Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	uridylyltransferase activity	TUT4 UAP1L1	3.04e-04	7	77	2	GO:0070569
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1D CACNA1E	5.19e-04	9	77	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1D CACNA1E	5.19e-04	9	77	2	GO:0099626
Domain	VDCC_a1su_IQ	CACNA1D CACNA1E	3.12e-04	7	73	2	IPR014873
Domain	GPHH	CACNA1D CACNA1E	3.12e-04	7	73	2	PF16905
Domain	GPHH_dom	CACNA1D CACNA1E	3.12e-04	7	73	2	IPR031649
Domain	Ca_chan_IQ	CACNA1D CACNA1E	3.12e-04	7	73	2	SM01062
Domain	Ca_chan_IQ	CACNA1D CACNA1E	3.12e-04	7	73	2	PF08763
Domain	VDCCAlpha1	CACNA1D CACNA1E	6.64e-04	10	73	2	IPR002077
Domain	Ubiquitin-rel_dom	RASIP1 PTPN13 PIK3C2B TP53BP2 USP47	7.68e-04	184	73	5	IPR029071
Domain	PI3/4_kinase_CS	PIK3C2B PRKDC	1.53e-03	15	73	2	IPR018936
Domain	CBS	IMPDH2 CLCN6	1.75e-03	16	73	2	SM00116
Domain	-	PIK3C2B PRKDC	1.75e-03	16	73	2	1.10.1070.11
Domain	PI3Kc	PIK3C2B PRKDC	1.75e-03	16	73	2	SM00146
Domain	PI3/4_kinase_cat_dom	PIK3C2B PRKDC	2.21e-03	18	73	2	IPR000403
Domain	PI3_PI4_kinase	PIK3C2B PRKDC	2.21e-03	18	73	2	PF00454
Domain	PI3_4_KINASE_3	PIK3C2B PRKDC	2.21e-03	18	73	2	PS50290
Domain	PI3_4_KINASE_1	PIK3C2B PRKDC	2.21e-03	18	73	2	PS00915
Domain	PI3_4_KINASE_2	PIK3C2B PRKDC	2.21e-03	18	73	2	PS00916
Domain	CBS_dom	IMPDH2 CLCN6	2.74e-03	20	73	2	IPR000644
Domain	CBS	IMPDH2 CLCN6	2.74e-03	20	73	2	PF00571
Domain	CBS	IMPDH2 CLCN6	2.74e-03	20	73	2	PS51371
Domain	Pentatricopeptide_repeat	PRKDC XAB2	3.61e-03	23	73	2	IPR002885
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	KNTC1 IMPDH2 ACACA KIF15 MAT2A UBAP1 MACF1 PSMD2 INTS9 AKAP10 PRKDC NUDCD1 PLOD1 TBC1D17 USP47 NPM3 XPOT	1.52e-08	1455	77	17	22863883
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	IMPDH2 ACACA MAT2A MYO19 MACF1 PSMD2 AKAP10 CHD4 PRKDC PLOD1 RASAL2 PHLDB2 TP53BP2 NPM3 XPOT	2.39e-07	1353	77	15	29467282
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PTPN13 SLC4A7 ACACA PIK3C2B DTNA MACF1 RASAL2 PHLDB2 C2CD5	4.00e-07	421	77	9	36976175
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	LUC7L PTPN13 SLC4A7 ACACA PIK3C2B SIK2 MACF1 PDCL STIL RASAL2 PHLDB2 TP53BP2	4.13e-07	861	77	12	36931259
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	KNTC1 PTPN13 PRKDC PLOD1 RASAL2 PHLDB2 TP53BP2 C2CD5 NIN	6.46e-07	446	77	9	24255178
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IMPDH2 ACACA MACF1 PSMD2 CHD4 PRKDC PLOD1 XAB2 USP47 XPOT	1.80e-06	653	77	10	22586326
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ACACA BRCA2 UBAP1 AZI2 PDCL STIL FHIP2A PLOD1 TP53BP2 USP47 NIN	2.77e-06	853	77	11	28718761
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PTPN13 MAT2A NGEF MACF1 PSMD2 NBEA CHD4 PRKDC UAP1L1 XAB2 RASAL2 USP47 XPOT	4.59e-06	1285	77	13	35914814
Pubmed	Structure and functional characterization of neuronal alpha 1E calcium channel subtypes.	CACNA1D CACNA1E	4.84e-06	2	77	2	8071363
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	PTPN13 ACACA MACF1 PDCL RASAL2 TP53BP2	7.28e-06	209	77	6	36779422
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	PTPN13 SLC4A7 IMPDH2 MACF1 PSMD2 CHD4 PRKDC	7.54e-06	322	77	7	26514267
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1E IMPDH2 KIF15 ZNF618 NGEF MACF1 NBEA CHD4 RASAL2 PHLDB2 TP53BP2	8.74e-06	963	77	11	28671696
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	LUC7L SLC4A7 IMPDH2 ACACA MAT2A MACF1 PSMD2 CHD4 PRKDC PLOD1 XAB2 NPM3 XPOT	1.29e-05	1415	77	13	28515276
Pubmed	No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers.	CDKN1B BRCA2	1.45e-05	3	77	2	18543099
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PTPN13 SLC4A7 IMPDH2 DTNA SIK2 MACF1 PDCL PLOD1 RASAL2 TBC1D17 C2CD5 NOL8 NIN	2.17e-05	1487	77	13	33957083
Pubmed	PSMD2 regulates breast cancer cell proliferation and cell cycle progression by modulating p21 and p27 proteasomal degradation.	CDKN1B PSMD2	2.89e-05	4	77	2	29777785
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	PTPN13 PIK3C2B STIL TP53BP2 C2CD5	3.80e-05	169	77	5	31462741
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KNTC1 KIF15 BRCA2 PIK3C2B DTNA CDK11A MACF1 NIN	4.81e-05	588	77	8	38580884
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1D CACNA1E	4.82e-05	5	77	2	15451373
Pubmed	Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.	CACNA1D CACNA1E	4.82e-05	5	77	2	12060068
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1D CACNA1E	4.82e-05	5	77	2	11296258
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	CDKN1B ACACA ZNF618 CDK11A PRKDC RASAL2 C2CD5	4.94e-05	432	77	7	23455922
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	FCSK IMPDH2 ACACA BRCA2 MYO19 INTS9 PLOD1 XPOT	5.94e-05	606	77	8	36538041
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	IMPDH2 ACACA PSMD2 CHD4 PRKDC NUDCD1 PLOD1 XAB2 NPM3 NOL8	6.46e-05	989	77	10	36424410
Pubmed	p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.	CDKN1B BRCA2	7.22e-05	6	77	2	16951165
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	KNTC1 IMPDH2 ACACA PRKDC PARP14	8.85e-05	202	77	5	33005030
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	KLHL2 KIF15 PIK3C2B UBAP1 MACF1 PSMD2 USP47	9.67e-05	481	77	7	28190767
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	MACF1 CHD4 PRKDC PDCL PARP14 TP53BP2	9.70e-05	332	77	6	37433992
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	LUC7L MAT2A CHD4 PRKDC NUDCD1 NPM3 NOL8	9.92e-05	483	77	7	36912080
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	LUC7L ACACA PSMD2 PRKDC PLOD1 XAB2 C2CD5 XPOT	9.97e-05	653	77	8	33742100
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1D CACNA1E	1.01e-04	7	77	2	12900400
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACACA KIF15 PIK3C2B CDK11A NBEA PLOD1 XPOT	1.18e-04	497	77	7	36774506
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNA1E NGEF MACF1 PSMD2 NBEA C2CD5	1.23e-04	347	77	6	17114649
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1D CACNA1E	1.34e-04	8	77	2	28330839
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	LUC7L IMPDH2 ACACA MAT2A PSMD2 CHD4 PRKDC PLOD1 XAB2 NPM3 XPOT	1.50e-04	1318	77	11	30463901
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	TMOD4 CDK11A PSMD2 NUDCD1 PDCL KLHL26	1.58e-04	363	77	6	25036637
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	PTPN13 IMPDH2 DTNA MAT2A MACF1 PSMD2 PRKDC RASAL2	1.73e-04	708	77	8	39231216
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FCSK TUT4 ZNF618 MACF1 CHD4 PDCL PHLDB2 C2CD5 NPM3 NIN	1.74e-04	1116	77	10	31753913
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	IMPDH2 MAT2A MACF1 PSMD2 CHD4 PRKDC NUDCD1 PARP14	1.78e-04	711	77	8	33022573
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	LUC7L IMPDH2 ACACA MAT2A PSMD2 CHD4 PRKDC NUDCD1 PLOD1 XAB2 PHLDB2	2.05e-04	1367	77	11	32687490
Pubmed	Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice.	CDKN1B BRCA2	2.15e-04	10	77	2	20484223
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	PTPN13 IMPDH2 ACACA MACF1 CHD4 PRKDC XAB2 TP53BP2 NOL8	2.20e-04	934	77	9	33916271
Pubmed	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.	BRCA2 PSMD2 INTS9	2.39e-04	54	77	3	16239144
Pubmed	A Hypoxia-Induced SCFFBXL1 E3 Ligase Ubiquitinates and Degrades the MEN1 Tumor Suppressor to Promote Colorectal Cancer Tumorigenesis.	CDKN1B UBAP1 PRKDC	2.52e-04	55	77	3	34237211
Pubmed	Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.	CDKN1B BRCA2 TP53BP2	2.52e-04	55	77	3	19536092
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	SLC4A7 PRKDC RASAL2 PHLDB2 TP53BP2	2.62e-04	255	77	5	15324660
Pubmed	FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.	BRCA2 PRKDC	2.63e-04	11	77	2	18406329
Pubmed	Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.	IMPDH2 MAT2A PSMD2 PRKDC PLOD1	2.67e-04	256	77	5	35777956
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	CDKN1B KNTC1 KIF15 MTSS1 CHD4	2.71e-04	257	77	5	30945288
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KNTC1 IMPDH2 ACACA MAT2A PSMD2 CHD4 PRKDC RASAL2 NPM3 XPOT MCOLN2	2.93e-04	1425	77	11	30948266
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	IMPDH2 MAT2A PSMD2 PRKDC PLOD1 XPOT	2.95e-04	408	77	6	33766124
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DTNA MAT2A PSMD2 AKAP10 PRKDC PLOD1 USP47 C2CD5 XPOT	3.00e-04	974	77	9	28675297
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CDKN1B ACACA CDK11A CHD4 PRKDC PHLDB2 USP47 C2CD5	3.16e-04	774	77	8	15302935
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	KNTC1 LUC7L IMPDH2 MYO19 PSMD2 CHD4 PRKDC FHIP2A PLOD1 NPM3 XPOT	3.21e-04	1440	77	11	30833792
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PTPN13 SLC4A7 ACACA NBEA CHD4 PRKDC RASAL2 NOL8	3.24e-04	777	77	8	35844135
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	PTPN13 ACACA KIF15 BRCA2 CHD4 TP53BP2	3.36e-04	418	77	6	34709266
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CACNA1E MACF1 NBEA RASAL2 TP53BP2	4.08e-04	281	77	5	28706196
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	MAT2A PSMD2 PRKDC USP47	4.09e-04	156	77	4	22952844
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	LUC7L TUT4 PTPN13 ACACA DTNA NGEF MACF1 ZNF236 PLOD1 DNAH14 KLHL26	4.25e-04	1489	77	11	28611215
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	LUC7L IMPDH2 MACF1 PSMD2 CHD4 PRKDC PLOD1 XAB2 PHLDB2	4.31e-04	1024	77	9	24711643
Pubmed	The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.	PSMD2 PRKDC	4.33e-04	14	77	2	21151955
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	TUT4 CLCN6 PIK3C2B CDK11A MACF1 TTC22 STIL PLOD1 RASAL2	4.53e-04	1031	77	9	16710414
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	LUC7L PIK3C2B YAE1 SIK2 UBAP1 PDCL FHIP2A TBC1D17 USP47	4.76e-04	1038	77	9	26673895
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1D CACNA1E	4.99e-04	15	77	2	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1D CACNA1E	4.99e-04	15	77	2	24453333
Pubmed	IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.	ACACA PRKDC	4.99e-04	15	77	2	18303054
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PTPN13 KIF15 DTNA PSMD2 NBEA PLOD1 TP53BP2 XPOT NIN	5.13e-04	1049	77	9	27880917
Pubmed	Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.	CDKN1B BRCA2 PRKDC	5.35e-04	71	77	3	28319113
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	RASIP1 ACACA PRKDC	5.58e-04	72	77	3	36376293
Pubmed	Variation within DNA repair pathway genes and risk of multiple sclerosis.	BRCA2 PRKDC XAB2	5.58e-04	72	77	3	20522537
Pubmed	Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	STIL NIN	5.69e-04	16	77	2	20301772
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	IMPDH2 MYO19 SIK2 FHIP2A XAB2 RASAL2 TBC1D17	5.98e-04	650	77	7	38777146
Pubmed	A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.	LUC7L IMPDH2 MTSS1	6.28e-04	75	77	3	15383276
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	IMPDH2 MAT2A PSMD2 CHD4 PRKDC PLOD1 XPOT	6.37e-04	657	77	7	36180527
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	LUC7L PTPN13 IMPDH2 ZNF618 MACF1 CHD4 PRKDC PLOD1 XAB2	6.40e-04	1082	77	9	38697112
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	MACF1 PRKDC USP47	6.53e-04	76	77	3	27542412
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	PTPN13 DTNA PSMD2 C2CD5 XPOT	6.65e-04	313	77	5	38270169
Pubmed	Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse.	CACNA1D DTNA	7.23e-04	18	77	2	33087486
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	NUDCD1 STIL RASAL2 PHLDB2	7.59e-04	184	77	4	32908313
Pubmed	UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.	LUC7L IMPDH2 MAT2A PSMD2 CHD4 PRKDC	7.81e-04	491	77	6	36273042
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	PIK3C2B PRKDC PHLDB2 TP53BP2	8.56e-04	190	77	4	15161933
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FCSK UAP1L1 USP47	9.04e-04	85	77	3	15449545
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	GBP6 DTNA SIK2 CDK11A CHD4 AZI2 PLOD1 C2CD5	9.12e-04	910	77	8	36736316
Pubmed	Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.	IMPDH2 CHD4 PRKDC	9.68e-04	87	77	3	24169447
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	IMPDH2 ACACA PRKDC XPOT	9.78e-04	197	77	4	31620119
Pubmed	The Role of CDKs and CDKIs in Murine Development.	CDKN1B CDK11A	9.89e-04	21	77	2	32731332
Pubmed	Isolation of differentially expressed genes from wild-type and Twist mutant mouse limb buds.	CHD4 STIL	9.89e-04	21	77	2	12124942
Pubmed	Genome-wide association studies identify four ER negative-specific breast cancer risk loci.	BRCA2 PIK3C2B	9.89e-04	21	77	2	23535733
Pubmed	Heritability and genetic association analysis of cognition in the Diabetes Heart Study.	KLHL2 MTSS1	9.89e-04	21	77	2	24684796
Pubmed	Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.	CACNA1D SLC4A7	9.89e-04	21	77	2	25249183
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	KLHL2 TUT4 SLC4A7 CDK11A CHD4 ZNF236 DNAH14 TBC1D17	1.01e-03	925	77	8	28986522
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	IMPDH2 MAT2A PSMD2 CHD4 PRKDC	1.01e-03	344	77	5	30333137
Pubmed	AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.	IMPDH2 MAT2A PSMD2 PRKDC	1.03e-03	200	77	4	35546148
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TUT4 PTPN13 ACACA MACF1 PLOD1 XAB2 NOL8	1.12e-03	724	77	7	36232890
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	ACACA BRCA2 CHD4 PRKDC XAB2	1.20e-03	357	77	5	37059091
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ACACA ZNF618 MYO19 NBEA PRKDC PARP14 DNAH14	1.23e-03	736	77	7	29676528
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	LUC7L IMPDH2 MACF1 PRKDC PHLDB2	1.26e-03	361	77	5	26167880
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	PSMD2 CHD4 PRKDC XPOT	1.26e-03	211	77	4	17314511
Pubmed	Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice.	TUT4 BRCA2	1.29e-03	24	77	2	26178733
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	LUC7L CDK11A CHD4 XAB2 NPM3	1.40e-03	370	77	5	22922362
GeneFamily	Calcium voltage-gated channel subunits	CACNA1D CACNA1E	2.24e-03	26	49	2	253
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	NBEA AKAP10	2.79e-03	29	49	2	396
Coexpression	GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP	CDKN1B NGEF PRKDC AZI2 STIL PARP14 RASAL2	2.08e-06	200	77	7	M6044
Coexpression	GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP	RASIP1 KLHL2 ACACA TSGA10 SIK2 PLOD1	2.77e-05	200	77	6	M5003
Coexpression	GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN	KLHL2 IMPDH2 ACACA BRCA2 MAT2A XPOT	2.77e-05	200	77	6	M4531
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	TUT4 SLC4A7 KIF15 BRCA2 YAE1 DTNA ZNF618 TSGA10 MACF1 CHD4 NUDCD1 PDCL STIL NPM3 NOL8	2.80e-05	1257	75	15	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	dev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#2_top-relative-expression-ranked_500	PIK3C2B MTSS1 RASAL2	5.38e-05	21	75	3	gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k2_500
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D SLC4A7 MACF1 NBEA CHD4 PHLDB2	1.13e-06	195	77	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D SLC4A7 MACF1 NBEA CHD4 PHLDB2	1.13e-06	195	77	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1D RASIP1 PIK3C2B TMOD4 PARP14	1.06e-05	167	77	5	774f3264318b002d0df5d06d41d645366038d0bf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 MYO19 STIL	1.12e-05	169	77	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RASIP1 ACACA SIK2 TTC22 FHIP2A	1.29e-05	174	77	5	a1f745962a104c6f4b86b7e482da8755384c773a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 PRKDC STIL	1.48e-05	179	77	5	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TUT4 MACF1 FHIP2A TP53BP2 NIN	1.97e-05	190	77	5	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	KNTC1 MACF1 PRKDC PARP14 MCOLN2	2.02e-05	191	77	5	9454f642c3621370fa23640b631301346b300950
ToppCell	Monocytes-Tissue-resident_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	TUT4 SLC4A7 DTNA ZNF618 RASAL2	2.12e-05	193	77	5	198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCell	PCW_07-8.5\|World / Celltypes from embryonic and fetal-stage human lung	BRCA2 MAT2A STIL DNAH14 NIN	2.17e-05	194	77	5	5759c83308df017f1faae248e9b85388e25254f0
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LUC7L SLC4A7 CDK11A MACF1 PARP14	2.46e-05	199	77	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Biopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	KNTC1 KIF15 BRCA2 MYO19 STIL	2.46e-05	199	77	5	4fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	KNTC1 KIF15 BRCA2 STIL IQCD	2.52e-05	200	77	5	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RASIP1 GBP6 PIK3C2B MACF1 PARP14	2.52e-05	200	77	5	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	RASIP1 GBP6 PIK3C2B MACF1 PARP14	2.52e-05	200	77	5	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RASIP1 GBP6 MTSS1 MACF1 PARP14	2.52e-05	200	77	5	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	KNTC1 KIF15 BRCA2 PRKDC STIL	2.52e-05	200	77	5	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	KNTC1 KIF15 BRCA2 PRKDC STIL	2.52e-05	200	77	5	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 PIK3C2B STIL RFX8	6.77e-05	126	77	4	4eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCell	severe-unassigned\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CACNA1E RASIP1 BRCA2 DTNA	7.20e-05	128	77	4	bef9cf0078fa8498d63f0723f1fa4a3c92405e10
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SLC4A7 TMOD4 MACF1 MCOLN2	8.85e-05	135	77	4	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	TUT4 SLC4A7 MACF1 MCOLN2	1.36e-04	151	77	4	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Mast\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM273 HPGDS ZNF483 DNAH14	1.36e-04	151	77	4	9702575e47ececcf0a9f0f20a4a920dbb1ba5657
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM273 HPGDS ZNF483 DNAH14	1.36e-04	151	77	4	673e4ab117b723c14d1df3804bbedc9e48284a9d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D KIF15 GPR179 TBC1D17	1.74e-04	161	77	4	9f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KNTC1 KIF15 BRCA2 STIL	1.83e-04	163	77	4	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	1.83e-04	163	77	4	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	RSV-Healthy-6\|Healthy / Virus stimulation, Condition and Cluster	GCNA CLCN6 PBLD BRICD5	1.87e-04	164	77	4	1b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCell	RSV-Healthy-6\|RSV / Virus stimulation, Condition and Cluster	GCNA CLCN6 PBLD BRICD5	1.87e-04	164	77	4	ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	1.92e-04	165	77	4	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	2.01e-04	167	77	4	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	2.10e-04	169	77	4	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KNTC1 KIF15 BRCA2 STIL	2.10e-04	169	77	4	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	NS-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NGEF STIL IQCD CCDC171	2.15e-04	170	77	4	f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF15 PIK3C2B STIL MCOLN2	2.15e-04	170	77	4	e08a6c5ac34c456da8c7318f104e06fca585be1f
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 KIF15 HPGDS TMOD4	2.20e-04	171	77	4	41932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 ACACA CCDC171 NPM3	2.30e-04	173	77	4	6e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ACACA PIK3C2B NOL8	2.30e-04	173	77	4	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ACACA PIK3C2B NOL8	2.30e-04	173	77	4	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	facs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN13 ACACA CCDC171 NPM3	2.30e-04	173	77	4	4c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	2.35e-04	174	77	4	84da9faff088d05233183b425385beb054c92d1b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	2.35e-04	174	77	4	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IMPDH2 KIF15 BRCA2 STIL	2.35e-04	174	77	4	46cbb462173a684ceb9e680f9259dc3b133763f7
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	RASIP1 ACACA SIK2 FHIP2A	2.40e-04	175	77	4	78a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	2.40e-04	175	77	4	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D TUT4 NGEF PHLDB2	2.45e-04	176	77	4	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC4A7 ACACA NBEA GPR179	2.45e-04	176	77	4	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	facs-GAT-Fat-24m-Lymphocytic-B_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E PIK3C2B MTSS1 MCOLN2	2.50e-04	177	77	4	f4afe10522eed77318954210224496f09d372532
ToppCell	control-Others-CD34+_GATA2+_cells\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	IMPDH2 HPGDS ZNF618 CCDC171	2.56e-04	178	77	4	2120bd3e099b0b271bf079db9827a2f3eee2f909
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E BRCA2 STIL CCDC171	2.61e-04	179	77	4	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E BRCA2 STIL CCDC171	2.61e-04	179	77	4	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1E SLC4A7 DNAH14 CCDC144A	2.61e-04	179	77	4	747a32460b257fffca30527b56a74720eb9c12e4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	2.61e-04	179	77	4	80112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	2.67e-04	180	77	4	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KNTC1 KIF15 BRCA2 STIL	2.67e-04	180	77	4	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	2.67e-04	180	77	4	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 MTSS1 MACF1 NIN	2.78e-04	182	77	4	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	KNTC1 KIF15 BRCA2 STIL	2.84e-04	183	77	4	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	KNTC1 KIF15 BRCA2 ZNF483	2.84e-04	183	77	4	a716b446c2bf5aa294b8f580aa845098fae76354
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1E PIK3C2B MTSS1 MCOLN2	2.96e-04	185	77	4	5fd4a3776259c96cf2dcb87f050af8226acbbda9
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	KNTC1 MACF1 PRKDC MCOLN2	2.96e-04	185	77	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	KNTC1 KIF15 BRCA2 STIL	2.96e-04	185	77	4	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 MACF1 CHD4 NIN	2.96e-04	185	77	4	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	CF-Myeloid-cDC\|CF / Disease state, Lineage and Cell class	BRCA2 ZNF618 TBC1D17 MCOLN2	2.96e-04	185	77	4	7f3d118845ff9f5f525796b0bbc6532a8ee323ab
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1E PIK3C2B MTSS1 MCOLN2	2.96e-04	185	77	4	4c55fa96877ab9a00fcbec3fb70fd2208d222527
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASIP1 PIK3C2B MTSS1 PHLDB2	3.02e-04	186	77	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KLHL2 PTPN13 ACACA DNAH14	3.02e-04	186	77	4	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	CV-Severe-3\|Severe / Virus stimulation, Condition and Cluster	KNTC1 BRCA2 STIL PHLDB2	3.09e-04	187	77	4	68cb43a73945f5e252530da25613f6b3f484b4d5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	3.09e-04	187	77	4	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	3.09e-04	187	77	4	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 PIK3C2B MTSS1 MACF1	3.15e-04	188	77	4	1f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 PIK3C2B MTSS1 MACF1	3.15e-04	188	77	4	85746f95319e494efdc1bbc24331698688d3a900
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	CACNA1D PTPN13 ACACA DNAH14	3.15e-04	188	77	4	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	COVID-19_Severe-HSPC\|COVID-19_Severe / disease group, cell group and cell class	IMPDH2 HPGDS CCDC171 DNAH14	3.21e-04	189	77	4	96015439971e2e5b8d6294ca5a6b873c7774e925
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KNTC1 KIF15 BRCA2 IQCD	3.21e-04	189	77	4	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KLHL2 MTSS1 MCOLN2 NIN	3.28e-04	190	77	4	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 KIF15 BRCA2 STIL	3.28e-04	190	77	4	31de1727822e9818652946dfb962daee77ffad68
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MACF1 CHD4 PHLDB2 NIN	3.28e-04	190	77	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RASIP1 PIK3C2B MTSS1 RASAL2	3.28e-04	190	77	4	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KNTC1 KIF15 BRCA2 STIL	3.28e-04	190	77	4	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	KNTC1 KIF15 BRCA2 STIL	3.28e-04	190	77	4	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KNTC1 KIF15 BRCA2 STIL	3.34e-04	191	77	4	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A7 TSGA10 UBAP1 DNAH14	3.34e-04	191	77	4	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC4A7 TSGA10 UBAP1 DNAH14	3.34e-04	191	77	4	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	CACNA1D DTNA MACF1 MCOLN2	3.41e-04	192	77	4	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTSS1 CHD4 STIL PARP14	3.48e-04	193	77	4	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	KNTC1 KIF15 BRCA2 STIL	3.48e-04	193	77	4	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D PTPN13 TSGA10 DNAH14	3.48e-04	193	77	4	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	CACNA1D DTNA MACF1 MCOLN2	3.48e-04	193	77	4	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KNTC1 KIF15 BRCA2 STIL	3.48e-04	193	77	4	e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KNTC1 KIF15 BRCA2 STIL	3.55e-04	194	77	4	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	3'_v3-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	KNTC1 KIF15 BRCA2 STIL	3.55e-04	194	77	4	bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D PTPN13 TSGA10 DNAH14	3.55e-04	194	77	4	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RASIP1 PIK3C2B PARP14 RASAL2	3.55e-04	194	77	4	fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KNTC1 KIF15 BRCA2 PRKDC	3.62e-04	195	77	4	cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KNTC1 KIF15 BRCA2 MYO19	3.62e-04	195	77	4	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	KNTC1 KIF15 BRCA2 STIL	3.62e-04	195	77	4	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	Healthy/Control-T/NK_proliferative\|Healthy/Control / Disease group and Cell class	KNTC1 KIF15 BRCA2 STIL	3.62e-04	195	77	4	957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCell	CV-Severe-2\|CV / Virus stimulation, Condition and Cluster	TMEM273 IMPDH2 MAT2A NPM3	3.62e-04	195	77	4	1cde7f6e6c9c610bacc79014519447112c27dd9d
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KNTC1 KIF15 BRCA2 STIL	3.62e-04	195	77	4	1a5e814e12fe37287dbfc58189e1958e2c76b5da
Disease	infertility (implicated_via_orthology)	CDKN1B BRCA2	1.26e-04	7	73	2	DOID:5223 (implicated_via_orthology)
Disease	Beta blocking agent use measurement	CACNA1D SLC4A7 CLCN6 SIK2	1.87e-04	114	73	4	EFO_0009929
Disease	Malignant neoplasm of kidney	CDKN1B BRCA2 HPGDS	1.91e-04	45	73	3	C0740457
Disease	Global developmental delay	FCSK CACNA1E NBEA FHIP2A	3.37e-04	133	73	4	C0557874
Disease	diet measurement	RASIP1 ZNF618 NGEF SIK2 UBAP1 AKAP10 PRKDC CCDC171 DNAH14	1.11e-03	1049	73	9	EFO_0008111
Disease	peripheral arterial disease, traffic air pollution measurement	MTSS1 MACF1 NBEA XAB2	1.38e-03	194	73	4	EFO_0004265, EFO_0007908
Disease	Adenocarcinoma of lung (disorder)	SLC4A7 IMPDH2 PRKDC NPM3	1.72e-03	206	73	4	C0152013
Disease	Seizures	FCSK CACNA1E MACF1 NBEA	2.12e-03	218	73	4	C0036572
Disease	resistin measurement	PSMD2 XAB2	2.35e-03	29	73	2	EFO_0004819

Protein segments in the cluster

Peptide	Gene	Start	Entry
MDALVEDDICILNHE	AZI2	1	Q9H6S1
EAMTRDSSDEHCVDI	CACNA1E	421	Q15878
EHQVCFLRLMEDSDR	BRICD5	121	Q6PL45
ECDSAHSLRLEMARA	AKAP10	241	O43572
DVMRAVREHEDLCQV	IQCD	86	Q96DY2
LETEHMDCSDLLRRQ	CCDC171	241	Q6TFL3
DCDIEDDRLAAMFRE	ACACA	1296	Q13085
LTRDLEKHCRDMEEA	CDKN1B	41	P46527
GDCMTIIHREDEDEI	TP53BP2	1081	Q13625
DLELCDEAMALLDEV	RASIP1	681	Q5U651
AAVCLLENELDEDMH	PBLD	21	P30039
DSTHIICDNDEMLRV	INTS9	631	Q9NV88
CAAIAERLMHLTSEE	NUDCD1	376	Q96RS6
AMDHLESFIAECDRR	LUC7L	86	Q9NQ29
IERDMLCEDLAHATE	KIF15	1056	Q9NS87
EEDDAEHVLALTMLC	NPM3	56	O75607
EMVDEVCEDELDLQH	GPR179	641	Q6PRD1
LEEDCFEVTREAMLH	MYO19	271	Q96H55
SVQHDEEVCLDEMRD	MAT2A	206	P31153
HDCFLEEIMTKREDL	IMPDH2	171	P12268
CHVDAIVDTLDDFMS	HPGDS	86	O60760
EEMEACEELALALSR	MTSS1	471	O43312
DLVMSEVDRCGEHDV	RASAL2	351	Q9UJF2
HESMAVRLVTELCLE	KNTC1	1956	P50748
ELLDMHAACEREAIA	GBP6	351	Q6ZN66
SCHDSDDDIMRNDRE	NOL8	361	Q76FK4
IEASEAECRHMLEEE	MACF1	5181	Q9UPN3
AECRHMLEEEGTLDL	MACF1	5186	Q9UPN3
FTEVACDELVEEMEH	PLOD1	561	Q02809
ERDEEVAAFCHMLDI	PIK3C2B	331	O00750
EQEIRSTSLHCMEDE	OFCC1	191	Q8IZS5
IEEINDEMRRCHCEL	PARP14	341	Q460N5
FDILHCMAENVTRED	FCSK	266	Q8N0W3
LRNMCDEHIASEEPA	CLCN6	686	P51797
RMDHVDRCFDVLAVE	KLHL26	516	Q53HC5
SEECRDADLHVIMNA	BRCA2	1156	P51587
DSLEEGELRDHCMEI	CDK11A	46	Q9UQ88
LMCHLEEVADLVVLD	DNAH14	1046	Q0VDD8
SCMLESSNRLDEEHR	DTNA	421	Q9Y4J8
DSADRIRDTLIHEMC	GCNA	581	Q96QF7
LIEHCDHISDEISIM	FHIP2A	456	Q5W0V3
DLFHEDCMLQEEIAL	CCDC144A	816	A2RUR9
LEEEDDHHMEFCRVC	CHD4	441	Q14839
EIDDTDAMEDVHSLL	C2CD5	681	Q86YS7
HEIADACDLTIDEME	CACNA1D	2086	Q01668
HRDSEMKEECLREDL	MCOLN2	31	Q8IZK6
HETSECLELAMEISE	MDFIC2	171	A0A1B0GVS7
DILEERMHCDDETSL	PTPN13	686	Q12923
LSMTCRSHLDEEEEQ	PDCL	91	Q13371
IEVLSDEHAREMCLR	XAB2	656	Q9HCS7
EHIPHDLFTEMDELC	SLC4A7	106	Q9Y6M7
EELTDLCHMLSLEEV	NIN	31	Q8N4C6
EHEACDLLMEIEQVD	PSMD2	201	Q13200
AADRREEEKMCDHLI	NBEA	2011	Q8NFP9
EHRMEENIVISDVCD	NGEF	336	Q8N5V2
SEDCEHLIRRMLVLD	SIK2	241	Q9H0K1
DESFRELDMECALLD	PHLDB2	616	Q86SQ0
QELCSREMIVHSVDD	STIL	131	Q15468
HLLVACAILDMERDT	TBC1D17	526	Q9HA65
CMDRVEEILELAAAD	TTLL8	366	A6PVC2
RSMHEVIELLNVCED	ZNF618	656	Q5T7W0
LLVEEALEMHQCSEE	UBAP1	441	Q9NZ09
EEDACQLQEMRHELE	SOGA3	386	Q5TF21
MIHILQSCLEEEEEE	RFX8	436	Q6ZV50
HDVQELCRVMFDALE	USP47	271	Q96K76
CALEDHKILEDMERR	UAP1L1	231	Q3KQV9
LEEALAHATDAEMCD	TMOD4	116	Q9NZQ9
LELEMDELNRHECMA	PRKDC	2081	P78527
ELECTVHNLDDERME	TSGA10	146	Q9BZW7
VDLLDSIEDMDLCHV	YAE1	131	Q9NRH1
LGHMSIEVLREEACD	XPOT	231	O43592
RCLRDDDHGLMEESQ	ZNF483	251	Q8TF39
ICMEEEEEHSDRNAS	ZNF236	1091	Q9UL36
RDSDLDICMTLEGHE	TUT4	1006	Q5TAX3
ICMIRRHLFDDDSSD	TMEM273	56	Q5T292
CREDECALMLLEHGT	POTEG	216	Q6S5H5
EEEEEACAARLADLM	TTC22	116	Q5TAA0
DESPVSICEDHEMRN	ZNF114	116	Q8NC26
CDVTIVAEDMEISAH	KLHL2	56	O95198