in vivo by targeting chromatin.	KMT2A PIK3CD	3.87e-04	28	36	2	27256596
Pubmed	The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.	TAF5 TAF6	3.87e-04	28	36	2	19114550
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NYAP2 TAF5 TCF20 CAMSAP2 ATF7IP SEC16A	4.25e-04	963	36	6	28671696
Pubmed	Cerebellar development transcriptome database (CDT-DB): profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum.	MOBP KCMF1	4.45e-04	30	36	2	18603407
Pubmed	A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.	TAF5 TAF6	4.45e-04	30	36	2	18206972
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	ZNF609 ARID5B SEC16A	4.67e-04	146	36	3	23892456
Pubmed	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.	KMT2A TAF6	4.75e-04	31	36	2	15960975
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	SYN2 PACS1 CAMSAP2	4.77e-04	147	36	3	16959763
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	TCF20 GAB4 ARID5B	5.26e-04	152	36	3	34299191
Pubmed	Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.	TAF5 TAF6	5.39e-04	33	36	2	11564863
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KMT2A BRD4	5.39e-04	33	36	2	26864203
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	KMT2A ERCC6 AHDC1	5.78e-04	157	36	3	30686591
Pubmed	Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes.	TAF5 TAF6	7.54e-04	39	36	2	9054383
Pubmed	The general transcription factors of RNA polymerase II.	TAF5 TAF6	7.54e-04	39	36	2	8946909
Pubmed	Three transitions in the RNA polymerase II transcription complex during initiation.	TAF5 TAF6	7.54e-04	39	36	2	9405375
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	KMT2A CPSF4 TOX4 TCF20 BRD4	7.75e-04	709	36	5	22988430
Pubmed	Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter.	TAF5 TAF6	7.93e-04	40	36	2	1939271
Pubmed	ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis.	TAF5 TAF6	7.93e-04	40	36	2	2449431
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	ZNF609 TCF20 SEC16A	8.58e-04	180	36	3	35198878
Pubmed	Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.	TAF5 TAF6	9.16e-04	43	36	2	18722179
Interaction	AR interactions	KMT2A SIAH2 CPSF4 ZNF609 PAK6 TCF20 CCNK AHDC1 BRD4 ARID5B SEC16A	7.51e-07	992	36	11	int:AR
Interaction	ALG13 interactions	LARP4B ZNF609 TCF20 CCNK SEC16A	1.75e-05	183	36	5	int:ALG13
Interaction	PHIP interactions	LARP4B ZNF609 TAF5 TAF6 BRD4	2.50e-05	197	36	5	int:PHIP
Interaction	PML interactions	KMT2A SIAH2 ZNF609 ERCC6 TAF6 AHDC1 ATF7IP BRD4 SEC16A	2.86e-05	933	36	9	int:PML
Interaction	FEV interactions	KMT2A ZNF609 TAF5 TCF20 TAF6	2.89e-05	203	36	5	int:FEV
Interaction	TLE3 interactions	KMT2A ZNF609 TCF20 AHDC1 BRD4 ARID5B	4.92e-05	376	36	6	int:TLE3
Interaction	SMC5 interactions	KMT2A ZNF609 TOX4 TCF20 TAF6 CCNK ATF7IP BRD4 SEC16A	4.92e-05	1000	36	9	int:SMC5
Interaction	CTR9 interactions	KMT2A DEPDC5 TOX4 ERCC6 BRD4	5.57e-05	233	36	5	int:CTR9
Interaction	CPSF1 interactions	CPSF4 TAF5 TCF20 BRD4 KCMF1	8.53e-05	255	36	5	int:CPSF1
Interaction	HDAC2 interactions	KMT2A LARP4B ZNF609 ERCC6 TCF20 TAF6 BRD4 ARID5B	1.16e-04	865	36	8	int:HDAC2
Interaction	YY1 interactions	KMT2A TOX4 TAF5 TAF6 ATF7IP BRD4	1.39e-04	454	36	6	int:YY1
Interaction	TAF9 interactions	KMT2A TAF5 TAF6 BRD4	1.81e-04	159	36	4	int:TAF9
Interaction	SOX5 interactions	ZNF609 TCF20 TAF6 ATF7IP	1.94e-04	162	36	4	int:SOX5
Coexpression	NAKAYA_MYELOID_DENDRITIC_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN	ZNF609 TOX4 TCF20 TAF6 ATF7IP	3.19e-05	269	36	5	M41203
Coexpression	GSE37532_WT_VS_PPARG_KO_LN_TREG_UP	TAF6 CCNK BRD4 ARID5B	9.78e-05	176	36	4	M8952
Coexpression	GSE11057_CD4_CENT_MEM_VS_PBMC_UP	KMT2A PACS1 TCF20 ARID5B	1.54e-04	198	36	4	M3116
Coexpression	GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP	CAMSAP2 PIK3CD KCMF1 SEC16A	1.54e-04	198	36	4	M9571
Coexpression	GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN	PACS1 PIK3CD ARID5B SEC16A	1.57e-04	199	36	4	M9443
Coexpression	GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN	CARD6 TCF20 CAMSAP2 ATF7IP	1.57e-04	199	36	4	M9253
Coexpression	GSE20715_WT_VS_TLR4_KO_LUNG_DN	KMT2A CPSF4 BRD4 SEC16A	1.57e-04	199	36	4	M4350
Coexpression	GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN	KMT2A TAF5 TCF20 PIK3CD	1.60e-04	200	36	4	M5851
Coexpression	GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_DN	SYN2 LARP4B ZNF474 KCMF1	1.60e-04	200	36	4	M4039
Drug	Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; PC3; HT_HG-U133A	KMT2A AKAP4 ADAM12 CCNK PIK3CD	1.21e-05	197	35	5	4475_UP
Drug	PF-01378883-00 [351320-41-7]; Up 200; 10uM; PC3; HT_HG-U133A	SYN2 PACS1 ADAM12 CCNK MOBP	1.27e-05	199	35	5	6410_UP
Disease	Cornelia De Lange Syndrome	KMT2A BRD4	3.81e-05	8	35	2	C0270972
Disease	leptin measurement, type 2 diabetes mellitus	SYN2 NYAP2	1.62e-04	16	35	2	EFO_0005000, MONDO_0005148
Disease	necrotizing enterocolitis	SYN2 TCF20	4.71e-04	27	35	2	EFO_0003928
Disease	body mass index, fasting blood insulin measurement	SYN2 NYAP2	7.05e-04	33	35	2	EFO_0004340, EFO_0004466
Disease	disease recurrence, unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement	PAK6 ADAM12	7.05e-04	33	35	2	EFO_0003761, EFO_0004952, EFO_0008343, MONDO_0004985, MONDO_0005090
Disease	spleen volume	SYN2 NYAP2	1.20e-03	43	35	2	EFO_0600047
Disease	non-alcoholic fatty liver disease	SYN2 TOX4 NYAP2	1.31e-03	182	35	3	EFO_0003095
Disease	reticulocyte measurement	SYN2 PACS1 DEPDC5 LARP4B NYAP2 BRD4	1.36e-03	1053	35	6	EFO_0010700
Disease	response to hydrochlorothiazide, fasting blood glucose measurement	ZNF474 ADAM12	1.37e-03	46	35	2	EFO_0004465, EFO_0005202
Disease	depressive symptom measurement	SYN2 KMT2A NYAP2 TCF20	1.57e-03	426	35	4	EFO_0007006
Disease	L2 Acute Lymphoblastic Leukemia	KMT2A ARID5B	1.62e-03	50	35	2	C0023453
Disease	Childhood Acute Lymphoblastic Leukemia	KMT2A ARID5B	1.75e-03	52	35	2	C0023452
Disease	visceral:abdominal adipose tissue ratio measurement	NYAP2 ARID5B	1.75e-03	52	35	2	EFO_0803318
Disease	Intellectual Disability	PACS1 TCF20 TAF6 BRD4	1.88e-03	447	35	4	C3714756
Disease	Small cell carcinoma of lung	KMT2A PAK6	1.88e-03	54	35	2	C0149925
Disease	total blood protein measurement	ZNF609 NYAP2 ARID5B SEC16A	1.91e-03	449	35	4	EFO_0004536
Disease	corneal resistance factor	KMT2A ZNF474 ATF7IP ARID5B	1.94e-03	451	35	4	EFO_0010067
Disease	cholesterol to total lipids in large HDL percentage	SYN2 NYAP2	1.95e-03	55	35	2	EFO_0022234
Disease	free cholesterol to total lipids in very large HDL percentage	SYN2 NYAP2	1.95e-03	55	35	2	EFO_0022288
Disease	prostate carcinoma, type 2 diabetes mellitus	SYN2 NYAP2	2.24e-03	59	35	2	EFO_0001663, MONDO_0005148
Disease	cholesteryl esters to total lipids in large HDL percentage	SYN2 NYAP2	2.24e-03	59	35	2	EFO_0022248

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPPETSNPNKPKRQT	BRD4	46	O60885
NNNQSPSAPPAKPPS	AKAP4	186	Q5JQC9
PSQPSLKPQQPGLKP	AMBN	111	Q9NP70
PAQQPKKPSPQPSSP	CCNK	316	O75909
QGTCKPNPPQKPLPA	ADAM12	846	O43184
IPKPQPVNPLFQDSP	AHDC1	1296	Q5TGY3
PVTPPAPVQNKNKPN	ERCC6	301	Q03468
QAPQPPLFQSPQPKL	NOBOX	521	O60393
PVTPPAPVQNKNKPN	ERCC6	301	P0DP91
QPKTQKPNPAVPPPL	DEPDC5	816	O75140
KPNSSFRPPQKDNPP	PAK6	286	Q9NQU5
PPSSPLQPQKEQKPN	LARP4B	661	Q92615
PPPKPKRNPNTQLST	NYAP2	191	Q9P242
PPQQPTPPKLAQATS	PACS1	41	Q6VY07
QSKPSQPRPPQPKSS	CARD6	1001	Q9BX69
NRSLKPNQKANPTPP	GAB4	421	Q2WGN9
NPVSLPSLPNPTKPN	ATF7IP	831	Q6VMQ6
PSLPNPTKPNNVPSV	ATF7IP	836	Q6VMQ6
NLKESNKGNEPPPPP	KCMF1	366	Q9P0J7
QPPPPESGPEQSKQK	KMT2A	1331	Q03164
TEQPPLPQQTQPPAK	CPSF4	176	O95639
QEPPPPTLEPQKAQK	B3GNT7	36	Q8NFL0
PNEDQLNQPTEPPPK	CAMSAP2	1096	Q08AD1
KQDPNAPPQNRIPLP	TAF5	416	Q15542
PENPPPAPKEQQKAE	TAF6	146	P49848
APPQKPQPHPQLNKS	SYN2	526	Q92777
QKPVSPPPPLQKNTP	THAP8	101	Q8NA92
LNKFEPKLPPQNNPV	OVCH1	536	Q7RTY7
KPNHPLLQAKPQSEP	SLITRK2	816	Q9H156
ANKPCSKQPPPQPQH	SIAH2	11	O43255
PPAKQRPPQKSKQQP	MOBP	146	Q13875
PLPPIKPRKQENSSQ	ARID5B	416	Q14865
LVPPQQQASPPQLPK	SEC16A	1061	O15027
PNSPQLKPIQPKPTV	ZNF609	696	O15014
NPAPQVQKPRAKPPP	PIK3CD	291	O00329
SVNKQKKQQQPPPPP	TCF20	1546	Q9UGU0
PLPQKPQPLPNAQSS	ZNF474	261	Q6S9Z5
QQPPPLQIKSVPLPT	TOX4	486	O94842