| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | GTPase activator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 TBC1D22B DEPDC1 TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 7.97e-09 | 279 | 137 | 14 | GO:0005096 |
| GeneOntologyMolecularFunction | histone phosphatase activity | 3.16e-07 | 3 | 137 | 3 | GO:0140789 | |
| GeneOntologyMolecularFunction | histone H2AXY142 phosphatase activity | 3.16e-07 | 3 | 137 | 3 | GO:0140793 | |
| GeneOntologyMolecularFunction | nucleoside-triphosphatase regulator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 TBC1D22B DEPDC1 TBC1D3C DENND2B TBC1D3B ARHGEF7 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 4.14e-07 | 507 | 137 | 16 | GO:0060589 |
| GeneOntologyMolecularFunction | GTPase regulator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 TBC1D22B DEPDC1 TBC1D3C DENND2B TBC1D3B ARHGEF7 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 4.14e-07 | 507 | 137 | 16 | GO:0030695 |
| GeneOntologyMolecularFunction | enzyme activator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 PARP8 TBC1D22B DEPDC1 TBC1D3C TBC1D3B GTF3C4 VAC14 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 2.65e-06 | 656 | 137 | 17 | GO:0008047 |
| GeneOntologyMolecularFunction | calmodulin binding | 3.05e-05 | 230 | 137 | 9 | GO:0005516 | |
| GeneOntologyMolecularFunction | enzyme regulator activity | CCNI2 TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 PARP8 TBC1D22B DEPDC1 TBC1D3C DENND2B TBC1D3B GTF3C4 PRKAG3 CCNF VAC14 CCNB3 ARHGEF7 TBC1D3I TBC1D3G ATP2B4 TBC1D3K TBC1D3F | 3.33e-05 | 1418 | 137 | 24 | GO:0030234 |
| GeneOntologyMolecularFunction | P-type calcium transporter activity | 5.01e-05 | 11 | 137 | 3 | GO:0005388 | |
| GeneOntologyMolecularFunction | actin filament binding | 1.75e-04 | 227 | 137 | 8 | GO:0051015 | |
| GeneOntologyMolecularFunction | histone modifying activity | 1.86e-04 | 229 | 137 | 8 | GO:0140993 | |
| GeneOntologyMolecularFunction | nuclear receptor binding | 3.12e-04 | 187 | 137 | 7 | GO:0016922 | |
| GeneOntologyMolecularFunction | actin binding | MYO1D IQGAP2 SPTAN1 SPTBN1 FERMT1 ACTN4 CORO1B ACTN3 DMD SETD3 UTRN | 4.74e-04 | 479 | 137 | 11 | GO:0003779 |
| GeneOntologyMolecularFunction | nuclear retinoic acid receptor binding | 5.51e-04 | 55 | 137 | 4 | GO:0042974 | |
| GeneOntologyMolecularFunction | histone H3K4me/H3K4me2/H3K4me3 demethylase activity | 6.88e-04 | 6 | 137 | 2 | GO:0034647 | |
| GeneOntologyMolecularFunction | histone H3K4 demethylase activity | 1.27e-03 | 8 | 137 | 2 | GO:0032453 | |
| GeneOntologyMolecularFunction | PDZ domain binding | 1.60e-03 | 123 | 137 | 5 | GO:0030165 | |
| GeneOntologyMolecularFunction | low-density lipoprotein particle receptor binding | 1.62e-03 | 34 | 137 | 3 | GO:0050750 | |
| GeneOntologyMolecularFunction | P-type transmembrane transporter activity | 1.91e-03 | 36 | 137 | 3 | GO:0140358 | |
| GeneOntologyMolecularFunction | P-type ion transporter activity | 1.91e-03 | 36 | 137 | 3 | GO:0015662 | |
| GeneOntologyMolecularFunction | molecular function activator activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 PARP8 TBC1D22B DEPDC1 TBC1D3C TBC1D3B GTF3C4 VAC14 TBC1D3I PDGFC TBC1D3G TBC1D3K TBC1D3F | 1.94e-03 | 1233 | 137 | 18 | GO:0140677 |
| GeneOntologyMolecularFunction | RNA polymerase II-specific DNA-binding transcription factor binding | 2.37e-03 | 417 | 137 | 9 | GO:0061629 | |
| GeneOntologyMolecularFunction | lipoprotein particle receptor binding | 2.41e-03 | 39 | 137 | 3 | GO:0070325 | |
| GeneOntologyMolecularFunction | ubiquitin-like ligase-substrate adaptor activity | 2.45e-03 | 82 | 137 | 4 | GO:1990756 | |
| GeneOntologyBiologicalProcess | activation of GTPase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D22B TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 8.19e-12 | 109 | 137 | 12 | GO:0090630 |
| GeneOntologyBiologicalProcess | regulation of GTPase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 TBC1D22B TBC1D3C TBC1D3B PROM2 ARHGEF7 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 6.86e-09 | 335 | 137 | 15 | GO:0043087 |
| GeneOntologyBiologicalProcess | positive regulation of GTPase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D22B TBC1D3C TBC1D3B ARHGEF7 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 9.42e-09 | 244 | 137 | 13 | GO:0043547 |
| GeneOntologyBiologicalProcess | positive regulation of hydrolase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D GPER1 TBC1D22B TBC1D3C TBC1D3B ARHGEF7 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 6.13e-06 | 499 | 137 | 14 | GO:0051345 |
| GeneOntologyBiologicalProcess | regulation of hydrolase activity | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 GPER1 TBC1D22B TBC1D3C TBC1D3B PROM2 ARHGEF7 TBC1D3I TBC1D3G HTT TBC1D3K TBC1D3F | 7.39e-05 | 878 | 137 | 17 | GO:0051336 |
| GeneOntologyCellularComponent | axon | MYO1D GPER1 USP9X POLG SPTAN1 SPTBN1 CRMP1 CPNE6 SACS ARHGEF7 LRP2 SLC17A8 MME DMD CHRNA10 ATP2B3 HTT | 8.24e-05 | 891 | 138 | 17 | GO:0030424 |
| GeneOntologyCellularComponent | cell projection membrane | MYO1D GPER1 SPTBN1 FERMT1 PTPRH PROM2 LRP2 PLCG2 DMD ATP2B1 UTRN | 1.39e-04 | 431 | 138 | 11 | GO:0031253 |
| GeneOntologyCellularComponent | endosome | TBC1D3 MYO1D GPER1 SLC30A4 DENND2B EHD4 USP6 VAC14 CPNE6 AP2A1 AP2A2 VPS35L LRP2 SLC17A8 DIO3 MME BAIAP3 HTT MITD1 | 2.44e-04 | 1167 | 138 | 19 | GO:0005768 |
| GeneOntologyCellularComponent | cytoplasmic vesicle membrane | MOXD2P TBC1D3 IQGAP2 GPER1 SLC30A4 EHD4 VAC14 AP2A1 AP2A2 OTOF VPS35L LRP2 SLC17A8 DIO3 MME DMD BAIAP3 ATP2B1 HTT MITD1 | 3.71e-04 | 1307 | 138 | 20 | GO:0030659 |
| GeneOntologyCellularComponent | vesicle membrane | MOXD2P TBC1D3 IQGAP2 GPER1 SLC30A4 EHD4 VAC14 AP2A1 AP2A2 OTOF VPS35L LRP2 SLC17A8 DIO3 MME DMD BAIAP3 ATP2B1 HTT MITD1 | 4.42e-04 | 1325 | 138 | 20 | GO:0012506 |
| MousePheno | abnormal ear physiology | PRAMEF5 MYO1D IQGAP2 POLG DEPDC1 EYA1 EYA2 DPP8 SLC30A4 WARS2 OTOF PRAMEF14 LRP2 SLC17A8 DMD CHRNA10 ATP2B1 PRAMEF6 OTOG | 4.31e-07 | 684 | 102 | 19 | MP:0003878 |
| MousePheno | hearing/vestibular/ear phenotype | PRAMEF5 MYO1D IQGAP2 POLG SPTBN1 ACTN4 DEPDC1 EYA1 EYA2 DPP8 SLC30A4 WARS2 OTOF PRAMEF14 LRP2 SLC17A8 DMD CHRNA10 ATP2B1 PRAMEF6 HTT OTOG | 4.53e-07 | 905 | 102 | 22 | MP:0005377 |
| MousePheno | abnormal hearing physiology | PRAMEF5 MYO1D IQGAP2 POLG DEPDC1 EYA1 EYA2 DPP8 WARS2 OTOF PRAMEF14 LRP2 SLC17A8 DMD CHRNA10 ATP2B1 PRAMEF6 OTOG | 8.12e-07 | 643 | 102 | 18 | MP:0001963 |
| MousePheno | abnormal auditory brainstem response | PRAMEF5 MYO1D IQGAP2 POLG DEPDC1 EYA1 EYA2 DPP8 OTOF PRAMEF14 LRP2 SLC17A8 DMD ATP2B1 PRAMEF6 OTOG | 3.96e-06 | 576 | 102 | 16 | MP:0004738 |
| MousePheno | abnormal hearing electrophysiology | PRAMEF5 MYO1D IQGAP2 POLG DEPDC1 EYA1 EYA2 DPP8 OTOF PRAMEF14 LRP2 SLC17A8 DMD ATP2B1 PRAMEF6 OTOG | 5.86e-06 | 594 | 102 | 16 | MP:0006335 |
| Domain | TBC | TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D22B TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 1.09e-15 | 49 | 137 | 12 | SM00164 |
| Domain | RabGAP-TBC | TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D22B TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 3.07e-15 | 53 | 137 | 12 | PF00566 |
| Domain | Rab-GTPase-TBC_dom | TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D22B TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 4.98e-15 | 55 | 137 | 12 | IPR000195 |
| Domain | TBC_RABGAP | TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D22B TBC1D3C TBC1D3B USP6 TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 4.98e-15 | 55 | 137 | 12 | PS50086 |
| Domain | Spectrin | 1.27e-08 | 23 | 137 | 6 | PF00435 | |
| Domain | Spectrin_repeat | 5.77e-08 | 29 | 137 | 6 | IPR002017 | |
| Domain | SPEC | 1.08e-07 | 32 | 137 | 6 | SM00150 | |
| Domain | Spectrin/alpha-actinin | 1.08e-07 | 32 | 137 | 6 | IPR018159 | |
| Domain | CH | 4.78e-07 | 65 | 137 | 7 | SM00033 | |
| Domain | ACTININ_2 | 5.97e-07 | 23 | 137 | 5 | PS00020 | |
| Domain | ACTININ_1 | 5.97e-07 | 23 | 137 | 5 | PS00019 | |
| Domain | Actinin_actin-bd_CS | 5.97e-07 | 23 | 137 | 5 | IPR001589 | |
| Domain | CH | 7.99e-07 | 70 | 137 | 7 | PF00307 | |
| Domain | - | 8.81e-07 | 71 | 137 | 7 | 1.10.418.10 | |
| Domain | CH | 1.07e-06 | 73 | 137 | 7 | PS50021 | |
| Domain | CH-domain | 1.28e-06 | 75 | 137 | 7 | IPR001715 | |
| Domain | ATP_Ca_trans_C | 1.54e-06 | 4 | 137 | 3 | IPR022141 | |
| Domain | ATP_Ca_trans_C | 1.54e-06 | 4 | 137 | 3 | PF12424 | |
| Domain | EYA_dom | 1.54e-06 | 4 | 137 | 3 | IPR006545 | |
| Domain | EYA_fam | 1.54e-06 | 4 | 137 | 3 | IPR028472 | |
| Domain | P-type_ATPase_IIB | 1.54e-06 | 4 | 137 | 3 | IPR006408 | |
| Domain | NPIP | 2.62e-06 | 14 | 137 | 4 | IPR009443 | |
| Domain | EFhand_Ca_insen | 7.60e-06 | 6 | 137 | 3 | PF08726 | |
| Domain | EF-hand_Ca_insen | 7.60e-06 | 6 | 137 | 3 | IPR014837 | |
| Domain | - | 5.34e-05 | 2 | 137 | 2 | 2.60.40.1030 | |
| Domain | Dystrophin | 5.34e-05 | 2 | 137 | 2 | IPR016344 | |
| Domain | Clathrin_a-adaptin_app_Ig-like | 5.34e-05 | 2 | 137 | 2 | IPR013038 | |
| Domain | GREB1 | 5.34e-05 | 2 | 137 | 2 | PF15782 | |
| Domain | ATP2B1/4 | 5.34e-05 | 2 | 137 | 2 | IPR030319 | |
| Domain | AP2_complex_asu | 5.34e-05 | 2 | 137 | 2 | IPR017104 | |
| Domain | Clathrin_a-adaptin_app_sub_C | 5.34e-05 | 2 | 137 | 2 | IPR003164 | |
| Domain | GREB1 | 5.34e-05 | 2 | 137 | 2 | IPR028422 | |
| Domain | Alpha_adaptin_C | 5.34e-05 | 2 | 137 | 2 | PF02296 | |
| Domain | ATPase_P-typ_TM_dom | 2.02e-04 | 16 | 137 | 3 | IPR023298 | |
| Domain | - | 2.02e-04 | 16 | 137 | 3 | 1.20.1110.10 | |
| Domain | ATPase_P-typ_cation-transptr_C | 2.44e-04 | 17 | 137 | 3 | IPR006068 | |
| Domain | Cation_ATPase_C | 2.44e-04 | 17 | 137 | 3 | PF00689 | |
| Domain | EF-hand-dom_pair | 2.72e-04 | 287 | 137 | 9 | IPR011992 | |
| Domain | Cation_ATPase_N | 2.91e-04 | 18 | 137 | 3 | PF00690 | |
| Domain | Cation_ATPase_N | 2.91e-04 | 18 | 137 | 3 | SM00831 | |
| Domain | Lys_sp_deMease-like_dom | 3.17e-04 | 4 | 137 | 2 | IPR013637 | |
| Domain | DDT | 3.17e-04 | 4 | 137 | 2 | PF02791 | |
| Domain | Clathrin_a/coatomer_app_sub_C | 3.17e-04 | 4 | 137 | 2 | IPR015873 | |
| Domain | PLU-1 | 3.17e-04 | 4 | 137 | 2 | PF08429 | |
| Domain | - | 3.17e-04 | 4 | 137 | 2 | 3.30.310.30 | |
| Domain | ATPase_P-typ_cation-transptr_N | 3.43e-04 | 19 | 137 | 3 | IPR004014 | |
| Domain | C2 | 4.12e-04 | 131 | 137 | 6 | PF00168 | |
| Domain | C2 | 5.23e-04 | 137 | 137 | 6 | SM00239 | |
| Domain | FerI | 5.26e-04 | 5 | 137 | 2 | SM01202 | |
| Domain | FerB | 5.26e-04 | 5 | 137 | 2 | SM01201 | |
| Domain | Ferlin_B-domain | 5.26e-04 | 5 | 137 | 2 | IPR012561 | |
| Domain | DDT | 5.26e-04 | 5 | 137 | 2 | SM00571 | |
| Domain | Ferlin_C | 5.26e-04 | 5 | 137 | 2 | PF16165 | |
| Domain | Ferlin_C | 5.26e-04 | 5 | 137 | 2 | IPR032362 | |
| Domain | FerIin_dom | 5.26e-04 | 5 | 137 | 2 | IPR012968 | |
| Domain | FerI | 5.26e-04 | 5 | 137 | 2 | PF08151 | |
| Domain | FerB | 5.26e-04 | 5 | 137 | 2 | PF08150 | |
| Domain | DDT_dom | 5.26e-04 | 5 | 137 | 2 | IPR018501 | |
| Domain | WHIM1_dom | 5.26e-04 | 5 | 137 | 2 | IPR028942 | |
| Domain | WHIM2_dom | 5.26e-04 | 5 | 137 | 2 | IPR028941 | |
| Domain | zf-C5HC2 | 5.26e-04 | 5 | 137 | 2 | PF02928 | |
| Domain | WSD | 5.26e-04 | 5 | 137 | 2 | PF15613 | |
| Domain | WHIM1 | 5.26e-04 | 5 | 137 | 2 | PF15612 | |
| Domain | Znf_C5HC2 | 5.26e-04 | 5 | 137 | 2 | IPR004198 | |
| Domain | C2 | 6.31e-04 | 142 | 137 | 6 | PS50004 | |
| Domain | - | 7.85e-04 | 148 | 137 | 6 | 2.60.40.150 | |
| Domain | DDT | 7.86e-04 | 6 | 137 | 2 | PS50827 | |
| Domain | EF-hand_dom_typ1 | 7.86e-04 | 6 | 137 | 2 | IPR015153 | |
| Domain | EF-hand_dom_typ2 | 7.86e-04 | 6 | 137 | 2 | IPR015154 | |
| Domain | EF-hand_2 | 7.86e-04 | 6 | 137 | 2 | PF09068 | |
| Domain | EF-hand_3 | 7.86e-04 | 6 | 137 | 2 | PF09069 | |
| Domain | HECT | 9.93e-04 | 27 | 137 | 3 | PF00632 | |
| Domain | HECTc | 9.93e-04 | 27 | 137 | 3 | SM00119 | |
| Domain | HECT_dom | 9.93e-04 | 27 | 137 | 3 | IPR000569 | |
| Domain | HECT | 9.93e-04 | 27 | 137 | 3 | PS50237 | |
| Domain | CYCLINS | 1.11e-03 | 28 | 137 | 3 | PS00292 | |
| Domain | - | 1.27e-03 | 222 | 137 | 7 | 1.25.10.10 | |
| Domain | C2_dom | 1.33e-03 | 164 | 137 | 6 | IPR000008 | |
| Domain | Coatomer/calthrin_app_sub_C | 1.45e-03 | 8 | 137 | 2 | IPR009028 | |
| Domain | Cyclin_N | 1.79e-03 | 33 | 137 | 3 | PF00134 | |
| Domain | Cyclin_N | 1.79e-03 | 33 | 137 | 3 | IPR006671 | |
| Domain | Alpha_adaptinC2 | 1.86e-03 | 9 | 137 | 2 | PF02883 | |
| Domain | Clathrin_a/b/g-adaptin_app_Ig | 1.86e-03 | 9 | 137 | 2 | IPR008152 | |
| Domain | Alpha_adaptinC2 | 1.86e-03 | 9 | 137 | 2 | SM00809 | |
| Domain | ATPase_P-typ_cyto_domN | 2.13e-03 | 35 | 137 | 3 | IPR023299 | |
| Domain | PHD | 2.25e-03 | 75 | 137 | 4 | PF00628 | |
| Domain | ATPase_P-typ_P_site | 2.31e-03 | 36 | 137 | 3 | IPR018303 | |
| Domain | P_typ_ATPase | 2.31e-03 | 36 | 137 | 3 | IPR001757 | |
| Domain | ATPASE_E1_E2 | 2.31e-03 | 36 | 137 | 3 | PS00154 | |
| Domain | JmjN | 2.31e-03 | 10 | 137 | 2 | SM00545 | |
| Domain | JmjN | 2.31e-03 | 10 | 137 | 2 | PF02375 | |
| Domain | JMJN | 2.31e-03 | 10 | 137 | 2 | PS51183 | |
| Domain | JmjN | 2.31e-03 | 10 | 137 | 2 | IPR003349 | |
| Domain | ATPase_P-typ_transduc_dom_A | 2.50e-03 | 37 | 137 | 3 | IPR008250 | |
| Domain | E1-E2_ATPase | 2.50e-03 | 37 | 137 | 3 | PF00122 | |
| Domain | CYCLIN | 2.70e-03 | 38 | 137 | 3 | SM00385 | |
| Domain | HAD-like_dom | 2.72e-03 | 79 | 137 | 4 | IPR023214 | |
| Domain | Znf_PHD-finger | 2.72e-03 | 79 | 137 | 4 | IPR019787 | |
| Domain | - | 3.13e-03 | 40 | 137 | 3 | 1.10.472.10 | |
| Domain | - | 3.17e-03 | 261 | 137 | 7 | 1.10.238.10 | |
| Pathway | WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K | 4.55e-08 | 99 | 104 | 9 | M46448 |
| Pathway | REACTOME_SENSORY_PROCESSING_OF_SOUND | 1.53e-06 | 77 | 104 | 7 | M41822 | |
| Pathway | REACTOME_RHOV_GTPASE_CYCLE | 7.17e-06 | 37 | 104 | 5 | M41819 | |
| Pathway | REACTOME_RHOV_GTPASE_CYCLE | 7.17e-06 | 37 | 104 | 5 | MM15610 | |
| Pathway | REACTOME_NEPHRIN_FAMILY_INTERACTIONS | 2.22e-05 | 23 | 104 | 4 | M913 | |
| Pathway | REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS | 8.18e-05 | 12 | 104 | 3 | M27326 | |
| Pathway | REACTOME_MUSCLE_CONTRACTION | 1.27e-04 | 203 | 104 | 8 | M5485 | |
| Pathway | REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS | 1.34e-04 | 14 | 104 | 3 | MM15052 | |
| Pathway | REACTOME_RHOU_GTPASE_CYCLE | 1.89e-04 | 39 | 104 | 4 | MM15607 | |
| Pathway | REACTOME_RHOU_GTPASE_CYCLE | 2.08e-04 | 40 | 104 | 4 | M41816 | |
| Pathway | REACTOME_LDL_CLEARANCE | 2.94e-04 | 18 | 104 | 3 | MM15565 | |
| Pathway | REACTOME_LDL_CLEARANCE | 3.47e-04 | 19 | 104 | 3 | M27846 | |
| Pathway | REACTOME_SENSORY_PROCESSING_OF_SOUND_BY_OUTER_HAIR_CELLS_OF_THE_COCHLEA | 7.14e-04 | 55 | 104 | 4 | M41823 | |
| Pathway | REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR | 7.35e-04 | 146 | 104 | 6 | MM15292 | |
| Pubmed | TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12. | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 4.15e-27 | 11 | 144 | 11 | 16863688 |
| Pubmed | 2.82e-10 | 4 | 144 | 4 | 8406013 | ||
| Pubmed | DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. | 8.49e-10 | 74 | 144 | 8 | 16625196 | |
| Pubmed | 1.40e-09 | 5 | 144 | 4 | 12604796 | ||
| Pubmed | 1.40e-09 | 5 | 144 | 4 | 8471161 | ||
| Pubmed | KDM5B DIS3L USP9X POLG SPTAN1 SPTBN1 ACTN4 RNF40 EYA3 PRPF8 GTF3C4 CRMP1 WDR3 AP2A1 OTOF SACS VPS35L LRP2 FIBP MAP3K11 UTRN COG4 MITD1 | 3.46e-09 | 1285 | 144 | 23 | 35914814 | |
| Pubmed | 6.95e-08 | 3 | 144 | 3 | 9020840 | ||
| Pubmed | Eyes absent represents a class of protein tyrosine phosphatases. | 6.95e-08 | 3 | 144 | 3 | 14628052 | |
| Pubmed | USP9X KDM5C SPTAN1 SPTBN1 ACTN4 URB2 PRPF8 GTF3C4 CENPP LIPA SACS | 1.54e-07 | 332 | 144 | 11 | 37433992 | |
| Pubmed | Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons. | 2.77e-07 | 4 | 144 | 3 | 12209837 | |
| Pubmed | 2.77e-07 | 4 | 144 | 3 | 12784250 | ||
| Pubmed | Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling. | 2.77e-07 | 4 | 144 | 3 | 18055785 | |
| Pubmed | 2.77e-07 | 4 | 144 | 3 | 23413890 | ||
| Pubmed | Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes. | 2.77e-07 | 4 | 144 | 3 | 8245032 | |
| Pubmed | Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes. | 2.77e-07 | 4 | 144 | 3 | 7989379 | |
| Pubmed | Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps. | 2.77e-07 | 4 | 144 | 3 | 11152753 | |
| Pubmed | PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†. | 2.77e-07 | 4 | 144 | 3 | 36130203 | |
| Pubmed | Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse. | 2.77e-07 | 4 | 144 | 3 | 10434059 | |
| Pubmed | Misexpression of the eyes absent family triggers the apoptotic program. | 2.77e-07 | 4 | 144 | 3 | 11700312 | |
| Pubmed | PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. | 2.77e-07 | 4 | 144 | 3 | 12359748 | |
| Pubmed | 2.77e-07 | 4 | 144 | 3 | 15101689 | ||
| Pubmed | 2.77e-07 | 4 | 144 | 3 | 10577388 | ||
| Pubmed | Structural organization, ion transport, and energy transduction of P-type ATPases. | 2.77e-07 | 4 | 144 | 3 | 8634322 | |
| Pubmed | Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. | IQGAP2 USP9X SPTAN1 SPTBN1 ACTN4 CRMP1 AP2A1 AP2A2 SACS UBR5 | 2.99e-07 | 281 | 144 | 10 | 28706196 |
| Pubmed | Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya. | 6.91e-07 | 5 | 144 | 3 | 10490620 | |
| Pubmed | 6.91e-07 | 5 | 144 | 3 | 9006082 | ||
| Pubmed | 6.91e-07 | 5 | 144 | 3 | 17938178 | ||
| Pubmed | 6.91e-07 | 5 | 144 | 3 | 9195991 | ||
| Pubmed | Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange. | 1.38e-06 | 6 | 144 | 3 | 12767889 | |
| Pubmed | EYA4, a novel vertebrate gene related to Drosophila eyes absent. | 1.38e-06 | 6 | 144 | 3 | 9887327 | |
| Pubmed | The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. | 1.79e-06 | 197 | 144 | 8 | 20811636 | |
| Pubmed | MYO1D IQGAP2 PARP8 SPTAN1 SPTBN1 ACTN4 ACTN3 PRPF8 FER1L6 EHD4 BPTF AP2A1 AP2A2 SACS PKHD1 DMD CCDC191 ATP2B1 ATP2B3 FBXO15 | 2.23e-06 | 1442 | 144 | 20 | 35575683 | |
| Pubmed | PRAMEF5 IQGAP2 POLG SPTBN1 ACTN4 DEPDC1 CRMP1 PRAMEF14 VPS35L LRP2 TIMELESS BAIAP3 ATP2B1 UTRN HERC4 COG4 PRAMEF6 | 2.75e-06 | 1084 | 144 | 17 | 11544199 | |
| Pubmed | 2.83e-06 | 147 | 144 | 7 | 29576527 | ||
| Pubmed | 3.83e-06 | 8 | 144 | 3 | 10951186 | ||
| Pubmed | 6.78e-06 | 313 | 144 | 9 | 20800603 | ||
| Pubmed | 8.13e-06 | 31 | 144 | 4 | 33777788 | ||
| Pubmed | USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells. | 8.17e-06 | 10 | 144 | 3 | 36653359 | |
| Pubmed | 9.17e-06 | 325 | 144 | 9 | 36168628 | ||
| Pubmed | Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking. | 1.09e-05 | 332 | 144 | 9 | 32786267 | |
| Pubmed | Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. | DCAF1 SPTAN1 SPTBN1 FERMT1 ACTN4 CORO1B URB2 PRPF8 GTF3C4 EHD4 WDR3 AP2A1 AP2A2 UBR5 BAZ2A PLCG2 ATP2B1 UTRN | 1.32e-05 | 1353 | 144 | 18 | 29467282 |
| Pubmed | LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow. | 1.44e-05 | 344 | 144 | 9 | 30333137 | |
| Pubmed | 1.62e-05 | 266 | 144 | 8 | 19380743 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 10525423 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 30767316 | ||
| Pubmed | In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice. | 1.70e-05 | 2 | 144 | 2 | 28790199 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 25859846 | ||
| Pubmed | Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy. | 1.70e-05 | 2 | 144 | 2 | 28139640 | |
| Pubmed | G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain. | 1.70e-05 | 2 | 144 | 2 | 7731967 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 16710609 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 18657858 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 30672725 | ||
| Pubmed | Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses. | 1.70e-05 | 2 | 144 | 2 | 37745283 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 7962191 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 8021701 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 26974331 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 28453658 | ||
| Pubmed | A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin. | 1.70e-05 | 2 | 144 | 2 | 11801396 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 7987307 | ||
| Pubmed | Comparative analysis of the human dystrophin and utrophin gene structures. | 1.70e-05 | 2 | 144 | 2 | 11861579 | |
| Pubmed | Distinct mechanical properties in homologous spectrin-like repeats of utrophin. | 1.70e-05 | 2 | 144 | 2 | 30914715 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 22284942 | ||
| Pubmed | Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice. | 1.70e-05 | 2 | 144 | 2 | 17889902 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 35557546 | ||
| Pubmed | Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice. | 1.70e-05 | 2 | 144 | 2 | 37626761 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 15565469 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 26516677 | ||
| Pubmed | Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging. | 1.70e-05 | 2 | 144 | 2 | 22209498 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 37108685 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 10694796 | ||
| Pubmed | Identification of a mouse brain beta-spectrin cDNA and distribution of its mRNA in adult tissues. | 1.70e-05 | 2 | 144 | 2 | 1742606 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 24337461 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 11297940 | ||
| Pubmed | Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins). | 1.70e-05 | 2 | 144 | 2 | 2564002 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 22388933 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 25642938 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 1531651 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 15703201 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 15178683 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 25941878 | ||
| Pubmed | Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link. | 1.70e-05 | 2 | 144 | 2 | 9297964 | |
| Pubmed | SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models. | 1.70e-05 | 2 | 144 | 2 | 25652448 | |
| Pubmed | Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis. | 1.70e-05 | 2 | 144 | 2 | 28785010 | |
| Pubmed | Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations. | 1.70e-05 | 2 | 144 | 2 | 29100090 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 16307000 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 21949353 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 23097179 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 15501597 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 11257121 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 18973234 | ||
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 27881412 | ||
| Pubmed | Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets. | 1.70e-05 | 2 | 144 | 2 | 10748016 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 20625423 | ||
| Pubmed | Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle. | 1.70e-05 | 2 | 144 | 2 | 29065908 | |
| Pubmed | Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy. | 1.70e-05 | 2 | 144 | 2 | 31039133 | |
| Pubmed | 1.70e-05 | 2 | 144 | 2 | 11796130 | ||
| Pubmed | Dystrophin and dystrophin-related protein in the brains of normal and mdx mice. | 1.70e-05 | 2 | 144 | 2 | 8159184 | |
| Pubmed | Dystrophin and utrophin: genetic analyses of their role in skeletal muscle. | 1.70e-05 | 2 | 144 | 2 | 10679963 | |
| Pubmed | TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice. | 1.70e-05 | 2 | 144 | 2 | 21565990 | |
| Pubmed | Generation and characterization of transgenic mice with the full-length human DMD gene. | 1.70e-05 | 2 | 144 | 2 | 18083704 | |
| Interaction | DSCAM interactions | 2.04e-07 | 171 | 133 | 10 | int:DSCAM | |
| Interaction | NOS1 interactions | 5.29e-06 | 67 | 133 | 6 | int:NOS1 | |
| Interaction | AGAP2 interactions | 1.09e-05 | 210 | 133 | 9 | int:AGAP2 | |
| Interaction | LAMTOR1 interactions | IQGAP2 SZT2 SPTBN1 TBC1D22B SLC30A4 EHD4 CCNF AP2A1 AP2A2 LRP2 MME DMD ATP2B1 ATP2B4 COG4 HTT | 2.26e-05 | 722 | 133 | 16 | int:LAMTOR1 |
| Interaction | TACSTD2 interactions | 2.38e-05 | 129 | 133 | 7 | int:TACSTD2 | |
| Interaction | PEX5L interactions | 2.83e-05 | 54 | 133 | 5 | int:PEX5L | |
| Interaction | MEX3A interactions | USP9X KDM5C SPTAN1 SPTBN1 ACTN4 URB2 PRPF8 GTF3C4 CENPP LIPA SACS | 4.93e-05 | 384 | 133 | 11 | int:MEX3A |
| Interaction | ANK3 interactions | 5.75e-05 | 201 | 133 | 8 | int:ANK3 | |
| Interaction | NPPC interactions | 5.92e-05 | 12 | 133 | 3 | int:NPPC | |
| Interaction | C17orf78 interactions | 5.92e-05 | 12 | 133 | 3 | int:C17orf78 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr17q12 | TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3I TBC1D3G TBC1D3K TBC1D3F | 1.87e-12 | 149 | 144 | 11 | chr17q12 |
| Cytoband | 17q12 | 1.60e-05 | 99 | 144 | 5 | 17q12 | |
| Cytoband | 16p13.11 | 5.11e-05 | 23 | 144 | 3 | 16p13.11 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr16p13 | 4.17e-04 | 426 | 144 | 7 | chr16p13 | |
| Cytoband | 18q22.3 | 9.99e-04 | 15 | 144 | 2 | 18q22.3 | |
| Cytoband | 1p36.21 | 1.05e-03 | 63 | 144 | 3 | 1p36.21 | |
| Cytoband | 8q13.3 | 1.61e-03 | 19 | 144 | 2 | 8q13.3 | |
| GeneFamily | EYA transcriptional coactivator and phosphatases | 3.72e-07 | 4 | 83 | 3 | 1044 | |
| GeneFamily | Ferlin family | 1.85e-06 | 6 | 83 | 3 | 828 | |
| GeneFamily | ATPases Ca2+ transporting | 7.68e-06 | 9 | 83 | 3 | 1209 | |
| GeneFamily | Actinins | 1.24e-04 | 4 | 83 | 2 | 1112 | |
| GeneFamily | PRAME family | 1.76e-04 | 24 | 83 | 3 | 686 | |
| GeneFamily | Cyclins | 2.81e-04 | 28 | 83 | 3 | 473 | |
| GeneFamily | EF-hand domain containing|Spectrins | 4.31e-04 | 7 | 83 | 2 | 1113 | |
| GeneFamily | PHD finger proteins | 7.82e-04 | 90 | 83 | 4 | 88 | |
| GeneFamily | X-linked mental retardation|Angiotensin receptors | 1.85e-03 | 53 | 83 | 3 | 103 | |
| GeneFamily | AT-rich interaction domain containing | 2.10e-03 | 15 | 83 | 2 | 418 | |
| GeneFamily | Zinc fingers ZZ-type|Lysine acetyltransferases | 3.04e-03 | 18 | 83 | 2 | 91 | |
| GeneFamily | PHD finger proteins|Lysine demethylases | 5.38e-03 | 24 | 83 | 2 | 485 | |
| CoexpressionAtlas | Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 TBC1D3C TBC1D3B QPCT WDR90 PDGFC TBC1D3G ATP2B1 TBC1D3K TBC1D3F | 2.74e-09 | 281 | 133 | 14 | PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05 |
| CoexpressionAtlas | Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D IQGAP2 TBC1D3C TBC1D3B QPCT WDR90 PDGFC TBC1D3G ATP2B1 TBC1D3K TBC1D3F | 2.74e-09 | 281 | 133 | 14 | PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05 |
| CoexpressionAtlas | Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F | 5.19e-09 | 90 | 133 | 9 | PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05 |
| CoexpressionAtlas | Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D FJX1 TBC1D3C TBC1D3B DIO3 PLCG2 TBC1D3G TBC1D3K TBC1D3F | 8.42e-07 | 320 | 133 | 12 | PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05 |
| CoexpressionAtlas | Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B DIO3 TBC1D3G TBC1D3K TBC1D3F | 9.64e-07 | 213 | 133 | 10 | PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05 |
| CoexpressionAtlas | Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B DIO3 TBC1D3G TBC1D3K TBC1D3F | 9.64e-07 | 213 | 133 | 10 | PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05 |
| CoexpressionAtlas | Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D FJX1 EYA2 TBC1D3C DENND2B TBC1D3B SPATA2L QPCT DIO3 GREB1 MME PLCG2 TBC1D3G BAIAP3 ATP2B1 ATP2B4 TBC1D3K TBC1D3F | 9.86e-06 | 1153 | 133 | 21 | PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05 |
| CoexpressionAtlas | DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05 | TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3C TBC1D3B TBC1D3G TBC1D3K TBC1D3F | 2.23e-05 | 242 | 133 | 9 | PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05 |
| CoexpressionAtlas | dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000 | DCAF1 DYM USP9X URB2 TRIM6 SLC30A4 CENPP TRMT10A BAZ2A HACE1 HFM1 PLCG2 SETD3 CCDC191 FBXO15 HTT | 5.58e-05 | 820 | 133 | 16 | gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000 |
| ToppCell | Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Otof_(Layer_2/3)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32 | 7.94e-07 | 53 | 144 | 5 | a41f66edf468f824494a922c3addf429a9125b7f | |
| ToppCell | renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 8.46e-07 | 158 | 144 | 7 | 1cefb82b9bf79c687a119be568cfc15b14c6e040 | |
| ToppCell | facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.21e-07 | 160 | 144 | 7 | c381ec6be8cf887861cc18f831a20db42f953fe1 | |
| ToppCell | facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.21e-07 | 160 | 144 | 7 | 25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585 | |
| ToppCell | RV-08._Macrophage|World / Chamber and Cluster_Paper | 3.10e-06 | 192 | 144 | 7 | a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3 | |
| ToppCell | Tracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations | 3.92e-06 | 199 | 144 | 7 | 94b94b17ca18b8dc27b91da1f2ccf89e03cc7035 | |
| ToppCell | wk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung | 2.35e-05 | 176 | 144 | 6 | 1af28b701c4598ce761f85adbd5d79e4918d265a | |
| ToppCell | renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 2.42e-05 | 177 | 144 | 6 | da8802a6351d3e510822f82e2fde8a4314a2216e | |
| ToppCell | COVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class | 2.75e-05 | 181 | 144 | 6 | 4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4 | |
| ToppCell | LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 2.75e-05 | 181 | 144 | 6 | b45b11428d13950369347e051d4d517efb2bd4fd | |
| ToppCell | renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 2.83e-05 | 182 | 144 | 6 | e1e58176f533092b6b974ca1ce8b02192a6e193d | |
| ToppCell | wk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung | 2.83e-05 | 182 | 144 | 6 | 0e52ba34e179d9bfaac7b49920b44c710b2b8dad | |
| ToppCell | renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 2.83e-05 | 182 | 144 | 6 | 57bb5a2da976464ba7c4460106bd9f692008ebd9 | |
| ToppCell | Control-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations) | 3.01e-05 | 184 | 144 | 6 | d92a71441e4e19f8c301999d8186f8e48e3cd162 | |
| ToppCell | droplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.20e-05 | 186 | 144 | 6 | 0ae5fbe9f210cb25092394267e1d3d6ed05627b8 | |
| ToppCell | LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 3.30e-05 | 187 | 144 | 6 | 58d48128547ee3513d0bf7f78e61b76b1c472ca9 | |
| ToppCell | renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 3.40e-05 | 188 | 144 | 6 | 63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68 | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 3.50e-05 | 189 | 144 | 6 | e32172ad09e93f6ac6ea2b92145b2b73003f7970 | |
| ToppCell | PND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 3.60e-05 | 190 | 144 | 6 | d67e2814047c8df2ae4b7bc8be9539f5df6ecef2 | |
| ToppCell | Basal_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id | 3.71e-05 | 191 | 144 | 6 | a98915bad9a4a61dd4cbca798914849b805f4a19 | |
| ToppCell | kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 3.82e-05 | 192 | 144 | 6 | 3e1a4cb0d83efd502c8613d41a1692bdda5860ed | |
| ToppCell | TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9 | 3.93e-05 | 193 | 144 | 6 | abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659 | |
| ToppCell | Control-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class | 3.93e-05 | 193 | 144 | 6 | 5896242f713ae5fd1a4ebb63827f15d7279dced2 | |
| ToppCell | COVID-19-Heart-Macrophage|Heart / Disease (COVID-19 only), tissue and cell type | 4.05e-05 | 194 | 144 | 6 | f09675cd472200363c458952f00d2e41990800ee | |
| ToppCell | Parenchymal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 4.41e-05 | 197 | 144 | 6 | 107cb153ea7fc74bbd244dbb9d0499c0a8506724 | |
| ToppCell | Biopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type | 4.79e-05 | 200 | 144 | 6 | 5cea84581201cee7ba8141b96e65864f4fd67113 | |
| ToppCell | PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 5.60e-05 | 126 | 144 | 5 | 518a6e4919981b556ce6b451a91270dba976bc75 | |
| ToppCell | LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 6.50e-05 | 130 | 144 | 5 | 6434d9106ccb38786dad36fab80163dfc07b6eb7 | |
| Drug | Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; MCF7; HT_HG-U133A | 2.77e-06 | 200 | 133 | 9 | 4387_UP | |
| Disease | Hailey-Hailey disease (implicated_via_orthology) | 1.54e-06 | 6 | 127 | 3 | DOID:0050429 (implicated_via_orthology) | |
| Disease | eye disease (implicated_via_orthology) | 1.54e-06 | 6 | 127 | 3 | DOID:5614 (implicated_via_orthology) | |
| Disease | reticulocyte count | MYO1D IQGAP2 GPER1 USP9X EYA1 EYA2 PRPF8 DENND2B EHD4 GREB1L PTPRH PLCG2 PDGFC BAIAP3 ATP2B1 ATP2B4 ALOX5 | 2.61e-06 | 1045 | 127 | 17 | EFO_0007986 |
| Disease | branchiootorenal syndrome (implicated_via_orthology) | 2.69e-06 | 7 | 127 | 3 | DOID:14702 (implicated_via_orthology) | |
| Disease | limb-girdle muscular dystrophy (implicated_via_orthology) | 2.69e-06 | 7 | 127 | 3 | DOID:11724 (implicated_via_orthology) | |
| Disease | reticulocyte measurement | MYO1D IQGAP2 GPER1 USP9X ACTN4 EYA1 EYA2 PRPF8 DENND2B EHD4 PTPRH PLCG2 PDGFC BAIAP3 ATP2B1 ATP2B4 ALOX5 | 2.89e-06 | 1053 | 127 | 17 | EFO_0010700 |
| Disease | CCL4 measurement | 8.41e-05 | 20 | 127 | 3 | EFO_0004751 | |
| Disease | Cryopyrin-Associated Periodic Syndromes | 1.10e-04 | 4 | 127 | 2 | C2316212 | |
| Disease | syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology) | 1.10e-04 | 4 | 127 | 2 | DOID:0060809 (implicated_via_orthology) | |
| Disease | Chronic Infantile Neurological, Cutaneous, and Articular Syndrome | 1.10e-04 | 4 | 127 | 2 | C0409818 | |
| Disease | Familial Cold Autoinflammatory Syndrome 1 | 1.10e-04 | 4 | 127 | 2 | C4551895 | |
| Disease | Familial cold urticaria | 1.10e-04 | 4 | 127 | 2 | C0343068 | |
| Disease | Muckle-Wells Syndrome | 1.82e-04 | 5 | 127 | 2 | C0268390 | |
| Disease | focal segmental glomerulosclerosis 1 (implicated_via_orthology) | 1.82e-04 | 5 | 127 | 2 | DOID:0111128 (implicated_via_orthology) | |
| Disease | macrophage inflammatory protein 1b measurement | 3.13e-04 | 136 | 127 | 5 | EFO_0008219 | |
| Disease | progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma | 6.35e-04 | 39 | 127 | 3 | EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354 | |
| Disease | hypospadias | 6.35e-04 | 39 | 127 | 3 | EFO_0004209 | |
| Disease | myelodysplastic syndrome (implicated_via_orthology) | 1.86e-03 | 15 | 127 | 2 | DOID:0050908 (implicated_via_orthology) | |
| Disease | syndromic intellectual disability (implicated_via_orthology) | 2.12e-03 | 16 | 127 | 2 | DOID:0050888 (implicated_via_orthology) | |
| Disease | erythrocyte cadmium measurement | 2.40e-03 | 17 | 127 | 2 | EFO_0007807 | |
| Disease | gluteofemoral adipose tissue measurement | 2.59e-03 | 132 | 127 | 4 | EFO_0803317 | |
| Disease | C-C motif chemokine 3 measurement | 2.69e-03 | 18 | 127 | 2 | EFO_0008051 | |
| Disease | inosine measurement | 3.00e-03 | 19 | 127 | 2 | EFO_0010503 | |
| Disease | inferior parietal cortex volume measurement | 3.00e-03 | 19 | 127 | 2 | EFO_0010307 | |
| Disease | abnormal paneth cell measurement | 3.00e-03 | 19 | 127 | 2 | EFO_0007963 | |
| Disease | Abdominal Aortic Aneurysm | 3.18e-03 | 68 | 127 | 3 | EFO_0004214 | |
| Disease | BMI-adjusted waist-hip ratio, physical activity measurement | 3.32e-03 | 69 | 127 | 3 | EFO_0007788, EFO_0008002 | |
| Disease | muscular dystrophy (implicated_via_orthology) | 3.66e-03 | 21 | 127 | 2 | DOID:9884 (implicated_via_orthology) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| EVLQATDIDRVFDWI | 511 | Q9UKU6 | |
| IVERLWIYIDNILHS | 66 | Q14146 | |
| ERNQVLTLYLWIRQE | 71 | Q9GZZ6 | |
| ALRTELTEARVQVWF | 166 | Q15699 | |
| LLIVNRYWAQLDETV | 91 | O75150 | |
| DIQYGREESDWTIVL | 371 | P54687 | |
| IYEIEQHKIETWREI | 261 | Q9UGI9 | |
| TFRQLERLVAEEAWV | 631 | O94812 | |
| ILNLERVTEILDYWG | 736 | Q9H9E3 | |
| YETDLAVLQWVEELE | 1511 | Q9UIF9 | |
| QLYEQARWAILLEEI | 291 | Q9BQL6 | |
| IWTIILRFAIQDISV | 146 | O43707 | |
| EEVVLWLLRLQNTFY | 151 | Q6ZMN8 | |
| VWYRVLQIVTNRDDV | 461 | O95782 | |
| VVLIWNVGTAEELYR | 156 | Q9BR76 | |
| ELELQILTEAIRNWE | 456 | Q14155 | |
| LDRYQTALEEVLSWL | 341 | P11532 | |
| YRTLELELLEWQERE | 681 | P78524 | |
| WFLNRRLIIEEDTEN | 471 | Q12830 | |
| FELVIVWRIQIDEDG | 216 | Q6IPU0 | |
| LVWEALQDVTLIILE | 101 | P20020 | |
| LVWEALQDVTLIILE | 101 | Q16720 | |
| LVWEALQDVTLIILE | 96 | P23634 | |
| RAILVDWLVEVQVSF | 1161 | Q8WWL7 | |
| VSEEVWYRVIQIVIN | 456 | O94973 | |
| LKLYSDEQWVEVERT | 46 | O95741 | |
| FRDQVILLEEAWSEL | 246 | Q9Y5X4 | |
| QRLQADWVLEIDTFL | 96 | Q16769 | |
| ELERVFLWDLDETII | 301 | Q99504 | |
| ESVLDILTEQREWVL | 186 | Q68E01 | |
| IVLEDIFTLWRQVET | 101 | Q9UND3 | |
| RLVAVEENVWIQLTF | 76 | Q9NRA1 | |
| LEVIINTEIWDLRTF | 1271 | Q9Y4B6 | |
| FLDEEIAVAWEVIRT | 191 | Q8N3A8 | |
| QTVVRLELEDEWQFR | 1911 | Q4ZG55 | |
| QVSELRTWLERYDEQ | 281 | P55073 | |
| SYELRVVIWNTEDVV | 1491 | A9Z1Z3 | |
| AWLVLDSVVDVIFLV | 246 | Q8NCM2 | |
| VQELIDIRNDYINWV | 621 | Q5GLZ8 | |
| LERVFIWDLDETIIV | 321 | Q99502 | |
| VVREWFDILSNEIVN | 596 | Q8IYU2 | |
| QIREVFIQTLDDLTW | 446 | P08473 | |
| LSQEDVEEVWRYVIL | 181 | Q5TB30 | |
| AIWQTVEELDYLEVE | 686 | P54098 | |
| VVFDISVIRALWETR | 6 | Q9BYS8 | |
| QVLQWFAERVDRIIL | 176 | Q9H223 | |
| WRLVSTIEEDVTVEY | 411 | Q9UGL1 | |
| ISETTRDYWVITVLQ | 1051 | Q6ZVL6 | |
| EEDLLYWVDASLQRI | 2561 | P98164 | |
| IIESWLRKQIYSVDQ | 141 | P16885 | |
| IVLEDIFTLWRQVET | 101 | F8WFD2 | |
| TIVRLELEDEWQFRL | 1886 | Q9C091 | |
| DVNIAVEWIRSTLLY | 711 | A2PYH4 | |
| AELVDLVQWTDLILF | 281 | Q86VR8 | |
| YWLVRTELLETLAEI | 861 | P42858 | |
| ILTIREAVWLTDNTY | 371 | P41002 | |
| NITWYSERVLTEISL | 421 | Q7RTS9 | |
| HVELVWIRETEEYLI | 476 | Q8NCQ5 | |
| WIRETEEYLIVNLVL | 481 | Q8NCQ5 | |
| SQDWFILVSVIADLR | 26 | P35575 | |
| VERNLVRVAEVWLDE | 741 | Q7Z7M9 | |
| TLQDFRVVVRIDSWE | 386 | Q8TF46 | |
| IFDSIIVIISIWEIV | 706 | Q9P0X4 | |
| IIFVLIIWTETLADQ | 6 | A8TX70 | |
| LIIYEETTDIWINIH | 436 | Q6V1X1 | |
| QSWLQYVIDLQEEVR | 816 | Q8NCU4 | |
| SLQEDVTWELVVLRR | 446 | Q86WZ0 | |
| YDIEWLTILRATDDL | 281 | Q9UK59 | |
| TIEDLEEWTEYRVQV | 1161 | Q58EX2 | |
| VIYSISCDWVRLEQV | 561 | Q9NZJ4 | |
| WEELELVREEVTFIY | 146 | P0C7I6 | |
| ITSWYDGVREELEVL | 141 | Q14194 | |
| AQWELEVFERELTLL | 446 | Q16584 | |
| KYELRVIIWNTDEVV | 1731 | Q9HC10 | |
| LYLQVDQRWVEDTVG | 636 | Q6ZRI0 | |
| VIFLRWDFDLEAEII | 41 | A6NHM9 | |
| IVLEDIFTLWRQVET | 101 | E9PJI5 | |
| IVLEDIFTLWRQVET | 101 | P0DM63 | |
| EIERVFVWDLDETII | 266 | O00167 | |
| NTTLIDEDVYRLWLD | 11 | O43427 | |
| YELRVTIWNTEDVIL | 1596 | Q2WGJ9 | |
| VLVLQVWDFERLSSD | 1691 | Q2WGJ9 | |
| IESWVRLQDEYDSVL | 56 | Q9UGM6 | |
| DFWLIVRVLQDRVEV | 1916 | Q5T011 | |
| YTDVVETRLSQWLEE | 171 | O14804 | |
| LDYLWRVVIQSNDDI | 771 | Q93008 | |
| LDSYQIALEEVLTWL | 311 | P46939 | |
| YLDLETTWLNTLEER | 1241 | P46939 | |
| ARQFIISWILVLESV | 191 | Q08AM6 | |
| LRAVLWQILVEDFDL | 31 | Q8IUW3 | |
| LVQEIFERILFIWAI | 286 | Q9NU19 | |
| LLVWEAIRTFTAEVV | 476 | P09917 | |
| LFREYLNETVTEVWI | 106 | Q8WV92 | |
| IVLEDIFTLWRQVET | 101 | E9PKD4 | |
| EESLNSLVRVDWEIF | 416 | Q5SWL7 | |
| QVFEQWLLTDLRDLE | 51 | Q9H9A7 | |
| YIRENIWSASEELLL | 651 | Q13576 | |
| VREVQWLEVTLGFIV | 211 | Q99527 | |
| WDQVITLDQVLDEVI | 11 | Q8NEK8 | |
| EWEEYVQIRTLVEKI | 46 | Q86TU7 | |
| IEDARWFTREQVLDV | 416 | Q9BQG2 | |
| WEIVILERLTNFLQI | 3576 | P08F94 | |
| LTLRLWDVYLVEGEQ | 281 | B9A6J9 | |
| WTIILRFQIQDISVE | 151 | Q01082 | |
| IWTIILRFAIQDISV | 141 | Q08043 | |
| VDYIVISDNLWISQR | 221 | Q96KN2 | |
| IIWFVDDTNVYRVTI | 1776 | Q6P2Q9 | |
| EVLEERTRIQFIRWS | 106 | Q7Z5L4 | |
| LTLRLWDVYLVEGEQ | 281 | A6NDS4 | |
| LTLRLWDVYLVEGEQ | 281 | P0C7X1 | |
| VELWLKNRTLDEYLT | 151 | Q5VXH4 | |
| TLYELLQLGWEERQE | 136 | Q9UNS1 | |
| ETNIIGTWEVFINLR | 161 | I1YAP6 | |
| LLFTAARNEILVWEV | 1731 | Q96KV7 | |
| FLVRELLNVIQDYTW | 796 | Q7Z3J2 | |
| YLLDLRTWQEEKSVV | 1701 | Q99973 | |
| LTLRLWDVYLVEGEQ | 281 | A6NER0 | |
| YVAWVREEVTQRIAT | 741 | Q8N271 | |
| LEQREIWLLVTDVTL | 666 | Q14159 | |
| RDTLTEQLRWLTVFQ | 1296 | O75038 | |
| LQQLFRDVEDEETWI | 786 | Q13813 | |
| VELWLKNRTLDEYLT | 151 | Q5TYX0 | |
| LTLRLWDVYLVEGEQ | 281 | A0A087X179 | |
| QWVQLVDLTEIYGER | 201 | Q9UKN8 | |
| ENIETFLSILESLWI | 611 | Q9H330 | |
| FRIIWDTVVIILEGV | 321 | O14863 | |
| IEDVYSVEDLNIWSL | 351 | O14863 | |
| NWLDFSVTVFEVIIR | 181 | Q01118 | |
| VFEIILEYLETRDWQ | 251 | Q8TBZ6 | |
| WIEIEARIRLSFAQV | 181 | Q5W5X9 | |
| LTLRLWDVYLVEGEQ | 281 | A0A087WVF3 | |
| IIVWDVINESGLYRL | 131 | Q9UNX4 | |
| LTLRLWDVYLVEGEQ | 281 | Q6DHY5 | |
| LTLRLWDVYLVEGEQ | 281 | Q8IZP1 | |
| ENWTVRELLLLQVEE | 956 | Q9HD43 | |
| LTLRLWDVYLVEGEQ | 281 | A0A087X1G2 | |
| TLRLWDVYLVEGEQV | 281 | P35125 | |
| LSDTIEVYQERIQWL | 141 | A6NCI4 | |
| LTLRLWDVYLVEGEQ | 281 | A0A087WXS9 | |
| LTLRLWDVYLVEGEQ | 281 | Q6IPX1 | |
| RELTDVQSYWVDVTL | 291 | Q9C030 | |
| VISWLEEEELRTLQQ | 61 | Q96MR9 | |
| VNEEQWSLREVVFVE | 646 | O95071 | |
| TREEWQNVFLIAALV | 476 | Q8NDX2 | |
| IIYVTDLIVDIWVSV | 16 | Q5GH70 | |
| WRLVNSIEEDVTVEY | 426 | P41229 | |
| WLADVYDVNILLTQI | 346 | P38571 | |
| LFCWIVTRINDIIEV | 351 | O94832 |