Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	IMP dehydrogenase activity	IMPDH1 IMPDH2	4.67e-05	2	137	2	GO:0003938
GeneOntologyMolecularFunction	potassium ion leak channel activity	KCNK1 KCNK10 KCNK6	1.66e-04	16	137	3	GO:0022841
GeneOntologyMolecularFunction	potassium channel activity	TRPM5 KCNA4 KCNK1 KCNK10 KCNAB1 KCNK6	2.55e-04	128	137	6	GO:0005267
GeneOntologyMolecularFunction	narrow pore channel activity	KCNK1 KCNK10 KCNK6	2.82e-04	19	137	3	GO:0022842
GeneOntologyMolecularFunction	leak channel activity	KCNK1 KCNK10 KCNK6	2.82e-04	19	137	3	GO:0022840
GeneOntologyBiologicalProcess	epithelium development	SOX4 WHRN PRKD2 FLNA SHROOM3 GAK LAMA1 E2F7 EPB41L5 LAMA5 TRIM71 LHX3 KRT79 MEOX1 NFATC4 GLI3 DCHS1 B9D1 UPK3A DMBT1 CSMD1 CDC42 ADAMTSL4 PCK2 FOXF1 NOTCH4 SMAD7	1.15e-06	1469	137	27	GO:0060429
GeneOntologyBiologicalProcess	epithelial cell differentiation	SOX4 WHRN FLNA SHROOM3 GAK LAMA1 E2F7 EPB41L5 LHX3 KRT79 B9D1 UPK3A DMBT1 CDC42 ADAMTSL4 PCK2 FOXF1 NOTCH4	1.87e-05	870	137	18	GO:0030855
GeneOntologyBiologicalProcess	tissue morphogenesis	PRKD2 FLNA SHROOM3 LAMA1 EPB41L5 LAMA5 TRIM71 NFATC4 GLI3 DCHS1 PRKAR1A CSMD1 CDC42 FOXF1 NOTCH4 SMAD7	3.92e-05	750	137	16	GO:0048729
GeneOntologyBiologicalProcess	branching morphogenesis of an epithelial tube	LAMA1 LAMA5 NFATC4 GLI3 DCHS1 CSMD1 FOXF1 NOTCH4	5.44e-05	198	137	8	GO:0048754
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	LAMA1 LAMA5 HNRNPK NFATC4 GLI3 DCHS1 CSMD1 FOXF1 NOTCH4	5.81e-05	258	137	9	GO:0001763
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	PRKD2 FLNA SHROOM3 LAMA1 EPB41L5 LAMA5 TRIM71 NFATC4 GLI3 DCHS1 CSMD1 CDC42 FOXF1 NOTCH4	6.61e-05	619	137	14	GO:0002009
GeneOntologyBiologicalProcess	animal organ morphogenesis	SOX4 WHRN FLNA GAK CDX4 DSCAM SOBP LAMA1 LAMA5 NBL1 LHX3 ACAN GLI3 DCHS1 PRKAR1A PRKAR1B ROM1 CSMD1 CDC42 FOXF1 SMAD7	9.61e-05	1269	137	21	GO:0009887
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	PRKD2 SHROOM3 LAMA1 LAMA5 TRIM71 NFATC4 GLI3 DCHS1 CSMD1 FOXF1 NOTCH4	1.19e-04	421	137	11	GO:0060562
GeneOntologyBiologicalProcess	morphogenesis of a polarized epithelium	LAMA1 LAMA5 DCHS1 CDC42 FOXF1	1.26e-04	73	137	5	GO:0001738
GeneOntologyBiologicalProcess	regulation of establishment of protein localization	SOX4 FLNA ANK3 EPB41L5 CEP192 ACVR1C CEMIP OXCT1 SLC16A1 GLI3 SLC35D3 PRKAR1A CDC42 PCK2	1.62e-04	674	137	14	GO:0070201
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	FLNA ANK3 TRPM5 KCNA4 KCNK1 KCNK10 KCNAB1 KCNK6	1.63e-04	232	137	8	GO:0071805
GeneOntologyBiologicalProcess	stabilization of membrane potential	KCNK1 KCNK10 KCNK6	1.82e-04	17	137	3	GO:0030322
GeneOntologyBiologicalProcess	morphogenesis of a branching epithelium	LAMA1 LAMA5 NFATC4 GLI3 DCHS1 CSMD1 FOXF1 NOTCH4	1.84e-04	236	137	8	GO:0061138
GeneOntologyBiologicalProcess	mesenchyme development	SOX4 FLNA EPB41L5 LAMA5 MEOX1 DCHS1 CDC42 FOXF1 NOTCH4 SMAD7	1.95e-04	372	137	10	GO:0060485
GeneOntologyBiologicalProcess	cell-cell adhesion	SOX4 FLNA ANK3 DSCAM F2RL3 EPB41L5 ACTL6A ADGRV1 PTPRU NPHP4 HMCN1 GLI3 DCHS1 PRKAR1A CDC42 FOXF1 NOTCH4 SMAD7	2.82e-04	1077	137	18	GO:0098609
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	WHRN PRKD2 FLNA FLNC KRT8 SHROOM3 DSCAM CAPN3 E2F7 EPB41L5 TRIM71 ACTL6A MEOX1 FIG4 NFATC4 GLI3 DCHS1 PRKAR1A EMC10 CDC42 FOXF1 NOTCH4	3.07e-04	1483	137	22	GO:0048646
GeneOntologyBiologicalProcess	regulation of protein localization	SOX4 FLNA ANK3 EPB41L5 CEP192 ACVR1C HNRNPK GSN CEMIP OXCT1 SLC16A1 GLI3 SLC35D3 PRKAR1A B9D1 CDC42 PCK2 NOTCH4	3.15e-04	1087	137	18	GO:0032880
GeneOntologyBiologicalProcess	establishment of epithelial cell apical/basal polarity	LAMA1 CDC42 FOXF1	3.49e-04	21	137	3	GO:0045198
GeneOntologyBiologicalProcess	cell morphogenesis	WHRN FLNA SHROOM3 ANK3 DSCAM LAMA1 EPB41L5 LAMA5 NBL1 LHX3 HNRNPK STRIP1 SHROOM1 NFATC4 GLI3 UPK3A CDC42 MOV10 NOTCH4	3.49e-04	1194	137	19	GO:0000902
GeneOntologyBiologicalProcess	neuroepithelial cell differentiation	SOX4 GAK LHX3 B9D1	3.65e-04	51	137	4	GO:0060563
GeneOntologyBiologicalProcess	positive regulation of establishment of protein localization	SOX4 FLNA ANK3 CEMIP OXCT1 GLI3 SLC35D3 PRKAR1A CDC42 PCK2	3.68e-04	403	137	10	GO:1904951
GeneOntologyCellularComponent	cell-cell junction	FLNA KRT8 SHROOM3 ANK3 FRMPD2 LAMA1 EPB41L5 MAGI3 PTPRU NPHP4 GSN SHROOM1 HMCN1 CDC42 SMAD7 PDZD2	2.28e-06	591	140	16	GO:0005911
GeneOntologyCellularComponent	anchoring junction	FLNA FLNC KRT8 SHROOM3 GAK ANK3 FRMPD2 LAMA1 EPB41L5 MAGI3 PTPRU NPHP4 HNRNPK GSN SHROOM1 HMCN1 CDC42 TNS1 SMAD7 PDZD2	8.10e-06	976	140	20	GO:0070161
GeneOntologyCellularComponent	USH2 complex	WHRN ADGRV1	2.65e-04	4	140	2	GO:1990696
GeneOntologyCellularComponent	costamere	FLNC KRT8 ANK3	4.12e-04	22	140	3	GO:0043034
GeneOntologyCellularComponent	ciliary base	NPHP4 GLI3 PRKAR1A PRKAR1B	5.40e-04	56	140	4	GO:0097546
GeneOntologyCellularComponent	stereocilia ankle link	WHRN ADGRV1	6.56e-04	6	140	2	GO:0002141
GeneOntologyCellularComponent	stereocilia ankle link complex	WHRN ADGRV1	6.56e-04	6	140	2	GO:0002142
GeneOntologyCellularComponent	periciliary membrane compartment	WHRN ADGRV1	6.56e-04	6	140	2	GO:1990075
GeneOntologyCellularComponent	apical junction complex	SHROOM3 ANK3 FRMPD2 MAGI3 NPHP4 SHROOM1	6.92e-04	158	140	6	GO:0043296
GeneOntologyCellularComponent	pericentriolar material	TUBG2 CEP192 TUBG1	8.52e-04	28	140	3	GO:0000242
GeneOntologyCellularComponent	stereocilia coupling link	WHRN ADGRV1	1.21e-03	8	140	2	GO:0002139
Domain	Pectin_lyase_fold/virulence	PKHD1L1 CEMIP SHCBP1L	2.20e-05	8	139	3	IPR011050
Domain	IG_FLMN	FLNA FLNC TRIM71	4.66e-05	10	139	3	SM00557
Domain	IMP_DH	IMPDH1 IMPDH2	5.50e-05	2	139	2	IPR005990
Domain	Gamma_tubulin	TUBG2 TUBG1	5.50e-05	2	139	2	IPR002454
Domain	Filamin	FLNA FLNC TRIM71	6.37e-05	11	139	3	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNC TRIM71	6.37e-05	11	139	3	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNC TRIM71	6.37e-05	11	139	3	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNC TRIM71	6.37e-05	11	139	3	IPR017868
Domain	2pore_dom_K_chnl_TWIK	KCNK1 KCNK6	1.64e-04	3	139	2	IPR005408
Domain	ASD1	SHROOM3 SHROOM1	1.64e-04	3	139	2	PF08688
Domain	ASD1_dom	SHROOM3 SHROOM1	1.64e-04	3	139	2	IPR014800
Domain	ASD1	SHROOM3 SHROOM1	1.64e-04	3	139	2	PS51306
Domain	2pore_dom_K_chnl	KCNK1 KCNK10 KCNK6	1.72e-04	15	139	3	IPR003280
Domain	IMPDH	IMPDH1 IMPDH2	3.27e-04	4	139	2	PF00478
Domain	G8_domain	PKHD1L1 CEMIP	3.27e-04	4	139	2	IPR019316
Domain	G8	PKHD1L1 CEMIP	3.27e-04	4	139	2	PS51484
Domain	IMP_DH_GMPRt	IMPDH1 IMPDH2	3.27e-04	4	139	2	IPR001093
Domain	Shroom_fam	SHROOM3 SHROOM1	3.27e-04	4	139	2	IPR027685
Domain	cAMP_dep_PK_reg_su	PRKAR1A PRKAR1B	3.27e-04	4	139	2	IPR012198
Domain	IMP_DH_GMP_RED	IMPDH1 IMPDH2	3.27e-04	4	139	2	PS00487
Domain	IMP_DH/GMP_Rdtase_CS	IMPDH1 IMPDH2	3.27e-04	4	139	2	IPR015875
Domain	G8	PKHD1L1 CEMIP	3.27e-04	4	139	2	SM01225
Domain	ASD2_dom	SHROOM3 SHROOM1	3.27e-04	4	139	2	IPR014799
Domain	ASD2	SHROOM3 SHROOM1	3.27e-04	4	139	2	PF08687
Domain	G8	PKHD1L1 CEMIP	3.27e-04	4	139	2	PF10162
Domain	ASD2	SHROOM3 SHROOM1	3.27e-04	4	139	2	PS51307
Domain	K_chnl_dom	KCNK1 KCNK10 KCNK6	4.86e-04	21	139	3	IPR013099
Domain	Ion_trans_2	KCNK1 KCNK10 KCNK6	4.86e-04	21	139	3	PF07885
Domain	Laminin_domII	LAMA1 LAMA5	5.42e-04	5	139	2	IPR010307
Domain	Laminin_aI	LAMA1 LAMA5	5.42e-04	5	139	2	IPR009254
Domain	Laminin_I	LAMA1 LAMA5	5.42e-04	5	139	2	PF06008
Domain	Laminin_II	LAMA1 LAMA5	5.42e-04	5	139	2	PF06009
Domain	Pectin_lyas_fold	CEMIP SHCBP1L	8.09e-04	6	139	2	IPR012334
Domain	PbH1	PKHD1L1 SHCBP1L	8.09e-04	6	139	2	SM00710
Domain	-	CEMIP SHCBP1L	8.09e-04	6	139	2	2.160.20.10
Domain	RIIa	PRKAR1A PRKAR1B	8.09e-04	6	139	2	SM00394
Domain	PbH1	PKHD1L1 SHCBP1L	8.09e-04	6	139	2	IPR006626
Domain	Ig_E-set	FLNA FLNC TRIM71 PKHD1L1 NFATC4	1.08e-03	104	139	5	IPR014756
Domain	RIIa	PRKAR1A PRKAR1B	1.13e-03	7	139	2	PF02197
Domain	PTEN_C2	GAK TNS1	1.50e-03	8	139	2	PF10409
Domain	PTEN_C2	GAK TNS1	1.50e-03	8	139	2	SM01326
Domain	C2_TENSIN	GAK TNS1	1.50e-03	8	139	2	PS51182
Domain	Tensin_lipid_phosphatase_dom	GAK TNS1	1.50e-03	8	139	2	IPR029023
Domain	LAMININ_IVA	LAMA1 LAMA5	1.50e-03	8	139	2	PS51115
Domain	Laminin_B	LAMA1 LAMA5	1.50e-03	8	139	2	PF00052
Domain	Tensin_C2-dom	GAK TNS1	1.50e-03	8	139	2	IPR014020
Domain	LamB	LAMA1 LAMA5	1.50e-03	8	139	2	SM00281
Domain	Laminin_IV	LAMA1 LAMA5	1.50e-03	8	139	2	IPR000034
Domain	PPASE_TENSIN	GAK TNS1	1.91e-03	9	139	2	PS51181
Domain	2pore_dom_K_chnl_TASK	KCNK1 KCNK6	1.91e-03	9	139	2	IPR003092
Domain	GPS	ADGRV1 PKD1L2 ADGRF3	2.04e-03	34	139	3	SM00303
Domain	GPS	ADGRV1 PKD1L2 ADGRF3	2.22e-03	35	139	3	PF01825
Domain	GPS	ADGRV1 PKD1L2 ADGRF3	2.41e-03	36	139	3	PS50221
Domain	GPS	ADGRV1 PKD1L2 ADGRF3	2.60e-03	37	139	3	IPR000203
Pathway	WP_NPHP1_DELETION_SYNDROME	FLNA FLNC NPHP4	6.90e-05	11	108	3	M48099
Pathway	REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS	KCNK1 KCNK10 KCNK6	6.90e-05	11	108	3	MM14547
Pathway	REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS	KCNK1 KCNK10 KCNK6	9.15e-05	12	108	3	M1071
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	FLNA FLNC DPYSL2 KRT8 IMPDH1 CDK12 SOBP EPB41L5 KRT79 NPHP4 GSN PLEKHG1 OXCT1 GLI3 B9D1	1.10e-08	564	141	15	21565611
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 DPYSL2 SHROOM3 IMPDH2 ANK3 DSCAM WDR7 HNRNPK GSN STRIP1 SLC7A3 KCNA4 ZC3H4 DCHS1 PRKAR1A PRKAR1B KCNAB1 TNS1	7.81e-08	963	141	18	28671696
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WHRN WDR7 TSPOAP1 AVL9 PPRC1 CEP192 STRIP1 PLEKHG1 RHOBTB2 KATNIP MCF2L PDZD2	1.15e-07	407	141	12	12693553
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FLNC DPYSL2 KRT8 IMPDH2 WDR7 CDK12 TRIM71 PRPF6 ACTL6A AGPS TUBG1 HNRNPK TBC1D10B SF3B3 SLC16A1 ZC3H4 DYNC1LI1 CATSPERG	4.31e-07	1082	141	18	38697112
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	DPYSL2 ADAMTS4 LAMA1 LAMA5	4.54e-07	16	141	4	30579834
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SOX4 PRKD2 FLNA FLNC SHROOM3 IMPDH1 PPRC1 CDK12 LAMA5 NBL1 CEP192 NPHP4 TUBG1 TBC1D16 PLEKHG1 MCF2L RGL2 SMAD7	5.84e-07	1105	141	18	35748872
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNC NPHP4	6.48e-07	5	141	3	12006559
Pubmed	Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia.	TUBG2 TUBG1 GLI3	6.48e-07	5	141	3	31390572
Pubmed	A human MAP kinase interactome.	FLNA FLNC KRT8 ANK3 MIDEAS HNRNPK MSL2 PRKAR1A PRKAR1B CDC42 RGL2 TNS1	7.58e-07	486	141	12	20936779
Pubmed	Disruption of a ciliary B9 protein complex causes Meckel syndrome.	TUBG2 TUBG1 GLI3 B9D1	7.58e-07	18	141	4	21763481
Pubmed	Cilia and Hedgehog responsiveness in the mouse.	TUBG2 LHX3 TUBG1 GLI3	9.57e-07	19	141	4	16061793
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	FLNA FLNC DPYSL2 KRT8 IMPDH2 ANK3 CDK12 PRPF6 ACTL6A TUBG1 HNRNPK GSN SF3B3 ZC3H4 PRKAR1A DYNC1LI1 CDC42 MOV10	1.02e-06	1149	141	18	35446349
Pubmed	Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.	KRT8 LAMA1 LAMA5	1.29e-06	6	141	3	15668394
Pubmed	TMEM216 promotes primary ciliogenesis and Hedgehog signaling through the SUFU-GLI2/GLI3 axis.	TUBG2 TUBG1 GLI3	2.26e-06	7	141	3	38261656
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNA FLNC DPYSL2 KRT8 GAK TUBG1 HNRNPK GSN DHRS4 DYNC1LI1	2.32e-06	360	141	10	33111431
Pubmed	Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling.	TUBG2 NPHP4 TUBG1	3.60e-06	8	141	3	26540106
Pubmed	A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder.	LAMA1 LAMA5 UPK3A	3.60e-06	8	141	3	32439764
Pubmed	The small GTPase RSG1 controls a final step in primary cilia initiation.	TUBG2 NPHP4 TUBG1 GLI3	4.91e-06	28	141	4	29038301
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	RNF169 IMPDH1 UBE2Q1 CENPC FKBP9 ACTL6A TUBG1 CASKIN2 PRKAR1A B9D1 CATSPERG PCK2 FOXF1	5.03e-06	689	141	13	36543142
Pubmed	Centriolar Protein C2cd3 Is Required for Craniofacial Development.	TUBG2 TUBG1 GLI3	5.38e-06	9	141	3	34211969
Pubmed	Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation.	KRT8 LAMA1 LAMA5	5.38e-06	9	141	3	15102706
Pubmed	Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality.	KRT8 LAMA1 LAMA5	5.38e-06	9	141	3	30456378
Pubmed	Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.	KRT8 COL20A1 LAMA1 UPK3A	7.48e-06	31	141	4	22282597
Pubmed	Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries.	KRT8 LAMA1 LAMA5	7.67e-06	10	141	3	22911783
Pubmed	Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1.	TUBG2 TUBG1 ROM1	7.67e-06	10	141	3	20592197
Pubmed	A role for primary cilia in aortic valve development and disease.	TUBG2 TUBG1 GLI3	7.67e-06	10	141	3	28556366
Pubmed	Primary cilia are critical for tracheoesophageal septation.	TUBG2 TUBG1 GLI3	1.05e-05	11	141	3	37776236
Pubmed	Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate.	TUBG2 TUBG1 GLI3	1.40e-05	12	141	3	28069795
Pubmed	Potassium leak channels and the KCNK family of two-P-domain subunits.	KCNK1 KCNK10 KCNK6	1.40e-05	12	141	3	11256078
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	KRT8 LAMA1 LAMA5	1.40e-05	12	141	3	16750824
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	FLNA E2F7 PRPF6 ACTL6A HNRNPK SF3B3 PRKAR1A DMBT1	1.63e-05	272	141	8	31010829
Pubmed	Mass Spectrometry and Computer Simulation Predict the Interactions of AGPS and HNRNPK in Glioma.	AGPS HNRNPK	1.63e-05	2	141	2	34621897
Pubmed	Expression of IMPDH mRNA after mycophenolate administration in male volunteers.	IMPDH1 IMPDH2	1.63e-05	2	141	2	25105143
Pubmed	Promoter for the regulatory type I beta subunit of the 3',5'-cyclic adenosine monophosphate-dependent protein kinase directs transgene expression in the central nervous system.	PRKAR1A PRKAR1B	1.63e-05	2	141	2	1448119
Pubmed	Pharmacogenetics of the mycophenolic acid targets inosine monophosphate dehydrogenases IMPDH1 and IMPDH2: gene sequence variation and functional genomics.	IMPDH1 IMPDH2	1.63e-05	2	141	2	20718729
Pubmed	The laminin response in inflammatory bowel disease: protection or malignancy?	LAMA1 LAMA5	1.63e-05	2	141	2	25347196
Pubmed	Two distinct cDNAs for human IMP dehydrogenase.	IMPDH1 IMPDH2	1.63e-05	2	141	2	1969416
Pubmed	[Correlation between ultrastructural changes of glomerular basement membrane and abnormal distribution of laminins in patients with Alport's syndrome].	LAMA1 LAMA5	1.63e-05	2	141	2	20019771
Pubmed	MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.	TUBG2 TUBG1	1.63e-05	2	141	2	17442887
Pubmed	Azilsartan prevented AGE-induced inflammatory response and degradation of aggrecan in human chondrocytes through inhibition of Sox4.	SOX4 ACAN	1.63e-05	2	141	2	34051020
Pubmed	Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments.	ADAMTS4 ACAN	1.63e-05	2	141	2	16188468
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	1.63e-05	2	141	2	7689010
Pubmed	Overexpression of γ-tubulin in non-small cell lung cancer.	TUBG2 TUBG1	1.63e-05	2	141	2	22806905
Pubmed	Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4).	ADAMTS4 ACAN	1.63e-05	2	141	2	10751421
Pubmed	Targeted disruption of the inosine 5'-monophosphate dehydrogenase type I gene in mice.	IMPDH1 IMPDH2	1.63e-05	2	141	2	12944494
Pubmed	Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.	MCF2L CDC42	1.63e-05	2	141	2	17704816
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	1.63e-05	2	141	2	10679933
Pubmed	Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.	TUBG2 TUBG1	1.63e-05	2	141	2	17287496
Pubmed	Cloning and sequence analysis of the human and Chinese hamster inosine-5'-monophosphate dehydrogenase cDNAs.	IMPDH1 IMPDH2	1.63e-05	2	141	2	2902093
Pubmed	Characterization of human type I and type II IMP dehydrogenases.	IMPDH1 IMPDH2	1.63e-05	2	141	2	7903306
Pubmed	Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor binding.	IMPDH1 IMPDH2	1.63e-05	2	141	2	7763314
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	1.63e-05	2	141	2	24469451
Pubmed	Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.	TUBG2 TUBG1	1.63e-05	2	141	2	28119396
Pubmed	Presynaptic congenital myasthenic syndrome with a homozygous sequence variant in LAMA5 combines myopia, facial tics, and failure of neuromuscular transmission.	LAMA1 LAMA5	1.63e-05	2	141	2	28544784
Pubmed	Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo.	IMPDH1 IMPDH2	1.63e-05	2	141	2	14766016
Pubmed	Targeting SOX4/PCK2 signaling suppresses neuroendocrine trans-differentiation of castration-resistant prostate cancer.	SOX4 PCK2	1.63e-05	2	141	2	39014441
Pubmed	Characterization of the human inosine-5'-monophosphate dehydrogenase type II gene.	IMPDH1 IMPDH2	1.63e-05	2	141	2	7896827
Pubmed	Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil.	IMPDH1 IMPDH2	1.63e-05	2	141	2	20679962
Pubmed	Expression of inosine monophosphate dehydrogenase type I and type II after mycophenolate mofetil treatment: a 2-year follow-up in kidney transplantation.	IMPDH1 IMPDH2	1.63e-05	2	141	2	17713475
Pubmed	The contribution of GPR98 and DFNB31 genes to a Spanish Usher syndrome type 2 cohort.	WHRN ADGRV1	1.63e-05	2	141	2	23441107
Pubmed	Mutants of purine metabolism in cultured mouse and hamster cells.	IMPDH1 IMPDH2	1.63e-05	2	141	2	988789
Pubmed	ADAMTS-4_v1 is a splice variant of ADAMTS-4 that is expressed as a protein in human synovium and cleaves aggrecan at the interglobular domain.	ADAMTS4 ACAN	1.63e-05	2	141	2	23897278
Pubmed	MMP proteolysis of the human extracellular matrix protein aggrecan is mainly a process of normal turnover.	ADAMTS4 ACAN	1.63e-05	2	141	2	22670872
Pubmed	Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation.	MCF2L CDC42	1.63e-05	2	141	2	12637522
Pubmed	Gene knockout analysis of two gamma-tubulin isoforms in mice.	TUBG2 TUBG1	1.63e-05	2	141	2	15893303
Pubmed	Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes.	PRKAR1A PRKAR1B	1.63e-05	2	141	2	8407966
Pubmed	Regulation and related mechanism of GSN mRNA level by hnRNPK in lung adenocarcinoma cells.	HNRNPK GSN	1.63e-05	2	141	2	30771276
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	FLNA DPYSL2 ANK3 TSPOAP1 TUBG1 SLC6A1 OXCT1 KCNA4 SLC16A1 PRKAR1A DYNC1LI1 PRKAR1B KCNAB1 EMC10 CDC42 PCK2	1.64e-05	1139	141	16	36417873
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	FLNA FLNC IMPDH2 E2F7 PRPF6 ACTL6A HNRNPK SF3B3 ZC3H4 PRKAR1A MOV10	1.65e-05	551	141	11	34728620
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	KRT8 IMPDH2 ANK3 CDK12 PKD1L2 HNRNPK SHROOM1 SLC35D3 MFSD10	1.78e-05	361	141	9	26167880
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SHROOM3 ANK3 DSCAM WDR7 EPB41L5 CEP192 AGPS PKHD1L1 HNRNPK STRIP1 ZC3H4 GLI3 CLSPN	1.80e-05	777	141	13	35844135
Pubmed	Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth.	ADAMTS4 ACAN GLI3	1.81e-05	13	141	3	32909945
Pubmed	Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling.	TUBG2 TUBG1 GLI3	1.81e-05	13	141	3	24853502
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	GAK DSCAM KRT79 HNRNPK SF3B3 SLC16A1 DMPK	1.97e-05	202	141	7	24639526
Pubmed	International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels.	KCNK1 KCNK10 KCNK6	2.30e-05	14	141	3	16382106
Pubmed	Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin.	FLNA GLI3 DCHS1	2.30e-05	14	141	3	32151560
Pubmed	Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.	LAMA1 LAMA5 GLI3	2.30e-05	14	141	3	19783738
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SOX4 WHRN ANK3 RHBDD2 PRPF6 NPHP4 TUBG1 GSN GPBP1L1 SF3B3 GLI3 PRKAR1A B9D1 DYNC1LI1 KATNIP PCK2 MOV10	2.69e-05	1321	141	17	27173435
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	IVD CSMD1 NOTCH4	2.86e-05	15	141	3	23583980
Pubmed	Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival.	TUBG2 TUBG1 ROM1	2.86e-05	15	141	3	21148103
Pubmed	Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.	WHRN LAMA5 ADGRV1 ACAN	3.10e-05	44	141	4	27534441
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	KRT8 LAMA1 LAMA5	3.51e-05	16	141	3	17601529
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNA FLNC DPYSL2 IMPDH2 CENPC EPB41L5 PRPF6 ACTL6A AGPS MIDEAS HNRNPK SF3B3 OXCT1 SLC16A1 DYNC1LI1 PCK2 MOV10	3.63e-05	1353	141	17	29467282
Pubmed	Primary Cilia are Required for Cell-Type Determination and Angiogenesis in Pituitary Development.	TUBG2 LHX3 TUBG1 FOXF1	4.03e-05	47	141	4	39001875
Pubmed	MicroRNA-140 plays dual roles in both cartilage development and homeostasis.	ADAMTS4 MEOX1 ACAN	4.25e-05	17	141	3	20466812
Pubmed	Pleckstrin homology domain-mediated activation of the rho-specific guanine nucleotide exchange factor Dbs by Rac1.	MCF2L CDC42	4.88e-05	3	141	2	14701795
Pubmed	[Replicative association analysis of genetic markers of cognitive traits with Alzheimer's disease in a Russian population].	CSMD1 NOTCH4	4.88e-05	3	141	2	25845235
Pubmed	Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma.	FLNC CDC42	4.88e-05	3	141	2	28031525
Pubmed	Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.	FLNA FLNC	4.88e-05	3	141	2	11038172
Pubmed	T cell activation triggers reversible inosine-5'-monophosphate dehydrogenase assembly.	IMPDH1 IMPDH2	4.88e-05	3	141	2	30154209
Pubmed	Heterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitro.	LAMA1 LAMA5	4.88e-05	3	141	2	10620696
Pubmed	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.	FLNA FLNC	4.88e-05	3	141	2	11102480
Pubmed	Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.	FLNA FLNC	4.88e-05	3	141	2	17825253
Pubmed	Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences.	LAMA1 LAMA5	4.88e-05	3	141	2	9006922
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNC	4.88e-05	3	141	2	12393796
Pubmed	Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells.	LAMA1 LAMA5	4.88e-05	3	141	2	12393739
Pubmed	α1- and α5-containing laminins regulate the development of bile ducts via β1 integrin signals.	LAMA1 LAMA5	4.88e-05	3	141	2	22761447
Pubmed	Exclusion of catalytic and regulatory subunits of cAMP-dependent protein kinase as candidate genes for the defect causing cystic fibrosis.	PRKAR1A PRKAR1B	4.88e-05	3	141	2	3479018
Pubmed	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.	FLNA FLNC	4.88e-05	3	141	2	9412467
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNC	4.88e-05	3	141	2	11153914
Interaction	FLNC interactions	IGSF8 FLNA FLNC DPYSL2 ANK3 CAPN3 NPHP4 PRKAR1A CDC42 FOXF1	5.30e-06	234	139	10	int:FLNC
GeneFamily	Potassium two pore domain channel subfamily K	KCNK1 KCNK10 KCNK6	6.70e-05	15	98	3	277
GeneFamily	Fibronectin type III domain containing\|USH2 complex	WHRN ADGRV1	1.73e-04	4	98	2	1244
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	GAK TNS1	7.97e-04	8	98	2	837
GeneFamily	PDZ domain containing	WHRN SHROOM3 FRMPD2 MAGI3 PDZD2	1.43e-03	152	98	5	1220
GeneFamily	Laminin subunits	LAMA1 LAMA5	1.85e-03	12	98	2	626
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	CEP192 PCIF1 KCNK10 CSMD1 TNS1	3.05e-03	181	98	5	694
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_DN	PRKD2 DPYSL2 IMPDH1 KRT79 PKHD1L1 GSN ABCA6 TNS1 ADAMTSL4 FOXF1 NOTCH4 SMAD7 PDZD2	2.67e-06	491	141	13	MM455
Coexpression	GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN	DPYSL2 GAK IMPDH1 WDR7 NBL1 NPHP4 PPIC PCK2	1.28e-05	199	141	8	M5251
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2	IGSF8 WHRN FLNA FLNC IMPDH1 IMPDH2 ADAMTS4 FKBP9 NBL1 PPIC IVD SLC7A3 TRPM5 TBRG1 HMCN1 NFATC4 DCHS1 PRKAR1B KCNK6 MOV10 OPLAH PDZD2	1.57e-05	1228	139	22	facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS4 F2RL3 LAMA5 GSN PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4 SMAD7	7.36e-10	196	141	10	c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	SHROOM3 ANK3 EPB41L5 LAMA5 MAGI3 ADGRV1 PLEKHG1 TNS1 PDZD2	3.87e-09	170	141	9	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	Control\|World / group, cell type (main and fine annotations)	SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 KCNK1 DMBT1 PDZD2	6.64e-08	168	141	8	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM3 ANK3 EPB41L5 MAGI3 TRIM71 ADGRV1 XKR6 RHOBTB2	1.45e-07	186	141	8	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	SOX4 KRT8 SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 KCNK1	1.45e-07	186	141	8	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F2RL3 LAMA5 MEOX1 PLEKHG1 CASKIN2 MCF2L RGL2 NOTCH4	1.58e-07	188	141	8	a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM3 ANK3 EPB41L5 MAGI3 TRIM71 ADGRV1 RHOBTB2 PDZD2	1.78e-07	191	141	8	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	SHROOM3 ANK3 DSCAM EPB41L5 LAMA5 MAGI3 TRIM71 ADGRV1	1.78e-07	191	141	8	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 XKR6 PDZD2	2.34e-07	198	141	8	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	IMPDH1 SOBP SLC6A1 PLEKHG1 SHROOM1 TNS1 NOTCH4 PDZD2	2.53e-07	200	141	8	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	IMPDH1 SOBP SLC6A1 PLEKHG1 SHROOM1 TNS1 NOTCH4 PDZD2	2.53e-07	200	141	8	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	IMPDH1 SOBP SLC6A1 PLEKHG1 SHROOM1 TNS1 NOTCH4 PDZD2	2.53e-07	200	141	8	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	IMPDH1 SOBP SLC6A1 PLEKHG1 SHROOM1 TNS1 NOTCH4 PDZD2	2.53e-07	200	141	8	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	IMPDH1 SOBP SLC6A1 PLEKHG1 SHROOM1 TNS1 NOTCH4 PDZD2	2.53e-07	200	141	8	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	IMPDH1 SOBP SLC6A1 PLEKHG1 SHROOM1 TNS1 NOTCH4 PDZD2	2.53e-07	200	141	8	7136936d05ab344a560cf159684c881063b5430d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	F2RL3 GSN CASKIN2 DCHS1 CLSPN FOXF1 NOTCH4	1.11e-06	168	141	7	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 ANK3 EPB41L5 LAMA5 MAGI3 ADGRV1 ACAN	1.20e-06	170	141	7	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel\|Adult / Lineage, Cell type, age group and donor	MEOX1 PLEKHG1 OXCT1 DCHS1 PRKAR1B MCF2L NOTCH4	1.30e-06	172	141	7	ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	SHROOM3 EPB41L5 LAMA5 MAGI3 ADGRV1 RHOBTB2 PDZD2	1.69e-06	179	141	7	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 ANK3 DSCAM EPB41L5 LAMA5 MAGI3 ADGRV1	1.69e-06	179	141	7	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYSL2 ADAMTS4 F2RL3 MCF2L FOXF1 NOTCH4 SMAD7	1.76e-06	180	141	7	efc4c5a4dea456527526bbfd88cf70d803893671
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYSL2 ADAMTS4 F2RL3 GSN MEOX1 FOXF1 NOTCH4	1.96e-06	183	141	7	858682df5592c6856487487a7baabd6e60e63a38
ToppCell	3'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DPYSL2 ADAMTS4 F2RL3 GSN MEOX1 FOXF1 NOTCH4	1.96e-06	183	141	7	f8212bf8a8b8312434ae030261c558c147f61747
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 ADGRV1 PKD1L2 PKHD1L1 KCNA4 HMCN1 CSMD1	2.03e-06	184	141	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	SHROOM3 ANK3 MAGI3 ADGRV1 RHOBTB2 DMBT1 PDZD2	2.03e-06	184	141	7	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 ADGRV1 PKD1L2 PKHD1L1 KCNA4 HMCN1 CSMD1	2.03e-06	184	141	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 ADGRV1 PKD1L2 PKHD1L1 KCNA4 HMCN1 CSMD1	2.03e-06	184	141	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 ANK3 EPB41L5 MAGI3 TRIM71 ADGRV1 PLEKHG1	2.11e-06	185	141	7	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GAK ADAMTS4 F2RL3 PLEKHG1 MCF2L TNS1 NOTCH4	2.11e-06	185	141	7	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	Endothelial-A-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	F2RL3 PLEKHG1 CASKIN2 DCHS1 MCF2L FOXF1 NOTCH4	2.18e-06	186	141	7	796cbae2a417502aaf0891fc9c382bbfd88967fe
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F2RL3 GSN MEOX1 PLEKHG1 CASKIN2 MCF2L NOTCH4	2.34e-06	188	141	7	0026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 RHOBTB2 PDZD2	2.34e-06	188	141	7	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Endothelial-A-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS4 F2RL3 PLEKHG1 CASKIN2 DCHS1 FOXF1 NOTCH4	2.34e-06	188	141	7	0824d567356d360fd8e78e840c30529c139f98a1
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ADAMTS4 LAMA5 PLEKHG1 KCNAB1 MCF2L NOTCH4 PDZD2	2.51e-06	190	141	7	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	LAM-Epithelial-AT1\|LAM / Condition, Lineage and Cell class	KRT8 SHROOM3 EPB41L5 LAMA5 MAGI3 PTPRU TNS1	2.60e-06	191	141	7	66875b2ec2c510489407f3e433a90cdf74a15094
ToppCell	Control-Epithelial-Club\|Control / Disease state, Lineage and Cell class	KRT8 SHROOM3 ANK3 EPB41L5 MAGI3 PTPRU KCNK1	2.69e-06	192	141	7	d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	SHROOM3 ANK3 MAGI3 ADGRV1 RHOBTB2 DMBT1 PDZD2	2.69e-06	192	141	7	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 RHOBTB2 PDZD2	2.69e-06	192	141	7	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 RHOBTB2 PDZD2	2.69e-06	192	141	7	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SHROOM3 ANK3 MAGI3 ADGRV1 RHOBTB2 KCNK1 DMBT1	2.79e-06	193	141	7	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA ADAMTS4 KCNA4 ACAN KCNAB1 TNS1 FOXF1	2.79e-06	193	141	7	7631bf3362b4fa061ffeab4879ab12c4708dc4c0
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA ADAMTS4 KCNA4 ACAN KCNAB1 TNS1 FOXF1	2.79e-06	193	141	7	8d15c63f2ae48d0a00d7ef5fdafa917ab8ad0571
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	2.79e-06	193	141	7	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SHROOM3 ANK3 MAGI3 ADGRV1 RHOBTB2 KCNK1 DMBT1	2.79e-06	193	141	7	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 RHOBTB2 PDZD2	2.89e-06	194	141	7	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 PLEKHG1 KCNA4	2.99e-06	195	141	7	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 SHROOM3 ANK3 MAGI3 ADGRV1 XKR6 PDZD2	3.09e-06	196	141	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	PND10-Mesenchymal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SOX4 FLNA FKBP9 PPIC GSN HMCN1 TNS1	3.09e-06	196	141	7	ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCell	Fetal_29-31_weeks-Endothelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	F2RL3 PKHD1L1 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.09e-06	196	141	7	3981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCell	Endothelial\|World / Lineage, Cell type, age group and donor	F2RL3 PKHD1L1 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.09e-06	196	141	7	96c6d78482a130ce4e29f6629972a06d10d7530e
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Endothelial-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ADAMTS4 LAMA5 PKHD1L1 MEOX1 PLEKHG1 MCF2L NOTCH4	3.19e-06	197	141	7	f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADAMTS4 LAMA5 PKHD1L1 MEOX1 PLEKHG1 MCF2L NOTCH4	3.19e-06	197	141	7	1a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCell	myeloid-pro-pDC\|World / Lineage and Cell class	SOX4 E2F7 SPNS3 GSN KCNK1 KCNK10 CLSPN	3.19e-06	197	141	7	8918ee006b16f6b86ed33ce1dd5c0f01f51f88f5
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADAMTS4 LAMA5 PKHD1L1 MEOX1 PLEKHG1 MCF2L NOTCH4	3.19e-06	197	141	7	96d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	FLNC SOBP FKBP9 NBL1 PPIC HMCN1 GLI3	3.30e-06	198	141	7	4f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Capillary\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.41e-06	199	141	7	3fea92affacd4c1f588fa81807df35d6c69b7241
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 RHOBTB2 PDZD2	3.41e-06	199	141	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS4 LAMA5 MEOX1 PLEKHG1 DCHS1 MCF2L SMAD7	3.41e-06	199	141	7	07bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Capillary-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.41e-06	199	141	7	993999adf346b4fd557989bc53c17eb0ccb996c9
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SHROOM3 ANK3 EPB41L5 MAGI3 ADGRV1 RHOBTB2 PDZD2	3.41e-06	199	141	7	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGSF8 DPYSL2 ANK3 ADAMTS4 CAPN3 GSN KCNK1	3.41e-06	199	141	7	214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCell	droplet-Trachea\|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOBP FKBP9 NBL1 PPIC GSN CEMIP ACAN	3.41e-06	199	141	7	1c7d30765ddb2291967da5d15664c6238c680c1d
ToppCell	droplet-Trachea\|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOBP FKBP9 NBL1 PPIC GSN CEMIP ACAN	3.41e-06	199	141	7	b9038a1ccf3ef3123e2e39afbe6213c363437443
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Capillary\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.41e-06	199	141	7	89f4db619fbed90f7fdf6ece7a671e514b5c6d76
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F2RL3 LAMA5 MEOX1 PLEKHG1 MCF2L NOTCH4 SMAD7	3.41e-06	199	141	7	258d59cf811bf1668ffbb5f18f961021f660de62
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	F2RL3 MIDEAS CASKIN2 MCF2L FOXF1 NOTCH4 SMAD7	3.41e-06	199	141	7	772b3f60b83e29b958e1e70dadfd9f058ed4cb7c
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_capillary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	2d962c9d63e9e5f1a06870e383609672e7b1738c
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	2989325b0e78ab42f362cfb59e34a4fce7f8e869
ToppCell	Parenchymal-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	F2RL3 PKHD1L1 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	0e648e9eb96c83a94505d07323785a7a40997eb0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGSF8 DPYSL2 ANK3 ADAMTS4 CAPN3 GSN KCNK1	3.53e-06	200	141	7	acdef0b9096c774040948fc75621ff2b08ea2ee8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGSF8 DPYSL2 ANK3 ADAMTS4 CAPN3 GSN KCNK1	3.53e-06	200	141	7	091a18d6efed81cab99955c3047f172170f70476
ToppCell	Lung_Parenchyma-Control-Endothelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	F2RL3 PKHD1L1 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	41ac6adbf61763aa8a81a0ed586c4a5542a42cc5
ToppCell	Biopsy_Other_PF-Epithelial-Transitional_AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	KRT8 SHROOM3 EPB41L5 LAMA5 MAGI3 RHOBTB2 KCNK1	3.53e-06	200	141	7	1ba6327851aa61e9a1f1fe1671bc27929d93ac74
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGSF8 DPYSL2 ANK3 ADAMTS4 CAPN3 GSN KCNK1	3.53e-06	200	141	7	3b8513defe25262ab4b492345b2628570eaefd17
ToppCell	distal-Endothelial-Capillary_Intermediate_1-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	43bc48413b100a06f8edd9acd812296788fcbf5b
ToppCell	Bronchial-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	F2RL3 PKHD1L1 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	F2RL3 PKHD1L1 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	5109b417c066ecca0252008206b4f4b7a14c8702
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	F2RL3 LAMA5 CASKIN2 MCF2L FOXF1 NOTCH4 SMAD7	3.53e-06	200	141	7	6567683f8f534310fecb44a6721909183fdc15ca
ToppCell	Biopsy_IPF-Endothelial\|Biopsy_IPF / Sample group, Lineage and Cell type	F2RL3 PKHD1L1 MEOX1 CASKIN2 DCHS1 FOXF1 NOTCH4	3.53e-06	200	141	7	7ccd3b617838b39da814278dc0e12384013401ce
ToppCell	distal-Endothelial-Capillary_Intermediate_1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	4d6714d48738cdee7d535923f6dd2431e5304741
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	F2RL3 LAMA5 PLEKHG1 CASKIN2 MCF2L FOXF1 NOTCH4	3.53e-06	200	141	7	6a3ccd0ea742fa76282c2b0fbc59942b4ef47bb8
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MEOX1 CASKIN2 ACAN DMRTB1 ADGRF3	9.99e-06	90	141	5	a0baaf2b3cf07d457f0d242fc213689cba6fd449
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MEOX1 CASKIN2 ACAN DMRTB1 ADGRF3	9.99e-06	90	141	5	ab4b08c6ac8695b38f841c0ecf2bb2c032111d04
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 ANK3 EPB41L5 LAMA5 MAGI3 ADGRV1	1.17e-05	159	141	6	8680b054622f573a82b1625fb93c2d5db81d1034
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NCOA2 WHRN ANK3 TSPOAP1 SPNS3 OXCT1	1.21e-05	160	141	6	8aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PADI4 COL20A1 ACAN DMRTB1 KLK13	1.67e-05	100	141	5	3a7e5469de88745ac455c35deeb859d68dce73fa
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PADI4 COL20A1 ACAN DMRTB1 KLK13	1.67e-05	100	141	5	187e31d4186b82a37569b98d83e4813017cc2ddd
ToppCell	mild_COVID-19-pDC\|World / disease group, cell group and cell class (v2)	SOX4 SPNS3 HMCN1 NFATC4 KCNK1 KCNK10	1.83e-05	172	141	6	dab2f1a05c7df58d9387b13271b3f1f1583f9ac3
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC DPYSL2 KRT8 NBL1 GSN DMPK	1.95e-05	174	141	6	68a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCell	droplet-Fat-Bat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 TUBG2 MEOX1 NFATC4 KCNAB1 CSMD1	2.02e-05	175	141	6	b4f01e7782cdd107d0817ef601891fd3a382bc35
ToppCell	droplet-Fat-Bat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 TUBG2 MEOX1 NFATC4 KCNAB1 CSMD1	2.02e-05	175	141	6	ef6f811d8e1839f405c3b41090ddf79be57a099f
ToppCell	droplet-Fat-Bat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAALAD2 TUBG2 MEOX1 NFATC4 KCNAB1 CSMD1	2.02e-05	175	141	6	7f7598d46d10bff1cbea42f950bdde1aaa16e9a4
ToppCell	Endothelial-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	FLNC ADAMTS4 F2RL3 PKHD1L1 PLEKHG1 DCHS1	2.08e-05	176	141	6	b288116a4588a1f9db9d49af92cea118937c9201
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERMP1 ACVR1C KRT79 NPHP4 CLSPN RUFY4	2.22e-05	178	141	6	de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GAK ADAMTS4 F2RL3 PLEKHG1 MCF2L NOTCH4	2.29e-05	179	141	6	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WHRN ANK3 TCN1 LAMA5 SHROOM1 KCNK1	2.29e-05	179	141	6	ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WHRN ANK3 TCN1 LAMA5 SHROOM1 KCNK1	2.29e-05	179	141	6	c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GAK F2RL3 PLEKHG1 MCF2L TNS1 NOTCH4	2.36e-05	180	141	6	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	SHROOM3 ANK3 MAGI3 ADGRV1 RHOBTB2 DMBT1	2.36e-05	180	141	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	F2RL3 LAMA5 PLEKHG1 MCF2L FOXF1 NOTCH4	2.44e-05	181	141	6	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
Disease	complex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)	TUBG2 TUBG1	2.05e-05	2	134	2	DOID:0090138 (implicated_via_orthology)
Disease	glycine measurement	CAPN3 EFCAB13 ERMP1 ADGRV1 PKD1L2 MSL2	3.96e-05	137	134	6	EFO_0009767
Disease	chenodeoxycholate measurement	HMCN1 KCNK10 SMAD7	4.00e-05	15	134	3	EFO_0010471
Disease	Disorder of eye	WHRN IMPDH1 RBP3 PRPF6 ADGRV1 NPHP4 ROM1	5.43e-05	212	134	7	C0015397
Disease	alkaline phosphatase measurement	NCOA2 WHRN PRKD2 ERMP1 XKR6 ACVR1C GSN ABCA6 NFATC4 GLI3 PCIF1 PRKAR1A DMBT1 CDC42 SMAD7	6.07e-05	1015	134	15	EFO_0004533
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNC	6.12e-05	3	134	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNC	6.12e-05	3	134	2	DOID:0111190 (implicated_via_orthology)
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	SHROOM3 CAPN3 XKR6 MSL2 ABCA6 PCIF1	6.56e-05	150	134	6	EFO_0004611, EFO_0020947
Disease	coronary artery disease	PRKD2 SHROOM3 DSCAM CDK12 EFCAB13 MAGI3 SPNS3 PTPRU MSL2 PLEKHG1 SF3B3 PRKAR1A KCNAB1 MCF2L TNS1 SMAD7	1.07e-04	1194	134	16	EFO_0001645
Disease	cortical surface area measurement	NCOA2 PRKD2 DPYSL2 SHROOM3 ANK3 NBL1 TRIM71 ADGRV1 XKR6 STRIP1 TBC1D16 PLEKHG1 GLI3 KCNK10 TNS1 MOV10 PDZD2	1.31e-04	1345	134	17	EFO_0010736
Disease	Ciliopathies	WHRN IMPDH1 ADGRV1 NPHP4 B9D1	1.50e-04	110	134	5	C4277690
Disease	vital capacity	SHROOM3 CDK12 NBL1 TRIM71 LHX3 AGPS IVD SLC6A1 HMCN1 NFATC4 ACAN GLI3 ROM1 TNS1 MOV10 PDZD2	1.59e-04	1236	134	16	EFO_0004312
Disease	uterine fibroid	NCOA2 SLC7A3 KCNAB1 CSMD1 CDC42 TNS1	3.06e-04	199	134	6	EFO_0000731
Disease	Retinitis pigmentosa	IMPDH1 RBP3 PRPF6 ROM1	3.66e-04	74	134	4	cv:C0035334
Disease	Colorectal Carcinoma	FLNC DPYSL2 FRMPD2 LAMA1 RBP3 SPNS3 PTPRU ABCA6 GLI3 DCHS1 SMAD7	3.73e-04	702	134	11	C0009402
Disease	basophil count	PADI4 NAALAD2 TSPOAP1 CAPN3 RHBDD2 XKR6 UPK3A NOTCH4 RUFY4	3.76e-04	483	134	9	EFO_0005090
Disease	non-small cell lung carcinoma	NCOA2 DSCAM LAMA1 ADGRF3	3.85e-04	75	134	4	EFO_0003060
Disease	Disproportionate short stature	FLNA ACAN GLI3 PRKAR1A	4.26e-04	77	134	4	C0878659
Disease	cortical thickness	NCOA2 DPYSL2 SHROOM3 LAMA1 NBL1 ADGRV1 XKR6 SPNS3 PLEKHG1 GLI3 B9D1 KLHL8 TNS1 PDZD2	5.55e-04	1113	134	14	EFO_0004840
Disease	Meckel syndrome (implicated_via_orthology)	NPHP4 B9D1	5.63e-04	8	134	2	DOID:0050778 (implicated_via_orthology)
Disease	creatinine measurement	PRKD2 SHROOM3 IMPDH2 DSCAM CDK12 EPB41L5 LAMA5 LHX3 ADGRV1 CEMIP TBC1D10B OPLAH SMAD7	6.20e-04	995	134	13	EFO_0004518
Disease	free cholesterol:total lipids ratio, intermediate density lipoprotein measurement	CAPN3 XKR6 PCIF1 KLHL8	6.47e-04	86	134	4	EFO_0008595, EFO_0020945
Disease	red blood cell density measurement	SHROOM3 CDK12 FKBP9 EPB41L5 LHX3 ADGRV1 KCNA4 ZC3H4 PCIF1 PRKAR1B KLHL8 SMAD7	6.96e-04	880	134	12	EFO_0007978
Disease	hematocrit	SHROOM3 EPB41L5 ADGRV1 GSN PLEKHG1 KCNA4 ABCA6 ZC3H4 PRKAR1B EMC10 DMBT1 NOTCH4 SMAD7	7.19e-04	1011	134	13	EFO_0004348
Disease	nephronophthisis (implicated_via_orthology)	NPHP4 B9D1	7.22e-04	9	134	2	DOID:12712 (implicated_via_orthology)
Disease	mitral valve prolapse (is_implicated_in)	FLNA DCHS1	7.22e-04	9	134	2	DOID:988 (is_implicated_in)
Disease	Anorectal Malformations	SOX4 GLI3 FOXF1	8.60e-04	41	134	3	C3495676
Disease	aspartate aminotransferase measurement	WHRN PRKD2 KRT8 SHROOM3 XKR6 KRT79 MSL2 RHOBTB2 KLHL8 CSMD1 MOV10 NOTCH4	8.79e-04	904	134	12	EFO_0004736
Disease	Kunitz-type protease inhibitor 2 measurement	KCNK6 CATSPERG	8.99e-04	10	134	2	EFO_0008200
Disease	RETINITIS PIGMENTOSA	RBP3 ROM1	8.99e-04	10	134	2	268000
Disease	plasma trimethylamine N-oxide measurement	FIG4 RHOBTB2	8.99e-04	10	134	2	EFO_0005691
Disease	forced expiratory volume	DSCAM CDK12 NBL1 TRIM71 LHX3 IVD SLC6A1 FIG4 NFATC4 ACAN TNS1	9.75e-04	789	134	11	EFO_0004314
Disease	degenerative disc disease (biomarker_via_orthology)	ADAMTS4 ACAN	1.10e-03	11	134	2	DOID:90 (biomarker_via_orthology)
Disease	myocardial infarction	SHROOM3 MAGI3 PLEKHG1 DMBT1 TNS1 SMAD7 PDZD2	1.13e-03	350	134	7	EFO_0000612
Disease	Gastrointestinal Stromal Sarcoma	GLI3 B9D1 FOXF1	1.28e-03	47	134	3	C3179349
Disease	triacylglycerol 44:1 measurement	DSCAM CSMD1	1.31e-03	12	134	2	EFO_0010399
Disease	Retinitis Pigmentosa	IMPDH1 RBP3 PRPF6 ROM1	1.32e-03	104	134	4	C0035334
Disease	phospholipids in medium LDL measurement	EFCAB13 ABCA6 PCIF1	1.45e-03	49	134	3	EFO_0022183
Disease	cholesterol in medium LDL measurement	EFCAB13 ABCA6 PCIF1	1.45e-03	49	134	3	EFO_0022224
Disease	Gastrointestinal Stromal Tumors	GLI3 B9D1 FOXF1	1.54e-03	50	134	3	C0238198
Disease	serum albumin measurement	SHROOM3 CDK12 CAPN3 EPB41L5 ADGRV1 TEX35 MSL2 ABCA6 NOTCH4	1.57e-03	592	134	9	EFO_0004535
Disease	total lipids in medium LDL	EFCAB13 ABCA6 PCIF1	1.72e-03	52	134	3	EFO_0022180
Disease	response to olanzapine	IGSF8 ADGRV1	2.07e-03	15	134	2	GO_0097333
Disease	urate measurement, bone density	DSCAM WDR7 LAMA5 MAGI3 RHOBTB2 PRKAR1B DMBT1 NOTCH4 PDZD2	2.13e-03	619	134	9	EFO_0003923, EFO_0004531
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	SHROOM3 CAPN3 XKR6 ABCA6 PCIF1	2.24e-03	200	134	5	EFO_0004611, EFO_0020945
Disease	phospholipids in LDL measurement	EFCAB13 ABCA6 PCIF1	2.35e-03	58	134	3	EFO_0022294
Disease	glycochenodeoxycholate measurement	IMPDH1 CEMIP	2.66e-03	17	134	2	EFO_0010490
Disease	1-Methylhistidine measurement	NCOA2 CDK12	2.66e-03	17	134	2	EFO_0021543
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	SHROOM3 XKR6 ABCA6 PCIF1	2.73e-03	127	134	4	EFO_0008595, EFO_0020947
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	CAPN3 HNRNPK MSL2 ABCA6 PCIF1 KLHL8	2.85e-03	307	134	6	EFO_0004612, EFO_0020946
Disease	Tinnitus	SOX4 E2F7 XKR6 KRT79	2.97e-03	130	134	4	HP_0000360
Disease	age at onset, smoking initiation	NCOA2 EMC10	3.33e-03	19	134	2	EFO_0004847, EFO_0005670
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	SHROOM3 CAPN3 ABCA6 PCIF1 KLHL8	3.51e-03	222	134	5	EFO_0008317, EFO_0020943
Disease	interstitial lung disease	IVD CSMD1 NOTCH4	3.55e-03	67	134	3	EFO_0004244
Disease	Abnormality of refraction	ANK3 DSCAM CDK12 FRMPD2 LHX3 SLC6A1 KCNA4 SLC16A1 GLI3	3.70e-03	673	134	9	HP_0000539
Disease	refractive error	ANK3 FRMPD2 XKR6 AGPS KCNA4 SLC16A1	3.83e-03	326	134	6	MONDO_0004892
Disease	rheumatoid arthritis (is_marker_for)	ADAMTS4 ACAN NOTCH4	3.86e-03	69	134	3	DOID:7148 (is_marker_for)
Disease	Joubert syndrome 1	B9D1 KATNIP	4.06e-03	21	134	2	C4551568
Disease	bilirubin measurement	KRT8 PKD1L2 ACVR1C KCNA4 ROM1 DMBT1 KLHL8	4.16e-03	442	134	7	EFO_0004570

Protein segments in the cluster

Peptide	Gene	Start	Entry
SFQGSYVLLVVGGGP	CATSPERG	941	Q6ZRH7
GQGLGDSLYATPGLV	ADGRF3	671	Q8IZF5
TDYSNLGPVGGGTSG	CDX4	111	O14627
KLQNYGELGPGTTGA	CDK12	1436	Q9NYV4
LVSGNLTDRGGPLGY	ADAMTSL4	486	Q6UY14
GGQYTGSEGVVLSPN	CSMD1	1626	Q96PZ7
NTLVGEAGGGLIDYP	BPIFB4	381	P59827
YPTLVGLAGGTTSAA	ARSI	351	Q5FYB1
GTDGLSYNGAIIVSG	ABCA6	941	Q8N139
RPGLYGSVIVAGGNT	ACTL6A	341	O96019
IYDVTASGSGSGLPL	ACVR1C	171	Q8NER5
ATFPSSGGYGQGSLI	ADGRV1	6236	Q8WXG9
SYITGETVVVGGGTP	DHRS4	261	Q9BTZ2
NGIGLTLASGGTFPY	CEMIP	811	Q8WUJ3
SLGNGTPVTSKGGDY	ERMP1	816	Q7Z2K6
GLYTGEVTEIVGGPG	RAD51D	96	O75771
GYLSPDILLEGSGNG	TSPOAP1	1706	O95153
TTGGPGDDYGVLGST	MEOX1	126	P50221
VLNTNGTSGFLPGGY	KLK13	26	Q9UKR3
GGLSSAYGGLTSPGL	KRT8	421	P05787
SLSTIGLGDYVPGEA	KCNK6	211	Q9Y257
YVTRGPQTGGISGLD	PADI4	391	Q9UM07
SSVVAGYGSPGQKGT	MFSD10	381	Q14728
GGGPISSILVNKYGS	SLC16A1	71	P53985
EGENGTILYTLTGPG	DCHS1	1246	Q96JQ0
GVGALTYTLVGGADP	DCHS1	1361	Q96JQ0
GGTNGPITYSILSGN	DCHS1	2096	Q96JQ0
RSGPAGGYQTLGENS	GLI3	1206	P10071
YVGIGLPGLSFGSEG	TRIM71	586	Q2Q1W2
LGGDGPDQSIYIGAI	MAGI3	741	Q5TCQ9
GTVVYGEPITASLGT	DPYSL2	271	Q16555
VSKGAYAGITGNPSG	GPBP1L1	81	Q9HC44
QPGLSRGQDGYSGET	KATNIP	946	O60303
GIISGKYGNGVPESS	KCNAB1	301	Q14722
ISGGTSYVPDDGLTA	IMPDH2	6	P12268
GYSTVKGGPVSAGTS	KRT79	506	Q5XKE5
STTGYGHTVPLSDGG	KCNK1	116	O00180
GLSSTYTGGPLGNEI	DYNC1LI1	16	Q9Y6G9
PDQREIISFGSGYGG	PCK2	241	Q16822
LGGPIYAIGGLDDNT	KLHL8	411	Q9P2G9
GGLPSLANGQGIYSV	PDZD2	2266	O15018
YGGLGLSIEGPSKVD	FLNC	2071	Q14315
GLVSAYGPGLEGGTT	FLNC	2506	Q14315
YGPGLEGGTTGVSSE	FLNC	2511	Q14315
EGEGGKAQSSLGYIP	PRKD2	366	Q9BZL6
GLYGSLGEPTQALGR	LHX3	271	Q9UBR4
TTIGYGNIAPSTEGG	KCNK10	166	P57789
IGGEPYTLGLFDTAG	CDC42	46	P60953
LGGLPESGTIYNFSG	LAMA5	3246	O15230
GLSVYVQGEDGPGSQ	NBL1	131	P41271
GVLGITAPVQYGGSG	IVD	91	P26440
IGSSVINGLPTYNGL	MSL2	186	Q9HCI7
EGPVGSTLGSYATLT	CASKIN2	816	Q8WXE0
EILQAVGGGPGTGSY	DMPK	241	Q09013
KQYGLGPNGGIVTSL	GPN1	81	Q9HCN4
VGGGETYTIGLQFAP	NPHP4	1381	O75161
GQPGISGEASGVLYG	ACAN	1761	P16112
GGGYVVPLGTDRQST	PKD1L2	2101	Q7Z442
GADGSLYVVSPGGEE	HMCN1	1031	Q96RW7
ISGGTGYVPEDGLTA	IMPDH1	6	P20839
TLGVYVRVNGGPLGS	PTPRU	116	Q92729
QTPSVYDESGSTGGG	F2RL3	21	Q96RI0
YGEEGRGNIPGSAVL	FKBP9	341	O95302
SPITELLEQNGGYGS	GAK	326	O14976
GAEPGTYLTGTINGD	ADAMTS4	121	O75173
DGNDYSLGLTPTGVL	EPB41L5	241	Q9HCM4
QLDTEGVGSLGPGYE	IGSF8	361	Q969P0
VGLYEGTGLQGSLPV	PCIF1	481	Q9H4Z3
QGSGGYSLEIGSLAA	E2F7	436	Q96AV8
IDYQGRPSGGFVISG	CENPC	756	Q03188
SRSQYQGGGLVSEPG	DMRTB1	241	Q96MA1
VTCLYPGGGSSTLTG	COL20A1	626	Q9P218
TQGGSGVFGICSEPY	FIG4	211	Q92562
GYGGLSLSIEGPSKV	FLNA	2076	P21333
GFSVTGGINTSVPYG	FRMPD2	961	Q68DX3
GASLEGSQVYLGLSP	AVL9	166	Q8NBF6
SGEGVSNGYKGDTTP	ANK3	1226	Q12955
GGVGSSNVGVQEPYS	EFCAB13	371	Q8IY85
AYLSGGRGQDGSPVI	MCF2L	81	O15068
YLGHEGPGGAVSTSQ	MIDEAS	46	Q6PJG2
FTIPLSGYGGTSNLI	CEP192	1871	Q8TEP8
EGGSFGELALIYGTP	PRKAR1A	196	P10644
EGGSFGELALIYGTP	PRKAR1B	196	P31321
IYKGGTSREGGQTAP	GSN	546	P06396
PGALDGLEAGGYVSS	EMC10	116	Q5UCC4
LGYDTGPSDTQGVLG	B9D1	181	Q9UPM9
ATEAGGGNPSGIYSA	CAPN3	31	P20807
LGNAYFGSGSGPITL	DMBT1	1936	Q9UGM3
SQAPYGTLGAVSGGE	PPRC1	36	Q5VV67
LNDTYSLGPLGSGGF	SLC7A3	231	Q8WY07
GTATLENGSGPGLYV	ODF3L2	36	Q3SX64
PGDNGGSSIRGYILQ	DSCAM	1401	O60469
LPDTYGFQGSAGGLS	FOXF1	166	Q12946
LDGNTEPGLTLGGYF	GTF2H2C;	276	Q6P1K8
SGSRGGGVVPYLGTF	RGL2	421	O15211
AGAGDLTGDPIGYVT	SLC35D3	146	Q5M8T2
VYLFGGLGTSSSPVG	SOX4	296	Q06945
ECSLGQYTSIGGLGV	SLC6A1	101	P30531
GTGGVSIYGETFPDE	PPIC	106	P45877
LEGSGSYNKGSGVPD	IGLV4-60	71	A0A075B6I1
GGYSSGFRDSVPIQG	NFATC4	861	Q14934
PGESGSEGAGTFYIA	MOV10	221	Q9HCE1
GYVPGLGRGATGFTT	PRPF6	16	O94906
VLSGPAGGVVGYSAT	OPLAH	286	O14841
GRGSYGDLGGPIITT	HNRNPK	376	P61978
SNLYVGGIPEGEGTS	LAMA1	2621	P25391
TSDGILRGNGTGYLP	RHOBTB2	366	Q9BYZ6
ILQGYGDGQGPVTDT	RUFY4	21	Q6ZNE9
GYTLGSDTNTVVGLP	STRIP1	446	Q5VSL9
TGAQGAGVELYPGSI	SHCBP1L	526	Q9BZQ2
PYGTGLGQRTGQVTV	SHROOM1	421	Q2M3G4
SSLELGRGTQEGYPG	SHROOM3	676	Q8TF72
GLGIYITGVDPGSEA	WHRN	301	Q9P202
GGQVLSEYTGPTSAD	RNF169	486	Q8NCN4
YTPTGYGTLVQEGGS	OXCT1	156	P55809
LYNGSCSETTGLGGP	NOTCH4	1141	Q99466
CIIPIGGGTSVSYGL	AGPS	231	O00116
GQGSYETIGPLSEGD	CLSPN	31	Q9HAW4
FGLYGEPSEGTTGQA	NCOA2	586	Q15596
QDYTGGGLGAVEGLT	XKR6	186	Q5GH73
SSAETGGTNYLAPGG	SMAD7	231	O15105
GGTNYLAPGGLSDSQ	SMAD7	236	O15105
PTAGGALSVGIYQVG	RBP3	871	P10745
QRAGYGGTGSIEIPV	TRPM5	211	Q9NZQ8
GDAGSPYLTGLISSV	SPNS3	416	Q6ZMD2
DAGGETQGYLFPSGL	ROM1	301	Q03395
IAGGTGSGLGSYLLE	TUBG1	141	P23258
LDGNTEPGLTLGGYF	GTF2H2	276	Q13888
GYSGLATGNGLSDSP	SOBP	101	A7XYQ1
TVYSGALGTPGAAGS	RHBDD2	341	Q6NTF9
GSGSPSVLDGEIIYS	TBC1D16	26	Q8TBP0
SLDGVTNTSEGGYPE	TNS1	521	Q9HBL0
SGGEPLSQGAGSYVV	TCN1	406	P20061
GSTFLQTEGGRTGPY	UPK3A	86	O75631
GGSQYSGSLESSIPV	TBC1D10B	311	Q4KMP7
GTTLVITGNGFYPGN	PKHD1L1	1846	Q86WI1
PGGSESLVYTTLSGG	SF3B3	1111	Q15393
GGGQSSVLSGISLYD	ZC3H4	1136	Q9UPT8
IAGGTGSGLGSYLLE	TUBG2	141	Q9NRH3
GSLYAQTDGTLSGGE	PLEKHG1	711	Q9ULL1
GNIPSEASGLYKGGE	TEX35	196	Q5T0J7
IPEGFGLTSGGSNYS	WDR7	1156	Q9Y4E6
YGVASSVGTIQGAGP	TBRG1	106	Q3YBR2
SPVLSGGYVLGGGAI	UBE2Q1	336	Q7Z7E8
ETYGNLVSLGVGPAG	ZNF34	66	Q8IZ26
LDGQTEGTGAISGYP	USF1	71	P22415
LLPQDEGGGGYSSVR	KCNA4	156	P22459
GALNVSYSIGPGFTG	NAALAD2	311	Q9Y3Q0